@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VSV2: (2017-12-10 )
MALTSIAPVINQYGVTVSTYSEIVEHLKEKYREIYGQDVYLENDSQDGQWIGVIARVVADCNAAVADVYSSMSPSTAGTDALSRNVKINGIRRAVATKSTVSVVLVGAAGTIINNGIVSDKNNNRWLLPTQVVIPPEGEIFVAASAEKPGAILALPNSITTISTPTRGWQSVNNPQASTLGAPVESNVKLRQRQALSTAIPSRSYTEGILGALFSLDGVSRCKVYENKKSFVDPLELPPNSLSVVVAGGDDQLIAETIRVKKAPGCDLYGNTTVIRPTVYGDPVEIQYWRPVQKSIGLRFELTTNSDYTVDIGEQIKSATADYINQLDIGDRIAINKLYVPAGLYGALDARSYEIESLQLTVDGVPVEGDYTLDFNAVAYCDSDDIEISVAGGG
Atome Classification :
(18 SA)
---------.........10....--....20.........30.....----...40--.........50.---...-----....60........70........-80..-..---------....90........100......-----.110--........120.------..-..--...130..---..-..-.---------------------------------------------------------------------------------------------------------140...---....150..-------------------...-.-..160..-.....170..--------.------....180.-......190------..--......200--------..-.-....-210..-.-....220.-----......230.....-..240..-.....-250------.--------........---260.......270...----....280......--.290--.......--.300----------......----.310..-...-------....320....--.---------------..330--.......340.......350.-......360.-.-.....370.....--..380.......390--...---------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------MA
L
T
S
I
A
P
V
I
N
QYGV--
T
V
S
T
Y
-
S
E
I
V
E
H
L
K
E
K
Y
R
E
I
YG----Q
D
V
Y
---LENDSQD
G
Q
W
I
G
---
V
I
A
-----
R
V
V
ADC
N
A
A
V
A
D
V
Y
S
SMSPSTAG
T
-
D
A
LS-RN---------
V
K
I
N
G
I
R
RAVATK
S
T
V
S
V
V
L
VGA-----AG
T
---
I
INNGIVSDK-N------N
N
-
R
W
--
L
L
P
T
Q
V
V
I---PP-EG-
E
---------------------------------------------------------------------------------------------------------
I
F
V
A
AS---AEKP
G
A
-
I
L
-------------------ALP-N-S
I
T
TIST-PTRGWQSVNN--------P------QASTLGAP-VESNV
K
L
R
-------
Q
R
--
Q
A
L
S
T
AIPS--------RS-
Y
-
T
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G
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G
A
L
F
-S-LDG
V
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R
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-----VYENKKSFVDPLEL-PPN
S
L
S
V
-
V
V
AGG-D--------
D
--------
Q
L
I
A
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T
I
R---VKKAPGCDLYGN
T
T
V
I
----
R
PTVYGDP
V
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--WR
P
---
V
Q
K
SI
G
L
--
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F
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L
----------TTNS
D
Y
----
T
V
--
D
I
-
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E
Q
-------
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K
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A
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A
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Q--L---------------DIG
D
R
--
I
A
I
N
K
L
YVPAG
L
Y
GALDAR
S
Y
-
E
I
E
S
L
Q
L
T
VD-
G
-
V
PVEG
D
Y
T
L
D
F
N
A
--
V
A
Y
CDSD
D
I
E
I
S
VA---GGG---------------
23
Fugue
69.65
18%
-
- C- -
-
4C0H
-
CLP1_YEAST
A:
[19-445]
------GDN
E
W
H
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D
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--
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L
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------
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---
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---------------------------------------------------------------------------------------------------------
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--
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---------------
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--
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L
L
PV
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G
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LPS
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A
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24
Fugue
61.72
16%
16
* C5 *
-
5DIY
1
?
B:
[2-473]
---------
E
Y
F
R
Y
R
G
I
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G
F
Y
G
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PW
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H
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---
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---------
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---
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---------------------------------------------------------------------------------------------------------
Q
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---
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CPTFYCNDPNLEYLRILGQ
R
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--------
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------
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DNYPVND
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--------
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--------
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A
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---
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---
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R
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----------
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Q
T
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----
Y
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--
R
L
-
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DSKFFWE
I
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L
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E
Y
K
L
W
--
T
---------------
D
Y
L
D
Q
AM
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L
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A
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L
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A
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L
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R
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F
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--
Q
V
L
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S
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V
S
I
E
L
Q
A
E
---
G
K
E
WTALPPGIVR-----
19
HHSearch
48.25
18%
-54
- C7 -
-
5CES
-
?
A:
[2-91]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
---
G
I
V
P
Y
Q
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--
K
A
Q
L
----------
Y
L
F
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A
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L
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A
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-------
A
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-
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---------------
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L
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--
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--
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D
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--
A
A
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C
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Y
A
I
T
L
G
G
----------------------
25
Fugue
46.22
14%
23
- C2 -
-
5LJ3
-
?
H:
[11-481]
IKFQRENWE
M
I
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V
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P
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N
L
T
M
------------
D
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----
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---
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---
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N
N
----
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-
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E
T
---------
L
A
K
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L
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F
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Q
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F
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K
D
Y
V
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C
G
N
-----
I
L
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---
C
L
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I
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V
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------
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E
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--
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L
Q
I
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L
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L
---
L
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N
-
S
---------------------------------------------------------------------------------------------------------
L
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L
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---
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----
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-------------------
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W
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D
M
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--------
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------
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Q
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L
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F
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---
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EDMRSRL--------
27
Fugue
43.04
15%
42
- C5 -
-
1G9M
15
?
G:
[5-321]
---------------
E
V
V
L
V
N
V
T
E
--
N
F
N
M
W
K
N
D
M
V
E
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I
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W
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----
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K
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F
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-----------------------
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---
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T
V
Q
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L
L
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A
-
E
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---------------------------------------------------------------------------------------------------------
V
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NF-
T
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K
T
-
I
I
-------------------
V
Q
L
-
N
-
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V
E
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T
G
A
G
H
C
N
I
S
------------------------------
R
A
K
-------
W
N
--
N
T
L
K
Q
I
A
S
K
--------
L
R
-
E
-
Q
F
G
-------------------------
N
N
K
T
I
I
F
K
Q
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-------------
G
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--------
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--------
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---
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N
--------------
G
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----------
K
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--------
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--
N
M
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Q
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-------
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K
A
M
Y
A
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--
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---------------
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--
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G
L
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D
N
W
R
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K
--
Y
K
V
V
K
I
E
----------------------------
29
Fugue
42.21
14%
68
- C1 -
-
3TNF
4
?
B:
[3-381]
-----------
L
D
E
Y
E
Q
A
I
K
R
A
Q
E
--
N
I
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K
G
-
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K
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K
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-----
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A
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L
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A
H
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A
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---
N
K
-
D
Q
-
E
---------------------------------------------------------------------------------------------------------
V
V
E
H
E
G
Q
F
Y
L
L
Q
K
G
Q
-
W
D
-------------------
A
I
K
-
N
-
N
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A
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L
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K
-
A
Q
K
D
Y
S
Q
S
K
H
--------
D
------
L
A
T
I
K
M
E
A
-
L
I
H
K
L
S
L
E
-------
M
E
--
K
Q
L
E
T
I
N
N
L
--------
I
M
-
S
-
T
D
P
K
-
E
N
E
E
A
-
T
-
K
L
L
H
K
H
N
G
-----
L
N
L
K
L
A
N
L
Q
D
M
L
A
V
-
H
R
K
E
K
S
F
-
F
N
E
K
G
-----------------------
E
E
V
T
---
S
L
N
D
A
H
Y
V
I
G
K
D
Q
Q
L
F
----
N
L
G
--
G
K
F
Y
P
I
H
K
--
E
Q
K
---
I
L
E
K
D
G
K
--
F
Y
L
L
----------
K
Q
G
E
D
W
----
E
S
IK
D
S
-
P
E
K
-------
Q
K
K
A
E
H
D
F
H
K
L
--
Q
---------------
Y
E
T
P
M
--
T
V
K
K
L
V
H
H
N
K
G
L
E
T
T
I
H
K
E
R
V
-
E
E
T
K
Q
Q
L
E
D
N
-
G
-
K
E
--------------------
K
I
E
I
A
N
N
---
I
S
K
---------------
2
PsiBlast_PDB
36.31
28%
-63
- C6 -
-
3KO1
1
?
A:
[357-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
R
K
-----
V
G
E
D
K
M
V
F
V
E
G
A
K
--
N
P
K
S
I
S
I
-
L
I
R
G
G
-
L
--------
E
--------
R
L
V
D
E
T
E
R
---
A
L
R
----
D
A
L
G
T
V
A
D
V
I
K
D
G
R
A
I
A
G
G
G
A
V
E
I
E
I
--
A
K
K
---
L
R
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
36.01
28%
-78
- C6 -
-
3J1E
-
?
A:
[357-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
R
K
-----
V
G
E
D
K
M
V
F
V
E
G
A
K
--
N
P
K
S
I
S
I
-
L
I
R
G
G
-
L
--------
E
--------
R
L
V
D
E
T
E
R
---
A
L
R
----
D
A
L
G
T
V
A
D
V
I
K
D
G
R
A
I
A
G
G
G
A
V
E
I
E
I
--
A
K
K
---
L
R
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
34.44
31%
-39
- C6 -
-
1JQ3
1
SPEE_THEMA
A:
[56-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
V
F
-
A
-
L
D
G
I
T
M
T
T
EKD
E
F
M
Y
H
E
M
L
A
H
V
-
P
M
F
L
-
H
P
N
P
K
K
V
L
I
I
G
G
G
-
D
--------
G
--------
G
T
L
R
E
V
L
K
HDS
V
E
K
A
I
L
C
E
V
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
34.11
28%
-47
* C6 *
-
3J1F
1
?
A:
[357-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
R
K
-----
V
G
E
D
K
M
V
F
V
E
G
A
K
--
N
P
K
S
I
S
I
-
L
I
R
G
G
-
L
--------
E
--------
R
L
V
D
E
T
E
R
---
A
L
R
----
D
A
L
G
T
V
A
D
V
I
K
D
G
R
A
I
A
G
G
G
A
V
E
I
E
I
--
A
K
K
---
L
R
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
33.94
31%
-39
- C6 -
-
1INL
-
SPEE_THEMA
A:
[56-134]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
V
F
-
A
-
L
D
G
I
T
M
T
T
EKD
E
F
M
Y
H
E
M
L
A
H
V
-
P
M
F
L
-
H
P
N
P
K
K
V
L
I
I
G
G
G
-
D
--------
G
--------
G
T
L
R
E
V
L
K
HDS
V
E
K
A
I
L
C
E
V
D
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
31.80
32%
23
- C6 -
-
4RCK
-
?
A:
[17-68]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
H
R
D
M
M
L
--
V
V
D
L
SGSMAEEDMK
T
S
N
G
D
F
-----
V
--
D
R
-
L
T
A
-------
V
K
Q
V
V
S
D
F
I
D
Q
--
R
---------------
K
-
G
D
R
--
L
G
L
----------------------------------------------------------------------------------
18
HHSearch
31.64
11%
23
* C7 *
-
3H2T
-
BP06_BPT4
B:
[342-474]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
D
Y
-
D
T
F
V
S
E
R
F
G
S
I
I
Q
A
V
Q
-----
T
F
T
D
S
T
K
---------
P
G
Y
A
F
I
-
A
A
K
P
K
-
S
--------
G
LYLT
T
V
Q
R
E
D
I
K
N
Y
L
K
---
D
Y
N
L
A
P
I
T
----------------------
P
S
I
--
I
S
P
---
N
Y
L
F
I
K
T
--
N
L
K
V
----------
T
Y
A
L
N
K
LQES
E
Q
--
W
L
-
E
G
Q
-------
I
I
D
K
I
D
R
Y
Y
T
E
DV
E
---------------
I
F
N
S
S
--
F
A
K
S
K
M
L
T
Y
V
--
D
D
A
-
D
H
-
S
-----------------------------------------------------------------
15
HHSearch
25.90
11%
0
- C- -
-
5IV5
-
BP06_BPT4 (first)
A:
[10--183]
------------
L
T
R
T
A
N
A
I
P
E
I
F
--
V
G
G
T
F
-
A
E
I
K
Q
N
L
I
E
W
L
N
G
Q
-
N
----
E
F
L
D
Y--
D
F
E
G
S
R
L
N
V
L
C
D
---
L
L
A
-----
Y
N
T
L
Y
I
Q
Q
F
G
N
A
A
V
Y
E
S
F
M
R
T
A
N
L
R
S
S
V
V
-
Q
A
---------
A
Q
D
N
G
Y
L
P
T
S
K
S
A
A
Q
T
E
I
M
L
T
C
T
D
ALNR
N
Y
I
---
T
I
P
R
G
T
R
F
L
A
Y
A
KDTSV
N
P
Y
-
N
F
--
V
S
R
E
D
V
I
A
---
I
R
D
K
N
N
Q
Y
F
P
R
L
K
L
A
Q
G
R
I
V
R
T
E
I
I
Y
D
KL
T
P
I
I
IYDKNIDRNQ
V
K
L
Y
V
DG
A
E
W
I
NWTRKSMVHAGSTST
I
Y
Y
M
R
E
T
IDG
N
T
E
F
Y
F
G
E
G
E
I
S
V
N
ASEGA
L
T
A
N
Y
I
G
G
L
K
P
TQN
S
T
I
V
I
E
Y
--
I
S
T
N
G
A
D
A
N
-------------------
G
A
V
-
G
F
S
Y
A
D
T
L
T
-
N
I
T
V
I
N
I
N
E
N
--------
P
NDDPDF
V
G
A
D
G
G
G
D
-
P
E
D
I
E
R
I
R
-------
E
L
--
G
T
I
K
R
E
T
Q
Q
--------
R
C
V
T
-
A
T
D
Y
-
D
T
F
V
S
E
R
-
F
G
S
I
I
Q
A
-------
V
Q
T
F
T
D
S
-----
T
-
K
P
G
Y
A
F
I
-
A
A
K
P
K
-
S
GLYLT
T
V
Q
R
--------
E
D
I
K
N
Y
L
K
---
D
Y
N
L
A
P
I
T
----------------------
P
S
I
--
I
S
P
---
N
Y
L
F
I
K
T
--
N
L
K
V
----------
T
Y
A
L
N
K
LQES
E
Q
--
W
L
-
E
G
Q
-------
I
I
D
K
I
D
R
Y
Y
T
E
DV
E
---------------
I
F
N
S
S
--
F
A
K
S
K
M
L
T
Y
V
--
D
D
A
D
H
S
-
V
I
-
G
S
-------------------------------------------------------------
14
HHSearch
25.90
11%
0
- C- -
-
5IV5
-
BP06_BPT4 (first)
Y:
[12-478]
--------------
R
T
A
N
A
I
P
E
I
F
--
V
G
G
T
F
-
A
E
I
K
Q
N
L
I
E
W
L
N
G
Q
-
N
----
E
F
L
D
Y--
D
F
E
G
S
R
L
N
V
L
C
D
---
L
L
A
-----
Y
N
T
L
Y
I
Q
Q
F
G
N
A
A
V
Y
E
S
F
M
R
T
A
N
L
R
S
S
V
V
-
Q
A
---------
A
Q
D
N
G
Y
L
P
T
S
K
S
A
A
Q
T
E
I
M
L
T
C
T
DALNR
N
Y
I
---
T
I
P
R
G
T
R
F
L
A
Y
A
KDTSVN
P
Y
-
N
F
--
V
S
R
E
D
V
I
A
---
I
R
D
K
N
N
Q
YFPRLKLAQGRIVRTEIIYDKLTPIIIYDKNIDRNQVKLYVDGAEWINWTRKSMVHAGSTSTIYYMRETIDGNTEFYFGEGEISVNASEGALTANYIGGLKPTQN
S
T
I
V
I
E
Y--
I
S
T
N
G
A
D
A
N
-------------------
G
A
V
-
G
F
S
Y
A
D
T
L
T
-
N
I
T
V
I
N
I
N
E
N
--------
P
NDDPDF
V
G
A
D
G
G
G
D
-
P
E
D
I
E
R
I
R
-------
E
L
--
G
T
I
K
R
E
T
Q
Q
--------
R
C
V
T
-
A
T
D
Y
-
D
T
F
V
S
E
R
-
F
G
S
I
I
Q
A
-------
V
Q
T
F
T
D
S
-----
T
-
K
P
G
Y
A
F
I
-
A
A
K
P
K
-
S
GLYLTTVQ
R
--------
E
D
I
K
N
Y
L
K
---
D
Y
N
L
A
P
I
T
----------------------
P
S
I
--
I
S
P
---
N
Y
L
F
I
K
T
--
N
L
K
V
----------
T
Y
A
L
N
K
LQES
E
Q
--
W
L
-
E
G
Q
-------
I
I
D
K
I
D
R
Y
Y
T
E
DV
E
---------------
I
F
N
S
S
--
F
A
K
S
K
M
L
T
Y
V
--
D
D
A
D
H
S
-
V
I
-
G
S
-------------------------------------------------------------
12
HHSearch
25.90
11%
0
- C- -
-
5IV5
-
BP06_BPT4
X:
[10-478]
------------
L
T
R
T
A
N
A
I
P
E
I
F
--
V
G
G
T
F
-
A
E
I
K
Q
N
L
I
E
W
L
N
G
Q
-
N
----
E
F
L
D
Y--
D
F
E
G
S
R
L
N
V
L
C
D
---
L
L
A
-----
Y
N
T
L
Y
I
Q
Q
F
G
N
A
A
V
Y
E
S
F
M
R
T
A
N
L
R
S
S
V
V
-
Q
A
---------
A
Q
D
N
G
Y
L
P
T
S
K
S
A
A
Q
T
E
I
M
L
T
C
T
DALNR
N
Y
I
---
T
I
P
R
G
T
R
F
L
A
Y
A
KDTSVN
P
Y
-
N
F
--
V
S
R
E
D
V
I
A
---
I
R
D
K
N
N
Q
YFPRLKLAQGRIVRTEIIYDKLTPIIIYDKNIDRNQVKLYVDGAEWINWTRKSMVHAGSTSTIYYMRETIDGNTEFYFGEGEISVNASEGALTANYIGGLKPTQN
S
T
I
V
I
E
Y--
I
S
T
N
G
A
D
A
N
-------------------
G
A
V
-
G
F
S
Y
A
D
T
L
T
-
N
I
T
V
I
N
I
N
E
N
--------
P
NDDPDF
V
G
A
D
G
G
G
D
-
P
E
D
I
E
R
I
R
-------
E
L
--
G
T
I
K
R
E
T
Q
Q
--------
R
C
V
T
-
A
T
D
Y
-
D
T
F
V
S
E
R
-
F
G
S
I
I
Q
A
-------
V
Q
T
F
T
D
S
-----
T
-
K
P
G
Y
A
F
I
-
A
A
K
P
K
-
S
GLYLTTVQ
R
--------
E
D
I
K
N
Y
L
K
---
D
Y
N
L
A
P
I
T
----------------------
P
S
I
--
I
S
P
---
N
Y
L
F
I
K
T
--
N
L
K
V
----------
T
Y
A
L
N
K
LQES
E
Q
--
W
L
-
E
G
Q
-------
I
I
D
K
I
D
R
Y
Y
T
E
DV
E
---------------
I
F
N
S
S
--
F
A
K
S
K
M
L
T
Y
V
--
D
D
A
D
H
S
-
V
I
-
G
S
-------------------------------------------------------------
7
PsiBlast_PDB
23.89
37%
2
- C3 -
-
5L46
1
M2GD_HUMAN
A:
[175-211]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
G
---
A
R
K
C
G
A
-
L
L
-------------------
K
Y
P
-
A
-
P
V
T
S
L
K
A
-
R
S
D
G
T
W
D
V
E
T
--------
P
------
Q
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
9.53
21%
80
- C4 -
-
3GE2
4
?
A:
[42-130]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
V
A
Q
P
T
D
I
D
G
T
Y
--
T
G
Q
D
DG
D
R
I
T
L
V
V
--
T
G
T
T
----------
G
T
W
T
E
L
----
E
S
--
D
G
-
D
Q
K
-------
V
K
Q
V
T
F
D
S
A
N
Q
--
R
M
--------------
I
I
G
D
-------------------
D
V
K
I
Y
-
T
V
N
G
N
Q
I
V
V
D
-
D
M
D
R
D
P
S
D
-
Q
I
V
L
T
K
-------------------------------------