@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VR40: (2017-11-30 )
MTSSNTSRIAVQQIDPHELKAWIKAQALDLGFADCVSAKPDAQEQMPRFLEYLERGYHADMTYLEENLEKRADPTLLVPGTKSIICVRMNYLVESPKPRYVPFEPNSAITARYARGRDYHKVMRGRLKTLATRIREKVGDFESRPFADSAPIFEKSLAESAGMGWTGKHTLLIHKKSGSLFVLGELFTSLDLPFDEPATSHCGSCSACIDICPTQAIVEPYTLDARRCIAYLTIEYKGIIAEELRAGIGNRIFGCDDCQLICPWNSFAKTASIPDFNPRHGLDNISLLDIWQWDEATFLANTEGSPIRRTGYQSFKRNIAIGLGNAPYSKEIVDQLNKGKSLHDEIVNVHIDWAIEQQLNQL
Atome Classification :
(20 SA)
.........10........20.----.......30........40...-.-....50--------........60-......--...70........-80........90...-...-..100......-.110.......120.......130.-......140.....-.---.150.......160.......170........180.......190......----.200.......210...---....220---------------.........230.......240.......250....------...260.......270.......280.......290.......300.......310.......320.......330.......340........350---.......360-------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTSSNT
S
R
I
A
V
Q
QI
D
P
H
E
L
K
A
W
----
I
K
A
Q
A
LDL
G
F
A
D
CVSAKP
D
A
Q
E
-
Q
-
M
P
R
F
L
E
--------
Y
L
E
RGYHA
D
--
M
T
Y
L
E
E
--
N
L
E
KRAD
P
T
L
L
VP-GT
K
S
I
I
C
V
R
M
N
Y
L
VE-SPK-P
R
Y
VPFEPNS
A
-
I
T
A
RYARG
R
D
Y
H
K
V
M
R
G
R
L
K
T
L
A
T
R
-
I
R
E
K
VGDFESRPFA-D---SA
P
I
F
E
K
S
L
A
E
SAGMGWTG
K
H
T
-
L
L
I
HKKSG
S
L
F
V
L
G
E
L
F
T
SLDLPFDEPA----TSHCGS
C
S
A
C
I
DICPTQ---AIVEP-----------------YTL
D
A
R
R
C
I
A
Y
L
T
I
E
YK
G
I
I
A
E
E
L
R
A
G
IGNRIFGCD------D
C
Q
L
ICPWNSFAKTASIPDFNPRHGLDNI
S
L
L
D
I
WQWDE
A
T
F
L
ANTEGSP
I
R
R
T
G
Y
Q
S
F
K
R
N
I
A
I
GLGNAPY
S
K
E
I
V
D
Q
L
NKGK
S
-
L
H
D
E
I
V
N
V
H
I
D
---
W
A
I
E
Q
Q
L
NQL-------------------------------
62
HHSearch
77.50
27%
-2
- C5 -
-
5D08
4
QUEG_BACSU
B:
[30-373]
--------------
N
V
Y
Q
L
K
E
E
----
L
I
E
Y
A
K
S
I
G
V
D
K
I
G
F
T
T
A
D
T
F
D
-
S
L
K
D
R
L
I
L
--------
Q
E
S
L
G
Y
--
L
--
S
G
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
-
M
K
D
-
A
P
R
S
T
R
T
E
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
Q
-
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
D
P
E
I
A
K
P
L
L
K
P
L
L
A
I
S
N
R
E
F
K
E
K
F
G
H
V
S
G
S
W
R
G
K
K
P
I
Q
R
N
A
I
L
A
L
A
H
F
K
D
A
-
S
A
L
P
E
L
T
E
L
M
H
K
D
P
R
P
V
I
R
G
T
A
A
---
W
A
I
G
K
I
G
D
---------------------------------
51
Fugue
77.23
26%
-78
- C5 -
-
5D6S
3
?
A:
[28-399]
----------------
M
N
I
K
L
E
----
I
Q
K
M
A
K
E
I
G
I
S
K
I
G
F
T
T
A
D
D
F
D
-
Y
-
L
E
K
S
L
R
--------
L
G
V
E
E
G
R
T
T
---
G
F
E
H
K
--
N
I
E
E
R
I
Y
P
K
L
S
L
E
-
S
A
K
T
I
I
S
I
A
V
A
Y
P
-
H
-
K
L
P
-
Q
Q
P
Q
K
T
E
F
K
R
G
-
K
I
T
P
N
S
W
G
L
D
Y
H
Y
V
L
Q
D
K
L
K
R
L
A
K
G
-
I
E
K
L
T
E
N
F
E
Y
K
G
M
V
-
D
---
T
G
A
L
V
D
T
A
V
A
K
R
A
G
I
G
F
I
G
K
N
G
-
L
V
I
S
K
E
Y
G
S
Y
M
Y
L
G
E
L
I
T
N
L
E
I
E
P
D
Q
E
V
----
D
Y
G
C
G
D
C
R
R
C
L
D
A
C
P
T
S
---
C
L
I
G
D
-----------------
G
T
M
N
A
R
R
C
L
S
F
Q
T
Q
D
-
K
G
M
M
D
M
E
F
R
K
K
I
K
T
V
I
Y
G
C
D
------
I
C
Q
I
S
C
P
Y
N
R
G
I
D
N
----
P
L
D
I
D
P
D
L
A
M
P
E
L
L
P
F
L
E
L
T
N
K
S
F
K
E
T
F
G
M
I
A
G
S
W
R
G
K
N
I
L
Q
R
N
A
I
I
A
L
A
N
L
H
D
R
N
A
I
V
K
L
M
E
I
I
D
K
-
N
N
N
P
I
H
T
A
T
A
I
---
W
A
L
G
E
I
V
K
K
P
D
E
G
M
L
D
Y
M
R
G
LSPKD
E
H
S
Q
A
E
W
E
L
V
C
A
K
W
QI
63
HHSearch
76.99
27%
0
- C5 -
-
5D08
4
QUEG_BACSU
A:
[30-373]
--------------
N
V
Y
Q
L
K
E
E
----
L
I
E
Y
A
K
S
I
G
V
D
K
I
G
F
T
T
A
D
T
F
D
-
S
L
K
D
R
L
I
L
--------
Q
E
S
L
G
Y
--
L
--
S
G
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
-
M
K
D
-
A
P
R
S
T
R
T
E
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
Q
-
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
D
P
E
I
A
K
P
L
L
K
P
L
L
A
I
S
N
R
E
F
K
E
K
F
G
H
V
S
G
S
W
R
G
K
K
P
I
Q
R
N
A
I
L
A
L
A
H
F
K
D
A
-
S
A
L
P
E
L
T
E
L
M
H
K
D
P
R
P
V
I
R
G
T
A
A
---
W
A
I
G
K
I
G
D
---------------------------------
61
HHSearch
71.77
27%
10
- C5 -
-
5D6S
3
?
B:
[28-366]
--------------------
M
N
IKLE
I
Q
K
M
A
K
E
I
G
I
S
K
I
G
F
T
T
A
D
D
F
D
Y
L
-
E
K
S
L
R
L
--------
G
V
E
E
G
R
T
----
T
G
F
E
H
K
--
N
I
E
E
R
I
Y
P
K
L
S
L
E
-
S
A
K
T
I
I
S
I
A
V
A
Y
P
H
K
-
L
P
Q
-
Q
P
-
Q
K
T
E
F
K
R
G
-
K
I
T
P
N
S
W
G
L
D
Y
H
Y
V
L
Q
D
K
L
K
R
L
A
K
G
-
I
E
K
L
T
E
N
F
E
Y
K
G
M
V
-
D
---
T
G
A
L
V
D
T
A
V
A
K
R
A
G
I
G
F
I
G
K
N
G
-
L
V
I
S
K
E
Y
G
S
Y
M
Y
L
G
E
L
I
T
N
L
E
I
E
P
D
Q
E
V
----
D
Y
G
C
G
D
C
R
R
C
L
D
A
C
P
T
S
---
C
L
I
G
D
-----------------
G
T
M
N
A
R
R
C
L
S
F
Q
T
Q
-
D
K
G
M
M
D
M
E
F
R
K
K
I
K
T
V
I
Y
G
C
D
------
I
C
Q
I
S
C
P
Y
N
R
G
I
D
N
P
L
--
D
I
--
D
P
D
L
A
M
P
E
L
L
P
F
L
E
L
T
N
K
S
F
K
E
T
F
G
M
I
A
G
S
W
R
G
K
N
I
L
Q
R
N
A
I
I
A
L
A
N
L
H
D
R
N
A
I
V
K
L
M
E
I
I
D
K
-
N
N
N
P
I
H
T
A
T
A
I
---
W
A
L
G
E
I
V
K
---------------------------------
2
PsiBlast_PDB
67.29
35%
-13
- C5 -
-
5D0B
4
QUEG_BACSU
A:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
67.25
35%
-8
- C5 -
-
5D0A
4
QUEG_BACSU
D:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
-
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
66.61
35%
-11
* C5 *
-
5D0B
3
QUEG_BACSU
B:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
-
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
66.59
35%
-7
- C5 -
-
5D0A
6
QUEG_BACSU
A:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
-
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
66.54
35%
-7
- C5 -
-
5D0A
4
QUEG_BACSU
C:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
-
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
66.20
35%
-4
- C5 -
-
5D0A
5
QUEG_BACSU
B:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
-
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.38
35%
-14
- C5 -
-
5T8Y
3
QUEG_BACSU
A:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.20
35%
-7
- C5 -
-
5D08
4
QUEG_BACSU
A:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
-
M
K
D
A
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
V
-
D
---
T
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
64.91
35%
-15
- C5 -
-
5T8Y
4
QUEG_BACSU
B:
[77-291]
------------------------------------------------------------------------------
F
E
E
P
--
D
I
E
K
R
V
T
P
K
L
L
L
P
-
K
A
K
S
I
V
A
I
A
L
A
Y
P
S
R
M
K
D
A
-
P
R
S
T
R
T
E
-
R
R
G
-
I
F
C
R
A
S
W
G
K
D
Y
H
D
V
L
R
E
K
L
D
L
L
E
D
F
-
L
K
S
K
H
E
D
I
R
T
K
S
M
-------
G
E
L
S
D
R
A
V
A
E
R
A
G
I
G
F
S
A
K
N
C
-
M
I
T
T
P
E
Y
G
S
Y
V
Y
L
A
E
M
I
T
N
I
P
F
E
P
D
V
P
I
----
E
D
M
C
G
S
C
T
K
C
L
D
A
C
P
T
G
---
A
L
V
N
P
-----------------
G
Q
L
N
A
Q
R
C
I
S
F
L
T
-
Q
T
K
G
F
L
P
D
E
F
R
T
K
I
G
N
R
L
Y
G
C
D
------
T
C
Q
T
V
C
P
L
N
K
G
K
D
F
H
L
H
P
E
M
E
P
-----------------------------------------------------------------------------------------------------------------------
65
HHSearch
49.44
23%
15
- C5 -
-
4UR3
3
?
A:
[131-396]
------
D
R
R
P
P
D
T
T
D
P
V
E
L
T
N
Y
----
V
K
F
A
A
R
M
A
G
A
D
L
V
G
V
A
R
L
N
R
N
W
-----
V
Y
S
E
A
V
T
I
P
ADV
P
Y
E
Q
S
L
H
K
E
I
E
K
P
I
V
F
K
DV
P
L
P
I
E
T
D
D
E
L
I
I
P
N
T
C
E
N
V
I
V
A
G
I
A
M
N
R
E
-
M
M
Q
-
T
-----
A
P
N
---
S
M
A
C
A
T
T
A
F
C
Y
S
R
-
M
C
M
F
D
M
W
L
C
Q
F
-
I
R
Y
M
----
G
Y
Y
A
I
P
S
C
---
N
G
V
G
Q
S
V
A
F
A
V
E
A
G
L
G
Q
A
S
R
M
G
-
A
C
I
T
P
E
F
G
P
N
V
R
L
T
K
V
F
T
N
M
P
L
V
P
D
K
P
I
D
FG
V
T
E
F
C
E
T
C
K
K
C
A
R
E
C
P
S
K
---
A
I
T
E
G
P
R
T
FEGRSIHNQSGKLQ
W
Q
N
D
Y
N
K
C
L
G
Y
W
P
E
----------------
S
G
G
Y
C
G
------
V
C
V
A
V
C
P
F
T
K
G
N
---------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
47.07
23%
0
- C- -
-
4UQU
3
?
B:
[131-416]
------
D
R
R
P
P
D
T
T
D
P
V
E
L
T
N
Y
----
V
K
F
A
A
R
M
A
G
A
D
L
V
G
V
A
R
L
N
R
N
W
-----
V
Y
S
E
A
V
T
I
PADV
P
Y
E
Q
S
L
H
K
E
I
E
K
P
I
V
F
K
DV
P
L
P
I
E
T
D
D
E
L
I
I
P
N
T
C
E
N
V
I
V
A
G
I
A
M
N
R
E
-
M
M
Q
-
T
-----
A
P
N
---
S
M
A
C
A
T
T
A
F
C
Y
S
R
-
M
C
M
F
D
M
W
L
C
Q
F
-
I
R
Y
M
----
G
Y
Y
A
I
P
S
C
---
N
G
V
G
Q
S
V
A
F
A
V
E
A
G
L
G
Q
A
S
R
M
G
-
A
C
I
T
P
E
F
G
P
N
V
R
L
T
K
V
F
T
N
M
P
L
V
P
D
K
P
I
D
FG
V
T
E
F
C
E
T
C
K
K
C
A
R
E
C
P
S
K
---
A
I
T
E
G
P
R
T
FEGRSIHNQSGKLQ
W
Q
N
D
Y
N
K
C
L
G
Y
W
P
E
----------------
S
G
G
Y
C
G
------
V
C
V
A
V
C
P
F
T
K
G
N
---------------------------------------------------------------------------------------------------------------------------------
66
HHSearch
45.52
18%
-46
- C5 -
-
4RAS
3
?
A:
[345-575]
-----------
D
L
S
D
P
G
R
N
A
E
A
----
I
K
A
L
G
Y
Y
L
G
A
D
F
V
G
I
C
R
A
E
P
W
M
-----
Y
Y
A
S
------------
D
-------
E
V
---------
E
G
K
P
--
I
E
A
-
Y
H
D
Y
A
V
V
M
L
I
D
Q
G
Y
E
-
T
M
E
-
G
-----
A
S
G
D
D
-
W
I
S
A
S
Q
S
M
R
A
Y
M
R
-
G
A
E
I
A
G
V
M
A
A
H
-
C
R
R
M
----
G
Y
S
A
R
S
-
H
S
NA
H
S
E
V
I
H
N
P
A
I
L
M
A
G
L
G
E
V
S
R
I
G
D
T
L
L
N
P
F
I
G
P
R
S
K
S
I
V
F
T
T
D
L
P
M
S
V
D
R
P
I
D
FG
L
Q
D
F
C
N
Q
C
R
K
C
A
R
E
C
P
C
N
---
A
I
S
F
G
D
K
V
M
F
NGYEI-------
W
K
A
D
V
E
K
C
T
K
Y
R
V
T
Q
--------------
M
K
G
S
A
C
G
------
R
C
M
K
M
C
P
W
N
R
E
D
T
--------------------------------------------------------------------------------------------------------------------------------
52
Fugue
44.80
19%
-37
- C6 -
-
4MFL
3
?
A:
[23-345]
M
-
D
P
E
T
V
R
I
A
L
G
L
--
E
E
R
T
A
A
W
----
L
T
E
L
D
E
L
G
P
P
A
E
P
V
R
L
P
R
G
--
E
-
E
-
A
R
D
L
L
R
--------
R
L
E
V
P
E
L
D
A
--
E
E
I
V
A
A
--
A
P
D
P
D
R
D
P
A
L
W
W
L
-
L
E
R
T
H
H
A
I
V
R
H
M
G
D
H
-
R
A
K
-
P
R
G
G
P
P
L
P
Y
E
G
G
A
A
A
R
Y
F
H
V
Y
V
F
L
A
T
V
P
A
V
R
R
F
H
A
E
R
G
I
P
D
E
V
G
W
E
T
L
T
Q
L
G
-
E
---
L
V
A
I
H
R
R
K
Y
----
G
Q
G
G
M
N
M
Q
W
-
W
T
T
Y
H
L
R
G
I
L
Y
R
L
G
R
L
Q
F
S
L
A
T
G
K
D
G
------
T
P
H
L
G
L
A
------
V
P
E
W
GGP
L
L
P
K
A
-----------------
Y
D
E
S
L
H
R
A
R
P
F
F
D
R
H
F
P
E
H
G
A
R
------------------------
V
A
W
G
S
S
W
M
L
D
P
Q
L
E
E
Y
L
T
E
D
S
-------
N
I
I
Q
L
A
R
F
W
T
L
T
D
S
A
P
E
P
G
N
A
D
G
D
S
S
I
L
E
F
V
F
------
R
Y
N
G
Q
P
L
D
E
L
P
Q
R
S
S
-
L
E
R
A
V
I
A
H
L
K
A
G
R
H
W
H
M
R
T
G
F
V
K
L
P------------------------------
83
HHSearch
43.07
26%
-176
- C5 -
-
5EXE
2
OORD_MOOTA
E:
[258-306]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
A
C
T
E
C
Y
T
C
W
I
Y
C
P
D
S
---
C
I
T
R
T
EEG--------------
P
V
F
N
M
K
Y
C
K
------------------------
G
C
G
------
L
C
T
A
V
C
P
S
G
A
L
T
---------------------------------------------------------------------------------------------------------------------------------
76
HHSearch
37.89
34%
-77
- C5 -
-
1RGV
2
?
A:
[5-60]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
D
C
T
A
C
D
A
C
V
E
E
C
P
N
E
---
A
I
T
P
G
D
P
I
--------------
Y
V
I
D
P
T
K
C
S
------------------------
E
C
V
GAFDEP
Q
C
R
L
V
C
P
A
D
C
I
P
D
--------------------------------------------------------------------------------------------------------------------------------
80
HHSearch
37.73
33%
-102
- C5 -
-
5T5I
-
?
N:
[28-99]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
L
C
A
V
C
G
L
C
G
E
I
C
P
V
S
---
A
I
E
V
N
PTGAMVRTEQEKSK---
I
A
I
D
E
N
K
C
V
------------------------
L
C
G
------
M
C
S
S
I
C
P
F
Q
A
L
D
---------------------------------------------------------------------------------------------------------------------------------