@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VU02: (2017-12-16 )
MAITSVIEQMRQLIQLIAKHNHAYYVMDQPTISDSEYDHLFHQLKALEEQYPEFVQADSPTTKVGGQALSKFESVTHVVPMLSLGNVFNQEDLFAFARRVEERLPNQKVQYEVELKLDGLAISLWYENGVLVRGVTRGDGETGEDITQNVKTIRNLPKVLHSEKYEIPRLLEVRGEVLMPKSGFEKLNADQEAKGEKTFANPRNAAAGSLRQLDPNIAAARPLAFYAYGIAQCEPNHGLTTMHDSLQWLTELGFQIAERQYLCNSIQEVQQRYEQIQQERPNLQVEIDGMVVKVDDLKQQQQLGFLSREPRWATAYKFPAQAALTTVEQIDWQVGRTGTLTPVARLNPVFVGGVTVSNVTLHNIGEIHRLDVRIGDTVSVYRTGDVIPKVEKVWPEFRPAEAEVVHLPESCPVCASPVVMPEGEALARCSGGLYCAAQRIEAIRHFVSRKAMDIEGLGDRWVESLLRLDLLKDVADIYHLHEHRETLLGIEKMGEKSVQNLIDAIEASKKTTLARFIYALGIRGVGETTARMLANTFQTLEALKAANVEALKKTPDVGDITAEWIADFFLAPHNIEVLDRLIAAGIHWDAPTAPTRQPLNGESWVLTGTLEQMTRDQATQMLQALGARVSGSVSSKTKCVVAGEKAGSKLEKAAKLGIPVMNETDFLSLMAGYGQTLS
Atome Classification :
(43 SA)
.........10........20........30........40........50........60.......-.-70.........80........90........100..---.-.-..-.110.......120.......130.......140.......150.......160...-.....170.......180.......190.......200.......210.......220.--......230..--.....240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
I
T
S
V
I
E
Q
M
R
Q
L
I
Q
L
I
A
KHN
H
A
Y
Y
V
MDQPTISD
S
E
Y
D
H
L
F
H
Q
L
K
A
L
E
E
Q
Y
P
E
F
VQADSPTTKV
G
G
Q
A
-
L
-
S
-
K
F
E
S
V
T
H
V
V
P
M
L
S
L
G
NVF
N
Q
E
D
L
F
A
F
A
R
R
V
E
E
RL---P-N-Q
K
-
V
Q
Y
E
V
E
L
K
LD
G
L
A
I
S
L
W
YEN
G
V
L
V
R
G
VTRGDGE
T
G
E
D
I
T
Q
N
V
K
T
I
R
N
L
P
K
V
L
H-SEK-YEI
P
R
L
L
E
VRGEVLMPKSGFEKLNADQEAKGEKTFANPRNAAAG
S
L
R
QLDPNIAAARP
L
--
A
F
Y
A
Y
GIAQCE--PNHG
L
T
T
M
H
D
S
L
Q
W
L
T
E
L
G
F
Q
I
A
E
R
Q
Y
L
C
N
S
I
Q
E
V
Q
Q
R
Y
E
Q
I
Q
Q
ERPN
L
Q
V
E
ID
G
M
V
V
K
V
D
D
L
K
Q
Q
Q
Q
LGFLSREPR
W
A
T
A
YKFP
A
Q
A
A
L
T
T
V
E
Q
I
D
WQVGRTGTLTPVARLN
P
V
F
VG
G
V
T
V
S
N
V
T
LHNIG
E
I
H
R
L
D
V
R
IG
D
T
V
S
V
Y
RTGDVIP
K
V
E
K
VWPEFRPAE
A
E
V
V
HLPESCPVCAS
P
V
VMPE
G
E
A
L
A
R
CSG
G
L
Y
C
A
A
Q
R
I
E
A
I
R
H
F
V
S
R
KAMDIEGL
G
D
R
W
V
E
S
L
L
R
L
D
L
L
K
D
V
A
D
I
Y
H
L
H
E
H
R
E
T
L
L
G
I
E
K
M
G
E
K
S
V
Q
N
L
I
D
A
I
E
AS
K
K
T
T
L
A
R
F
I
Y
A
L
GIRGV
G
E
T
T
A
R
M
L
A
N
T
F
Q
T
L
E
A
L
K
A
A
N
V
E
A
L
KKTPDV
G
D
I
T
A
E
W
I
A
D
F
FLAPH
N
I
E
V
L
D
R
L
I
A
AGIHWDAPTAPTRQPLNGE
S
W
V
L
T
G
T
L
E
Q
M
T
R
D
Q
A
T
Q
M
L
Q
A
L
G
A
RVSGSVSSK
T
K
C
V
V
AGEKA
G
S
K
L
E
K
A
A
KLGIPVMN
E
T
D
F
L
S
L
M
A
GYGQTLS
46
HHSearch
84.37
52%
-111
- C8 -
-
4GLX
3
DNLJ_ECOLI
A:
[3-583]
----
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
----
P
-
L
-
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
------------
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
-
G
E
--
N
I
-
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
--
T
F
F
C
Y
G
V
G
V
L
E
--
G
G
E
L
P
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
--
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
------------------------------------------------------------------------------------------
3
PsiBlast_PDB
84.37
51%
-110
- C8 -
-
4GLX
3
DNLJ_ECOLI
A:
[3-586]
----
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
----
P
-
L
-
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
------------
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
-
G
E
N
---
I
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
--
T
F
F
C
Y
G
V
G
V
L
E
--
G
G
E
L
P
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
--
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------
44
HHSearch
83.21
52%
-98
- C8 -
-
5TT5
1
DNLJ_ECOLI
A:
[21-606]
--
M
E
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
-
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
L
----------
V
T
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
-
G
E
--
N
I
-
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
--
T
F
F
C
Y
G
V
G
V
L
E
--
G
G
E
L
P
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
--
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------
2
PsiBlast_PDB
82.76
51%
-98
- C8 -
-
5TT5
1
DNLJ_ECOLI
A:
[21-606]
--
M
E
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
-
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
L
----------
V
T
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
-
G
E
N
---
I
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
--
T
F
F
C
Y
G
V
G
V
L
E
--
G
G
E
L
P
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
--
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.57
51%
1
- C8 -
-
2OWO
3
DNLJ_ECOLI
A:
[1-586]
--
M
E
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
-
A
-
A
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
L
---
K
-
N
N
E
K
-
V
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
H
-
G
E
N
---
I
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
--
T
F
F
C
Y
G
V
G
V
L
E
--
G
G
E
L
P
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
--
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------
21
PsiBlast_CBE
70.02
45%
12
- C8 -
-
1DGS
1
DNLJ_THEFI
B:
[9-581]
--------
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
-
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
A
---
E
-
A
-
P
S
-
L
-
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
-
G
-----
V
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
RA
T
F
Y
A
L
G
L
G
L
G
L
--
E
E
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
-
E
G
K
-
V
H
R
C
P
N
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
--
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------
66
Fugue
69.91
45%
15
- C8 -
-
1DGS
1
DNLJ_THEFI
A:
[1-581]
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
-
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
A
-----
E
-
A
P
-
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
--
T
G
S
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
------
G
V
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
--
R
A
T
F
Y
A
L
G
L
G
L
GL
E
E
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
--
V
K
E
G
K
V
H
R
C
P
N
P
-
L
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
--
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.84
47%
13
- C8 -
-
1V9P
1
DNLJ_THEFI
A:
[9-583]
--------
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
-
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
A
L
---
G
-
R
-
K
R
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
-
G
-----
V
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L
G
L
E
E
----
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
-
E
G
K
-
V
H
R
C
P
N
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
--
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
----------------------------------------------------------------------------------------
22
PsiBlast_CBE
69.45
47%
16
- C8 -
-
1V9P
1
DNLJ_THEFI
B:
[9-583]
--------
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
-
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
A
L
---
G
-
R
-
K
R
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
-
G
-----
V
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
RA
T
F
Y
A
L
G
L
G
L
E
E
----
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
-
E
G
K
-
V
H
R
C
P
N
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
--
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
----------------------------------------------------------------------------------------
4
PsiBlast_PDB
69.28
45%
14
- C8 -
-
1DGS
1
DNLJ_THEFI
A:
[9-581]
--------
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
-
E
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
E
A
---
E
-
A
-
P
S
-
L
-
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
-
G
-----
V
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L
G
L
G
L
--
E
E
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
K
-
E
G
K
-
V
H
R
C
P
N
P
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
--
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------
45
HHSearch
68.33
46%
22
- C8 -
-
1V9P
1
DNLJ_THEFI
B:
[1-581]
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
L
E
-
P
-
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
A
L
---
G
R
K
-
R
P
-
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
K
-
G
----
V
-
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
--
R
A
T
F
Y
A
L
G
L
G
L
--
E
E
S
G
L
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
E
--
G
K
V
H
R
C
P
N
P
-
L
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
--
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
------------------------------------------------------------------------------------------
52
HHSearch
56.60
46%
-78
- C8 -
-
4LH6
2
DNLJ_ENTFA
A:
[6-323]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
-
A
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
56.45
45%
-77
- C8 -
-
4LH6
2
DNLJ_ENTFA
A:
[6-323]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
56.28
45%
-75
- C8 -
-
4EEQ
2
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
56.28
45%
-80
- C8 -
-
3BA8
2
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
56.09
45%
-76
- C8 -
-
4EFB
2
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
55.86
45%
-75
- C8 -
-
1TA8
2
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
55.80
45%
-77
- C8 -
-
4EFE
2
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
55.77
45%
-77
- C8 -
-
3BA9
5
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
HHSearch
55.62
48%
-71
- C8 -
-
1B04
-
DNLJ_GEOSE
B:
[1-313]
M
D
R
Q
Q
A
E
R
R
A
A
E
L
R
E
L
L
N
R
Y
G
Y
E
Y
Y
V
L
D
R
P
S
V
P
D
A
E
Y
D
R
L
M
Q
E
L
I
A
I
E
E
Q
Y
P
E
L
K
T
S
D
S
P
T
Q
R
I
G
G
P
P
-
L
-
E
-
A
F
R
K
V
A
H
R
V
P
M
M
S
L
A
N
A
F
G
E
G
D
L
R
D
F
D
R
R
V
R
Q
E
------
V
-
G
E
-
A
A
Y
V
C
E
L
A
I
D
G
L
A
V
S
V
R
Y
E
D
G
Y
F
V
Q
G
A
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
R
S
L
P
L
R
L
K
-
E
------
P
V
S
L
E
A
R
G
E
A
F
M
P
K
A
S
F
L
R
L
N
E
E
R
K
A
R
--
E
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
K
V
A
A
S
R
Q
L
--
D
L
F
V
Y
G
L
A
D
A
E
--
A
L
G
-
I
A
S
H
S
E
A
L
D
Y
L
Q
A
L
G
F
K
V
N
P
E
R
R
R
C
A
N
I
D
E
V
I
A
F
V
S
E
W
H
D
K
R
P
Q
L
P
Y
E
I
D
G
I
V
I
K
V
D
S
F
A
Q
Q
R
A
L
G
A
T
A
K
S
P
R
W
A
I
A
Y
K
F
P
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
55.54
45%
-74
- C8 -
-
4LH7
2
DNLJ_ENTFA
A:
[6-322]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
55.53
45%
-74
- C8 -
-
3BAA
4
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
55.46
45%
-73
- C8 -
-
3BAB
3
DNLJ_ENTFA
A:
[6-317]
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
-
S
-
G
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
A
I
-----
G
-
K
P
-
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
T
-
E
------
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
--
N
T
F
L
Y
T
V
A
D
F
G
--
P
M
K
A
-
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
52.57
50%
-2
- C8 -
-
4UCU
2
DNLJ_HAEIN
A:
[1-318]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
52.52
50%
-7
- C8 -
-
3PN1
2
DNLJ_HAEIN
A:
[1-318]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
52.48
51%
9
- C8 -
-
3UQ8
2
DNLJ_HAEIN
A:
[2-321]
-----
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
R
L
IL-
L
-
P
-
A
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
--
N
P
-
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
52.44
45%
-59
- C8 -
-
4CC6
1
DNLJ_STAAU
A:
[7-309]
--------
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
-
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
Q
I
---
G
-
N
----
V
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
------
K
-
M
K
E
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
--
S
V
F
I
Y
S
V
N
D
F
---
T
D
F
N
A
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.41
50%
-4
- C8 -
-
4UCS
2
DNLJ_HAEIN
A:
[1-317]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
HHSearch
52.02
45%
-71
* C8 *
-
4GLW
2
DNLJ_STRZP
B:
[2-304]
------
N
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
V
-
L
-
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
E
------
V
-
A
H
-
P
T
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
P
-
E
------
E
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
--
A
T
F
L
Y
Q
E
A
S
P
S
--
T
R
---
D
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
51.94
50%
1
- C8 -
-
3UQ8
2
DNLJ_HAEIN
A:
[5-321]
--------
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
R
L
ILL
P
---
A
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
51.76
50%
-2
- C8 -
-
4UFZ
2
DNLJ_HAEIN
A:
[1-317]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
51.61
45%
-60
- C8 -
-
4CC5
1
DNLJ_STAAU
A:
[7-309]
--------
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
-
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
Q
I
---
G
-
N
----
V
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
------
K
-
M
K
E
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
--
S
V
F
I
Y
S
V
N
D
F
---
T
D
F
N
A
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
51.46
51%
8
- C8 -
-
3PN1
2
DNLJ_HAEIN
A:
[3-318]
----
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
IL-
L
-
P
-
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
--
N
P
-
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.29
50%
-2
- C8 -
-
4UCT
2
DNLJ_HAEIN
A:
[1-318]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
51.18
50%
-3
- C8 -
-
4UCR
2
DNLJ_HAEIN
A:
[1-317]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
51.17
45%
-64
- C8 -
-
5FPO
3
DNLJ_STAAU
A:
[7-309]
--------
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
-
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
-
A
-
S
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
Q
I
---
G
-
N
----
V
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
------
K
-
M
K
E
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
-
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
--
S
V
F
I
Y
S
V
N
D
F
---
T
D
F
N
A
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
51.04
44%
-70
- C8 -
-
4GLW
2
DNLJ_STRZP
B:
[3-304]
-------
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
V
-
L
-
D
-
G
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
E
V
---
A
-
H
-
P
T
---
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
P
-
E
E
------
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
--
A
T
F
L
Y
Q
E
A
S
P
S
--
T
R
D
---
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
V
V
N
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.84
50%
-2
- C8 -
-
4UCO
2
DNLJ_HAEIN
A:
[1-317]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
50.38
50%
-2
- C8 -
-
4UCV
2
DNLJ_HAEIN
A:
[1-318]
--
M
T
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
-
S
-
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
D
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
47.11
43%
-1
- C8 -
-
1ZAU
1
DNLJ_MYCTU
A:
[13-328]
-----
V
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
-
F
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
V
-----
G
-
D
A
-
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
P
G
D
D
-
Y
P
V
P
E
V
L
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
--
R
M
I
C
H
G
L
G
H
V
E
---
G
F
R
P
A
T
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
E
H
T
T
L
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.77
40%
13
- C8 -
-
3SGI
1
DNLJ_MYCTU
A:
[13-415]
-----
V
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
-
F
A
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
V
-----
G
-
D
A
-
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
P
G
D
D
-
Y
P
V
P
E
V
L
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
--
R
M
I
C
H
G
L
G
H
V
E
---
G
F
R
P
A
T
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
E
H
T
T
L
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
E
A
Q
T
K
L
L
D
I
R
V
N
V
G
R
T
G
R
I
T
P
F
A
F
M
T
P
V
K
V
A
G
S
T
V
G
Q
A
T
L
H
N
A
S
E
I
K
R
K
G
V
L
I
G
D
T
V
V
I
R
K
A
G
D
V
I
P
E
V
L
G
P
V
V
E
L
R
D
G
S
E
R
E
F
I
M
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
HHSearch
46.68
43%
-1
- C8 -
-
1ZAU
1
DNLJ_MYCTU
A:
[8-328]
Q
T
A
P
E
V
L
R
Q
W
Q
A
L
A
E
E
V
R
E
H
Q
F
R
Y
Y
V
R
D
A
P
I
I
S
D
A
E
F
D
E
L
L
R
R
L
E
A
L
E
E
Q
H
P
E
L
R
T
P
D
S
P
T
Q
L
V
G
G
A
G
F
A
-
T
-
D
F
E
P
V
D
H
L
E
R
M
L
S
L
D
N
A
F
T
A
D
E
L
A
A
W
A
G
R
I
H
A
E
V
-----
G
-
D
A
-
A
H
Y
L
C
E
L
K
I
D
G
V
A
L
S
L
V
Y
R
E
G
R
L
T
R
A
S
T
R
G
D
G
R
T
G
E
D
V
T
L
N
A
R
T
I
A
D
V
P
E
R
L
T
-
P
G
D
D
Y
P
V
P
E
V
L
E
V
R
G
E
V
F
F
R
L
D
D
F
Q
A
L
N
A
S
L
V
E
E
G
K
A
P
F
A
N
P
R
N
S
A
A
G
S
L
R
Q
K
D
P
A
V
T
A
R
R
R
L
--
R
M
I
C
H
G
L
G
H
V
E
--
G
F
R
-
P
A
T
L
H
Q
A
Y
L
A
L
R
A
W
G
L
P
V
S
E
H
T
T
L
A
T
D
L
A
G
V
R
E
R
I
D
Y
W
G
E
H
R
H
E
V
D
H
E
I
D
G
V
V
V
K
V
D
E
V
A
L
Q
R
R
L
G
S
T
S
R
A
P
R
W
A
I
A
Y
K
Y
P
P
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
44.35
50%
-7
- C8 -
-
3BAC
1
DNLJ_HAEIN
A:
[6-260]
-------------------------------------------------------------------------
G
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
L
ILL
P
---
K
P
-
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
L
-
T
D
N
---
P
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
--
V
L
N
A
Y
G
I
G
I
A
E
--
G
V
G
L
P
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
D
F
Y
Q
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------