@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSB4: (2017-12-07 )
MNFIKKWSVGLLSMLPVLAMAHPGHDHVHSGFMAGFIHPFTGLDHLIMALGFGVLLWSAAKQWKIAGVITLSITLVIGFLVGAQGLVPANVAEYGIVTSLIITAIALWTKSNRILPIAAALLASFHGMAHGVELAHAGHIVALVTGMVAGMALIYCGGLALGAVFTRYVPYGKKIVGACAALVAVIGLS
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------......-----...10......-..20....-----...---.-30.....--...---40-----------...-.....--50---.----------.......---.60...-..---..----.70....----.-----...80-.--.-.------......90--........100.....--..110.......120....-...130....----..-.140.......-150..-.....160.......170.......180.......--------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN
F
I
K
K
-----
W
S
V
G
L
L
S
M
L
P
V
-
L
A
MAHPG
H
-----
D
H
V
---
H
-
S
G
F
M
A
G
F
--IHP---FT-----------
G
L
D
-
H
L
I
M
A
--
L
----
G
----------
F
G
V
L
L
W
S---AAK
Q
W
K
-
I
A
---
G
V
----
I
T
L
S
I
T
L
----
V
-----
I
G
F
L
--V--G-A------QGLVP
A
N
V
--
A
E
Y
G
I
V
T
S
L
I
I
T
A
I
A
L
--WTKSNR
I
L
P
I
A
A
A
L
L
A
S
F
H
-
G
MAH
G
V
ELAH----A
G
-
H
I
V
A
L
V
T
G
M
V
A
-
G
M
A
L
I
-
Y
CG
G
L
A
L
G
A
V
F
T
R
YVPY
G
K
K
I
V
G
A
C
A
A
L
V
A
V
IGLS--------------------------------------------------------------------------------------------------------------
26
Fugue
73.29
19%
-70
- C9 -
-
5LQJ
1
COMT_RAT
A:
[3-216]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DT
K
E
Q
R
I
L
R
Y
V
Q
Q
N
AKPG
D
P
Q
S
V
L
E
A
I
D
T
-
Y
C
T
Q
K
E
W
A
-----
M
N
V
G
D
A
K
-
G
Q
I
M
D
A
V
--
I
R
E
---
Y
S
PS
L
V
L
E
L
G
AYC
G
Y
S
-
A
V
R
M
A
R
L
L
----
Q
----------
P
G
A
R
L
L
T
---
M
E
I
N
P
D
-
C
A
---
A
I
----
T
Q
Q
M
L
N
F
----
A
GLQDK
V
T
I
L
--
N
--
G
A
S
------
Q
D
L
I
P
Q
L
K
--
K
K
Y
D
-
V
D
T
L
D
M
V
F
L
D
H
--
W
--
K
D
R
Y
L
P
D
T
L
L
L
E
K
--
C
-
G
L
L
R
K
G
T
V
L
L
----
A
D
-
N
V
I
V
P
--
G
T
P
D
-
F
L
A
Y
V
-
R
G
S
S
S
F
E
C
T
H
Y
S
S
Y
L
E
Y
M
K
V
V
D
G
L
E
K
A
I
Y
Q
--
G
P
S
--------------------------------------------------------------------------------------------------------------
22
Fugue
67.78
20%
-89
- C5 -
-
1JXP
-
POLG_HCVBK
A:
[3-179]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
A
-----
Y
S
Q
Q
T
R
G
L
L
G
C
-
I
I
T
S
L
T
G
R
-----
D
K
N
---
Q
-
V
---
E
G
E
--
V
Q
V
---
V
S
-----------
T
A
T
-
Q
S
F
L
A
--
T
----
C
----------
V
N
G
V
C
W
T
V
YH
G
A
G
S
K
T
-
L
A
GPK
G
P
----
I
T
Q
M
Y
T
N
VDQD
L
-----
V
G
W
Q
--
A
PP
G
-
A
------
R
S
L
T
P
C
T
C
GS
S
D
L
Y
L
V
T
R
H
A
D
V
I
P
V
R
--
R
R
G
D
S
R
G
S
L
L
S
P
R
P
V
S
Y
L
K
-
G
S
S
G
G
P
L
L
C
P
----
S
G
-
H
A
V
G
I
F
R
A
A
V
C
-
T
-------
R
G
V
A
K
A
V
D
F
V
P
V
E
S
M
E
T
T
M
----------------------------------------------------------------------------------------------------------------------------
20
Fugue
67.43
21%
-85
* C9 *
-
5TXE
-
?
A:
[35-686]
APPVT
P
E
V
L
V
R
L
A
D
I
G
TMSASETTPL
L
S
L
S
PDGR
Y
V
A
F
Q
V
R
Q
A
D
PVTN
L
N
V
F
R
M
V
V
K
A
TDGATDAIDV
D
V
G
G
E
YLFW
T
I
P
S
WGYARNAPSGANL
T
I
Q
P
R
W
S
PSGT
H
L
A
Y
L
R
Q
D
QG
R
V
R
V
W
R
A
S
VKGE
G
A
S
P
VIEDAYDIE
D
V
Q
W
LDDN
T
L
I
Y
S
G
R
P
G
F
V
E
A
E
A
E
I
E
R
E
G
R
R
GWVYDERFHPLTGARPRVLEP
I
S
I
V
Y
Q
V
L
DLKTG
T
R
R
A
A
T
P
T
E
V
A
R
L
R
EKPDPL
R
A
M
V
GR
T
T
F
S
V
S
R
TDPQNINA
P
T
T
L
V
A
R
RGEG
E
P
V
R
C
DEEACQNIT
R
M
W
G
D
ETAN
V
L
Y
F
L
R
R
E
G
WASN
E
M
A
L
Y
R
M
PADAL
K
P
V
R
I
W
H
A
T
G
LLQG
C
E
R
Q
AK
R
L
I
C
A
Q
E
S
ALQ
P
R
R
L
V
T
L
N
LTSG
Q
M
S
P
LYDPNPDLSRYRL
P
K
V
E
R
L
T
L
R
N
RNG
I
E
V
F
S
D
L
V
L
P
P
D
-----
Y
Q
L
G
--
T
R
L
P
L
-
V
I
V
Q
Y
S
S
R
------------------
G
F
--
L
R
G
---
G
T
-----------
G
D
E
-
N
P
I
L
P
--
L
----
A
T
A
G-------
F
A
V
L
S
F
H
---
S
P
R
S
E
A
-
S
Y
---
Q
R
----
F
T
S
-----------------
P
--
I
--
A
-
Q
------
S
K
A
E
Y
S
N
W
--
R
N
R
W
N
I
L
H
T
L
E
D
L
I
D
D
--
L
D
R
R
G
V
I
D
P
A
R
V
G
L
T
G
-----
L
A
D
G
A
T
T
V
H
----
F
G
-
L
I
N
S
--
H
R
F
A
A
-
A
V
T
S
S
-
C
C
T
D
-----
S
F
T
A
S
V
M
N
G
P
R
I
S
G
A
L
K
A
Y
----
G
I
E
TDQADDGPFWAATSFVVNASRLD
T
P
L
L
I
QSADEEYLGAL
P
G
F
T
A
L
Q
Q
A
RKP
V
E
L
I
I
Y
P
NEHHVKWQ
P
A
H
R
L
A
V
Y
N
R
T
I
D
W
F
R
F
W
LMDQSDPAPDK
A
A
Q
Y
D
R
W
R
A
L
R
A
L
R
Q
3
PsiBlast_PDB
60.57
22%
-81
- C8 -
-
4OJY
2
?
A:
[250-354]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-----
I
P
I
---
T
-
T
N
F
M
A
D
T
HD
L
I
P
---
F
Q
-----------
G
L
D
-
Y
S
K
F
A
--
K
----
H
----------
L
D
V
I
S
W
D
---
A
Y
P
A
W
H
-
N
D
---
W
E
----
S
T
A
D
L
A
M
----
K
-----
V
G
F
I
---------------
N
D
L
Y
R
S
L
--
K
Q
Q
P
F
L
L
M
E
C
T
P
S
L
V
N
--
W
H
K
V
N
K
A
K
R
P
G
M
H
F
L
S
S
M
Q
-
M
I
A
H
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.54
22%
-76
- C8 -
-
4OIF
3
?
A:
[249-353]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-----
I
P
I
---
T
-
T
N
F
M
A
D
T
HD
L
I
P
---
F
Q
-----------
G
L
D
-
Y
S
K
F
A
--
K
----
H
----------
L
D
V
I
S
W
D
---
A
Y
P
A
W
H
-
N
D
---
W
E
----
S
T
A
D
L
A
M
----
K
-----
V
G
F
I
---------------
N
D
L
Y
R
S
L
--
K
Q
Q
P
F
L
L
M
E
C
T
P
S
L
V
N
--
W
H
K
V
N
K
A
K
R
P
G
M
H
F
L
S
S
M
Q
-
M
I
A
H
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
57.34
15%
-40
- C4 -
-
5GOX
2
RAD50_HUMAN
A:
[5-185]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
I
N
Q
-----
T
R
D
R
L
A
K
L
N
K
E
-
L
A
S
S
E
Q
N
K
-----
N
H
I
---
N
-
N
E
L
K
R
K
E
--
E
Q
L
---
S
S
-----------
Y
E
D
-
K
L
F
D
V
--
C
----
G
SQDF
E
S
D
L
D
R
L
K
E
E
I
E
K
---
S
S
K
Q
R
A
M
L
A
---
G
A
----
T
A
V
Y
S
Q
F
----
I
-----
T
Q
L
T
--
D
--
E
-
N
------
Q
S
C
C
P
--
V
--
C
Q
R
V
F
Q
T
E
A
E
L
Q
E
V
I
S
--
D
L
Q
S
K
--
L
R
L
A
P
D
K
L
K
S
T
E
-
S
E
L
K
K
K
E
K
R
R
----
D
E
M
L
------
G
L
V
P
M
R
Q
S
I
I
-
D
L
K
E
K
E
I
P
E
L
R
N
K
L
Q
N
V
N
R
D
I
Q
R
L
K
------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
56.71
26%
-142
- C8 -
-
4ATQ
2
?
A:
[226-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-
V
A
---
A
I
----
I
I
E
P
I
Q
G
----
E
-----
G
G
F
I
--
V
--
P
-
A
------
E
G
F
L
P
-----------------
A
L
S
E
--
W
A
K
E
K
G
I
V
F
I
A
D
E
V
Q
S
G
F
C
-
R
T
G
E
W
F
A
V
D
H
----
E
G
-
V
V
P
D
I
I
T
-
M
A
K
-
G
I
A
-----
G
G
L
P
L
S
A
I
T
G
R
------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
56.30
26%
-142
- C8 -
-
4ATP
1
?
A:
[226-314]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-
V
A
---
A
I
----
I
I
E
P
I
Q
G
----
E
-----
G
G
F
I
--
V
--
P
-
A
------
E
G
F
L
P
-----------------
A
L
S
E
--
W
A
K
E
K
G
I
V
F
I
A
D
E
V
Q
S
G
F
C
-
R
T
G
E
W
F
A
V
D
H
----
E
G
-
V
V
P
D
I
I
T
-
M
A
K
-
G
I
A
-----
G
G
L
P
L
S
A
I
T
G
R
------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
55.99
22%
-
- C1 -
-
4Q28
-
PEPL_HUMAN
A:
[1645-1754]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
H
H
H
H
-----
H
H
S
---
H
M
R
R
S
I
V
-
V
--
I
H
P
---
D
T
-----------
G
R
E
L
S
P
E
E
A
--
H
----
R
----------
A
G
L
I
D
W
N
M
--
F
V
K
L
R
S
-
Q
E
-------------------------------------------------
C
D
W
--
E
E
I
S
V
K
G
P
N
G
E
S
S
V
I
H
--
D
R
K
S
G
K
K
F
S
I
E
E
A
L
Q
S
G
R
L
-
T
P
A
Q
Y
D
R
Y
V
N
KDMS
I
Q
-
E
L
A
V
L
V
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
55.56
22%
-91
- C8 -
-
5DFA
2
?
A:
[249-353]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-----
I
P
I
---
T
-
T
N
F
M
A
D
T
HD
L
I
P
---
F
Q
-----------
G
L
D
-
Y
S
K
F
A
--
K
----
H
----------
L
D
V
I
S
W
D
---
A
Y
P
A
W
H
-
N
D
---
W
E
----
S
T
A
D
L
A
M
----
K
-----
V
G
F
I
---------------
N
D
L
Y
R
S
L
--
K
Q
Q
P
F
L
L
M
A
C
T
P
S
L
V
N
--
W
H
K
V
N
K
A
K
R
P
G
M
H
F
L
S
S
M
Q
-
M
I
A
H
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
53.81
35%
0
- C- -
-
5IJO
-
NU188_HUMAN
J:
[618-996]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
V
-
L
A
A
R
N
P
A
K
VWT--
D
L
R
---
H
-
T
G
F
L
P
F
V
--
A
H
-----------------------------MNAG
G
----------
Y
G
N
L
L
M
N
---
S
E
Q
P
Q
G
-
E
Y
---
G
V
TIAF
L
R
L
I
T
T
L
----
V
-----
K
G
Q
L
GS
T
--
Q
-
S
------
Q
G
L
V
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
52.92
17%
-43
- C6 -
-
5KCI
1
YP067_YEAST
A:
[16-199]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GWK
W
E
Q
I
K
E
I
-----
I
E
S
G
E
L
A
R
L
K
R
S
R
Q
M
T
D
K
Y
H
-----
E
H
K
---
K
-
R
T
--------
A
G
---
L
D
-----------
M
N
Q
-
Y
V
L
Q
K
--
L
----
G
---------------
W
S
---
L
D
E
P
-
Q
-
L
E
---
N
A
----
A
A
K
A
F
S
S
----
S
-----
T
L
Y
A
--
V
--
R
-
A
------
N
D
F
-
P
Y
N
F
---
E
P
G
V
V
H
L
V
L
W
S
K
V
A
L
PV
H
S
P
D
K
A
V
R
E
A
A
R
A
R
M
N
A
F
L
Q
A
Q
P
L
L
R
P
L
L
S
----
S
G
-
H
V
A
W
F
V
N
--
Y
P
-
E
L
Q
S
V
-
A
R
I
F
H
A
H
V
L
L
F
F
P
R
E
R
Y
S
A
E
Q
V
K
T
T
V
D
D
I
L
S
H
G
F
E
P
L
A-----------------------------------------------------------------------------------------------------------
24
Fugue
48.26
18%
-25
- C2 -
-
4CUA
7
?
A:
[4-181]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QG
A
N
I
S
D
Q
-----
W
T
---
G
S
E
L
P
--
L
A
F
A
S
D
S
N
PSDPV
S
N
V
---
N
-
D
K
L
I
S
Y
N
--
N
Q
P
A
N
R
W
T
-----------
N
W
N
-
R
S
N
P
E
--
A
----
S
----------
V
G
V
L
-
F
G
---
D
S
G
I
L
S
-
K
R
---
S
V
----
D
N
L
S
V
G
F
----
H
-----
E
D
H
G
--
V
--
G
-
A
PK
S
Y
V
I
E
Y
Y
V
G
K
T
V
--
P
T
A
P
K
N
P
S
F
V
G
N
E
D
H
V
--
F
N
D
S
A
N
W
K
P
V
T
---------
N
L
K
A
P
A
Q
L
K
A
----
G
E
M
N
H
F
S
F
D
K
V
E
T
Y
-
A
I
R
I
R
M
V
K
A
D
N
K
R
G
T
S
I
T
E
V
Q
I
F
A
K
------------------------------------------------------------------------------------------------------------------------------
19
Fugue
38.73
42%
-61
- C3 -
-
1JY9
-
?
A:
[1-20]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
T
T
R
Y
V
E
V
G
K
K
I
L
Q
T
T
T
T
----------------------------------------------------------------------------------------------------------------------
11
HHSearch
33.18
39%
-154
- C7 -
-
4N0Q
-
LIVB3_BRUME
B:
[9-24]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
I
T
I
G
V
--
I
A
P
---
L
T
-----------
G
P
V
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
31.53
35%
-199
* C8 *
-
2LX0
-
?
A:
[9-28]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
-----------
G
L
V
-
A
L
L
T
F
--
L
----
A
----------
F
G
F
W
L
F
K
---
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
29.49
39%
-64
* C7 *
-
4N0Q
-
LIVB3_BRUME
A:
[10-24]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
T
I
G
V
--
I
A
P
---
L
T
-----------
G
P
V
-
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
28.50
23%
-44
- C8 -
-
2M1N
-
?
B:
[57-69]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
E
-
G
Y
T
Y
G
E
E
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
15.11
23%
129
- C8 -
-
1XOU
-
?
B:
[57-69]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
E
-
G
Y
T
Y
G
E
E
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
0.61
13%
-
- C7 -
-
2JNA
-
?
A:
[1-23]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
R
I
I
-----
A
A
A
L
L
A
T
V
A
S
F
-
S
T
L
A
A
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------