@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VR18: (2017-11-30 )
MAEIDMNTMDTFHQMDKSHQGYITEFNDKSEFEQRINTAWRRAEPEAVEELLQAAAVSDDLDHKIYDLAFNLAHNLRERKTSSGKAGIVQGLLQEFSLSSQEGVALMCLAEALLRIPDTATRDLLIRDKINQGNWKEHVGQSSLMFVNAAAWGLMLTGKLMETPKQTSLSSVLTGLLARSGRGIIRKAVDVAMRMMGEQFVTGETIEEAVDHAKVLEDKGFRYSYDMLGEAALTDHDAERYFNDYTQAIHAIGKASNGKGVYDGPGISIKLSALHPRYQRAQIERVHKELYGKVFELARLAKQYNIGLNIDAEESERLEISLELLERLCFEPELANWKGIGFVIQAYQKRCFFVVDYIIDLAKRSQKRLMIRLVKGAYWDSEIKKAQIEGMDDYPVFTRKVHTDLSYIACAKKLLAAPEFIYPQFATHNAQTLATIYHLADPSKYYAGQYEFQCLHGMGEPLYEQVVGPRQQNKLGVPCRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADKTLKVEDLIQSPIYDIRNAAKLEGSVGLKHPSIPLPLDMYGTLRKNSKGYDLANDTPLAALDSTAQELRNRIWQSHPLLANTDSLEQGHSVAITNPAQNDEIVGYVQEADLKHVEIALTAAEQTQSEWSNTPKDQCAQYLKRAADLMESRIQELMVLLCRESGKTYANAIAEVREAVDFLRYYATQVENLPANTVIQPLGTVLCISPWNFPLAIFSGQIAAALVSGNCVIAKPAEQTPLIAAQAVQILWEAGIPHGAVQLLPGRGETVGAQLSQDSRIDGIMFTGSTEVAKILQKTVAKRLSENGQSIPLIAETGGQNAMIVDSSALTEQVVLDVVSSAFDSAGQRCSALRILCVQEDSAATVIKMLKGAMQQLIVGNPAILKTDIGPVIDDEAKQTIDQHIQKMKSKGYPVHQLMFGATSQTELDKGTFVVPTAIELPNLDDLQREVFGPVLHIITYKYGELEQLISRINAKGYGLTMGLHTRIDETIQTVIQHAEVGNLYINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYMYRLMQHCSNKVLATPFAVKNEQTIFEGFNREVYQSLQNWAKQHLPQANREIEPFGVGKFYELQGPTGESNQYIILPRHRVLSIADTEQDQLHQLLAIFAVGSQAAVMQNSPLLAKHKQTLPKDVLDAITTIKNITTDDFDAVLHHGNRKEIFSLQQEIASRSGAIVGITHVEPNESIPLERLVIERAISVNTAAAGGNASLMTMSE
Atome Classification :
(41 SA)
.........10........20....---....30........40........50........60........70........80........90........100.-......110.......120.......130.......140.......150.......160--........170.......180.......190.......200.......210.......220.......230.......240.......250.......--------------260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550...-....560.......570.......580..-.-....590.......600.......610.......620.......630......---.640.......650.......660.......670.......680.-......690......--------.700..-------------.-------------.-------------...-----------710---------..-------------.......720.......730.......740.......750.......760.......770.......780.......790.......800..-.....810.......820....--...830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950...--....---.960--.........970.......980.......990......-.1000......1010......1020......-1030......1040......1050......1060......1070...---..-.1080.....-----.1090......1100......1110......1120......1130......1140......1150......1160......1170......1180...-.-..1190......1200......1210......1220.------.....1230......1240......1250..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MAEID
M
N
T
M
D
T
F
H
Q
MDKSHQG
Y
I
TE---FN
D
K
S
E
F
E
Q
R
I
N
T
A
WRRA
E
P
E
A
V
E
E
L
L
Q
A
AAVSDDLD
H
K
I
Y
D
L
A
F
N
L
A
H
N
L
R
E
RKTSSG
K
A
G
I
V
Q
G
L
L
Q
EFSLSSQEG-
V
A
L
M
C
L
A
E
A
L
L
RIPDTATR
D
L
L
I
R
DKINQ
G
N
W
K
E
HVGQS
S
L
M
F
V
NAAA
W
G
L
M
L
T
G
K
L
M---ETPKQ
T
S
L
S
S
V
L
T
G
L
L
A
RSG
R
G
I
I
R
K
A
V
D
V
A
M
R
M
MGEQFVT
G
E
T
I
E
E
A
V
D
H
A
K
V
L
EDKG
F
R
Y
S
Y
D
MLGEAALT
D
H
D
A
E
R
Y
F
N
D
Y
T
Q
A
I
H
A
I
GKASNGK--------------GVYDGPG
I
S
I
K
L
SALHP
R
Y
Q
R
A
Q
I
E
R
V
H
K
E
L
Y
G
K
V
F
E
L
A
R
L
A
K
Q
YNI
G
L
N
IDAEES
E
R
L
E
I
S
L
E
L
L
E
R
LCFEPELANWK
G
I
G
F
V
I
Q
A
Y
Q
K
R
C
F
F
V
V
D
Y
I
I
D
L
A
K
R
S
Q
K
R
L
M
I
R
L
VKGAYW
D
S
E
I
K
K
A
QIEGMDDYP
V
F
T
R
K
VHTD
L
S
Y
I
A
C
A
K
K
L
LAAPEFIYPQFATHN
A
Q
T
L
A
T
I
YHLADPSKYYAG
Q
Y
E
F
Q
C
L
HGMG
E
P
L
Y
E
Q
VVGPRQQNKLGV
P
C
R
I
Y
A
PVG
N
H
E
T
L
L
A
Y
L
V
R
R
L
L
ENGA
N
T
S
F
V
N
R
I
A
DKT
L
K
V
E
D
L
I
QS
P
I
Y
D
I
R
N
A
A
KLEGSVGLKHPSIPL
P
L
D
M
Y
G
-
T
LRKNSKGYDLANDTP
L
A
A
L
D
S
T
A
Q
E
L
R
N
-
R
-
I
W
QSHPLLANTDSLEQGH
S
V
A
ITNPAQNDE
I
V
G
Y
V
Q
EADL
K
H
V
E
I
A
L
T
A
A
E
Q
T
---
Q
S
E
WSNT
P
K
D
Q
C
A
Q
Y
L
K
R
A
A
D
L
M
E
S
R
I
Q
E
L
M
V
L
L
C
RES
G
K
T
Y
A
N
A
-
I
A
E
V
R
E
A
V
D
F
L
R
Y
Y
A
--------
T
Q
V
ENL-------------P-------------A-------------NTV-----------I-----------QP-------------L
G
T
V
L
C
ISPWN
F
P
L
A
I
FSG
Q
I
A
A
A
LVSG
N
C
V
IAKPAEQTP
L
I
A
A
Q
A
V
Q
I
L
W
EAGIPH
G
A
V
Q
LLPGRGETVGAQLSQDSRI
D
G
I
M
FTG
S
T
E
V
A
-
K
I
L
Q
K
T
V
A
K
R
L
SENGQS
I
P
L
I
A
--ETGGQ
N
A
M
I
VD
S
S
A
L
T
E
Q
V
V
L
D
V
V
S
S
A
F
D
S
AGQR
C
S
A
L
R
I
L
C
VQED
S
A
A
T
V
I
K
M
L
K
G
A
M
Q
Q
L
IVGNP
A
I
L
KTDIGPVI
D
D
E
A
K
Q
T
I
D
Q
H
I
Q
K
M
K
SKGYP
V
H
Q
L
M
FGATSQTELDKG
T
F
V
V
P
TAI-ELP
N
--
L
D
D
L
---
Q
R
----
E
V
F
G
P
V
L
H
I
I
TYK
Y
G
E
L
E
Q
L
I
S
R
INAKGY
G
L
T
MG
L
H
T
R
-
I
D
E
T
I
Q
T
V
I
Q
HAEVG
N
L
Y
INRN
I
V
G
A
V
VGVQ-PFGGEGLSGTGPKAG
G
P
L
Y
M
Y
R
L
M
Q
H
CSNKVLAT
P
F
AVKN
E
Q
T
I
F
E
G---F
N
-
R
E
V
Y
Q
S
L
Q
N
W
-----
A
K
Q
HLPQANREIEPFGVG
K
F
Y
E
LQGPTGESN
Q
Y
I
I
L
PR
H
R
V
L
S
IADT
E
Q
D
Q
L
H
Q
L
L
A
I
F
AVGS
Q
A
A
VMQNSP
L
L
A
K
H
K
QTL
P
K
D
V
L
D
A
I
T
T
IKNIT
T
D
-
D
-
F
D
A
V
L
HHG
N
R
K
E
I
F
S
L
Q
Q
E
I
A
SRS
G
A
I
V
G
I
T
HVEPNE------SI
P
L
E
R
L
V
I
E
R
AISVNTAAAGGN
A
S
L
M
TMSE
1
PsiBlast_PDB
80.16
54%
-52
- C3 -
-
5KF7
7
?
A:
[30-1233]
-------------------------------
Q
S
T
L
R
R
A
I
T
A
A
Y
R
R
P
E
T
E
C
L
P
P
L
V
E
A
A
T
Q
S
K
E
I
R
D
A
A
A
S
T
A
R
K
L
I
E
A
L
R
G
K
----
G
----
V
E
G
L
V
Q
E
Y
S
L
S
S
Q
E
G
-
V
A
L
M
C
L
A
E
A
L
L
R
I
P
D
T
A
T
R
D
A
L
I
R
D
K
I
A
D
G
N
W
K
S
H
L
---
R
S
L
F
V
N
A
A
T
W
G
L
V
V
T
G
K
L
T
---
S
T
V
N
D
R
S
L
A
A
A
L
T
R
L
I
S
R
C
G
E
P
V
I
R
R
G
V
D
M
A
M
R
M
M
G
E
Q
F
V
T
G
E
T
I
R
E
A
L
K
R
S
K
E
L
E
E
K
G
F
S
Y
S
Y
D
M
L
G
E
A
A
T
T
A
A
D
A
E
R
Y
Y
R
D
Y
E
S
A
I
H
A
I
G
K
A
S
A
G
R
--------------
G
I
Y
E
G
P
G
I
S
I
K
L
S
A
L
H
P
R
Y
S
R
A
Q
A
A
R
V
M
G
E
L
L
P
R
V
K
A
L
A
L
L
A
K
N
Y
D
I
G
L
N
I
D
A
E
E
A
D
R
L
E
L
S
L
D
L
L
E
V
L
C
L
D
G
D
L
S
G
W
N
G
M
G
F
V
V
Q
A
Y
G
K
R
C
P
F
V
L
D
F
I
I
D
L
A
R
R
S
G
R
R
I
M
V
R
L
V
K
G
A
Y
W
D
A
E
I
K
R
A
Q
L
D
G
L
A
D
F
P
V
F
T
R
K
I
H
T
D
V
S
Y
I
A
C
A
A
K
L
L
A
A
T
D
V
V
F
P
Q
F
A
T
H
N
A
Q
T
L
A
A
I
Y
H
M
A
G
-
K
D
F
H
V
G
K
Y
E
F
Q
C
L
H
G
M
G
E
P
L
Y
E
E
V
V
G
---
R
G
K
L
D
R
P
C
R
I
Y
A
P
V
G
T
H
E
T
L
L
A
Y
L
V
R
R
L
L
E
N
G
A
N
S
S
F
V
H
R
I
N
D
P
K
V
S
I
D
E
L
I
A
D
P
V
E
V
V
R
A
M
P
----
V
V
G
A
K
H
D
R
I
A
L
P
A
E
L
F
G
-
D
A
R
T
N
S
A
G
L
D
L
S
N
E
E
T
L
A
S
L
T
E
A
L
R
E
S
A
A
-
M
-
K
W
T
A
L
P
Q
L
A
T
G
P
A
--
A
G
E
T
R
T
V
L
N
P
G
D
H
R
D
V
V
G
S
V
T
E
T
S
E
E
D
A
R
R
A
V
R
L
A
A
D
A
---
A
P
D
W
A
A
V
P
P
S
E
R
A
A
C
L
D
R
A
A
E
L
M
Q
A
R
M
P
T
L
L
G
L
I
I
R
E
A
G
K
S
A
L
N
A
-
I
A
E
V
R
E
A
I
D
F
L
R
Y
Y
A
--------
E
Q
T
R
R
T
LG-----------
P
-------------
G
-------------
H
-------------------------
G
P
-------------
L
G
P
I
V
C
I
S
P
W
N
F
P
L
A
I
F
T
G
Q
I
A
A
A
L
V
A
G
N
P
V
L
A
K
P
A
E
E
T
P
L
I
A
A
E
G
V
R
I
L
R
E
A
G
I
P
A
S
A
L
Q
L
L
P
G
D
G
R
-
V
G
A
A
L
V
A
A
A
E
T
A
G
V
M
F
T
G
S
T
E
V
A
-
R
L
I
Q
A
Q
L
A
D
R
L
S
P
A
G
R
P
I
P
L
I
A
--
E
T
G
G
Q
N
A
M
I
V
D
S
S
A
L
A
E
Q
V
V
G
D
V
I
T
S
A
F
D
S
A
G
Q
R
C
S
A
L
R
V
L
C
L
Q
E
D
V
A
D
R
I
L
T
M
L
K
G
A
L
H
E
L
H
I
G
R
T
D
R
L
S
V
D
V
G
P
V
I
T
S
E
A
K
D
N
I
E
K
H
I
E
R
M
R
G
L
G
R
K
V
E
Q
I
--
G
L
A
S
E
T
G
V
--
G
T
F
V
P
P
T
I
I
-
E
L
E
K
--
L
S
D
L
---
Q
R
----
E
V
F
G
P
V
L
H
V
I
R
Y
R
R
D
D
L
D
R
L
V
D
D
V
N
A
T
G
Y
G
L
T
F
G
L
H
T
R
-
L
D
E
T
I
A
H
V
T
S
R
I
K
A
G
N
L
Y
I
N
R
N
I
I
G
A
V
V
G
V
Q
-
P
F
G
G
R
G
L
S
G
T
G
P
K
A
G
G
P
L
Y
L
G
R
L
-------
V
T
T
A
P
V
P
P
Q
H
S
S
V
-------
H
T
-
D
P
V
L
L
D
F
A
K
W
L
D
G
K
G
A
R
A
E
A
E
A
A
R
N
A
G
S
S
S
A
L
G
L
D
L
E
L
P
G
P
V
G
E
R
N
L
Y
T
L
H
A
R
G
R
I
L
L
V
P
A
T
E
S
G
L
Y
H
Q
L
A
A
A
L
A
T
G
N
S
V
A
I
D
A
A
S
G
L
Q
A
S
L
K
N
-
L
P
Q
T
V
G
L
R
V
S
W
S
K
D
W
A
A
D
-
G
P
F
A
G
A
L
V
E
G
D
A
E
R
I
R
A
V
N
K
A
I
A
A
L
P
G
P
L
L
L
V
Q
A
A
S
S
G
E
I
A
R
N
P
D
A
Y
C
L
N
W
L
V
E
E
V
S
A
S
I
N
T
A
A
A
G
G
N
A
S
L
M
A
---
109
Fugue
79.04
49%
-43
- C3 -
-
4Q71
4
?
A:
[3-990]
M
P
N
I
P
-------------------------------
P
P
F
T
A
P
Y
A
P
D
D
A
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I
A
A
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L
L
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A
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H
L
S
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P
Q
E
A
R
I
H
R
T
A
T
R
L
I
E
A
I
R
K
R
L
------
G
G
V
E
D
M
L
R
E
F
A
L
S
T
K
E
G
-
L
A
L
M
V
L
A
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A
L
L
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V
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A
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A
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L
V
N
A
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A
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A
R
V
I
Q
P
G
-----
E
T
P
D
-----
G
T
I
G
R
L
V
K
R
L
G
A
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A
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R
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A
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A
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N
H
F
V
L
G
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E
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A
L
E
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--
P
G
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M
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G
A
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A
A
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A
R
R
Y
F
D
A
Y
A
S
A
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E
T
I
G
K
A
A
G
N
H
--------------
A
L
P
D
R
P
G
I
S
V
K
L
S
A
L
H
P
R
F
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A
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A
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V
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L
L
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L
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A
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A
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L
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L
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L
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A
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L
A
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L
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G
W
D
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F
G
L
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A
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Q
K
R
A
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A
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L
A
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L
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A
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L
L
A
L
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F
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N
A
L
T
V
A
T
V
L
E
M
A
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G
S
S
----
G
F
E
F
Q
R
L
H
G
M
G
E
A
L
Y
E
Q
L
A
K
D
H
A
----
D
I
A
Y
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Y
A
P
V
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L
L
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L
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A
N
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F
V
A
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A
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Y
R
V
P
V
P
A
L
L
Q
------
R
P
A
D
A
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V
R
P
Q
A
A
A
H
P
R
I
P
L
P
C
D
L
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A
-
P
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S
R
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V
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F
G
A
R
T
A
L
D
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L
L
T
D
V
K
A
---------------------------------------
E
I
A
D
A
T
P
D
Q
A
H
A
A
V
A
A
A
R
A
G
---
F
A
G
W
S
R
T
P
A
G
I
R
A
A
A
L
E
Q
A
A
H
L
L
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R
S
A
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A
L
L
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G
G
K
T
L
D
D
A
-
L
S
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L
R
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A
A
D
F
C
R
Y
Y
A
--------
A
Q
G
R
K
L
FG
S
E
T
A
M
P
G
P
T
G
E
S
-------------
N
-------------
A
L
T
-----------
M
-----------
R
G
-------------
R
G
V
F
V
A
I
S
P
W
N
F
P
L
A
I
F
L
G
Q
V
T
A
A
L
M
A
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N
S
V
V
A
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P
A
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A
L
L
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A
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L
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-
D
G
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-
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A
L
A
A
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---
D
G
P
I
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P
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--
E
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A
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A
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A
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Q
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A
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A
R
M
K
T
E
A
----
R
L
H
F
A
G
P
A
P
----
E
G
C
F
V
A
P
H
I
F
-
E
L
T
E
--
A
G
Q
L
---
T
E
----
E
V
F
G
P
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V
R
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-
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N
M
I
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A
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V
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-
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F
G
G
N
G
L
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G
T
G
P
K
A
G
G
P
H
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
R
F
A
T
E
Q
T
V
T
I
N
T
A
A
A
-----------
84
HHSearch
78.21
47%
-44
- C3 -
-
3HAZ
6
?
A:
[3-988]
-------------------------------
M
P
N
I
P
P
P
F
T
A
P
Y
A
P
D
D
A
E
I
A
A
R
L
L
P
A
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H
L
S
P
P
Q
E
A
R
I
H
R
T
A
T
R
L
I
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A
I
R
K
R
-----
R
L
G
G
V
E
D
M
L
R
E
F
A
L
S
T
K
E
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-
L
A
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A
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A
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L
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T
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A
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A
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A
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A
----
A
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---
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-
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-
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R
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A
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A
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A
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G
K
A
A
G
N
H
--------------
A
L
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A
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A
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V
L
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M
A
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G
----
S
S
G
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F
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L
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G
M
G
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A
L
Y
E
Q
L
A
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D
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A
----
D
I
A
Y
R
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Y
A
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H
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L
L
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Y
R
V
P
V
P
A
L
L
Q
R
P
A
D
A
I
V
R
P
------
Q
A
A
A
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P
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P
L
P
C
D
L
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A
-
P
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R
R
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R
G
V
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F
G
A
R
T
A
L
D
Q
L
L
T
D
V
K
-------------------------------
A
E
T
-
G
-
D
L
K
P
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A
D
A
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P
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A
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A
A
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A
A
A
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A
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---
F
A
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W
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A
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A
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A
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L
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L
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A
-
L
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L
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A
A
D
F
C
R
Y
Y
A
--------
A
Q
G
R
K
L
-------------
F
-------------
G
S
E
T
A
M
P
G
P
T
G
E
S
N
A
L
T
-----------
M
-----------
R
G
-------------
R
G
V
F
V
A
I
S
P
W
N
F
P
L
A
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L
G
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V
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A
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A
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L
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---
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G
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A
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A
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A
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A
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A
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A
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A
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L
L
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A
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M
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A
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A
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A
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A
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L
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A
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T
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A
R
L
H
F
A
G
P
A
--------
P
E
G
C
F
V
A
P
H
I
F
-
E
L
T
E
--
A
G
Q
L
---
T
E
----
E
V
F
G
P
I
L
H
V
V
R
Y
R
P
E
N
L
E
R
V
L
R
A
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T
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Y
G
L
T
L
G
V
H
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-
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D
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A
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Q
V
G
N
I
Y
V
N
R
N
M
I
G
A
V
V
G
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-
P
F
G
G
N
G
L
S
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G
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A
G
G
P
H
Y
L
A
R
F
A
T
E
Q
T
V
T
I
N
T
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
77.51
55%
-6
- C3 -
-
5KF7
7
?
A:
[16-1233]
-----------------
A
P
A
P
F
A
D
F
APP
V
R
P
Q
S
T
L
R
R
A
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T
A
A
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R
R
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C
L
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K
E
I
R
D
A
A
A
S
T
A
R
K
L
I
E
A
L
R
G
K
--------
G
V
E
G
L
V
Q
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Y
S
L
S
S
Q
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-
V
A
L
M
C
L
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A
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A
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A
L
I
R
D
K
I
A
D
G
N
W
K
S
H
L
---
R
S
L
F
V
N
A
A
T
W
G
L
V
V
T
G
K
L
T
---
S
T
V
N
D
R
S
L
A
A
A
L
T
R
L
I
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R
C
G
E
P
V
I
R
R
G
V
D
M
A
M
R
M
M
G
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F
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T
G
E
T
I
R
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A
L
K
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K
E
L
E
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K
G
F
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Y
S
Y
D
M
L
G
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A
A
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A
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A
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R
Y
Y
R
D
Y
E
S
A
I
H
A
I
G
K
A
S
A
G
R
--------------
G
I
Y
E
G
P
G
I
S
I
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L
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A
L
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G
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A
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V
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P
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A
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A
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A
A
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H
M
A
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C
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M
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L
Y
E
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V
V
G
R
G
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---
L
D
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C
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Y
A
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L
L
A
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L
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R
L
L
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A
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S
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A
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L
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A
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A
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M
-
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W
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L
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A
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V
G
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R
A
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A
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---
A
P
D
W
A
A
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P
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A
A
C
L
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A
A
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A
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M
P
T
L
L
G
L
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A
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A
L
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A
-
I
A
E
V
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A
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L
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Y
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A
--------
E
Q
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R
R
T
-------------
L
-------------
G
--------------
P
G
-----------
H
-----------
G
P
-------------
L
G
P
I
V
C
I
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P
W
N
F
P
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A
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Q
L
L
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-
V
G
A
A
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----
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G
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G
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F
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P
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I
I
-
E
L
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--
L
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L
---
Q
R
----
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F
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R
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D
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A
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N
A
-------
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---
2
PsiBlast_PDB
75.66
46%
-5
- C3 -
-
3HAZ
6
?
A:
[20-977]
------------------------------------------------
E
I
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-------------
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-------------
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F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------