@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQE6: (2017-11-26 )
MELRHLRYFVTVVEEQSLTKAAEKLFIAQPPLTRQIKKLEEELGIDLFEKGSRPLKVTEAGLFFYQHAVQILTHTAQAASMAKKMKLVENVVKVGYVSSLLYGRLPQVIYLFRQKNPDIHVELIECGTRDQVEALKLGKIDLGFGRLPISDPAIKRLLLRKEKLKLAIHKKHPLSDFQESGIYLSQIINETIFSYPTTPKPNFSTTIQALFTKLGLVPAKLTEVREIHMSLGLVASGEGICIIPESACDIGMKNLTYLNILDLEAYSPISLSMRNMDQSSYIPKILDCIEEIYGEEEVSRNLNL
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MEL
R
H
L
R
Y
F
V
T
V
V
E
E
Q
S
L
T
K
A
A
E
K
LFIAQP
P
L
T
R
Q
I
K
K
L
E
E
E
LG
I
D
L
F
EKGSR
P
L
K
V
T
E
A
G
L
F
F
Y
Q
H
A
V
Q
I
L
T
H
T
A
Q
A
A
S
M
A
K
K
M
K
L
V
E
N
V
V
K
V
G
Y
V
S
S
L
L
Y
GR
L
P
Q
V
I
Y
L
F
RQKNP
D
I
H
V
E
L
IECGTR
D
Q
V
E
A
LKLG
K
I
D
LGFGRLPIS
D
P
A
I
K
R
L
L
L
R
K
E
K
L
K
L
A
I
HKKHPL
S
D
F
Q
ES
G
I
Y
L
S
Q
I
I
N
E
T
I
FSYPTTPKPN
F
S
T
T
I
Q
A
L
F
T
KLGLV
P
A
K
L
T
E
V
R
E
I
H
M
SLGLVASG
E
G
I
C
I
I
PE
S
A
CDIGMKN
L
T
Y
L
N
I
LDLEAYSP
I
S
L
S
M
RNMDQSS
Y
I
P
K
I
L
D
C
I
E
E
I
Y
G
E
E
E
V
S
RNLNL
22
PsiBlast_CBE
92.34
54%
-142
- C1 -
-
3K1M
2
BENM_ACIAD
B:
[1-296]
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
N
V
D
Q
M
V
S
M
T
K
R
I
A
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
21
PsiBlast_CBE
90.60
54%
-138
- C1 -
-
3K1N
1
BENM_ACIAD
B:
[1-296]
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
N
V
D
Q
M
V
S
M
T
K
R
I
A
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
4
PsiBlast_PDB
89.82
54%
-142
- C1 -
-
3K1M
2
BENM_ACIAD
A:
[1-296]
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
N
V
D
Q
M
V
S
M
T
K
R
I
A
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
2
PsiBlast_PDB
89.18
54%
-139
- C1 -
-
3K1N
1
BENM_ACIAD
A:
[1-296]
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
N
V
D
Q
M
V
S
M
T
K
R
I
A
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
3
PsiBlast_PDB
85.86
54%
-122
- C- -
-
3K1P
-
BENM_ACIAD
A:
[1-296]
M
E
L
R
H
L
R
Y
F
V
A
V
V
E
E
Q
S
F
T
K
A
A
D
K
L
C
I
A
Q
P
P
L
S
R
Q
I
Q
N
L
E
E
E
L
G
I
Q
L
L
E
R
G
S
R
P
V
K
T
T
P
E
G
H
F
F
Y
Q
Y
A
I
K
L
L
S
N
V
D
Q
M
V
S
M
T
K
R
I
A
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
K
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
1
PsiBlast_PDB
81.89
70%
-148
- C1 -
-
2H98
-
CATM_ACIAD
A:
[89-298]
----------------------------------------------------------------------------------------
S
Q
T
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
R
I
M
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
52
HHSearch
81.81
70%
-148
- C1 -
-
2H98
-
CATM_ACIAD
A:
[89-299]
----------------------------------------------------------------------------------------
S
Q
T
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
R
I
M
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
R
-----
8
PsiBlast_PDB
80.65
63%
-153
- C1 -
-
2F7C
1
CATM_ACIAD
A:
[9-218]
----------------------------------------------------------------------------------------
S
Q
T
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
R
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
P
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
7
PsiBlast_PDB
80.31
63%
-159
- C1 -
-
2F7B
-
CATM_ACIAD
A:
[10-218]
-----------------------------------------------------------------------------------------
Q
T
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
R
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
P
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
26
PsiBlast_CBE
79.64
65%
-155
- C1 -
-
3GLB
3
CATM_ACIAD
C:
[4-210]
-------------------------------------------------------------------------------------------
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
H
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
9
PsiBlast_PDB
78.96
65%
-152
- C1 -
-
3GLB
2
CATM_ACIAD
A:
[4-210]
-------------------------------------------------------------------------------------------
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
H
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
25
PsiBlast_CBE
78.92
65%
-157
- C1 -
-
3GLB
3
CATM_ACIAD
D:
[4-210]
-------------------------------------------------------------------------------------------
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
H
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
27
PsiBlast_CBE
78.40
65%
-155
- C1 -
-
3GLB
2
CATM_ACIAD
B:
[4-210]
-------------------------------------------------------------------------------------------
L
R
I
G
Y
V
S
S
L
L
Y
G
L
L
P
E
I
I
Y
L
F
R
Q
Q
N
P
E
I
H
I
E
L
I
E
C
G
T
K
D
Q
I
N
A
L
K
Q
G
K
I
D
L
G
F
G
R
L
K
I
T
D
P
A
I
R
H
I
V
L
H
K
E
Q
L
K
L
A
I
H
K
H
H
H
L
N
Q
F
A
A
T
G
V
H
L
S
Q
I
I
D
E
P
M
L
L
Y
P
V
S
Q
K
P
N
F
A
T
F
I
Q
S
L
F
T
E
L
G
L
V
P
S
K
L
T
E
I
R
E
I
Q
L
A
L
G
L
V
A
A
G
E
G
V
C
I
V
P
A
S
A
M
D
I
G
V
K
N
L
L
Y
I
P
I
L
D
D
D
A
Y
S
P
I
S
L
A
V
R
N
M
D
H
S
N
Y
I
P
K
I
L
A
C
V
Q
E
V
F
A
T
H
H
I
------
53
HHSearch
75.39
54%
-139
- C1 -
-
2H9B
-
BENM_ACIAD
B:
[89-299]
----------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
S
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
G
F
T
-----
6
PsiBlast_PDB
74.93
54%
-138
- C1 -
-
2H9B
-
BENM_ACIAD
A:
[89-296]
----------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
S
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
24
PsiBlast_CBE
74.83
54%
-136
- C1 -
-
2H99
1
BENM_ACIAD
B:
[89-296]
----------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
S
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
5
PsiBlast_PDB
74.82
54%
-135
- C1 -
-
2H99
-
BENM_ACIAD
A:
[90-296]
-----------------------------------------------------------------------------------------
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
H
S
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
30
PsiBlast_CBE
73.64
49%
-149
- C1 -
-
2F78
3
BENM_ACIAD
B:
[10-216]
-----------------------------------------------------------------------------------------
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
14
PsiBlast_PDB
73.53
49%
-131
- C1 -
-
2F97
4
BENM_ACIAD
A:
[9-216]
----------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
11
PsiBlast_PDB
73.34
49%
-139
- C1 -
-
2F78
2
BENM_ACIAD
A:
[7-216]
--------------------------------------------------------------------------------------
S
V
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
13
PsiBlast_PDB
73.08
49%
-138
- C1 -
-
2F8D
6
BENM_ACIAD
A:
[9-216]
----------------------------------------------------------------------------------------
E
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------
29
PsiBlast_CBE
71.90
49%
-140
- C1 -
-
2F7A
2
BENM_ACIAD
B:
[10-216]
-----------------------------------------------------------------------------------------
K
T
I
R
I
G
F
V
G
S
L
L
F
G
L
L
P
R
I
I
H
L
Y
R
Q
A
H
P
N
L
R
I
E
L
Y
E
M
G
T
K
A
Q
T
E
A
L
K
E
G
R
I
D
A
G
F
G
R
L
K
I
S
D
P
A
I
K
R
T
L
L
R
N
E
R
L
M
V
A
V
H
A
S
H
P
L
N
Q
M
K
D
K
G
V
H
L
N
D
L
I
D
E
K
I
L
L
Y
P
S
S
P
K
P
N
F
S
T
H
V
M
N
I
F
S
D
H
G
L
E
P
T
K
I
N
E
V
R
E
V
Q
L
A
L
G
L
V
A
A
G
E
G
I
S
L
V
P
A
S
T
Q
S
I
Q
L
F
N
L
S
Y
V
P
L
L
D
P
D
A
I
T
P
I
Y
I
A
V
R
N
M
E
E
S
T
Y
I
Y
S
L
Y
E
T
I
R
Q
I
Y
A
Y
E
--------