@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTM6: (2017-12-14 )
MSMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHKIIGIDSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDVNLVLFVIDAHKWTQNDDLVLDKLKNADMPVILVINKADTFGDKREILPLIQERAKLMNFAEIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEELPYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIGMDARKDMEKMFEQKIMLTLWVKVKGGWSDDERALKSLGYSDI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80..-.-.....90........-100........110.......120.......-130.-.......140-...--....150.......160-........170-......-.180.......190.......200.......210....-...220.......230.........240.......250.....--..260.......270.......280.......290.......300.......310.......320.......330.......340
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSMHSDQINPDSNENQ
D
P
N
N
L
I
D
Q
F
F
SSKGVTI
P
S
DFKS
G
F
V
A
I
VGRPNV
G
K
S
T
L
M
N
H
L
LGQKLSITSRKPQTTR
H
K
I
I
GIDS-R-
E
K
M
Q
A
V
Y
VDTPGM
H
K
-
K
-
E
V
R
A
I
N
K
M
M
N
R
A
A
H
S
A
LRD
V
N
L
V
L
F
V
I
DA-HK-W-TQND
D
L
V
L
D
K
-LKN--ADM
P
V
I
L
V
I
NKADTFG--
D
K
R
E
I
L
P
L
I
Q
E
-
R
A
K
L
M
N
-
F
A
E
IVP
V
S
A
LRGA
N
L
E
H
L
S
E
T
I
E
K
YLPYQPPLY
S
F
D
Q
I-T
D
R
S
E
R
F
L
A
S
E
I
I
R
--
E
K
I
M
R
Q
L
G
E
ELPY
D
L
T
V
Q
I
ESFKTEEA--TVNEKTGRLKP
A
C
T
Y
I
D
A
T
I
F
V
DRPG
Q
K
A
I
V
IGEKG
A
K
L
K
TIGM
D
A
R
K
D
M
E
K
M
F
EQ
K
I
M
L
T
L
W
V
K
V
KGGWS
D
D
E
R
A
L
K
SLGYSDI
3
PsiBlast_PDB
89.73
56%
-136
- C2 -
-
3IEU
2
ERA_ECOLI
A:
[8-296]
--------------------------------------
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-------
N
E
R
G
G
------
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
21
PsiBlast_CBE
89.44
56%
-136
- C2 -
-
3IEU
1
ERA_ECOLI
B:
[8-296]
--------------------------------------
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-------
N
E
R
G
G
------
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
57
HHSearch
88.35
57%
-130
- C2 -
-
1EGA
-
ERA_ECOLI
B:
[4-296]
----------------------------------
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
N
E
-------------
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
G
----
1
PsiBlast_PDB
87.83
56%
-140
- C2 -
-
1EGA
-
ERA_ECOLI
A:
[8-295]
--------------------------------------
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-------
N
E
R
G
G
------
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
58
HHSearch
81.07
57%
-
- C2 -
-
1X18
2
ERA_THET8
X:
[3-290]
------------------------------------
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
N
E
-------------
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
-------
2
PsiBlast_PDB
80.78
56%
-
- C2 -
-
1X1L
-
ERA_THET8
X:
[8-294]
--------------------------------------
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-------
N
E
R
G
G
------
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
------
4
PsiBlast_PDB
80.16
55%
-
- C2 -
-
1X18
2
ERA_THET8
X:
[5-291]
--------------------------------------
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
-------
N
E
R
G
G
------
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
------
6
PsiBlast_PDB
73.14
41%
20
- C2 -
-
3R9W
3
ERA_AQUAE
A:
[7-306]
------------------------------------
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
-
K
S
D
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
-
T
E
G
W
-
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
--
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
--
N
---------
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
--
81
Fugue
72.84
51%
-157
- C2 -
-
1EGA
-
ERA_ECOLI
A:
[4-182]
----------------------------------
D
K
S
Y
C
G
F
I
A
I
V
G
R
P
N
V
G
K
S
T
L
L
N
K
L
L
G
Q
K
I
S
I
T
S
R
K
A
Q
T
T
R
H
R
I
V
G
I
H
T
-
E
-
G
A
Y
Q
A
I
Y
V
D
T
P
G
L
H
M
-
E
-
E
K
R
A
I
N
R
L
M
N
K
A
A
S
S
S
I
G
D
V
E
L
V
I
F
V
V
E
G
-
T
R
-
W
-
T
P
D
D
E
M
V
L
N
K
-
L
R
E
--
G
K
A
P
V
I
L
A
V
N
K
V
D
N
V
Q
--
E
K
A
D
L
L
P
H
L
Q
F
-
L
A
S
Q
M
N
-
F
L
D
I
V
P
I
S
A
E
T
G
L
N
V
D
T
I
A
A
I
V
R
K
H
L
P
E
A
T
H
H
F
P
E
--------------------------------------------------------------------------------------------------------------------------------------
59
HHSearch
72.83
41%
-11
- C2 -
-
1WF3
3
ERA_THET8
A:
[3-298]
----------------------------------
E
K
T
Y
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
H
K
-
P
--
M
D
A
L
G
E
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
-
R
H
-
P
P
T
P
E
D
E
L
V
A
R
A
-
L
K
P
LV
G
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
--
Y
P
E
E
A
M
K
---
A
-
Y
H
E
L
L
P
-
E
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
--
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
R
E
-------------
N
G
V
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
R
S
-
5
PsiBlast_PDB
72.73
41%
22
- C2 -
-
3IEV
2
ERA_AQUAE
A:
[8-307]
------------------------------------
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
-
K
S
D
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
-
T
E
G
W
-
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
--
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
--
N
---------
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
--
60
HHSearch
72.35
42%
22
- C2 -
-
3IEV
2
ERA_AQUAE
A:
[7-307]
-----------------------------------
H
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
-
I
P
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
-
P
K
K
S
D
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
-
T
E
-
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
--
P
A
K
N
V
L
P
L
I
D
E
-
I
H
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
--
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
-----------
N
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
--
7
PsiBlast_PDB
71.75
41%
25
- C2 -
-
3R9X
3
ERA_AQUAE
A:
[7-306]
------------------------------------
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
I
P
-
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
-
K
S
D
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
-
T
E
G
W
-
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
--
P
A
K
N
V
L
P
L
I
D
E
I
H
K
K
H
P
E
-
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
--
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
--
N
---------
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
--
61
HHSearch
71.70
43%
24
- C2 -
-
3R9X
3
ERA_AQUAE
A:
[6-306]
-----------------------------------
H
M
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
G
V
K
N
-
I
P
N
E
A
Q
I
I
F
L
D
T
P
G
I
Y
E
-
P
K
K
S
D
V
L
G
H
S
M
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
M
I
D
A
-
T
E
-
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
P
--
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
--
P
A
K
N
V
L
P
L
I
D
E
-
I
H
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
-
T
D
L
P
L
R
L
L
A
A
E
I
V
R
--
E
K
A
M
M
L
T
R
E
E
V
P
T
S
I
A
V
K
I
N
E
I
K
P
G
D
A
-----------
N
P
N
M
L
V
I
K
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
P
V
Y
L
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
R
L
F
G
Y
A
--
8
PsiBlast_PDB
71.24
40%
-19
- C2 -
-
1WF3
3
ERA_THET8
A:
[7-296]
--------------------------------------
S
G
F
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
V
K
V
A
P
I
S
P
R
P
Q
T
T
R
K
R
L
R
G
I
L
T
-
E
-
G
R
R
Q
I
V
F
V
D
T
P
G
L
H
K
-
P
--
M
D
A
L
G
E
F
M
D
Q
E
V
Y
E
A
L
A
D
V
N
A
V
V
W
V
V
D
L
R
H
P
-
P
-
T
P
E
D
E
L
V
A
R
A
-
L
K
P
LV
G
K
V
P
I
L
L
V
G
N
K
L
D
A
A
K
--
Y
P
E
E
A
M
K
A
Y
H
E
----
L
L
P
-
E
A
E
P
R
M
L
S
A
L
D
E
R
Q
V
A
E
L
K
A
D
L
L
A
L
M
P
E
G
P
F
F
Y
P
E
D
Y
A
K
S
D
Q
T
F
G
E
W
V
A
E
I
L
R
--
E
E
A
M
K
R
L
W
H
E
V
P
Y
A
V
A
T
K
V
E
E
V
A
E
R
E
N
--
G
V
-----------
L
Y
I
K
A
I
L
Y
V
E
R
P
S
Q
K
A
I
V
I
G
E
G
G
R
K
I
K
E
I
G
Q
A
T
R
K
Q
L
E
A
L
L
G
K
K
V
Y
L
D
L
E
V
K
V
Y
P
D
W
R
K
D
P
E
A
L
R
E
L
G
Y
---
20
PsiBlast_PDB
52.43
27%
-105
- C2 -
-
4DCV
-
DER_BACSU
A:
[26-193]
-----------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
---------
P
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
-
R
E
-
G
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
K
K
P
V
V
L
A
V
N
K
L
-----------
Y
D
F
Y
S
------
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
K
N
I
P
-------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
51.05
27%
-98
- C2 -
-
4DCS
-
DER_BACSU
A:
[26-193]
-----------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
---------
P
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
-
R
E
-
G
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
K
K
P
V
V
L
A
V
N
K
L
------
M
R
A
N
I
Y
D
F
Y
S
------
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
K
N
I
P
-------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
50.97
27%
-106
- C2 -
-
4DCU
1
DER_BACSU
A:
[26-193]
-----------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
R
I
S
-----------
R
I
Y
S
S
A
E
-
W
-
L
N
Y
D
F
N
L
I
D
T
G
G
---------
P
F
L
A
Q
I
R
Q
Q
A
E
I
A
M
D
E
A
D
V
I
I
F
M
V
N
G
-
R
E
-
G
V
T
A
A
D
E
E
V
A
K
I
-
L
Y
R
--
T
K
K
P
V
V
L
A
V
N
K
L
-----------
Y
D
F
Y
S
------
L
G
-
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
A
E
H
F
K
N
I
P
-------------------------------------------------------------------------------------------------------------------------------------------
82
Fugue
49.34
64%
-136
- C2 -
-
1EGA
-
ERA_ECOLI
A:
[183-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
I
-
T
D
R
S
Q
R
F
M
A
S
E
I
I
R
--
E
K
L
M
R
F
L
G
A
E
L
P
Y
S
V
T
V
E
I
E
R
F
V
S
N
E
-------------
R
G
G
Y
D
I
N
G
L
I
L
V
E
R
E
G
Q
K
K
M
V
I
G
N
K
G
A
K
I
K
T
I
G
I
E
A
R
K
D
M
Q
E
M
F
E
A
P
V
H
L
E
L
W
V
K
V
K
S
G
W
A
D
D
E
R
A
L
R
S
L
-----
16
PsiBlast_PDB
48.73
29%
-53
- C2 -
-
1XZP
-
MNME_THEMA
A:
[246-464]
-----------------------------------------
M
V
I
V
G
K
P
N
V
G
K
S
T
L
L
N
R
L
L
N
E
D
R
A
I
V
T
D
I
P
G
T
T
R
D
V
I
S
E
E
I
V
-
I
-
R
G
I
L
F
R
I
V
D
T
A
G
V
R
S
-
E
-
T
N
D
L
V
E
R
L
G
I
E
R
T
L
Q
E
I
E
K
A
D
I
V
L
F
V
L
D
A
-
S
S
P
L
-
D
E
E
D
R
K
I
L
E
R
-
I
K
N
--
K
R
Y
--
L
V
V
I
N
K
V
D
V
V
E
KI
N
E
E
E
I
-------
K
N
K
L
G
T
-
D
R
H
M
V
K
I
S
A
L
K
G
E
G
L
E
K
L
E
E
S
I
Y
R
E
T
Q
E
I
F
E
R
G
S
D
S
L
I
-
T
N
L
R
Q
K
Q
L
L
E
N
V
K
G
H
L
E
D
A
I
K
S
L
K
E
G
M
P
V
D
M
A
----
S
I
D
L
E
R
A
L
N
L
L
D
E
V
T
G
R
-----------------------------------------------------------------------------