@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTG6: (2017-12-13 )
MTKFNNNQSDNLFSQVFGVAKKLSSTGLNILQQSQIGEVSKLVEPLSNGKTVEGSARNKSPFEVEQYESPLQMLREHLPKVTRQVFGRHFRKVNGIATFISPDWNEKISSYLFDWLNDFSSKSTLTEKILEEAGAKDLFELTKDTSRSQRLSQALIEQNKLIASIQGAITGVSGMVGAAVDIPVSLVLVLRTIYQTGRSHGFDLTEATDQDVVEFIFKEVDISLIAEKQTLLLALKALRNMLETQDIQQFQQVLGSSNDIETLKSWLVDENGKFKWNWLNKVPQLAVVGKFTPVAGAVLSAVYSWKLQEDVGHKAQAIFGAARHYLNEHPNEHLSPLQAYYAAVTLIQKASPRLLNVGENGSVHATQHHKIENHDVISKVSVVVKSNTSEKSEEKVQENVHQGIEHLAEKHVVEHEHSEQKPALEPESEENDDVIEGQKYS
Atome Classification :
(20 SA)
------------------------.........10........---20........30........------------------------40........-50........60........70....----...----.80.---.......90........100.......110.....-..120---------.......130.......140.......150.....---------..160.......170..-.....180-----.......----..190.......200.......210.......------220-....-------..-.230---........240......-.250.......260.--......270.......280.......-.290...--.--...300........310.......320.......330---.......340.--......350---------------...-......360.......370------------------.........380.......390.....--------..400--------.........410.......420...------------....430.......440---------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------MTKFNNNQS
D
N
L
F
S
Q
V
F
G
V
---
A
K
K
L
S
S
T
G
L
N
I
L
Q
Q
S
QI
G
E
V
------------------------
S
K
L
V
E
PLSNG-
K
T
VEGSARNKSP
F
E
V
E
Q
Y
E
S
P
L
Q
M
L
R
----
E
H
L
----
P
K
V
T
---
R
Q
V
F
G
R
H
F
R
K
VN
G
I
A
T
FISPD
W
N
E
K
I
S
S
Y
L
F
D
W
L
N
-
D
FSSK---------
S
T
L
T
E
K
I
L
E
EAG
A
K
D
L
F
E
L
T
KDT
S
R
S
Q
R
L
S
Q
A
L
I
E
---------
Q
N
K
L
I
A
S
I
Q
G
A
I
TGVSG-MVGA
A
V
-------
D
I
P
V
S
L
V
----
L
V
L
R
T
I
Y
Q
TGRSHGFDLTEAT
D
Q
D
V
V
E
F
I
F
K
E------VD
I
-
S
L
I
A-------E
K
-
Q
T
L
----
L
L
A
L
K
A
L
R
N
M
L
E
T
Q
D
I
Q
-
Q
F
Q
Q
V
LGSSN
D
I
E
T
L
--
K
S
W
L
VDENG
K
F
K
W
N
WLN-KVPQ
L
A
V
V
-GKFT
P
V
A
--
G
--
A
V
L
S
-
A
V
Y
S
W
K
L
Q
E
DVG
H
K
A
Q
A
I
F
G
A
A
R
H
Y
L
N
EHPNE---
H
L
S
P
L
Q
A
Y
Y
A
A
--
V
T
L
I
Q
KA-----------------SP
R
-
L
L
N
VGENG
S
V
H
A
T
Q
HHK--------------------IE
N
H
D
V
I
S
K
V
S
V
V
V
KSNTSE
K
S
E
E
K
V
Q
--------
E
N
V
----------
H
Q
G
I
E
H
L
A
E
K
H
V
V
E
HEHSEQKPALE------------PESEENDDVIEGQKYS----------------------------------------------------
35
Fugue
70.85
18%
-3
- C9 -
-
5L3T
-
THP1_YEAST
B:
[1-455]
-----------------------------
M
D
M
A
N
Q
L
L
D
E
L
A
-------
H
G
N
F
S
H
L
T
L
N
L
S
Q
N
G
R
E
I
------------------------
A
I
L
Q
K
Q
L
T
-------
G
F
D
D
K
Q
L
E
T
F
V
E
Q
H
P
A
---
M
P
N
----
D
T
R
----
F
K
I
M
---
C
T
S
F
L
N
Y
A
R
D
V
D
P
W
S
A
W
S
S
S
D
L
I
F
E
F
Y
Q
C
L
I
N
C
L
I
-
N
D
N
A
P
H
I
E
M
L
I
P
V
A
T
R
E
T
E
F
I
I
N
L
A
G
K
L
D
S
F
H
L
Q
L
H
T
R
S
H
Q
F
L
S
H
I
S
S
I
---------
L
S
R
L
F
N
S
I
K
P
P
R
G
N
A
S
S
T
N
I
P
G
K
Q
-------
R
I
L
L
Y
L
V
----
N
K
L
N
N
I
Y
F
R
I
E
S
----------
P
Q
L
C
S
N
I
F
K
N
------
F
Q
P
K
S
M
L
A
HFNEYQ
L
D
Q
-
Q
I
E
----
Y
R
Y
L
L
G
R
Y
Y
L
L
N
S
Q
V
H
N
-
A
F
V
Q
F
N
E
A
F
Q
S
L
L
N
L
PL
T
N
Q
A
I
T
R
N
G
T
R
I
L
N
Y
M
---
I
P
T
G
L
I
L
-
G
K
M
V
K
W
G
--
P
LR
P
F
L
S
-
Q
E
T
I
D
N
W
S
V
L
Y
K
H
V
R
Y
G
N
I
Q
G
V
S
L
W
L
R
Q
N
-
E
R
---
H
L
C
A
R
Q
L
L
I
V
L
--
L
E
K
L
P
M
V
-----------------
T
Y
R
N
L
I
K
T
V
I
K
S
W
T
T
E
W
G
Q
N
K
--------------------
L
P
Y
S
L
I
E
R
V
L
Q
L
S
I
G
P
T
F
E
D
P
G
A
Q
E
I
T
IYNGIHSP
K
N
V
----------
E
N
V
L
V
T
L
I
N
L
G
L
L
R
A
N
C
F
P
Q
L
Q
L
C
V
V
K
KTTM
I
Q
E
I
V
P
P
V
N
E
R
I
T
K
M
F
P
A
H
S
H
V
LW--------------------------------------------------
40
Fugue
58.78
15%
-22
- C6 -
-
5T6O
-
PHAC_CUPNH
A:
[1-389]
--------------------------------------
S
A
F
E
V
---
G
R
N
V
A
V
T
E
G
A
V
V
F
E
N
E
Y
F
Q
L
------------------------
L
Q
Y
------------------
K
P
L
T
D
K
V
H
A
R
P
L
L
M
V
------------
P
P
C
I
---
N
K
Y
Y
I
L
D
L
Q
P
E
S
S
L
V
R
H
V
V
E
---
Q
G
H
T
V
F
L
V
S
W
R
N
P
D
A
S
M
A
---------
G
S
T
W
D
D
Y
I
E
H
A
-
A
I
R
A
I
E
V
A
R
D
I
S
G
Q
D
K
I
N
V
L
G
F
----------------
A
V
G
G
T
I
V
S
T
A
L
-
A
V
L
A
A
R
G------
E
H
P
A
A
S
V
----
T
L
L
T
T
L
L
D
F
A
D
T
G
I
L
D
V
F
V
D
E
G
H
V
Q
G
A
P
C
A
L
L
------
R
G
L
-
E
L
A
N
-------
T
F
-
S
F
L
RPND
L
V
W
N
Y
V
V
D
N
Y
L
K
G
N
T
P
V
-
P
F
D
L
L
F
W
N
G
D
A
-
T
N
L
--
P
G
P
W
Y
C
W
Y
L
R
H
T
Y
L
Q
N
E
L
K
V
P
G
K
L
T
V
-
C
G
V
P
V
D
L
--
A
--
S
I
D
V
-
P
T
Y
I
Y
G
S
R
E
D
-------------------------
H
I
V
P
W
T
A
A
Y
A
S
--
T
A
L
L
A
N
-------------------
K
L
-
R
F
V
L
G
A
S
G
H
I
A
G
V
I
N
P
P
--------------------
A
K
N
K
R
------
S
H
W
T
N
D
A
L
P
E
S
P
Q
Q
W
L
--------
A
G
A
----------
I
E
H
H
G
S
W
W
P
D
W
T
A
W
L
A
G
Q
A
G
A
K
R
A
A
------------
P
A
N
Y
G
N
A
R
Y
R
A
I
E
P
A
P
GRYVKAKA--------------------------------------------
39
Fugue
58.11
11%
-40
- C9 -
-
3FGA
1
2A5G_HUMAN
B:
[1-403]
----------------------------
P
P
A
D
Q
E
K
L
F
I
Q
K
L
R
Q
---
C
----
C
V
L
F
D
F
V
S
D
P
L
S
D
L
K
------------------------
W
K
E
V
K
R
A
A
L
S
-
E
M
V
E
Y
I
T
H
N
R
N
V
I
T
E
P
I
Y
P
E
V
V
H
M
F
A
----
V
N
M
FRTL
P
P
S
S
---
N
P
T
G
A
E
F
D
P
E
E
D
E
P
T
L
E
A
A
W
P
H
L
Q
L
V
Y
E
F
F
L
R
F
L
E
-
S
P
D
F
Q
---------
P
N
I
A
K
K
Y
I
D
Q
K
F
V
L
Q
L
L
E
L
F
D
--
S
E
D
P
R
E
R
D
F
L
------------
K
T
T
L
H
R
I
Y
G
K
F
L
G
L
R
A
-
Y
I
R
K
Q
I
-------
N
-----
N
----
I
F
Y
R
F
I
Y
E
T
E
H
H
N
G
--
I
A
E
L
L
E
--
I
L
G
S
I
I
N
G
------
F
A
L
-
P
L
K
E
-------
E
H
-
K
I
F
----
L
L
K
--
V
L
L
P
L
H
K
V
K
S
L
S
-
V
Y
------
H
P
Q
L
A
Y
C
--
V
V
Q
F
L
E
K
D
S
T
L
T
E
P
V
V
M
-
A
L
L
K
-------
Y
W
P
K
T
--
H
--
S
P
K
E
-
V
M
F
L
N
E
L
E
E
I
L
D
V
I
E
P
S
E
F
V
K
I
M
E
P
L
F
R
Q
L
A
K
---
C
V
S
S
P
H
F
Q
V
A
E
--
R
A
L
Y
Y
W
N
-----------------
N
E
Y
-
I
M
S
L
I
S
D
N
-------------------------------
A
A
K
I
L
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
N
K
T
I
H
--------
G
L
I
----------
Y
N
A
L
K
L
F
M
E
M
N
Q
K
L
F
D
D
C
T
Q
Q
F
K
A
E
------------
K
L
K
E
K
L
K
M
K
E
R
E
E
A
W
V
K
IENL-----------------------------------------------
36
Fugue
55.20
12%
-70
* C9 *
-
2JAK
-
2A5G_HUMAN
A:
[30-372]
------------------------
I
R
D
V
P
A
D
Q
E
K
L
F
I
Q
K
L
R
Q
C
---
C
V
L
F
D
F
V
S
D
P
L
S
D
L
K
W
K
E
V
K
------------------------
R
A
A
L
S
E
M
V
E
Y
-
I
T
-----
H
N
R
N
V
I
T
E
P
I
Y
P
E
V
V
H
M
F
A
----
V
N
M
------------------
F
R
T
L
P
P
P
T
L
E
A
A
W
P
H
L
Q
L
V
Y
E
F
F
L
R
F
L
E
-
S
P
D
F
Q
---------
P
N
I
A
K
K
Y
I
D
Q
K
F
V
L
Q
L
L
E
L
-------------------------------------------
F
D
S
E
D
P
-------
R
E
R
D
F
L
K
----
T
T
L
H
R
I
Y
G
K
F
L
G
L
R
A
Y
I
R
K
Q
I
N
N
I
F
Y
R
F
I
Y
E
T
------
E
H
H
-
N
G
I
A
-------
E
L
L
E
I
L
----
G
S
I
I
N
G
F
A
L
P
L
K
E
E
H
K
I
-
F
L
L
K
V
L
L
P
L
H
K
V
K
S
L
--
S
V
Y
-
H
P
Q
L
A
Y
C
V
V
Q
F
L
E
-
K
D
S
T
L
T
------
E
P
V
V
--
M
--
A
L
L
K
----
Y
W
P
K
T
H
S
--
P
K
E
V
M
F
L
N
E
L
E
E
I
L
D
V
I
E
P
S
---
E
F
V
K
I
M
E
P
L
F
R
--
Q
L
A
K
C
V
S
-----------------
S
P
H
-------------------------------------------------------------
F
Q
V
A
--------
E
R
A
----------
L
Y
Y
W
N
N
E
Y
I
M
S
L
I
S
D
N
A
A
K
I
L
P
I
M
F
------------
P
-------------------------------------------------------------------
33
Fugue
53.71
15%
61
* C8 *
-
5MB9
1
?
A:
[23-578]
G
E
R
V
V
I
G
I
T
F
G
NS
N
S
S
I
A
H
T
V
DD
K
A
E
V
I
A
N
E
D
G
D
R
Q
I
P
T
I
L
S
Y
V
DG
D
E
Y
Y
G
Q
Q
A
K
N
F
L
V
R
N
P
K
N
T
V
------------------------
A
Y
F
R
D
I
L
G
Q
D
F
K
S
V
D
P
T
H
N
H
A
S
A
H
P
Q
E
A
G
D
N
V
V
F
T
I
K
DKAE
E
D
A
----
E
P
S
T
---
L
T
V
S
E
I
A
T
R
Y
L
R
R
L
V
G
A
A
S
E
Y
L
G
K
K
V
T
S
A
V
I
T
I
P
T
-
N
F
T
------------
E
K
Q
K
A
A
L
I
A
A
A
A
A
A
D
L
E
V
L
Q
L
I
S
E
P
A
A
A
V
L
A
Y
D
A
---------
R
P
E
--
A
T
I
S
D
K
I
I
V
V
A
D
-
L
G
G
S
R
S
-------
D
V
T
V
L
A
S
R
SG
M
Y
T
I
L
A
T
V
H
D
Y
E
Y
H
G
I
A
L
D
K
V
L
I
D
H
F
S
K
E
F
L
K
K
N
PGAKD
P
R
E
-
N
P
R
S
-------
L
A
-
K
L
R
----
L
E
A
E
S
T
K
R
A
L
S
R
S
T
N
A
S
F
S
V
E
S
L
I
D
G
L
D
F
A
S
T
I
--
N
R
L
R
Y
E
T
I
A
R
T
V
F
E
G
F
N
-
R
L
V
E
S
A
V
K
K
A
G
L
D
P
L
D
VD
E
--
V
I
M
S
-
G
G
T
S
N
T
--
P
R
I
A
A
N
F
R
Y
I
F
P
E
S
T
R
I
L
A
P
S
T
D
P
SAL
N
P
S
E
L
Q
A
R
G
A
A
L
Q
A
S
L
I
Q
E
F
-----------------
E
T
E
-
D
I
E
Q
S
T
H
A
A
V
T
T
M
P
H
V
T
N
A
I
G
V
V
S
V
SKFVPIIAPETA
V
P
A
R
R
T
V
H
G
G
D
V
L
V
K
V
V
E
G
S
T
H
I
N
V
I
K
--------
R
E
K
----------
V
W
K
I
G
S
T
L
A
E
A
A
V
R
G
V
K
K
G
A
K
V
E
V
T
------------
I
N
V
N
T
D
L
T
V
I
V
T
A
R
E
V
----------------------------------------------------
32
Fugue
50.65
9%
-48
- C9 -
-
3O2T
1
SYMPK_HUMAN
A:
[21-331]
-----------------------------------------------------------
M
T
T
S
E
R
V
------------------------
V
D
L
L
N
Q
A
A
L
I
-
T
N
-------------
D
S
K
I
T
V
L
K
Q
V
Q
----
E
L
I
----
I
N
K
D
---
P
T
L
L
D
N
F
L
D
E
I
I
A
F
Q
A
----
D
K
S
I
E
V
R
K
F
V
I
G
F
I
E
-
E
A
C
K
R
-------------
D
I
E
L
L
L
K
L
I
A
N
L
N
M
L
L
R
D
E
N
-----------------------------------
V
N
-
V
V
K
K
A
I
-------
L
T
M
T
Q
L
Y
K
---
V
A
L
Q
W
M
V
K
S
V
I
S
E
L
Q
E
A
C
W
D
M
V
S
A
M
A
G
D
I
I
L
L
------
L
D
S
-
D
----------
N
D
-
G
I
R
----
T
H
A
I
K
F
V
E
G
L
I
V
T
L
S
P
R
-
M
A
D
S
E
I
P
R
R
Q
E
------------------------
H
D
I
S
L
D
R
I
-
P
R
D
H
P
Y
I
--
Q
--------------
Y
N
V
L
W
E
E
G
K
A
A
L
E
Q
L
L
K
F
M
V
H
I
S
S
I
---
N
L
T
T
A
L
G
S
L
A
N
--
I
A
R
Q
----------------------------------------
R
--------------------
P
M
F
M
S
E
V
I
Q
A
Y
E
T
L
H
A
N
L
A
K
S
Q
V
S
S
V
R
--------
K
N
L
----------
K
L
H
L
L
S
V
L
K
H
P
A
S
L
E
F
Q
A
Q
I
T
T
L
L
V
------------
D
L
G
T
P
Q
A
E
I
A
R
N
M
P
------------------------------------------------------
37
Fugue
49.47
10%
9
- C4 -
-
1BKD
-
SOS1_HUMAN
S:
[568-1044]
--------------------------
R
L
P
S
A
D
V
Y
R
F
A
E
P
D
S
E
E
---
N
I
I
F
E
E
G
I
P
I
I
K
A
----
G
T
V
------------------------
I
K
L
I
E
R
L
T
Y
H
-
M
Y
A
D
P
N
F
V
R
T
F
L
T
T
Y
R
S
F
C
K
P
Q
E
L
L
S
----
L
I
I
----
E
R
F
E
IPE
P
R
F
R
K
E
Y
I
Q
P
V
Q
L
R
V
L
N
V
C
R
H
W
V
E
H
H
F
Y
D
F
E
R
D
A
Y
-
L
L
Q
R
M
---------
E
E
F
I
G
T
V
R
G
K
A
M
K
K
W
V
E
S
I
T
K
I
I
Q
R
K
K
I
T
F
Q
S
S
P
P
---------
T
V
E
W
H
I
S
R
P
G
H
I
E
T
F
D
L
-
L
T
L
H
P
I
-------
E
I
A
R
Q
L
T
----
L
L
E
S
D
L
Y
R
A
V
Q
P
S
E
L
V
G
S
V
W
T
K
E
D
K
E
I
N
S
P
N
L
------
L
K
M
-
I
R
H
T
-------
T
N
-
L
T
L
----
W
F
E
K
C
I
V
E
T
E
N
L
E
E
R
V
A
-
V
V
S
R
I
I
E
I
L
Q
V
F
Q
E
L
--
N
N
----------
F
N
G
V
L
-
E
V
V
S
A
M
N
S
-
S
P
V
Y
R
L
D
--
H
--
T
F
E
Q
I
P
S
R
Q
K
K
I
L
E
E
A
H
E
L
S
E
D
H
Y
K
K
Y
L
A
K
L
R
S
I
N
P
P
---
C
V
P
F
F
G
I
Y
L
T
N
--
I
L
K
T
E
E
G
-----------------
N
P
E
-
V
L
K
R
H
G
K
E
L
I
N
F
S
K
R
R
K
--------------------
V
A
--
E
I
T
G
E
I
Q
Q
Y
Q
N
Q
P
Y
C
L
R
V
E
S
D
I
K
--------
R
F
F
ENLNPMGNSM
E
K
E
F
T
D
Y
L
F
N
K
S
L
E
I
E
P
R
N
P
K
P
L
P
R
------------
F
P
K
K
Y
S
Y
P
L
K
S
P
G
V
R
P
SN--------------------------------------------------
34
Fugue
38.11
13%
-69
- C8 -
-
3HM5
-
A:
[15-88]
------------------------------------------------------------------------------------------------------------------------------------
Q
V
----
P
V
Y
S
---
E
Q
E
Y
Q
L
Y
L
H
---------
D
D
A
W
T
K
A
E
T
D
H
L
F
D
L
S
R
-
R
F
D
L
R
---------
F
V
V
I
H
D
R
Y
D
H
Q
Q
F
K
K
R
-
S
V
E
D
L
K
E
R
Y
Y
H
I
C
A
K
L
A
N
---------
V
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
33.10
27%
-13
- C10 -
-
2GZ1
1
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
32.29
11%
46
- C5 -
-
3NSJ
4
PERF_MOUSE
A:
[1-531]
-----------------------P
C
Y
T
A
T
R
S
E
C
K
Q
K
H
K
F
V
P
G
V
---
W
M
--
A
G
E
G
M
D
V
T
T
L
R
R
S
G
S
F
PVNTQRFLRPDR
T
C
T
L
C
K
N
SLMRD
A
T
Q
R
L
P
V
A
I
T
-
H
W
R
P
H
S
S
H
C
Q
R
N
V
A
A
A
K
V
H
S
T
E
G
V
A
R
----
E
A
A
----
A
N
I
N
---
N
D
W
R
V
G
L
D
V
N
R
P
E
A
N
M
R
A
S
V
A
G
S
---
H
S
K
V
A
N
F
A
A
-
E
K
T
Y
Q
---------
D
Q
Y
N
F
N
S
D
T
V
E
C
R
M
Y
S
F
R
L
V
Q
K
P
P
L
H
L
D
F
K
K
A
L
R
A
LPRNFNSST
E
H
A
Y
H
E
L
I
S
S
Y
G
T
H
F
I
T
-
A
V
D
L
G
G
-------
R
I
S
V
L
T
A
----
L
R
T
C
Q
L
T
L
N
G
L
T
-
A
D
E
V
G
D
C
L
N
V
E
A
Q
V
S
I
G
A
Q
------
A
S
V
-
S
S
E
Y
-------
K
A
-
C
E
E
----
K
K
K
Q
H
K
M
A
T
S
F
H
Q
T
Y
R
E
-
R
H
V
E
V
L
G
G
P
L
D
S
T
H
D
--
L
L
F
G
N
Q
A
T
P
E
Q
F
S
T
W
T
A
-
S
L
P
S
N
P
G
L
-
V
D
Y
S
L
E
P
-------------
L
H
T
L
L
E
E
Q
N
P
K
R
E
A
L
R
Q
A
I
S
H
Y
I
M
S
R
A
R
W
---
Q
N
C
S
R
P
C
R
S
G
Q
--
H
K
S
S
H
D
S
C
Q
C
E
C
QDSKVTNQDCCP
R
Q
R
-
G
L
A
H
L
V
V
S
N
F
R
A
E
H
L
W
G
--------------------
D
Y
T
T
A
T
D
A
Y
L
K
V
F
F
G
G
Q
E
F
R
T
G
V
V
W
N
N
--------
N
N
P
----------
R
W
T
D
K
M
D
F
E
N
V
L
L
S
T
G
G
P
L
R
V
Q
V
W
D
------------
A
D
Y
G
W
D
D
D
L
L
G
S
C
D
R
S
P
H
S
G
F
H
E
V
T
C
E
L
N
H
G
R
V
K
F
S
Y
H
A
K
C
L
PHLTGGTCL
E
Y
A
P
Q
G
L
L
G
DPPGNRSG
18
PsiBlast_PDB
32.25
27%
-9
* C10 *
-
4R3W
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
32.04
27%
-9
- C10 -
-
2GZ2
1
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
31.96
27%
-5
- C10 -
-
2GZ3
1
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
31.87
27%
-12
- C10 -
-
3PWK
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
31.53
27%
-12
- C10 -
-
3PWS
1
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
31.49
27%
-7
- C10 -
-
3PYX
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
31.38
27%
-3
- C10 -
-
3Q11
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
31.02
27%
-4
- C10 -
-
4R41
4
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
30.78
27%
-5
- C10 -
-
3PZB
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
30.67
27%
-6
- C10 -
-
4R4J
3
?
A:
[6-71]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
G
A
T
G
-
A
V
G
A
Q
M
I
K
M
L
E
E
S
T
L
P
I
D
K
I
----
R
Y
L
A
S
A
R
S
A
G
K
S
L
K
F
K
D
Q
D
I
T
I
E
E
T
T
E
T
A
F
E
G
------
V
D
I
-
A
L
F
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------