@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRE1: (2017-12-02 )
MQFNPLYSSLNPKLFHIQQPSPLRGAKAGHFNLALAEELQWTDEEKQAWVEICSGQRTFSEFPPLAMVYAGHQFGQWARQLGDGRGLLIAQILNKKGQTIDLHLKGAGPTPYSRMGDGRAVLRSVIREYLAGHALNALGVASSHAVGFTSSTQGVQREKLEPGAMLLRTSECHIRLGHFEWINQYAPELLAEFTQKCIEWHYPECQQEEQPILAFAKAVIRNTAIMIAKWQLVGFAHGVMNTDNLNITGSTLDFGPYGFMERFRPNWINNHSDYQGRYTYQNQPSIAHWNLWTWLNNLIPLAEPEHKEQFKEALAACLEEFEPTFIEHYTTGLCQKMGLPHFHKDSTECGLSFLRILQAEQLDYTQSFIRLQNKEYKALRDDCLDIRQFDAFLTQYQNIREYQDIDELDANMQQVNPIYILRNHMAQRAIEVAERDDFSEVDRLFKLLNHPYTRQSDLEKPEDLGPLPSDVPDVAVSCSS
Atome Classification :
(20 SA)
.........10........20.----......-.30........40........50..-..-.....----60-........70---.........80----....-.....90.......-------------------.-100....-....110.......120.......130.......140-------..-.......150.-.--..-...160-------........--170.......180......----------.190.....-----..200..---.....--.210.......220...----....230..--.....240.......--------250---...-------......260-.---......270......-.280......-.290......----..300...--------.-----------...310.......320.....---.---------.330--.----.-...----...340.-.----------.....350.--------.--.....360.......370.......-380...-----..------..390.......400.......410.......--420.......430........440.......450.......460.......470.......480--------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MQFN
P
L
YSSLN
P
K
L
F
H
IQQPSP----LRGAKA-GHF
N
L
A
L
A
E
E
LQWT
D
E
E
K
Q
A
W
V
-
E
I
-CS-GQ
R
T
F
----SE-FPP
L
A
M
V
YA----GH
Q
F
G
Q
W
A
R
Q
-----LGDG-R
G
L
L
I
A
Q
I
LNKKG
Q
-------------------
T
-
I
-
D
L
H
L
K-GAGPTPYSRMG
D
G
R
A
V
L
R
S
V
I
R
E
Y
L
A
G
H
A
L
N
A
LGV---------AS-S
H
A
VGFTSSTQ-G--VQ-REKLE--------PG
A
M
L
L
RT--SE
C
H
I
RLG
H
F
E
W
I
N
Q
Y
A
P
E
----------
L
L
A
E
F
T
Q
K
C
-----
I
EW-HYP---
E
C
QQE--E
Q
P
I
L
A
F
A
K
A
V
I
RN
T
A
I
----
M
I
A
K
W
Q
L
V
G
--
F
AHGVMNTDN
L
N
I
TG--------S-----TLD-------FGP
Y
G
F
M
E
R-F---RPNWINNHSDY
Q
G
R
Y
-
T
YQNQPSIA
H
-
W
N
-
L
W
T
W
L
N
N
----LIPLAE
P
E
--------
H
-----------
K
E
Q
F
K
E
A
L
A
A
C
L
E
EF
E
P
T
F
I
E
---
H
---------
Y
T
T
---
G
----
L
-
C
Q
K----MGLPHFH-K----------D
S
T
E
C
G
L
S
F
--------
L
--
R
I
L
Q
A
E
Q
L
D
Y
T
Q
S
F
I
R
LQN
K
E
Y
K
A
L
-
R
D
D
C
L
D
-----
I
R
------
Q
F
D
A
F
L
T
Q
Y
Q
N
I
R
E
Y
Q
D
I
D
E
LDA
N
M
Q
QV
N
P
I
Y
--
I
L
R
N
H
M
A
Q
R
A
I
-
E
V
AERD
D
F
S
E
V
D
R
L
F
K
L
LNHPYTRQSDLEKPEDLGPLPSDVP
D
V
A
VSCSS----------------------------------------------------------------------------------------
35
Fugue
62.83
18%
55
- C4 -
-
4KYI
5
?
A:
[4-544]
---
G
S
E
I
S
K
T
E
A
G
Q
Y
S
V
S
A
P
E
H
K
G
L
V
L
S
G
G
G
A
K
G
I
S
Y
L
G
M
I
Q
A
L
Q
E
R
G
K
I
K
N
L
-----------
T
H
V
----
S
G
-
A
S
A
G
A
M
T
A
S
----
I
L
A
V
G
M
D
I
K
D
-----
I
K
K
L
I
E
G
L
D
I
T
K
L
L
D
N
S
G
V
GFRARG
D
R
F
R
N
I
L
D
V
I
Y
M
M
Q
-
M
-
K
K
H
L
E
-
S
V
Q
Q
P
I
P
P
E
Q
Q
M
N
Y
G
I
L
K
Q
K
I
A
L
Y
E
D
K
L
S
R
A
G
I
V
I
---------
N
N
V
D
D
I
I
N
L
T
K
S
V
K
-
D
--
L
E
-
K
L
D
K
A
LNSIPT
E
L
K
G
A
K
G
E
Q
L
--
E
N
P
R
L
T
L
G
D
L
G
R
L
R
E
L
L
P
E
ENKHLIKN
L
S
V
V
V
T
N
Q
T
K
H
-----
E
L
E
-
R
Y
S
---
E
D
T
T
P
--
Q
Q
S
I
A
Q
V
V
Q
W
S
G
A
H
P
V
L
----
F
V
P
G
R
N
A
K
G
E
Y
I
A
D
G
G
I
L
D
N
M
P
E
I
E
G
--------
L
-----
D
R
E
E
V
L
C
V
K
A
E
A
G
T
A
F
E
D
R
-
V
N
K
A
K
Q
S
A
M
E
A
I
S
W
F
K
A
R
M
-
D
S
L
V
T
S
S
V
L
N
R
E
K
-
V
Y
Y
N
I
D
N
----
M
I
Y
I
N
T
G
E
VTTTNTSP
T
-----------
P
E
Q
R
A
R
A
V
K
N
G
Y
D
Q
T
M
Q
L
L
D
S
---
H
---------
K
Q
T
FDH
P
----
L
-
M
A
I
----
L
Y
I
G
H
D
K
L
K
----------
D
A
L
I
D
E
K
S
E
--------
K
--
E
I
F
E
A
S
A
--
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
-
N
D
G
D
Y
S
S
V
Q
N
Y
L
D
------
Q
I
E
D
I
L
T
V
D
A
K
M
D
D
I
Q
K
E
K
A
F
A
L
C
I
K
Q
V
N
F
L
S
E
G
K
L
E
T
Y
L
N
K
V
E
A
-
E
A
K
A
A
A
E
P
S
W
A
T
K
I
L
N
L
L
W
A
P
I
E
W
V
V
S
L
F
K
----
G
P
A
Q
D
F
K
-------------------------------------------------------------------------------------------------
33
Fugue
57.78
19%
3
* C4 *
-
5IX1
1
MORC3_MOUSE
A:
[3-450]
---
G
I
R
L
S
A
L
C
P
K
F
L
H
T
N
S
T
S
H
------------
T
W
P
F
S
A
V
A
E
L
I
D
N
A
Y
D
P
D
V
N
A
K
Q
I
-
W
I
-
D
K
T
V
I
----
S
D
-
H
I
C
L
T
F
T
D
N
----
G
N
----------------
G
-
M
T
A
D
K
L
H
K
M
L
S
F
G
F
-------------------
S
-
D
-
K
V
T
M
N
-
G
H
V
P
V
G
L
----
Y
G
N
G
F
K
S
G
S
M
R
L
G
K
D
A
M
V
F
T
K
N
G
-----------
E
-
T
M
S
V
G
F
L
S
----------
Q
T
Y
L
E
--------
V
----
I
K
A
--
E
H
V
V
V
P
I
V
T
F
N
K
H
R
Q
M
I
N
L
----------
T
E
S
K
A
S
L
A
A
-----
I
L
E
-
H
S
L
-----
F
S
T
--
E
Q
K
L
L
A
E
L
N
A
I
M
G
K
K
G
T
----
R
I
I
I
W
N
L
R
S
--
Y
K
----
N
A
T
E
F
D
F
E
K
--------
D
-----
K
Y
D
-------
I
R
I
P
---
E
D
-
Y
---
K
K
Q
E
I
A
P
E
S
D
Y
-----------
S
L
R
A
-
Y
C
-
S
I
L
Y
L
K
P
R
M
Q
I
I
I
R
G
Q
K
V
K
--------
T
-----------
Q
L
V
S
K
S
L
A
Y
I
E
R
D
V
Y
R
P
K
F
L
T
R
T
V
R
---------
I
T
F
---
G
----
F
-
N
C
R
NKDH
Y
G
I
M
M
Y
H
-
K
NRLIKAYEKV
G
C
Q
N
M
G
V
G
V
--------
V
--
G
I
I
E
C
N
F
L
K
P
T
H
N
-----
K
Q
D
F
D
Y
T
-
N
E
Y
R
L
T
-----
I
L
------
A
L
G
E
K
L
N
D
Y
W
N
E
M
K
K
R
P
----
D
Q
T
W
V
Q
C
D
A
C
L
--
K
W
R
K
L
-----------
P
D
G
I
D
Q
L
P
E
K
W
Y
C
S
N
N
P
D
P
Q
F
R
N
C
E
V
P
E
E
----
P
E
D
E
-------------------------------------------------------------------------------------------------
28
Fugue
57.54
13%
31
- C3 -
-
5B86
-
TNAP2_MOUSE
A:
[17-600]
D
G
P
L
P
T
V
E
E
L
K
E
A
L
E
H
G
R
-------------------
L
E
V
A
W
Q
V
L
A
L
E
R
Q
L
E
A
A
A
-
A
A
-
G
G
M
S
N
E
E
L
V
W
R
Q
S
K
-
V
E
A
L
Y
V
L
L
C
----
D
Q
V
L
G
V
L
R
R
P
-----
L
E
A
A
-
P
E
R
L
S
Q
A
L
A
V
V
S
Q
E
-------------------
E
-
L
-
E
D
R
R
A
-
S
G
G
P
L
A
A
A
L
E
A
T
R
P
R
R
W
L
Q
R
W
R
G
V
V
A
E
V
A
A
E
R
L
D
A
---------
Q
P
-
G
R
S
E
A
E
S
R
F
L
H
M
G
--
R
T
M
K
E
D
L
E
--------
V
V
V
E
R
L
K
P
--
L
F
----
P
D
E
F
N
V
V
R
T
Y
A
E
S
----------
Y
H
Y
H
F
A
S
H
L
-----
C
A
L
A
Q
F
E
---
L
C
E
R
D
--
T
Y
L
L
L
L
W
V
Q
N
L
Y
P
N
D
I
L
NSPK
L
A
Q
E
L
Q
G
V
G
--
L
G
S
-
L
L
P
P
K
Q
I
R
L
L
E
--------
A
M
----
F
L
S
-------
N
E
V
T
S
V
K
Q
L
M
A
---
R
A
L
E
L
E
S
Q
R
W
T
Q
D
V
--
A
P
Q
S
L
D
G
H
C
H
-
S
E
-
L
A
I
D
I
L
Q
----
I
I
S
Q
G
Q
T
K
--------
A
E
N
I
T
S
D
V
G
M
Q
I
K
Q
L
L
L
V
E
L
A
A
L
L
R
S
Y
Q
R
A
F
D
E
---
F
L
E
KSKLLRN
Y
R
V
---
N
----
I
M
A
N
I
----
N
N
C
L
F
F
W
-
T
----------
S
V
E
Q
K
------------
W
--
Q
I
S
H
D
S
L
N
R
L
L
E
P
L
K
D
L
K
A
H
G
F
D
T
L
L
Q
S
L
F
L
D
-----
L
K
------
P
L
F
K
K
F
T
Q
T
R
W
A
N
P
V
E
T
L
E
E
I
I
T
T
V
S
S
S
L
P
E
F
--
S
E
L
Q
D
C
F
R
E
E
L
M
E
T
V
H
L
H
L
V
K
E
Y
--
I
I
R
L
C
K
R
R
L
V
L
K
T
A
E
Q
Q
Q
Q
L
A
R
H
I
L
A
N
A
D
A
I
Q
G
F
C
T
E
N
GSTATWLHR
A
L
P
M
I
A
E
I
I
R
LQD
S
S
A
I
K
I
E
V
A
T
Y
A
T
W
YPDFS
K
G
H
L
N
A
I
L
A
IKGNLPS
S
E
V
R
S
I
R
N
I
L
DINTGV
Q
E
P
P
RPLFSLIKVT
32
Fugue
55.54
14%
-53
* C3 *
-
5L3X
-
NELFD_HUMAN
B:
[1-405]
-------
G
E
I
T
S
V
S
T
A
C
Q
Q
L
E
V
----
F
S
R
V
L
R
-
T
S
L
A
T
I
L
D
G
G
E
E
N
L
E
K
N
L
P
E
F
A
-
K
M
V
C
H
-
G
E
H
T
Y
----
L
F
-
A
Q
A
M
M
S
V
L
A
----
Q
E
E
Q
G
G
S
A
V
R
-----
R
I
A
Q
-
E
V
Q
R
F
A
Q
E
K
G
H
D
A
S
-------------------
Q
-
I
-
T
L
A
L
G
-
T
A
A
S
---------
Y
P
R
A
C
Q
A
L
G
A
M
L
S
K
G
A
L
N
P
A
D
I
---------
T
V
-
L
F
K
M
-
F
T
S
M
D
P
--------------------
P
P
V
E
L
I
R
V
-------------------
P
A
----------
F
L
D
L
F
M
Q
S
L
-----
F
K
P
-
G
A
R
INQ
D
H
K
H
K
--
Y
I
H
I
L
A
Y
A
A
S
V
-----------
V
E
T
W
K
--
K
--
N
K
R
V
S
I
N
K
D
E
L
K
S
T
S
--------
K
-----
A
V
E
-------
T
V
H
N
L
C
C
N
E
-
N
---
A
S
E
L
V
A
E
L
S
T
L
Y
Q
C
I
-
R
F
----
P
V
V
A
-
M
G
-
V
L
K
W
V
D
W
----
T
V
S
---
E
P
--------
R
-----------
Y
F
Q
L
Q
P
V
H
L
A
L
L
D
E
I
S
T
C
H
--------------------------------------------------------------------------
Q
L
L
H
P
Q
V
L
Q
L
L
V
K
L
F
E
T
E
H
S
A
L
D
V
M
-
E
Q
L
E
L
K
-----
K
T
------
L
L
D
R
M
V
H
L
L
S
R
G
Y
V
L
P
V
V
S
Y
I
R
K
C
L
E
K
D
T
D
I
S
--
L
I
R
Y
F
V
T
E
V
L
D
-
V
I
A
P
P
Y
T
S
D
F
V
Q
L
F
L
P
I
L
E
N
D
S
I
A
D
P
V
T
E
F
I
A
H
C
K
S
N
F
I
M
V
N
------------------------------------------------------------------------------------------------
31
Fugue
50.34
18%
-35
- C3 -
-
5A5T
-
?
L:
[181-552]
---
Q
W
L
W
D
I
I
D
E
F
I
Y
Q
F
Q
S
F
S
Q
----
Y
R
C
K
T
A
-
K
K
S
----
E
E
E
I
D
F
L
R
S
N
P
K
I
W
-----------------
N
V
-
H
S
V
L
N
V
L
H
S
----
L
V
D
K
S
N
I
N
R
Q
-----
L
E
V
Y
-
T
S
-------------------------------------------
G
G
D
P
E
S
V
A
G
E
Y
---
G
R
H
S
L
Y
K
M
L
G
Y
F
S
L
V
G
L
L
R
---------
L
H
-
S
L
L
G
D
Y
Y
Q
A
I
K
-
V
--
L
E
-
N
I
E
L
N
--------
K
K
S
M
Y
S
R
V
---------------------------------------------------
P
---
E
C
Q
V
T
--
T
Y
Y
Y
V
G
F
A
Y
L
M
M
R
R
Y
Q
D
----
A
I
R
V
F
A
N
I
L
--
L
--
Y
I
Q
R
T
K
S
M
F
Q
R
T
--------
T
----------------
Y
K
Y
E
M
I
N
K
-
Q
---
N
E
Q
M
H
A
L
L
A
I
A
L
T
M
Y
-
P
M
R
I
D
E
S
I
-
H
-
L
Q
-
L
R
E
K
Y
G
D
----
K
M
L
R
M
Q
K
G
--------
D
-----------
P
Q
V
Y
E
E
L
F
S
Y
S
C
P
K
F
L
S
P
V
V
P
---
N
---------
Y
D
S
---
V
----
H
-----------
P
N
Y
H
-
K
----------
E
P
F
L
Q
Q
L
K
V
--------
F
SD
E
V
Q
Q
Q
A
Q
L
S
T
I
R
S
F
L
K
L
Y
T
T
M
P
V
A
K
-
L
A
G
F
L
D
-----
L
T
EQEFRI
Q
L
L
V
F
K
H
K
M
K
N
L
V
W
T
S
G
I
S
A
L
D
G
E
F
Q
S
A
S
E
V
-----
D
F
Y
I
D
K
D
M
I
-
H
I
A
D
T
K
V
A
R
R
Y
G
D
F
F
I
R
Q
I
H
K
F
E
E
------------------------------------------------------------------------------------------------------------------
36
Fugue
48.70
18%
13
- C1 -
-
1ZY7
1
RED1_HUMAN
A:
[8-402]
----------------
S
R
Q
P
I
P
----
S
E
G
L
Q
L
--
H
L
P
Q
V
L
A
D
A
V
S
--
R
L
V
L
G
K
F
G
-
D
L
-
T
D
-
N
F
S
S
P
----
H
A
R
R
K
V
L
A
G
V
V
M
----
T
T
--
G
T
D
V
K
D
AKVI
S
V
S
T
G
-
T
K
C
I
N
G
E
Y
M
S
D
R
G
L
-------------------
A
-
L
N
D
C
H
----------
A
E
I
I
S
R
R
S
L
L
R
-
F
L
Y
T
Q
L
E
L
Y
L
N
N
K
D
D
Q
---------
K
R
-
S
I
---
F
Q
K
S
E
R
-
G
G
F
R
L
-
K
E
N
V
Q
--------
F
H
L
Y
I
S
T
S
--
P
C
G
D
A
R
I
----
F
K
A
R
G
Q
L
R
----------
T
K
I
E
S
G
E
G
T
-----
I
P
V
-
R
S
N
---
A
S
I
Q
T
--
W
D
G
V
L
Q
G
E
R
L
L
T
M
S
C
S
D
----
K
I
A
R
W
N
V
V
G
--
I
Q
G
S
L
L
S
I
F
V
E
P
I
Y
F
--------
S
-----
S
I
I
-------
L
G
S
----------------
L
Y
H
G
D
H
L
S
R
A
-
M
Y
Q
R
I
S
N
I
E
D
-
L
P
P
L
Y
T
L
N
K
P
----
L
L
S
G
I
S
N
A
--------
E
-----------
A
R
Q
P
G
K
A
---------
P
N
F
S
V
---
N
---------
W
T
V
---
G
--------------------------------
D
S
---------------------
A
I
E
V
I
N
A
T
T
G
----
K
D
E
L
G
R
A
S
-
R
-----------
L
------
C
K
H
A
L
Y
C
R
W
M
R
V
H
G
K
V
P
S
H
L
L
R
S
K
I
T
K
P
N
V
Y
H
--
E
S
K
L
----------
A
A
K
E
Y
Q
A
A
K
A
R
L
F
T
A
F
I
K
A
G
L
G
-
A
W
V
E
K
P
T
E
Q
D
Q
F
S
L
T
--------------------------------------------------------------------------------------------------
34
Fugue
48.18
15%
18
- C2 -
-
5DIY
1
?
B:
[2-473]
------------------
E
Y
F
R
----
Y
R
G
I
I
E
-
G
F
Y
G
K
P
------
W
E
H
Q
E
R
L
D
M
F
-
E
F
-
M
Q
-
A
N
-----------
N
L
N
A
Y
I
Y
A
PKQD
L
Y
H
R
E
L
W
R
E
P
-----
Y
K
E
E
-
Q
L
Q
L
F
K
E
L
I
E
K
A
G
S
-------------------
C
G
I
-
N
F
T
F
A
I
S
P
G
L
S
L
V
Y
S
S
E
E
E
L
E
T
L
I
R
K
I
T
P
F
L
E
-
M
G
V
H
S
I
G
I
FFDNVPFDL
I
H
-
E
E
D
R
N
S
Y
S
N
L
A
-
E
--
A
Q
-
A
D
F
L
T
--------
R
V
L
Q
R
L
E
S
TI
S
T
P
Q
I
I
M
C
P
T
F
Y
C
N
D
P
N
L
E
----------
Y
L
R
I
L
G
Q
R
L
PKNID
V
F
W
-
T
G
P
N--
V
C
S
H
E
IT
T
S
H
M
Q
E
V
Q
K
S
L
Q
R
P
A
T
L
----
W
D
N
----------
Y
P
V
N
D
G
G
M
M
------------
P
-----
E
L
H
-------
I
G
P
Y
D
H
--------
R
D
P
E
L
H
T
H
--
V
V
G
I
Y
A
N
P
M
A
L
P
E
A
S
K
-
L
P
-
L
Y
T
F
A
Q
Y
----
L
N
S
P
S
Q
Y
N
--------
P
-----------
Q
D
S
W
R
Q
A
V
S
T
L
L
G
E
D
N
L
S
A
M
E
---
K
---------
F
Y
Q
---
S
NTIS
C
-
L
E
P
----
E
E
P
A
Y
L
T
-
N
----------
L
F
K
K
V
Q
E
D
F
ASFRFEQG
L
--
R
T
L
R
E
E
I
I
S
M
Q
T
T
Y
S
R
L
S
T
Q
D
S
K
F
F
-
W
E
I
R
P
W
-----
L
E
------
E
Y
K
L
W
T
D
Y
L
D
Q
A
M
I
T
F
S
N
L
F
A
R
E
S
L
Q
K
A
L
Q
G
R
--
T
Y
L
R
E
V
L
K
D
A
V
-
D
F
R
T
R
V
C
G
D
V
V
R
N
F
L
Q
Q
V
L
R
S
T
V
S
I
E
L
Q
A
E
G
K
E
W
T
A
L
P
P
G
I
V
R
-----------------------------------------------------------------------------------------------
12
HHSearch
29.75
21%
-220
- C5 -
-
5FTO
1
A:
[134-173]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
H
V
A
R
D
I
A
C
----
G
C
Q
Y
L
E
E
N
H
--
F
I
H
R
D
I
A
A
R
N
C
L
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
29.28
15%
-310
- C5 -
-
4YC3
-
CDK1_HUMAN
A:
[112-147]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
L
Y
Q
I
L
Q
----
G
I
V
F
C
H
S
R
R
--
V
L
H
R
D
L
K
P
Q
N
L
L
I
D
D
--------
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
29.22
9%
-120
- C5 -
-
3BYV
1
?
A:
[206-260]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
R
L
Q
L
T
L
Q
V
I
R
----
L
L
A
S
L
H
H
Y
G
--
L
V
H
T
Y
L
R
P
V
D
I
V
L
D
Q
--------
R
G
G
V
F
-
L
T
G
-------
F
E
H
L
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
25.40
6%
-264
- C5 -
-
3AQV
1
AAPK2_HUMAN
A:
[116-153]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
Q
Q
I
L
S
----
A
V
D
Y
C
H
R
H
M
--
V
V
H
R
D
L
K
P
E
N
V
L
L
D
A
--------
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
24.29
27%
33
* C5 *
-
4H62
1
V:
[10-31]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----------
E
K
Q
I
E
E
L
L
D
N
C
I
E
T
F
V
A
E
K
T
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
23.85
14%
-87
- C5 -
-
2W1Z
-
?
B:
[192-243]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
Q
L
T
L
Q
L
I
R
----
L
A
A
S
L
Q
H
Y
G
--
L
V
H
A
D
F
Q
V
R
N
I
L
L
D
Q
--------
R
G
G
V
F
-
L
T
G
-------
F
E
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
21.74
19%
-60
- C5 -
-
1UA2
1
CDK7_HUMAN
C:
[116-162]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
M
L
M
T
L
Q
----
G
L
E
Y
L
H
Q
H
W
--
I
L
H
R
D
L
K
P
N
N
L
L
L
D
E
--------
N
GVLK-
L
A
D
-------
F
G
L
A
K
S
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
18.89
15%
-52
- C5 -
-
5J87
1
BTK_HUMAN
B:
[118-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
K
D
V
C
E
----
A
M
E
Y
L
E
S
K
Q
--
F
L
H
R
D
L
A
A
R
N
C
L
V
N
D
--------
Q
G
V
V
K
-
V
S
D
-------
F
G
L
S
R
Y
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
18.57
30%
13
- C5 -
-
2HI4
1
CP1A2_HUMAN
A:
[112-191]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
R
L
A
Q
N
A
L
N
T
F
S
I
---------
A
S
-
D
P
A
S
--
S
S
S
C
Y
-
L
--
E
E
-
H
V
S
K
E
--------
A
K
A
L
I
S
R
L
--
Q
E
L
M
A
G
P
G
H
F
D
P
Y
N
Q
V
V
V
S
----------
V
A
N
V
I
G
A
M
C
-----
F
G
Q
-
H
F
P
---
E
S
S
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
16.54
24%
-79
- C5 -
-
4BTK
1
TTBK1_HUMAN
A:
[160-209]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
I
L
E
----
S
I
E
A
I
H
S
V
G
--
F
L
H
R
D
I
K
P
S
N
F
A
M
G
R
LPSTYR
K
C
Y
-----
M
L
D
-------
F
G
L
A
R
Q
Y
T
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
16.28
13%
-123
- C5 -
-
4O96
1
?
B:
[95-138]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
Y
D
----
M
F
D
R
L
E
K
K
G
--
I
L
F
V
D
T
T
E
T
N
V
L
Y
D
R
--------
M
RNEFN
P
I
D
-------
I
S
S
Y
N
V
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
15.02
29%
-25
- C5 -
-
4GKI
-
?
G:
[192-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
V
--
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
--------
G
KLIG-
C
I
D
-------
V
G
R
V
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
13.72
29%
-29
- C5 -
-
4GKH
-
?
L:
[192-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
V
--
V
T
H
G
D
F
S
L
D
N
L
I
F
D
E
--------
G
KLIG-
C
I
D
-------
V
G
R
V
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------