@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSK5: (2017-12-08 )
MGAINPKEDYSNIQNLTFDAVIVGGGGSGMRASYQLAQAGLKVAVLTKVFPTRSHTVAAQGGIGASLGNMQEDNWHFHFYDTVKGSDWLGDQDAIEFMCREAPKVVYELEHLGMPFDRNADGTIYQRPFGGHSANYGDKPVPRACAAADRTGHALLHTLYQSNVKMGTQFFVEWIALDLIRNEAGDVLGVTAIDQETGNIAVFQAKATLFATGGAGRVYRASTNAYINTGDGLGMAARAGIPLQDMEFWQFHPTGVAGAGVLLTEGCRGEGAILRNKDGEPFMERYAPTLKDLAPRDFVSRSMDQEIKEGRGCGPKGDYILLDMTHLGADTIMKRLPSVFEIGKKFANVDITKEPIPVVPTIHYQMGGIPTNMHGQVCLPEPGTDNYTKPVKGFYAIGECSCVSVHGANRLGTNSLLDLVVFGKAAGEHIIDYVTKHHGDEYAPLPTNVLEQTLARVRKLDESTSGENAQEVADAIRDIVQDHAGVFRTQALLDKGVKEILALEPRVRNIHLKDKSKVFNTARVEALEVENLYEVAKATLISAAARKECRGAHTVVDYELPADHPTYSYGRRDYEWMKHTLWYSSDNRLEYKPVRFKPLTVDPIPPAPRTF
Atome Classification :
(49 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130......-.-140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.-...-...320.......330.......340.......350.......360.......370....-...380......-.390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560......-----.570------....--....580.----..-.---...590.......---600-.........610
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MGAIN
P
K
E
D
YSNIQN
L
T
F
D
A
V
I
VGGGGSGM
R
A
S
Y
Q
L
A
QAG
L
K
V
A
V
L
T
K
VFPTRS
H
T
V
A
AQGGIGASLGNMQED
N
W
H
F
H
F
Y
D
TVKGSDWLG
D
Q
D
A
I
E
F
M
C
R
EA
P
K
V
V
Y
E
L
E
H
LGMPFDRNADG
T
I
YQRPFGGHSANYGD-K-PV
P
R
A
C
A
AADRT
G
H
A
L
L
H
T
L
Y
Q
S
N
V
K
M
G
T
Q
F
F
V
E
W
I
A
L
D
L
I
R
NEAG
D
V
L
G
V
T
A
IDQETG
N
I
A
V
F
Q
A
K
A
T
L
F
A
TGGAG
R
V
Y
R
AST
N
A
Y
I
NTGDGLG
M
A
ARAGIPLQDM
E
F
W
Q
FHPTGVAGAG
V
L
LTEGCRGE
G
A
I
L
RNKDG
E
P
F
M
E
R
Y
A
P
T
L
K
DL
A
P
R
D
F
V
S
R
S
M
D
Q
E
I
K
EGRGC-GPK-G
D
Y
I
L
L
D
M
T
HL
G
A
D
T
I
M
K
R
L
P
S
V
F
E
I
G
K
K
FANVDITKEPIPVV
P
T
I
H
Y
QMGGIPTNMHG
Q
-
V
CLPEPGTDNYT-KPV
K
G
F
Y
A
IG
E
C
S
C
V
S
VHGANRLG
T
N
S
L
L
D
L
V
V
FGKAA
G
E
H
I
I
D
Y
V
T
K
HHGDEYAPL
P
T
N
V
L
E
Q
T
L
A
R
V
R
K
LDESTSGE
N
A
Q
E
V
A
D
A
I
R
D
I
V
Q
D
H
A
G
V
F
R
T
Q
A
L
L
D
K
G
V
K
E
I
L
ALEPRV
R
N
I
H
LK
D
K
S
KVFNTA
R
V
E
A
L
E
V
E
N
L
Y
E
V
A
K
A
T
L
I
S
A
A
A
R
K
E
CRGA
H
T
V
V
D
Y
ELPADHPTYS-----YGR-------
R
D
Y
E
--
W
M
K
H
T
L
WY----SS-D---N
R
L
E
YKP
V
R
F
K
PL---T---VDPIPPAPRTF
102
HHSearch
97.92
51%
0
- C- -
-
2H88
2
SDHA_CHICK
A:
[12-621]
----------
Y
P
V
V
D
H
E
F
D
A
V
V
V
G
A
G
G
A
G
L
R
A
A
F
G
L
S
E
A
G
F
N
T
A
C
V
T
K
L
F
P
T
R
S
H
T
V
A
A
Q
G
G
I
N
A
A
L
G
N
M
E
D
D
N
W
R
W
H
F
Y
D
T
V
K
G
S
D
W
L
G
D
Q
D
A
I
H
Y
M
T
E
Q
A
P
A
A
V
I
E
L
E
N
Y
G
M
P
F
S
R
T
E
E
G
K
I
Y
Q
R
A
F
G
G
Q
S
L
Q
F
G
K
G
G
-
Q
A
H
R
C
C
C
V
A
D
R
T
G
H
S
L
L
H
T
L
Y
G
R
S
L
R
Y
D
T
S
Y
F
V
E
Y
F
A
L
D
L
L
M
E
-
N
G
E
C
R
G
V
I
A
L
C
I
E
D
G
T
I
H
R
F
R
A
K
N
T
V
I
A
T
G
G
Y
G
R
T
Y
F
S
C
T
S
A
H
T
S
T
G
D
G
T
A
M
V
T
R
A
G
L
P
C
Q
D
L
E
F
V
Q
F
H
P
T
G
I
Y
G
A
G
C
L
I
T
E
G
C
R
G
E
G
G
I
L
I
N
S
Q
G
E
R
F
M
E
R
Y
A
P
V
A
K
D
L
A
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
G
R
G
C
-
G
P
E
-
K
D
H
V
Y
L
Q
L
H
H
L
P
P
Q
Q
L
A
T
R
L
P
G
I
S
E
T
A
M
I
F
A
G
V
D
V
T
K
E
P
I
P
V
L
P
T
V
H
Y
N
M
G
G
I
P
T
N
Y
K
G
Q
-
V
I
T
H
---
V
N
G
E
D
-
K
V
V
P
G
L
Y
A
C
G
E
A
A
S
A
S
V
H
G
A
N
R
L
G
A
N
S
L
L
D
L
V
V
F
G
R
A
C
A
L
T
I
A
E
T
C
--
K
P
G
E
P
V
P
S
I
K
P
N
A
G
E
E
S
V
A
N
L
D
K
L
R
F
A
D
G
T
I
R
T
S
E
A
R
L
N
M
Q
K
T
M
Q
S
H
A
A
V
F
R
T
G
S
I
L
Q
E
G
C
E
K
L
S
Q
I
Y
R
D
L
A
H
L
K
T
F
D
R
G
I
V
W
N
T
D
L
V
E
T
L
E
L
Q
N
L
M
L
C
A
L
Q
T
I
Y
G
A
E
A
R
K
E
S
R
G
A
H
A
R
E
D
Y
K
L
R
I
D
E
F
D
Y
S
-----
K
P
L
QG
Q
Q
K
R
P
F
E
E
H
--
W
R
K
H
T
L
S
Y
----
V
D
V
K
SG
K
V
T
L
K
Y
R
P
V
I
D
R
T
L
NEE
D
---
C
S
S
V
P
P
A
I
R
S
Y
103
HHSearch
93.81
51%
-26
- C1 -
-
1YQ3
6
SDHA_CHICK
A:
[12-621]
----------
Y
P
V
V
D
H
E
F
D
A
V
V
V
G
A
G
G
A
G
L
R
A
A
F
G
L
S
E
A
G
F
N
T
A
C
V
T
K
L
F
P
T
R
S
H
T
V
A
A
Q
G
G
I
N
A
A
L
G
N
M
E
D
D
N
W
R
W
H
F
Y
D
T
V
K
G
S
D
W
L
G
D
Q
D
A
I
H
Y
M
T
E
Q
A
P
A
A
V
I
E
L
E
N
Y
G
M
P
F
S
R
T
E
E
G
K
I
Y
Q
R
A
F
G
G
Q
S
L
Q
F
G
K
G
G
-
Q
A
H
R
C
C
C
V
A
D
R
T
G
H
S
L
L
H
T
L
Y
G
R
S
L
R
Y
D
T
S
Y
F
V
E
Y
F
A
L
D
L
L
M
E
-
N
G
E
C
R
G
V
I
A
L
C
I
E
D
G
T
I
H
R
F
R
A
K
N
T
V
I
A
T
G
G
Y
G
R
T
Y
F
S
C
T
S
A
H
T
S
T
G
D
G
T
A
M
V
T
R
A
G
L
P
C
Q
D
L
E
F
V
Q
F
H
P
T
G
I
Y
G
A
G
C
L
I
T
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G
C
R
G
E
G
G
I
L
I
N
S
Q
G
E
R
F
M
E
R
Y
A
P
V
A
K
D
L
A
S
R
D
V
V
S
R
S
M
T
I
E
I
R
E
G
R
G
C
-
G
P
E
-
K
D
H
V
Y
L
Q
L
H
H
L
P
P
Q
Q
L
A
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R
L
P
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I
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A
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V
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P
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P
T
V
H
Y
N
M
G
G
I
P
T
N
Y
K
G
Q
-
V
I
T
H
---
V
N
G
E
D
-
K
V
V
P
G
L
Y
A
C
G
E
A
A
S
A
S
V
H
G
A
N
R
L
G
A
N
S
L
L
D
L
V
V
F
G
R
A
C
A
L
T
I
A
E
T
C
--
K
P
G
E
P
V
P
S
I
K
P
N
A
G
E
E
S
V
A
N
L
D
K
L
R
F
A
D
G
T
I
R
T
S
E
A
R
L
N
M
Q
K
T
M
Q
S
H
A
A
V
F
R
T
G
S
I
L
Q
E
G
C
E
K
L
S
Q
I
Y
R
D
L
A
H
L
K
T
F
D
R
G
I
V
W
N
T
D
L
V
E
T
L
E
L
Q
N
L
M
L
C
A
L
Q
T
I
Y
G
A
E
A
R
K
E
S
R
G
A
H
A
R
E
D
Y
K
L
R
I
D
E
F
D
Y
S
-----
K
P
L
QGQQKRP
F
E
E
H
--
W
R
K
H
T
L
S
Y
----
V
D
V
K
SG
K
V
T
L
K
Y
R
P
V
I
D
R
T
L
NEE
D
---
C
S
S
V
P
P
A
I
R
S
Y
29
PsiBlast_CBE
93.56
52%
-26
- C1 -
-
2WDV
7
SDHA_ECOLI
I:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
S
R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
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Q
A
A
R
T
A
A
A
A
D
R
T
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H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
V
G
M
A
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R
A
G
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P
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M
E
M
W
Q
F
H
P
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I
A
G
A
G
V
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T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
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H
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G
K
E
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A
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I
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P
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M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
10
PsiBlast_PDB
93.25
52%
-24
- C1 -
-
2WU5
2
SDHA_ECOLI
A:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
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H
M
G
L
P
F
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R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
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N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
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N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
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G
M
A
I
R
A
G
V
P
V
Q
D
M
E
M
W
Q
F
H
P
T
G
I
A
G
A
G
V
L
V
T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
D
H
L
G
K
E
V
L
E
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R
L
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L
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T
F
A
H
V
D
P
V
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E
P
I
P
V
I
P
T
C
H
Y
M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
5
PsiBlast_PDB
93.01
52%
-27
- C1 -
-
2WDV
2
SDHA_ECOLI
A:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
S
R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
V
G
M
A
I
R
A
G
V
P
V
Q
D
M
E
M
W
Q
F
H
P
T
G
I
A
G
A
G
V
L
V
T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
D
H
L
G
K
E
V
L
E
S
R
L
P
G
I
L
E
L
S
R
T
F
A
H
V
D
P
V
K
E
P
I
P
V
I
P
T
C
H
Y
M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
26
PsiBlast_CBE
92.96
52%
-25
- C1 -
-
2WS3
2
SDHA_ECOLI
E:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
S
R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
V
G
M
A
I
R
A
G
V
P
V
Q
D
M
E
M
W
Q
F
H
P
T
G
I
A
G
A
G
V
L
V
T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
D
H
L
G
K
E
V
L
E
S
R
L
P
G
I
L
E
L
S
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T
F
A
H
V
D
P
V
K
E
P
I
P
V
I
P
T
C
H
Y
M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
33
PsiBlast_CBE
92.91
52%
-24
- C1 -
-
2WDQ
13
SDHA_ECOLI
I:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
S
R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
V
G
M
A
I
R
A
G
V
P
V
Q
D
M
E
M
W
Q
F
H
P
T
G
I
A
G
A
G
V
L
V
T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
D
H
L
G
K
E
V
L
E
S
R
L
P
G
I
L
E
L
S
R
T
F
A
H
V
D
P
V
K
E
P
I
P
V
I
P
T
C
H
Y
M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
21
PsiBlast_CBE
92.86
52%
-24
- C1 -
-
2WU5
10
SDHA_ECOLI
I:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
G
D
Q
D
A
I
E
Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
S
R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
E
W
Y
A
L
D
L
V
K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
E
V
V
Y
F
K
A
R
A
T
V
L
A
T
G
G
A
G
R
I
Y
Q
S
T
T
N
A
H
I
N
T
G
D
G
V
G
M
A
I
R
A
G
V
P
V
Q
D
M
E
M
W
Q
F
H
P
T
G
I
A
G
A
G
V
L
V
T
E
G
C
R
G
E
G
G
Y
L
L
N
K
H
G
E
R
F
M
E
R
Y
A
P
N
A
K
D
L
A
G
R
D
V
V
A
R
S
I
M
I
E
I
R
E
G
R
G
C
D
G
P
W
-
G
P
H
A
K
L
K
L
D
H
L
G
K
E
V
L
E
S
R
L
P
G
I
L
E
L
S
R
T
F
A
H
V
D
P
V
K
E
P
I
P
V
I
P
T
C
H
Y
M
M
G
G
I
P
T
K
V
T
G
Q
A
L
T
V
N
E
K
G
E
D
V
V
----
V
P
G
L
F
A
V
G
E
I
A
C
V
S
V
H
G
A
N
R
L
G
G
N
S
L
L
D
L
V
V
F
G
R
A
A
G
L
H
L
Q
E
S
I
A
E
Q
G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
M
A
K
G
L
E
Q
L
K
V
I
R
E
R
L
K
N
A
R
L
D
D
T
S
S
E
F
N
T
Q
R
V
E
C
L
E
L
D
N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
22
PsiBlast_CBE
92.78
52%
-24
- C1 -
-
2WU5
2
SDHA_ECOLI
E:
[8-588]
-----------------
F
D
A
V
V
I
G
A
G
G
A
G
M
R
A
A
L
Q
I
S
Q
S
G
Q
T
C
A
L
L
S
K
V
F
P
T
R
S
H
T
V
S
A
Q
G
G
I
T
V
A
L
G
N
T
H
E
D
N
W
E
W
H
M
Y
D
T
V
K
G
S
D
Y
I
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D
Q
D
A
I
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Y
M
C
K
T
G
P
E
A
I
L
E
L
E
H
M
G
L
P
F
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R
L
D
D
G
R
I
Y
Q
R
P
F
G
G
Q
S
K
N
F
G
G
-
E
-
Q
A
A
R
T
A
A
A
A
D
R
T
G
H
A
L
L
H
T
L
Y
Q
Q
N
L
K
N
H
T
T
I
F
S
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W
Y
A
L
D
L
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K
N
Q
D
G
A
V
V
G
C
T
A
L
C
I
E
T
G
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V
Y
F
K
A
R
A
T
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L
A
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G
A
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C
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G
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Y
L
L
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H
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F
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E
R
Y
A
P
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A
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D
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A
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R
D
V
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A
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S
I
M
I
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I
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E
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R
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C
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W
-
G
P
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A
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L
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M
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V
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V
N
E
K
G
E
D
V
V
----
V
P
G
L
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A
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A
C
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S
V
H
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A
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R
L
G
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N
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L
L
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L
V
V
F
G
R
A
A
G
L
H
L
Q
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I
A
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G
A
L
R
D
A
--
S
E
S
D
V
E
A
S
L
D
R
L
N
R
W
N
N
N
R
N
G
E
D
P
V
A
I
R
K
A
L
Q
E
C
M
Q
H
N
F
S
V
F
R
E
G
D
A
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A
K
G
L
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Q
L
K
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R
L
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N
A
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L
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S
E
F
N
T
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R
V
E
C
L
E
L
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N
L
M
E
T
A
Y
A
T
A
V
S
A
N
F
R
T
E
S
R
G
A
H
S
R
F
D
F
P
---------------
D
R
-------
D
D
E
N
--
W
L
C
H
S
L
Y
L
----
P
E
-
S
---
E
S
M
T
R
R
S
V
N
M
E
P
K
---
L
---
R
P
A
F
P
P
K
I
R
T
Y
54
PsiBlast_CBE
92.62
50%
0
- C- -
-
2FBW
2
SDHA_CHICK
A:
[37-621]
-----------------------------------
L
S
E
A
G
F
N
T
A
C
V
T
K
L
F
P
T
R
S
H
T
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A
A
Q
G
G
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N
A
A
L
G
N
M
E
D
D
N
W
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W
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F
Y
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V
K
G
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D
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Q
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A
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E
N
Y
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M
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T
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K
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A
F
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-
G
G
Q
A
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C
C
C
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-
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N
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-
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----
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V
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A
C
G
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A
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L
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--
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KPLQG
Q
Q
K
-------
R
P
F
E
EH
W
R
K
H
T
L
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Y
V
DVK
S
G
-
K
---
V
T
L
K
Y
R
P
V
I
D
R
T
L
---
N
EED
C
S
S
V
P
P
A
I
R
S
Y
53
PsiBlast_CBE
92.62
50%
0
- C- -
-
2FBW
1
SDHA_CHICK
N:
[37-621]
-----------------------------------
L
S
E
A
G
F
N
T
A
C
V
T
K
L
F
P
T
R
S
H
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A
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G
G
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N
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A
L
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N
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S
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---
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P
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---
N
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C
S
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V
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S
Y