@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSN5: (2017-12-09 )
MKVQPNDYSKIYDIAVIGGGINGVGIANDAVGRGLSVFLCEKDDLASHTSSASSKLIHGGLRYLEYKEFRLVREALAEREVLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLGKREKLLGSNRIYFKEDSPLKPAITRGFEYSDCTVDDARLVVLNALQAKEKGAKVVTRKRCVKAYRQQELWYLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHIVVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLTVTNSHFKKQLTRADIVSQYSGVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGKITTYRKLAEAALEHLAPFFNDMAEEWTADDPLPGAENWTTLEDLINQIKTRVSGISDSLANRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLGLAFDEKQVKVLEAYLSERRLKDDAA
Atome Classification :
(20 SA)
.........10........20........30........40.-.......50........60..--------..-....70........80......------..90.......----.100..----.....110----.......120-----....-....130...----...---.--140..---....-..150.......160.......170.......180-....-...190....--...200.......210.......220.......230.......-..240---------..-...-..250..---..--.-..260.......270......----------------.280.......290.......300......-.310-........320...------------....330.......340.......350......---.---360.......370.......380-----.......390..--.-...---------.400...---.---....410-..--......420.......---430.......440.......--450..-.....460.......470.......480-...-.-.---..490.......500...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKVQPNDY
S
K
I
Y
D
I
A
V
IGGGINGVGIA
N
D
AVGRG
L
S
V
F
L
CEK-
D
D
LASHTSSA
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
Y
K
E
F
R
L
V
R
E
A
L
A
E
R
E
V
L
L
AKAP------
H
I
I
K
P
M
R
F
IMP----HRPHL
R
----
P
A
W
L
I
R
A
G
----
L
F
F
Y
D
HLG
K
------
R
E
K
L-LGSN
R
I
Y
FKE----DSP---L--K
P
-
A
I
---TRGF-EYSDCTVDD
A
R
L
V
V
L
N
A
L
Q
AKEKG
A
K
V
V
T
R
K
R
C
V
K
-
A
Y
R
Q-QE
L
W
Y
L
E
LQS--GA
E
F
Y
Q
V
R
A
K
A
I
VNAA
G
P
W
V
E
E
I
I
SENLNLSS
P
Y
--
Q
I
R
L
IQG-
S
H
I
V
V
---------
P
K
-
L
Y
D
-
C
H
K
A
F
IM---QN--E-D
R
R
I
V
F
AIPYL
E
K
Y
T
LIGTTD----------------QEYTGDP
Q
K
V
E
I
T
D
V
E
I
D
Y
L
L
T
VT
N
S
H
F
K
K
-
Q
L
T
--
R
A
D
I
V
S
Q
YSG
V
R
A
L------------CDDESDNPS
A
I
TR
D
Y
T
L
A
L
QAEDKTT
P
L
L
S
VFG---G---K
I
T
T
Y
R
K
L
A
E
A
A
L
E
H
L
A
P
F
F
N
D
M
-----
A
E
EWTADDPLPG--A-ENW---------
T
T
-
L
E
D
L
---
I
---
N
Q
I
K
T
R
--VS--G
I
S
D
S
L
A
N
R
W
A
H
A
Y
G
T
---
R
V
W
N
M
L
K
E
R
N
A
I
E
Q
L
G
Q
H
FG--
H
D
L
F
E
-
C
E
V
R
Y
L
C
EYEWAH
T
A
E
D
I
L
W
R
R
SKLGLA-F
D
E
-
K
-
Q
---
V
K
V
L
E
A
Y
L
S
E
R
RLKDDAA
54
HHSearch
77.33
55%
-15
- C1 -
-
2QCU
9
GLPD_ECOLI
B:
[2-500]
---------
E
T
K
D
L
I
V
I
G
G
G
I
N
G
A
G
I
A
A
D
A
A
G
R
G
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
A
I
E
G
----------
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
-
M
W
L
N
A
-
D
Q
Q
S
R
V
S
Q
W
L
V
E
Y
T
Q
Q
R
L
S
L
A
---
4
PsiBlast_PDB
70.43
53%
-8
- C1 -
-
2R4E
17
GLPD_ECOLI
A:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
3
PsiBlast_PDB
70.13
53%
-9
- C1 -
-
2R46
23
GLPD_ECOLI
A:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
2
PsiBlast_PDB
70.03
53%
-6
- C1 -
-
2R45
21
GLPD_ECOLI
A:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
5
PsiBlast_PDB
69.79
53%
-7
- C1 -
-
2R4J
20
GLPD_ECOLI
A:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
21
PsiBlast_CBE
69.71
53%
-4
- C1 -
-
2R4E
14
GLPD_ECOLI
B:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
24
PsiBlast_CBE
69.34
53%
-4
- C1 -
-
2QCU
9
GLPD_ECOLI
B:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
23
PsiBlast_CBE
69.00
53%
-8
- C1 -
-
2R45
10
GLPD_ECOLI
B:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
1
PsiBlast_PDB
68.64
53%
-5
- C1 -
-
2QCU
20
GLPD_ECOLI
A:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
22
PsiBlast_CBE
68.45
53%
-4
- C1 -
-
2R46
14
GLPD_ECOLI
B:
[27-491]
----------------------------------
L
S
V
L
M
L
E
A
-
Q
D
L
A
C
A
T
S
S
A
S
S
K
L
I
H
G
G
L
R
Y
--------
L
E
-
H
Y
E
F
R
L
V
S
E
A
L
A
E
R
E
V
L
L
K
M
A
P
------
H
I
A
F
P
M
R
F
R
L
P
----
H
R
P
H
L
R
----
P
A
W
M
I
R
I
G
----
L
F
M
Y
D
H
L
G
K
------
R
T
S
L
-
P
G
S
T
G
L
R
F
G
A
----
N
S
V
---
L
--
K
P
-
E
I
---
K
R
G
F
-
E
Y
S
D
C
W
V
D
D
A
R
L
V
L
A
N
A
Q
M
V
V
R
K
G
G
E
V
L
T
R
T
R
A
T
S
-
A
R
R
E
-
N
G
L
W
I
V
E
A
E
D
ID
T
G
K
K
Y
S
W
Q
A
R
G
L
V
N
A
T
G
P
W
V
K
Q
F
F
D
D
G
M
H
L
P
S
P
Y
--
G
I
R
L
I
K
G
-
S
H
I
V
V
---------
P
R
-
V
H
T
-
Q
K
Q
A
Y
I
L
---
Q
N
--
E
-
D
K
R
I
V
F
V
I
P
W
M
D
E
F
S
I
I
G
T
T
D
----------------
V
E
Y
K
G
D
P
K
A
V
K
I
E
E
S
E
I
N
Y
L
L
N
V
Y
N
T
H
F
K
K
-
Q
L
S
--
R
D
D
I
V
W
T
Y
S
G
V
R
P
L
------------
C
D
D
E
S
D
S
P
Q
A
I
T
R
D
Y
T
L
D
I
H
D
E
N
G
K
A
P
L
L
S
V
F
G
---
G
---
K
L
T
T
Y
R
K
L
A
E
H
A
L
E
K
L
T
P
Y
Y
Q
G
I
-----
G
P
A
W
T
K
E
S
V
L
P
G
--
G
-
A
I
E
---------
G
D
-
R
D
D
Y
---
A
---
A
R
L
R
R
R
--
Y
P
--
F
L
T
E
S
L
A
R
H
Y
A
R
T
Y
G
S
---
N
S
E
L
L
L
G
N
A
G
T
V
S
D
L
G
E
D
F
G
--
H
E
F
Y
E
-
A
E
L
K
Y
L
V
D
H
E
W
V
R
R
A
D
D
A
L
W
R
R
T
K
Q
G
M
W
-
L
N
A
-
D
-
Q
---
Q
S
R
V
S
Q
W
L
V
E
--------
55
HHSearch
57.38
29%
9
- C1 -
-
2RGH
1
?
A:
[28-546]
------
M
Q
Q
E
E
L
D
L
L
I
I
G
G
G
I
T
G
A
G
V
A
V
Q
A
A
A
S
G
I
K
T
G
L
I
E
M
-
Q
D
F
A
E
G
T
S
S
R
S
T
K
L
V
H
G
G
I
R
Y
--------
L
K
-
T
F
D
V
E
V
V
A
D
T
V
G
E
R
A
V
V
Q
G
I
A
P
------
H
I
P
K
P
D
P
M
L
L
P
----
I
Y
E
D
E
G
ATTF
N
M
F
S
V
K
V
A
----
M
D
L
Y
D
K
L
A
N
------
V
T
G
T
K
Y
E
N
Y
T
L
T
P
E
E
V
L
E
R
E
P
F
---
L
--
K
K
E
G
L
---
K
G
A
G
-
V
Y
L
D
F
R
N
N
D
A
R
L
V
I
D
N
I
K
K
A
A
E
D
G
A
Y
L
V
S
K
M
K
A
V
G
-
F
L
Y
E
G
D
Q
I
V
G
V
K
A
R
D
LL
T
D
E
V
I
E
I
K
A
K
L
V
I
N
T
S
G
P
W
V
D
K
V
R
N
L
N
F
T
R
P
V
S
P
--
K
M
R
P
T
K
G
-
I
H
L
V
V
---------
D
A
-
K
K
L
P
V
P
Q
P
T
Y
F
---
D
T
GK
Q
-
D
G
R
M
V
F
A
I
P
R
E
N
-
K
T
Y
F
G
T
T
D
----------------
T
D
Y
Q
G
D
F
T
D
P
K
V
T
Q
E
D
V
D
Y
L
L
D
V
I
N
H
R
Y
P
E
A
N
I
T
--
L
A
D
I
E
A
S
W
A
G
L
R
P
L
------------
L
I
G
-----------
S
S
L
E
R
E
----
P
D
G
L
L
T
L
S
G
---
G
---
K
I
T
D
Y
R
K
M
A
E
G
A
L
R
L
I
R
Q
L
L
K
E
E
YG
I
E
T
K
E
I
D
S
K
K
Y
Q
I
S
G
--
G
N
F
D
P
---------
T
K
-
L
E
E
T
V
T
E
L
---
A
K
E
G
V
A
--
A
---
G
L
E
E
E
D
A
T
Y
I
A
D
F
Y
G
T
---
N
A
R
R
I
F
E
L
A
K
E
---
M
-
A
P
Y
P
GL
S
L
A
E
S
-
A
R
L
R
Y
G
L
E
E
E
M
V
L
A
P
G
D
Y
L
I
R
R
T
N
H
L
-
L
-
F
E
R
D
Q
-
L
DEI
K
Q
P
V
I
D
A
I
A
E
Y
F
G
W
T
E
E
-
53
HHSearch
51.50
30%
4
- C1 -
-
3DA1
1
?
A:
[13-525]
-----
E
M
S
E
K
Q
L
D
L
L
V
I
G
G
G
I
T
G
A
G
I
A
L
D
A
Q
V
R
G
I
Q
T
G
L
V
E
M
-
N
D
F
A
S
G
T
S
S
R
S
T
K
L
V
H
G
------------------------
V
G
K
E
R
A
I
V
Y
E
N
A
P
------
H
V
T
T
P
E
W
M
L
L
P
----
I
F
K
-----------------------------------------
R
Y
M
L
N
E
K
Q
T
L
E
K
E
P
L
---
L
--
R
K
E
N
L
---
K
G
G
G
-
I
Y
V
E
Y
R
T
D
D
A
R
L
T
L
E
I
M
K
E
A
V
A
R
G
A
V
A
L
N
Y
M
K
V
E
S
-
F
I
Y
D
Q
G
K
V
V
G
V
V
A
K
D
RL
T
D
T
T
H
T
I
Y
A
K
K
V
V
N
A
A
G
P
W
V
D
T
L
R
E
K
D
R
S
K
-
H
G
K
--
Y
L
K
L
S
K
G
-
V
H
L
V
V
---------
D
Q
-
S
R
F
P
L
R
Q
A
V
Y
F
---
D
T
E-
S
-
D
G
R
M
I
F
A
I
P
R
E
G
-
K
T
Y
I
G
T
T
D
----------------
T
F
Y
D
K
D
I
A
S
P
R
M
T
V
E
D
R
D
Y
I
L
A
A
A
N
Y
M
F
P
S
--
L
R
LT
A
D
D
V
E
S
S
W
A
G
L
R
P
L
------------
I
H
E
-----------
D
E
I
F
F
S
----
D
S
G
L
I
S
I
A
G
---
G
---
K
L
T
G
Y
R
K
M
A
E
R
T
V
D
A
V
A
Q
G
L
N
V
N
-----
E
P
C
T
T
A
A
I
R
L
S
G
--
G
L
A
E
G
---------
A
Q
G
F
P
R
F
---
L
D
E
A
S
R
K
G
A
K
--
L
---
G
F
D
A
D
E
V
R
R
L
A
K
L
Y
G
S
---
N
V
D
H
V
L
N
Y
A
Y
E
G
K
E
E
A
E
H
Y
G
L-
P
A
L
L
L
-
G
Q
L
Q
Y
G
V
E
Q
E
M
V
A
T
P
L
D
F
F
V
R
R
T
G
A
L
-
F
-
F
N
I
-
S
L
V
H
Q
W
K
E
A
V
L
R
W
M
A
E
E
F
S
W
T
E
E
-
8
PsiBlast_PDB
50.03
27%
20
- C1 -
-
2RGO
1
?
A:
[41-552]
---------------------------------
G
I
K
T
G
L
I
E
M
-
Q
D
F
A
E
G
T
S
S
R
S
T
K
L
V
H
G
G
I
R
Y
--------
L
K
-
T
F
D
V
E
V
V
A
D
T
V
G
E
R
A
V
V
Q
G
I
A
P
------
H
I
P
K
P
D
P
M
L
L
P
I
Y
ED
E
G
A
T
T
F
----
N
M
F
S
V
K
V
A
----
M
D
L
Y
D
K
L
A
N
VTGTKY
E
N
Y
T
-
L
T
P
E
E
V
L
E
R
E
----
P
F
L
---
K
--
K
E
-
G
L
---
K
G
A
G
-
V
Y
L
D
F
R
N
N
D
A
R
L
V
I
D
N
I
K
K
A
A
E
D
G
A
Y
L
V
S
K
M
K
A
V
G
F
L
Y
E
G
-
D
Q
I
V
G
V
K
A
R
D
LL
T
D
E
V
I
E
I
K
A
K
L
V
I
N
T
S
G
P
W
V
D
K
V
--
R
N
L
N
F
T
R
P
V
S
P
K
M
R
P
T
K
G
-
I
H
L
V
V
DAKKLPVP
Q
P
T
-
Y
F
D
-
T
G
K
-----------
Q
-
D
G
R
M
V
F
A
I
P
R
-
E
N
K
T
Y
F
G
T
T
D
----------------
T
D
Y
Q
G
D
F
T
D
P
K
V
T
Q
E
D
V
D
Y
L
L
D
V
I
N
H
R
Y
P
E
A
N
I
T
--
L
A
D
I
E
A
S
W
A
G
L
R
P
L
LIGNSGSDYNGG---------
T
I
S
R
G
S
S
L
----
E
R
E
P
D
G
L
L
T
L
S
G
---
G
---
K
I
T
D
Y
R
K
M
A
E
G
A
L
R
L
I
R
Q
L
---
L
-----
K
E
E
Y
G
I
E
T
K
E
I
D
--
S
-
K
K
Y
QISGGNFDP
T
K
-
L
E
E
T
---
V
---
T
E
L
A
K
E
G
V
A
A
--
G
L
E
E
E
D
A
T
Y
I
A
D
F
Y
G
T
N
A
R
R
I
F
E
L
A
K
E
-------
A
P
Y
P
G
--
L
S
L
A
E
S
A
R
L
R
Y
G
L
E
E
E
M
V
L
A
P
G
D
Y
L
I
R
R
T
----------------------------------
6
PsiBlast_PDB
49.58
29%
20
- C1 -
-
2RGH
1
?
A:
[55-516]
---------------------------------
G
I
K
T
G
L
I
E
M
-
Q
D
F
A
E
G
T
S
S
R
S
T
K
L
V
H
G
G
I
R
Y
--------
L
K
-
T
F
D
V
E
V
V
A
D
T
V
G
E
R
A
V
V
Q
G
I
A
P
------
H
I
P
K
P
D
P
M
L
L
P
I
Y
ED
E
G
A
T
T
F
----
N
M
F
S
V
K
V
A
----
M
D
L
Y
D
K
L
A
N
VTGTKY
E
N
Y
T
-
L
T
P
E
E
V
L
E
R
E
----
P
F
L
---
K
--
K
E
-
G
L
---
K
G
A
G
-
V
Y
L
D
F
R
N
N
D
A
R
L
V
I
D
N
I
K
K
A
A
E
D
G
A
Y
L
V
S
K
M
K
A
V
G
F
L
Y
E
G
-
D
Q
I
V
G
V
K
A
R
D
LL
T
D
E
V
I
E
I
K
A
K
L
V
I
N
T
S
G
P
W
V
D
K
V
--
R
N
L
N
F
T
R
P
V
SP
K
M
R
P
T
K
G
-
I
H
L
V
V
DAKKLPVP
Q
P
T
-
Y
F
D
-
T
G
K
-----------
Q
-
D
G
R
M
V
F
A
I
P
R
-
E
N
K
T
Y
F
G
T
T
D
----------------
T
D
Y
Q
G
D
F
T
D
P
K
V
T
Q
E
D
V
D
Y
L
L
D
V
I
N
H
R
Y
P
E
A
N
I
T
--
L
A
D
I
E
A
S
W
A
G
L
R
P
L
------------
L
I
G
-----------
S
S
L
----
E
R
E
P
D
G
L
L
T
L
S
G
---
G
---
K
I
T
D
Y
R
K
M
A
E
G
A
L
R
L
I
R
Q
L
---
L
-----
K
E
E
Y
G
I
E
T
K
E
I
D
--
S
-
K
K
Y
QISGGNFDP
T
K
-
L
E
E
T
---
V
---
T
E
L
A
K
E
G
V
A
A
--
G
L
E
E
E
D
A
T
Y
I
A
D
F
Y
G
T
N
A
R
R
I
F
E
L
A
K
E
M
------
A
P
Y
P
G
--
L
S
L
A
E
S
A
R
L
R
Y
G
L
E
E
E
M
V
L
A
P
G
D
Y
L
I
R
R
T
----------------------------------
7
PsiBlast_PDB
44.56
30%
28
- C1 -
-
3DA1
1
?
A:
[36-495]
----------------------------
D
A
Q
V
R
G
I
Q
T
G
L
V
E
M
-
N
D
F
A
S
G
T
S
S
R
S
T
K
L
V
H
G
------------------------
V
G
K
E
R
A
I
V
Y
E
N
A
P
------
H
V
T
T
P
E
W
M
L
L
P
I
---
F
K
--------------------------------------
R
-
Y
M
L
N
E
K
Q
T
L
E
----
K
E
P
---
L
LR
K
E
-
N
L
---
K
G
G
G
-
I
Y
V
E
Y
R
T
D
D
A
R
L
T
L
E
I
M
K
E
A
V
A
R
G
A
V
A
L
N
Y
M
K
V
E
S
F
I
Y
D
Q
-
G
K
V
V
G
V
V
A
K
D
RL
T
D
T
T
H
T
I
Y
A
K
K
V
V
N
A
A
G
P
W
V
D
T
L
R
E
K
D
R
S
K
H
G
K
Y
---
L
K
L
S
K
G
-
V
H
L
V
V
---------
D
Q
S
R
F
P
-
L
R
Q
A
V
Y
F
---
D
T
--
E
S
D
G
R
M
I
F
A
I
P
R
-
E
G
K
T
Y
I
G
T
T
D
----------------
T
F
Y
D
K
D
I
A
S
P
R
M
T
V
E
D
R
D
Y
I
L
A
A
A
N
Y
M
F
P
S
L
R
L
T
--
A
D
D
V
E
S
S
W
A
G
L
R
P
L
------------
I
H
E
-----------
D
E
I
F
F
S
----
D
S
G
L
I
S
I
A
G
---
G
---
K
L
T
G
Y
R
K
M
A
E
R
T
V
D
A
V
A
Q
G
L
N
V
N
-----
E
P
C
T
T
A
A
I
R
L
S
G
GL
A
-
E
G
A
---------
Q
G
-
F
P
R
F
---
L
---
D
E
A
S
R
K
--
G
A
K
L
G
F
D
A
D
E
V
R
R
L
A
K
L
Y
G
S
---
N
V
D
H
V
L
N
Y
A
Y
E
G
K
E
E
A
E
H
Y
G
L-
P
A
L
L
L
-
G
Q
L
Q
Y
G
V
E
Q
E
M
V
A
T
P
L
D
F
F
V
R
R
T
----------------------------------
9
PsiBlast_PDB
42.51
21%
-20
- C1 -
-
3DME
4
?
A:
[6-368]
------------
D
C
I
V
I
G
A
G
V
V
G
L
A
I
A
R
A
L
A
A
G
G
H
E
V
L
V
A
E
A
A
E
G
I
G
T
G
T
S
S
R
N
S
E
V
I
H
A
G
I
Y
Y
PADS
L
K
A
R
L
C
-
V
R
G
K
H
L
L
Y
E
Y
C
A
A
R
G
V
-----------------------------
P
H
Q
R
----
L
G
K
L
I
V
A
T
S
D
A
E
A
S
Q
L
D
S
I
A
R
------
R
A
G
A
-
N
G
V
D
D
L
Q
H
I
D
----
G
A
A
A
R
R
L
--
E
P
-
A
L
HCT
A
A
L
V
-
S
P
S
T
G
I
V
D
S
H
A
L
M
L
A
Y
Q
G
D
A
E
S
D
G
A
Q
L
V
F
H
T
P
L
I
A
-
G
R
V
R
-
P
E
G
G
F
E
L
D
F
G
--
G
A
E
P
M
T
L
S
C
R
V
L
I
N
A
A
G
------------
L
H
A
P
G
--
L
A
R
R
I
E
G
I
P
R
D
S
I
---------
P
P
-
E
Y
L
-
C
K
G
S
Y
F
T
L
A
G
R
A
--
P
-
F
S
R
L
I
Y
P
V
P
Q
H
A
G
L
G
V
H
L
T
L
D
LGG
Q
A
K
F
G
P
D
T
E
W
I
AT
E
D
Y
T
L
D
P
R
R
A
-------
D
V
F
Y
A
A
V
R
S
Y
W
P
A
--
L
P
--
D
G
A
L
A
P
G
Y
T
G
I
R
----------------
P
K
I
S
G
P
H
E
P
A
A
D
F
A
I
A
G
P
A
S
H
G
V
A
G
L
V
N
L
Y
G
IES
P
---
G
L
T
A
S
L
A
I
A
E
E
T
L
A
R
L
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
38.94
41%
-244
- C1 -
-
2BXR
1
AOFA_HUMAN
A:
[13-54]
----------
M
F
D
V
V
V
I
G
G
G
I
S
G
L
S
A
A
K
L
L
T
E
Y
G
V
S
V
L
V
L
E
A
-
R
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
38.74
17%
-23
- C1 -
-
4YSH
1
GLYOX_GEOKA
A:
[2-355]
--------
T
H
R
Y
D
V
A
I
V
G
G
G
V
I
G
A
A
I
G
F
E
L
A
K
R
R
H
R
V
A
I
F
E
K
-
G
T
M
G
S
G
A
S
S
A
A
A
G
M
L
G
A
Q
S
E
F
--------
S
T
S
S
P
L
V
P
L
A
L
Q
S
R
A
L
M
P
A
L
A
E
E
L
R
E
R
TGID
I
G
L
V
E
K
G
L
I
K
L
----
A
T
T
E
E
-----
E
A
D
D
L
Y
-------
R
H
Y
T
F
W
R
G
------
I
-
G
E
--
P
V
Q
W
L
T
K
G
E
A
L
E
M
E
P
R
---
L
--
A
E
-
A
L
---
A
G
A
M
Y
I
P
G
D
G
Q
V
S
A
P
D
L
A
A
A
L
A
Y
A
A
A
S
A
G
A
C
L
Y
E
Y
T
E
V
F
D
-
I
R
S
D
-
S
S
G
H
V
L
-
D
T
---
T
--
G
G
T
F
A
A
E
A
V
V
I
A
S
G
A
W
A
A
R
L
G
A
R
V
G
---
L
S
L
--
S
V
Y
P
V
K
G
-
E
C
V
M
V
---------
R
A
-
P
V
P
-
L
L
Q
T
T
V
F
---
A
------
K
N
G
C
Y
I
V
P
K
S
G
N
R
L
L
I
G
A
T
S
----------------
T
P
G
T
---
F
D
R
R
V
S
A
G
G
V
M
N
L
L
H
R
A
A
H
L
V
P
D
--
I
E
--
Q
A
E
W
V
A
S
W
S
G
I
R
P
Q
------------
T
E
D
G
---------
L
P
Y
L
G
E
H
P
--
E
R
R
G
L
F
V
A
A
G
---
H
YRN
G
I
L
L
S
P
L
T
G
L
L
V
A
D
L
V
E
R
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
38.18
41%
-204
- C1 -
-
2Z5X
2
AOFA_HUMAN
A:
[2-35]
----------
M
F
D
V
V
V
I
G
G
G
I
S
G
L
S
A
A
K
L
L
T
E
Y
G
V
S
V
L
V
L
E
A
-
R
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
38.17
41%
-250
- C1 -
-
2BXR
1
AOFA_HUMAN
B:
[13-54]
----------
M
F
D
V
V
V
I
G
G
G
I
S
G
L
S
A
A
K
L
L
T
E
Y
G
V
S
V
L
V
L
E
A
-
R
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------