@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTQ7: (2017-12-14 )
MAFPHHTEHHAIQRSGWLRASVLGANDGIISVTSLIMGMAASGASSHTLFITCVAGLISGATSMAAGEYISVKSQEDIEKSDLAIEAKELKKYPQKELDELTQIYISRGLSKELAKEVAIQLTTHDALGAHARDEIGIHENTAANPIQAALSSAASFSFGAFFPMLAILFSPEHLIMPSVLITGIAALAILGALSSYFAGTSKIKGSLRITLWGILAMAFSSWIGSLFNVTPL
Atome Classification :
(20 SA)
-------------------------------------------------------------------------......----...10..---......20........30........40.....---...50........60......---..70........80........90.---.....--..100.......110....-...120.......------------130.-----.---.....140-----.........150....----...160--------------..--.....170...--------.-------...180--....--..-------.--..190.-......200.-......210.-...---....220.......230.------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------MAFPHH----T
E
H
H
A
I
Q---RSG
W
L
R
A
S
V
LGAND
G
I
I
S
V
T
S
L
I
M
G
M
AASGASS---
H
T
L
F
I
T
C
V
A
G
L
ISG
A
T
SMAAG---
E
Y
I
S
VKSQEDIEKSD
L
A
I
E
A
K
E
L
K
K---Y
P
Q
K
E
--
L
D
E
L
T
Q
I
Y
I
SRG
L
S
K
E
L
A
K
-
E
V
A
I
Q
L
TTHDALG------------AHAR-----D---EIGIHE-------NTAA
N
P
I
Q
A
A
L
S
S
AAS----FS
F
G
A
F
--------------
F
P
--
M
L
A
I
L
FSP
E
H
L
--------
I
-------
M
P
S
V
----
L
I
T
G
--
I
A
-------
A
--
L
A
I
L
G
A
-
L
S
S
Y
FAGTSK-IKG
S
L
R
I
T
-
L
-
W
G
I
---
L
A
M
A
F
S
S
W
I
G
S
L
FNVTPL------------------------------------------------------------------------------
23
Fugue
66.14
19%
-90
- C3 -
-
5FUB
6
?
A:
[1-337]
-------------------------------------------------------------------------
G
D
A
W
Q
D
----
D
E
Y
F
G
N
Y
---
G
T
L
R
L
H
L
E
M
L
S
D
K
P
R
T
E
T
Y
R
Q
V
I
L
S
N
S
A
A
L
R
E
K
---
V
V
L
D
L
G
C
G
T
G
V
I
S
L
F
C
A
L
L
A
-------
K
P
A
G
V
Y
A
V
E
A
S
S
M
A
E
H
T
E
E
L
V
K
---
Q
--
N
G
--
C
D
G
V
V
T
V
F
Q
E
R
A
E
N
L
T
L
P
T
-
K
V
D
V
L
V
S
--
E
W
M
G
NCLLFEYM
L
E
S
V
L
L
A
R
-----
D
---
R
W
-
L
K
K
-------
G
G
M
M
W
P
S
S
A
C
L
T
I
V
P
C
----
Q
A
F
S
D
Y
R
Q
K
VEFWENPYGLN
F
S
--
Y
L
Q
S
L
A
Q
K
E
F
L
S
K
P
K
F
S
H
H
L
-------
Q
P
E
D
----
C
L
S
T
--
P
A
-------
D
--
V
I
T
L
D
M
-
V
T
I
Q
V
S
D
L
E
R
-
L
K
G
E
F
T
F
T
-
V
E
K
S
G
---
M
F
H
G
F
T
V
W
F
S
A
H
F
Q
C
L
E
E
D
G
P
S
I
E
L
N
TGPYSEITHWK
Q
T
L
F
M
L
D
A
P
V
S
V
E
EG
D
I
I
A
G
S
I
R
L
Q
R
NPIWRR
H
L
S
I
T
F
L
W
N
I
NSTEVST
V
K
T
K
C
F
P
MWR
25
Fugue
64.40
21%
-31
- C2 -
-
4ZMU
-
?
A:
[5-345]
MLA
C
P
L
P
PD
E
A
L
R
Q
Q
A
L
D
D
M
ALVDTPAE
H
Y
L
D
A
L
V
E
L
A
R
E
T
F
GVKTVLISLIDHD
R
Q
W
F
KARIGLDAEQTPRD
L
S
F
C
G
H
A
I
LA
S
E
P
L
M
V
T
DAS
R
D
P
R
F
H
D
N
P
L
V
T
G
P
P
F
I
R
F
Y
A
G
E
P
L
H
A
S
N
G
Q
A
I
---
G
T
L
C
L
I
D
P
S
P
R
L
L
D
L
R
E
G
R
Q
L
---
N
R
L
S
I
L
A
E
G
Y
L
Q
L
R
S
L
T
E
H
T
R
F
L
R
Q
EID
R
E
Q
R
K
SL
L
D
P
L
T
Q
L
W
N
R
A
G
F
H
A
L
H
Q
H
-
E
L
E
L
A
R
A
S
D
Q
R
I
G
------------
I
I
Y
S
-----
D
I
D
H
F
K
R
I
N
D
-------
T
L
G
H
R
A
G
D
S
V
L
R
E
A
A
S
----
R
L
R
A
A
L
--------------
R
P
E
D
L
L
A
R
F
G
G
E
E
F
V
--------
A
-------
M
V
R
V
RE
T
T
E
L
T
M
--
I
A
-------
N
R
I
R
E
L
M
E
A
-
T
P
I
D
C
A
G
T
S
V
P
V
T
I
S
A
G
C
T
-
L
-
A
G
S
GEE
P
E
R
A
L
A
R
A
D
A
A
L
Y
D
A
K
R
A
GRN
R
V
V
S
V----------------------------------------------------------------------
20
Fugue
63.79
15%
58
- C1 -
-
4EGD
-
Y2783_STAA8
A:
[27-253]
-----------------------------------------------------------G
R
N
A
Q
I
K
D
T
F
N
Q
T
L
K
L
Y
P
T
K
----
N
L
D
D
F
Y
D
---
K
E
G
F
R
D
Q
E
F
K
K
G
D
K
G
T
W
I
V
N
S
E
M
V
I
E
P
----
K
G
---
K
D
M
E
T
R
G
M
V
L
Y
I
N
R
N
T
R
T
T
K
G
---
Y
Y
F
I
S
E
M
T
P
K
D
D
E
K
R
Y
P
V
K
M
E
H
N
K
I
---
I
P
T
K
P
--
L
P
-------
N
D
K
L
K
K
E
I
E
N
F
K
F
F
V
Q
Y
G
N
F
K
D
I
N
------------
D
Y
K
D
-----
G
---
D
I
S
Y
N
P
-------
N
V
P
S
Y
S
A
K
Y
Q
L
N
N
D
---------
D
Y
N
--------------
V
Q
--
Q
L
R
K
R
Y
D
I
P
T
K
--------
Q
-------
A
P
K
L
----
L
L
K
G
--
D
G
-------
D
--
L
K
-----------
G
S
S
V
-
G
S
R
S
L
E
F
T
-
F
-
V
E
-----
N
K
E
E
N
I
Y
F
T
D
S
V
Q
Y
T
P
S
E-----------------------------------------------------------------------------
8
PsiBlast_PDB
57.58
30%
-88
- C4 -
-
3B9W
-
?
A:
[147-256]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
------------
A
Y
F
G
-----
L
---
G
V
S
I
A
L
-------
T
T
A
A
Q
R
A
Q
P
I
E
S
D
A
T
S
----
D
R
F
S
M
L
--------------
G
S
--
M
V
L
W
L
F
W
P
S
F
A
--------
T
A
IVPFEQ
M
P
Q
T
----
I
V
N
T
--
L
-----------
L
A
L
C
G
A
T
L
A
T
Y
F
L
S
A
L
F
-
H
K
G
K
A
S
I
V
-
D
-
M
A
N
---
A
A
L
A
G
G
V
A
I
G
S
V
C
N
I
---------------------------------------------------------------------------------
6
PsiBlast_PDB
57.43
30%
-84
- C4 -
-
3B9Z
2
?
A:
[141-250]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
------------
A
Y
F
G
-----
L
---
G
V
S
I
A
L
-------
T
T
A
A
Q
R
A
Q
P
I
E
S
D
A
T
S
----
D
R
F
S
M
L
--------------
G
S
--
M
V
L
W
L
F
W
P
S
F
A
--------
T
A
IVPFEQ
M
P
Q
T
----
I
V
N
T
--
L
-----------
L
A
L
C
G
A
T
L
A
T
Y
F
L
S
A
L
F
-
H
K
G
K
A
S
I
V
-
D
-
M
A
N
---
A
A
L
A
G
G
V
A
I
G
S
V
C
N
I
---------------------------------------------------------------------------------
5
PsiBlast_PDB
57.17
30%
-86
- C4 -
-
3B9Y
1
?
A:
[141-250]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
------------
A
Y
F
G
-----
L
---
G
V
S
I
A
L
-------
T
T
A
A
Q
R
A
Q
P
I
E
S
D
A
T
S
----
D
R
F
S
M
L
--------------
G
S
--
M
V
L
W
L
F
W
P
S
F
A
--------
T
A
IVPFEQ
M
P
Q
T
----
I
V
N
T
--
L
-----------
L
A
L
C
G
A
T
L
A
T
Y
F
L
S
A
L
F
-
H
K
G
K
A
S
I
V
-
D
-
M
A
N
---
A
A
L
A
G
G
V
A
I
G
S
V
C
N
I
---------------------------------------------------------------------------------
7
PsiBlast_PDB
56.87
30%
-77
- C4 -
-
3BHS
-
?
A:
[147-256]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
------------
A
Y
F
G
-----
L
---
G
V
S
I
A
L
-------
T
T
A
A
Q
R
A
Q
P
I
E
S
D
A
T
S
----
D
R
F
S
M
L
--------------
G
S
--
M
V
L
W
L
F
W
P
S
F
A
--------
T
A
IVPFEQ
M
P
Q
T
----
I
V
N
T
--
L
-----------
L
A
L
C
G
A
T
L
A
T
Y
F
L
S
A
L
F
-
H
K
G
K
A
S
I
V
-
D
-
M
A
N
---
A
A
L
A
G
G
V
A
I
G
S
V
C
N
I
---------------------------------------------------------------------------------
21
Fugue
56.48
14%
-15
- C3 -
-
4K6L
2
?
G:
[1-224]
----------------------------------------------------------------------VDF
V
Y
R
V
D
S
----
T
P
P
D
V
I
F
---
R
D
G
F
---
S
L
L
G
Y
N
R
---
N
F
Q
Q
F
I
S
G
R
S
C
S
G
G
S
S
---
D
S
R
Y
I
A
T
T
S
S
-
V
N
Q
T
Y
A
I
A
R
A
---
Y
Y
S
R
S
T
F
K
G
N
L
Y
R
Y
Q
I
R
A
D
N
N
F
Y
S
L
---
L
P
S
I
T
--
Y
L
E
T
Q
G
G
H
F
N
-
A
Y
E
K
T
M
M
R
-
L
Q
R
E
Y
V
S
T
L
S
I
L
P
------------
E
N
I
Q
-----
K
---
A
V
A
L
V
Y
-------
D
S
A
T
G
L
V
K
D
G
V
S
T
M
N
A
SYLG
L
S
T
T
S
N
--------------
P
G
--
V
I
P
F
L
P
E
P
Q
T
Y
--------
T
-------
Q
Q
R
I
----
D
A
F
G
PL
I
S
-------
S
--
C
F
S
I
G
S
-
V
C
H
S
H
R
G
Q
R
A
-
D
V
Y
N
M
S
F
Y
D
A
-
R
P
V
---
I
E
L
I
L
S
K
-----------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.07
27%
-58
- C4 -
-
5G4J
1
?
A:
[156-274]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
T
T
G
L
T
V
H
E
P
L
G
------------
A
H
V
R
A
L
RIP
D
---
V
S
G
I
A
E
VD
V
P
V
L
L
E
Q
S
L
A
D
V
D
A
A
I
A
S
L
Q
A
----
A
G
H
G
V
S
--------------
V
F
--
L
F
D
P
L
F
S
T
E
G
L
--------
L
Q
------
L
P
S
G
----
Y
I
E
G
--
V
A
T
R
V
R
A
A
G
G
--
L
V
I
S
D
E
-
V
Q
S
G
F
G
R
T
G
S
--------
G
-
M
-
W
G
Y
-------------
Q
M
F
N
V
E
P
-------------------------------------------------------------------------------
1
PsiBlast_PDB
52.87
27%
-64
- C4 -
-
5G4I
1
?
A:
[156-274]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
T
T
G
L
T
V
H
E
P
L
G
------------
A
H
V
R
A
L
RIP
D
---
V
S
G
I
A
E
VD
V
P
V
L
L
E
Q
S
L
A
D
V
D
A
A
I
A
S
L
Q
A
----
A
G
H
G
V
S
--------------
V
F
--
L
F
D
P
L
F
S
T
E
G
L
--------
L
Q
------
L
P
S
G
----
Y
I
E
G
--
V
A
T
R
V
R
A
A
G
G
--
L
V
I
S
D
E
-
V
Q
S
G
F
G
R
T
G
S
--------
G
-
M
-
W
G
Y
-------------
Q
M
F
N
V
E
P
-------------------------------------------------------------------------------
17
HHSearch
48.65
24%
-189
- C4 -
-
2BZB
-
?
B:
[6-39]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
N
---
K
I
E
N
K
--
K
K
E
L
I
Q
L
V
A
R
H
G
L
D
H
D
K
V
L
-
L
F
S
R
D
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
42.73
24%
-124
- C4 -
-
5J73
-
?
D:
[7-56]
-----------------------------------------------------------------------------------------------------------------------------------------------------
S
---
D
Y
I
I
E
Q
I
Q
R
D
Q
E
E
A
R
K
K
V
E
E
----------
A
E
E
--
R
L
E
R
V
K
E
A
S
K
R
G
V
S
S
D
Q
L
L
-
D
L
I
R
E
L
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
41.91
24%
-119
- C4 -
-
5J73
-
?
A:
[6-56]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
S
---
D
Y
I
I
E
Q
I
Q
R
D
Q
E
E
A
R
K
K
V
E
E
----------
A
E
E
--
R
L
E
R
V
K
E
A
S
K
R
G
V
S
S
D
Q
L
L
-
D
L
I
R
E
L
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
39.56
20%
-31
- C4 -
-
5F5S
-
B:
[6-58]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
D
E
E
E
---
Y
E
A
W
K
--
V
R
E
L
K
R
I
K
R
D
R
E
D
R
E
A
L
E
K
-
E
K
A
E
I
E
R
M
R
N
L
T
E
------------
E
E
R
R
-----
A
---
E
L
R
A
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
37.73
21%
-41
- C4 -
-
5B52
-
?
A:
[4-60]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
E
F
A
A
A
E
K
---
A
L
Q
E
Q
--
M
A
Q
L
E
A
L
K
K
D
A
G
L
K
R
E
I
E
F
-
E
Q
K
L
V
G
L
M
K
S
-
Y
D
------------
K
S
L
R
-----
D
---
I
I
A
I
L
D
-------
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
35.26
27%
-71
- C4 -
-
3PIH
1
UVRA_THEMA
A:
[615-684]
-------------------------------------------------------------------------------------------------------------------
V
T
G
V
S
G
S
G
K
S
S
LVM
E
T
L
Y
P
A
L
M
N
L
L
--
H
K
T
K
L
P
A
G
---
E
F
D
S
I
E
G
H
E
N
I
D
K
M
-
I
A
I
D
Q
S
P
I
G
R
---
T
P
R
S
N
--
P
A
T
Y
T
K
V
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
34.34
18%
23
- C4 -
-
5IP0
-
?
A:
[3-109]
---------------------------------------------------------------------------------------------------------
M
D
V
I
K
S
F
T
E
Q
M
Q
G
F
A
A
P
L
T
R
Y
---
N
Q
L
L
A
S
N
I
E
Q
L
T
--
R
L
Q
L
A
S
A
---
N
A
Y
A
E
L
G
L
N
Q
L
Q
A
V
S
K
V
Q
D
T
Q
S
L
A
A
---
L
G
T
V
Q
--
L
E
T
A
S
Q
L
--
S
R
Q
M
L
D
D
I
Q
K
-
L
S
A
L
G
Q
Q
F
K
E
E
L
D
------------
V
L
T
A
-----
D
---
G
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
33.68
14%
33
* C3 *
-
2KPO
-
?
A:
[1-110]
---------------------------------------------------------------------------------------------------------------------------
M
L
L
---
Y
V
L
I
I
S
N
D
K
K
L
I
E
E
A
R
K
M
A
E
K
A
N
L
E
L
R
T
V
K
T
E
D
E
L
K
K
Y
L
E
E
F
R
K
E
S
Q
N
I
---
K
V
L
I
L
--
V
S
N
D
E
E
L
D
K
A
K
E
L
A
Q
K
M
E
I
-
D
V
R
T
R
K
V
T
S
P
D
E
A
------------
K
R
W
I
-----
K
---
E
F
S
E
E
G
-------
G
S
L
E
H
H
H
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
33.56
12%
80
* C4 *
-
4YV4
-
SAS5_CAEEL
A:
[7-53]
------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
N
W
R
D
A
M
K
T
E
L
Q
T
I
R
T
E
I
Q
E
---
E
T
A
R
R
--
Q
E
E
L
N
A
Q
N
L
V
K
M
Q
E
L
M
S
N
F
-
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
28.25
26%
0
- C- -
-
4BUJ
-
SKI3_YEAST
B:
[280-397]
-------------------------------------------------------------------------------------------------------------------------------------------
L
V
N
H
Q
S
L
L
A
W
Q
---
K
Y
F
E
W
T
D
Y
E
D
L
D
N
M
D
A
P
L
I
I
K
Y
F
K
K
---
F
P
K
D
P
--
L
A
M
I
L
Y
S
W
L
S
S
K
L
S
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------