@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRR7: (2017-12-04 )
MLQAVYLTPIELHQTPDWSDRPYNIHRDPLWKTEKQGKEFDDVWFYHCDHLGTPQEMTDHTGAIIWKAEYKAWGECKAEKAKSNFFENSEIISNNIRFQGQYFDEETGLHYNRYRYYSPYVGRFVSKDPIGLLGGSNNYAYAPSPTEWVDPLGLSCQKIPKGFKSFGQLKQFGQAMQAGFSKLGFKGATMYMQGSAHSGRSFETGKAFDDGRVSDFDIAVVQPELFEKAKKMGIAKGNRTLPIEINSVEANKLGINGVLQKMSKLAGGRDVNVMIFDSPESAKAKAEGTRIPANCM
Atome Classification :
(20 SA)
--------------------.........10....-...---.20....----.-...30.-.......40........50-..--....-..60........70------........80---...-----------......90..-......100....-....110---------.--....-..-120----.........130...------------------....140-.-......-150......-------------------.160....-----...170------........180......---------..-.---190.......200.......210...-....---..-220...---....230---------.......-240---.-------....-.----------..250.---.....-..--.-260.....-----..-270----.........--280-.....-..290....---------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------M
L
Q
A
V
Y
L
T
P
I
E
LHQT-PDW---SDRPYNI----H-RDPLWK-
T
E
KQGKEFD
D
V
W
F
YHCDHL-G
T
--
P
Q
E
M-TDHT
G
A
I
I
W
K
AEY
K
------
A
W
G
E
C
K
A
E
K
----
A
KS-----------NFFENSEIIS-NN
I
R
F
Q
G
Q
-YFDE-ETGLHY
N
---------
R
--
Y
R
Y
Y-S
P
-
Y
------
V
G
R
FVSKDP
I
G
L
LGG------------------SNNYAYA-P-SPTEWV-DPLG
L
S
C
Q
K
-------------------
I
P
K
G
F
K
S
F
-----
G
Q
L
K
Q
-------
F
G
Q
A
M
Q
A
G
F
--
S
KLGFK---------G
A
-
T
---
M
Y
M
QGSAHSGRSFETGKAFDD--GRV-SDF
D
---
I
A
-VV
Q
P
E
L
---
F
E
K
A
K
KM---------GIAKGN
R
-
T
L
----
P
-------
I
E
I
N-S----------VEA--N---KL
G
I
N
-
G
V
--
L
-
Q
K
M
S
K
LAG-----G
R
-
D
------
V
N
V
M
I
FDSP--ESA-KAKAE-GTRIPANCM---------------------
24
Fugue
64.25
17%
44
- C2 -
-
3J9O
-
?
B:
[79-505]
V
I
D
K
L
I
D
L
Q
V
N
S
I
I
S
ND
E
F
R
A
L
E
Q
E
W
L
K
V
Q
E
V
C
Q
--
E
D
Y
---
D
N
V
E
V
S
I
L
D
V
K
K
-
E
E
L
Q
Y
D
-
F
E
R
N
L
Y
D
I
S
S
S
D
F
F
K
K
V
Y
V
-
S
E
F-
D
Q
Y
G
-
G
E
P
Y
G
A
I
L
G
L
Y
N
F
E
NT
T
N
D
I
I
W
L
T
G
M
G
M
V
----
A
K
N
S
H
A
P
F
I
A
S
I
D
K
S
F
F
G
V
K
D
L
S
E
I
T
H
I
K
S
F
E
A
-
L
L
E
H
-
P
R
Y
K
E
W
N
---------
D
--
F
R
N
L
-
D
V
-
A
AY
I
G
L
T
V
G
D
F
M
L
R
Q
P
Y
N
P
E
N
N
PVQYKLMEGFNE
F
V
D
Y
D
K
N
E
S
Y
L
W
G
-
P
-
A
S
I
H
L
V
-
K
N
M
M
R
S
Y
D
K
TRWFQYIRGVESGGYVKNL
V
A
C
V
Y
D
N
K
-----
G
I
L
E
T
K
S
PLNVL
F
A
D
Y
M
E
L
S
L
--
A
N
I
G
L
I
PFVSEKGTS
N
A
-
C
---
F
F
S
V
N
S
A
K
K
V
E
E
F
V
D
G
F
D
S
A
N
--
S
R
L
I
A
N
L
S
---
Y
T
-
M
C
I
S
R
I
---
S
H
Y
I
K
C
V
IRDKIGSIV
D
V
E
S
I
Q
K
-
I
L
----
S
-------
D
W
I
S
-
E
FVTTVYQPTP
L
E
M
--
A
---
R
Y
P
F
R
-
N
V
--
S
-
I
E
V
K
T
I
P
G
KPG
W
Y
S
C
-
K
------
I
N
V
I
P
H
I
Q
F
--
E
G
M
-
N
T
T
M
T
I
D
T
R
L
E
P
E
L
F
GTNN-----------------
12
HHSearch
59.00
35%
-4
- C6 -
-
4O9X
-
?
A:
[2081-2191]
---------------------------------------------------------------------
N
N
Q
L
R
Y
S
Y
D
N
L
I
-
G
S
--
S
Q
L
E
-
L
D
S
E
G
Q
I
I
S
E
E
E
Y
Y
------
P
Y
G
G
T
A
L
W
A
----
A
R
N
---------------
Q
T
E
A
S
Y
-
K
T
I
R
Y
S
G
K
-
E
R
D
--
A
T
G
L
Y
Y
Y
---------
G
--
Y
R
Y
Y
-
Q
P
-
W
------
I
G
R
W
L
S
S
D
P
A
G
T
I
D
G
------------------
L
N
L
Y
R
M
V
R
N
-
N
P
V
T
L
L
-
D
P
D
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
55.75
11%
15
* C2 *
-
2ODF
-
?
A:
[6-257]
--------------------------------
R
F
F
-
T
E
A
---
E
G
K
A
V
G
V
----
E
-
N
A
A
-----------
A
K
G
D
V
L
L
V
C
E
H
A
-
S
A
TI
P
Q
K
Y
-
G
T
L
G
L
S
A
D
V
L
S
S
H
A
------
A
W
----------------------------------
D
-
P
G
A
L
A
V
A
R
-
L
L
S
E
-
K
F
H
A
T
L
V
---------
Y
--
Q
R
F
S
-
R
L
-
V
------
Y
D
C
N
R
P
P
E
S
P
S
A
M
P
V
------------------
K
S
E
I
Y
D
I
-
P
-
G
N
F
-------
D
L
D
E
A
E
-------------------
R
F
A
R
T
S
A
L
-------
Y
V
P
-------
F
H
D
R
V
S
E
I
I
--
A
E
R
Q
A
A
---------
G
R
-
K
---
V
-
V
V
V
T
I
H
S
F
T
P
V
Y
------
H
--
G
R
F
-
R
E
V
E
---
I
G
-
I
L
H
D
N
D
---
S
R
L
A
D
A
M
---------
L
A
G
A
E
G
A
-
S
L
----
T
-------
V
R
R
N
-
D
----------
P
Y
G
--
P
---
E
D
G
V
T
-
H
T
--
L
-
R
L
H
A
L
P
D
G
-----
L
L
-
N
------
V
M
I
E
I
R
N
D
L
IA
N
E
G
-
E
Q
A
A
I
-
A
G
F
L
H
E
L
M
G
K
A
L
S
S
I
E
E-------------
10
HHSearch
54.67
31%
-3
- C6 -
-
4IGL
1
?
D:
[581-690]
----------------------------------------------------------------------
D
Q
I
R
W
S
Y
D
N
L
T
-
C
S
--
S
G
L
E
-
V
D
G
D
G
L
V
I
S
M
E
E
Y
Y
------
P
Y
G
G
T
A
V
W
A
----
A
R
S
---------------
H
I
E
T
A
Y
-
K
T
V
R
Y
S
G
K
-
E
R
D
--
A
T
G
L
Y
Y
Y
---------
G
--
F
R
Y
Y
-
Q
P
-
W
------
A
G
R
W
L
S
A
D
P
A
G
T
V
D
G
------------------
L
N
L
Y
R
M
V
R
N
-
N
P
L
R
L
T
-
D
P
D
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
54.05
31%
-8
- C6 -
-
4IGL
-
?
B:
[581-690]
----------------------------------------------------------------------
D
Q
I
R
W
S
Y
D
N
L
T
-
C
S
--
S
G
L
E
-
V
D
G
D
G
L
V
I
S
M
E
E
Y
Y
------
P
Y
G
G
T
A
V
W
A
----
A
R
S
---------------
H
I
E
T
A
Y
-
K
T
V
R
Y
S
G
K
-
E
R
D
--
A
T
G
L
Y
Y
Y
---------
G
--
F
R
Y
Y
-
Q
P
-
W
------
A
G
R
W
L
S
A
D
P
A
G
T
V
D
G
------------------
L
N
L
Y
R
M
V
R
N
-
N
P
L
R
L
T
-
D
P
D
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
51.76
36%
51
- C6 -
-
4O9X
-
?
A:
[2086-2191]
---------------------------------------------------------------------------
Y
S
Y
D
N
L
I
G
S
--
S
Q
L
E
-
L
D
S
E
G
Q
I
I
S
E
E
E
Y
Y
------
P
Y
G
G
T
A
L
W
A
----
A
R
N
-----------
Q
----
T
E
A
S
Y
-
K
T
I
R
Y
S
G
K
-
E
R
D
A
--
T
G
L
Y
Y
Y
---------
G
--
Y
R
Y
Y
-
Q
P
-
W
------
I
G
R
W
L
S
S
D
P
A
G
T
I
D
G
------------------
L
N
L
Y
R
M
V
-
R
N
N
P
V
T
L
L
-
D
P
D
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.76
30%
50
- C6 -
-
4IGL
-
?
B:
[570-690]
-----------------------------------------------------------
W
E
-
S
G
K
P
D
G
I
I
N
D
Q
I
R
W
S
Y
D
N
L
-
T
C
--
S
S
G
L
E
V
D
G
D
G
L
V
I
S
M
E
E
Y
Y
------
P
Y
G
G
T
A
V
W
A
----
A
R
S
-----------
H
I
----
E
T
A
Y
-
K
T
V
R
Y
S
G
K
-
E
R
D
A
--
T
G
L
Y
Y
Y
---------
G
--
F
R
Y
Y
-
Q
P
-
W
------
A
G
R
W
L
S
A
D
P
A
G
T
V
D
G
------------------
L
N
L
Y
R
M
V
R
N
-
N
P
L
R
L
T
-
D
P
D
G
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
49.39
20%
41
* C5 *
-
3KDR
1
?
A:
[7-297]
AVTT
R
A
E
A
L
T
I
P
A
V
L
R
A
R
N
L
L
S
T
T
V
A
R
T
P
L
V
C
D
G
T
L
P
P
F
VPV
A
A
P
P
G
A
A
----
T
M
Q
T
P
F
H
R
M
L
----
A
T
A
D
D
L
L
F
N
-------------------
G
V
A
C
W
A
L
D
R
D
------
E
S
G
--
T
C
I
G
----
A
I
H
-----------
I
P
L
D
T
W
Q
I
E
E
-
N
T
V
R
V
N
G
K
-
A
V
D
---------------------------
P
M
E
------
V
C
I
F
V
-----
G
I
H
G
G
--------------------
L
L
T
H
A
-
S
-
E
T
F
T
D
A
-
R
N
L
V
R
A
A
A
R
-------------------
V
A
Q
N
P
A
A
L
-----
I
E
L
R
Q
-------
T
N
N
A
--------
Q
L
S
P
D
---------
D
V
-
D
---
R
I
I
N
G
Y
V
A
A
R
R
G
R
N
S
G
V
G
F
S
S
--
S
G
L
-
E
V
H
E
---
H
E
M
A
K
E
N
L
L
---
I
E
G
R
N
A
A
---------
A
V
D
V
A
R
A
M
N
V
----
P
AAFIDAT
V
G
Q
N
-
A
----------
A
S
R
M
-
I
---
E
L
V
T
F
-
G
V
E
P
L
M
S
A
I
E
A
R
L
N
-----
Q
P
-
D
MHADHL
A
N
P
L
K
F
D
P
A
--
A
L
L
-
D
A
I
P
T
-------------------------------
22
Fugue
48.45
18%
-17
- C5 -
-
1YLQ
-
?
A:
[1-92]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
-------
H
M
K
E
I
K
E
I
T
--
K
K
D
-
V
Q
---------
D
A
-
E
---
I
Y
L
Y
G
S
V
V
E
G
D
Y
--------
S
--
I
G
L
-
S
D
I
D
---
V
A
-
I
V
S
D
V
F
---
E
D
R
N
R
K
L
---------
E
F
F
G
K
I
T
-
K
K
F
FDS
P
-------
F
E
F
H
-
I
----------
L
T
K
--
K
---
E
W
K
M
S
K
R
F
--
I
-
R
K
Y
R
R
L
--------------------------------------------------------------------
21
Fugue
47.31
16%
18
- C2 -
-
4UY5
1
EGTD_MYCS2
A:
[2-327]
----------------------------
T
L
S
L
A
N
Y
-
L
A
A
---
D
S
A
A
E
A
L
----
R
-
R
D
V
R
A
G
-
L
T
A
A
P
K
S
L
P
P
K
W
F
Y
D
A
V
G
S
-
D
L
--
F
D
Q
I
-
T
R
L
P
E
Y
Y
P
T
R
T
E
A
Q
------
I
L
R
T
R
S
A
E
I
----
I
A
A
-----------
A
G
A
D
T
L
V
E
L
G
-
S
G
T
S
E
K
T
R
M
L
L
D
A
M
R
D
A
---
E
---------
L
--
L
R
R
F
-
I
P
-
F
------
D
---
V
D
A
G
V
L
R
S
A
G
A
------------------
A
I
G
A
E
Y
P
-
G
-
I
E
I
D
A
V
C
G
D
F
E
E
H
L
G
K
-------------------
I
P
H
V
G
R
R
L
V
V
F
L
G
S
T
I
G
N
-------
L
T
P
A
P
R
A
E
F
--
L
S
T
L
A
D
---------
T
L
-
Q
PG
D
S
L
L
L
G
T
D
L
V
K
D
T
G
R
L
V
R
A
Y
D
D
AA
G
V
T
-
A
A
F
N
R
N
V
L
A
-
V
V
N
R
E
L
SAD
F
D
L
D
A
F
E
---------
H
V
A
K
W
N
S
-
D
-----
E
-------
E
R
I
E
M
W
----------
L
R
A
--
R
T
A
Q
H
V
R
V
A
-
A
L
--
D
-
L
E
V
D
F
A
A
G
-----
E
E
M
L
------
T
E
V
S
C
K
F
R
P
--
E
N
V
-
V
A
E
L
A
-
E
A
G
L
R
Q
T
H
W
W
T
D
PAGD
F
G
L
S
L
A
V
R
L
E
H
H
H
H
9
PsiBlast_PDB
42.14
25%
109
- C4 -
-
2IOY
1
?
A:
[108-228]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
E
M
A
A
E
F
I
A
K
A
L
K
G
K
---------
G
N
-
V
---
V
E
L
E
G
I
P
G
A
S
A
A
R
D
R
G
K
G
F
D
E
A
I
A
K
Y
-
P
D
I
K
---
I
V
-
A
K
Q
A
A
D
---
F
D
R
S
K
G
L
---------
S
V
M
E
N
I
L
-
Q
A
----
Q
-------
P
K
I
D
-
A
----------
V
F
A
QN
D
---
E
M
A
L
G
-
A
I
-----
K
A
I
E
A
A
N
-----
R
Q
-
G
------
I
I
V
V
G
F
D
G
T
--
E
D
A
L
K
A
I
K
E
-
G
-----------------------------
6
PsiBlast_PDB
39.85
24%
-8
- C4 -
-
4RBM
5
KGP83_PORGN
A:
[125-231]
-----------------------------------------------------------------------------------
S
--
P
E
E
L
-
T
N
I
I
D
K
V
L
M
Y
E
K
A
T
------
M
P
D
K
S
Y
L
E
K
V
L
L
I
A
G
A
-----------
D
Y
S
W
N
S
Q
V
G
Q
-
P
T
I
K
Y
G
M
Q
-
Y
Y
Y
N
-
Q
E
H
G
Y
T
D
---------
V
--
Y
N
Y
L
K
A
P
-
Y
------
T
G
C
Y
-
S
H
L
N
T
G
V
--
S
------------------
F
A
N
Y
T
A
H
-
G
-
S
E
T
A
W
A
-
D
P
L
L
T
T
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
38.86
22%
-4
- C3 -
-
1DLI
4
UDG_STRPY
A:
[236-352]
---------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
G
I
-
S
Y
D
D
-
R
I
G
M
H
Y
N
---------
N
--
P
S
F
---
G
-
Y
------
G
G
Y
C
L
P
K
D
T
K
Q
L
L
A
N
------------------
Y
N
N
I
-------
P
Q
T
L
I
-
E
A
I
-
V
S
S
N
N
-------------------
V
R
K
S
Y
I
A
---------
K
Q
-------
I
I
N
V
L
K
E
Q
E
--
S
P
V
K
V
V
---------
G
V
Y
R
---
L
I
M
K
S
N
S
D
N
F
R
E
S
A
I
K
D
V
I
D
I
--
L
K
S
-
K
D
I
K
---
I
I
-
I
Y
E
P
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.62
24%
-4
* C4 *
-
4TKX
8
KGP83_PORGN
L:
[125-231]
-----------------------------------------------------------------------------------
S
--
P
E
E
L
-
T
N
I
I
D
K
V
L
M
Y
E
K
A
T
------
M
P
D
K
S
Y
L
E
K
VLLI
A
G
A
-----------
D
Y
S
W
N
S
Q
V
G
Q
-
P
T
I
K
Y
G
M
Q
-
Y
Y
Y
N
-
Q
E
H
G
Y
T
D
---------
V
--
Y
N
Y
L
K
A
P
-
Y
------
T
G
C
Y
-
S
H
L
N
T
G
V
--
S
------------------
F
A
N
Y
T
A
H
-
G
-
S
E
T
A
W
A
-
D
P
L
L
T
T
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
38.10
33%
-45
- C6 -
-
5MF9
-
A:
[22-53]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
-
Y
Y
D
P
-
T
T
G
L
Y
Y
D
---------
P
NS
Q
Y
Y
Y
-
N
S
-
L
------
T
Q
Q
Y
L
Y
W
D
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
37.56
22%
-3
* C3 *
-
1DLJ
4
UDG_STRPY
A:
[236-352]
---------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
G
I
-
S
Y
D
D
-
R
I
G
M
H
Y
N
---------
N
--
P
S
F
---
G
-
Y
------
G
G
Y
S
L
P
K
D
T
K
Q
L
L
A
N
------------------
Y
N
N
I
-------
P
Q
T
L
I
-
E
A
I
-
V
S
S
N
N
-------------------
V
R
K
S
Y
I
A
---------
K
Q
-------
I
I
N
V
L
K
E
Q
E
--
S
P
V
K
V
V
---------
G
V
Y
R
---
L
I
M
K
S
N
S
D
N
F
R
E
S
A
I
K
D
V
I
D
I
--
L
K
S
-
K
D
I
K
---
I
I
-
I
Y
E
P
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
37.33
42%
-129
- C3 -
-
3QOY
-
RL1_AQUAE
A:
[113-140]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
F
D
---
V
A
-
I
A
T
P
E
M
---
M
P
K
V
A
K
L
---------
G
R
I
L
G
P
R
-
G
L
---------------------------------------------------------------------------------------------------------------------------
14
HHSearch
35.16
38%
-45
- C6 -
-
3WKN
-
?
G:
[12-44]
------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
V
Y
D
P
-
E
T
G
T
W
Y
D
AAWHLGELV
W
--
A
T
Y
Y
-
D
P
-
E
------
T
G
T
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
31.72
33%
-8
- C6 -
-
2MXW
-
A:
[25-56]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
-
Y
Y
D
P
-
Q
T
G
L
Y
Y
D
PN-------
S
--
Q
Y
Y
Y
-
N
A
-
Q
------
S
Q
Q
Y
L
Y
W
D
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
24.08
24%
25
* C6 *
-
2MXW
-
A:
[16-46]
----------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
Y
-
Q
Y
D
E
-
T
S
G
Y
Y
Y
D
---------
P
QT
G
L
Y
Y
-
D
P
-
N
------
S
Q
Y
Y
Y
N
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------