@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT23: (2017-12-11 )
MKIVADENLAFTDYFFSEFGDIQHKAGRTLTHTDVQDAEALLVRSVTAVNESLIQNTALKYVGSATIGTDHLDIQALEKQGITWANAAGCNAQAVAEYVITALLHLDASLLEQQEKFTLGIVGLGNVGKRLAYMAQLLGWKVIGFDPFVQLDSIENVSFQTLLQQANAVSIHVPLTKKGEHATYHLFDEKAFAALQPNTILINSARGPVVKEAALIEDIQCTQRKVVLDVFEHEPVISEGLLNMLALATPHIAGYSLEGKARGTQMIYEAFCQKFGYDINKRFETQLPACEDYFSGHDLKAVLKQKLSQIYDIAQYDANIRACVKEGKVEQKAFDLLRKNYPLRREWAAHGGPQA
Atome Classification :
(20 SA)
.........10........20........30........40........50....-..-...60.--.......70........80........90........100-----------..-------...------.------------..------------------------.110---.....-------------..120.......130.......140....-----.--.--.------150----....-------...160.......170.......180.......190.......200.......210.......220-..-.-.....230....-.-..240...--.-----...250.......260.......270......-.280.......290-.---.---.----..----....300-----........310.......320....-...-.330.......340.......----350...-------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
I
VADENL
A
F
T
D
Y
F
F
S
E
FG
D
I
Q
H
KAG
R
T
L
THT
D
V
Q
D
A
E
A
L
L
V
R
S
V
T
A
V
N
-
E
S
L
I
-
Q
N
-
T
A
L
K
YV--GSATIGTDH
L
D
I
Q
A
L
E
KQGITWANAAGC
N
A
Q
A
V
A
E
Y
V
I
-------------
T
A
-------
L
L
H
------
L
------------
D
A
------------------------
S
L
L
E
---
Q
Q
EK
F
-------------
T
L
G
I
V
GL
G
N
V
G
K
R
L
A
Y
M
A
Q
LLG
W
K
V
IGFD-----P--
F
--
V
------
Q
LD----SIEN-------
V
S
F
Q
T
L
L
QQA
N
A
V
S
I
H
VPLTKKGEH
A
T
Y
H
L
FDEKAFAALQP
N
T
I
L
I
NSARGP
V
V
K
E
A
A
L
I
E
D
I
Q
-C-T
Q
-
R
-
K
V
V
L
D
V
FEHEP
V
-
I
-
S
E
G
L
L
N
M
L
--
A
-----LATPHIA
G
Y
SLEGKAR
G
T
Q
M
I
Y
E
A
F
C
Q
K
FGY
D
-
I
N
K
R
F
ETQLP
A
C
---
E
---
D
---Y----FS----G
H
D
L
K
A
------
V
L
K
Q
K
L
S
Q
I
Y
D
I
A
QYD
A
N
I
-
R
A
C
V
K
-EGK-
V
E
Q
K
A
F
D
L
L
R
KNYPL
R
R
E
W
AA----HGGPQA-------------
60
HHSearch
95.77
42%
-71
- C4 -
-
3OET
1
PDXB_SALTY
E:
[4-359]
M
K
I
L
V
D
E
N
M
P
Y
A
R
E
L
F
S
R
L
G
E
V
K
A
V
P
G
R
P
I
P
V
E
E
L
N
H
A
D
A
L
M
V
R
S
V
T
K
V
N
-
E
S
L
L
-
S
G
-
T
P
I
N
F
V
--
G
T
A
T
A
G
T
D
H
V
D
E
A
W
L
K
Q
A
G
I
G
F
S
A
A
P
G
C
N
A
I
A
V
V
E
Y
V
F
-------------
S
A
-------
L
L
M
------
L
------------
A
E
------------------------
R
D
G
F
---
S
L
R
D
R
-------------
T
I
G
I
V
G
V
G
N
V
G
S
R
L
Q
T
R
L
E
A
L
G
I
R
T
L
L
C
D
-----
P
--
P
--
R
------
A
A
R
GD--
E
G
D
F
-------
R
T
L
D
E
L
V
Q
E
A
D
V
L
T
F
H
T
P
L
Y
K
D
G
P
Y
K
T
L
H
L
A
D
E
T
L
I
R
R
L
K
P
G
A
I
L
I
N
A
C
R
G
P
V
V
D
N
A
A
L
L
A
R
L
N
-
A
G
Q
P
-
L
-
S
V
V
L
D
V
W
E
G
E
P
D
-
L
-
N
V
A
L
L
E
A
V
--
D
-----
I
G
T
S
H
I
A
G
Y
T
L
E
G
K
A
R
G
T
T
Q
V
F
E
A
Y
S
A
F
I
G
R
E
Q
R
-
V
A
L
E
T
L
L
P
A
P
---
E
---
F
G
--
R
I
T
--
L
H
----
G
P
L
D
Q
P
------
T
L
K
R
L
A
H
L
V
Y
D
V
R
R
D
D
A
P
L
-
R
K
V
A
G
------
I
P
G
E
F
D
K
L
R
K
N
Y
L
E
R
R
E
W
S
S
----
L
Y
V
M
C
--------------
61
HHSearch
94.49
42%
-71
- C4 -
-
3OET
1
PDXB_SALTY
H:
[4-359]
M
K
I
L
V
D
E
N
M
P
Y
A
R
E
L
F
S
R
L
G
E
V
K
A
V
P
G
R
P
I
P
V
E
E
L
N
H
A
D
A
L
M
V
R
S
V
T
K
V
N
-
E
S
L
L
-
S
G
-
T
P
I
N
F
V
--
G
T
A
T
A
G
T
D
H
V
D
E
A
W
L
K
Q
A
G
I
G
F
S
A
A
P
G
C
N
A
I
A
V
V
E
Y
V
F
-------------
S
A
-------
L
L
M
------
L
------------
A
E
------------------------
R
D
G
F
---
S
L
R
D
R
-------------
T
I
G
I
V
G
V
G
N
V
G
S
R
L
Q
T
R
L
E
A
L
G
I
R
T
L
L
C
D
-----
P
--
P
--
R
------
A
A
R
GD--
E
G
D
F
-------
R
T
L
D
E
L
V
Q
E
A
D
V
L
T
F
H
T
P
L
Y
K
D
G
P
Y
K
T
L
H
L
A
D
E
T
L
I
R
R
L
K
P
G
A
I
L
I
N
A
C
R
G
P
V
V
D
N
A
A
L
L
A
R
L
N
-
A
G
Q
P
-
L
-
S
V
V
L
D
V
W
E
G
E
P
D
-
L
-
N
V
A
L
L
E
A
V
--
D
-----
I
G
T
S
H
I
A
G
Y
T
L
E
G
K
A
R
G
T
T
Q
V
F
E
A
Y
S
A
F
I
G
R
E
Q
R
-
V
A
L
E
T
L
L
P
A
P
---
E
---
F
G--
R
IT--
L
H
----
G
P
L
D
Q
P
------
T
L
K
R
L
A
H
L
V
Y
D
V
R
R
D
D
A
P
L
-
R
K
V
A
G
------
I
P
G
E
F
D
K
L
R
K
N
Y
L
E
R
R
E
W
S
S
----
L
Y
V
M
C
--------------
63
HHSearch
93.99
40%
-65
- C4 -
-
2O4C
1
PDXB_PSEAE
A:
[1-362]
M
R
I
L
A
D
E
N
I
P
V
V
D
A
F
F
A
D
Q
G
S
I
R
R
L
P
G
R
A
I
D
R
A
A
L
A
E
V
D
V
L
L
V
R
S
V
T
E
V
S
-
R
A
A
L
-
A
G
-
S
P
V
R
F
V
--
G
T
C
T
I
G
T
D
H
L
D
L
D
Y
F
A
E
A
G
I
A
W
S
S
A
P
G
C
N
A
R
G
V
V
D
Y
V
L
-------------
G
C
-------
L
L
A
------
M
------------
A
E
------------------------
V
R
G
A
---
D
L
A
E
R
-------------
T
Y
G
V
V
G
A
G
Q
V
G
G
R
L
V
E
V
L
R
G
L
G
W
K
V
L
V
C
D
-----
P
--
P
--
R
------
Q
A
R
E
P--
D
G
E
F
-------
V
S
L
E
R
L
L
A
E
A
D
V
I
S
L
H
T
P
L
N
R
D
G
E
H
P
T
R
H
L
L
D
E
P
R
L
A
A
L
R
P
G
T
W
L
V
N
A
S
R
G
A
V
V
D
N
Q
A
L
R
R
L
L
E
-
G
G
A
D
-
L
-
E
V
A
L
D
V
W
E
G
E
P
Q
-
A
-
D
P
E
L
A
A
R
C
--
L
-----
I
A
T
P
H
I
A
G
Y
S
L
E
G
K
L
R
G
T
A
Q
I
Y
Q
A
Y
C
A
W
R
G
I
A
-
E
R
V
S
L
Q
D
V
L
P
E
T
---
W
---
L
---
A
G
L
Q
L
N
P
----
G
C
D
P
A
W
------
A
L
A
T
L
C
R
A
V
Y
D
P
R
S
D
D
A
A
F
-
R
R
S
L
T
-
G
D
S
A
T
R
R
A
A
F
D
A
L
R
K
H
Y
P
P
R
R
E
I
T
G
----
L
R
V
A
T
--------------
51
Fugue
93.02
40%
-62
- C4 -
-
2O4C
1
PDXB_PSEAE
A:
[1-380]
M
R
I
L
A
D
E
N
I
P
V
V
D
A
F
F
A
D
Q
G
S
I
R
R
L
P
G
R
A
I
D
R
A
A
L
A
E
V
D
V
L
L
V
R
S
V
T
E
V
S
-
R
A
A
L
-
A
G
-
S
P
V
R
F
V
--
G
T
C
T
I
G
T
D
H
L
D
L
D
Y
F
A
E
A
G
I
A
W
S
S
A
P
G
C
N
A
R
G
V
V
D
Y
V
L
-------------
G
C
-------
L
L
A
------
M
------------
A
E
------------------------
V
R
G
A
---
D
L
A
E
R
-------------
T
Y
G
V
V
G
A
G
Q
V
G
G
R
L
V
E
V
L
R
G
L
G
W
K
V
L
V
C
D
-----
P
--
P
--
R
------
Q
A
R
----
E
P
D
G
E
F
-----
V
S
L
E
R
L
L
A
E
A
D
V
I
S
L
H
T
P
L
N
R
D
G
E
H
P
T
R
H
L
L
D
E
P
R
L
A
A
L
R
P
G
T
W
L
V
N
A
S
R
G
A
V
V
D
N
Q
A
L
R
R
L
L
E
-
G
G
A
D
-
L
-
E
V
A
L
D
V
W
E
G
E
P
Q
-
A
-
D
P
E
L
A
A
R
C
--
L
-----
I
A
T
P
H
I
A
G
Y
S
L
E
G
K
L
R
G
T
A
Q
I
Y
Q
A
Y
C
A
W
R
G
I
A
-
E
R
V
S
L
Q
D
V
L
P
E
T
---
W
---
L
---
A
----
G
L
Q
L
N
P
G
C
D
P
A
W
------
A
L
A
T
L
C
R
A
V
Y
D
P
R
S
D
D
A
A
F
-
R
R
S
L
T
G
D
S
A
-
T
R
R
A
A
F
D
A
L
R
K
H
Y
P
P
R
R
E
I
T
G
L
R
V
A
T
G
G
Q
A
E
L
Q
R
V
V
R
A
L
GAQLV
21
PsiBlast_CBE
91.88
39%
-62
- C4 -
-
2O4C
3
PDXB_PSEAE
B:
[1-354]
M
R
I
L
A
D
E
N
I
P
V
V
D
A
F
F
A
D
Q
G
S
I
R
R
L
P
G
R
A
I
D
R
A
A
L
A
E
V
D
V
L
L
V
R
S
V
T
E
V
S
-
R
A
A
L
-
A
G
-
S
P
V
R
F
V
--
G
T
C
T
I
G
T
D
H
L
D
L
D
Y
F
A
E
A
G
I
A
W
S
S
A
P
G
C
N
A
R
G
V
V
D
Y
V
L
-------------
G
C
-------
L
L
A
------
M
------------
A
E
------------------------
V
R
G
A
---
D
L
A
E
R
-------------
T
Y
G
V
V
G
A
G
Q
V
G
G
R
L
V
E
V
L
R
G
L
G
W
K
V
L
V
C
D
-----
P
--
P
--
R
------
Q
A
R
----
E
P
D
G
EF-----
V
S
L
E
R
L
L
A
E
A
D
V
I
S
L
H
T
P
L
N
R
D
G
E
H
P
T
R
H
L
L
D
E
P
R
L
A
A
L
R
P
G
T
W
L
V
N
A
S
R
G
A
V
V
D
N
Q
A
L
R
R
L
L
E
G
G
-
A
D
-
L
-
E
V
A
L
D
V
W
E
G
E
P
Q
-
A
-
D
P
E
L
A
A
R
C
--
L
-----
I
A
T
P
H
I
A
G
Y
S
L
E
G
K
L
R
G
T
A
Q
I
Y
Q
A
Y
C
A
W
R
G
I
A
-
E
R
V
S
L
Q
D
V
L
P
-----
E
---
T
---
W
----
L
A
----
G
L
Q
L
N
P
GCDPAW
A
L
A
T
L
C
R
A
V
Y
D
P
R
S
D
D
A
A
F
R
R
S
L
T
G
-
D
S
A
-
T
R
R
A
A
F
D
A
L
R
K
H
Y
P
P
R
R
E
--------------------------
3
PsiBlast_PDB
91.80
39%
-66
- C4 -
-
2O4C
1
PDXB_PSEAE
A:
[1-354]
M
R
I
L
A
D
E
N
I
P
V
V
D
A
F
F
A
D
Q
G
S
I
R
R
L
P
G
R
A
I
D
R
A
A
L
A
E
V
D
V
L
L
V
R
S
V
T
E
V
S
-
R
A
A
L
-
A
G
-
S
P
V
R
F
V
--
G
T
C
T
I
G
T
D
H
L
D
L
D
Y
F
A
E
A
G
I
A
W
S
S
A
P
G
C
N
A
R
G
V
V
D
Y
V
L
-------------
G
C
-------
L
L
A
------
M
------------
A
E
------------------------
V
R
G
A
---
D
L
A
E
R
-------------
T
Y
G
V
V
G
A
G
Q
V
G
G
R
L
V
E
V
L
R
G
L
G
W
K
V
L
V
C
D
-----
P
--
P
--
R
------
Q
A
R
----
E
P
D
G
E
F
-----
V
S
L
E
R
L
L
A
E
A
D
V
I
S
L
H
T
P
L
N
R
D
G
E
H
P
T
R
H
L
L
D
E
P
R
L
A
A
L
R
P
G
T
W
L
V
N
A
S
R
G
A
V
V
D
N
Q
A
L
R
R
L
L
E
G
G
-
A
D
-
L
-
E
V
A
L
D
V
W
E
G
E
P
Q
-
A
-
D
P
E
L
A
A
R
C
--
L
-----
I
A
T
P
H
I
A
G
Y
S
L
E
G
K
L
R
G
T
A
Q
I
Y
Q
A
Y
C
A
W
R
G
I
A
-
E
R
V
S
L
Q
D
V
L
P
-----
E
---
T
---
W
----
L
A
----
G
L
Q
L
N
P
GCD
P
A
W
A
L
A
T
L
C
R
A
V
Y
D
P
R
S
D
D
A
A
F
R
R
S
L
T
G
-
D
S
A
-
T
R
R
A
A
F
D
A
L
R
K
H
Y
P
P
R
R
E
--------------------------
2
PsiBlast_PDB
90.31
41%
-65
- C4 -
-
3OET
1
PDXB_SALTY
A:
[5-354]
-
K
I
L
V
D
E
N
M
P
Y
A
R
E
L
F
S
R
L
G
E
V
K
A
V
P
G
---
P
V
E
E
L
N
H
A
D
A
L
M
V
R
S
V
T
K
V
N
-
E
S
L
L
-
S
G
-
T
P
I
N
F
V
--
G
T
A
T
A
G
T
D
H
V
D
E
A
W
L
K
Q
A
G
I
G
F
S
A
A
P
G
C
N
A
I
A
V
V
E
Y
V
F
-------------
S
A
-------
L
L
M
------
L
------------
A
E
------------------------
R
D
G
F
---
S
L
R
D
R
-------------
T
I
G
I
V
G
V
G
N
V
G
S
R
L
Q
T
R
L
E
A
L
G
I
R
T
L
L
C
D
-----
P
P
R
A
--
A
------
R
G
D
----
E
G
D
F
-------
R
T
L
D
E
L
V
Q
E
A
D
V
L
T
F
H
T
P
L
Y
K
D
G
P
Y
K
T
L
H
L
A
D
E
T
L
I
R
R
L
K
P
G
A
I
L
I
N
A
C
R
G
P
V
V
D
N
A
A
L
L
A
R
L
N
-
A
-
G
Q
-
P
L
S
V
V
L
D
V
W
E
G
E
P
D
-
L
-
N
V
A
L
L
E
A
V
--
D
-----
I
G
T
S
H
I
A
G
Y
T
L
E
G
K
A
R
G
T
T
Q
V
F
E
A
Y
S
A
F
I
G
R
E
-
Q
R
V
A
L
E
T
L
L
P
A
P
---
E
FG
R
I
---
T
----
L
H
----
G
P
L
D
Q
P
------
T
L
K
R
L
A
H
L
V
Y
D
V
R
R
D
D
A
P
L
-
R
---
K
-
V
A
G
-
I
P
G
E
-
F
D
K
L
R
K
N
Y
L
E
R
R
E
W
S
S
-----------------------
62
HHSearch
85.85
42%
-43
- C4 -
-
5DT9
1
PDXB_VIBCH
A:
[7-363]
M
K
I
L
I
D
E
N
M
P
Y
A
Q
A
L
F
S
Q
L
G
E
V
I
L
K
P
G
R
T
L
T
A
D
D
L
I
D
V
D
A
L
M
I
R
S
V
T
K
V
N
-
D
A
L
L
-
A
K
A
N
R
L
K
F
V
--
G
T
A
T
A
G
M
D
H
V
D
Q
A
L
L
R
E
R
G
I
F
F
T
A
A
P
G
C
N
K
V
G
V
A
E
Y
V
F
-------------
S
V
-------
L
M
V
------
L
------------
A
Q
------------------------
Q
Q
G
F
---
S
V
F
D
K
-------------
T
V
G
I
I
G
A
G
Q
V
G
S
Y
L
A
K
C
L
S
G
I
G
M
K
V
L
L
N
D
-----
P
--
P
--
K
------
Q
A
Q
GD--
E
R
E
F
-------
T
E
L
E
T
L
L
K
Q
A
D
V
I
T
L
H
T
P
I
T
R
G
G
E
W
P
T
H
H
L
I
D
A
A
I
L
E
Q
L
R
S
D
Q
I
L
I
N
A
A
R
G
P
V
V
D
N
A
A
L
K
A
R
L
Q
-
Q
G
D
G
-
F
-
T
A
V
L
D
V
F
E
F
E
P
Q
-
V
-
D
M
E
L
L
P
L
L
--
A
-----
F
A
T
P
H
I
A
G
Y
G
L
E
G
K
A
R
G
T
T
M
I
F
N
S
Y
C
E
F
L
G
S
A
-
H
C
A
N
P
A
S
L
L
P
K
A
---
P
---
V
P
K
V
Y
----
L
E
----
R
A
W
D
E
E
------
T
L
R
T
L
T
Q
I
I
Y
D
V
R
K
D
D
A
Q
F
-
R
R
E
I
H
------
Q
P
G
A
F
D
L
M
R
K
H
Y
W
D
R
R
E
Y
S
A
----
V
T
L
A
G
--------------
1
PsiBlast_PDB
78.53
42%
-9
- C4 -
-
5DT9
1
PDXB_VIBCH
A:
[7-358]
M
K
I
L
I
D
E
N
M
P
Y
A
Q
A
L
F
S
Q
L
G
E
V
I
L
K
P
G
R
T
L
T
A
D
D
L
I
D
V
D
A
L
M
I
R
S
V
T
K
V
N
-
D
A
L
L
A
K
A
-
N
R
L
K
F
V
--
G
T
A
T
A
G
M
D
H
V
D
Q
A
L
L
R
E
R
G
I
F
F
T
A
A
P
G
C
N
K
V
G
V
A
E
Y
V
F
-------------
S
V
-------
L
M
-----------------------------------------------
V
L
A
---
Q
Q
Q
G
F
SVFD
K
--------
T
V
G
I
I
G
A
G
Q
V
G
S
Y
L
A
K
C
L
S
G
I
G
M
K
V
L
L
N
D
-----
P
--
P
K
Q
A
------
Q
G
D
----
E
R
E
F
-------
T
E
L
E
T
L
L
K
Q
A
D
V
I
T
L
H
T
P
I
T
R
G
G
E
W
P
T
H
H
L
I
D
A
A
I
L
E
Q
L
R
S
D
Q
I
L
I
N
A
A
R
G
P
V
V
D
N
A
A
L
K
A
R
L
Q
-
Q
-
G
D
-
G
F
T
A
V
L
D
V
F
E
F
E
P
Q
-
V
-
D
M
E
L
L
P
L
L
--
A
-----
F
A
T
P
H
I
A
G
Y
G
L
E
G
K
A
R
G
T
T
M
I
F
N
S
Y
C
E
F
L
G
S
A
-
H
C
A
N
P
A
S
L
L
P
K
A
PVP
K
---
V
---
Y
----
L
E
----
R
A
W
D
E
E
------
T
L
R
T
L
T
Q
I
I
Y
D
V
R
K
D
D
A
Q
F
-
R
R
E
I
H
------
Q
P
G
A
F
D
L
M
R
K
H
Y
W
D
R
R
E
Y
S
A
-----------------------
25
PsiBlast_CBE
61.70
31%
-56
- C4 -
-
5TX7
2
?
B:
[66-299]
------------------------------------------------------------
G
L
R
F
V
--
S
V
L
A
T
G
Y
D
K
V
D
V
A
A
A
G
V
L
G
I
P
V
S
N
V
P
G
Y
G
T
D
S
V
A
Q
H
V
F
-------------
A
L
-------
L
L
E
------
L
------------
C
R
R
T
A
L
H
D
H
R
I
R
A
GAWTQSPDWCFWD
S
T
Q
E
---
E
L
T
G
K
-------------
T
M
G
I
V
G
F
G
N
T
G
R
R
V
G
R
I
A
N
A
L
G
M
N
V
I
A
Y
A
-----
P
--
R
--
S
------
R
F
D
PDYR
P
F
E
H
-------
V
G
L
D
E
L
F
T
S
A
D
V
V
S
L
H
C
P
L
T
P
E
T
E
----
G
L
V
D
A
R
R
L
A
S
M
R
P
G
S
Y
L
I
N
T
A
R
G
P
L
L
D
E
R
A
V
A
E
A
L
D
-
S
-
G
R
L
A
-
G
A
G
L
D
V
L
S
Q
E
P
P
-
A
-
A
D
N
P
L
L
S
A
KN
C
-----
L
I
T
P
H
L
A
W
A
S
R
--
T
A
R
R
T
L
M
-------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.21
31%
-54
- C4 -
-
5TX7
2
?
A:
[66-299]
------------------------------------------------------------
G
L
R
F
V
--
S
V
L
A
T
G
Y
D
K
V
D
V
A
A
A
G
V
L
G
I
P
V
S
N
V
P
G
Y
G
T
D
S
V
A
Q
H
V
F
-------------
A
L
-------
L
L
E
------
L
------------
C
R
R
T
A
L
H
D
H
R
I
R
A
GAWTQSPDWCFWD
S
T
Q
E
---
E
L
T
G
K
-------------
T
M
G
I
V
G
F
G
N
T
G
R
R
V
G
R
I
A
N
A
L
G
M
N
V
I
A
Y
A
-----
P
--
R
--
S
------
R
F
D
PDYR
P
F
E
H
-------
V
G
L
D
E
L
F
T
S
A
D
V
V
S
L
H
C
P
L
T
P
E
T
E
----
G
L
V
D
A
R
R
L
A
S
M
R
P
G
S
Y
L
I
N
T
A
R
G
P
L
L
D
E
R
A
V
A
E
A
L
D
-
S
-
G
R
L
A
-
G
A
G
L
D
V
L
S
Q
E
P
P
-
A
-
A
D
N
P
L
L
S
A
KN
C
-----
L
I
T
P
H
L
A
W
A
S
R
--
T
A
R
R
T
L
M
-------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
59.69
28%
-59
- C4 -
-
4LCJ
2
CTBP2_HUMAN
A:
[66-313]
---------------------------------------
A
M
M
Y
H
T
I
T
L
T
R
-
E
D
L
E
-
K
F
-
K
A
L
R
V
I
--
V
R
I
G
S
G
Y
D
N
V
D
I
K
A
A
G
E
L
G
I
A
V
C
N
I
P
S
A
A
V
E
E
T
A
D
S
T
I
-------------
C
H
-------
I
L
N
------
L
Y
R
R
N
T
W
L
Y
Q
A
L
R
E
G
------------------------
T
R
V
Q
---
S
V
E
Q
I
R
E
V
A
SGAARIRG
E
T
L
G
L
I
G
F
G
R
T
G
Q
A
V
A
V
R
A
K
A
F
G
F
S
V
I
F
Y
D
-----
P
--
Y
--
L
------
Q
-
D
----
G
I
E
R
S
L
G
V
Q
R
V
Y
T
L
Q
D
L
L
Y
Q
S
D
C
V
S
L
H
C
N
L
N
---
E
H
-
N
H
H
L
I
N
D
F
T
I
K
Q
M
R
Q
G
A
F
L
V
N
A
A
R
G
G
L
V
D
E
K
A
L
A
Q
A
L
K
-
E
-
G
R
I
R
-
G
A
A
L
D
V
H
E
S
E
P
F
S
F
-
A
Q
G
P
L
K
D
A
--
P
N
L
---
I
C
T
P
H
T
A
W
Y
S
-----------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
58.62
28%
-58
- C4 -
-
2OME
1
CTBP2_HUMAN
A:
[51-298]
---------------------------------------
A
M
M
Y
H
T
I
T
L
T
R
-
E
D
L
E
-
K
F
-
K
A
L
R
V
I
--
V
R
I
G
S
G
Y
D
N
V
D
I
K
A
A
G
E
L
G
I
A
V
C
N
I
P
S
A
A
V
E
E
T
A
D
S
T
I
-------------
C
H
-------
I
L
N
------
L
Y
R
R
N
T
W
L
Y
Q
A
L
R
E
G
------------------------
T
R
V
Q
---
S
V
E
Q
I
R
E
V
A
SGAARIRG
E
T
L
G
L
I
G
F
G
R
T
G
Q
A
V
A
V
R
A
K
A
F
G
F
S
V
I
F
Y
D
-----
P
--
Y
--
L
------
Q
-
D
----
G
I
E
R
S
L
G
V
Q
R
V
Y
T
L
Q
D
L
L
Y
Q
S
D
C
V
S
L
H
C
N
L
N
---
E
H
-
N
H
H
L
I
N
D
F
T
I
K
Q
M
R
Q
G
A
F
L
V
N
A
A
R
G
G
L
V
D
E
K
A
L
A
Q
A
L
K
-
E
-
G
R
I
R
-
G
A
A
L
D
V
H
E
S
E
P
F
S
F
-
A
Q
G
P
L
K
D
A
--
P
N
L
---
I
C
T
P
H
T
A
W
Y
S
-----------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
56.88
33%
-36
- C4 -
-
3DC2
-
SERA_MYCTU
A:
[42-300]
----------------------------------
V
P
E
A
D
A
L
L
V
R
S
A
T
T
V
D
A
E
V
L
A
-
A
A
-
P
K
L
K
I
V
--
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
-------------
A
L
L
L
A
A
S
R
Q
I
P
A
------
A
------------
D
A
------------------------
S
L
R
E
HTW
K
R
S
S
F
S
G
T
E
I
FG
K
-----
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
-----
P
--
Y
--
V
S
P
A
R
A
A
Q
L
-----
G
I
E
L
-------
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
----
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
-
G
-
G
H
V
R
-
A
A
G
L
D
V
F
A
T
E
P
C
-
T
-
D
S
P
L
F
E
L
A
Q-
V
-----
V
V
T
P
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
--------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.80
33%
-31
- C4 -
-
3DDN
1
SERA_MYCTU
A:
[41-299]
----------------------------------
V
P
E
A
D
A
L
L
V
R
S
A
T
T
V
D
A
E
V
L
A
-
A
A
-
P
K
L
K
I
V
--
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
-------------
A
L
L
L
A
A
S
R
Q
I
P
A
------
A
------------
D
A
------------------------
S
L
R
E
HTW
K
R
S
S
F
S
G
T
E
IFG
K
-----
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
-----
P
--
Y
--
V
S
P
A
R
A
A
Q
L
-----
G
I
E
L
-------
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
----
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
-
G
-
G
H
V
R
-
A
A
G
L
D
V
F
A
T
E
P
C
-
T
-
D
S
P
L
F
E
L
A
Q-
V
-----
V
V
T
P
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
--------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
55.29
33%
-32
- C4 -
-
3DDN
1
SERA_MYCTU
B:
[41-301]
----------------------------------
V
P
E
A
D
A
L
L
V
R
S
A
T
T
V
D
A
E
V
L
A
-
A
A
-
P
K
L
K
I
V
--
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
-------------
A
L
L
L
A
A
S
R
Q
I
P
A
------
A
------------
D
A
------------------------
S
L
R
E
HTW
K
R
S
S
F
S
G
T
E
IFG
K
-----
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
-----
P
--
Y
--
V
S
P
A
R
A
A
Q
L
-----
G
I
E
L
-------
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
----
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
-
G
-
G
H
V
R
-
A
A
G
L
D
V
F
A
T
E
P
C
-
T
-
D
S
P
L
F
E
L
A
Q-
V
-----
V
V
T
P
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
--------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
55.25
33%
-36
- C4 -
-
1YGY
-
SERA_MYCTU
A:
[42-300]
----------------------------------
V
P
E
A
D
A
L
L
V
R
S
A
T
T
V
D
A
E
V
L
A
-
A
A
-
P
K
L
K
I
V
--
A
R
A
G
V
G
L
D
N
V
D
V
D
A
A
T
A
R
G
V
L
V
V
N
A
P
T
S
N
I
H
S
A
A
E
H
A
L
-------------
A
L
L
L
A
A
S
R
Q
I
P
A
------
A
------------
D
A
------------------------
S
L
R
E
HTW
K
R
S
S
F
S
G
T
E
IFG
K
-----
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
G
A
Y
V
V
A
Y
D
-----
P
--
Y
--
V
S
P
A
R
A
A
Q
L
-----
G
I
E
L
-------
L
S
L
D
D
L
L
A
R
A
D
F
I
S
V
H
L
P
K
T
P
E
----
T
A
G
L
I
D
K
E
A
L
A
K
T
K
P
G
V
I
I
V
N
A
A
R
G
G
L
V
D
E
A
A
L
A
D
A
I
T
-
G
-
G
H
V
R
-
A
A
G
L
D
V
F
A
T
E
P
C
-
T
-
D
S
P
L
F
E
L
A
Q-
V
-----
V
V
T
P
H
L
G
A
S
T
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
--------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
55.23
31%
-49
- C4 -
-
1PSD
1
SERA_ECOLI
B:
[50-300]
----------------------------------
I
R
D
A
H
F
I
G
L
R
S
R
T
H
L
T
-
E
D
V
I
--
N
-
A
A
E
K
L
V
AI
G
C
F
C
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
GELLLLLRGVPEA
N
A
-------
K
A
H
RGVWNK
L
------------
A
A
------------------------
G
S
F
E
---
A
R
G
K
--------------
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
IENKL
P
--
L
--
G
------
N
A
T
----
Q
V
Q
H
-------
L
S
--
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
----
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
C
D
A
L
A
-
S
-
K
H
L
A
-
G
A
A
I
D
V
F
P
T
E
P
A
-
T
N
S
D
P
F
T
S
P
L
--
C
EFDNV
L
L
T
P
H
I
G
G
S
T
Q
E
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
54.89
31%
-50
- C4 -
-
2P9E
3
SERA_ECOLI
A:
[51-301]
----------------------------------
I
R
D
A
H
F
I
G
L
R
S
R
T
H
L
T
-
E
D
V
I
--
N
-
A
A
E
K
L
V
AI
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
G
E
L
L
L
L
L
R
G
V
P
E
A
N
A
-------
K
A
H
R
G
V
W
N
K
L
------------
A
A
------------------------
G
S
F
E
---
A
R
G
K
--------------
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
I
E
N
K
L
P
--
L
--
G
------
N
A
T
----
Q
V
Q
H
-------
L
S
--
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
----
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
-
S
-
K
H
L
A
-
G
A
A
I
D
V
F
P
T
E
P
A
-
T
N
S
D
P
F
T
S
P
L
--
A
EFDN
V
L
L
T
P
H
I
G
G
S
T
Q
E
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
54.88
31%
-50
- C4 -
-
2P9E
3
SERA_ECOLI
D:
[51-301]
----------------------------------
I
R
D
A
H
F
I
G
L
R
S
R
T
H
L
T
-
E
D
V
I
--
N
-
A
A
E
K
L
V
AI
G
A
F
A
I
G
T
N
Q
V
D
L
D
A
A
A
K
R
G
I
P
V
F
N
A
P
F
S
N
T
R
S
V
A
E
L
V
I
GELLLLLRGVPEA
N
A
-------
K
A
H
RGVWNK
L
------------
A
A
------------------------
G
S
F
E
---
A
R
G
K
--------------
K
L
G
I
I
G
Y
G
H
I
G
T
Q
L
G
I
L
A
E
S
L
G
M
Y
V
Y
F
Y
D
IENKL
P
--
L
--
G
------
N
A
T
----
Q
V
Q
H
-------
L
S
--
D
L
L
N
M
S
D
V
V
S
L
H
V
P
E
N
P
----
S
T
K
N
M
M
G
A
K
E
I
S
L
M
K
P
G
S
L
L
I
N
A
S
R
G
T
V
V
D
I
P
A
L
A
D
A
L
A
-
S
-
K
H
L
A
-
G
A
A
I
D
V
F
P
T
E
P
A
-
T
N
S
D
P
F
T
S
P
L
--
A
EFDNV
L
L
T
P
H
I
G
G
S
T
Q
E
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------