@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRJ8: (2017-12-03 )
MRLMINKSMKNIYIMGLLLACSGFAMAETVTQQPTGQPVRTASNPNAIRIVTRPEIMGLWGMEIPNNKKCVEYYNFRSSNDVVIKSGEEWSYGIYEYQPSDDPKEQLSALVMQIKFDNNKVDCSGQKQDQTGDISQYFVQWKNDHTINFCSTAKGEQCFATLRRMLP
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..-......30.----------.-.....--.40.....-...50..---------..-----....60---------.......--------..70--........----.80..--...--.--..-----90---..---..-------..--..100----.........110.......120.......130.......140.---..--------....150----.........160.....------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
R
L
M
INKSM
K
N
I
Y
I
M
G
L
L
L
ACSG-
F
A
M
A
E
T
VTQ----------Q-PTGQP--VRTASNP
N
-
A
I
R
I
V
TR---------P
E
-----
I
M
G
L
W----------GMEIPNN--------
K
K
C
---
V
E
YYNFRS----SN
D
V
V
--
I
KS--G--EE-----WS---
Y
G
---
I
Y
-------EY--QPS------D
D
P
K
E
Q
L
S
A
L
V
M
Q
I
K
FDNNKVDCSGQKQDQTG
D
I
S
Q
Y
F
V
Q
WKN---D
H
--------
T
I
N
F
C------STAK
G
E
Q
C
F
A
T
L
R
R
MLP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
58.20
23%
60
- C6 -
-
5L2D
-
?
A:
[19-252]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMWVDFSDTASMKNLDPQGGFK
V
G
T
V
F
K
K
E
I
S
P
G
Y
V
V
T
L
T
V
T
E
L
K
P
F
N
S
T
E
I
Y
K
K
----------
R
-
V
E
G
T
P
--
T
A
N
T
Y
D
P
N
-
A
I
N
S
Y
L
K
GYKDYGKTP
P
S
-----
V
T
G
R
T
----------
Q
I
I
L
P
D
D
AVN
W
G
I
K
F
K
V
E
---
A
T
Y
R
G
N
P
V
----
K
P
S
V
V
--
M
A
D
--
G
--
E
D
-----
A
N
PAE
Y
G
---
I
F
T
T
NGEGW
E
Y
VG
E
W
M
------
K
G
P
Y
T
V
M
T
-
E
D
M
V
K
A
F
D
K
T
R
K
D
G
L
L
I
L
K
D
K
S
V
D
W
S
K
Y
L
------------------
S
P
D
T
V
------
T
G
G
L
G
S
Q
V
F
G
P
I
I
S
A
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
54.52
27%
24
- C5 -
-
5M11
6
?
A:
[11-758]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------GIWNTLLAIHKTE
K
A
V
E
T
PK
K
V
F
A
V
A
NG
V
L
Y
S
V
G
K
EAPHE
A
K
I
F
D
RISGLSDTSVS
S
I
A
Y
SEQLK
S
L
V
I
Y
Y
ASG
N
I
D
I
L
D
EAG
R
V
T
N
V
PALKDNIDLIDKTLNRLLIVGN
R
A
Y
L
A
G
GF
G
L
S
V
L
DVAEARIPATYAKGTKVT
D
V
A
K
L
D
ND
R
L
L
M
L
K
EG
Q
L
F
I
G
K
ETDNLQDPAA
W
T
A
L
S
L
NLPMGSVT
G
L
G
I
V
GE
D
I
C
F
L
L
ADG
R
V
Y
V
A
A
NQSFEPELLLSSSAD
S
R
L
Y
V
T
DRGLFICAEN
R
I
Y
F
I
E
K
GR
K
T
T
Q
F
PIADVL
G
V
G
A
M
NESN
T
A
Y
I
A
LGEE
G
L
A
S
L
L
LAEGS
T
A
E
A
M
P
V
A
F
D
G
P
GDNDFY
E
M
R
F
S
HG
R
L
Y
A
A
S
G
L
W
G
TNLMGHA
G
M
V
K
L
Y
D
G
N
R
W
T
N
F
D
--------------
K
K
T
V
Q
E
----------
Q
-
L
G
G
G
F
------
S
F
N
D
-
A
I
D
I
A
V
S
---------
N
G
DPD
H
F
F
V
G
T
W
----------
G
N
G
--------------------
L
F
E
F
K
D
----
G
K
A
I
A
--
R
Y
S
--
G
--
N
E
----------
T
A
---
I
A
-------
E
C
--
N
P
G
------
D
-------
A
R
V
K
A
I
A
F
D
N
K
G
-
N
L
W
G
T
L
G
A
V
G
K
N
I
F
M
Y
D
P
Q
S
S
T
---
W
H
--------
S
F
S
Y
-------
P
D
V
A
N
L
A
S
F
G
N
M
I
I
-
L
P
NG
D
K
W
V
N
I
LHRSGGSTR
K
G
V
L
I
F
N
DRGTPETTSD
D
S
H
L
Y
V
E
Q
F
V
N
RLGAAIGHKTIY
A
M
A
V
D
HNG
S
V
W
M
G
S
DI
G
I
F
G
V
Y
NAAGVLSSTST
P
I
A
V
R
P
VGGEEP
N
L
Y
Y
VLDKVTVT
D
I
V
V
D
KLN
H
K
W
V
A
T
QGT
G
L
Y
L
L
S
EDCSKIL
A
Q
F
T
VENSPLLSNNILSLALNDDNG
L
L
Y
I
GTAD
G
L
M
T
F
QTGTGSGSASELDG
V
Y
V
Y
PNPLRPEYPD
G
V
T
I
A
GLQAG
C
S
V
K
I
T
D
TTGRLL
Y
Q
T
E
SVTT
E
V
K
W
NARGADG
N
R
V
A
S
G
V
Y
A
V
A
V
Y
D
PVSK
K
S
K
L
I
R
F
A
V
I
R-------------------------------------------------------------------
14
Fugue
50.22
15%
32
- C6 -
-
3UGM
-
PTHX1_XANOP
A:
[169-1048]
KPKVRELVAHIVALSQHPAALGTVAVTYQHIITALAT
H
E
D
I
V
G
V
G
KQWSG
A
R
A
L
E
A
L
L
T
D
A
G
E
L
RGPPLQLDT
G
Q
L
V
K
I
A
K
R
GG
V
T
A
M
E
A
V
H
A
SRNALTPLNLT
P
A
Q
V
V
A
I
A
SNNG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
HGLTPA
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
M
Q
R
L
L
P
V
L
C
Q
A
HGLP
P
D
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
E
T
V
Q
R
L
L
PVLCQAHGLT
P
D
Q
V
V
A
I
A
SHGG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SNGG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
S
NGG
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
R
LL
P
V
L
C
Q
THGLT
P
A
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
Q
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
A
T
V
Q
R
LLPVLCQAHGLTPDQV
V
A
I
A
S
N
GGG
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
SNGG
G
K
Q
A
L
E
T
V
Q
R
LL
P
V
L
C
Q
A
H
G
L
T
Q
V
Q
V
V
A
I
A
S
N
I
G
G
-
K
Q
A
L
E
T
V
Q
R
----------
L
L
P
V
L
C
Q
--
A
H
G
L
T
P
A
Q
-
V
V
A
I
A
S
H
---------
D
G
-----
G
K
Q
A
L
----------
E
T
V
Q
R
L
L
--------
P
V
L
---
C
Q
A
H
G
L
T
P
----
D
Q
V
V
A
--
I
A
S
NG
G
--
G
K
-----
Q
A
---
L
E
---
T
V
-------
Q
R
--
L
L
P
------
G
L
T
Q
E
Q
V
V
A
I
A
S
----
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
-
G
L
T
P
---
D
Q
--------
V
V
A
I
A
------
S
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
VLCQAHGLT
P
A
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
DHGLT
L
A
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
E
T
V
Q
R
L
LPVLCQGLT
Q
D
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQDHGLT
P
D
Q
V
V
A
I
A
S
NIGGKQ
A
L
E
T
V
Q
R
L
L
PVLCQDHGLT
L
D
Q
V
V
A
I
A
S
N
GGK
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
DHGLTPDQVVAIASNSG----------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.84
26%
-61
- C5 -
-
4FFN
2
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
45.32
26%
-57
- C5 -
-
4FFR
1
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.10
26%
-59
- C5 -
-
4FFL
2
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.07
26%
-56
- C5 -
-
4FFM
2
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
44.44
26%
-64
- C5 -
-
4FFP
2
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.25
26%
-55
- C5 -
-
4FFO
2
?
A:
[214-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
N
L
P
L
K
G
I
M
D
V
E
A
I
F
G
P
K
G
-
L
R
V
I
E
I
D
A
R
----------
F
-
P
S
Q
T
P
T
V
V
Y
Y
S
S
G
I
N
-
L
I
E
L
L
F
R
---------
A
F
-----
T
D
G
V
E
----------
E
I
---
E
N
--------
K
Y
C
---
I
Y
E
H
L
M
F
G
----
E
N
G
V
L
--
I
P
V
--
G
--
E
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
39.26
15%
136
- C6 -
-
1NG6
-
YQEY_BACSU
A:
[1-148]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS
L
L
E
R
L
N
Q
D
M
K
L
Y
M
K
N
R
E
K
D
K
L
T
V
-
V
R
M
V
K
A
S
L
Q
----------
N
-
E
A
I
K
L
--
K
K
D
S
---------
L
T
E
---------
D
E
-----
E
L
T
V
L
----------
S
R
E
L
K
Q
R
--------
K
D
S
---
L
Q
E
F
S
N
A
N
----
R
L
D
L
V
--
D
K
V
--
Q
--
K
E
-----
L
D
---
I
----
L
E
-------
V
Y
--
L
P
E
------
Q
L
S
E
E
E
L
R
T
I
V
N
E
T
I
A
E
V
G
A
--------
S
S
K
A
D
M
G
K
V
M
G
A
I
M
P
---
K
V
--------
K
----------
G
K
A
D
G
S
L
I
N
K
L
V
S
S
Q
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
36.77
29%
-511
* C6 *
-
4ER9
1
C562_SALTY
A:
[89-102]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
I
L
V
G
Q
I
D
G
A
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
36.73
23%
-20
- C5 -
-
2MHD
-
?
A:
[9-59]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---------
P
Q
-----
L
V
G
K
W
----------
I
V
K
E
P
-
V
---------
L
Q
DD
F
V
T
C
Y
T
F
N
A
----
D
K
T
Y
E
--
V
Y
T
--
G
--
S
P
LSNG
V
P
F
---
R
G
---
T
Y
-------
I
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
36.47
16%
90
- C5 -
-
5L8S
-
?
A:
[1-604]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
I
N
F
P
K
PT
V
E
Q
F
F
R
T
Y
T
I
T
N
F
A
V
S
SDEK
R
L
V
F
N
A
NLNG
K
M
N
L
W
A
M
DLPDTYPYLFAHRDESCN
F
I
K
F
DPENR
Y
V
L
A
G
F
D
K
DGDEN
Y
Q
I
Y
A
I
P
NEGGL
P
H
P
L
I
T
G
D
A
S
E
K
Y
Y
F
S
H
L
S
A
D
G
K
-
C
V
Y
Y
E
T
S
K
E
----------
N
-
P
S
F
L
N
--
T
R
I
R
N
L
E
T
G
E
D
R
L
L
N
V
---------
G
E
-----
V
S
T
T
E
----------
L
A
A
V
S
E
N
--------
E
E
S
---
F
V
Y
L
R
A
F
A
----
N
T
Y
I
V
G
F
V
K
M
--
G
--
E
E
------------------------
T
F
--
N
I
T
------
P
D
P
E
K
V
H
--
V
A
M
E
P
V
F
T
D
N
E
T
I
Y
F
A
T
D
Y
D
S
D
---
E
M
Y
L
A
K
F
D
L
---
T
S
--------
K
E
F
S
K
------
V
L
A
F
D
G
E
S
I
Q
S
V
K
W
D
K
D
NK
A
F
Y
L
I
T
V
KGV
T
D
I
L
Y
R
Y
D
VATD
K
V
E
E
C
S
L
PVDIIE
Q
I
Q
V
A
KSG
N
L
Y
I
L
GRSATV
P
H
N
V
Y
Q
S
SNGV
E
W
K
Q
LTNNRVLGLSPED
M
V
E
P
D
I
V
S
Y
T
S
FDG
M
E
I
E
A
L
L
F
K
A
K
PENDNG
Y
T
I
F
W
P
H
G
GPQ
S
A
E
R
K
M
F
R
S
M
F
Q
C
F
I
N
R
G
Y
T
I
F
A
P
NFRGSTGYG
S
A
F
T
K
LVELDWGE
G
P
R
L
D
C
I
A
G
I
E
W
L
F
E
S
GFTDRNK
L
F
L
V
G
G
S
Y
G
G
Y
M
A
L
L
L
H
G
R
HSDYFR
A
V
V
D
I
FGPSD
L
F
T
F
I
N
S
VPPHW
K
P
I
M
E
R
W
LGDPERD
K
E
R
F
I
K
D
SPVTYLDGMV
K
P
M
L
V
I
Q
G
AKDPRVV
K
E
E
S
D
Q
I
V
A
K
L
K
E
K
GRD
V
E
Y
L
V
L
EDEGHGFSK
K
E
N
E
I
K
V
Y
S
L
M
L
A
F
L
E
K
H
QALE
H
H
H
H
HH
13
Fugue
36.44
10%
-2
- C6 -
-
3HK0
-
GRB10_HUMAN
A:
[8-250]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K
Q
D
V
K
V
F
S
EDG
T
S
K
V
V
E
I
L
A
D
M
-
T
A
R
D
L
C
Q
L
L
V
Y
K
S
-
W
T
L
V
E
H
H
P
H
LG
L
E
R
C
L
EDH
E
-
L
V
V
Q
V
--
E
S
T
M
A
S
E
S
-
K
F
L
F
R
K
N
---------
Y
A
-----
K
Y
E
F
F
K
N
PMNFFPEQ
M
V
T
W
S
Q
Q
--------
S
L
L
---
Q
N
F
L
N
S
S
S
S
P
E
I
Q
G
F
L
H
--
V
K
E
--
L
GK
K
S
-----
W
K
---
K
L
---
Y
V
-------
C
L
--
R
R
S
G
L
Y
C
S
T
K
G
T
S
A
A
P
R
H
L
Q
L
L
A
D
L
E
D
S
N
I
F
S
L
I
A
G
R
K
Q
Y
N
A
P
T
D
H
G
L
C
I
K
P
---
N
K
VRNETKE
L
R
L
L
C
A
------
E
D
E
Q
T
R
T
S
W
M
T
A
F
R
L
L
K
YG
M
L
L
Y
Q
N
Y
R
I-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
32.84
4%
-9
- C6 -
-
3GN3
1
?
A:
[4-182]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
S
D
A
L
S
W
G
H
G
P
R
L
F
E
V
F
L
E
-
P
T
C
P
F
S
V
K
A
----------
F
-
F
K
L
D
D
--
L
L
A
Q
A
G
E
D
-
N
V
T
V
R
I
R
L
Q
S
Q
PWH--
M
F
-----
S
G
V
I
V
----------
R
C
I
L
A
A
A
--------
T
L
E
---
G
G
K
E
S
A
K
A
----
V
M
T
A
V
--
A
S
H
--
R
--
E
E
-----
F
E
---
F
E
----
H
-------
H
A
--
G
G
P
------
N
L
D
A
T
P
N
D
I
I
A
R
I
E
R
Y
S
G
L
A
L
A
E
A
F
A
N
P
E
L
E
H
A
V
K
W
H
T
K
Y
A
R
Q
N
GI
H
V
--------
S
P
T
F
M
I
NGLVQ
P
G
M
S
S
G
D
P
V
S
K
W
V
S
D
I
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
32.11
8%
13
* C7 *
-
1Y7X
-
A:
[1-113]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
--
M
Q
V
V
L
P
N
T
-
A
L
H
L
K
A
L
---------
L
D
-----
F
E
D
K
D
----------
G
D
K
V
V
A
G
--------
D
E
W
---
L
F
E
-----------------
G
P
--
G
--
T
Y
-----
I
P
---
R
K
---
E
V
-------
E
V
--
V
E
I
------
I
Q
A
T
I
I
R
Q
N
Q
A
L
R
L
R
A
R
K
E
C
W
D
R
D
G
K
E
R
V
T
G
---
E
E
W
L
V
T
T
V
G
---
A
Y
--------
L
-----------
P
A
V
F
E
E
V
L
D
L
V
D
A
V
I
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
29.88
12%
-130
- C5 -
-
2Y2Y
-
?
A:
[49-97]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
----
E
K
T
L
S
--
L
P
A
--
N
--
Q
P
-----
I
A
---
L
T
---
K
L
-------
S
L
--
N
I
S
------
P
D
D
R
---
V
K
I
V
V
T
V
S
-
D
G
Q
S
L
H
L
S
Q
Q
W
P
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
29.85
10%
-66
- C5 -
-
2N59
-
?
A:
[47-98]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
----
A
G
A
F
T
--
A
I
A
--
E
--
Q
R
-----
V
T
---
V
G
---
N
V
-------
V
L
--
D
Y
S
------
S
A
N
R
---
Y
A
A
R
L
D
V
S
F
G
S
V
T
I
Q
C
N
L
D
P
E
T
V
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
29.10
29%
-56
- C3 -
-
4XYD
-
?
B:
[6-14]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
S
M
A
R
N
I
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
27.98
35%
14
* C8 *
-
3RY3
-
?
A:
[64-102]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
L
K
Q
--
N
--
E
D
-----
F
S
---
W
D
S
LL
L
S
-------
Q
Y
--
Q
P
S
------
D
D
G
K
T
W
L
L
T
L
K
P
D
L
K
F
S
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------