@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQU3: (2017-11-29 )
MTRTANEFLTPQAIKVEAVSGTSAKVILEPLERGFGHTLGNALRRILLSSLPGAAVVEVEIEGVEHEYSTLEGLQQDIVELLLNLKGLSIKLFDQNEAYLTLEKQGPGDITAADLRLPHNVEVVNPEHLIGTLSATGSLKMRLKVSQGRGYETSDSRFPEGETRPVGRLQLDASYSPIKRVSYTVENARVEQRTDLDKLVIDLETNGTVDPEEAIRKAATILQQQIAIFVDLQKDQTPVAQEPREEVDPILLRPVDDLELTVRSANCLKAENIYYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASKGLQLGMRLENWPPASLRMDDRFAYRSR
Atome Classification :
(27 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130..-.....140.......150...-...-.160.......170.......180.......190.......200.......210.......220.......230.....-..240.......250.......260.......270.......280.......290.......300.......310.......320.......330...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTRT
A
N
EFLTP
Q
A
I
K
V
E
AVSGTS
A
K
V
I
L
E
P
L
E
R
GF
G
H
T
L
G
N
A
L
R
R
I
L
L
SSLPG
A
A
V
V
E
V
E
I
EGVE
H
E
Y
S
T
L
E
G
L
Q
Q
D
I
V
E
L
L
L
NLKG
L
S
I
K
L
F
DQN
E
A
Y
L
T
L
EKQGPGD
I
T
A
ADLRLPHN
V
E
VV
N
P
E
H
L
I
G
T
LS-ATG
S
L
K
M
R
L
K
VSQGRGYETSD-SRF-PEGETRP
V
G
R
L
Q
LDASYSPI
K
R
V
S
Y
T
VENAR
V
E
Q
RTD
L
D
K
L
V
I
D
LETNGTV
D
P
E
E
A
I
R
K
A
A
T
I
L
Q
Q
Q
I
A
I
F
V
D
LQKDQT-PVAQE
P
R
E
EVD
P
I
L
LRPVDD
L
E
L
T
V
RSANCLKAE
N
I
Y
Y
I
G
D
L
V
Q
R
TE
V
E
L
L
KTPNLG
K
K
S
L
T
E
I
K
D
V
L
A
SK
G
L
Q
L
G
M
RLENWPPASLRMD
D
R
FAYRSR
4
PsiBlast_PDB
80.39
66%
-7
- C1 -
-
4JK2
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
3
PsiBlast_PDB
78.94
66%
-3
- C1 -
-
4JK1
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
8
PsiBlast_PDB
78.82
66%
-6
- C1 -
-
4KN7
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
15
PsiBlast_PDB
78.05
66%
-7
- C1 -
-
5EZK
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
7
PsiBlast_PDB
77.65
66%
-4
- C1 -
-
4KN4
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
6
PsiBlast_PDB
76.50
66%
-4
- C1 -
-
4KMU
-
RPOA_ECOLI
A:
[3-325]
--
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
13
PsiBlast_PDB
75.63
66%
-1
- C1 -
-
4YG2
-
RPOA_ECOLI
A:
[7-325]
------
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
10
PsiBlast_PDB
74.11
66%
-1
- C1 -
-
4YFK
-
RPOA_ECO24
A:
[7-325]
------
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
19
PsiBlast_PDB
73.19
66%
0
- C1 -
-
5UAQ
-
RPOA_ECOLI
A:
[7-325]
------
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
-----------
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
14
PsiBlast_PDB
70.69
66%
2
* C1 *
-
5BYH
-
RPOA_ECOLI
A:
[10-326]
---------
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
--------------
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
I
-----------
1
PsiBlast_PDB
69.11
66%
-5
- C1 -
-
3IYD
-
RPOA_ECOLI
A:
[2-326]
-
Q
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
-----
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
-
P
E
V
K
E
E
K
P
E
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
I
-----------
5
PsiBlast_PDB
63.58
66%
-37
- C1 -
-
4JKR
-
?
A:
[6-232]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
----------------------------------------------------------------------------------------------------------
80
HHSearch
62.59
61%
-36
- C1 -
-
1BDF
-
RPOA_ECOLI
B:
[6-233]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
A
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
----
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
---------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
62.01
60%
0
- C- -
-
4YLN
1
RPOA_ECOLI
H:
[13-240]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
---------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
62.01
60%
0
- C- -
-
4YLO
1
RPOA_ECOLI
H:
[13-240]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
---------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
62.01
60%
0
- C- -
-
4YLP
1
RPOA_ECOLI
H:
[13-240]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
---------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.42
66%
-31
- C1 -
-
4S20
-
RPOA_ECOLI
A:
[6-232]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
----------------------------------------------------------------------------------------------------------
78
HHSearch
59.48
42%
-89
- C1 -
-
5TW1
-
RPOA_MYCS2
B:
[6-233]
---------
R
P
T
L
-
S
E
E
T
V
A
E
N
R
S
R
F
V
I
E
P
L
E
P
G
F
G
Y
T
L
G
N
S
L
R
R
T
L
L
S
S
I
P
G
A
A
V
T
S
I
R
I
D
G
V
L
H
E
F
T
T
V
P
G
V
K
E
D
V
T
D
I
I
L
N
L
K
G
L
V
V
S
S
D
D
D
E
P
V
T
M
Y
L
R
K
Q
G
P
G
V
V
T
A
G
D
I
V
P
P
A
G
V
T
V
H
N
P
D
M
H
I
A
T
L
N
-
D
K
G
K
L
E
V
E
L
V
V
E
R
G
R
G
Y
V
P
A
V
-
Q
N
---
K
A
S
G
A
E
I
G
R
I
P
V
D
S
I
Y
S
P
V
L
K
V
T
Y
K
V
E
A
T
R
V
E
Q
R
T
D
F
D
K
L
I
I
D
V
E
T
K
N
S
I
S
P
R
D
A
L
A
S
A
G
G
T
L
V
E
L
F
G
L
A
R
E
L
N
A
D
S
E
H
I
E
------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
59.31
66%
-26
- C1 -
-
5UAH
-
RPOA_ECOLI
A:
[6-238]
-----
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
----------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
58.84
66%
-28
- C1 -
-
4YFN
-
RPOA_ECO24
A:
[1-235]
M
Q
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
-
T
R
I
H
S
E
E
D
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
-------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
49.48
90%
-193
- C1 -
-
3N4M
2
RPOA_ECOLI
B:
[4-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
---------------
72
PsiBlast_CBE
47.40
90%
-196
- C1 -
-
3N4M
2
C:
[5-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
---------------
75
PsiBlast_CBE
44.69
90%
-180
- C1 -
-
1LB2
2
RPOA_ECOLI
B:
[5-76]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
----------------
69
PsiBlast_CBE
43.87
90%
-176
- C1 -
-
5CIZ
2
B:
[4-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
---------------
71
PsiBlast_CBE
43.53
90%
-166
- C1 -
-
3N97
2
RPOA_ECOLI
B:
[5-79]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
70
PsiBlast_CBE
43.43
90%
-174
- C1 -
-
3N97
2
C:
[5-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
--------------
74
PsiBlast_CBE
37.40
90%
-160
- C1 -
-
1LB2
2
E:
[5-70]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
----------------------