@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSG0: (2017-12-07 )
MSMSFDLKVSLQQRSEPSAQQKKLNRLIDKIEQQKVSLSTWQNAQAEIQQHMRQKLMPVYNDLHTVLFQQLEQLWNILHSHEFSKADIQQLDEKIAQLAQMLKRSKMLSAEQLELVKQIDTFYQQHAGESVKKNKKVQPIKSEYEESVDQRAELEEEFEKYAAEQQQAREQAKQQRQQQKREQAEQMAAQSLKTVYLKIAAMIHPDGEQDETKKYEKNELFQQASQAYEKQDLFYLLKLQLQLEQNKGLGAKELSAEQLRFYKLALDAQSQQLESQIAEILDSFQLAKNIKAEHVHISDVYKAIDADCAELKQQLKWERERLKHMKKVSVVEMLLGHGVL
Atome Classification :
(20 SA)
----------------------------...-------......10......-----..20------------........30.....-...40.-..-.....50.--..-.....60-----........70.--.......80....-....90.-------.......100.......110.....-..--120......--.130.......140.......150.......160.......170....----...180.......-----------------------------------------------190...------....200------........210--....---------...220.......230.......240-------........250.......260.......270...-----....280----..-.......290..-------.....300-------.........310.......320.......330....-----...340------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------MSM-------
S
F
D
L
K
V
S
LQQRSEP-----
S
A
Q
Q
------------
K
K
L
N
R
L
I
D
K
I
E
Q
QKV-SL
S
T
W
Q
-
N
A
-
Q
A
E
I
Q
Q
H
M
--
R
Q
-
K
L
M
P
V
Y
N
-----
D
L
H
T
V
L
F
Q
Q
L
E
--
Q
L
W
N
I
L
H
SHEF
S
K
-
A
D
I
Q
Q
L
D
-------
E
K
I
A
Q
L
A
Q
M
L
K
R
S
KML
S
A
E
Q
L
E
L
V
K
-
Q
I
--
D
T
F
Y
Q
Q
HAG--
E
S
V
KKNKKVQ
P
I
K
S
E
Y
E
E
S
V
D
Q
R
A
E
L
E
E
E
F
E
K
Y
A
A
E
Q
Q
Q
A
R
E
Q
A
K
Q
Q
R
----
Q
Q
Q
K
R
E
Q
A
E
Q
M
A
A
-----------------------------------------------
Q
S
L
K
T
V
------
Y
L
K
I
A
A
-------
M
IHPDGE
Q
D
E
T
--
K
K
Y
E
---------
K
N
E
L
F
Q
Q
A
S
Q
A
Y
E
K
Q
D
L
F
Y
L
L
K
L
Q
L
--------
Q
L
EQNKGLGAKEL
S
A
E
Q
L
R
F
Y
K
L
ALD
A
Q
S
Q
Q
L
E
S
-----
Q
I
A
E
I
------
L
D
-
S
F
Q
L
A
K
NIKAE
H
-------
V
H
I
S
D
V
---------
Y
K
A
IDA
D
C
A
E
L
K
Q
Q
L
K
W
E
R
E
R
L
K
H
M
K
K
V
S
V
V
E
M
L
LG-----HGVL--------------------------
43
Fugue
65.06
19%
61
- C2 -
-
4MT0
-
?
A:
[1-445]
----------------------------
C
T
M
IP
Q
Y
E
Q
P
K
V
E
V
A
E
T
F
Q
N
D
T
S
V
-----
S
S
I
R
AVDLG
W
H
D
Y
F
AD
P
R
L
Q
K
L
I
D
I
A
L
E
R
N
T
-
S
L
R
T
A
V
L
N
S
-
E
I
Y
R
K
Q
Y
M
I
E
R
N
-
N
L
L
P
T
L
A
-----
A
N
A
N
G
S
R
Q
G
S
L
--
S
G
G
N
V
S
S
S
Y
N
V
G
L
G
A
A
S
Y
E
L
D
LFG
R
V
R
S
S
S
E
A
A
L
Q
G
Y
F
A
S
V
A
N
R
D
A
A
H
L
S
L
I
A
-
T
V
A
K
A
Y
F
N
E
R
Y
A
E
--
E
A
M
S
L
A
Q
R
V
L
K
T
R
E
E
T
Y
N
A
V
R
I
A
V
Q
G
R
R
D
F
R
R
R
P
A
P
A
E
A
L
I
E
S
A
K
A
D
Y
----
A
H
A
A
R
S
R
E
Q
A
R
N
A
L
A
T
L
I
NRPIPEDLPAGLPLDKQFFV
E
K
L
P
AGL
S
S
E
V
L
L
D
R
P
D
I
R
A
A
E
H
A
L
K
Q
A
------
N
A
N
I
G
A
A
R
A
A
F
F
P
S
I
R
L
T
G
S
V
G
-
T
--
G
S
V
E
---------
L
G
G
L
F
K
S
G
T
G
V
W
A
F
A
P
S
I
T
L
P
I
F
T
W
--------
G
T
N
K
A
N
L
D
V
A
K
L
R
Q
Q
A
Q
I
V
A
Y
E
S
A
V
Q
S
A
F
Q
D
V
A
N
-----
A
L
A
A
R
E
Q
L
D
K
A
Y
D
-
A
L
S
K
Q
S
R
A
S
K
E
A
-------
L
R
L
V
G
L
R
Y
K
HGVSGA
L
D
L
L
D
A
E
R
S
S
Y
S
A
E
G
A
A
L
S
A
Q
L
T
R
A
E
N
L
A
D
L
Y
K
A
L
G
-----
G
G
L
K
RDTQT---------------------
12
PsiBlast_PDB
52.29
23%
-67
- C5 -
-
4YKN
-
P85A_HUMAN (first)
A:
[168-344]
--------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
K
R
-
T
A
I
E
A
F
N
-------
E
T
I
K
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
-
R
-------
E
G
N
E
K
--
E
I
Q
R
I
M
H
N
Y
D
K
L
K
S
R
I
S
E
I
I
D
S
R
R
R
L
E
E
D
L
K
K
Q
A
A
E
Y
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
51.72
19%
-155
- C5 -
-
1VDF
-
COMP_RAT
A:
[1-46]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
L
A
P
Q
M
L
R
E
L
Q
E
T
N
A
A
L
Q
D
V
R
E
L
L
R
Q
Q
V
----
K
E
I
T
F
L
K
N
T
V
M
E
C
-----------------------------------------------
D
A
C
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
51.12
12%
49
* C4 *
-
4B28
-
DDDP_ROSDO
A:
[32-468]
RKIDPSRGATLGDGSPNDMNRVEIGPT
Q
L
A
F
-------
A
E
W
H
T
A
R
L
D
L
P
D
L
A
-----
A
M
R
R
------------
F
R
H
R
R
L
T
D
H
V
V
A
R
G
Y
A
G
L
L
M
F
D
-
P
L
-
N
I
R
Y
A
T
D
S
--
T
N
M
Q
L
W
N
T
H
N
-----
P
F
R
A
T
L
L
C
A
D
G
Y
M
V
M
W
D
Y
K
N
S
P
F
L
S
E
-
F
N
P
L
V
R
E
-------
Q
R
A
G
A
D
L
F
Y
F
D
R
G
D
K
V
D
V
A
A
D
V
F
A
N
-
E
V
--
R
I
L
L
R
D
H
A
P
GL
R
R
L
A
V
D
K
V
M
L
H
G
L
R
A
L
Q
A
Q
G
F
E
I
M
D
G
E
E
V
T
E
K
A
R
S
V
K
G
P
D
E
I
R
A
M
R
C
A
----
S
H
A
C
E
V
A
V
R
K
M
E
D
-----------------------------------------------
F
A
R
S
K
V
GDGVTC
E
N
D
I
W
A
-------
I
L
H
S
E
N
V
R
R
G
G
--
E
W
I
E
TRLLASGPR
S
N
P
W
F
Q
E
C
G
P
R
V
C
Q
R
N
E
I
I
S
F
D
T
D
L
VGAYG
I
C
T
D
I
S
R
S
W
W
I
G
D
Q
K
P
R
A
D
M
I
Y
A
M
Q
H
G
V
E
H
I
R
T
N
M
E
M
LKPGV
M
I
P
E
L
------
S
A
N
T
H
V
L
D
A
K
F
Q
K
Q
K
YGCL
M
H
G
V
G
L
C
D
E
---------
W
P
L
V
A
--
Y
P
D
H
A
V
A
G
A
Y
D
Y
P
L
E
P
G
M
--
T
L
C
V
E
A
L
I
S
E
EGGD
F
S
I
K
L
E
D
Q
V
L
I
T
ED
G
Y
E
N
LTKYPFDPALMG
14
PsiBlast_PDB
50.97
24%
-48
- C5 -
-
5M6U
-
P85A_HUMAN
B:
[478-558]
--------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
K
R
-
T
A
I
E
A
F
N
-------
E
T
I
K
I
F
E
E
Q
C
Q
T
Q
E
R
Y
S
K
E
Y
I
E
K
F
K
-
R
-------
E
G
N
E
T
--
E
I
Q
R
I
M
H
N
Y
E
K
L
K
S
R
I
S
E
I
V
D
S
R
R
R
L
E
E
D
L
K
K
Q
A
A
E
Y
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
48.64
17%
6
- C3 -
-
2W18
5
A:
[24-356]
--------------------------------------
N
L
Q
L
V
S
E
L
K
N
P
S
G
S
C
S
V
D
V
S
A
M
F
------------
W
E
K
E
P
C
I
I
T
A
C
E
D
V
V
-
S
L
W
K
A
L
-
D
A
W
Q
W
E
K
L
Y
T
W
--
H
F
-
A
E
V
P
V
L
Q
I
V
P
V
P
D
V
Y
N
L
V
C
V
A
L
G
--
N
L
-
E
I
R
E
I
R
A
L
F
C
-
E
K
Q
V
L
L
K
-------
S
G
N
I
K
A
V
L
G
L
T
K
R
R
L
V
S
S
S
G
T
L
S
D
Q
-
Q
V
--
E
V
M
T
F
A
E
D
G
---
G
G
K
E
N
Q
F
L
M
P
P
----
E
E
T
I
L
T
F
A
E
V
Q
G
M
Q
E
A
L
L
G
T
T
I
M
---------------------
N
N
I
V
I
-----------------------------------------------
W
N
L
K
T
G
------
Q
L
L
K
K
M
-------
H
I
D
D
A
S
--------------------------
V
C
H
K
A
Y
S
E
M
G
L
L
F
I
V
L
S
P
V
----------
F
Q
L
I
V
I
N
P
K
T
T
L
S
V
G
V
M
L
Y
C
L
P
P
G
Q
A
G
R
F
L
E
G
-----
D
V
K
D
-----------
H
C
A
A
A
I
L
T
S
G
T
-------
I
A
I
W
D
L
---------
L
--
L
G
Q
C
T
A
L
L
P
P
V
Q
H
W
S
F
V
K
W
S
G
T
D
S
H
L
L
A
G
Q
K
D
G
-----
N
I
F
V
Y
H
Y
S----------------------
28
HHSearch
46.65
22%
0
* C5 *
-
2QSA
-
DNJ2_CAEEL
A:
[29-86]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
-----------------------------------------------
Q
K
L
A
K
A
------
Y
R
A
L
A
R
-------
K
H
H
P
D
R
V
K
N
K
E
--
E
K
L
L
---------
A
E
E
R
F
R
V
I
A
T
A
Y
E
T
L
K
D
D
E
A
K
T
N
Y
D
--------
Y
Y
L
D
----------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.44
26%
-106
- C5 -
-
2GDR
-
?
A:
[93-177]
---------------------------------------------------------------------------------------------------------
H
L
--
Q
Q
-
W
L
N
F
I
S
S
-----
E
L
H
----
K
S
F
S
--
P
L
F
N
P
A
S
S
D
E
W
K
N
-
A
V
R
Q
S
L
N
-------
T
R
L
G
Q
V
A
R
Q
L
E
H
A
P
Y
L
L
G
D
Q
L
S
V
A
------
D
I
Y
L
F
V
V
L
G
--
W
S
A
Y
V
N
I
D
L
S
P
W
P
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
45.44
26%
-119
- C5 -
-
2DSA
1
?
A:
[93-177]
---------------------------------------------------------------------------------------------------------
H
L
--
Q
Q
-
W
L
N
F
I
S
S
-----
E
L
H
----
K
S
F
S
--
P
L
F
N
P
A
S
S
D
E
W
K
N
-
A
V
R
Q
S
L
N
-------
T
R
L
G
Q
V
A
R
Q
L
E
H
A
P
Y
L
L
G
D
Q
L
S
V
A
------
D
I
Y
L
F
V
V
L
G
--
W
S
A
Y
V
N
I
D
L
S
P
W
P
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
44.04
20%
-45
- C5 -
-
4J7Z
-
DNAJ2_THET8
A:
[16-70]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
Q
-----------------------------------------------
E
E
I
K
R
A
------
Y
K
R
L
A
R
-------
Q
Y
H
P
D
V
N
K
S
P
------
E
---------
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
--------
T
Y
G
T
----------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
42.19
27%
-5
- C5 -
-
2DMX
-
DNJB8_HUMAN
A:
[22-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
-----------------------------------------------
E
D
I
K
K
A
------
Y
R
K
L
A
L
-------
R
W
H
P
D
K
N
P
D
N
K
----
E
E
---------
A
E
K
K
F
K
L
V
S
E
A
Y
E
V
L
S
D
S
K
K
R
S
L
Y
D
--------
R
A
G
C
----------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
42.02
26%
59
- C5 -
-
5IJO
-
NUP62_HUMAN
H:
[337-436]
------------------------------------------------------------------------------------------
I
N
K
W
S
-
L
E
-
L
E
D
Q
E
R
H
F
--
L
Q
-
Q
A
T
Q
V
-
N
-----
A
W
D
R
T
L
I
E
N
G
E
--
K
I
T
S
L
H
R
E
V
E
K
V
K
-
L
D
Q
K
R
L
D
-------
Q
E
L
D
F
I
L
S
Q
Q
K
E
L
E
D
L
L
S
P
L
E
E
L
V
K
E
Q
S
--
G
T
I
Y
L
Q
H
A
D
--
E
E
R
E
K
T
Y
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
42.02
26%
59
- C5 -
-
5IJN
-
NUP62_HUMAN
H:
[337-436]
------------------------------------------------------------------------------------------
I
N
K
W
S
-
L
E
-
L
E
D
Q
E
R
H
F
--
L
Q
-
Q
A
T
Q
V
-
N
-----
A
W
D
R
T
L
I
E
N
G
E
--
K
I
T
S
L
H
R
E
V
E
K
V
K
-
L
D
Q
K
R
L
D
-------
Q
E
L
D
F
I
L
S
Q
Q
K
E
L
E
D
L
L
S
P
L
E
E
L
V
K
E
Q
S
--
G
T
I
Y
L
Q
H
A
D
--
E
E
R
E
K
T
Y
K
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
41.87
26%
-7
- C5 -
-
2CUG
-
DJC16_MOUSE
A:
[30-83]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
-----------------------------------------------
A
D
I
K
K
A
------
Y
K
K
L
A
R
-------
E
W
H
P
D
K
N
K
D
P
------
G
---------
A
E
D
R
F
I
Q
I
S
K
A
Y
E
I
L
S
N
E
E
K
R
T
N
Y
D
--------
H
Y
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
40.88
38%
-36
- C5 -
-
2M6Y
-
DNJA1_HUMAN
A:
[28-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
-----------------------------------------------
E
E
L
K
K
A
------
Y
R
K
L
A
L
-------
K
Y
H
P
D
K
N
P
N
E
-----------------
G
E
K
F
K
Q
I
S
Q
A
Y
E
V
L
S
D
A
K
K
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
40.71
24%
-10
- C5 -
-
2CTP
-
A:
[19-73]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
D
-----------------------------------------------
E
D
L
K
K
A
------
Y
R
R
L
A
L
-------
K
F
H
P
D
K
N
H
A
P
------
G
---------
A
T
E
A
F
K
A
I
G
T
A
Y
A
V
L
S
N
P
E
K
R
K
Q
Y
D
--------
Q
F
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
40.68
37%
-26
- C5 -
-
2LO1
-
DNJA1_HUMAN
A:
[19-67]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
-----------------------------------------------
E
E
L
K
K
A
------
Y
R
K
L
A
L
-------
K
Y
H
P
D
K
N
P
N
E
-----------------
G
E
K
F
K
Q
I
S
Q
A
Y
E
V
L
S
D
A
K
K
R
E
L
Y
D
--------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
40.66
17%
11
- C5 -
-
3BVO
-
HSC20_HUMAN
A:
[59-118]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-----------------------------------------------
A
K
L
Q
H
R
------
Y
Q
Q
L
Q
R
-------
L
V
H
P
D
F
F
S
Q
R
S
Q
T
E
K
D
F
---------
S
E
K
H
S
T
L
V
N
D
A
Y
K
T
L
L
A
P
L
S
R
G
L
Y
L
--------
L
K
L
H
G
---------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
39.10
22%
-27
- C5 -
-
1BQZ
-
DNAJ_ECOLI
A:
[16-70]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
-----------------------------------------------
R
E
I
R
K
A
------
Y
K
R
L
A
M
-------
K
Y
H
P
D
R
N
Q
G
D
K
-----
E
---------
A
E
A
K
F
K
E
I
K
E
A
Y
E
V
L
T
D
S
Q
K
R
A
A
Y
D
--------
Q
Y
G
H
----------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
39.02
28%
69
- C5 -
-
3FPP
-
MACA_ECOLI
A:
[80-154]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
D
K
V
K
K
D
Q
L
L
G
V
I
D
P
E
Q
A
E
--
N
Q
I
K
E
V
E
A
T
L
M
E
L
R
A
Q
R
Q
Q
A
E
A
E
L
K
L
A
R
V
T
Y
S
R
Q
Q
R
L
A
Q
T
Q
A
V
S
Q
-----------------------------------------------
Q
D
L
D
N
A
------
A
T
E
M
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------