@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQK3: (2017-11-27 )
MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVAMQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAPLLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLVPMIRGMLSTIYVDLTEAGKQTDLQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVKGASGQAVQNMNLMFGFNEDEGLQGIGLLP
Atome Classification :
(20 SA)
.........10........20....-----....30....--..-..40......--------..50.......---.60----........70........80........90........100.......110.......120.......130.--......140.......150.......160..--....-.---170.......180.....-..190.......200.......-210.......220.......230.......240----.......250.......260.......270.......280---.----.......--290.......300..-..-....310.......320.......330.......340.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
I
S
V
G
I
VGGTGY
T
G
V
E
L
L
R
I
L
L
RHP-----K
A
Q
V
R
V
L
TSR--TE-AGK
P
V
A
D
M
FP--------NLRGHT
D
L
Q
F
S---DL
N
----
I
D
A
L
KEC
D
V
V
F
F
ATPH
G
V
A
M
Q
H
A
K
D
L
I
AAG
T
K
V
I
D
L
A
A
D
F
R
L
Q
N
L
E
Q
F
E
K
W
YGMEHA
C
P
D
V
L
K
D
S
V
Y
G
L
T
EL--
N
R
E
K
I
K
Q
A
QVIGNPGCYP
T
T
V
Q
L
G
L
A
P
L
L
K
S
--
A
Q
A
L
-
I
---ETK
N
I
I
I
DAKSGVSGAGR-K
A
S
L
G
M
I
YSENADN
F
K
A
YGVAG-HRH
H
P
E
I
V
E
A
L
E
N
IAG
K
K
D
V
F
E
G
L
L
F
V
P
H
L
V
P
M
----
I
R
G
M
L
S
T
I
Y
V
D
L
TEAGKQT
D
L
Q
A
L
Y
E
N
FYANE
K
F
V
D
V
MP----A----NSSPETR--SVRGA
N
E
L
R
I
A
L
-YK-PQ-P
N
K
L
I
I
L
AAQDNLVKGASG
Q
A
V
Q
N
M
N
L
M
F
GFNEDEGLQGIGLLP
2
PsiBlast_PDB
92.07
44%
-95
- C1 -
-
2Q49
-
ARGC_ARATH
A:
[17-359]
-
I
R
I
G
L
L
G
A
S
G
Y
T
G
A
E
I
V
R
L
L
A
N
H
P
-----
H
F
Q
V
T
L
M
T
A
D
--
R
K
-
A
G
Q
S
M
E
S
V
F
P
--------
H
L
R
A
Q
K
L
P
T
L
V
---
S
V
K
----
D
A
D
F
S
T
V
D
A
V
F
C
C
L
P
H
G
T
T
Q
E
I
I
K
E
L
P
T
A
-
L
K
I
V
D
L
S
A
D
F
R
L
R
N
I
A
E
Y
E
E
W
Y
G
Q
P
H
K
A
V
E
L
Q
K
E
V
V
Y
G
L
T
E
I
--
L
R
E
D
I
K
K
A
R
L
V
A
N
P
G
C
Y
P
T
T
I
Q
L
P
L
V
P
L
L
K
A
----
N
L
-
I
---
K
H
E
N
I
I
I
D
A
K
S
G
V
S
G
A
G
R
-
G
A
K
E
A
N
L
Y
S
E
I
A
E
G
I
S
S
Y
G
V
T
R
-
H
R
H
V
P
E
I
E
Q
G
L
S
D
V
A
Q
S
K
V
T
V
S
---
F
T
P
H
L
M
P
M
----
I
R
G
M
Q
S
T
I
Y
V
E
M
A
P
G
V
R
T
E
D
L
H
Q
Q
L
K
T
S
Y
E
D
E
E
F
V
K
V
L
D
----
E
----
G
V
V
P
R
T
H
--
N
V
R
G
S
N
Y
C
H
M
S
V
-
F
P
-
D
R
I
P
G
R
A
I
I
I
S
V
I
D
N
L
V
K
G
A
S
G
Q
A
L
Q
N
L
N
I
M
L
G
Y
P
E
T
T
G
L
L
H
Q
P
L
F
P
1
PsiBlast_PDB
91.48
44%
-99
- C1 -
-
1XYG
-
ARGC_ARATH
A:
[17-359]
-
I
R
I
G
L
L
G
A
S
G
Y
T
G
A
E
I
V
R
L
L
A
N
H
P
-----
H
F
Q
V
T
L
M
T
A
D
--
R
K
-
A
G
Q
S
M
E
S
V
F
P
--------
H
L
R
A
Q
K
L
P
T
L
V
---
S
V
K
----
D
A
D
F
S
T
V
D
A
V
F
C
C
L
P
H
G
T
T
Q
E
I
I
K
E
L
P
T
A
-
L
K
I
V
D
L
S
A
D
F
R
L
R
N
I
A
E
Y
E
E
W
Y
G
Q
P
H
K
A
V
E
L
Q
K
E
V
V
Y
G
L
T
E
I
--
L
R
E
D
I
K
K
A
R
L
V
A
N
P
G
C
Y
P
T
T
I
Q
L
P
L
V
P
L
L
K
A
----
N
L
-
I
---
K
H
E
N
I
I
I
D
A
K
S
G
V
S
G
A
G
R
-
G
A
K
E
A
N
L
Y
S
E
I
A
E
G
I
S
S
Y
G
V
T
R
-
H
R
H
V
P
E
I
E
Q
G
L
S
D
V
A
Q
S
K
V
T
V
S
---
F
T
P
H
L
M
P
M
----
I
R
G
M
Q
S
T
I
Y
V
E
M
A
P
G
V
R
T
E
D
L
H
Q
Q
L
K
T
S
Y
E
D
E
E
F
V
K
V
L
D
----
E
----
G
V
V
P
R
T
H
--
N
V
R
G
S
N
Y
C
H
M
S
V
-
F
P
-
D
R
I
P
G
R
A
I
I
I
S
V
I
D
N
L
V
K
G
A
S
G
Q
A
L
Q
N
L
N
I
M
L
G
Y
P
E
T
T
G
L
L
H
Q
P
L
F
P
3
PsiBlast_PDB
90.43
45%
-83
- C1 -
-
1VKN
-
ARGC_THEMA
A:
[2-339]
-
I
R
A
G
I
I
G
A
T
G
Y
T
G
L
E
L
V
R
L
L
K
N
H
P
-----
E
A
K
I
T
Y
L
S
S
R
--
T
Y
-
A
G
K
K
L
E
E
I
F
P
--------
S
T
L
E
N
S
I
L
S
E
F
---
D
P
E
-----
K
V
S
K
N
C
D
V
L
F
T
A
L
P
A
G
A
S
Y
D
L
V
R
E
L
--
K
G
V
K
I
I
D
L
G
A
D
F
R
F
D
D
P
G
V
Y
R
E
W
Y
G
K
E
L
S
G
Y
E
N
I
K
-
R
V
Y
G
L
P
E
L
--
H
R
E
E
I
K
N
A
Q
V
V
G
N
P
G
C
Y
P
T
S
V
I
L
A
L
A
P
A
L
K
----
H
N
L
-
V
---
D
P
E
T
I
L
V
D
A
K
S
G
V
S
G
A
G
R
-
K
E
K
V
D
Y
L
F
S
E
V
N
E
S
L
R
P
Y
N
V
A
K
-
H
R
H
V
P
E
M
E
Q
E
L
G
K
I
S
G
K
K
---
V
N
V
V
F
T
P
H
L
V
P
M
----
T
R
G
I
L
S
T
I
Y
V
K
T
D
K
S
L
E
E
--
I
H
E
A
Y
L
E
F
Y
K
N
E
P
F
V
H
V
L
P
----
M
----
G
I
Y
P
S
T
K
--
W
C
Y
G
S
N
H
V
F
I
G
M
Q
M
E
-
E
R
-
T
N
T
L
I
L
M
S
A
I
D
N
L
V
K
G
A
S
G
Q
A
V
Q
N
M
N
I
M
F
G
L
D
E
T
K
G
L
E
F
T
P
I
Y
P
39
HHSearch
85.67
45%
-73
- C1 -
-
2Q49
-
ARGC_ARATH
A:
[16-359]
D
I
R
I
G
L
L
G
A
S
G
Y
T
G
A
E
I
V
R
L
L
A
N
H
P
-----
H
F
Q
V
T
L
M
T
A
D
--
R
K
-
A
G
Q
S
M
E
S
V
F
P
--------
H
L
R
A
Q
K
L
P
T
L
V
---
S
V
K
----
D
A
D
F
S
T
V
D
A
V
F
C
C
L
P
H
G
T
T
Q
E
I
I
K
E
L
-
P
T
A
L
K
I
V
D
L
S
A
D
F
R
L
R
N
I
A
E
Y
E
E
W
Y
G
Q
P
H
K
A
V
E
L
Q
K
E
V
V
Y
G
L
T
E
I
--
L
R
E
D
I
K
K
A
R
L
V
A
N
P
G
C
Y
P
T
T
I
Q
L
P
L
V
P
L
L
K
A
--
N
-
L
I
K
H
---
E
--
N
I
I
I
D
A
K
S
G
V
S
G
A
G
R
-
G
A
K
E
A
N
L
Y
S
E
I
A
E
G
I
S
S
Y
G
V
T
R
-
H
R
H
V
P
E
I
E
Q
G
L
S
D
V
A
Q
---
S
K
V
T
V
S
F
T
P
H
L
M
P
M
----
I
R
G
M
Q
S
T
I
Y
V
E
M
A
P
G
V
R
T
E
D
L
H
Q
Q
L
K
T
S
Y
E
D
E
E
F
V
K
V
L
D
----------
E
G
V
V
P
R
TH
N
V
R
G
S
N
Y
C
H
M
S
V
-
F
P
D
R
I
-
P
G
R
A
I
I
I
S
V
I
D
N
L
V
K
G
A
S
G
Q
A
L
Q
N
L
N
I
M
L
G
Y
P
E
T
T
G
L
L
H
Q
P
L
F
P
6
PsiBlast_PDB
83.46
35%
-85
- C1 -
-
5EIO
3
LYSY_THET2
A:
[5-344]
--
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
-----
I
P
----
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
C
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
----
G
V
-
L
---
K
P
T
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
---
E
N
L
P
G
R
P
E
V
--------
H
L
T
A
I
A
T
DR
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
QKKG
V
----
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
E
L
E
-
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
37
HHSearch
83.17
37%
-77
- C1 -
-
5EIN
14
LYSY_THET2
A:
[3-344]
K
K
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
I
---
P
------
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
A
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
--
G
-
V
L
K
P
---
T
--
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
E
N
L
P
G
-------
R
P
E
V
H
L
T
A
I
A
T
D
R
----
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
----
Q
KKGV
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
-
E
L
E
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
9
PsiBlast_PDB
83.01
35%
-85
- C1 -
-
5EIN
14
LYSY_THET2
A:
[5-344]
--
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
-----
I
P
----
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
A
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
----
G
V
-
L
---
K
P
T
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
---
E
N
L
P
G
R
P
E
V
--------
H
L
T
A
I
A
T
DR
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
QKKG
V
----
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
E
L
E
-
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
21
PsiBlast_CBE
82.47
35%
-87
- C1 -
-
5EIO
4
LYSY_THET2
B:
[5-344]
--
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
-----
I
P
----
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
C
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
----
G
V
-
L
---
K
P
T
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
---
E
N
L
P
G
R
P
E
V
--------
H
L
T
A
I
A
T
DR
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
Q
KKG
V
----
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
E
L
E
-
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
36
HHSearch
81.95
37%
-77
- C1 -
-
5EIN
10
LYSY_THET2
B:
[3-344]
K
K
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
I
---
P
------
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
A
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
--
G
-
V
L
K
P
---
T
--
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
E
N
L
P
G
-------
R
P
E
V
H
L
T
A
I
A
T
D
R
----
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
----
Q
KKGV
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
-
E
L
E
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
7
PsiBlast_PDB
81.88
35%
-82
- C1 -
-
2OZP
-
?
A:
[6-345]
--
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
-----
V
P
----
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
V
L
V
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
R
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
C
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
----
G
V
-
L
---
K
P
T
P
I
F
V
T
L
L
I
S
T
S
A
G
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
---
E
N
L
P
G
R
P
E
V
--------
H
L
T
A
I
A
T
DR
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
QKKG
V
----
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
E
L
E
-
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
22
PsiBlast_CBE
81.59
35%
-83
- C1 -
-
5EIN
10
LYSY_THET2
B:
[5-344]
--
T
L
S
I
V
G
A
S
G
Y
A
G
G
E
F
L
R
L
A
L
S
H
P
-----
Y
L
E
V
K
Q
V
T
S
R
--
R
F
-
A
G
E
P
V
H
F
V
H
P
--------
N
L
R
G
R
T
N
L
K
F
-----
I
P
----
P
E
K
L
E
P
A
D
I
L
V
L
A
L
P
H
G
V
F
A
R
E
F
D
R
Y
S
A
L
A
P
I
L
I
D
L
S
A
D
F
R
L
K
D
P
E
L
Y
R
R
Y
Y
G
-
E
H
P
R
P
D
L
L
G
C
F
V
Y
A
V
P
E
L
--
Y
R
E
A
L
K
G
A
D
W
I
A
G
A
G
A
N
A
T
A
T
L
L
G
L
Y
P
L
L
K
A
----
G
V
-
L
---
K
P
T
P
I
F
V
T
L
L
I
S
T
S
A
A
G
A
-
E
A
S
P
A
S
H
H
P
E
R
A
G
S
I
R
V
Y
K
P
T
G
-
H
R
H
T
A
E
V
V
---
E
N
L
P
G
R
P
E
V
--------
H
L
T
A
I
A
T
DR
V
R
G
I
L
M
T
A
Q
C
F
V
Q
D
G
W
S
E
R
D
V
W
Q
A
Y
R
E
A
Y
A
G
E
P
F
I
R
L
V
K
Q
KKG
V
----
H
R
Y
P
D
P
R
--
F
V
Q
G
T
N
Y
A
D
I
G
F
E
L
E
-
E
D
-
T
G
R
L
V
V
M
T
A
I
D
N
L
V
K
G
T
A
G
H
A
L
Q
A
L
N
V
R
M
G
W
P
E
T
L
G
L
D
F
P
G
L
H
P
38
HHSearch
74.69
39%
-27
- C1 -
-
2G17
-
ARGC_SALTY
A:
[4-337]
M
L
N
T
L
I
V
G
A
S
G
Y
A
G
A
E
L
V
S
Y
V
N
R
H
P
-----
H
M
T
I
T
A
L
T
V
S
AQ
S
N
D
A
G
K
L
I
S
D
L
H
P
--------
Q
L
K
G
I
V
D
L
P
L
Q
P
M
S
D
V
R
-----
D
F
S
A
D
V
D
V
V
F
L
A
T
A
H
E
V
S
H
D
L
A
P
Q
F
L
Q
A
G
C
V
V
F
D
L
S
G
A
F
R
V
N
D
R
A
F
Y
E
K
Y
Y
G
F
T
H
Q
Y
P
E
L
L
E
Q
A
V
Y
G
L
A
E
W
--
N
V
D
K
L
N
T
A
N
L
I
A
V
P
G
C
Y
P
T
A
A
Q
L
S
L
K
P
L
I
D
G
----
G
L
-
L
DLT
Q
--
W
P
V
I
N
A
T
S
G
V
S
G
A
G
R
-
K
A
A
I
S
N
S
F
C
--
E
V
S
L
Q
P
Y
G
V
F
T
-
H
R
H
Q
P
E
I
A
V
H
L
G
---------
A
E
V
I
F
T
P
H
L
G
N
F
----
P
R
G
I
L
E
T
I
T
C
R
L
K
A
G
V
T
H
A
Q
V
A
D
V
L
Q
K
A
Y
G
D
K
P
L
V
R
L
Y
D
---------
K
G
V
P
A
L
K
--
N
V
V
G
L
P
F
C
D
I
G
F
-
A
V
-
Q
--
G
E
H
L
I
V
V
A
T
E
D
N
L
L
K
G
A
A
A
Q
A
V
Q
C
A
N
I
R
F
G
F
A
E
T
Q
S
L
I
------
32
HHSearch
73.19
49%
3
- C1 -
-
1VKN
-
ARGC_THEMA
A:
[1-339]
M
I
R
A
G
I
I
G
A
T
G
Y
T
G
L
E
L
V
R
L
L
K
N
H
P
-----
E
A
K
I
T
Y
L
S
S
R
--
T
Y
-
A
G
K
K
L
E
E
I
F
P
--------
S
T
L
E
-----
N
S
---
I
L
S
EFD
P
E
K
V
S
K
N
C
D
V
L
F
T
A
L
P
A
G
A
S
Y
D
L
V
R
E
L
--
K
G
V
K
I
I
D
L
G
A
D
F
R
F
D
D
P
G
V
Y
R
E
W
Y
G
K
E
L
S
G
Y
E
N
I
-
K
R
V
Y
G
L
P
E
L
--
H
R
E
E
I
K
N
A
Q
V
V
G
N
P
G
C
Y
P
T
S
V
I
L
A
L
A
P
A
L
K
H
NL
V
-
D
--
P
---
E
--
T
I
L
V
D
A
K
S
G
V
S
G
A
G
R
K
E
K
V
D
Y
L
-
F
S
E
V
N
E
S
L
R
P
Y
N
V
A
K
-
H
R
H
V
P
E
M
E
Q
E
L
G
K
I
S
G
K
---
K
V
N
V
V
F
T
P
H
L
V
P
M
----
T
R
G
I
L
S
T
I
Y
V
K
T
D
K
--
S
L
E
E
I
H
E
A
Y
L
E
F
Y
K
N
E
P
F
V
H
V
L
P
----
M
----
G
I
Y
P
S
T
K
--
W
C
Y
G
S
N
H
V
F
I
G
M
-
Q
M
E
E
R
-
T
N
T
L
I
L
M
S
A
I
D
N
L
V
K
G
A
S
G
Q
A
V
Q
N
M
N
I
M
F
G
L
D
E
T
K
G
L
E
F
T
P
I
Y
P
26
PsiBlast_CBE
71.66
36%
-6
- C1 -
-
2I3A
1
ARGC_MYCTU
B:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
A
Y
A
D
G
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
C
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
A
V
D
-
E
D
-
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
12
PsiBlast_PDB
71.45
36%
-9
- C- -
-
2NQT
-
ARGC_MYCTU
A:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
A
Y
A
D
G
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
-
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
-
A
V
-
D
E
D
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
25
PsiBlast_CBE
70.70
36%
-5
- C1 -
-
2I3A
1
ARGC_MYCTU
C:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
A
Y
A
D
G
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
C
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
A
V
D
-
E
D
-
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
11
PsiBlast_PDB
70.47
36%
-7
- C1 -
-
2I3G
2
ARGC_MYCTU
A:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
A
Y
A
D
G
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
C
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
A
V
D
-
E
D
-
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
10
PsiBlast_PDB
70.36
36%
-7
- C1 -
-
2I3A
1
ARGC_MYCTU
A:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
A
Y
A
D
G
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
C
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
A
V
D
-
E
D
-
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
24
PsiBlast_CBE
70.29
36%
-7
- C1 -
-
2I3A
1
ARGC_MYCTU
D:
[12-352]
---
V
A
V
A
G
A
S
G
Y
A
G
G
E
I
L
R
L
L
L
G
H
P
AYADG
R
L
R
I
G
A
L
T
A
A
--
T
S
-
A
G
S
T
L
G
E
H
H
P
--------
H
L
T
P
L
A
H
R
V
V
E
---
P
T
E
----
A
A
V
L
G
G
H
D
A
V
F
L
A
L
P
H
G
H
S
A
V
L
A
Q
Q
L
-
S
P
E
T
L
I
I
D
C
G
A
D
F
R
L
T
D
A
A
V
W
E
R
F
Y
G
S
S
H
A
-----
G
S
W
P
Y
G
L
P
E
L
PG
A
R
D
Q
L
R
G
T
R
R
I
A
V
P
G
C
Y
P
T
A
A
L
L
A
L
F
--
P
A
L
--
A
A
D
L
-
I
---
E
P
A
V
T
V
V
-
A
V
S
G
T
S
G
A
G
R
-
A
A
T
T
D
L
L
G
A
E
V
I
G
S
A
R
A
Y
N
I
A
G
V
H
R
H
T
P
E
I
A
Q
G
L
R
A
V
T
-
D
R
D
V
--
S
V
S
F
T
P
V
L
I
P
A
----
S
R
G
I
L
A
T
C
T
A
R
T
R
S
P
L
S
Q
--
L
R
A
A
Y
E
K
A
Y
H
A
E
P
F
I
Y
L
M
P
----
E
----
G
Q
L
P
R
T
G
--
A
V
I
G
S
N
A
A
H
I
A
V
A
V
D
-
E
D
-
A
Q
T
F
V
A
I
A
A
I
D
N
L
V
K
G
T
A
G
A
A
V
Q
S
M
N
L
A
L
G
W
P
E
T
D
G
L
S
V
V
G
V
A
P
4
PsiBlast_PDB
70.00
41%
11
- C1 -
-
2CVO
-
ARGC_ORYSJ
A:
[73-415]
-
V
R
I
A
V
L
G
A
S
G
Y
T
G
A
E
I
V
R
L
L
A
N
H
P
-----
Q
F
R
I
K
V
M
T
A
D
--
R
K
-
A
G
E
Q
F
G
S
V
F
P
HLITQDLP
N
L
V
A
V
K
D
A
D
F
S
---
N
V
------------
D
A
V
F
C
C
L
P
H
G
T
T
Q
E
I
I
K
G
L
-
P
Q
E
L
K
I
V
D
L
S
A
D
F
R
L
R
D
I
N
E
Y
A
E
W
Y
G
H
S
H
R
A
P
E
L
Q
Q
E
A
V
Y
G
L
T
E
V
--
L
R
N
E
I
R
N
A
R
L
V
A
N
P
G
C
Y
P
T
S
I
Q
L
P
L
V
P
L
I
K
A
----
K
L
-
I
---
K
V
S
N
I
I
I
D
A
K
S
G
V
S
G
A
G
R
-
G
A
K
E
A
N
L
Y
T
E
I
A
E
G
I
H
A
Y
G
I
K
G
-
H
R
H
V
P
E
I
E
Q
G
L
S
E
A
A
E
S
K
V
T
I
S
---
F
T
P
N
L
I
C
M
----
K
R
G
M
Q
S
T
M
F
V
E
M
A
P
G
V
T
A
N
D
L
Y
Q
H
L
K
S
T
Y
E
G
E
E
F
V
K
L
L
N
----
G
----
S
S
V
P
H
T
R
--
H
V
V
G
S
N
Y
C
F
M
N
V
-
F
E
-
D
R
I
P
G
R
A
I
I
I
S
V
I
D
N
L
V
K
G
A
S
G
Q
A
V
Q
N
L
N
L
M
M
G
L
P
E
N
T
G
L
Q
Y
Q
P
L
F
P