@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRA4: (2017-12-01 )
MSFDLSVIPHKNIVLAVTGGIAAYKSAILVRRLKDYGFDVRVVMTHGAQAFITPLTFQALSGNPVHTELLDPEAEAGMGHIELARWADLLLVAPASCDTLAKFANGLADDLLSTLFLATKAPVWVAPAMNQQMWAAKATQRNLQTLVEDGVHVIMPDAGEQACGDVGLGRMPEPEEIARQVAGYFHQAQRAIAEKFGLLAGKRVVITAGPTREAIDPVRYISNHSTGKMGFALAAACYAAGAKVTLIAGPVSLDTPNGVQRVNVASARQMLDVSMESLETGCDIFIATAAVADYRVAEVAEHKIKKAGDELNVSLVKNPDIVATIAAQEKRPFMVGFAAETQNVEEYAAGKLVAKKLDMIACNDVSRADIGFASDENAMTVFFAESYHMKKRELEKASKQEISQQLVEAISDALRRK
Atome Classification :
(20 SA)
.........10-........20........30........40........50........----60....---....70......--..--------80........90........100.......110......--.--120.......130.......140.......150.......160-.......-..170.......180.......190.......200.......210.......220.......230.......240.......250-.......260.......270.......280.......290.......300......-.310.......320.....-.-----.330-........340----.......350.......360.......370.......380.......390.......400.......410.....--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSF
D
L
S
VIPHK-
N
I
V
L
A
VTG
G
I
A
A
Y
K
S
A
I
L
V
R
R
L
K
DYGF
D
V
R
V
V
M
THGA
Q
A
F
I
T
P
L
T
F
QA----LSGNPV---HTELLDPEAEAG--MG--------
H
I
E
L
A
R
WA
D
L
L
L
VAPA
S
C
D
T
L
A
K
F
A
N
G
L
A
D
D
L
L
S
T
L
F
L
A--T--KA
P
V
W
VAPAMN
Q
Q
M
W
A
A
K
A
T
Q
R
N
L
Q
T
L
V
EDG
V
H
V
IMPDAGE---QACGDVG-LGRMP
E
P
E
E
I
A
R
Q
V
A
G
Y
F
H
Q
A
Q
R
A
I
A
E
K
F
G
LLAG
K
R
V
V
I
TAGPTREAI
D
P
V
R
Y
I
SNHSTG
K
M
G
F
A
L
A
A
A
C
Y
AAG
A
K
V
T
L
I
AGPVS-LDTPNG
V
Q
R
V
N
V
A
S
A
R
Q
M
L
D
V
S
M
E
S
L
ETGC
D
I
F
I
A
T
AAVAD
Y
R
V
A
E
V
A
E
H
K
I
K
KAG-DE
L
N
V
S
L
VKNP
D
I
V
A
T
IAA-Q-----EK-R-
P
F
M
V
G
F
AAETQ----
N
V
E
E
Y
AA
G
K
L
V
A
K
KL
D
M
I
ACNDVSRADIGFASDEN
A
M
T
V
F
FAESY
H
M
K
K
R
E
L
E
K
A
S
K
Q
E
I
S
Q
Q
L
V
E
A
I
S
D
A
LRRK--
21
PsiBlast_CBE
84.73
51%
-84
- C4 -
-
1U7Z
1
COABC_ECOLI
C:
[11-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
K
K
----
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
19
PsiBlast_CBE
83.80
51%
-89
- C4 -
-
1U80
1
COABC_ECOLI
C:
[11-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
-----
D
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
4
PsiBlast_PDB
83.67
51%
-91
- C4 -
-
1U80
2
COABC_ECOLI
A:
[11-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
K
K
----
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
2
PsiBlast_PDB
83.52
51%
-103
- C4 -
-
1U7W
2
COABC_ECOLI
A:
[11-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
------
D
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
-------------
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
20
PsiBlast_CBE
83.19
51%
-89
- C4 -
-
1U80
2
COABC_ECOLI
B:
[11-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
------
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
R
---
3
PsiBlast_PDB
82.67
51%
-83
- C4 -
-
1U7Z
2
COABC_ECOLI
A:
[11-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
-----
D
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
53
Fugue
82.58
51%
-79
- C4 -
-
1U7Z
2
COABC_ECOLI
A:
[3-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
D
L
K
H
L
N
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
-
Q
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
D
E
-----
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
-
L
-----
K
D
H
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
----
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
23
PsiBlast_CBE
82.24
51%
-113
- C4 -
-
1U7W
2
COABC_ECOLI
B:
[11-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
-------
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
--------------
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
R
---
22
PsiBlast_CBE
82.24
51%
-85
- C4 -
-
1U7Z
2
COABC_ECOLI
B:
[11-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
T
V
A
P
E
K
I
------
E
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
D
V
S
Q
P
T
Q
G
F
N
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
R
---
1
PsiBlast_PDB
82.05
51%
-104
- C4 -
-
1U7U
-
COABC_ECOLI
A:
[191-405]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
I
T
A
G
P
T
R
E
P
L
D
P
V
R
Y
I
S
D
H
S
S
G
K
M
G
F
A
I
A
A
A
A
A
R
R
G
A
N
V
T
L
V
S
G
P
V
S
-
L
P
T
P
P
F
V
K
R
V
D
V
M
T
A
L
E
M
E
A
A
V
N
A
S
V
Q
Q
Q
-
N
I
F
I
G
C
A
A
V
A
D
Y
R
A
A
--------------
L
T
I
K
M
V
K
N
P
D
I
V
A
G
V
A
A
L
K
-----
D
H
-
R
-
P
Y
V
V
G
F
A
A
E
T
N
----
N
V
E
E
Y
A
R
Q
K
R
I
R
K
N
L
D
L
I
C
A
N
----------
S
D
N
N
A
L
H
L
F
W
Q
D
G
D
K
V
L
P
L
E
R
K
E
L
L
G
Q
L
L
L
D
E
I
V
T
R
Y
D
E
K
N
R
----
5
PsiBlast_PDB
80.37
39%
-114
- C4 -
-
5INT
-
?
A:
[4-215]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
G
K
R
I
L
I
T
A
G
P
T
R
E
K
I
D
P
V
R
F
M
T
N
F
S
S
G
K
M
G
Y
A
I
A
E
V
A
V
N
L
G
A
E
V
I
L
V
S
G
P
T
A
-
L
N
P
P
L
H
V
T
T
V
Q
V
E
S
A
Q
D
M
L
E
A
V
I
Q
H
Y
Q
-
N
V
D
V
V
I
K
T
A
A
V
A
D
Y
R
P
K
Y
V
H
------------
V
I
E
L
E
R
T
V
D
I
L
K
T
L
G
E
-
M
-----
K
D
-
K
-
Q
L
L
I
G
F
A
A
E
T
T
----
N
V
E
E
Y
A
T
K
K
L
R
E
K
N
A
N
M
I
V
A
N
-----------
D
T
N
I
V
T
M
Y
R
K
D
G
E
V
I
---
E
L
P
L
L
T
K
K
E
V
A
R
E
I
L
K
Q
I
E
M
M
L
-----
55
Fugue
75.83
35%
-69
- C4 -
-
1E20
2
HAL3A_ARATH
A:
[18-202]
--------
R
K
P
-
R
V
L
L
A
A
S
G
S
V
A
A
I
K
F
G
N
L
C
H
C
F
T
E
-
W
A
E
V
R
A
V
V
T
K
S
S
L
H
F
L
D
K
L
S
L
P
Q
----
E
V
T
L
Y
T
---
D
E
D
E
W
S
S
W
N
K
I
G
DP
V
L
--------
H
I
E
L
R
R
W
A
D
V
L
V
I
A
P
L
S
A
N
T
L
G
K
I
A
G
G
L
C
D
N
L
L
T
C
I
I
R
A
WD
Y
--
T
K
P
L
F
V
A
P
A
M
N
T
L
M
W
N
N
P
F
T
E
R
H
L
L
S
L
D
E
L
G
I
T
L
I
P
P
I
K
K
R
---
L
A
C
G
D
Y
G
-
N
G
A
M
A
E
P
S
L
I
Y
S
T
V
R
L
F
W
E
S
Q
A
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
75.40
35%
-52
- C4 -
-
1E20
2
HAL3A_ARATH
A:
[18-197]
---------
R
K
P
R
V
L
L
A
A
S
G
S
V
A
A
I
K
F
G
N
L
C
H
C
F
T
E
W
A
-
E
V
R
A
V
V
T
K
S
S
L
H
F
L
D
K
L
S
L
----------
P
Q
---
E
V
T
L
Y
T
D
E
D
E
W
S
--
S
W
NKIGDPV
L
H
I
E
L
R
R
W
A
D
V
L
V
I
A
P
L
S
A
N
T
L
G
K
I
A
G
G
L
C
D
N
L
L
T
C
I
I
R
A
--
W
DY
T
K
P
L
F
V
A
P
A
M
N
T
L
M
W
N
N
P
F
T
E
R
H
L
L
S
L
D
E
L
G
I
T
L
I
P
P
I
K
K
R
---
L
A
C
G
D
Y
G
-
N
G
A
M
A
E
P
S
L
I
Y
S
T
V
R
L
F
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
75.32
35%
-68
- C4 -
-
1E20
2
HAL3A_ARATH
A:
[18-202]
--------
R
K
P
-
R
V
L
L
A
A
S
G
S
V
A
A
I
K
F
G
N
L
C
H
C
F
T
E
W
A
-
E
V
R
A
V
V
T
K
S
S
L
H
F
L
D
K
L
S
L
P
Q
----
E
V
-
T
L
Y
T
D
E
D
E
W
S
S
W
N
K
I
G
D
P
--
V
L
--------
H
I
E
L
R
R
W
A
D
V
L
V
I
A
P
L
S
A
N
T
L
G
K
I
A
G
G
L
C
D
N
L
L
T
C
I
I
R
A
WD
Y
--
T
K
P
L
F
V
A
P
A
M
N
T
L
M
W
N
N
P
F
T
E
R
H
L
L
S
L
D
E
L
G
I
T
L
I
P
P
I
K
K
R
---
L
A
C
G
D
Y
G
-
N
G
A
M
A
E
P
S
L
I
Y
S
T
V
R
L
F
W
E
S
Q
A
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.71
35%
-42
- C4 -
-
1MVN
2
HAL3A_ARATH
A:
[18-197]
---------
R
K
P
R
V
L
L
A
A
S
G
S
V
A
A
I
K
F
G
N
L
C
H
C
F
T
E
W
A
-
E
V
R
A
V
V
T
K
S
S
L
H
F
L
D
K
L
S
L
----------
P
Q
---
E
V
T
L
Y
T
D
E
D
E
W
S
--
S
W
NKIGDPV
L
H
I
E
L
R
R
W
A
D
V
L
V
I
A
P
L
S
A
N
T
L
G
K
I
A
G
G
L
C
D
N
L
L
T
C
I
I
R
A
--
W
DY
T
K
P
L
F
V
A
P
A
M
N
T
L
M
W
N
N
P
F
T
E
R
H
L
L
S
L
D
E
L
G
I
T
L
I
P
P
I
K
K
R
---
L
A
S
G
D
Y
G
-
N
G
A
M
A
E
P
S
L
I
Y
S
T
V
R
L
F
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
73.09
35%
-58
- C4 -
-
1E20
2
HAL3A_ARATH
A:
[18-198]
--------
R
K
P
-
R
V
L
L
A
A
S
G
S
V
A
A
I
K
F
G
N
L
C
H
C
F
T
E
-
W
A
E
V
R
A
V
V
T
K
S
S
L
H
F
L
D
K
L
S
L
P
Q
E
V
T
L
Y
T
D
E
D
E
---
W
S
S
-
W
N
K
I
-
G
D
P
--
V
L
--------
H
I
E
L
R
R
W
A
D
V
L
V
I
A
P
L
S
A
N
T
L
G
K
I
A
G
G
L
C
D
N
L
L
T
C
I
I
R
A
--
W
DY
T
K
P
L
F
V
A
P
A
M
N
T
L
M
W
N
N
P
F
T
E
R
H
L
L
S
L
D
E
L
G
I
T
L
I
P
P
I
K
K
R
---
L
A
C
G
D
Y
G
-
N
G
A
M
A
E
P
S
L
I
Y
S
T
V
R
L
F
W
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
72.05
27%
-144
- C4 -
-
5H75
2
?
D:
[6-190]
G
S
M
S
I
S
I
L
K
D
K
-
K
L
L
I
G
I
C
G
S
I
S
S
V
G
I
S
S
Y
L
L
Y
F
K
S
F
F
K
E
I
R
V
V
M
T
K
T
A
E
D
L
I
P
A
H
T
V
S
Y
----
F
C
D
-
H
V
---
Y
S
E
-
H
-------------------
H
V
E
I
G
R
W
A
D
I
Y
C
I
I
P
A
T
A
N
I
L
G
Q
T
A
N
G
V
A
M
N
L
V
A
T
T
V
L
A
--
H
--
P
H
N
T
I
F
F
P
N
M
N
D
L
M
W
N
K
T
V
V
S
R
N
I
E
Q
L
R
K
D
G
H
I
V
I
E
P
V
E
I
M
A
FE
I
A
T
G
T
R
K
P
N
R
G
L
I
T
P
D
K
A
L
L
A
I
E
Q
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
71.84
25%
-169
- C4 -
-
1G63
3
EPID_STAEP
E:
[1-174]
--------
M
Y
G
-
K
L
L
I
C
A
T
A
S
I
N
V
I
N
I
N
H
Y
I
V
E
L
K
Q
H
F
D
E
V
N
I
L
F
S
P
S
S
K
N
F
I
N
T
D
V
L
K
L
----
F
C
D
N
-
L
---
Y
D
E
I
-
K
---
D
P
L
--
L
N
--------
H
I
N
I
V
E
N
H
E
Y
I
L
V
L
P
A
S
A
N
T
I
N
K
I
A
N
G
I
C
D
N
L
L
T
T
V
C
L
T
--
G
--
Y
Q
K
L
F
I
F
P
N
M
N
I
R
M
W
G
N
P
F
L
Q
K
N
I
D
L
L
K
N
N
D
V
K
V
Y
S
P
D
M
N
-----------N
N
I
T
M
P
N
I
E
N
V
L
N
F
V
L
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
71.05
27%
-185
- C4 -
-
5H75
4
?
C:
[12-190]
------
I
L
K
D
K
-
K
L
L
I
G
I
C
G
S
I
S
S
V
G
I
S
S
Y
L
L
Y
F
K
S
F
F
K
E
I
R
V
V
M
T
K
T
A
E
D
L
I
P
A
H
T
V
S
Y
----
F
C
D
-
H
V
---
Y
S
E
-
H
---------------------
E
I
G
R
W
A
D
I
Y
C
I
I
P
A
T
A
N
I
L
G
Q
T
A
N
G
V
A
M
N
L
V
A
T
T
V
L
A
--
H
--
P
H
N
T
I
F
F
P
N
M
N
D
L
M
W
N
K
T
V
V
S
R
N
I
E
Q
L
R
K
D
G
H
I
V
I
E
P
V
E
I
-------------
R
G
L
I
T
P
D
K
A
L
L
A
I
E
Q
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
70.67
38%
-18
- C4 -
-
4QJI
1
?
B:
[7-234]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
H
D
M
A
G
V
K
A
L
V
T
A
G
G
T
R
E
P
L
D
P
V
R
F
I
G
N
R
S
S
G
K
Q
G
Y
A
V
A
R
V
L
A
Q
R
G
A
D
V
T
L
I
A
G
N
T
A
G
L
I
D
P
A
G
V
E
M
V
H
I
G
S
A
T
Q
L
R
D
A
V
S
K
-
H
A
P
D
A
N
V
L
V
M
A
A
A
V
A
D
F
R
P
A
H
V
A
A
A
K
I
K
K
G
A
S
E
P
S
S
I
D
L
V
R
N
D
D
V
L
A
G
A
V
R
-
A
R
A
D
GQ
L
P
-
N
M
R
A
I
V
G
F
A
A
E
T
G
D
ANG
D
V
L
F
H
A
R
A
K
L
E
R
K
G
C
D
L
L
V
V
N
--------------
D
G
W
L
L
S
A
D
G
-
T
E
-
S
A
-
L
E
H
G
S
K
T
L
M
A
T
R
I
V
D
S
I
A
A
F
L
K
S
---