@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTY9: (2017-12-15 )
MLHLHVHPENPQQRLIEQAVERIRAGDVVVYPTDAAYAIGCQIGNKNAMERIAQIRGLGPKHQYAIMCCDLSDIATYAKVDNATYRLLKANTPAITTFILPATSEVPRRLMHPKKKTIGLRIPSNPICQALLKELGGPLLTSTLILPGQEDPLDDPYDIENQLAKRIDVFIDGGFGTLTTTSIVDLSGEHPEIIRHGVGDVSAFE
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------.........10.-.-......20........30........40........50.........60......-..70......---.--.---80...-....-.90........100..--.....110.......120........130......-.140.-......150.......160.......170-...---..--.--.--.180.......190.......200...----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------
M
L
H
L
H
VHPE
N
P
Q
-
Q
-
R
L
I
E
Q
A
V
E
R
IRAG
D
V
V
V
YPTDA
A
Y
A
I
G
C
QIG
N
K
N
A
M
E
-
R
I
A
Q
I
RGLGPK
H
Q
Y
A
I
M
-
C
C
D
L
S
D
I
A
T
Y
---
A
--K---VDN
A
T
-
Y
R
L
L
-KANTP
A
I
T
T
F
I
LPA
T
S
--
E
V
P
R
R
L
MHPKK
K
T
I
G
L
-RIPS
N
P
I
C
Q
A
L
L
K
ELGGP-
L
L
T
S
T
-
L
ILPGQEDPLDDPY
D
I
E
N
Q
L
A
K
R
I
D
V
F
I
--DGG---FG--
T
--
L
--
T
T
T
S
I
V
DLSGE
H
P
E
I
I
R
HGVGDVSAFE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
99.02
54%
-119
- C5 -
-
1K7J
-
YCIO_ECOLI
A:
[5-205]
-----------------------------------------------------------------------------------------
F
Y
I
H
P
D
N
P
Q
-
Q
-
R
L
I
N
Q
A
V
E
I
V
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
-
C
R
D
L
S
E
L
S
T
Y
---
S
--
F
---
V
D
N
V
A
-
F
R
L
M
-
K
N
N
T
P
G
N
Y
T
F
I
L
K
G
T
K
--
E
V
P
R
R
L
L
Q
E
K
R
K
T
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
-
L
M
L
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
--
H
G
G
---
Y
L
--
G
--
Q
--
K
P
T
T
V
I
D
L
T
D
D
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
98.27
52%
-123
- C5 -
-
1KK9
-
YCIO_ECOLI
A:
[20-220]
-----------------------------------------------------------------------------------------
F
Y
I
H
P
D
N
P
Q
-
Q
-
R
L
I
N
Q
A
V
E
I
V
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
-
C
R
D
L
S
E
L
S
T
Y
---
S
--
F
---
V
D
N
V
A
-
F
R
L
M
-
K
N
N
T
P
G
N
Y
T
F
I
L
K
G
T
K
--
E
V
P
R
R
L
L
Q
E
K
R
K
T
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
-
L
M
L
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
--
H
G
G
---
Y
L
--
G
--
Q
--
K
P
T
T
V
I
D
L
T
D
D
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.24
52%
-119
- C5 -
-
1K7J
-
YCIO_ECOLI
A:
[5-205]
-----------------------------------------------------------------------------------------
F
Y
I
H
P
D
N
P
Q
-
Q
-
R
L
I
N
Q
A
V
E
I
V
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
-
C
R
D
L
S
E
L
S
T
Y
---
S
--
F
---
V
D
N
V
A
-
F
R
L
M
-
K
N
N
T
P
G
N
Y
T
F
I
L
K
G
T
K
--
E
V
P
R
R
L
L
Q
E
K
R
K
T
I
G
M
-
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
-
M
L
S
T
S
-
L
M
L
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
--
H
G
G
---
Y
L
--
G
--
Q
--
K
P
T
T
V
I
D
L
T
D
D
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
77.19
50%
-6
- C5 -
-
1K7J
-
YCIO_ECOLI
A:
[2-206]
--------------------------------------------------------------------------------------
S
Q
F
F
Y
I
H
P
D
N
P
Q
-
Q
-
R
L
I
N
Q
A
V
E
I
V
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
E
-
R
I
C
R
I
R
Q
-
L
P
D
G
H
N
F
T
L
M
C
R
D
L
S
E
L
S
T
Y
---
S
--
F
---
V
D
N
V
A
-
F
R
L
-
M
K
N
N
T
P
G
N
Y
T
F
I
L
K
G
T
K
--
E
V
P
-
R
R
L
L
Q
E
K
R
K
T
I
G
M
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
M
L
S
T
S
L
M
L
--
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
--
H
G
G
---
Y
L
--
G
--
Q
--
K
P
T
T
V
I
D
L
T
D
D
T
P
V
V
V
R
E
G
V
G
D
V
K
P
F
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
66.77
22%
-102
- C5 -
-
1JCU
-
?
A:
[1-195]
--------------------------------------------------------------------------------------
M
L
I
R
K
I
T
R
K
N
P
S
-
P
-
D
V
L
E
E
A
I
S
V
M
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
C
-
V
S
C
V
D
E
I
P
R
F
---
S
--
R
---
P
S
G
D
A
-
M
E
L
M
-
E
R
I
L
P
G
P
Y
T
V
V
L
E
R
N
E
--
L
I
P
D
V
I
T
G
G
S
S
R
-
V
G
I
-
R
V
P
D
D
E
I
C
R
R
I
A
A
R
F
--
P
-
V
T
A
T
S
-
A
N
I
S
G
K
P
-
P
S
P
R
L
E
E
I
V
R
D
L
D
A
-
V
D
L
V
L
--
D
A
G
---
D
C
L-
D
--
M
--
E
P
S
T
V
I
D
L
T
V
N
P
P
R
V
L
R
R
G
K
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
66.47
22%
-90
- C5 -
-
3TTC
1
?
A:
[109-290]
------------------------------------------------------------------------------------------------
E
Q
-
E
-
A
A
L
Q
A
A
I
A
Q
L
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
M
-
L
P
V
A
D
G
L
P
--------------
D
A
A
-
R
Q
L
L
-
T
T
-
P
A
A
P
I
V
L
V
D
K
K
Y
V
P-
E
L
C
D
D
I
-
A
P
G
L
N
E
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
-
G
N
L
S
G
K
P
P
A
-
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
--
I
H
N
---
R
D
--
I
--
V
Q
R
M
D
D
S
V
V
R
E
S
G
---
E
M
L
R
R
S
R
G
Y
V
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
66.08
22%
-100
- C5 -
-
1JCU
-
?
A:
[1-201]
--------------------------------------------------------------------------------------
M
L
I
R
K
I
T
R
K
N
P
S
-
P
-
D
V
L
E
E
A
I
S
V
M
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
C
-
V
S
C
V
D
E
I
P
R
F
---
S
--
R
---
P
S
G
D
A
-
M
E
L
M
-
E
R
I
L
P
G
P
Y
T
V
V
L
E
R
N
E
--
L
I
P
D
V
I
T
-
G
G
S
S
R
V
G
I
-
R
V
P
D
D
E
I
C
R
R
I
A
A
R
F
--
P
-
V
T
A
T
S
-
A
N
I
S
G
K
P
P
S
-
P
R
L
E
E
I
V
R
D
L
D
-
A
V
D
L
V
L
--
D
A
G
---
D
C
--
L
--
D
M-
E
P
S
T
V
I
D
L
T
V
N
P
P
R
V
L
R
R
G
K
G
P
L
D
P
V
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
66.00
22%
-91
- C5 -
-
3TTD
-
?
A:
[109-290]
------------------------------------------------------------------------------------------------
E
Q
-
E
-
A
A
L
Q
A
A
I
A
Q
L
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
M
-
L
P
V
A
D
G
L
P
D
--------------
A
A
-
R
Q
L
L
-
T
T
-
P
A
A
P
I
V
L
V
D
K
K
Y
V
P-
E
L
C
D
D
I
-
A
P
G
L
N
E
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
-
G
N
L
S
G
K
P
P
A
-
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
--
I
H
N
---
R
D
--
I
--
V
Q
R
M
D
D
S
V
V
R
E
S
G
---
E
M
L
R
R
S
R
G
Y
V
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
65.05
21%
-57
- C5 -
-
1HRU
-
TSAC_ECOLI
B:
[4-183]
-----------------------------------------------------------------------------------------------
N
L
Q
-
R
-
D
A
I
A
A
A
I
D
V
L
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
-
A
A
N
Y
E
Q
L
K
P
Y
---
I
--
D
DTM
L
T
D
V
Q
-
R
E
T
I
-
F
S
R
W
P
G
P
V
T
F
V
F
P
A
P
A
--
T
T
P
R
W
L
T
-
G
R
F
D
S
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
-
A
N
L
S
G
L
P
P
C
-
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
V
V
P
--
G
E
T
---
G
G
--
R
--
L
--
N
P
S
E
I
R
D
A
L
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
63.87
21%
-51
* C5 *
-
1HRU
-
TSAC_ECOLI
A:
[3-188]
----------------------------------------------------------------------------------------------
N
N
L
Q
-
R
-
D
A
I
A
A
A
I
D
V
L
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
-
M
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
-
A
A
N
Y
E
Q
L
K
P
Y
---
I
DD
T
M--
L
T
D
V
Q
-
R
E
T
I
-
F
S
R
W
P
G
P
V
T
F
V
F
P
A
P
A
--
T
T
P
R
W
L
T
G
-
R
F
D
S
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
-
A
N
L
S
G
L
P
-
P
C
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
V
V
P
--
G
E
T
---
G
G
--
R
--
L
--
N
P
S
E
I
R
D
A
L
T
G
--
E
L
F
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
63.30
19%
-54
- C5 -
-
4G9I
-
?
B:
[199-389]
-------------------------------------------------------------------------------------------------
Y
-
G
-
D
P
L
R
K
A
A
E
L
I
D
K
G
Y
I
V
A
I
K
G
I
G
G
I
H
L
A
C
D
A
A
N
E
E
V
V
A
-
E
L
R
R
R
T
F
R
P
-
Q
K
P
F
A
I
M
-
A
K
D
I
E
T
V
K
S
F
---
A
--
Y
---
V
S
P
E
E
-
E
E
E
L
-
T
S
-
Y
R
R
P
I
-
I
T
L
R
K
K
E
PF
P
L
P
E
N
L
-
A
P
G
L
H
T
I
G
V
-
M
L
P
Y
A
G
T
H
Y
I
L
F
H
W
S
K
T
P
V
Y
V
M
T
S
-
A
N
Y
P
G
M
P
M
V
-
K
D
N
E
R
A
F
E
E
L
K
D
V
A
D
Y
F
L
--
L
H
N
---
R
K
--
I
L
N
R
--
A
D
D
S
V
I
R
F
V
D
G
K
R
A
V
I
R
R
S
R
G
F
V
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
63.07
19%
-64
- C5 -
-
4G9I
-
?
A:
[199-389]
-------------------------------------------------------------------------------------------------
Y
-
G
-
D
P
L
R
K
A
A
E
L
I
D
K
G
Y
I
V
A
I
K
G
I
G
G
I
H
L
A
C
D
A
A
N
E
E
V
V
A
-
E
L
R
R
R
T
F
R
P
-
Q
K
P
F
A
I
M
-
A
K
D
I
E
T
V
K
S
F
---
A
--
Y
---
V
S
P
E
E
-
E
E
E
L
-
T
S
-
Y
R
R
P
I
-
I
T
L
R
K
K
E
PF
P
L
P
E
N
L
-
A
P
G
L
H
T
I
G
V
-
M
L
P
Y
A
G
T
H
Y
I
L
F
H
W
S
K
T
P
V
Y
V
M
T
S
-
A
N
Y
P
G
M
P
M
V
-
K
D
N
E
R
A
F
E
E
L
K
D
V
A
D
Y
F
L
--
L
H
N
---
R
K
--
I
L
N
R
--
A
D
D
S
V
I
R
F
V
D
G
K
R
A
V
I
R
R
S
R
G
F
V
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
62.62
16%
-88
- C5 -
-
3VTH
2
?
A:
[201-389]
-------------------------------------------------------------------------------------------------
F
-
D
-
D
E
I
K
C
V
A
K
A
L
K
E
G
K
I
V
A
I
K
G
I
G
G
F
H
L
A
V
N
A
L
D
D
E
A
V
A
-
T
L
R
R
R
K
K
R
-
Y
G
K
P
F
A
V
M
-
M
R
D
V
E
E
V
K
K
Y
---
C
--
I
---
V
S
P
E
E
E
R
L
L
L
-
S
--
Q
R
R
P
I
V
L
L
K
K
K
G
E
--
K
L
A
K
G
I
A
-
D
D
L
D
T
L
G
V
-
M
L
P
Y
A
P
I
H
Y
L
L
M
E
E
I
D
F
P
-
I
V
M
T
S
-
G
N
V
S
E
E
P
I
C
-
K
D
N
E
E
A
L
E
K
L
K
D
I
A
D
V
F
L
--
L
N
N
---
R
D
IV
N
--
R
--
I
D
D
S
V
T
S
F
N
A
G
A
E
R
I
I
R
R
A
R
G
Y
A
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
59.28
21%
-69
- C5 -
-
1HRU
-
TSAC_ECOLI
A:
[4-144]
-----------------------------------------------------------------------------------------------
N
L
Q
-
R
-
D
A
I
A
A
A
I
D
V
L
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
-
A
A
N
Y
E
Q
L
K
P
Y
IDD
T
--
M
---
L
T
D
V
Q
-
R
E
T
I
-
F
S
R
W
P
G
P
V
T
F
V
F
P
A
P
A
--
T
T
P
R
W
L
T
G
-
R
F
D
S
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
-
A
N
L
S
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
58.10
21%
-25
- C5 -
-
1JCU
-
?
A:
[1-208]
--------------------------------------------------------------------------------------
M
L
I
R
K
I
T
R
K
N
P
S
--P
D
V
L
E
E
A
I
S
V
M
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
C
-
V
S
C
V
D
E
I
P
R
F
---
S
--
R
P
S
---
G
D
A
-
M
E
L
M
-
E
R
I
L
P
G
P
Y
T
V
V
L
E
R
N
E
--
L
I
P
D
V
I
T
G
G
S
S
-
R
V
G
I
-
R
V
P
D
D
E
I
C
R
R
I
A
A
R
--
F
P
-
V
T
A
T
S
-
A
N
I
S
G
K
P
-
P
S
P
R
L
E
E
I
V
R
D
L
D
A
V
D
L
V
L
D
--
A
G
D
---
C
L
--
D
--
M
--
E
P
S
T
V
I
D
L
T
V
N
P
P
R
V
L
R
R
G
K
G
P
L
D
P
V
L
LRGAGDV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
56.01
26%
0
- C- -
-
2EQA
1
SUA5_SULTO
A:
[4-225]
----------------------------------------------------------------------------------------
I
I
K
I
D
P
L
N
P
E
-
I
-
D
K
I
K
I
A
A
D
V
I
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
-
I
A
D
F
N
Q
L
F
E
V
---
A
--
K
D--
I
P
D
K
V
-
L
E
I
A
-
Q
I
V
W
P
G
P
L
T
F
V
L
K
K
T
E
--
R
V
P
K
E
V
T
-
A
G
L
D
T
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
-
A
N
L
A
T
R
P
S
P
-
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
--
D
G
G
---
H
T
--
F
F-
G
--
V
E
S
T
I
I
N
V
T
V
E
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
55.65
22%
-22
- C5 -
-
2MX1
-
TSAC_ECOLI
A:
[3-190]
----------------------------------------------------------------------------------------------
N
N
L
Q
-
R
-
D
A
I
A
A
A
I
D
V
L
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
-
A
A
N
Y
E
Q
L
K
P
Y
---
I
--
D
DTM
L
T
D
V
Q
-
R
E
T
I
-
F
S
R
W
P
G
P
V
T
F
V
F
P
A
P
A
--
T
T
P
R
W
L
T
-
G
R
F
D
S
L
A
V
-
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
-
L
V
S
T
S
-
A
N
L
S
G
L
P
P
C
-
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
V
V
P
--
G
E
T
---
G
G
--
R
--
L
--
N
P
S
E
I
R
D
A
L
T
--
G
E
L
F
R
Q
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.52
27%
0
- C- -
-
3AJE
2
SUA5_SULTO
A:
[5-218]
-----------------------------------------------------------------------------------------
I
K
I
D
P
L
N
P
E
-
I
-
D
K
I
K
I
A
A
D
V
I
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
-
I
A
D
F
N
Q
L
F
E
V
---
A
--
K
D--
I
P
D
K
V
-
L
E
I
A
-
Q
I
V
W
P
G
P
L
T
F
V
L
K
K
T
E
--
R
V
P
K
E
V
T
A
-
G
L
D
T
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
-
A
N
L
A
T
R
P
S
P
-
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
--
D
G
G
HTF
F
G
--
V
--
E
--
S
T
--
I
I
N
V
T
V
E
P
P
V
L
L
R
P
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
53.72
21%
13
- C5 -
-
3TTC
2
?
A:
[12-657]
QIVPDAATC
P
A
C
L
A
E
M
N
TPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAA
F
P
L
C
P
A
C
D
K
E
Y
R
DPLDRRFHAQPVACPEC
G
P
Y
L
E
W
V
S
H
G
E
H
A
E
Q
E
-
A
A
L
Q
A
A
I
A
Q
L
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
A
-
T
L
R
A
R
K
H
R
P
A
K
P
-
L
A
V
M
-
L
P
V
A
D
-----------
G
---
L
P
D
A
A
-
R
Q
L
L
-
T
T
P
A
A
P
I
V
L
V
D
K
K
Y
V
P
--
E
L
C
D
D
I
A
-
P
G
L
N
E
V
G
V
-
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
-
L
V
M
T
S
-
G
N
L
S
G
-
K
P
P
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
IH
N
R
D
---
I
V
--
Q
--
R
--
M
D
D
S
V
V
R
---
E
S
G
E
M
L
R
R
S
R
G
Y
V
P
D
A
L
A
L
P
PGFKNV
P
P
V
L
C
LGADLK
N
T
F
C
L
V
R
GE
Q
V
V
L
S
Q
HLGDLSDDG
I
Q
T
Q
W
R
E
A
L
R
L
M
Q
N
I
Y
NFTPQ
Y
V
V
H
D
AHPGY
V
S
C
Q
W
A
S
E
MN
L
P
T
Q
T
V
L
H
H
H
A
H
A
A
A
C
L
A
E
H
QWPLDG
G
D
V
I
A
L
T
L
D
G
I
G
M
G
E
NG
A
L
W
G
GECLRVNYR
E
C
E
H
L
G
GLPAVALPG
G
D
L
A
A
K
Q
P
W
R
N
L
L
A
Q
C
L
R
FVPEWQNYPET
A
S
V
A
A
ANW
S
V
L
A
R
A
I
E
R
GIN
A
P
L
A
SS
C
G
R
L
F
D
A
V
A
A
A
L
GCAPATLSYEG
E
A
A
C
A
L
E
A
L
A
A
S
CD
G
V
T
H
PVTMPRVDNQLD
L
A
T
F
W
Q
Q
W
L
N
WQAP
V
N
Q
R
A
W
A
F
H
D
A
L
A
Q
G
F
A
A
L
M
R
E
Q
A
T
M
R
GIT
T
L
V
F
S
G
GVIHN
R
L
L
R
A
R
L
A
H
Y
L
AD
F
T
L
L
F
P
Q
SLPAGDGG
L
S
L
G
Q
G
V
I
A
A
A
R
W
L
A
GE
5
PsiBlast_PDB
52.14
27%
0
- C- -
-
4E1B
1
SUA5_SULTO
A:
[5-217]
-----------------------------------------------------------------------------------------
I
K
I
D
P
L
N
P
E
-
I
-
D
K
I
K
I
A
A
D
V
I
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
-
I
A
D
F
N
Q
L
F
E
V
---
A
--
K
D--
I
P
D
K
V
-
L
E
I
A
-
Q
I
V
W
P
G
P
L
T
F
V
L
K
K
T
E
--
R
V
P
K
E
V
T
A
-
G
L
D
T
V
A
V
-
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
-
I
A
A
P
S
-
A
N
L
A
T
R
P
S
P
-
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
--
D
G
G
HTF
F
G
--
V
--
E
--
S
T
--
I
I
N
V
T
V
E
P
-
V
L
L
R
P
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------