@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTE3: (2017-12-13 )
MPQDQHLGVDKAKILIEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLNPIVVHGGGPQVDSFLKQLGRESDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINKHGGRAIGLTGQDGNLLRARKLLMEKQEEDGSIKHIDLGMVGEVTGVKTDVLEMFTQSDFIPVIAPLGVDEKGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLTTQEVDRLIETGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLISNRTQTTH
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130..-.....140-.......150.---------......160.......170.......180.......190.......200.......210.......220..-..--.----..230.......240.......250.......260.......270.......280.......290.......300
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MPQDQHLG
V
D
K
A
K
I
L
I
E
A
L
P
Y
I
Q
R
FSG
K
T
L
V
V
K
YGGNAMTD
P
E
L
E
S
S
F
AR
D
I
V
L
L
K
TVGL
N
P
I
V
V
HGGGP
Q
V
D
S
F
L
K
Q
LGRESDRID
G
M
RVT
D
E
A
T
M
E
V
V
E
M
V
LGGSV
N
K
S
I
V
N
L
I
N
KHG
G
R
A
I
G
LTGQDG
N
L
L
-
R
A
R
K
L
L
M
E
-KQEEDG
S
I
K
H
I
---------DLGMVGEVTGV
K
T
D
V
L
E
M
F
T
QSDF
I
P
V
IAPLGVDEKG
N
T
Y
NI
N
A
D
L
V
A
G
K
V
A
E
A
LGA
E
K
L
I
L
L
TNI
S
G
V
LD-EN--K----NLLTGL
T
T
Q
E
V
D
R
L
I
E
T
G
V
IYGGMIPKV
G
C
A
L
D
A
VKG
G
V
V
S
A
H
IVDGRV
P
H
A
T
L
L
E
I
F
TDHG
V
G
T
L
ISNRTQTTH
38
PsiBlast_CBE
91.49
49%
-128
- C1 -
-
2BTY
2
ARGB_THEMA
C:
[3-278]
--------
I
D
T
V
N
V
L
L
E
A
L
P
Y
I
K
E
F
Y
G
K
T
F
V
I
K
F
G
G
S
A
M
K
Q
E
N
A
K
K
A
F
I
Q
D
I
I
L
L
K
Y
T
G
I
K
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
-
V
A
E
K
-----------
E
T
K
H
G
---------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
L
K
-
D
G
--
K
-----
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
I
N
G
G
L
E
H
A
I
L
L
E
I
F
S
R
K
G
I
G
T
M
I
K
-------
67
HHSearch
90.51
51%
-125
- C1 -
-
2BTY
2
ARGB_THEMA
B:
[3-281]
--------
I
D
T
V
N
V
L
L
E
A
L
P
Y
I
K
E
F
Y
G
K
T
F
V
I
K
F
G
G
S
A
M
K
Q
E
N
A
K
K
A
F
I
Q
D
I
I
L
L
K
Y
T
G
I
K
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
-
V
A
E
K
E
-----------
T
K
H
G
---------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
L
K
-
D
---
G
----
K
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
I
N
G
G
L
E
H
A
I
L
L
E
I
F
S
R
K
G
I
G
T
M
I
K
E
L
E
----
65
HHSearch
90.14
65%
-83
- C1 -
-
2BUF
-
ARGB_PSEAE
C:
[4-298]
----
R
D
D
A
A
Q
V
A
K
V
L
S
E
A
L
P
Y
I
R
R
F
V
G
K
T
L
V
I
K
Y
G
G
N
A
M
E
S
E
E
L
K
A
G
F
A
R
D
V
V
L
M
K
A
V
G
I
N
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
-
R
A
K
K
L
T
V
T
R
Q
T
P
E
M
T
K
P
E
I
I
---------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
M
D
-
K
Q
--
G
----
Q
V
L
T
G
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
G
R
V
P
N
A
V
L
L
E
I
F
T
D
S
G
V
G
T
L
I
S
N
R
K
----
1
PsiBlast_PDB
89.87
66%
-78
- C1 -
-
2BUF
-
ARGB_PSEAE
A:
[11-299]
-----------
A
K
V
L
S
E
A
L
P
Y
I
R
R
F
V
G
K
T
L
V
I
K
Y
G
G
N
A
M
E
S
E
E
L
K
A
G
F
A
R
D
V
V
L
M
K
A
V
G
I
N
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
-
R
A
K
K
L
T
V
T
-
R
Q
--------
I
I--------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
M
D
-
K
Q
--
G
----
Q
V
L
T
G
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
G
R
V
P
N
A
V
L
L
E
I
F
T
D
S
G
V
G
T
L
I
S
N
R
K
R
---
39
PsiBlast_CBE
89.84
49%
-126
- C1 -
-
2BTY
2
ARGB_THEMA
B:
[3-278]
--------
I
D
T
V
N
V
L
L
E
A
L
P
Y
I
K
E
F
Y
G
K
T
F
V
I
K
F
G
G
S
A
M
K
Q
E
N
A
K
K
A
F
I
Q
D
I
I
L
L
K
Y
T
G
I
K
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
-
V
A
E
K
-----------
E
T
K
H
G
---------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
L
K
-
D
G
--
K
-----
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
I
N
G
G
L
E
H
A
I
L
L
E
I
F
S
R
K
G
I
G
T
M
I
K
-------
21
PsiBlast_CBE
88.73
66%
-75
- C1 -
-
2BUF
20
ARGB_PSEAE
L:
[11-298]
-----------
A
K
V
L
S
E
A
L
P
Y
I
R
R
F
V
G
K
T
L
V
I
K
Y
G
G
N
A
M
E
S
E
E
L
K
A
G
F
A
R
D
V
V
L
M
K
A
V
G
I
N
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
-
R
A
K
K
L
T
V
T
-
R
Q
-----
K
P
E
I
I--------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
M
D
-
K
Q
--
G
----
Q
V
L
T
G
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
G
R
V
P
N
A
V
L
L
E
I
F
T
D
S
G
V
G
T
L
I
S
N
R
K
----
4
PsiBlast_PDB
88.14
49%
-126
- C1 -
-
2BTY
2
ARGB_THEMA
A:
[3-278]
--------
I
D
T
V
N
V
L
L
E
A
L
P
Y
I
K
E
F
Y
G
K
T
F
V
I
K
F
G
G
S
A
M
K
Q
E
N
A
K
K
A
F
I
Q
D
I
I
L
L
K
Y
T
G
I
K
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
-
V
A
E
K
-----------
E
T
K
H
G
---------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
L
K
-
D
G
--
K
-----
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
I
N
G
G
L
E
H
A
I
L
L
E
I
F
S
R
K
G
I
G
T
M
I
K
-------
68
HHSearch
86.39
51%
-85
- C1 -
-
2RD5
3
NAGK_ARATH
B:
[16-297]
------
S
P
D
Y
R
V
E
I
L
S
E
S
L
P
F
I
Q
K
F
R
G
K
T
I
V
V
K
Y
G
G
A
A
M
T
S
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
V
G
L
R
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
-
T
A
R
P
V
P
-----------
N
S
A
---------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
L
E
N
K
E
DP
S
----
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
G
R
R
Q
H
S
L
L
H
E
I
M
S
D
E
G
A
G
T
M
I
T
-------
5
PsiBlast_PDB
85.72
51%
-100
- C1 -
-
2RD5
3
NAGK_ARATH
A:
[20-297]
----------
R
V
E
I
L
S
E
S
L
P
F
I
Q
K
F
R
G
K
T
I
V
V
K
Y
G
G
A
A
M
T
S
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
V
G
L
R
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
-
T
A
R
P
V
P
N
S
-
A
Q
-------------------
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
L
--
E
N
--
K
EDPS
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
G
R
R
Q
H
S
L
L
H
E
I
M
S
D
E
G
A
G
T
M
I
T
-------
40
PsiBlast_CBE
85.65
51%
-98
- C1 -
-
2RD5
3
NAGK_ARATH
B:
[20-297]
----------
R
V
E
I
L
S
E
S
L
P
F
I
Q
K
F
R
G
K
T
I
V
V
K
Y
G
G
A
A
M
T
S
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
V
G
L
R
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
-
T
A
R
P
V
P
N
S
-
A
Q
-------------------
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
L
--
E
N
--
K
EDPS
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
G
R
R
Q
H
S
L
L
H
E
I
M
S
D
E
G
A
G
T
M
I
T
-------
70
HHSearch
85.54
52%
-80
- C1 -
-
2V5H
2
ARGB_SYNE7
E:
[30-312]
-------
A
A
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
P
H
D
------------
Q
E
---------
G
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
V
G
S
G
----
41
PsiBlast_CBE
85.11
51%
-106
- C1 -
-
4USJ
2
NAGK_ARATH
B:
[40-317]
----------
R
V
E
I
L
S
E
S
L
P
F
I
Q
K
F
R
G
K
T
I
V
V
K
Y
G
G
A
A
M
T
S
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
V
G
L
R
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
-
T
A
R
P
V
P
N
S
-
A
Q
-------------------
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
L
--
E
N
--
K
EDPS
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
G
R
R
Q
H
S
L
L
H
E
I
M
S
D
E
G
A
G
T
M
I
T
-------
6
PsiBlast_PDB
84.00
51%
-96
- C1 -
-
4USJ
3
NAGK_ARATH
A:
[40-317]
----------
R
V
E
I
L
S
E
S
L
P
F
I
Q
K
F
R
G
K
T
I
V
V
K
Y
G
G
A
A
M
T
S
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
V
G
L
R
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
-
T
A
R
P
V
P
N
S
-
A
Q
-------------------
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
L
--
E
N
--
K
EDPS
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
G
R
R
Q
H
S
L
L
H
E
I
M
S
D
E
G
A
G
T
M
I
T
-------
33
PsiBlast_CBE
83.86
50%
-82
- C1 -
-
2V5H
2
ARGB_SYNE7
E:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
69
HHSearch
83.68
52%
-79
* C1 *
-
2V5H
1
ARGB_SYNE7
B:
[30-312]
-------
A
A
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
P
H
D
------------
Q
E
---------
G
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
V
G
S
G
----
32
PsiBlast_CBE
83.68
50%
-82
- C1 -
-
2V5H
1
ARGB_SYNE7
F:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
34
PsiBlast_CBE
83.51
50%
-82
- C1 -
-
2V5H
2
ARGB_SYNE7
D:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
37
PsiBlast_CBE
83.10
50%
-89
- C1 -
-
2JJ4
1
ARGB_SYNE7
B:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
36
PsiBlast_CBE
82.83
50%
-82
- C1 -
-
2V5H
1
ARGB_SYNE7
B:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
2
PsiBlast_PDB
82.51
50%
-88
- C1 -
-
2JJ4
1
ARGB_SYNE7
A:
[32-308]
---------
D
R
V
R
I
L
S
E
A
L
P
Y
L
Q
Q
F
A
G
R
T
V
V
V
K
Y
G
G
A
A
M
K
Q
E
E
L
K
E
A
V
M
R
D
I
V
F
L
A
C
V
G
M
R
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
-
L
A
R
------
P
H
D
Q
E
G
---------------
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
L
E
-
D
P
--
K
RPE-
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
G
R
I
P
H
A
L
L
L
E
I
F
T
D
A
G
I
G
T
M
I
--------
84
HHSearch
69.56
31%
-132
- C1 -
-
3L86
2
ARGB_STRMU
A:
[35-270]
-------------------------
M
K
D
I
I
V
I
K
I
G
G
V
A
S
Q
Q
L
--
S
G
D
F
L
S
Q
I
K
N
W
Q
D
A
G
K
Q
L
V
I
V
H
G
G
G
F
A
I
N
K
L
M
E
E
N
Q
V
P
V
K
K
I
N
G
L
R
V
T
S
K
D
D
M
V
L
V
S
H
A
L
L
D
L
V
G
K
N
L
Q
E
K
L
R
Q
A
G
V
S
C
Q
Q
L
K
S
D
I
K
H
V
V
-
A
A
D
Y
------------
L
D
K
D
---------
T
Y
G
Y
V
G
D
V
T
H
I
N
K
R
V
I
E
E
F
L
E
N
R
Q
I
P
I
L
A
S
L
G
Y
S
K
E
G
D
M
L
N
I
N
A
D
Y
L
A
T
A
V
A
V
A
L
A
A
D
K
L
I
L
M
T
N
V
K
G
V
L
E
-
N
G
-------
A
V
L
E
K
I
T
S
H
Q
V
Q
E
K
I
D
T
A
V
I
T
A
G
M
I
P
K
I
E
S
A
A
K
T
V
A
A
G
V
G
Q
V
L
I
G
D
N
L
---------------------------
16
PsiBlast_PDB
48.46
34%
-2
- C1 -
-
3L86
2
ARGB_STRMU
A:
[39-261]
-----------------------------
I
V
I
K
I
G
G
V
A
--
S
Q
Q
L
S
G
D
F
L
S
Q
I
K
N
W
Q
D
A
G
K
Q
L
V
I
V
H
G
G
G
F
A
I
N
K
L
M
E
E
N
Q
V
P
V
K
K
I
N
G
L
R
V
T
S
K
D
-----
D
M
V
L
---
V
S
H
A
L
L
D
L
V
G
K
-------------
N
L
Q
E
K
L
R
Q
A
G
V
S
-
C
Q
Q
L
K
S
D
I
K
H
V
V
A
A
D
YLDKD
T
Y
G
Y
V
G
D
V
T
H
I
N
K
R
V
I
E
E
F
L
E
N
R
Q
I
P
I
L
A
S
L
G
Y
S
K
E
G
D
M
L
N
I
N
A
D
Y
L
A
T
A
V
A
V
A
L
A
A
D
K
L
I
L
M
T
N
V
K
G
V
L
--
E
N
--
G
----
A
V
L
E
K
I
T
S
H
Q
V
Q
E
K
I
D
T
A
V
I
T
A
G
M
I
P
K
I
E
S
A
A
K
T
V
A
A
G
V
------------------------------------