@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VRX4: (2017-12-05 )
MEDALQNLKVMVIDDSKTIRRTAETLLQREGCEVITAVDGFEALSKIAEANPDIVFVDIMMPRLDGYQTCALIKNSQNYQNIPVIMLSSKDGLFDQAKGRVVGSDEYLTKPFSKDELLNAIRNHVSS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90.......---.100.......110.......120.....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
E
D
A
L
Q
N
L
K
V
M
V
IDD
S
K
T
I
R
R
T
A
E
T
L
L
Q
REG
C
E
V
I
T
AV
D
G
F
E
A
L
S
K
I
AEANP
D
I
V
F
V
D
IMMPRLDG
Y
Q
T
C
A
L
IKNSQNYQNI
P
V
I
M
LSSKDGL
F
D
QAK---
G
R
V
VGSDEYLTKPF
S
K
D
E
L
L
N
A
I
R
N
HVSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
173
Fugue
87.02
33%
-134
- C2 -
-
1W25
3
PLED_CAUCN
A:
[1-454]
------
S
A
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
---
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
L
T
R
F
K
L
V
I
D
E
L
R
Q
R
E
A
S
GRRMGVIAGAAARLDG
L
G
G
R
V
L
I
V
D
DN
E
R
Q
A
Q
R
V
A
A
E
L
GVE
H
R
P
V
I
E
SD
P
E
K
A
K
I
S
A
G
GPVD
L
V
I
V
N
AAAKNFD
G
L
R
F
T
A
A
L
R
S
E
ERTRQ
L
P
V
L
A
M
V
D
PDD
R
G
R
M
V
K
A
L
E
I
GVN
D
I
L
S
R
PID
P
Q
E
L
S
A
R
V
K
T
Q
I
Q
R
K
R
Y
T
D
Y
L
R
N
NLDHSLELAVTDQLTGLHN
R
R
Y
M
T
G
Q
L
D
S
L
V
K
R
A
T
L
G
G
D
P
V
S
A
L
L
I
D
I
D
F
F
K
K
I
N
D
TFG
H
D
I
G
D
E
V
L
R
E
F
A
L
R
L
A
S
N
V
RAI
D
L
P
C
RYGGE
E
F
V
V
I
M
P
DTA
L
A
D
A
L
R
I
A
E
R
I
R
M
H
V
S
G
S
P
F
T
V
AHGR
E
M
L
N
V
T
I
S
I
G
V
S
A
T
A
G
EGDT
P
E
A
L
L
K
R
A
D
E
G
V
Y
Q
A
K
A
S
GRN
A
V
V
G
K
A
AH
166
HHSearch
86.69
34%
-142
- C2 -
-
4HNR
-
?
A:
[3-117]
-------
A
K
V
L
A
V
D
D
S
I
S
I
R
Q
M
V
S
H
T
L
Q
D
A
G
Y
E
V
E
T
A
A
D
G
R
E
A
L
A
K
A
Q
K
A
R
F
D
V
I
I
S
D
V
N
M
P
V
M
T
G
F
E
F
V
K
A
V
R
M
Q
S
Q
Y
K
F
T
P
I
L
M
L
T
T
E
T
S
P
E
K
K
Q
E
---
G
K
A
V
G
A
T
G
W
L
V
K
P
F
N
P
E
T
L
L
K
T
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
151
HHSearch
85.67
34%
-137
- C2 -
-
3DGE
-
?
C:
[3-119]
-------
K
K
V
L
L
V
D
D
S
A
V
L
R
K
I
V
S
F
N
L
K
K
E
G
Y
E
V
I
E
A
E
N
G
Q
I
A
L
E
K
L
S
E
F
T
P
D
L
I
V
L
D
I
M
M
P
V
M
D
G
F
T
V
L
K
K
L
Q
E
K
E
E
W
K
R
I
P
V
I
V
L
T
A
K
G
G
E
E
D
E
S
L
---
A
L
S
L
G
A
R
K
V
M
R
K
P
F
S
P
S
Q
F
I
E
E
V
K
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
85.08
34%
-142
- C- -
-
3DGF
-
?
C:
[4-118]
--------
K
V
L
L
V
D
D
S
A
V
L
R
K
I
V
S
F
N
L
K
K
E
G
Y
E
V
I
E
A
E
N
G
Q
I
A
L
E
K
L
S
E
F
T
P
D
L
I
V
L
D
I
M
M
P
V
M
D
G
F
T
V
L
K
K
L
Q
E
K
E
E
W
K
R
I
P
V
I
V
L
T
A
K
G
G
E
E
D
E
S
L
---
A
L
S
L
G
A
R
K
V
M
R
K
P
F
S
P
S
Q
F
I
E
E
V
K
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
84.54
33%
-141
- C2 -
-
4HNR
-
?
A:
[4-118]
--------
K
V
L
A
V
D
D
S
I
S
I
R
Q
M
V
S
H
T
L
Q
D
A
G
Y
E
V
E
T
A
A
D
G
R
E
A
L
A
K
A
Q
K
A
R
F
D
V
I
I
S
D
V
N
M
P
V
M
T
G
F
E
F
V
K
A
V
R
M
Q
S
Q
Y
K
F
T
P
I
L
M
L
T
T
E
T
S
P
E
K
K
Q
E
---
G
K
A
V
G
A
T
G
W
L
V
K
P
F
N
P
E
T
L
L
K
T
L
Q
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
156
HHSearch
83.56
34%
-127
- C2 -
-
4H60
-
?
A:
[3-118]
-------
A
K
V
L
A
V
D
D
S
I
S
I
R
Q
M
V
S
H
T
L
Q
D
A
G
Y
E
V
E
T
A
A
D
G
R
E
A
L
A
K
A
Q
K
A
R
F
D
V
I
I
S
D
V
N
M
P
V
M
T
G
F
E
F
V
K
A
V
R
M
Q
S
Q
Y
K
F
T
P
I
L
M
L
T
T
E
T
S
P
E
K
K
Q
E
---
G
K
A
V
G
A
T
G
W
L
V
K
P
F
N
P
E
T
L
L
K
T
L
Q
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.30
41%
-119
- C2 -
-
1MVO
-
PHOP_BACSU
A:
[3-111]
------
N
K
K
I
L
V
V
D
D
E
E
S
I
V
T
L
L
Q
Y
N
L
E
R
S
G
Y
D
V
I
T
A
S
D
G
E
E
A
L
K
K
A
E
T
E
K
P
D
L
I
V
L
D
V
M
L
P
K
L
D
G
I
E
V
C
K
Q
L
R
--
Q
Q
K
L
M
F
P
I
L
M
L
T
A
K
D
E
E
F
D
K
V
L
---
G
L
E
L
G
A
D
D
Y
M
T
K
P
F
S
P
R
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
82.32
40%
-136
- C2 -
-
2ZWM
-
WALR_BACSU
A:
[4-114]
--------
K
I
L
V
V
D
D
E
K
P
I
A
D
I
L
E
F
N
L
R
K
E
G
Y
E
V
H
C
A
H
D
G
N
E
A
V
E
M
V
E
E
L
Q
P
D
L
I
L
L
D
I
M
L
P
N
K
D
G
V
E
V
C
R
E
V
R
K
K
---
Y
D
M
P
I
I
M
L
T
A
K
D
S
E
I
D
K
V
I
---
G
L
E
I
G
A
D
D
Y
V
T
K
P
F
S
T
R
E
L
L
A
R
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
81.61
40%
-138
- C2 -
-
3F6P
-
WALR_BACSU
A:
[4-114]
--------
K
I
L
V
V
D
D
E
K
P
I
A
D
I
L
E
F
N
L
R
K
E
G
Y
E
V
H
C
A
H
D
G
N
E
A
V
E
M
V
E
E
L
Q
P
D
L
I
L
L
D
I
M
L
P
N
K
D
G
V
E
V
C
R
E
V
R
K
K
---
Y
D
M
P
I
I
M
L
T
A
K
D
S
E
I
D
K
V
I
---
G
L
E
I
G
A
D
D
Y
V
T
K
P
F
S
T
R
E
L
L
A
R
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
81.37
33%
-126
- C2 -
-
4H60
-
?
A:
[4-118]
--------
K
V
L
A
V
D
D
S
I
S
I
R
Q
M
V
S
H
T
L
Q
D
A
G
Y
E
V
E
T
A
A
D
G
R
E
A
L
A
K
A
Q
K
A
R
F
D
V
I
I
S
D
V
N
M
P
V
M
T
G
F
E
F
V
K
A
V
R
M
Q
S
Q
Y
K
F
T
P
I
L
M
L
T
T
E
T
S
P
E
K
K
Q
E
---
G
K
A
V
G
A
T
G
W
L
V
K
P
F
N
P
E
T
L
L
K
T
L
Q
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
80.93
33%
-83
- C2 -
-
3LTE
1
?
S:
[5-124]
-----
Q
S
K
R
I
L
V
V
D
D
D
Q
A
M
A
A
A
I
E
R
V
L
K
R
D
H
W
Q
V
E
I
A
H
N
G
F
D
A
G
I
K
L
S
T
F
E
P
A
I
M
T
L
D
L
S
M
P
K
L
D
G
L
D
V
I
R
S
L
R
Q
N
K
-
V
A
N
Q
P
K
I
L
V
V
S
--
G
L
-
D
K
A
K
LQQ
A
V
T
E
G
A
D
D
Y
L
E
K
P
F
D
N
D
A
L
L
D
R
I
H
D
L
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
80.91
39%
-142
- C2 -
-
1NXX
-
?
A:
[3-108]
--------
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
K
E
G
Y
E
V
V
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
----
I
D
G
L
E
V
A
K
T
I
R
K
T
---
S
S
V
P
I
L
M
L
S
A
K
D
S
E
F
D
K
V
I
---
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
80.79
34%
-136
- C2 -
-
3DGE
-
?
C:
[4-118]
--------
K
V
L
L
V
D
D
S
A
V
L
R
K
I
V
S
F
N
L
K
K
E
G
Y
E
V
I
E
A
E
N
G
Q
I
A
L
E
K
L
S
E
F
T
P
D
L
I
V
L
D
I
M
M
P
V
M
D
G
F
T
V
L
K
K
L
Q
E
K
E
E
W
K
R
I
P
V
I
V
L
T
A
K
G
G
E
E
D
E
S
L
---
A
L
S
L
G
A
R
K
V
M
R
K
P
F
S
P
S
Q
F
I
E
E
V
K
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
80.32
35%
-138
- C2 -
-
1W25
-
PLED_CAUCN
A:
[3-117]
--------
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
---
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
162
HHSearch
80.23
28%
-146
- C2 -
-
2JBA
1
PHOB_ECOLI
A:
[3-118]
-------
R
R
I
L
V
V
E
D
E
A
P
I
R
E
M
V
C
F
V
L
E
Q
N
G
F
Q
P
V
E
A
E
D
Y
D
S
A
V
N
Q
L
N
E
P
W
P
D
L
I
L
L
A
W
M
L
P
G
G
S
G
I
Q
F
I
K
H
L
R
R
E
S
M
T
R
D
I
P
V
V
M
L
T
A
R
G
E
E
E
D
R
V
R
---
G
L
E
T
G
A
D
D
C
I
T
K
P
F
S
P
K
E
L
V
A
R
I
K
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
80.01
31%
-134
- C2 -
-
4QPJ
1
CTRA_BRUA2
C:
[34-147]
------
S
M
R
V
L
L
I
E
D
D
S
A
I
A
Q
S
I
E
L
M
L
K
S
E
S
F
N
V
Y
T
T
D
L
G
E
E
G
I
D
L
G
K
L
Y
D
Y
D
I
I
L
L
D
L
N
L
P
D
M
S
G
Y
E
V
L
R
T
L
R
L
S
K
--
V
K
T
P
I
L
I
L
S
G
M
A
G
I
E
D
K
V
R
---
G
L
G
F
G
A
D
D
Y
M
T
K
P
F
H
K
D
E
L
I
A
R
I
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
79.79
35%
-134
- C2 -
-
2WB4
1
PLED_CAUCN
A:
[4-118]
--------
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
---
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
79.74
35%
-135
- C2 -
-
2V0N
-
PLED_CAUCN
A:
[3-117]
--------
R
I
L
V
V
D
D
I
E
A
N
V
R
L
L
E
A
K
L
T
A
E
Y
Y
E
V
S
T
A
M
D
G
P
T
A
L
A
M
A
A
R
D
L
P
D
I
I
L
L
D
V
M
M
P
G
M
D
G
F
T
V
C
R
K
L
K
D
D
P
T
T
R
H
I
P
V
V
L
I
T
A
L
D
G
R
G
D
R
I
Q
---
G
L
E
S
G
A
S
D
F
L
T
K
P
I
D
D
V
M
L
F
A
R
V
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
159
HHSearch
79.50
27%
-155
- C2 -
-
3NHM
-
?
B:
[19-133]
-------
P
K
V
L
I
V
E
N
S
W
T
M
R
E
T
L
-
R
L
L
L
S
G
E
F
D
C
T
T
A
A
D
G
A
S
G
L
Q
Q
A
L
A
H
P
P
D
V
L
I
S
D
V
N
M
D
G
M
D
G
Y
A
L
C
G
H
F
R
S
E
P
T
L
K
H
I
P
V
I
F
V
S
G
Y
A
-
P
--------
A
D
Q
P
V
P
D
A
Y
L
V
K
P
V
K
P
P
V
L
I
A
Q
L
H
A
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
78.65
39%
-122
- C2 -
-
2A9P
-
?
A:
[3-108]
--------
K
I
L
I
V
D
D
E
K
P
I
S
D
I
I
K
F
N
M
T
K
E
G
Y
E
V
V
T
A
F
N
G
R
E
A
L
E
Q
F
E
A
E
Q
P
D
I
I
I
L
D
L
M
L
P
E
I
D
G
L
E
V
A
K
T
I
R
K
T
---
S
S
V
P
I
L
M
L
S
A
K
D
S
E
F
D
K
V
I
---
G
L
E
L
G
A
D
D
Y
V
T
K
P
F
S
N
R
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------