@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSK8: (2017-12-08 )
MATEIKAPVFPESVADGTIATWHKKVGEPASRDEVICDIETDKVVLEVVAPADGSLVAIIKGEGDTVLSDEVIAQFEAGAGAAAAAPAAVEQAVAQTQAGAAPVVERNETVSDQAPAVRKALTESGIAASDVQGTGRGGRITKEDVANHQAKPAANVTPLSVAVGERIEKRVPMTRLRKRVAERLLAATQETAMLTTFNEVNMKPIMELRKQYKDAFEKRHGARLGFMSFFVKAATEALKRYPAVNASIDGDDIVYHGYYDIGVAVSSDRGLVVPVLRDTDRMSYAEVEAGIAAYAAKARDGKLSIEEMTGGTFTITNGGTFGSLLSTPILNQPQTGILGMHKIQERPMAVNGQVEILPMMYLALSYDHRMIDGKEAVGFLVAIKELLEEPAKLILDL
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......--250-.--.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350...--.....360.......370.......380.......390......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MATEIKAPVFPESVADG
T
I
A
T
W
H
K
KVGEPASRD
E
V
I
C
DIET
D
K
V
V
L
E
V
VAPAD
G
S
L
V
A
I
I
KGEGDTVL
S
D
E
V
I
A
Q
FEAGAGAAAA
A
P
A
A
V
E
Q
A
V
A
Q
TQAGAAPVVERNETVSDQ
A
P
A
V
R
K
A
L
T
ESGIAASDVQGTGRGGRI
T
K
E
D
V
ANHQAKPAANV
T
P
L
S
V
A
V
G
E
R
I
E
KRV
P
M
T
R
L
R
K
R
V
A
E
R
L
L
A
A
T
QE
T
A
M
L
T
TFNEV
N
M
K
P
I
M
E
L
R
K
Q
Y
K
D
A
F
E
K
RHGAR
L
G
F
M
S
F
F
V
K
A
A
T
E
A
L
K
RYPAVNASI--DG--D--
D
I
V
Y
H
G
Y
Y
D
I
G
V
A
VSSDR
G
L
V
V
P
VLRDTDR
M
S
Y
A
E
V
E
A
G
I
A
A
Y
AAKARDG
K
L
S
I
E
EMTG
G
T
F
T
ITNGGT
F
G
S
L
LSTPILNQPQTG
I
L
G
M
H
K
IQERPMAV-NG
Q
--
V
E
I
L
P
M
M
Y
L
A
LSYDHRMID
G
K
E
A
V
G
F
L
V
A
I
K
E
L
L
E
E
P
A
K
L
ILDL
3
PsiBlast_PDB
90.54
74%
-119
- C2 -
-
1E2O
-
ODO2_ECOLI
A:
[2-233]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
E
K
R
V
P
M
T
R
L
R
K
R
V
A
E
R
L
L
E
A
K
N
S
T
A
M
L
T
T
F
N
E
V
N
M
K
P
I
M
D
L
R
K
Q
Y
G
E
A
F
E
K
R
H
G
I
R
L
G
F
M
S
F
Y
V
K
A
V
V
E
A
L
K
R
Y
P
E
V
N
A
S
I
--
D
G
--
D
--
D
V
V
Y
H
N
Y
F
D
V
S
M
A
V
S
T
--
G
L
V
T
P
V
L
R
D
V
D
T
L
G
M
A
D
I
E
K
K
I
K
E
L
A
V
K
G
-
D
G
K
L
T
V
E
D
L
T
G
G
N
F
T
I
T
N
G
G
V
F
G
S
L
M
S
T
P
I
I
N
P
P
Q
S
A
I
L
G
M
H
A
I
K
D
R
P
M
A
V
-
N
G
Q
--
V
E
I
L
P
M
M
Y
L
A
L
S
Y
D
H
R
L
I
D
G
R
E
S
V
G
F
L
V
T
I
K
E
L
L
E
D
P
T
R
L
L
L
D
V
1
PsiBlast_PDB
88.90
74%
-118
- C2 -
-
1C4T
-
ODO2_ECOLI
A:
[2-230]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
E
K
R
V
P
M
---
R
K
R
V
A
E
R
L
L
E
A
K
N
S
T
A
M
L
T
T
F
N
E
V
N
M
K
P
I
M
D
L
R
K
Q
Y
G
E
A
F
E
K
R
H
G
I
R
L
G
F
M
S
F
Y
V
K
A
V
V
E
A
L
K
R
Y
P
E
V
N
A
S
I
--
D
G
--
D
--
D
V
V
Y
H
N
Y
F
D
V
S
M
A
V
S
T
P
R
G
L
V
T
P
V
L
R
D
V
D
T
L
G
M
A
D
I
E
K
K
I
K
E
L
A
V
K
G
R
D
G
K
L
T
V
E
D
L
T
G
G
N
F
T
I
T
N
G
G
V
F
G
S
L
M
S
T
P
I
I
N
P
P
Q
S
A
I
L
G
M
H
A
I
K
D
R
P
M
A
V
-
N
G
Q
--
V
E
I
L
P
M
M
Y
L
A
L
S
Y
D
H
R
L
I
D
G
R
E
S
V
G
F
L
V
T
I
K
E
L
L
E
D
P
T
R
L
L
---
71
HHSearch
88.75
75%
-110
- C2 -
-
1SCZ
-
ODO2_ECOLI
A:
[174-403]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
K
R
V
P
M
T
R
L
R
K
R
V
A
E
R
L
L
E
A
K
N
S
T
A
M
L
T
T
F
N
E
V
N
M
K
P
I
M
D
L
R
K
Q
Y
G
E
A
F
E
K
R
H
G
I
R
L
G
F
M
S
F
Y
V
K
A
V
V
E
A
L
K
R
Y
P
E
V
N
A
S
I
--
D
G
--
D
--
D
V
V
Y
H
N
Y
F
D
V
S
M
A
V
S
T
P
R
G
L
V
T
P
V
L
R
D
V
D
T
L
G
M
A
D
I
E
K
K
I
K
E
L
A
V
K
G
R
D
G
K
L
T
V
E
D
L
T
G
G
N
F
T
I
T
N
G
G
V
F
G
S
L
M
S
T
P
I
I
N
P
P
Q
S
A
I
L
G
M
H
A
I
K
D
R
P
M
A
V
-
N
G
Q
--
V
E
I
L
P
M
M
Y
L
A
L
S
Y
D
H
R
L
I
D
G
R
E
S
V
G
F
L
V
T
I
K
E
L
L
E
D
P
T
R
L
L
L
D
-
2
PsiBlast_PDB
88.71
74%
-109
- C2 -
-
1SCZ
-
ODO2_ECOLI
A:
[173-404]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
E
K
R
V
P
M
T
R
L
R
K
R
V
A
E
R
L
L
E
A
K
N
S
T
A
M
L
T
T
F
N
E
V
N
M
K
P
I
M
D
L
R
K
Q
Y
G
E
A
F
E
K
R
H
G
I
R
L
G
F
M
S
F
Y
V
K
A
V
V
E
A
L
K
R
Y
P
E
V
N
A
S
I
--
D
G
--
D
--
D
V
V
Y
H
N
Y
F
D
V
S
M
A
V
S
T
P
R
G
L
V
T
P
V
L
R
D
V
D
T
L
G
M
A
D
I
E
K
K
I
K
E
L
A
V
K
G
R
D
G
K
L
T
V
E
D
L
T
G
G
N
F
T
I
T
N
G
G
V
F
G
S
L
M
S
T
P
I
I
N
P
P
Q
S
A
I
L
G
M
H
A
I
K
D
R
P
M
A
V
-
N
G
Q
--
V
E
I
L
P
M
M
Y
L
A
L
S
Y
D
H
R
L
I
D
G
R
E
S
V
G
F
L
V
T
I
K
E
L
L
E
D
P
T
R
L
L
L
D
V
81
HHSearch
75.98
36%
-127
- C2 -
-
3MAE
4
?
B:
[14-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
A
G
D
K
E
I
P
I
N
G
V
R
K
A
I
A
K
H
M
S
V
S
K
Q
E
I
P
H
A
W
M
M
V
E
V
D
A
T
G
L
V
R
Y
R
N
A
V
K
D
S
F
K
K
E
E
G
Y
S
L
T
Y
F
A
F
F
I
K
A
V
A
Q
A
L
K
E
F
P
Q
L
N
S
T
W
--
A
G
--
D
--
K
I
I
E
H
A
N
I
N
I
S
I
A
I
A
A
G
D
L
L
Y
V
P
V
I
K
N
A
D
E
K
S
I
K
G
I
A
R
E
I
S
E
L
A
G
K
A
R
N
G
K
L
S
Q
A
D
M
E
G
G
T
F
T
V
N
S
T
G
S
F
G
S
V
Q
S
M
G
I
I
N
H
P
Q
A
A
I
L
Q
V
E
S
I
V
K
R
P
V
I
I
-
D
D
M
--
I
A
V
R
D
M
V
N
L
C
L
S
I
D
H
R
I
L
D
G
L
L
A
G
K
F
L
Q
A
I
K
A
N
V
E
K
I
S
K
E
N
T
A
-
80
HHSearch
75.88
36%
-128
- C2 -
-
3MAE
4
?
C:
[14-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
A
G
D
K
E
I
P
I
N
G
V
R
K
A
I
A
K
H
M
S
V
S
K
Q
E
I
P
H
A
W
M
M
V
E
V
D
A
T
G
L
V
R
Y
R
N
A
V
K
D
S
F
K
K
E
E
G
Y
S
L
T
Y
F
A
F
F
I
K
A
V
A
Q
A
L
K
E
F
P
Q
L
N
S
T
W
--
A
G
--
D
--
K
I
I
E
H
A
N
I
N
I
S
I
A
I
A
A
G
D
L
L
Y
V
P
V
I
K
N
A
D
E
K
S
I
K
G
I
A
R
E
I
S
E
L
A
G
K
A
R
N
G
K
L
S
Q
A
D
M
E
G
G
T
F
T
V
N
S
T
G
S
F
G
S
V
Q
S
M
G
I
I
N
H
P
Q
A
A
I
L
Q
V
E
S
I
V
K
R
P
V
I
I
-
D
D
M
--
I
A
V
R
D
M
V
N
L
C
L
S
I
D
H
R
I
L
D
G
L
L
A
G
K
F
L
Q
A
I
K
A
N
V
E
K
I
S
K
E
N
T
A
-
23
PsiBlast_CBE
75.81
36%
-128
- C2 -
-
3MAE
4
?
B:
[9-242]
------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
P
V
R
S
A
A
G
D
---
K
E
I
P
I
N
G
V
R
K
A
I
A
K
H
M
S
V
S
K
Q
E
I
P
H
A
W
M
M
V
E
V
D
A
T
G
L
V
R
Y
R
N
A
V
K
D
S
F
K
K
E
E
G
Y
S
L
T
Y
F
A
F
F
I
K
A
V
A
Q
A
L
K
E
F
P
Q
L
N
S
T
W
--
A
G
--
D
--
K
I
I
E
H
A
N
I
N
I
S
I
A
I
A
A
G
D
L
L
Y
V
P
V
I
K
N
A
D
E
K
S
I
K
G
I
A
R
E
I
S
E
L
A
G
K
A
R
N
G
K
L
S
Q
A
D
M
E
G
G
T
F
T
V
N
S
T
G
S
F
G
S
V
Q
S
M
G
I
I
N
H
P
Q
A
A
I
L
Q
V
E
S
I
V
K
R
P
V
I
I
-
D
D
M
--
I
A
V
R
D
M
V
N
L
C
L
S
I
D
H
R
I
L
D
G
L
L
A
G
K
F
L
Q
A
I
K
A
N
V
E
K
I
S
K
-----
22
PsiBlast_CBE
75.60
36%
-128
- C2 -
-
3MAE
4
?
C:
[10-242]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
V
R
S
A
A
G
D
---
K
E
I
P
I
N
G
V
R
K
A
I
A
K
H
M
S
V
S
K
Q
E
I
P
H
A
W
M
M
V
E
V
D
A
T
G
L
V
R
Y
R
N
A
V
K
D
S
F
K
K
E
E
G
Y
S
L
T
Y
F
A
F
F
I
K
A
V
A
Q
A
L
K
E
F
P
Q
L
N
S
T
W
--
A
G
--
D
--
K
I
I
E
H
A
N
I
N
I
S
I
A
I
A
A
G
D
L
L
Y
V
P
V
I
K
N
A
D
E
K
S
I
K
G
I
A
R
E
I
S
E
L
A
G
K
A
R
N
G
K
L
S
Q
A
D
M
E
G
G
T
F
T
V
N
S
T
G
S
F
G
S
V
Q
S
M
G
I
I
N
H
P
Q
A
A
I
L
Q
V
E
S
I
V
K
R
P
V
I
I
-
D
D
M
--
I
A
V
R
D
M
V
N
L
C
L
S
I
D
H
R
I
L
D
G
L
L
A
G
K
F
L
Q
A
I
K
A
N
V
E
K
I
S
K
-----
7
PsiBlast_PDB
75.48
36%
-126
- C2 -
-
3MAE
5
?
A:
[15-242]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
G
D
---
K
E
I
P
I
N
G
V
R
K
A
I
A
K
H
M
S
V
S
K
Q
E
I
P
H
A
W
M
M
V
E
V
D
A
T
G
L
V
R
Y
R
N
A
V
K
D
S
F
K
K
E
E
G
Y
S
L
T
Y
F
A
F
F
I
K
A
V
A
Q
A
L
K
E
F
P
Q
L
N
S
T
W
--
A
G
--
D
--
K
I
I
E
H
A
N
I
N
I
S
I
A
I
A
A
G
D
L
L
Y
V
P
V
I
K
N
A
D
E
K
S
I
K
G
I
A
R
E
I
S
E
L
A
G
K
A
R
N
G
K
L
S
Q
A
D
M
E
G
G
T
F
T
V
N
S
T
G
S
F
G
S
V
Q
S
M
G
I
I
N
H
P
Q
A
A
I
L
Q
V
E
S
I
V
K
R
P
V
I
I
-
D
D
M
--
I
A
V
R
D
M
V
N
L
C
L
S
I
D
H
R
I
L
D
G
L
L
A
G
K
F
L
Q
A
I
K
A
N
V
E
K
I
S
K
-----
72
HHSearch
69.77
32%
-37
- C2 -
-
1DPD
-
ODP2_AZOVI
A:
[405-637]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Y
G
E
I
E
E
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
A
V
A
E
-
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
--
A
P
SG
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
A
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
17
PsiBlast_PDB
69.06
33%
-38
- C2 -
-
1DPC
-
ODP2_AZOVI
A:
[398-637]
------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
V
D
F
A
K
Y
G
E
I
E
E
-
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
A
V
A
E
K
A
-
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
A
P
S
G
--
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
D
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
18
PsiBlast_PDB
68.69
33%
-36
- C2 -
-
1EAA
-
ODP2_AZOVI
A:
[398-637]
------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
V
D
F
A
K
Y
G
E
I
E
E
-
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
-
A
V
A
K
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
A
P
S
G
--
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
74
HHSearch
68.42
30%
-44
- C2 -
-
2II3
-
ODB2_BOVIN
B:
[29-261]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
D
R
T
E
P
V
K
G
F
H
K
A
M
V
K
T
M
S
A
A
-
L
K
I
P
H
F
G
Y
C
D
E
V
D
L
T
E
L
V
K
L
R
E
E
L
K
P
I
A
F
-
A
R
G
I
K
L
S
F
M
P
F
F
L
K
A
A
S
L
G
L
L
Q
F
P
I
L
N
A
S
V
--
D
E
NC
Q
--
N
I
T
Y
K
A
S
H
N
I
G
I
A
M
D
T
E
Q
G
L
I
V
P
N
V
K
N
V
Q
I
R
S
I
F
E
I
A
T
E
L
N
R
L
Q
K
L
G
S
A
G
Q
L
S
T
N
D
L
I
G
G
T
F
T
L
S
N
I
G
S
I
G
G
T
Y
A
K
P
V
I
L
P
P
E
V
A
I
G
A
L
G
T
I
K
A
L
P
R
F
N
E
K
G
E
--
V
C
K
A
Q
I
M
N
V
S
W
S
A
D
H
R
I
I
D
G
A
T
V
S
R
F
S
N
L
W
K
S
Y
L
E
N
P
A
F
M
L
L
D
L
75
HHSearch
68.25
32%
-37
- C2 -
-
1DPB
-
ODP2_AZOVI
A:
[406-637]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
E
I
E
E
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
A
V
A
-
E
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
--
A
P
SG
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
C
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
53
PsiBlast_CBE
68.01
33%
-37
- C2 -
-
1EAE
1
A:
[4-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
V
D
F
A
K
Y
G
E
I
E
E
-
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
-
A
V
A
K
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
A
P
S
G
--
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
78
HHSearch
67.89
39%
-32
- C2 -
-
1B5S
-
ODP2_GEOSE
C:
[194-425]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
P
E
T
R
E
K
M
S
G
I
R
R
A
I
A
K
A
M
V
H
S
K
H
T
A
P
H
V
T
L
M
D
E
A
D
V
T
K
L
V
A
H
R
K
K
F
K
A
I
A
A
-
E
K
G
I
K
L
T
F
L
P
Y
V
V
K
A
L
V
S
A
L
R
E
Y
P
V
L
N
T
S
I
--
D
D
ET
E
--
E
I
I
Q
K
H
Y
Y
N
I
G
I
A
A
D
T
D
R
G
L
L
V
P
V
I
K
H
A
D
R
K
P
I
F
A
L
A
Q
E
I
N
E
L
A
E
K
A
R
D
G
K
L
T
P
G
E
M
K
G
A
S
C
T
I
T
N
I
G
S
A
G
G
Q
W
F
T
P
V
I
N
H
P
E
V
A
I
L
G
I
G
R
I
A
E
K
P
I
V
R
-
D
G
E
--
I
V
A
A
P
M
L
A
L
S
L
S
F
D
H
R
M
I
D
G
A
T
A
Q
K
A
L
N
H
I
K
R
L
L
S
D
P
E
L
L
L
M
--
6
PsiBlast_PDB
67.64
38%
-30
- C2 -
-
1B5S
-
ODP2_GEOSE
A:
[193-425]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
F
P
E
T
R
E
K
M
S
G
I
R
R
A
I
A
K
A
M
V
H
S
K
H
T
A
P
H
V
T
L
M
D
E
A
D
V
T
K
L
V
A
H
R
K
K
F
K
-
A
I
A
A
E
K
G
I
K
L
T
F
L
P
Y
V
V
K
A
L
V
S
A
L
R
E
Y
P
V
L
N
T
S
I
--
D
D
--
E
TE
E
I
I
Q
K
H
Y
Y
N
I
G
I
A
A
D
T
D
R
G
L
L
V
P
V
I
K
H
A
D
R
K
P
I
F
A
L
A
Q
E
I
N
E
L
A
E
K
A
R
D
G
K
L
T
P
G
E
M
K
G
A
S
C
T
I
T
N
I
G
S
A
G
G
Q
W
F
T
P
V
I
N
H
P
E
V
A
I
L
G
I
G
R
I
A
E
K
P
I
V
R
-
D
G
E
--
I
V
A
A
P
M
L
A
L
S
L
S
F
D
H
R
M
I
D
G
A
T
A
Q
K
A
L
N
H
I
K
R
L
L
S
D
P
E
L
L
L
M
--
54
PsiBlast_CBE
67.28
33%
-33
- C2 -
-
1EAD
1
A:
[4-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
V
D
F
A
K
Y
G
E
I
E
E
-
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
-
A
V
A
K
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
A
P
S
G
--
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--
11
PsiBlast_PDB
65.49
29%
-80
- C2 -
-
3B8K
-
ODP2_HUMAN
A:
[337-561]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
I
S
N
I
R
R
V
I
A
Q
R
L
M
Q
S
K
Q
T
I
P
H
Y
Y
L
S
I
D
V
N
M
G
E
V
L
L
V
R
K
E
L
N
K
I
L
E
G
R
--
S
K
I
S
V
N
D
F
I
I
K
A
S
A
L
A
C
L
K
V
P
E
A
N
S
S
W
--
M
D
--
T
--
V
I
R
Q
N
H
V
V
D
V
S
V
A
V
S
T
P
A
G
L
I
T
P
I
V
F
N
A
H
I
K
G
V
E
T
I
A
N
D
V
V
S
L
A
T
K
A
R
E
G
K
L
Q
P
H
E
F
Q
G
G
T
F
T
I
S
N
L
G
M
F
G
I
K
N
F
S
A
I
I
N
P
P
Q
A
C
I
L
A
I
G
A
S
E
D
K
L
V
P
A
-
D
N
E
KG
F
D
V
A
S
M
M
S
V
T
L
S
C
D
H
R
V
V
D
G
A
V
G
A
Q
W
L
A
E
F
R
K
Y
L
E
K
P
I
T
M
L
L
--
20
PsiBlast_PDB
65.35
33%
0
- C- -
-
1EAC
1
A:
[4-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------
I
P
P
V
D
F
A
K
Y
G
E
I
E
E
-
V
P
M
T
R
L
M
Q
I
G
A
T
N
L
H
R
S
W
L
N
V
P
H
V
T
Q
F
E
S
A
D
I
T
E
L
E
A
F
R
V
A
Q
K
-
A
V
A
K
K
A
G
V
K
L
T
V
L
P
L
L
L
K
A
C
A
Y
L
L
K
E
L
P
D
F
N
S
S
L
A
P
S
G
--
Q
--
A
L
I
R
K
K
Y
V
H
I
G
F
A
V
D
T
P
D
G
L
L
V
P
V
I
R
N
V
D
Q
K
S
L
L
Q
L
A
A
E
A
A
E
L
A
E
K
A
R
S
K
K
L
G
A
D
A
M
Q
G
A
C
F
T
I
S
S
L
G
H
I
G
G
T
A
F
T
P
I
V
N
A
P
E
V
A
I
L
G
V
S
K
A
S
M
Q
P
V
W
D
-
G
K
A
--
F
Q
P
R
L
M
L
P
L
S
L
S
Y
D
H
R
V
I
N
G
A
A
A
A
R
F
T
K
R
L
G
D
L
L
A
D
I
R
A
I
L
L
--