@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSL1: (2017-12-09 )
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEAVRETNADASVIYVPAPFVLDSIVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVTAPKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA
Atome Classification :
(23 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.....----..230.......240.......250.......260.......270.......280.......290....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
S
V
L
INKD
T
K
V
L
V
Q
GFTGKNGTFHS
A
Q
ALDYGT
K
V
VGGVTPGKGG
T
T
H
LD
L
P
V
F
N
T
M
K
E
A
V
R
ETNADA
S
V
I
Y
VP
A
P
F
V
L
D
S
I
V
E
A
V
DSGV
G
L
I
V
V
ITEGVP
T
I
D
M
L
K
A
K
R
Y
L
ETNGNG
T
R
LVGPNCPGVITPG
E
C
K
I
GIMPGHIHQPG
R
I
G
I
I
SRSG
T
L
T
Y
E
A
V
A
Q
T
T
KLGLGQS
T
C
IGIGGDPIPG
M
N
Q
I
E
A
L
Q
L
FQDDPDT
D
A
I
I
M
I
GEIGGT
A
E
E
E
A
A
E
F
I
K
S
N----VTK
P
V
V
G
Y
IAGVTAPKGKRMGHA
G
A
I
I
SGGQG
T
A
E
E
K
F
A
A
F
E
K
AGMAYTR
S
P
A
E
L
G
S
T
M
L
Q
V
L
K
EKGLA
23
PsiBlast_CBE
96.13
71%
0
- C- -
-
1JKJ
1
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
1
PsiBlast_PDB
96.13
71%
0
- C- -
-
1JKJ
4
SUCD_ECOLI
A:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
5
PsiBlast_PDB
92.90
70%
-101
- C3 -
-
2NU7
2
SUCD_ECOLI
A:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
S
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
28
PsiBlast_CBE
92.64
70%
-107
- C3 -
-
2NUA
1
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
V
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
26
PsiBlast_CBE
92.58
70%
-100
- C3 -
-
2NU7
2
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
S
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
6
PsiBlast_PDB
92.43
70%
-101
- C3 -
-
2NU8
2
SUCD_ECOLI
A:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
T
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
22
PsiBlast_CBE
92.36
71%
-100
- C3 -
-
1JLL
1
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
34
HHSearch
92.25
71%
-99
- C3 -
-
2NU8
1
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
--
E
A
G
V
R
M
I
G
P
N
T
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
7
PsiBlast_PDB
92.10
70%
-107
- C3 -
-
2NUA
1
SUCD_ECOLI
A:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
V
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
2
PsiBlast_PDB
91.70
71%
-102
- C3 -
-
1JLL
1
SUCD_ECOLI
A:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
27
PsiBlast_CBE
91.61
70%
-99
- C3 -
-
2NU8
1
SUCD_ECOLI
D:
[1-287]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
T
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
------
35
HHSearch
91.56
71%
-101
- C3 -
-
1CQJ
1
SUCD_ECOLI
A:
[1-286]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
--
E
A
G
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
-------
24
PsiBlast_CBE
91.37
70%
-101
- C3 -
-
1CQJ
1
SUCD_ECOLI
D:
[1-286]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
-------
4
PsiBlast_PDB
90.92
70%
-101
- C3 -
-
1CQJ
1
SUCD_ECOLI
A:
[1-286]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
-------
11
PsiBlast_PDB
90.77
61%
-81
- C3 -
-
2FPG
-
SUCA_PIG
A:
[9-304]
--
L
Y
V
D
K
N
T
K
V
I
C
Q
G
F
T
G
K
Q
G
T
F
H
S
Q
Q
A
L
E
Y
G
T
N
L
V
G
G
T
T
P
G
K
G
G
K
T
H
L
G
L
P
V
F
N
T
V
K
E
A
K
E
Q
T
G
A
T
A
S
V
I
Y
V
P
P
P
F
A
A
A
A
I
N
E
A
I
D
A
E
V
P
L
V
V
C
I
T
E
G
I
P
Q
Q
D
M
V
R
V
K
H
R
L
L
R
Q
G
K
-
T
R
L
I
G
P
N
C
P
G
V
I
N
P
G
E
C
K
I
G
I
M
P
G
H
I
H
K
K
G
R
I
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
H
Q
T
T
Q
V
G
L
G
Q
S
L
C
V
G
I
G
G
D
P
F
N
G
T
D
F
T
D
C
L
E
I
F
L
N
D
P
A
T
E
G
I
I
L
I
G
E
I
G
G
N
A
E
E
N
A
A
E
F
L
K
Q
H
NSGP
K
S
K
P
V
V
S
F
I
A
G
L
T
A
P
P
G
R
R
M
G
H
A
G
A
I
I
A
G
G
K
G
G
A
K
E
K
I
T
A
L
Q
S
A
G
V
V
V
S
M
S
P
A
Q
L
G
T
T
I
Y
K
E
F
E
K
R
K
M
-
21
PsiBlast_CBE
90.68
71%
-103
- C3 -
-
1SCU
2
SUCD_ECOLI
D:
[1-288]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
L
K
-----
8
PsiBlast_PDB
90.38
61%
-84
- C3 -
-
1EUC
-
SUCA_PIG
A:
[15-310]
--
L
Y
V
D
K
N
T
K
V
I
C
Q
G
F
T
G
K
Q
G
T
F
H
S
Q
Q
A
L
E
Y
G
T
N
L
V
G
G
T
T
P
G
K
G
G
K
T
H
L
G
L
P
V
F
N
T
V
K
E
A
K
E
Q
T
G
A
T
A
S
V
I
Y
V
P
P
P
F
A
A
A
A
I
N
E
A
I
D
A
E
V
P
L
V
V
C
I
T
E
G
I
P
Q
Q
D
M
V
R
V
K
H
R
L
L
R
Q
G
K
-
T
R
L
I
G
P
N
C
P
G
V
I
N
P
G
E
C
K
I
G
I
M
P
G
H
I
H
K
K
G
R
I
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
H
Q
T
T
Q
V
G
L
G
Q
S
L
C
V
G
I
G
G
D
P
F
N
G
T
D
F
T
D
C
L
E
I
F
L
N
D
P
A
T
E
G
I
I
L
I
G
E
I
G
G
N
A
E
E
N
A
A
E
F
L
K
Q
H
NSGP
K
S
K
P
V
V
S
F
I
A
G
L
T
A
P
P
G
R
R
M
G
H
A
G
A
I
I
A
G
G
K
G
G
A
K
E
K
I
T
A
L
Q
S
A
G
V
V
V
S
M
S
P
A
Q
L
G
T
T
I
Y
K
E
F
E
K
R
K
M
-
9
PsiBlast_PDB
90.14
61%
-83
- C3 -
-
4XX0
2
SUCA_PIG
A:
[9-303]
--
L
Y
V
D
K
N
T
K
V
I
C
Q
G
F
T
G
K
Q
G
T
F
H
S
Q
Q
A
L
E
Y
G
T
N
L
V
G
G
T
T
P
G
K
G
G
K
T
H
L
G
L
P
V
F
N
T
V
K
E
A
K
E
Q
T
G
A
T
A
S
V
I
Y
V
P
P
P
F
A
A
A
A
I
N
E
A
I
D
A
E
V
P
L
V
V
C
I
T
E
G
I
P
Q
Q
D
M
V
R
V
K
H
R
L
L
R
Q
G
K
-
T
R
L
I
G
P
N
C
P
G
V
I
N
P
G
E
C
K
I
G
I
M
P
G
H
I
H
K
K
G
R
I
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
H
Q
T
T
Q
V
G
L
G
Q
S
L
C
V
G
I
G
G
D
P
F
N
G
T
D
F
T
D
C
L
E
I
F
L
N
D
P
A
T
E
G
I
I
L
I
G
E
I
G
G
N
A
E
E
N
A
A
E
F
L
K
Q
H
NSGP
K
S
K
P
V
V
S
F
I
A
G
L
T
A
P
P
G
R
R
M
G
H
A
G
A
I
I
A
G
G
K
G
G
A
K
E
K
I
T
A
L
Q
S
A
G
V
V
V
S
M
S
P
A
Q
L
G
T
T
I
Y
K
E
F
E
K
R
K
--
10
PsiBlast_PDB
90.03
61%
-84
- C3 -
-
5CAE
3
SUCA_PIG
A:
[9-303]
--
L
Y
V
D
K
N
T
K
V
I
C
Q
G
F
T
G
K
Q
G
T
F
H
S
Q
Q
A
L
E
Y
G
T
N
L
V
G
G
T
T
P
G
K
G
G
K
T
H
L
G
L
P
V
F
N
T
V
K
E
A
K
E
Q
T
G
A
T
A
S
V
I
Y
V
P
P
P
F
A
A
A
A
I
N
E
A
I
D
A
E
V
P
L
V
V
C
I
T
E
G
I
P
Q
Q
D
M
V
R
V
K
H
R
L
L
R
Q
G
K
-
T
R
L
I
G
P
N
C
P
G
V
I
N
P
G
E
C
K
I
G
I
M
P
G
H
I
H
K
K
G
R
I
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
H
Q
T
T
Q
V
G
L
G
Q
S
L
C
V
G
I
G
G
D
P
F
N
G
T
D
F
T
D
C
L
E
I
F
L
N
D
P
A
T
E
G
I
I
L
I
G
E
I
G
G
N
A
E
E
N
A
A
E
F
L
K
Q
H
NSGP
K
S
K
P
V
V
S
F
I
A
G
L
T
A
P
P
G
R
R
M
G
H
A
G
A
I
I
A
G
G
K
G
G
A
K
E
K
I
T
A
L
Q
S
A
G
V
V
V
S
M
S
P
A
Q
L
G
T
T
I
Y
K
E
F
E
K
R
K
--
3
PsiBlast_PDB
88.90
70%
-102
- C3 -
-
1CQI
1
SUCD_ECOLI
A:
[1-286]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
-------
25
PsiBlast_CBE
88.25
70%
-102
- C3 -
-
1CQI
1
SUCD_ECOLI
D:
[1-286]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
N
C
P
G
V
I
T
P
G
E
C
K
I
G
I
Q
P
G
H
I
H
K
P
G
K
V
G
I
V
S
R
S
G
T
L
T
Y
E
A
V
K
Q
T
T
D
Y
G
F
G
Q
S
T
C
V
G
I
G
G
D
P
I
P
G
S
N
F
I
D
I
L
E
M
F
E
K
D
P
Q
T
E
A
I
V
M
I
G
E
I
G
G
S
A
E
E
E
A
A
A
Y
I
K
E
H
----
V
T
K
P
V
V
G
Y
I
A
G
V
T
A
P
K
G
K
R
M
G
H
A
G
A
I
I
A
G
G
K
G
T
A
D
E
K
F
A
A
L
E
A
A
G
V
K
T
V
R
S
L
A
D
I
G
E
A
L
K
T
V
-------
55
Fugue
55.69
67%
-129
- C3 -
-
2SCU
1
SUCD_ECOLI
A:
[1-119]
-
S
I
L
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
55.51
66%
-129
- C3 -
-
2SCU
1
SUCD_ECOLI
A:
[1-119]
S
I
L
-
I
D
K
N
T
K
V
I
C
Q
G
F
T
G
S
Q
G
T
F
H
S
E
Q
A
I
A
Y
G
T
K
M
V
G
G
V
T
P
G
K
G
G
T
T
H
L
G
L
P
V
F
N
T
V
R
E
A
V
A
A
T
G
A
T
A
S
V
I
Y
V
P
A
P
F
C
K
D
S
I
L
E
A
I
D
A
G
I
K
L
I
I
T
I
T
E
G
I
P
T
L
D
M
L
T
V
K
V
K
L
D
E
A
G
--
V
R
M
I
G
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------