@TOME V2.3
(Mar 2018)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : B0VTI8: (2017-12-13 )
MQQSHFDMPEATQAVFNFFFPNGLFYQDSKGGVWEEGIIVVIELQAIDSNGDPVGSIITINQEIRANNKSQLGRTIYIDLPTAGSFRFRLSRTTATQAGKTQDTCKIKSVYGMADSSISDYGNVTVLRSRTVATDGALSIKERKLNCLVNRKLPLDGTGPLQVTRSAGQALINLALDEHIGRRTSAEVDIAQINAEIAKVKAYFGSDLMSEFNYTIDDDNLSFEEIAGMVASSAFCEPYRFGSLTRFKFEGLQENAVLLFKHRNKVPLTEKRSYTFGVQKDYDGVELEYTSDVDDARVKYIIPEDITPKNPLKITTTGIRNEAQAKVRAWREWNKLRYKYMSCEVEVLDESELLIRNDRILVANNTVVDTQDGEVEAVDGLIIQTSQECTFDVGSDYFIHLQISNATVDVVSCTAGVDKYHVVLSRPPVQPLVVSEDRYVKTLYTLVRADQTEAQAFMLEELTPQTQMTNTLKASNYDARFYERDHDFI

Atome Classification :

(20 SA) --------------------------------------------------------------------------------------------.........---10.....-...20........30....------....40...-...-..50...-.....60...---.....70........80....-----....90........100..----.....--110...-....120.......130....--...140--.......150.---......160--.......170.......180...-----.-----------------...190..----.....200.....---------..210.....-..---.220-.....--..230........240.-.----......250..-----...--..260----.------...----...270...-....280......---------.290-.......------.---.-300.-.-----.-.-.-..--..310......-.320...---------------....330.......---340----......-.350--.---....---------------------------....360...----..----------------------..370..-......380......---.390...--....400......-.410......-.---------420.......--------------------430...-....440.......450.......460-.........470........480.......
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) --------------------------------------------------------------------------------------------MQQSHFDMP---EATQAVF-NFFFPNGLFYQDSKGGVWE------EGIIVVIEL-QAI-DSNGDPV-GSIITINQEI---RANNKSQLGRTIYIDLPTAGS-----FRFRLSRTTATQAGKTQDT----CKIKS--VYGMAD-SSISDYGNVTVLRSRTVATDG--ALSIKE--RKLNCLVNRKL---PLDGTGPLQ--VTRSAGQALINLALDEHIGRRTS-----A-----------------EVDIAQIN----AEIAKVKAYFGSD---------LMS-EFNYTI-DD---DNLS-FEEIA--GMVA-SSAFCEPYRF-G-S----LTRFKFEGLQE-----NAV--LLFKH----R------NKV----PLTEKRSYT-FGVQKDYDGVELE---------YT---SDVDDAR------V---K-Y--I-I-----P-E-D-IT--PKNPLKITTTG-IRNEAQA---------------KVRAWREWNKLRYK---YMS----CEVEVL-DE----S---ELLI---------------------------RNDRILVANN----TV----------------------VDT-QDG-EVEAVDGLIIQTSQE---CTFDVGS--DYFIHLQISNATV-DVVSCTAGVD-K---------YHVVLSRPPV--------------------QPLVVS-EDRYVKTLYTLVRADQTEAQAFMLE---ELTPQTQMTNT-LKASNYDARFYERDHDFI
20 Fugue 61.7020% 57 - C4 - - 5GKD ? A:[1-726] ADLLVKTPEAYDQALKKAKPGDDIILANGTWRDFEVLFEAKGNENKPITLRGQTPGKVFLTGQSNLRLAGEHLIVSGLVFKDGYTPTGEVIAFRRNKDVLASHSRVTQVVI-DNFSNPEKFEQDSWVMVYG------RHN-RFDHN-HLV-GKRNKGV-TMAVRLTTES---SQQNHHRIDHNYFGPRPILGSNGGETLRIGTSHHSLTDSFTLVEN----NYFDR--CNGEVE-IISNKSGKNSIRNNVFFESRG--TLTLRH--GNGNIVENNVFFGNGVDHTGGIR--VINR-DQIIRNNYLEGLTGYRFG-----SGLTVMNGVPNSKINRYHQVDNALIENNTLVNVEHIQFAAGSDKERSAAPINSNM-NNNLIV-NDQGTDGITAFDDIS--GIKF-KDNLLNQDAK-P-S----INK----GFEQ-----ADI--TMQRH----D------NGL----LYPEAKTQQKYGVSTQLEPIGKDEVGVSWYPKVE---PDVAFGS------G---K-H--I-AVS---P-G-D-NT--LFDAIASAETG-DVLVLQAGEYWVSKILSLDKTLTIRAQEKGSAVIFP---QRS----TLIEIN-NK----G---NLTLDGVYVDATNAPDAAGNTLIRTTRLPMQRNYRLAIKNS----TFENLDINHSYHFFDAGNRSFADYIEV-QDS-QFKHITGDLFRLNKE----TDDLGI--YNVEYLTIENSNVSDLQGAIAKVY-RGGTDESTFGPHVVMNNNIFNEVGKGKRNKSAASLILHGTQVNKMT-TNEFNNSAPIIFELTVGEPKTWVTGNVFEGTPEPVVRDL-FPLSG--ATTTISGNTVL
24 Fugue 60.9120% -29 - C5 - - 2CY7 - ATG4B_HUMAN A:[5-377] ----------------------------------------------------------------------------------------------TLTYD-------------TLRFAEFEDFPETSEPVWI------LGRKY------------------SIFTEKDEI---LSDVASRLWFTYRKNFPAIGG-----------------TGPTSDT------------------------GWGCMLRCGQMIFAQ--ALVCRHLGRDWRWTQRKRQ---PDSYFSVLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYG-----------------PNTVAQVL----KKLAVF------D---------TWS-SLAVHIAMD---NTVV-MEEIR--RLCR-TSVPCSPWRP-------------------------LV--LLIPL----R------LGL----T-----------------DINEA---------YV---ETLKHC-------------F--M-M-----P-Q-S-L-----------------------------------------------------------------------------------------------------------------------------------------------------------------GVIGGKPNS---AHYFIGYVGEELIYLDPHTTQP-AVEGCFIPDE-S---------FHC--QHPPC--------------------RMSIAE-LDPSIAVGFFCKTEDDFNDWCQQVK---KLSLLPMFELVEQQPDVLNLSLDSSDVERL
25 Fugue 55.4619% 53 - C5 - - 4R5O ? A:[2-427] ------------------------------------------------------------------------------------------DDCEDLHLGNL---AHYPNVL-KGTFPT-------ESQVLE------LGETLEITP-ELL-NPEG-AT-YSWLVNGKEY---S----------------TEPT-----FSYKIDNPC-----RADLS----CIIKN--KYGKVEMS--------TSFSSNHNFSKG--FFYVAD--GTFNFYDTEK------------K--TAYQDCYASLNAGKTLGIGNY---------------------------DSANII----HSNGKFYLLVGTS---------TSNRDHFYIV-DA---KTLY-YENSAVVGANL-SGLTILNEQY-G-L----VTG---DGIRR-----ID-----LKS----L------NNV----RIKNERLLC-FYNSIIYNGKVLS---------ND---TYKDESK------V---K-Y--YDV-----N-E-L-IA--AKEGEAPAVTE-LDIIQKQ---------------KINFVLAKDGNVYT---LESADNGCNIVKI-KN----DFTLEKVF---------------------------ANFQPAKGPY----HS----------------------SPT-I-GMVASETENIIYLVSTDGAIYKYILGD--SDSLKAPFIAAES-G-VSITA---------------------------------------------PLQLN-QQS--GELYVTYTEERKDESKIVVY---SKDGKVLHTVD-CGESVPSQILFNN-----
17 Fugue 50.1324% 27 - C3 - - 5D8M - ? A:[8-339] ---------------------------------------------------------------------------------------------------RP---VAPLAHAMS---PSVLVPAGLAG--IQ------DGRGRFREIMTAIMADHGAFLPGDRSSDGDGILWRLAGEPGPTGRPVPLGVSTAG------IRLVLVPGLLA-------E----CVSESSLLFDDAR-PDVERYGYATTL----VRTGGRWGSARNA--AIIHEVVAKLP---ENDTIVFVT--HSKGAVDVLEALVSYPDLAARTA-----A-----------------VVSVAG-------------AIDGSP---------LAE-TFS-----D---GLLR-FAE-------SMPLSSCPP----G-E----GTEALDS-LKR-----AYR--LRFLA----E------HRL----P----------------------------------------------------------------------------------------------------------------------ARVRYY---SLA----AFASRE-ET----S---AILR---------------------------PFYDILAKTD----AL--------------------------NDG-LVIAADAII-------------------------------------------P---------GGTLLGYPNA--------------------DHLAVAMPFSKKPSLLTSVISKNSYPRPALLE---AIARYVEEDL--------------------
19 Fugue 49.1117% -0 - C2 - - 5TC1 - MATA_BPMS2 M:[1-393] -------------------------------------------------------------------------------------------MRAFSTLDRE---NETFVYR-SNWTPGRFNSTGAKTKQWHYPSPYSRGALSVTSI-FSL-DA--RSC-YSLFPVSQNL---T-----------YIEVPQNVA-----NRASTEVLQKVTQGNFNLG----VALAE--ARSTAS-Q----------LATQTIALVK--AYTAAR--RG--------------------------NWRQALRYLALNED--------------------------------------------RKFRSKHVAG---------RWL-ELQFGW-LP---LMSD-IQGAY--EMLT-KVHLQEFLPM-R-A----VRQVGTNIKLD-----G-------------Q------TTC----NISRRIVIW-FYI---------------------------NDAR------L---A-W--L-S-----S-L-G-IL----NPLGIV---------------------------------WEKVPFS---FVV----DWL---------------------------------------------------------------------------------------------LPVGNMLEGLTAP---VGCSYMS--GTVTDVITGESII-Q------GTA-K---------AQISAMHRGV--------------------QSVWPT-TGAYVKSPFS-------------------------MVHT-LDALALIRQRLSR-----
23 Fugue 48.8019% 3 - C5 - - 5AYC MGP_RUMA7 A:[1-386] -------------------------------------------------------------------------------------------MIHEKYTEMR---NEQEALL-SRKNTKTSFYNGI------------------------Y-DRYEHPV-LTREHIPLHW---RYD----------LNKETNPF-----FQERLG-------------------INA--VFN----AGAIKLNDRYCLVARVEGND-----------RKSFFAVAESD---K--GTEGFR--F-RQYPVCLPALTDDE------T-----N-----------------VYDMRLTQ----HEDGWIYGVFCVE---------KSA-G------TA---DLSE-AVASA--GIAR-TKDLTNWERL-P-D----LVTLRSPQQRN-----VTL--LPEFV----D------GKY----AFYTRPMDG-FIETGSGGGIGFG---------LA---DDITHAV------I---D------------E-E-R-MT--SIRRYH-TITE-SKNGAGA---------------TP------IKTERG---WLN----IAHGVR-NT----A---AGLR---------------------------YVIYCFVTDL----S------------------------EP-WKV-IAEPGGYLIAPFKDE---RVGDVSN--VVFTNGAIVDDNG-DVYIYYASSDTR---------LHVAVSS-------------------------------------------IDKLLDYAFN-------TPADAL-RT-AECVKQRCDLIKRNIELL
18 Fugue 47.7219% - - C- - - 3PV2 - ? A:[6-439] --------------------------------------------------------------------------------------------MPSMAPVLK---NIMPAIV-NVAVQGYL----PNRKFES------IGSGVIID----------PNN-GVIITNDHVI---RN------ASLITVTLQDG------------RRLKARLIGGDSETDLAVLKIDA---KNLKS-LVIGDSDKLEV-GDFVVAIGN--PFGLSQ--SATFGIVSALK---NFIQTDAAI--NPGNSGGALVNA----------------------------------KGELIGIN----TAI--------------------LV-GIGFAI-P----------------INMV-KDVAQQIIKF-G-S----IHRGLM-GIFV-----QH---------------------------LTPELAQA-MGYPEDFQGALVS---------QVNPNSPAELAGLKAGDII---T-Q--I-N-----D-T-K-IT--QATQVKTTISL-LRVGSTV---------------KIIVERD-----NK---PLT----LSAVVT-DI----K---SHEQ---------------------------KLQSN------------------------------------------NPFLYGLALRAFEQ---ESPPHG----NVIGVQVVGASE-NSAGWRAGIR-P---------GDIIISA------------------------------NKKPVTDVKSLQTIAQEKKKELLVQ---VLRGPGSMYLL-VI----------------
4 HHSearch 44.1012% 14 - C6 - - 3D37 - ? A:[148-319] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GET-VWQAL--THIA-NSVGLHPWLEPD-G----TLVVGGADYSS-----PPVATLCWSRTDSRC------NIE----RM--DIEWD---TDNRFSEVTFL---------AQ---SHG-----------HDLK-W--V-Y-----K-D-PTMT--LHRPKTVVVS---DNLAAL---------------QKQAKKQLADWRLE---GFT----LTITVG-GHKTRDG---VLWQ---------------------------PGLRVHVIDD----EH----------------------GID-AVF-FLMGR--------------------------------------------------------------------------------------------------------------------------------------------------------
6 HHSearch 36.3314% 40 - C6 - - 1WRU - BP44_BPMU A:[146-317] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SET-VYEAL--VRAS-RARGVLMTSN-AAG----ELVFSRAASTA-----TDE--LVLG-----E------NLL----TL--DFEED---FRDRFSEYTVK---------------------------------------SRKGTA-T-D-SDVTRYRPMIIIADS-KITAKDA---------------QARALREQRRRLAK---SIT----FEAEID-GWTRKDG---QLWM---------------------------PNLLVTIDAS----KY----------------------AIKTTEL-LVSKV--------------------------------------------------------------------------------------------------------------------------------------------------------
5 HHSearch 35.3112% 23 - C6 - - 3D37 - ? B:[148-319] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GET-VWQAL--THIA-NSVGLHPWLEPD-G----TLVVGGADYSS-----PPVATLCWSRTDSRC------NIE----RM--DIEWD---TDNRFSEVTFL----------------------------L--K-W--V-Y-----K-D-PTMT--LHRPKTVVV----DNLAAL---------------QKQAKKQLADWRLE---GFT----LTITVG-GHKTRDG---VLWQ---------------------------PGLRVHVIDD----EH----------------------GID-AVF-FLMGR--------------------------------------------------------------------------------------------------------------------------------------------------------
9 HHSearch 34.723% -21 - C6 - - 4UHV - ? A:[142-306] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----PTLGHRERDH----FFDWQMA-----REVQPGSLTLN---------DY---DFQRPGA------R---LEV--R-S-----NIARP-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-VR---------GIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 HHSearch 33.393% -22 - C6 - - 4UHV - ? B:[142-307] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----PTLGHRERDH----FFDWQMA-----REVQPGSLTLN---------DY---DFQRPGA------R---LEV--R-S-----NIARP-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-VR---------GIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 HHSearch 28.704% -0 - C6 - - 4MTK - ? B:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12 HHSearch 27.964% -0 - C6 - - 4MTK - ? A:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16 HHSearch 26.564% -4 - C6 - - 4MTK - ? D:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15 HHSearch 26.154% 1 - C6 - - 4MTK - ? E:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 HHSearch 25.724% -1 - C6 - - 4MTK - ? F:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 Fugue 25.5617% 33 * C5 * - 5FFL CLM1_MOUSE A:[1-113] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----E-D-P-VT--GPEEVSGQEQG-SLTVQCR---------------YTSGWKDYKKYWCQGVPQRS----CKTLVETDA----S---EQLV---------------------------KKNRVSIRDNQRDFIF----------------------TVT-MED-LRMSDAGIYWCGITK---G----GL--DPMFKVTVNIGPV-PT------------------------------------------------------------------------------------------------------------------
14 HHSearch 24.424% -2 * C6 * - 4MTK - ? C:[142-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EYCV-QY----RET-SFDFI--SRLM-EQEGIYYWFR-H-EQKRHILVLSDAYGAHRSPGGYAS--VPYYP----P------TLGHRERDHFFDWQM---AREVQPGSLTLN---------DY---DFQRPGA------R---LEVRSN-I-----A-R-P-HA--AADYPLYDYPGEYVQSQDG---------------EQYARNRIEAIQAQ---HER----VRLRGV-V---------RGIG---------------------------AGHLFRLSGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 19.2026% 43 - C1 - - 4G5E - ? A:[72-145] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGH----Y------DKE----QLRRKRKYH-ETIMREMAGASFP---------RT---PDVNN--------------Y--V-L-----Q-T-Y-ID--DPSPWETQTIG-AEGKVKA---------------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------