@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VR46: (2017-11-30 )
MITQNKDILFRSPIMNKLMVYAYTGVVITMLFWGSAFNAMSYVIQYMPPLSAAAERFTIASLGLFILFAAIGKLSWAALRQNLVIYLIIGIIGIAGFNLGCFYGLQTTSAVNGALIMATTPLITLLLTILLDGEKLTLNKFIGVVFGLSGVLFVISHGHISTLLHLKIAIGDLFILLGGVSFCLANVLSRRYVKNATPLETTTFSMMFGALTLIILSVIFEHPSQAIAMAPITAHLAMGYVIICSTMIAYLFWFNGIQKLGAGRASIFFNFVPVFSMLVALLAGQSLNIWQLIGTALVMLGVMSSGGFIQIKRPALIAKPCTK
Atome Classification :
(20 SA)
------------------------------.........10........20..-......30-----.--.....-----------..40-----------.........50......----------..60.--------...-----...-.-----70.-----........80----------.........90........100.......110--.-......--..120-----.---.......130.-----......140..--..---------------------------------------...150...----....160------.........170-------------------.......----..---180..-----------------.....190.-----........200.-...------...210.----....------------.-----.220.---......230..-----..-...240--------------.--.------.------------......250...----....260-------....-..--..270..-----------.....--280........290----......--..300..---....------.310.......320.---------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------MITQNKD
I
L
FRS
P
I
M
N
K
L
M
V
Y
A
Y
-
T
G
V
V
I
T
M
L
-----
F
--WG
S
A
F
-----------
N
A
M
------------
S
Y
V
I
Q
YMP
P
L
S
A
A
A
E
R
F
----------
T
I
A
S
L
--------
G
L
F
-----
I
L
F
-
A
-----
A
-
I
-----
G
K
L
S
W
A
A
L
R-----------Q
N
L
V
I
Y
L
I
I
G
I
I
G
IAGFN
L
G
C
F
YGLQTTSA----V-N
G
A
L
I
M
--A
T
T
P
------
L
---
I
T
L
L
L
T
I
L
LDG-----EK
L
T
L
N
K
F
I
G
V
--
V
F
---------------------------------------
G
L
S
G
V
L
F
V
I----SHGH
I
--------
S
T
L
L
H
L
K
I
A
I
---------------------
G
D
L
F
I
L
L
----
G
G
---
V
S
F
C
L
-----------------
A
N
V
L
S
R
--
R
-----YVKNATPLE
T
T
T
-
F
S
M
------
M
F
G
A
L
T
L
----
I
I
L
S
------------
V
-----
I
F
EHP---SQ
A
I
A
MA
P
I
T
A
-----
H
L
-
A
M
G
Y
----------------
V
--
I
------
I
------------
C
S
T
M
I
A
Y
L
F
W
F
N
----
G
I
Q
K
LG--------AGR
A
-
S
I
--
F
F
N
F
V
P
V
-----------
F
S
M
L
V
--
A
-
L
LAGQS
L
N
I
W
Q
-----
L
I
G
T
A
L
--
V
M
L
G
VMS---SG
G
F
------
I
Q
I
KR
P
A
LIAKPCTK---------------------------------------------------------------------
16
Fugue
85.00
19%
-160
* C7 *
-
5I20
7
?
A:
[2-290]
---------------------------------------------
S
R
S
S
A
T
L
I
-
G
F
T
A
I
L
L
W
-----
S
--
T
L
A
L
A
-----------
T
S
S
------------
T
---
G
A
V
P
P
F
L
L
T
A
L
T
F
----------
T
I
G
G
A
--------
V
G
I
-----
A
A
G
-
L
-----
A
-
R
-----
G
V
---
S
V
L
R
-----------
Q
P
W
P
V
W
V
H
-
G
I
G
G
L
F
G
Y
H
F
F
Y
F
S
A
L
K
L
A
P
P
----
A
-
E
A
G
L
V
A
--
Y
L
W
P
------
L
---
L
I
V
L
F
S
A
F
L
P
G
-----
E
R
L
R
P
A
H
V
A
G
A
--
L
M
---------------------------------------
G
L
A
G
T
V
V
L
L
----
G
A
R
A
G
--------
G
F
G
F
A
P
E
Y
V
P
---------------------
G
Y
L
A
A
A
A
----
C
A
---
V
I
W
S
V
-----------------
Y
S
V
A
S
R
--
R
-----
F
A
R
------
V
P
T
-
E
V
V
------
A
G
F
C
L
A
T
----
A
A
L
S
------------
A
-----
L
C
H
I
L
---
F
E
P
S
V
W
P
V
G
S
E
-----
W
L
-
A
V
V
A
----------------
L
--
G
------
I
------------
G
P
V
G
I
A
F
Y
T
W
D
I
----
G
M
K
R
G
D
--------
V
R
L
L
-
G
V
--
L
S
Y
A
A
P
V
-----------
L
S
T
L
L
--
L
-
V
V
A
G
F
A
A
P
S
G
A
-----
L
A
I
A
C
A
--
L
I
V
G
G
A
A
---
V
A
T
L
------
L
A
R
R
L
E
S
-----------------------------------------------------------------------------
7
HHSearch
84.88
20%
-162
- C7 -
-
5I20
6
?
D:
[2-285]
-----------------------------------------------
S
R
S
S
A
T
-
L
I
G
F
T
A
I
L
-----
L
--
W
S
T
L
A
-----------
L
A
T
------------
S
-
S
T
G
A
V
P
P
F
L
L
T
A
L
T
F
----------
T
I
G
G
A
--------
V
G
I
-----
A
A
G
-
L
-----
A
-
R
-----
G
V
G
----
L
R
-----------
Q
P
W
-
P
V
W
V
H
G
I
G
G
L
F
G
Y
H
F
F
Y
F
S
A
L
K
L
A
P
P
----
A
-
E
A
G
L
V
A
--
Y
L
W
P
------
L
---
L
I
V
L
F
S
A
F
L
P
G
-----
E
R
L
R
P
A
H
V
A
G
A
--
L
M
---------------------------------------
G
L
A
G
T
V
V
L
L
----
G
A
-
A
G
--------
G
F
G
F
A
P
E
Y
V
P
---------------------
G
Y
L
A
A
A
A
----
C
A
---
V
I
W
S
V
-----------------
Y
S
V
A
S
R
--
R
-----
F
A
R
-
V
P
T
E
V
V
A
G
-
F
C
L
------
A
T
A
A
L
S
A
----
L
C
H
I
------------
L
-----
F
E
P
-
S
---
V
----
W
P
V
G
S
E
-----
W
L
-
A
V
V
A
----------------
L
--
G
------
I
------------
G
P
V
G
I
A
F
Y
T
W
D
I
----
G
M
K
R
G
D
--------
V
R
L
L
-
G
V
--
L
S
Y
A
A
P
V
-----------
L
S
T
L
L
--
L
V
V
A
G
F
A
A
P
S
G
A
L
-----
A
I
A
C
A
L
--
I
V
G
G
A
A
V
---
A
T
L
L
------
A
-----------------------------------------------------------------------------------
6
HHSearch
84.07
20%
-157
- C7 -
-
5I20
3
?
E:
[2-292]
-----------------------------------------------
S
R
S
S
A
T
-
L
I
G
F
T
A
I
L
-----
L
--
W
S
T
L
A
-----------
L
A
T
------------
S
-
S
T
G
A
V
P
P
F
L
L
T
A
L
T
F
----------
T
I
G
G
A
--------
V
G
I
-----
A
A
G
-
L
-----
A
-
R
-----
G
V
G
-
L
S
V
L
R
-----------
Q
P
W
-
P
V
W
V
H
G
I
G
G
L
F
G
Y
H
F
F
Y
F
S
A
L
K
L
A
P
P
----
A
-
E
A
G
L
V
A
--
Y
L
W
P
------
L
---
L
I
V
L
F
S
A
F
L
P
G
-----
E
R
L
R
P
A
H
V
A
G
A
--
L
M
---------------------------------------
G
L
A
G
T
V
V
L
L
----
G
A
R
A
G
--------
G
F
G
F
A
P
E
Y
V
P
---------------------
G
Y
L
A
A
A
A
----
C
A
---
V
I
W
S
V
-----------------
Y
S
V
A
S
R
--
R
-----
F
A
R
-
V
P
T
E
V
V
A
G
-
F
C
L
------
A
T
A
A
L
S
A
----
L
C
H
I
------------
L
-----
F
E
P
-
S
---
V
----
W
P
V
G
S
E
-----
W
L
-
A
V
V
A
----------------
L
--
G
------
I
------------
G
P
V
G
I
A
F
Y
T
W
D
I
----
G
M
K
R
G
D
--------
V
R
L
L
-
G
V
--
L
S
Y
A
A
P
V
-----------
L
S
T
L
L
--
L
V
V
A
G
F
A
A
P
S
G
A
L
-----
A
I
A
C
A
L
--
I
V
G
G
A
A
V
---
A
T
L
L
------
A
R
R
L
E
S
S
G
----------------------------------------------------------------------------
1
PsiBlast_PDB
72.31
24%
-157
- C7 -
-
5I20
5
?
A:
[61-259]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
-----------
Q
P
W
P
V
W
-
V
H
G
I
G
G
L
F
G
Y
H
F
F
Y
F
S
A
L
K
L
A
P
P
----
A
-
E
A
G
L
V
A
--
Y
L
W
P
------
L
---
L
I
V
L
F
S
A
F
L
P
G
-----
E
R
L
R
P
A
H
V
A
G
A
--
L
M
---------------------------------------
G
L
A
G
T
V
V
L
L
----
G
A
R
A
G
--------
G
F
G
F
A
P
E
Y
V
P
---------------------
G
Y
L
A
A
A
A
----
C
A
---
V
I
W
S
V
-----------------
Y
S
V
A
S
R
--
R
-----
F
A
R
--
V
P
T
E
V
V
A
G
F
C
L
------
A
T
A
A
L
S
-----
A
L
C
H
------------
I
-----
L
F
E
-
P
---
S
V
W
P
V
G
S
E
W
L
A
-----
V
V
-
A
L
G
---------------------------
I
------------
G
P
V
G
I
A
F
Y
T
W
D
I
----
G
M
K
R
G
D
--------
V
R
L
L
-
G
V
--
L
S
Y
A
A
P
V
-----------
L
S
T
L
L
--
L
-
V
V
A
G
----------------------------------------------------------------------------------------------------------------------------
17
Fugue
70.90
16%
-51
- C4 -
-
4K7J
3
?
A:
[26-375]
------------------------------
G
L
L
T
D
Y
G
N
A
S
A
S
P
W
M
K
K
L
Q
S
V
A
Q
G
S
G
E
T
F
R
I
L
-----
Q
--
I
G
D
S
H
-----------
T
A
G
------------
D
F
F
T
D
S
L
--
R
K
R
L
Q
K
T
W
----------
G
D
G
G
I
--------
G
-
W
-----
V
Y
P
-
A
-----
N
-
V
-----
K
G
Q
R
M
A
A
V
R
-----------
H
N
G
N
W
Q
S
L
T
S
R
N
N
T
G
D
F
P
L
G
---
G
I
L
A
H
T
G
----
S
-
G
G
S
M
T
L
--
T
A
S
D
GIASK
Q
R
---
V
S
L
F
A
K
P
L
L
A
E
-----
Q
T
L
T
V
N
G
N
T
V
S
--
A
N
---------------------------------------
G
-
G
G
W
Q
V
L
D
----
T
G
A
A
L
--------
P
L
T
I
H
T
E
M
P
W
---------------------
D
I
G
F
I
N
I
E
N
PA
G
G
---
I
T
V
S
A
-----------------
M
G
I
N
G
A
--
Q
-----
L
T
Q
W
S
K
W
R
A
D
R
M
-
N
D
L
------
A
Q
T
G
A
D
L
----
V
I
L
S
Y
G
T
N
E
A
F
NNNID
I
-----
A
D
T
E
Q
---
K
W
L
D
T
V
R
Q
I
R
D
-----
S
L
P
A
A
G
I
----------------
L
--
I
------
I
G
A
PESLKNTLGV
C
G
T
R
P
V
R
L
T
E
V
Q
----
Q
M
Q
R
R
V
--------
A
R
Q
G
Q
T
M
--
F
W
S
W
Q
N
A
-----------
M
G
G
I
C
--
S
-
M
K
N
W
L
N
Q
G
W
A
A
-----
K
D
G
V
H
F
--
S
A
K
G
Y
R
R
---
A
A
E
M
------
L
A
D
S
L
E
E
L
V
R
S
A
------------------------------------------------------------------------
19
Fugue
68.33
19%
-89
- C2 -
-
5HZD
-
?
A:
[3-511]
V
R
L
Y
S
C
DACPHAVFTT
H
A
A
L
L
A
H
A
E
E
HHAD
L
L
P
D
H
A
R
L
R
R
I
A
Q
K
L
N
P
V
W
N
R
A
L
-
N
A
R
R
N
T
I
T
-----
S
--
W
G
K
K
I
F
H
V
A
A
Q
R
DAG
E
S
K
M
------------
Q
E
A
H
R
A
R
A
Q
L
E
C
V
V
R
R
W
HDK
A
R
V
F
I
F
G
S
S
V
A
M
--------
G
V
W
DGT
A
D
I
D
F
-
A
-----
V
-
V
D
V
D
A
M
E
R
G
S
W
P
P
L
E
-----------
K
N
A
V
R
S
I
T
E
L
L
R
R
V
-
G
F
S
---
F
V
N
L
E
P
I
S
H
----
A
-
R
V
P
I
I
K
H
H
A
S
S
P
D-----
V
---
V
A
R
S
I
R
F
I
L
N
G
PAT
R
E
D
R
L
L
L
E
G
S
V
R
D
--
A
V
---------------------------------------
G
P
T
G
V
Q
Q
V
W
W
N
RT
S
D
M
M
S
--------
A
T
L
E
S
T
T
A
A
V
---------------------
R
A
A
M
C
S
P
----
A
L
---
A
S
A
S
L
-----------------
R
T
K
V
Q
P
--
A
-----
H
D
E
C
R
P
E
L
Y
N
I
D
-
F
D
L
------
S
F
R
A
F
G
I
R
N
S
T
L
L
R
K
------------
Y
-----
L
L
S
H
P
C
A
R
P
G
A
I
V
L
K
D
W
S
K
T
S
GVN
N
S
-
V
N
G
Y
---------------------------------------
F
T
S
Y
A
I
N
I
M
W
I
Y
----
Y
L
V
Q
K
G
YVPYVDPL
E
I
P
E
-
S
L
VN
Y
T
D
F
D
P
R
-----------
Y
T
P
M
I
DP
E
-
I
T
N
T
E
R
E
E
L
Y
K
-----
A
A
G
D
M
L
--
V
G
F
F
Y
F
Y
---
S
F
E
F
DWGHNV
I
S
L
N
R
P
G
I
T
T
K
R
M
L
G
WHVEDVRHPTRYE
L
C
I
E
D
PYEENLNLGRHIG
V
T
K
S
L
R
V
R
T
E
L
Y
R
G
L
L
S
L
L
K
ECVFAA------------
22
Fugue
62.62
19%
-93
- C4 -
-
4QNU
1
CMOB_ECOLI
A:
[1-323]
---------------------MIDF
G
N
F
Y
S
L
I
A
K
N
H
L
S
H
W
L
E
T
L
P
A
Q
I
A
N
W
Q
R
-
E
Q
Q
H
G
L
F
K
-----
Q
--
W
S
N
A
V
-----------
E
F
L
PEIKPYRLDLLH
S
V
T
A
E
S
E
E
P
L
S
A
G
Q
I
K
R
----------
I
E
T
L
M
R
N
L
MPWRK
G
P
F
-----
S
L
Y
G
V
-----
N
-
I
-----
D
T
E
W
R
S
D
W
K
-----------
W
D
R
V
L
P
H
L
S
D
L
T
G
R
T
I
L
D
V
G
C
G
S
G
Y
H
M
W
R
M
----
I
G
A
G
A
H
----------------------
L
A
V
G
I
D
P
-----
T
Q
L
F
L
C
Q
F
E
A
V
R
K
L
L
---------------------------------------
G
N
D
Q
R
A
H
L
L
----
P
L
G
-
I
--------
E
Q
L
P
A
L
K
-
A
F
---------------------
D
T
V
F
S
M
------
G
---
V
-----------------------------------
L
Y
H
R
R
S
P
L
E
H
---
L
W
Q
------
L
K
D
Q
L
V
N
E
G
E
-
L
V
L
E
------------
T
-----
L
V
I
D
G
---
D
E
N
T
V
L
V
P
G
D
R
-----
Y
A
-
Q
M
R
N
----------------
V
--
Y
------
F
------------
I
P
S
A
L
A
L
K
N
W
L
K
----
K
C
G
F
V
D
--------
I
R
I
A
-
D
V
--
S
V
T
T
T
E
E
-----------
Q
R
R
T
---
E
-
W
M
V
T
E
S
L
A
D
F
L
-----
D
P
H
D
P
G
--
K
T
V
E
--------
G
Y
------
P
A
P
K
R
A
V
L
I
A
R
K
P
-----------------------------------------------------------------------
20
Fugue
61.72
14%
-57
* C5 *
-
2G0D
-
NISC_LACLL
A:
[1-409]
---------------------KK
N
I
K
R
N
V
E
K
I
I
A
Q
W
D
E
R
T
R
K
D
F
G
E
L
T
L
S
T
G
L
-
P
G
I
I
L
M
L
A
-----
E
--
L
K
N
K
D
-----------
N
S
K
------------
I
Y
Q
K
K
I
D
N
Y
I
E
Y
I
V
S
K
L
----------
S
T
Y
G
L
LTGSLYS-
G
A
A
-----
G
I
A
-
L
-----
S
-
I
-----
L
H
L
R
E
D
D
E
K
-----------
Y
K
N
L
L
D
S
L
N
R
Y
I
E
Y
F
V
R
E
K
I
E
G
F
N
L
E
N
I
T
P
----
P
-
D
Y
D
V
I
E
--
G
L
S
G
------
I
---
L
S
Y
L
L
L
I
N
D
E
Q
-----
Y
D
D
L
K
I
L
I
I
N
F
--
L
S
N
L
T
KENNGLISLYIKSENQMS
Q
S
E
S
E
M
Y
PLGCLNMGLAH
G
L
A
G
V
G
C
I
L
----
A
Y
A
H
I
K
GYSN
E
A
S
L
S
A
L
Q
K
I
I
F
I
---------------------
Y
E
K
F
E
L
E
----
R
K
---
K
Q
F
L
W
-----------------
K
D
G
L
V
A
--
D
-----
E
L
K
K
E
K
V
I
R
E
A
S
-
F
I
R
D
A
WCYG
G
P
G
I
S
L
L
----
Y
L
Y
G
------------
G
-----
L
A
L
D
N
---
D
Y
F
V
D
K
A
E
K
I
L
-----
E
S
-
A
M
Q
R
----------------
K
--
L
GIDSYM
I
------------
C
H
G
Y
S
G
L
I
E
I
C
S
----
L
F
K
R
L
L
---------
N
T
K
-
K
F
--
D
S
Y
M
E
E
F
-----------
N
V
N
S
E
--
Q
-
I
L
E
E
Y
G
D
E
S
G
T
GFLEG
I
S
G
C
I
L
--
V
L
S
K
F
E
Y
---
S
I
N
F
------
T
Y
W
R
Q
A
L
L
L
F
D
D
F
L
K
GG-------------------------------------------------------------------
21
Fugue
61.06
18%
-87
- C5 -
-
4J1Q
1
A:
[20-445]
---------------------------------
H
M
E
R
L
M
L
E
P
V
W
E
K
Q
N
E
E
L
S
Y
-
T
E
H
I
I
V
L
F
ETE
R
S
V
--
T
D
S
I
A
-----------
S
H
M
KD----------
A
R
V
I
T
L
N
E
A
V
G
H
I
A
E
R
Y
----------
Q
C
Y
M
Q
--------
N
I
F
-----
E
L
L
-
Q
-----
S
K
V
-----
R
K
L
S
A
G
---------------
R
I
I
I
Q
A
I
V
P
L
E
K
E
K
Q
L
F
A
G
V
S
G
L
F
K
T
A
E
I
E
F
SK
L
-
T
A
Q
V
I
E
--
I
E
K
P
EE----
M
---
I
D
L
H
L
K
L
K
D
D
S
-----
R
R
-
P
F
D
K
Q
I
R
Y
--
E
------------------------------------------
A
G
Y
R
F
V
K
----
G
W
R
E
M
--------
V
D
T
L
H
M
P
W
R
D
---------------------
E
G
V
Y
L
I
T
----
G
G
AG
S
L
G
L
L
F
-----------------
A
K
E
I
A
N
--
R
T
GR
S
T
I
V
L
T
G
R
S
V
L
S
E
D
-
K
E
N
------
E
L
E
A
L
R
S
----
I
G
A
E
------------
V
-----
V
Y
R
E
A
DV-
S
D
Q
H
A
V
R
H
L
L
E
-----
E
I
-
K
E
R
Y
GTLNGIIHG
A
G
S
S
K
D
R
F
--
I
------
I
------------
H
K
T
N
E
E
F
Q
E
V
L
Q
PK
V
S
G
L
L
H
V
D
--------
E
C
S
K
-
D
F
--
P
L
D
F
F
I
F
-----------
F
S
S
V
S
--
G
-
C
L
G
N
A
-------------
G
Q
A
D
--
Y
A
A
A
N
S
F
---
M
D
A
F
------
A
E
Y
R
R
S
L
A
A
S
K
K
R
F
G
S
T
I
S
F
NWPLWEEGGMQVGAED
E
K
R
M
L
K
T
T
GMVPMP
T
D
S
G
L
K
A
F
Y
Q
G
I
V
S
DKP
Q
V
F
V
M
E
G
Q
L
Q
K
M
K
Q
K
LL
25
Fugue
52.70
16%
-96
* C4 *
-
5GNG
-
Y1552_HAEIN
A:
[1-214]
---------------------------------------------
M
K
T
K
F
Y
D
Y
-
Q
G
E
H
L
I
L
Y
-----
F
A
G
W
G
T
P
P
-----------
D
A
V
------------
N
H
L
I
--
L
P
E
N
H
D
L
L
I
C
Y
----------
D
Y
Q
D
L
--------
N
L
-------------------------
D
F
D
L
S
A
Y
R
-----------
H
I
R
L
V
A
W
S
M
G
V
W
V
A
E
R
V
L
Q
G
--
I
R
L
K
S
A
T
A
----
V
-
N
G
T
G
L
P
--
C
D
D
S
------
F
GIP
Y
A
I
F
K
G
T
L
E
N
L
-----
T
E
N
T
R
L
K
F
E
R
R
--
I
C
---------------------------------------
G
D
K
A
S
F
E
R
Y
----
Q
L
F
P
A
--------
R
P
F
D
E
I
H
Q
E
L
---------------------
T
A
L
F
A
M
I
----
Q
Q
---
D
K
R
I
D
-----------------
L
I
H
W
A
N
--
A
-----
W
V
S
S
R
D
K
I
F
T
P
A
-
N
Q
H
------
Q
Y
W
A
L
R
C
----
A
V
Q
E
------------
I
E
G
EHY
V
F
S
R
F
---
T
H
W
S
A
L
W
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
47.39
15%
-49
* C3 *
-
3DUZ
-
FUS_NPVAC
A:
[2-440]
------EHCNAQMKTGP
Y
K
I
K
N
L
DITPPK
E
T
L
Q
K
D
V
E
I
T
I
V
E
T
D
Y
N
E
N
V
I
I
G
Y
-
K
G
Y
Y
Q
A
Y
A
-----
Y
--
N
G
G
S
L
-----------
D
P
N
------------
T
R
V
E
E
T
M
K
T
L
N
V
G
K
E
D
L
----------
L
M
W
S
I
--------
R
Q
Q
-----
C
E
V
-
G
E
ELID
R
-
W
-----
G
S
D
S
D
D
C
F
R
DNEGRGQWVK
G
K
E
L
V
K
R
Q
N
N
N
H
F
A
H
H
T
C
N
K
S
W
R
C
G
I
S
T
S
K
M
----
Y
-
S
R
L
E
C
Q
--
D
D
T
D
------
E
---
C
Q
V
Y
I
---
L
D
A
-----
E
G
N
P
I
N
V
T
V
D
T
--
V
L
---------------------------------------
H
R
D
G
V
S
M
I
L
----
K
Q
K
S
T
--------
F
T
T
R
Q
I
K
A
A
C
L
L
I
K
DDKNNPESVT
R
E
H
C
L
I
D
N
D
I
Y
D
L
S
----
K
N
---
T
W
N
C
K
FN
R
C
I
K
RKRAKYTEGDT
A
T
K
G
D
L
--
M
-----
H
I
Q
E
E
L
M
Y
E
N
D
L
-
L
K
M
------
N
I
E
L
M
H
A
----
H
I
N
K
------------
L
-----
N
N
M
L
H
---
D
L
I
V
S
V
A
K
V
D
E
-----
R
L
-
I
G
N
L
----------------
M
N
N
S
------
V
------------
S
S
T
F
L
S
D
D
T
F
L
L
----
M
P
C
T
N
P
--------
P
A
H
T
-
S
N
--
C
Y
N
N
S
I
Y
KEGRWSSQ
C
I
D
F
S
N
Y
K
--
E
-
L
A
I
D
D
D
V
E
F
W
I
-----
P
T
I
G
N
T
--
T
Y
H
D
S
W
K
DA
S
G
W
S
F
------
I
A
Q
Q
K
S
N
L
I
T
T
M
E
N
T
K
F
GG-----------------------------------------------------------------
24
Fugue
45.01
12%
-171
- C3 -
-
3UM7
-
KCNK4_HUMAN
A:
[25-290]
-----------------------------------------
R
A
M
R
S
T
T
L
L
A
L
L
-
A
L
V
L
L
Y
L
V
-----
S
--
G
A
L
V
F
-----------
R
A
L
------------
E
-----
Q
P
H
E
Q
Q
A
Q
R
E
L
----------
G
E
V
R
E
--------
K
F
L
-----
R
A
H
-
P
-----
C
-
V
-----
S
D
Q
E
L
G
L
L
I
-----------
K
E
V
A
D
A
L
G
G
G
A
D
P
E
T
Q
S
T
S
A
W
--------
D
----
L
-
G
S
A
F
F
F
--
S
G
T
I
------
I
---
T
T
I
-------------------------------------------------------------------
G
Y
G
N
V
A
L
R
T
----
D
A
G
R
L
--------
F
C
I
F
Y
A
L
V
G
I
---------------------
P
L
F
G
I
L
L
----
A
G
---
V
G
D
R
L
-----------------
G
S
S
L
R
H
G
I
G
-----
H
I
E
A
I
F
L
K
W
H
P
E
-
L
V
R
------
V
L
S
A
M
L
F
----
L
L
I
G
------------
C
-----
L
L
F
V
L
---
T
P
T
F
V
F
C
Y
M
E
D
-----
W
----------------------------------------------
S
K
L
E
A
I
Y
F
V
I
V
----
T
L
T
T
V
G
--------
F
G
--------------------------
D
Y
V
A
--
G
-
A
D
P
R
Q
D
S
P
A
Y
Q
-----
P
L
V
W
F
W
--
I
L
L
G
L
A
Y
---
F
A
S
V
------
L
T
T
I
G
N
W
L
R
V
V
S
R
R
T
---------------------------------------------------------------------
9
HHSearch
32.70
11%
-158
- C7 -
-
5I20
2
?
E:
[147-287]
----------------------------------------------
P
E
Y
V
P
G
Y
-
L
A
A
A
A
C
A
V
-----
I
--
W
S
V
Y
S
-----------
V
A
S
------------
R
R
F
A
R
-
V
P
T
E
V
V
A
G
F
C
L
----------
A
T
A
A
L
--------
S
A
L
-----
C
H
I
-
L
-----
F
-
E
-----
P
S
--
V
W
P
V
G
-----------
S
E
W
L
A
V
V
A
L
G
I
G
P
V
G
I
A
F
Y
T
W
D
I
G
M
K
R
G
D
V
----
R
-
L
L
G
V
L
S
--
Y
A
A
P
------
V
---
L
S
T
L
L
L
V
V
A
G
F
-----
A
A
P
S
G
A
L
A
I
A
C
--
A
L
---------------------------------------
I
V
G
G
A
A
V
A
T
----
L
L
A
R
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
29.39
11%
-151
- C7 -
-
5I20
5
?
D:
[147-285]
----------------------------------------------
P
E
Y
V
P
G
Y
-
L
A
A
A
A
C
A
V
-----
I
--
W
S
V
Y
S
-----------
V
A
S
------------
R
R
F
A
R
-
V
P
T
E
V
V
A
G
F
C
L
----------
A
T
A
A
L
--------
S
A
L
-----
C
H
I
-
L
-----
F
-
E
-----
P
S
--
V
W
P
V
G
-----------
S
E
W
L
A
V
V
A
L
G
I
G
P
V
G
I
A
F
Y
T
W
D
I
G
M
K
R
G
D
V
----
R
-
L
L
G
V
L
S
--
Y
A
A
P
------
V
---
L
S
T
L
L
L
V
V
A
G
F
-----
A
A
P
S
G
A
L
A
I
A
C
--
A
L
---------------------------------------
I
V
G
G
A
A
V
A
T
----
L
L
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
28.48
31%
-
- C6 -
-
4IDU
-
NCAP_SBVBH
A:
[37-114]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---------------------------------------
G
V
A
R
V
F
F
-
L
----
N
Q
K
K
A
--------
K
M
V
L
H
-
K
T
A
Q
---------------------
P
S
V
D
L
T
F
----
G
G
---
V
K
F
T
V
-----------------
V
N
N
H
F
P
--
Q
-----
Y
V
S
N
P
V
P
D
N
A
I
T
-
L
H
R
------
M
S
G
Y
L
A
R
----
W
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
28.22
31%
-
* C6 *
-
4JNG
-
NCAP_SBVBH
A:
[37-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---------------------------------------
G
V
A
R
V
F
F
-
L
----
N
Q
K
K
A
--------
K
M
V
L
H
-
K
T
A
Q
---------------------
P
S
V
D
L
T
F
----
G
G
---
V
K
F
T
V
-----------------
V
N
N
H
F
P
--
Q
-----
Y
V
S
N
P
V
P
D
N
A
I
T
-
L
H
R
------
M
S
G
Y
L
A
R
----
W
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
28.22
31%
-
- C6 -
-
4IDX
-
NCAP_SBVBH
B:
[37-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---------------------------------------
G
V
A
R
V
F
F
-
L
----
N
Q
K
K
A
--------
K
M
V
L
H
-
K
T
A
Q
---------------------
P
S
V
D
L
T
F
----
G
G
---
V
K
F
T
V
-----------------
V
N
N
H
F
P
--
Q
-----
Y
V
S
N
P
V
P
D
N
A
I
T
-
L
H
R
------
M
S
G
Y
L
A
R
----
W
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
27.99
31%
-
- C6 -
-
3ZL9
-
NCAP_SBVBH
A:
[37-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---------------------------------------
G
V
A
R
V
F
F
-
L
----
N
Q
K
K
A
--------
K
M
V
L
H
-
K
T
A
Q
---------------------
P
S
V
D
L
T
F
----
G
G
---
V
K
F
T
V
-----------------
V
N
N
H
F
P
--
Q
-----
Y
V
S
N
P
V
P
D
N
A
I
T
-
L
H
R
------
M
S
G
Y
L
A
R
----
W
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
23.47
14%
-241
- C6 -
-
3RKO
-
?
F:
[132-168]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
F
G
P
Y
V
L
A
V
E
-----
L
A
S
M
L
L
LA
G
L
V
V
A
F
H
---
V
G
R
E
------
E
R
A
G
E
V
L
-----------------------------------------------------------------------------
15
HHSearch
22.98
16%
85
- C1 -
-
1B4I
-
KCNC4_HUMAN
A:
[6-24]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
V
---
S
S
Y
R
------
G
R
K
S
G
N
K
P
P
S
K
T
C
-----------------------------------------------------------------------