@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VR34: (2017-11-30 )
MNIQALLLITSAIFISACSPYIVTANPNYSASKSDEKAEKIKNLFNEAHTTGVLVIQQGQTQQSYGNDLARASTEYVPASTFKMLNALIGLEHHKATTTEVFKWDGQKRLFPEWEKNMTLGDAMKASAIPVYQDLARRIGLELMSNEVKRIGYGNADIGTQVDNFWLVGPLKITPQQEAQFAYKLANKTLPFSQKVQDEVQSMLFIEEKNGNKIYAKSGWGWDVNPQVGWLTGWVVQPQGNIVAFSLNLEMKKGISSSVRKEITYRGLEQLGIL
Atome Classification :
(36 SA)
.........10........20........30.......--.40........50........60........70........80........90........-100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220-.........230.......240-.......250.......260.......270..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MN
I
Q
A
L
L
L
I
T
S
A
I
F
I
SACS
P
Y
I
V
TANPNYSASKS
D
E
K
A
--
E
K
I
K
N
L
F
N
EAHT
T
G
V
L
V
I
QQGQT
Q
Q
S
YG
N
D
L
A
R
ASTEYVP
A
S
T
F
K
M
L
N
A
L
IGLEHHKATT
T
-
E
V
F
KWDGQKRLF
P
E
W
EKNMTLGDAMKASA
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
N
E
V
K
R
IGYGNADIGTQVD
N
F
W
L
VG
P
L
KIT
P
Q
Q
E
A
Q
F
A
Y
K
LANKTLP
F
S
Q
K
V
Q
D
E
V
Q
S
M
L
F
I
EEKNG
N
K
I
Y
AKSGW---GWDVNPQ
V
G
W
L
T
G
W
V
VQPQG
N
I
-
V
A
F
S
L
N
L
E
M
K
KG
I
S
S
S
V
R
K
E
I
T
Y
R
G
L
E
Q
LGIL
1
PsiBlast_PDB
96.14
95%
-82
- C3 -
-
4ZDX
2
?
A:
[34-274]
---------------------------------
S
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
26
PsiBlast_CBE
95.83
95%
-81
- C3 -
-
5KZH
2
?
B:
[12-250]
-----------------------------------
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
24
PsiBlast_CBE
95.79
95%
-80
- C3 -
-
5KZH
1
?
D:
[11-250]
----------------------------------
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
25
PsiBlast_CBE
95.53
95%
-82
- C3 -
-
5KZH
1
?
C:
[10-250]
---------------------------------
S
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
3
PsiBlast_PDB
94.44
95%
-78
- C3 -
-
5L2F
2
?
A:
[12-250]
-----------------------------------
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
L
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
21
PsiBlast_CBE
94.30
95%
-79
- C3 -
-
5L2F
4
?
D:
[12-250]
-----------------------------------
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
L
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
2
PsiBlast_PDB
94.07
95%
-81
- C3 -
-
5KZH
3
?
A:
[11-250]
----------------------------------
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
23
PsiBlast_CBE
93.91
95%
-78
- C3 -
-
5L2F
2
?
B:
[11-250]
----------------------------------
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
L
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
22
PsiBlast_CBE
93.88
95%
-78
- C3 -
-
5L2F
4
?
C:
[11-250]
----------------------------------
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
L
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
G
N
I
-
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
162
HHSearch
91.49
95%
-57
- C3 -
-
5KZH
1
?
C:
[10-250]
---------------------------------
S
D
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
-
G
N
I
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
163
HHSearch
91.48
95%
-54
* C3 *
-
5KZH
2
?
B:
[12-250]
-----------------------------------
E
K
A
--
E
K
I
K
N
L
F
N
E
V
H
T
T
G
V
L
V
I
Q
Q
G
Q
T
Q
Q
S
Y
G
N
D
L
A
R
A
S
T
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
H
H
K
A
T
T
T
-
E
V
F
K
W
D
G
Q
K
R
L
F
P
E
W
E
K
D
M
T
L
G
D
A
M
K
A
S
A
I
P
V
Y
Q
D
L
A
R
R
I
G
L
E
L
M
S
K
E
V
K
R
V
G
Y
G
N
A
D
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
Q
Q
E
A
Q
F
A
Y
K
L
A
N
K
T
L
P
F
S
P
K
V
Q
D
E
V
Q
S
M
L
F
I
E
E
K
N
G
N
K
I
Y
A
K
S
G
W
---
G
W
D
V
D
P
Q
V
G
W
L
T
G
W
V
V
Q
P
Q
-
G
N
I
V
A
F
S
L
N
L
E
M
K
K
G
I
P
S
S
V
R
K
E
I
T
Y
K
S
L
E
Q
L
G
I
L
11
PsiBlast_PDB
89.71
65%
-84
- C3 -
-
5VFD
2
?
A:
[1-244]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
29
PsiBlast_CBE
88.67
62%
-100
- C3 -
-
4JF4
1
?
B:
[10-243]
------------------------------------------
I
H
Q
Y
F
D
E
K
N
T
S
G
V
L
V
I
Q
T
D
K
K
I
N
L
Y
G
N
A
L
S
R
A
N
T
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
Q
K
T
D
I
N
-
E
I
F
K
W
K
G
E
K
R
S
F
T
A
W
E
K
D
M
T
L
G
E
A
M
K
L
S
A
V
P
V
Y
Q
E
L
A
R
R
I
G
L
D
L
M
Q
K
E
V
K
R
I
G
F
G
N
A
E
I
G
Q
Q
V
D
N
F
W
L
V
G
P
L
K
V
T
P
I
Q
E
V
E
F
V
S
Q
L
A
H
T
Q
L
P
F
S
E
K
V
Q
A
N
V
K
N
M
L
L
L
E
E
S
N
G
Y
K
I
F
G
K
T
G
W
---
A
M
D
I
K
P
Q
V
G
W
L
T
G
W
V
E
Q
P
D
G
K
I
-
V
A
F
A
L
N
M
E
M
R
S
E
M
P
A
S
I
R
N
E
L
L
M
K
S
L
K
Q
L
N
I
I
10
PsiBlast_PDB
88.48
65%
-84
- C3 -
-
3G4P
-
?
A:
[32-275]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
7
PsiBlast_PDB
88.07
65%
-85
- C3 -
-
5TG7
2
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
-
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
14
PsiBlast_PDB
87.99
65%
-84
- C3 -
-
5TG6
1
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
-
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
16
PsiBlast_PDB
87.37
62%
-98
- C3 -
-
4JF4
2
?
A:
[10-243]
------------------------------------------
I
H
Q
Y
F
D
E
K
N
T
S
G
V
L
V
I
Q
T
D
K
K
I
N
L
Y
G
N
A
L
S
R
A
N
T
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
Q
K
T
D
I
N
-
E
I
F
K
W
K
G
E
K
R
S
F
T
A
W
E
K
D
M
T
L
G
E
A
M
K
L
S
A
V
P
V
Y
Q
E
L
A
R
R
I
G
L
D
L
M
Q
K
E
V
K
R
I
G
F
G
N
A
E
I
G
Q
Q
V
D
N
F
W
L
V
G
P
L
K
V
T
P
I
Q
E
V
E
F
V
S
Q
L
A
H
T
Q
L
P
F
S
E
K
V
Q
A
N
V
K
N
M
L
L
L
E
E
S
N
G
Y
K
I
F
G
K
T
G
W
---
A
M
D
I
K
P
Q
V
G
W
L
T
G
W
V
E
Q
P
D
G
K
I
-
V
A
F
A
L
N
M
E
M
R
S
E
M
P
A
S
I
R
N
E
L
L
M
K
S
L
K
Q
L
N
I
I
6
PsiBlast_PDB
87.25
65%
-80
- C3 -
-
5TG5
2
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
-
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
19
PsiBlast_PDB
86.85
61%
-95
- C3 -
-
4X55
1
?
A:
[20-253]
------------------------------------------
I
H
Q
Y
F
D
E
K
N
T
S
G
V
L
V
I
Q
T
D
K
K
I
N
L
Y
G
N
A
L
S
R
A
N
T
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
N
Q
K
T
D
I
N
-
E
I
F
K
W
K
G
E
K
R
S
F
T
A
W
E
K
D
M
T
L
G
E
A
M
K
L
S
A
V
P
V
Y
Q
E
L
A
R
R
I
G
L
D
L
M
Q
K
E
V
K
R
I
G
F
G
N
A
E
I
G
Q
Q
V
D
N
F
W
L
V
G
P
L
K
V
T
P
I
Q
E
V
E
F
V
S
Q
L
A
H
T
Q
L
P
F
S
E
K
V
Q
A
N
V
K
N
M
L
L
L
E
E
S
N
G
Y
K
I
F
G
K
T
G
W
---
A
M
D
I
K
S
Q
V
G
W
L
T
G
W
V
E
Q
P
D
G
K
I
-
V
A
F
A
L
N
M
E
M
R
S
E
M
P
A
S
I
R
N
E
L
L
M
K
S
L
K
Q
L
N
I
I
17
PsiBlast_PDB
86.78
62%
-100
- C3 -
-
4JF5
1
?
A:
[10-243]
------------------------------------------
I
H
Q
Y
F
D
E
K
N
T
S
G
V
L
V
I
Q
T
D
K
K
I
N
L
Y
G
N
A
L
S
R
A
N
T
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
Q
K
T
D
I
N
-
E
I
F
K
W
K
G
E
K
R
S
F
T
A
W
E
K
D
M
T
L
G
E
A
M
K
L
S
A
V
P
V
Y
Q
E
L
A
R
R
I
G
L
D
L
M
Q
K
E
V
K
R
I
G
F
G
N
A
E
I
G
Q
Q
V
D
N
F
W
L
V
G
P
L
K
V
T
P
I
Q
E
V
E
F
V
S
Q
L
A
H
T
Q
L
P
F
S
E
K
V
Q
A
N
V
K
N
M
L
L
L
E
E
S
N
G
Y
K
I
F
G
K
T
G
W
---
A
M
D
I
K
P
Q
V
G
W
L
T
G
W
V
E
Q
P
D
G
K
I
-
V
A
F
A
L
N
M
E
M
R
S
E
M
P
A
S
I
R
N
E
L
L
M
K
S
L
K
Q
L
N
I
I
8
PsiBlast_PDB
86.22
65%
-78
- C3 -
-
3PAE
1
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
13
PsiBlast_PDB
85.87
65%
-76
- C3 -
-
3PAG
1
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
D
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
12
PsiBlast_PDB
85.85
65%
-81
- C3 -
-
5TG4
4
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
-
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
-
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
-
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
28
PsiBlast_CBE
85.75
65%
-77
- C3 -
-
3PAG
1
?
B:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
D
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
27
PsiBlast_CBE
85.36
65%
-76
- C3 -
-
3PAE
1
?
B:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
5
PsiBlast_PDB
85.07
65%
-76
- C3 -
-
4WM9
7
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
--
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
9
PsiBlast_PDB
84.96
65%
-75
- C3 -
-
4F94
1
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
D
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
V
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
L
V
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
P
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
15
PsiBlast_PDB
82.24
65%
-67
- C3 -
-
4X53
1
?
A:
[2-245]
----------------------------
H
I
S
S
Q
Q
H
E
K
A
----
I
K
S
Y
F
D
E
A
Q
T
Q
G
V
I
I
I
K
E
G
K
N
L
S
T
Y
G
N
A
L
A
R
A
N
K
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
H
K
A
T
T
N
-
E
I
F
K
W
D
G
K
K
R
T
Y
P
M
W
E
K
D
M
T
L
G
E
A
M
A
L
S
A
D
P
V
Y
Q
E
L
A
R
R
T
G
L
E
L
M
Q
K
E
V
K
R
V
N
F
G
N
T
N
I
G
T
Q
V
D
N
F
W
--
G
P
L
K
I
T
P
V
Q
E
V
N
F
A
D
D
L
A
H
N
R
L
P
F
K
L
E
T
Q
E
E
V
K
K
M
L
L
I
K
E
V
N
G
S
K
I
Y
A
K
S
G
W
---
G
M
G
V
T
S
Q
V
G
W
L
T
G
W
V
E
Q
A
N
G
K
K
-
I
P
F
S
L
N
L
E
M
K
E
G
M
S
G
S
I
R
N
E
I
T
Y
K
S
L
E
N
L
G
I
I
18
PsiBlast_PDB
79.84
62%
-70
- C3 -
-
4K0W
5
?
A:
[10-244]
------------------------------------------
I
H
Q
Y
F
D
E
K
N
T
S
G
V
L
V
I
Q
T
D
K
K
I
N
L
Y
G
N
A
L
S
R
A
N
T
E
Y
V
P
A
S
T
F
K
M
L
N
A
L
I
G
L
E
N
Q
K
T
D
I
N
-
E
I
F
K
W
K
----------
K
D
M
T
L
G
E
A
M
K
L
S
A
V
P
V
Y
Q
E
L
A
R
R
I
G
L
D
L
M
Q
K
E
V
K
R
I
G
F
G
N
A
E
I
G
Q
Q
V
D
N
F
W
L
V
G
P
L
K
V
T
P
I
Q
E
V
E
F
V
S
Q
L
A
H
T
Q
L
P
F
S
E
K
V
Q
A
N
V
K
N
M
L
L
L
E
E
S
N
G
Y
K
I
F
G
K
T
G
W
A--
A
M
D
I
K
P
Q
V
G
W
L
T
G
W
V
E
Q
P
D
G
K
I
-
V
A
F
A
L
N
M
E
M
R
S
E
M
P
A
S
I
R
N
E
L
L
M
K
S
L
K
Q
L
N
I
I
31
PsiBlast_CBE
68.41
48%
35
- C3 -
-
4Y0U
1
?
C:
[39-277]
-------------------------------------
I
ID
Q
N
V
Q
A
L
F
N
E
I
S
A
D
A
V
F
V
T
Y
D
G
Q
N
I
K
K
Y
G
T
H
L
D
R
A
K
T
A
Y
I
P
A
S
T
F
-
I
A
N
A
L
I
G
L
E
N
H
K
A
T
S
T
-
E
I
F
K
W
D
G
K
P
R
F
F
K
A
W
D
K
D
F
T
L
G
E
A
M
Q
A
S
T
V
P
V
Y
Q
E
L
A
R
R
I
G
P
S
L
M
Q
S
E
L
Q
R
I
G
Y
G
N
M
Q
I
G
T
E
V
D
Q
F
W
L
K
G
P
L
T
I
T
P
I
Q
E
V
K
F
V
Y
D
L
A
Q
G
Q
L
P
F
K
P
E
V
Q
Q
Q
V
K
E
M
L
Y
V
E
R
R
G
E
N
R
L
Y
A
K
S
G
W
---
G
M
A
V
D
P
Q
V
G
W
Y
V
G
F
V
E
K
A
D
G
Q
V
-
V
A
F
A
L
N
M
Q
M
K
A
G
D
D
I
A
L
R
K
Q
L
S
L
D
V
L
D
K
L
G
V
F
30
PsiBlast_CBE
68.19
48%
37
- C3 -
-
4Y0U
1
?
D:
[37-277]
-----------------------------------
N
S
I
ID
Q
N
V
Q
A
L
F
N
E
I
S
A
D
A
V
F
V
T
Y
D
G
Q
N
I
K
K
Y
G
T
H
L
D
R
A
K
T
A
Y
I
P
A
S
T
F
-
I
A
N
A
L
I
G
L
E
N
H
K
A
T
S
T
-
E
I
F
K
W
D
G
K
P
R
F
F
K
A
W
D
K
D
F
T
L
G
E
A
M
Q
A
S
T
V
P
V
Y
Q
E
L
A
R
R
I
G
P
S
L
M
Q
S
E
L
Q
R
I
G
Y
G
N
M
Q
I
G
T
E
V
D
Q
F
W
L
K
G
P
L
T
I
T
P
I
Q
E
V
K
F
V
Y
D
L
A
Q
G
Q
L
P
F
K
P
E
V
Q
Q
Q
V
K
E
M
L
Y
V
E
R
R
G
E
N
R
L
Y
A
K
S
G
W
---
G
M
A
V
D
P
Q
V
G
W
Y
V
G
F
V
E
K
A
D
G
Q
V
-
V
A
F
A
L
N
M
Q
M
K
A
G
D
D
I
A
L
R
K
Q
L
S
L
D
V
L
D
K
L
G
V
F
32
PsiBlast_CBE
67.81
48%
37
- C3 -
-
4Y0U
1
?
B:
[38-277]
------------------------------------
S
I
I
D
Q
N
V
Q
A
L
F
N
E
I
S
A
D
A
V
F
V
T
Y
D
G
Q
N
I
K
K
Y
G
T
H
L
D
R
A
K
T
A
Y
I
P
A
S
T
F
-
I
A
N
A
L
I
G
L
E
N
H
K
A
T
S
T
-
E
I
F
K
W
D
G
K
P
R
F
F
K
A
W
D
K
D
F
T
L
G
E
A
M
Q
A
S
T
V
P
V
Y
Q
E
L
A
R
R
I
G
P
S
L
M
Q
S
E
L
Q
R
I
G
Y
G
N
M
Q
I
G
T
E
V
D
Q
F
W
L
K
G
P
L
T
I
T
P
I
Q
E
V
K
F
V
Y
D
L
A
Q
G
Q
L
P
F
K
P
E
V
Q
Q
Q
V
K
E
M
L
Y
V
E
R
R
G
E
N
R
L
Y
A
K
S
G
W
---
G
M
A
V
D
P
Q
V
G
W
Y
V
G
F
V
E
K
A
D
G
Q
V
-
V
A
F
A
L
N
M
Q
M
K
A
G
D
D
I
A
L
R
K
Q
L
S
L
D
V
L
D
K
L
G
V
F
33
PsiBlast_CBE
67.78
48%
38
- C3 -
-
4Y0U
1
?
A:
[38-277]
------------------------------------
S
I
I
D
Q
N
V
Q
A
L
F
N
E
I
S
A
D
A
V
F
V
T
Y
D
G
Q
N
I
K
K
Y
G
T
H
L
D
R
A
K
T
A
Y
I
P
A
S
T
F
-
I
A
N
A
L
I
G
L
E
N
H
K
A
T
S
T
-
E
I
F
K
W
D
G
K
P
R
F
F
K
A
W
D
K
D
F
T
L
G
E
A
M
Q
A
S
T
V
P
V
Y
Q
E
L
A
R
R
I
G
P
S
L
M
Q
S
E
L
Q
R
I
G
Y
G
N
M
Q
I
G
T
E
V
D
Q
F
W
L
K
G
P
L
T
I
T
P
I
Q
E
V
K
F
V
Y
D
L
A
Q
G
Q
L
P
F
K
P
E
V
Q
Q
Q
V
K
E
M
L
Y
V
E
R
R
G
E
N
R
L
Y
A
K
S
G
W
---
G
M
A
V
D
P
Q
V
G
W
Y
V
G
F
V
E
K
A
D
G
Q
V
-
V
A
F
A
L
N
M
Q
M
K
A
G
D
D
I
A
L
R
K
Q
L
S
L
D
V
L
D
K
L
G
V
F
73
PsiBlast_CBE
57.56
35%
28
- C3 -
-
4WZ5
1
BLO10_PSEAI
D:
[14-246]
----------------------------------------------
F
S
A
E
A
V
N
G
V
F
V
L
C
K
S
S
S
K
S
C
A
T
N
D
L
A
R
A
S
K
E
Y
L
P
A
S
T
F
K
I
P
N
A
I
I
G
L
E
T
G
V
I
K
N
E
H
Q
V
F
K
W
D
G
K
P
R
A
M
K
Q
W
E
R
D
L
T
L
R
G
A
I
Q
V
S
A
V
P
V
F
Q
Q
I
A
R
E
V
G
E
V
R
M
Q
K
Y
L
K
K
F
S
Y
G
N
Q
N
I
S
G
G
I
D
K
F
W
L
E
G
Q
L
R
I
S
A
V
N
Q
V
E
F
L
E
S
L
Y
L
N
K
L
S
A
S
K
E
N
Q
L
I
V
K
E
A
L
V
T
E
A
A
P
E
Y
L
V
H
S
K
T
G
F
SGV
G
T
E
S
N
P
G
V
A
W
W
V
G
W
-
V
E
K
E
T
E
V
-
Y
F
F
A
F
N
M
D
I
D
N
E
S
K
L
P
L
R
K
S
I
P
T
K
I
M
E
S
E
G
I
I
74
PsiBlast_CBE
56.89
35%
26
- C3 -
-
4WZ5
1
BLO10_PSEAI
C:
[14-246]
----------------------------------------------
F
S
A
E
A
V
N
G
V
F
V
L
C
K
S
S
S
K
S
C
A
T
N
D
L
A
R
A
S
K
E
Y
L
P
A
S
T
F
K
I
P
N
A
I
I
G
L
E
T
G
V
I
K
N
E
H
Q
V
F
K
W
D
G
K
P
R
A
M
K
Q
W
E
R
D
L
T
L
R
G
A
I
Q
V
S
A
V
P
V
F
Q
Q
I
A
R
E
V
G
E
V
R
M
Q
K
Y
L
K
K
F
S
Y
G
N
Q
N
I
S
G
G
I
D
K
F
W
L
E
G
Q
L
R
I
S
A
V
N
Q
V
E
F
L
E
S
L
Y
L
N
K
L
S
A
S
K
E
N
Q
L
I
V
K
E
A
L
V
T
E
A
A
P
E
Y
L
V
H
S
K
T
G
F
SGV
G
T
E
S
N
P
G
V
A
W
W
V
G
W
-
V
E
K
E
T
E
V
-
Y
F
F
A
F
N
M
D
I
D
N
E
S
K
L
P
L
R
K
S
I
P
T
K
I
M
E
S
E
G
I
I
70
PsiBlast_CBE
56.86
35%
33
- C3 -
-
5MOX
5
?
A:
[14-246]
----------------------------------------------
F
S
A
E
A
V
N
G
V
F
V
L
C
K
S
S
S
K
S
C
A
T
N
D
L
A
R
A
S
K
E
Y
L
P
A
S
T
F
K
I
P
N
A
I
I
G
L
E
T
G
V
I
K
N
E
H
Q
V
F
K
W
D
G
K
P
R
A
M
K
Q
W
E
R
D
L
T
L
R
G
A
I
Q
V
S
A
V
P
V
F
Q
Q
I
A
R
E
V
G
E
V
R
M
Q
K
Y
L
K
K
F
S
Y
G
N
Q
N
I
S
G
G
I
D
K
F
W
L
E
G
Q
L
R
I
S
A
V
N
Q
V
E
F
L
E
S
L
Y
L
N
K
L
S
A
S
K
E
N
Q
L
I
V
K
E
A
L
V
T
E
A
A
P
E
Y
L
V
H
S
K
T
G
F
SGV
G
T
E
S
N
P
G
V
A
W
W
V
G
W
-
V
E
K
E
T
E
V
-
Y
F
F
A
F
N
M
D
I
D
N
E
S
K
L
P
L
R
K
S
I
P
T
K
I
M
E
S
E
G
I
I