@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VT58: (2017-12-11 )
MQPKFNLPRHCVMSKVVLEAKDIYKHFDDGKSKVEVIKGLSLQVEAGQFVSIVGASGSGKSTLLHVLGGLDQPTKGQVFLNGQRFDNLGEAERGFQRNQYLGFVYQFHHLLPEFTALENVAMPLMLRADNQYKSVKAQAEYLLDRVGLSHRMDHKPGELSGGERQRVALARALVTKPAVVLADEPTGNLDRKTAVGIFELLTDLKKELNMAMLIVTHDEQLAQAADSILHMEDGLWVNGS
Atome Classification :
(57 SA)
.........10........20........30........40........50........60........70........80........90.....---.-..100----.......-..110.......120.--....--...130.-.-..-...140..--.....150-...-..--..160.......170.......180.......190.......200.......210......-.220-.-.-.....230.......240-----------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MQPKFNL
P
R
H
C
V
M
S
K
V
V
L
E
A
K
D
I
Y
K
H
FDDGK
S
K
V
E
VIKG
L
S
L
Q
V
EA
G
Q
F
V
S
I
V
GASGS
G
K
S
T
L
L
H
V
LGGLDQPTKG
Q
V
F
LNGQRFDNL
G
E
A
E
RGFQ---R-N
Q
Y
------
L
G
F
V
Y
Q
F
-
H
H
LL
P
E
F
T
A
L
E
N
V-A
M
--
P
L
M
L--RADN
Q
Y
K
-
S
-
V
K
-
A
Q
A
E
Y
L
L
D
--
R
VGLSHRM-DHK-PG--ELSGG
E
R
Q
R
V
A
L
A
R
A
L
VTK
P
A
V
V
L
A
DEPTGNLD
R
K
T
A
V
G
I
F
E
L
L
T
D
L
K
K
EL
N
M
A
M
L
I
V
TH
D
-
E
Q
L
A
-
Q
-
A
-
A
D
S
I
L
HMED
G
L
W
VNGS-------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
90.69
50%
-110
- C1 -
-
2PCL
5
LOLD_AQUAE
A:
[18-218]
----------------------------------
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
---
R
-
N
R
K
------
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
--
P
-
M
L
--
K
M
G
K
P
K
K
-
E
-
A
K
-
E
R
G
E
Y
L
L
S
--
E
L
G
L
G
D
K
L
-
S
R
K
-
P
Y
--
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
E
G
G
T
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
-
L
-
T
H
R
T
L
E
M
K
D
G
K
V
V
----------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.96
50%
-113
- C1 -
-
2PCJ
-
LOLD_AQUAE
A:
[18-218]
----------------------------------
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
Y
T
N
E
K
E
L
S
L
L
---
R
-
N
R
K
------
L
G
F
V
F
Q
F
-
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
--
P
-
M
L
--
K
M
G
K
P
K
K
-
E
-
A
K
-
E
R
G
E
Y
L
L
S
--
E
L
G
L
G
D
K
L
-
S
R
K
-
P
Y
--
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
E
G
G
T
S
I
V
M
V
T
H
E
-
R
E
L
A
-
E
-
L
-
T
H
R
T
L
E
M
K
D
G
K
V
V
----------------------------------------------------------------------------------------------------------------------------------
169
Fugue
88.41
36%
-122
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
--
D
N
T
P
K
-
D
-
E
-
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
TVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-----------
156
HHSearch
84.92
37%
-134
- C1 -
-
3DHW
-
METN_ECOLI
C:
[1-221]
----------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
-
T
K
---
A
-
R
R
Q
------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
--
D
N
T
-
P
K
D
-
E
-
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
V
-
K
R
I
-
C
D
C
V
A
V
I
S
N
G
E
L
I
E
---------------------------------------------------------------------------------------------------------------------------------
157
HHSearch
84.54
36%
-126
- C1 -
-
3TUI
1
METN_ECOLI
C:
[23-244]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
-
T
K
---
A
-
R
R
Q
------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
--
D
N
T
-
P
K
D
-
E
-
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
V
-
K
R
I
-
C
D
C
V
A
V
I
S
N
G
E
L
I
E
---------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
78.61
39%
-30
- C1 -
-
1L2T
3
Y796_METJA
A:
[1-221]
----------------
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
---
R
-
R
D
K
------
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
G
A
M
S
G
E
-
E
-
R
R
-
K
R
A
L
E
C
L
K
--
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
-------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
78.08
42%
0
- C- -
-
5NIL
-
?
J:
[4-238]
----------------
L
L
E
L
K
D
I
R
R
S
Y
P
A
G
D
E
Q
V
E
V
L
K
G
I
S
L
D
I
Y
A
G
E
M
V
A
I
V
G
A
S
G
S
G
K
S
T
L
M
N
I
L
G
C
L
D
K
A
T
S
G
T
Y
R
V
A
G
Q
D
V
A
T
L
D
A
D
A
L
A
Q
L
---
R
-
R
E
H
------
F
G
F
I
F
Q
R
-
Y
H
L
L
S
H
L
T
A
E
Q
N
V
-
E
V
--
P
-
A
V
--
Y
A
G
L
E
R
K
-
Q
-
R
L
-
L
R
A
Q
E
L
L
Q
--
R
L
G
L
E
D
R
T
-
E
Y
Y
-
P
A
--
Q
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
M
N
G
G
Q
V
I
L
A
D
E
P
T
G
A
L
D
S
H
S
G
E
E
V
M
A
I
L
H
Q
L
R
D
R
-
G
H
T
V
I
I
V
T
H
D
-
P
Q
V
A
-
A
-
Q
-
A
E
R
V
I
E
I
R
D
G
-------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
78.08
42%
0
- C- -
-
5NIK
-
?
J:
[4-238]
----------------
L
L
E
L
K
D
I
R
R
S
Y
P
A
G
D
E
Q
V
E
V
L
K
G
I
S
L
D
I
Y
A
G
E
M
V
A
I
V
G
A
S
G
S
G
K
S
T
L
M
N
I
L
G
C
L
D
K
A
T
S
G
T
Y
R
V
A
G
Q
D
V
A
T
L
D
A
D
A
L
A
Q
L
---
R
-
R
E
H
------
F
G
F
I
F
Q
R
-
Y
H
L
L
S
H
L
T
A
E
Q
N
V
-
E
V
--
P
-
A
V
--
Y
A
G
L
E
R
K
-
Q
-
R
L
-
L
R
A
Q
E
L
L
Q
--
R
L
G
L
E
D
R
T
-
E
Y
Y
-
P
A
--
Q
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
M
N
G
G
Q
V
I
L
A
D
E
P
T
G
A
L
D
S
H
S
G
E
E
V
M
A
I
L
H
Q
L
R
D
R
-
G
H
T
V
I
I
V
T
H
D
-
P
Q
V
A
-
A
-
Q
-
A
E
R
V
I
E
I
R
D
G
-------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.89
40%
-18
- C1 -
-
1F3O
1
Y796_METJA
A:
[2-221]
-----------------
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
---
R
-
R
D
K
------
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
K
Y
R
G
A
M
S
G
E
-
E
-
R
R
-
K
R
A
L
E
C
L
K
--
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
-------------------------------------------------------------------------------------------------------------------------------------
173
Fugue
76.65
32%
-103
- C1 -
-
1Z47
-
?
A:
[11-355]
-------------
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
---
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
T
D
L
P
P
Q
K
R
N
----------------
V
G
L
V
F
Q
N
-
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
--
G
L
R
E
--
K
-
R
V
P
K
D
-
E
-
M
D
-
A
R
V
R
E
L
L
R
--
F
M
R
L
E
S
Y
A
-
N
R
F
-
P
H
--
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
-
Q
E
E
A
-
L
-
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
EKPGT
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
NG
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
8
PsiBlast_PDB
76.60
39%
-58
- C1 -
-
3DHW
-
METN_ECOLI
C:
[1-217]
----------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
D
E
-
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
76.56
39%
-35
- C1 -
-
1L2T
3
Y796_METJA
B:
[1-221]
----------------
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
---
R
-
R
D
K
------
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
G
A
M
S
G
E
-
E
-
R
R
-
K
R
A
L
E
C
L
K
--
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
-------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
76.17
38%
-37
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-221]
----------------
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
---
R
-
R
D
K
------
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
G
A
M
S
G
E
-
E
-
R
R
-
K
R
A
L
E
C
L
K
--
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
-------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
76.12
38%
-66
- C1 -
-
3TUZ
1
METN_ECOLI
C:
[23-240]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
-
D
E
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
76.11
38%
-36
- C1 -
-
3TIF
4
Y796_METJA
A:
[1-221]
----------------
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
L
D
D
D
E
L
T
K
I
---
R
-
R
D
K
------
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
G
A
M
S
G
E
-
E
-
R
R
-
K
R
A
L
E
C
L
K
--
M
A
E
L
E
E
R
F
A
N
H
K
-
P
N
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
-------------------------------------------------------------------------------------------------------------------------------------
150
HHSearch
76.01
35%
-128
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[3-214]
----------------
S
V
Q
L
Q
N
V
T
K
A
W
G
E
----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
M
N
D
T
P
------
P
---
A
-
E
R
G
------
V
G
M
V
F
Q
S
-
Y
A
L
Y
P
H
L
S
V
A
E
N
M
-
S
F
--
G
L
K
L
--
A
G
A
-
K
K
E
-
V
-
I
N
-
Q
R
V
N
Q
V
A
E
--
V
L
Q
L
A
H
L
L
-
D
R
K
-
P
K
--
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
-
Q
V
E
A
-
M
T
L
-
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
---------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
75.45
38%
-66
- C1 -
-
3TUI
1
METN_ECOLI
H:
[23-240]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
-
D
E
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
74.99
38%
-66
- C1 -
-
3TUI
1
METN_ECOLI
C:
[23-240]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
-
D
E
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
74.53
38%
-66
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-240]
---------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
-
D
E
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
74.42
38%
-57
- C1 -
-
3TUZ
1
METN_ECOLI
G:
[24-240]
----------------
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
K
A
---
R
-
R
Q
-------
I
G
M
I
F
Q
H
-
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
----
D
N
T
P
K
-
D
E
V
K
-
R
R
V
T
E
L
L
S
--
L
V
G
L
G
D
K
H
-
D
S
Y
-
P
S
--
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
69.18
40%
-62
- C1 -
-
4YMV
1
?
A:
[6-215]
---------------------
D
V
Y
K
N
F
----
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
---
R
--
Q
K
------
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A-
P
V
K
V
--
K
K
M
N
K
-
K
-
E
-
A
E
-
E
L
A
V
D
L
L
A
--
K
V
G
L
L
D
K
K
-
D
Q
Y
-
P
I
--
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
----------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
68.91
40%
-64
- C1 -
-
4YMV
1
?
J:
[6-215]
---------------------
D
V
Y
K
N
F
----
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
---
R
--
Q
K
------
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A-
P
V
K
V
--
K
K
M
N
K
-
K
-
E
-
A
E
-
E
L
A
V
D
L
L
A
--
K
V
G
L
L
D
K
K
-
D
Q
Y
-
P
I
--
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
----------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
68.22
40%
-62
- C1 -
-
4YMU
1
?
A:
[6-215]
---------------------
D
V
Y
K
N
F
----
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
---
R
--
Q
K
------
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A-
P
V
K
V
--
K
K
M
N
K
-
K
-
E
-
A
E
-
E
L
A
V
D
L
L
A
--
K
V
G
L
L
D
K
K
-
D
Q
Y
-
P
I
--
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
----------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
67.82
40%
-55
- C1 -
-
4YMU
1
?
J:
[6-215]
---------------------
D
V
Y
K
N
F
----
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
K
V
---
R
--
Q
K
------
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A-
P
V
K
V
--
K
K
M
N
K
-
K
-
E
-
A
E
-
E
L
A
V
D
L
L
A
--
K
V
G
L
L
D
K
K
-
D
Q
Y
-
P
I
--
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
----------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
66.11
35%
-65
* C1 *
-
4U00
1
?
A:
[4-214]
----------------
I
I
R
I
R
N
L
H
K
W
F
----
G
P
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
K
D
-
D
R
A
L
R
E
I
R
---
R
-
E
--------
V
G
M
V
F
Q
Q
-
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
-
P
M
R
V
--
R
R
W
P
R
E
K
-
A
-
E
K
-
K
A
L
E
-
L
L
E
--
R
V
G
I
L
D
Q
A
-
R
K
Y
-
P
A
--
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
A
D
R
V
V
F
M
D
G
G
-------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
59.41
35%
-35
- C1 -
-
3C41
2
?
K:
[16-217]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
101
PsiBlast_CBE
57.24
34%
-10
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-221]
---------------
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
----
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
K
D
G
Q
L
K
VAD
K
-
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
-
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
--
P
I
Q
V
--
L
G
L
S
K
H
D
-
A
-
R
E
-
R
A
L
K
Y
L
A
---
K
V
G
I
D
E
R
A
-
Q
G
K
Y
P
V
--
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
-
G
K
T
M
V
V
V
T
H
E
-
M
G
F
A
-
R
-
H
-
V
S
S
--------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
57.22
35%
-31
- C1 -
-
3C4J
2
?
A:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
57.06
35%
-28
- C1 -
-
3C4J
2
?
B:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
56.86
35%
-32
- C1 -
-
2Q0H
3
?
B:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
56.68
35%
-32
- C1 -
-
2OLK
1
?
A:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
56.65
35%
-27
- C1 -
-
2Q0H
3
?
A:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
80
PsiBlast_CBE
56.61
35%
-33
- C1 -
-
2OLK
1
?
C:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
56.01
35%
-29
- C1 -
-
2OLJ
3
?
A:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
55.25
35%
-30
- C1 -
-
3C41
2
?
J:
[16-217]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
54.90
35%
-30
- C1 -
-
2OLK
1
?
D:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
54.67
35%
-31
- C1 -
-
2OLK
2
?
B:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
53.79
35%
-25
- C1 -
-
2OLJ
2
?
B:
[37-238]
---------------------------------
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
---
N
L
K
A
K
D
T
N
L
N
---
K
V
R
E
E
------
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A-
P
M
K
V
--
R
K
W
P
R
E
K
-
A
--
E
-
A
K
A
M
E
L
L
D
--
K
V
G
L
K
D
K
A
-
H
A
Y
-
P
D
--
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
L
F
M
D
G
G
Y
I
I
----------------------------------------------------------------------------------------------------------------------------------
122
PsiBlast_CBE
48.97
32%
-63
- C1 -
-
4HLU
1
ECFA1_THEMA
D:
[26-215]
-----------------------------------
V
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
D
G
S
P
A
D
P
-------
F
L
---
L
-
R
K
N
------
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
G
A
T
V
E
E
D
V
-
A
F
--
S
L
E
I
--
M
G
L
D
E
-
S
-
E
-
M
R
-
K
R
I
K
K
V
L
E
--
L
V
G
L
S
G
L
A
-
A
A
D
-
P
L
--
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
V
L
E
S
L
K
N
E
-
G
K
G
I
I
L
V
T
H
E
-
L
E
Y
L
-
D
-
D
-
M
D
F
I
L
H
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
123
PsiBlast_CBE
48.70
32%
-62
- C1 -
-
4HLU
1
ECFA1_THEMA
C:
[26-215]
-----------------------------------
V
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
D
G
S
P
A
D
P
-------
F
L
---
L
-
R
K
N
------
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
G
A
T
V
E
E
D
V
-
A
F
--
S
L
E
I
--
M
G
L
D
E
-
S
-
E
-
M
R
-
K
R
I
K
K
V
L
E
--
L
V
G
L
S
G
L
A
-
A
A
D
-
P
L
--
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
V
L
E
S
L
K
N
E
-
G
K
G
I
I
L
V
T
H
E
-
L
E
Y
L
-
D
-
D
-
M
D
F
I
L
H
I
S
N
G
-------------------------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
48.13
33%
-24
- C1 -
-
5L22
2
?
B:
[345-543]
--------------------------------
K
T
P
V
L
R
N
I
N
M
R
I
L
P
G
E
F
V
A
I
I
G
P
S
G
S
G
K
S
S
L
V
R
T
I
L
G
I
W
L
P
V
H
G
T
V
E
I
D
G
A
---
D
L
K
Q
W
D
R
D
Y
----
F
-
G
K
F
------
V
G
Y
L
P
Q
D
-
I
E
L
F
-
E
G
T
V
A
E
N
I
-
A
R
--
F
G
E
L
--
D
S
E
K
I
I
E
-
A
-
A
K
L
S
G
A
H
D
V
I
I
--
K
L
P
D
G
Y
D
T
-
Y
I
G
-
P
G
GI
T
L
S
G
G
Q
R
Q
R
I
A
L
A
R
A
L
Y
G
N
P
R
I
V
I
L
D
E
P
D
S
N
L
D
E
Q
G
E
Q
A
L
Y
N
A
L
I
E
L
K
K
R
-
K
V
T
T
I
I
V
S
H
R
-
I
R
L
L
-
N
-
L
-
V
D
K
I
A
I
M
Q
D
G
-------------------------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
48.10
33%
-24
- C1 -
-
5L22
2
?
A:
[345-543]
--------------------------------
K
T
P
V
L
R
N
I
N
M
R
I
L
P
G
E
F
V
A
I
I
G
P
S
G
S
G
K
S
S
L
V
R
T
I
L
G
I
W
L
P
V
H
G
T
V
E
I
D
G
A
---
D
L
K
Q
W
D
R
D
Y
----
F
-
G
K
F
------
V
G
Y
L
P
Q
D
-
I
E
L
F
-
E
G
T
V
A
E
N
I
-
A
R
--
F
G
E
L
--
D
S
E
K
I
I
E
-
A
-
A
K
L
S
G
A
H
D
V
I
I
--
K
L
P
D
G
Y
D
T
-
Y
I
G
-
P
G
GI
T
L
S
G
G
Q
R
Q
R
I
A
L
A
R
A
L
Y
G
N
P
R
I
V
I
L
D
E
P
D
S
N
L
D
E
Q
G
E
Q
A
L
Y
N
A
L
I
E
L
K
K
R
-
K
V
T
T
I
I
V
S
H
R
-
I
R
L
L
-
N
-
L
-
V
D
K
I
A
I
M
Q
D
G
-------------------------------------------------------------------------------------------------------------------------------------
147
PsiBlast_CBE
42.39
31%
-35
- C1 -
-
1XEF
2
HLYBP_ECOLX
C:
[18-213]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
138
PsiBlast_CBE
41.25
31%
-35
- C1 -
-
2FGK
2
HLYBP_ECOLX
B:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
142
PsiBlast_CBE
41.17
31%
-34
- C1 -
-
2FGJ
2
HLYBP_ECOLX
C:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
139
PsiBlast_CBE
40.97
31%
-35
- C1 -
-
2FGK
2
HLYBP_ECOLX
A:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
141
PsiBlast_CBE
40.70
31%
-30
- C1 -
-
2FGJ
2
D:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
146
PsiBlast_CBE
40.58
31%
-29
- C1 -
-
1XEF
2
D:
[18-213]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
135
PsiBlast_CBE
40.58
31%
-43
- C1 -
-
3B5J
1
A:
[20-215]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
145
PsiBlast_CBE
40.52
31%
-40
- C1 -
-
2FFA
2
A:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
136
PsiBlast_CBE
40.31
31%
-37
- C1 -
-
2FGK
2
D:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
130
PsiBlast_CBE
40.27
31%
-43
- C1 -
-
2PMK
1
A:
[20-215]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
131
PsiBlast_CBE
40.23
31%
-40
- C1 -
-
2FF7
1
A:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
143
PsiBlast_CBE
40.05
31%
-28
- C1 -
-
2FGJ
2
HLYBP_ECOLX
B:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
144
PsiBlast_CBE
39.92
31%
-30
- C1 -
-
2FGJ
2
HLYBP_ECOLX
A:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
E
L
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
148
PsiBlast_CBE
39.46
31%
-29
- C1 -
-
1XEF
2
HLYBP_ECOLX
B:
[18-213]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------
137
PsiBlast_CBE
39.24
31%
-34
- C1 -
-
2FGK
2
HLYBP_ECOLX
C:
[24-219]
-----------------------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
---
D
L
A
L
A
D
P
N
W
L
---
R
-
R
Q
-------
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
AN
P
G
M
S
--
V
E
K
V
I
Y
A
-
A
-
K
L
-
A
G
A
H
D
F
I
S
EL
R
E
G
Y
N
T
I
V
-
G
E
Q
-
G
A
--
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
K
--
G
R
T
V
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
-------------------------------------------------------------------------------------------------------------------------------------