@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTE5: (2017-12-13 )
MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ
Atome Classification :
(61 SA)
--.........10........20........30....--....40........50....---....60..--------.......70........80........90........100..-..-...110.......120..-.-....130.-----......140.......150
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--
M
K
V
Q
V
K
LLDPRLGKEWPLPSYATAGSAG
L
D
L
R
A
C
L
--
D
E
A
I
EIEPG
Q
T
V
L
V
KT
G
M
A
I
---
Y
I
HDV-
N
F
--------
A
G
L
I
LPRSGLGHKHG
I
V
L
G
N
L
V
G
LIDSDYQG
E
L
M
V
S
V
WNRG
Q
-
T
T
-
F
R
LE
P
G
E
R
L
A
Q
Y
V
L
V
P
V
V
-
Q
-
A
E
F
E
Q
V
E
E
-----
F
E
E
T
L
RGAGGFGHTGKQ
4
PsiBlast_PDB
94.23
70%
-164
- C4 -
-
2HR6
2
DUT_ECOLI
A:
[4-137]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
D
---------------
5
PsiBlast_PDB
92.99
70%
-165
- C4 -
-
2HRM
2
DUT_ECOLI
A:
[4-137]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
D
---------------
6
PsiBlast_PDB
92.65
70%
-150
- C4 -
-
1EUW
2
DUT_ECOLI
A:
[4-136]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
----------------
1
PsiBlast_PDB
92.45
70%
-156
- C4 -
-
1DUP
-
DUT_ECOLI
A:
[4-136]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
----------------
3
PsiBlast_PDB
90.97
70%
-165
- C4 -
-
1DUD
1
DUT_ECOLI
A:
[4-136]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
----------------
8
PsiBlast_PDB
90.60
65%
-162
- C4 -
-
3TQZ
-
DUT_COXBU
A:
[7-141]
---
S
V
Q
L
K
I
L
D
K
R
L
G
S
E
F
P
L
P
A
Y
A
T
T
G
S
A
G
L
D
L
R
A
C
L
--
D
E
P
L
K
I
E
P
D
E
T
C
L
I
S
T
G
L
A
I
---
Y
L
G
H
S
-
N
V
--------
A
A
T
I
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
P
L
M
V
S
C
W
N
R
G
K
-
E
P
-
Y
T
I
N
P
G
D
R
I
A
Q
L
V
V
L
P
I
L
-
K
-
A
Q
F
A
V
V
E
E
-----
F
E
L
--------------
7
PsiBlast_PDB
90.46
69%
-153
- C4 -
-
1SYL
3
DUT_ECOLI
A:
[4-137]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
N
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
D
---------------
2
PsiBlast_PDB
90.01
70%
-155
- C4 -
-
1EU5
2
DUT_ECOLI
A:
[4-136]
---
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
----------------
9
PsiBlast_PDB
89.34
66%
-169
- C4 -
-
4LHR
1
DUT_BURTA
A:
[9-140]
--
M
K
L
D
L
K
I
L
D
A
R
M
-
R
D
Y
-
L
P
K
Y
A
T
T
G
S
A
G
L
D
L
R
A
C
L
--
D
A
P
V
T
L
K
P
G
D
T
A
L
V
P
T
G
L
A
I
---
H
L
A
D
P
-
G
Y
--------
A
A
L
I
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
E
L
M
I
S
T
W
N
R
G
Q
-
T
E
-
F
V
L
N
P
F
E
R
L
A
Q
L
V
I
V
P
V
V
-
Q
-
A
T
F
N
I
V
G
D
-----
F
----------------
145
HHSearch
88.83
70%
-90
- C4 -
-
1EUW
2
DUT_ECOLI
A:
[3-136]
--
K
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
-
D
P
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-----
F
----------------
135
Fugue
88.01
70%
-48
- C4 -
-
1DUP
-
DUT_ECOLI
A:
[1-136]
MM
K
K
I
D
V
K
I
L
D
P
R
V
G
K
E
F
P
L
P
T
Y
A
T
S
G
S
A
G
L
D
L
R
A
C
L
--
N
D
A
V
E
L
A
P
G
D
T
T
L
V
P
T
G
L
A
I
---
H
I
A
D
P
-
S
L
--------
A
A
M
M
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
Q
L
M
I
S
V
W
N
R
G
Q
-
D
S
-
F
T
I
Q
P
G
E
R
I
A
Q
M
I
F
V
P
V
V
-
Q
-
A
E
F
N
L
V
E
D
-------
F
--------------
147
HHSearch
86.53
67%
-93
- C4 -
-
3TQZ
-
DUT_COXBU
A:
[7-141]
---
S
V
Q
L
K
I
L
D
K
R
L
G
S
E
F
P
L
P
A
Y
A
T
T
G
S
A
G
L
D
L
R
A
C
L
--
D
E
P
L
K
I
E
P
D
E
T
C
L
I
S
T
G
L
A
I
---
Y
L
G
-
H
S
N
V
--------
A
A
T
I
L
P
R
S
G
L
G
H
K
H
G
I
V
L
G
N
L
V
G
L
I
D
S
D
Y
Q
G
P
L
M
V
S
C
W
N
R
G
K
-
E
P
-
Y
T
I
N
P
G
D
R
I
A
Q
L
V
V
L
P
I
L
-
K
-
A
Q
F
A
V
V
E
E
-----
F
E
L
--------------
154
HHSearch
75.97
36%
-123
- C4 -
-
3HZA
4
DUT_MYCTU
A:
[25-171]
----
L
A
I
V
R
L
----
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
P
-
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
A
A
P
-
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
FDEAG
L
A
S
T
S
R
G
D
G
G
W
G
S
S
G
G
H
148
HHSearch
75.88
35%
-166
- C4 -
-
1Q5H
3
DUT_HUMAN
C:
[7-142]
--
M
Q
L
R
F
A
R
L
----
S
E
H
A
T
A
P
T
R
G
S
A
R
A
A
G
Y
D
L
Y
S
A
----
Y
D
Y
T
I
P
P
M
E
K
A
V
V
K
T
D
I
Q
I
---
A
L
P
-
S
-
G
C
--------
Y
G
R
V
A
P
R
S
G
L
A
A
K
H
F
I
D
V
--
G
A
G
V
I
D
E
D
Y
R
G
N
V
G
V
V
L
F
N
F
G
K
-
E
K
-
F
E
V
K
K
G
D
R
I
A
Q
L
I
C
E
R
I
F
-
Y
-
P
E
I
E
E
V
Q
A
-----
L
D
D
T
E
R
G
S
G
G
F
G
-----
34
PsiBlast_CBE
75.33
37%
-151
- C4 -
-
1Q5H
3
DUT_HUMAN
B:
[13-142]
------------
R
L
S
E
H
A
T
A
P
T
R
G
S
A
R
A
A
G
Y
D
L
Y
S
A
Y
--
D
--
Y
T
I
P
P
M
E
K
A
V
V
K
T
D
I
Q
I
---
A
L
P
S
G
-
C
Y
---------
G
R
V
A
P
R
S
G
L
A
A
K
H
F
I
D
V
G
--
A
G
V
I
D
E
D
Y
R
G
N
V
G
V
V
L
F
N
F
G
K
-
E
K
-
F
E
V
K
K
G
D
R
I
A
Q
L
I
C
E
R
I
F
-
Y
-
P
E
I
E
E
V
Q
A
-----
L
D
D
T
E
R
G
S
G
G
F
G
-----
33
PsiBlast_CBE
74.54
37%
-153
- C4 -
-
1Q5H
3
DUT_HUMAN
C:
[13-142]
------------
R
L
S
E
H
A
T
A
P
T
R
G
S
A
R
A
A
G
Y
D
L
Y
S
A
Y
--
D
--
Y
T
I
P
P
M
E
K
A
V
V
K
T
D
I
Q
I
---
A
L
P
S
G
-
C
Y
---------
G
R
V
A
P
R
S
G
L
A
A
K
H
F
I
D
V
G
--
A
G
V
I
D
E
D
Y
R
G
N
V
G
V
V
L
F
N
F
G
K
-
E
K
-
F
E
V
K
K
G
D
R
I
A
Q
L
I
C
E
R
I
F
-
Y
-
P
E
I
E
E
V
Q
A
-----
L
D
D
T
E
R
G
S
G
G
F
G
-----
157
HHSearch
74.40
36%
-126
- C4 -
-
4GCY
3
DUT_MYCTU
A:
[25-171]
----
L
A
I
V
R
L
----
D
P
G
L
P
L
P
S
R
A
W
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
P
-
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
A
A
P
-
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
FDEAG
L
A
S
T
S
R
G
D
G
G
H
G
S
S
G
G
H
21
PsiBlast_CBE
73.06
48%
-61
- C4 -
-
3MBQ
3
DUT_BRUA2
C:
[41-172]
---------------
K
G
L
D
L
P
A
Y
E
T
A
G
S
A
G
M
D
L
R
A
A
V
AE
D
R
Q
I
V
L
L
P
G
R
R
T
L
V
P
T
G
L
I
L
---
E
I
P
Q
--
G
Y
--------
E
V
Q
I
R
P
R
S
G
L
A
F
K
N
G
I
T
C
L
N
T
P
G
T
I
D
S
D
Y
R
G
E
V
K
V
L
L
I
N
L
G
D
-
D
D
-
F
R
I
E
R
G
M
R
I
A
Q
A
V
F
A
P
V
I
-
Q
-
P
K
I
E
E
R
A
K
-----
I
-----
G
A
G
G
F
------
25
PsiBlast_CBE
72.00
37%
-143
- C4 -
-
3EHW
3
DUT_HUMAN
X:
[30-164]
------------
R
L
S
E
H
A
T
A
P
T
R
G
S
A
R
A
A
G
Y
D
L
Y
S
A
Y
--
D
--
Y
T
I
P
P
M
E
K
A
V
V
K
T
D
I
Q
I
---
A
L
P
S
G
-
C
Y
---------
G
R
V
A
P
R
S
G
L
A
A
K
H
F
I
D
V
G
--
A
G
V
I
D
E
D
Y
R
G
N
V
G
V
V
L
F
N
F
G
K
-
E
K
-
F
E
V
K
K
G
D
R
I
A
Q
L
I
C
E
R
I
F
-
Y
-
P
E
I
E
E
V
Q
A
-----
L
D
D
T
E
R
G
S
G
G
F
G
S
T
G
K
N
23
PsiBlast_CBE
70.87
37%
-142
- C4 -
-
3EHW
3
DUT_HUMAN
Z:
[30-164]
------------
R
L
S
E
H
A
T
A
P
T
R
G
S
A
R
A
A
G
Y
D
L
Y
S
A
Y
--
D
--
Y
T
I
P
P
M
E
K
A
V
V
K
T
D
I
Q
I
---
A
L
P
S
G
-
C
Y
---------
G
R
V
A
P
R
S
G
L
A
A
K
H
F
I
D
V
G
--
A
G
V
I
D
E
D
Y
R
G
N
V
G
V
V
L
F
N
F
G
K
-
E
K
-
F
E
V
K
K
G
D
R
I
A
Q
L
I
C
E
R
I
F
-
Y
-
P
E
I
E
E
V
Q
A
-----
L
D
D
T
E
R
G
S
G
G
F
G
S
T
G
K
N
98
PsiBlast_CBE
70.62
39%
-134
- C4 -
-
3F4F
5
DUT_YEAST
C:
[40-163]
-------------------
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
Q
--
D
--
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
G
--
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
D
D
-
A
Q
I
V
V
V
D
S
-----
L
E
E
S
A
R
G
A
G
G
F
G
-----
164
HHSearch
68.32
38%
-131
- C4 -
-
3P48
2
DUT_YEAST
C:
[15-133]
--------------
S
A
S
A
T
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
----
Q
D
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
--
G
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
-
D
D
A
Q
I
V
V
V
D
S
-----
L
E
---------------
162
HHSearch
68.31
33%
-147
- C4 -
-
4OOP
3
DUT_ARATH
B:
[27-166]
--
P
F
F
K
V
K
K
L
----
S
E
K
A
V
I
P
T
R
G
S
P
L
S
A
G
Y
D
L
S
S
A
----
V
D
S
K
V
P
A
R
G
K
A
L
I
P
T
D
L
S
I
---
A
V
P
-
E
-
G
T
--------
Y
A
R
I
A
P
R
S
G
L
A
W
K
H
S
I
D
V
--
G
A
G
V
I
D
A
D
Y
R
G
P
V
G
V
I
L
F
N
H
S
D
-
A
D
-
F
E
V
K
F
G
D
R
I
A
Q
L
I
I
E
K
I
V
-
T
-
P
D
V
V
E
V
D
D
-----
L
D
E
T
V
R
G
D
G
G
F
G
S
T
G
V
-
36
PsiBlast_CBE
68.10
35%
-155
- C4 -
-
3C3I
4
?
C:
[3-137]
-------
S
L
L
V
K
K
L
V
E
S
A
T
T
P
M
R
G
S
E
G
A
A
G
Y
D
I
S
S
V
----
E
D
V
V
V
P
A
M
G
R
I
A
V
S
T
G
I
S
I
---
R
V
P
D
G
-
T
Y
---------
G
R
I
A
P
R
S
G
L
A
Y
K
Y
G
I
D
V
--
L
A
G
V
I
D
S
D
Y
R
G
E
V
K
V
I
L
Y
N
T
T
E
-
R
D
-
Y
I
I
K
K
G
D
R
I
A
Q
L
I
L
E
Q
I
V
-
T
-
P
G
V
A
V
V
L
D
-----
L
S
D
T
A
R
G
S
G
G
F
G
-----
71
PsiBlast_CBE
67.92
39%
-145
- C4 -
-
3P48
2
DUT_YEAST
C:
[20-133]
-------------------
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
Q
--
D
--
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
G
--
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
D
D
-
A
Q
I
V
V
V
D
S
-----
L
E
---------------
149
HHSearch
67.58
36%
-124
- C4 -
-
1SJN
4
DUT_MYCTU
B:
[3-140]
--
T
T
L
A
I
V
R
L
----
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
P
-
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
A
A
P
-
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
FDEAG
L
A
S
T
S
R
-----------
123
PsiBlast_CBE
67.51
36%
-111
- C4 -
-
1SJN
3
DUT_MYCTU
A:
[9-132]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
--------------
100
PsiBlast_CBE
67.37
39%
-138
- C4 -
-
3F4F
7
DUT_YEAST
A:
[40-163]
-------------------
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
Q
--
D
--
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
G
--
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
D
D
-
A
Q
I
V
V
V
D
S
-----
L
E
E
S
A
R
G
A
G
G
F
G
-----
152
HHSearch
67.29
35%
-139
- C4 -
-
2OKD
2
?
C:
[14-131]
------------
K
E
T
N
R
A
K
S
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
----
Y
D
Y
T
I
P
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
-
K
-
F
C
--------
Y
G
R
I
A
P
R
S
G
L
S
-
L
K
G
I
D
I
--
G
G
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
116
PsiBlast_CBE
66.86
36%
-117
- C4 -
-
1SLH
4
DUT_MYCTU
C:
[29-150]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
----------------
101
PsiBlast_CBE
66.61
36%
-142
- C4 -
-
5F9K
2
DUT_DICDI
C:
[9-128]
------------
K
L
S
D
K
A
I
I
P
Q
R
G
S
K
G
A
A
G
Y
D
L
S
S
A
----
H
E
L
V
V
P
A
H
G
K
A
L
A
M
T
D
L
Q
I
---
A
I
P
D
G
-
T
Y
---------
G
R
I
A
P
R
S
G
L
A
W
K
N
F
I
D
C
G
--
A
G
V
I
D
S
D
Y
R
G
N
V
G
V
V
L
F
N
H
S
D
-
V
D
-
F
K
V
A
V
G
D
R
V
A
Q
L
I
F
E
R
I
V
-
T
-
P
E
P
L
E
V
D
E
-----
I
D
---------------
160
HHSearch
66.23
36%
-154
* C4 *
-
3C3I
3
?
D:
[9-131]
-------------
L
V
E
S
A
T
T
P
M
R
G
S
E
G
A
A
G
Y
D
I
S
S
V
----
E
D
V
V
V
P
A
M
G
R
I
A
V
S
T
G
I
S
I
---
R
V
P
-
D
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
Y
K
Y
G
I
D
V
--
L
A
G
V
I
D
S
D
Y
R
G
E
V
K
V
I
L
Y
N
T
T
E
-
R
D
-
Y
I
I
K
K
G
D
R
I
A
Q
L
I
L
E
Q
I
V
-
T
-
P
G
V
A
V
V
L
D
-----
L
S
D
T
A
R
-----------
102
PsiBlast_CBE
65.96
36%
-131
- C4 -
-
5F9K
2
DUT_DICDI
B:
[9-130]
------------
K
L
S
D
K
A
I
I
P
Q
R
G
S
K
G
A
A
G
Y
D
L
S
S
A
----
H
E
L
V
V
P
A
H
G
K
A
L
A
M
T
D
L
Q
I
---
A
I
P
D
G
-
T
Y
---------
G
R
I
A
P
R
S
G
L
A
W
K
N
F
I
D
C
G
--
A
G
V
I
D
S
D
Y
R
G
N
V
G
V
V
L
F
N
H
S
D
-
V
D
-
F
K
V
A
V
G
D
R
V
A
Q
L
I
F
E
R
I
V
-
T
-
P
E
P
L
E
V
D
E
-----
I
D
E
T
-------------
110
PsiBlast_CBE
65.54
36%
-118
- C4 -
-
1SMC
5
DUT_MYCTU
C:
[29-150]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
----------------
118
PsiBlast_CBE
65.46
36%
-117
- C4 -
-
1SLH
4
DUT_MYCTU
A:
[29-153]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
103
PsiBlast_CBE
65.45
36%
-138
- C4 -
-
5F9K
2
DUT_DICDI
A:
[9-128]
------------
K
L
S
D
K
A
I
I
P
Q
R
G
S
K
G
A
A
G
Y
D
L
S
S
A
----
H
E
L
V
V
P
A
H
G
K
A
L
A
M
T
D
L
Q
I
---
A
I
P
D
G
-
T
Y
---------
G
R
I
A
P
R
S
G
L
A
W
K
N
F
I
D
C
G
--
A
G
V
I
D
S
D
Y
R
G
N
V
G
V
V
L
F
N
H
S
D
-
V
D
-
F
K
V
A
V
G
D
R
V
A
Q
L
I
F
E
R
I
V
-
T
-
P
E
P
L
E
V
D
E
-----
I
D
---------------
112
PsiBlast_CBE
65.41
36%
-112
- C4 -
-
1SMC
5
DUT_MYCTU
A:
[29-152]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
--------------
61
PsiBlast_CBE
65.40
38%
-155
- C4 -
-
2OL0
3
?
A:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
113
PsiBlast_CBE
65.32
36%
-112
- C4 -
-
1SM8
3
DUT_MYCTU
C:
[29-150]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
----------------
161
HHSearch
65.27
36%
-153
- C4 -
-
3C3I
4
?
C:
[9-137]
-------------
L
V
E
S
A
T
T
P
M
R
G
S
E
G
A
A
G
Y
D
I
S
S
V
----
E
D
V
V
V
P
A
M
G
R
I
A
V
S
T
G
I
S
I
---
R
V
P
-
D
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
Y
K
Y
G
I
D
V
--
L
A
G
V
I
D
S
D
Y
R
G
E
V
K
V
I
L
Y
N
T
T
E
-
R
D
-
Y
I
I
K
K
G
D
R
I
A
Q
L
I
L
E
Q
I
V
-
T
-
P
G
V
A
V
V
L
D
-----
L
S
D
T
A
R
G
S
G
G
F
G
-----
121
PsiBlast_CBE
65.10
36%
-113
- C4 -
-
1SJN
3
DUT_MYCTU
C:
[9-133]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
165
HHSearch
65.05
38%
-124
- C4 -
-
3P48
2
DUT_YEAST
B:
[15-132]
--------------
S
A
S
A
T
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
----
Q
D
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
--
G
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
-
D
D
A
Q
I
V
V
V
D
S
-----
L
----------------
108
PsiBlast_CBE
64.81
36%
-113
- C4 -
-
1SNF
4
DUT_MYCTU
B:
[29-153]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
117
PsiBlast_CBE
64.59
36%
-113
- C4 -
-
1SLH
4
DUT_MYCTU
B:
[29-153]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
119
PsiBlast_CBE
64.58
36%
-111
- C4 -
-
1SIX
2
DUT_MYCTU
A:
[29-153]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
107
PsiBlast_CBE
64.55
36%
-117
- C4 -
-
1SNF
4
DUT_MYCTU
C:
[29-150]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
----------------
99
PsiBlast_CBE
64.49
39%
-129
- C4 -
-
3F4F
6
DUT_YEAST
B:
[40-163]
-------------------
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
Q
--
D
--
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
G
--
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
D
D
-
A
Q
I
V
V
V
D
S
-----
L
E
E
S
A
R
G
A
G
G
F
G
-----
122
PsiBlast_CBE
64.15
36%
-109
- C4 -
-
1SJN
3
DUT_MYCTU
B:
[9-133]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
A
-------------
115
PsiBlast_CBE
64.03
36%
-115
- C4 -
-
1SM8
3
DUT_MYCTU
A:
[29-152]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
--------------
67
PsiBlast_CBE
63.91
38%
-148
- C4 -
-
2OKD
4
?
A:
[22-132]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
D
---------------
109
PsiBlast_CBE
63.89
36%
-112
- C4 -
-
1SNF
4
DUT_MYCTU
A:
[29-152]
------------
R
L
D
P
G
L
P
L
P
S
R
A
H
D
G
D
A
G
V
D
L
Y
S
A
----
E
D
V
E
L
A
P
G
R
R
A
L
V
R
T
G
V
A
V
---
A
V
-
P
F
-
G
M
--------
V
G
L
V
H
P
R
S
G
L
A
T
R
V
G
L
S
I
V
N
S
P
G
T
I
D
A
G
Y
R
G
E
I
K
V
A
L
I
N
L
D
P
-
A
A
P
I
V
V
H
R
G
D
R
I
A
Q
L
L
V
Q
R
V
E
-
L
-
V
E
L
V
E
V
S
S
-----
F
D
E
--------------
59
PsiBlast_CBE
63.62
38%
-148
- C4 -
-
2OL0
5
?
C:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
60
PsiBlast_CBE
62.49
38%
-146
- C4 -
-
2OL0
5
?
B:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
70
PsiBlast_CBE
62.40
38%
-148
- C4 -
-
2OKB
3
?
A:
[12-113]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
-----------------------------
65
PsiBlast_CBE
62.39
38%
-153
- C4 -
-
2OKD
2
?
C:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
72
PsiBlast_CBE
62.38
39%
-138
- C4 -
-
3P48
2
DUT_YEAST
B:
[20-132]
-------------------
V
P
T
K
G
S
A
T
A
A
G
Y
D
I
Y
A
S
Q
--
D
--
I
T
I
P
A
M
G
Q
G
M
V
S
T
D
I
S
F
---
T
V
P
-
V
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
V
K
N
G
I
Q
T
G
--
A
G
V
V
D
R
D
Y
T
G
E
V
K
V
V
L
F
N
H
S
Q
-
R
D
-
F
A
I
K
K
G
D
R
V
A
Q
L
I
L
E
K
I
V
D
D
-
A
Q
I
V
V
V
D
S
-----
L
----------------
159
HHSearch
62.08
35%
-135
- C4 -
-
5F9K
2
DUT_DICDI
B:
[5-130]
----
F
K
V
K
K
L
----
S
D
K
A
I
I
P
Q
R
G
S
K
G
A
A
G
Y
D
L
S
S
A
----
H
E
L
V
V
P
A
H
G
K
A
L
A
M
T
D
L
Q
I
---
A
I
P
-
D
-
G
T
--------
Y
G
R
I
A
P
R
S
G
L
A
-
W
K
N
F
I
D
C
-
G
A
G
V
I
D
S
D
Y
R
G
N
V
G
V
V
L
F
N
H
S
D
-
V
D
-
F
K
V
A
V
G
D
R
V
A
Q
L
I
F
E
R
I
V
-
T
-
P
E
P
L
E
V
D
E
-----
I
D
E
T
-------------
64
PsiBlast_CBE
61.53
38%
-153
- C4 -
-
2OKE
2
?
A:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
62
PsiBlast_CBE
61.06
38%
-147
- C4 -
-
2OKE
3
?
C:
[22-131]
--------------------
P
T
R
Q
S
P
G
A
A
G
Y
D
L
Y
S
A
Y
--
D
Y
T
I
P
--
P
G
E
R
Q
L
I
K
T
D
I
S
M
---
S
M
P
K
F
-
C
Y
---------
G
R
I
A
P
R
S
G
L
S
L
K
-
G
I
D
I
G
G
--
G
V
I
D
E
D
Y
R
G
N
I
G
V
I
L
I
N
N
G
K
-
C
T
-
F
N
V
N
T
G
D
R
I
A
Q
L
I
Y
Q
R
I
Y
-
Y
-
P
E
L
E
E
V
Q
S
-----
L
----------------
156
HHSearch
50.21
31%
-10
- C4 -
-
3T64
2
?
A:
[1-167]
--
M
H
L
K
I
V
C
L
S
D
E
V
R
E
M
Y
K
N
H
K
T
H
H
E
G
D
S
G
L
D
L
F
I
V
----
K
D
E
V
L
K
P
K
S
T
T
F
V
K
L
G
I
K
A
I
A
L
Q
Y
K
-
S
-
N
Y
Y
Y
KN
I
V
N
T
S
F
L
L
F
P
R
S
S
I
S
-
K
T
P
L
R
L
A
N
S
I
G
L
I
D
A
G
Y
R
G
E
I
I
A
A
L
D
N
T
S
D
-
Q
E
-
Y
H
I
K
K
N
D
K
L
V
Q
L
V
S
F
T
G
E
-
P
-
L
S
F
E
L
V
E
E
-----
L
D
E
T
S
R
G
E
G
G
F
G
S
----
155
HHSearch
46.69
31%
-24
- C4 -
-
3T64
2
?
B:
[1-155]
--
M
H
L
K
I
V
C
L
S
D
E
V
R
E
M
Y
K
N
H
------
D
S
G
L
D
L
F
I
V
----
K
D
E
V
L
K
P
K
S
T
T
F
V
K
L
G
I
K
A
I
A
L
Q
Y
K
-
S
-
N
Y
Y
Y
KN
I
V
N
T
S
F
L
L
F
P
R
S
S
I
S
-
K
T
P
L
R
L
A
N
S
I
G
L
I
D
A
G
Y
R
G
E
I
I
A
A
L
D
N
T
S
D
-
Q
E
-
Y
H
I
K
K
N
D
K
L
V
Q
L
V
S
F
T
G
E
-
P
-
L
S
F
E
L
V
E
E
-----
L
----------------