@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUB5: (2017-12-17 )
MNTIDITNSLEKDKLVNTEQSQLTDTQLHHGTSYVSHFEPHASKKPNSTEIKISAQDAHVYYGDFEAIKGIDLDIYQNEVIAFIGPSGCGKSTFLRTLNRMNDTIDGCRVTGKITLDNKNIYDPNLDVVLLRAQVGMVFQKPNPFPKSIFDNVAYGPKLHGLARDKYDLEEIVENSLRKAGLWEEVKDRLNQPGTGLSGGQQQRLCIARTIAVSPEVILMDEPCSALDPIATAKVEELISELSDQYTIVIVTHSMQQAARVSDRTAYFHLGDLIEVNSTEKVFTQPDHQLTEAYITGRFG
Atome Classification :
(27 SA)
.........10........20........30........40........50........60........70........80........90........100.......---110.......120.-......------130.......140.-....-..150.------...---.--..160.......170.......180.......190.......200.......210.......220.......230...-....240-.--..-.--...250.......260.......270.......280.......290.......300-------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
N
T
I
DITNSLEKDKLVNT
E
Q
SQLTDTQLHHGT
S
Y
V
S
HFEPHASKKPNS
T
E
I
K
I
SAQD
A
H
V
Y
YGD
F
E
A
IKGI
D
L
D
I
YQN
E
V
I
A
F
IGPSGC
G
K
S
T
F
L
R
T
L
N
R
MNDTIDG
C
R
---
V
T
G
K
I
T
LDNKNIYD-PNL
D
V
V
------
L
L
R
A
QV
G
M
V
FQKPN-PF
P
K
-
S
I
F
DNV------AYG---P--KLHGLARDKY
D
L
E
E
I
V
E
N
S
L
R
KAG
L
W
E
E
V
K
D
R
LNQPGTGLSGGQ
Q
Q
R
L
C
I
A
R
T
IAVS
P
E
V
I
L
MDEPCSALD
P
I
A
T
A
K
V
-
E
E
L
I
S
E
L-S--D
Q
-
Y
--
T
I
V
I
V
TH
S
M
Q
Q
A
ARVSD
R
T
A
Y
F
HLG
D
L
I
E
VNSTE
K
V
FTQPD
H
Q
L
T
E
A
Y
ITGRFG---------------------------------------------------------------------------------------------
72
Fugue
79.17
30%
-36
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
-
H
M
I
K
L
S
N
--------------------------
I
T
K
V
F
H
Q
G
T
-------------------
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
--------
T
E
G
S
V
L
V
D
G
Q
E
L
T
T
L
S
E
S
E
L
T
------
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
-
T
V
F
G
N
V
------
A
L
P
---
L
--
E
L
D
N
--
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
----
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
-
L
E
L
L
K
D
I
-
N
--
R
R
-
L
GL
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
LDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
22
PsiBlast_CBE
76.17
39%
-9
- C1 -
-
3C4J
2
?
B:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
28
PsiBlast_CBE
74.48
39%
-14
- C1 -
-
2OLK
1
?
C:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
4
PsiBlast_PDB
74.31
39%
-12
- C1 -
-
2OUK
-
?
A:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.23
39%
-10
- C1 -
-
2OLJ
3
?
A:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
21
PsiBlast_CBE
73.75
39%
-15
- C1 -
-
3C41
2
?
K:
[13-242]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
73.75
39%
-7
- C1 -
-
2Q0H
3
?
A:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
13
PsiBlast_PDB
73.47
35%
-38
- C1 -
-
4YMW
-
?
J:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
73.33
39%
-13
- C1 -
-
2OLK
2
?
B:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
1
PsiBlast_PDB
73.18
39%
-9
- C1 -
-
3C41
2
?
J:
[13-242]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
34
PsiBlast_CBE
72.89
35%
-39
- C1 -
-
4YMV
1
?
A:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
72.33
39%
-10
- C1 -
-
2OLK
1
?
D:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
35
PsiBlast_CBE
71.60
35%
-35
- C1 -
-
4YMU
1
?
A:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
71.59
35%
-31
- C1 -
-
4YMU
1
?
J:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
71.28
39%
-16
- C1 -
-
2OLK
1
?
A:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
6
PsiBlast_PDB
70.97
39%
-7
- C1 -
-
3C4J
2
?
A:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M
-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
10
PsiBlast_PDB
70.74
35%
-34
- C1 -
-
4YMT
-
?
J:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
70.66
35%
-33
- C1 -
-
4YMV
1
?
J:
[2-237]
----------------------------------------------------
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
--------
T
K
G
E
V
F
I
D
G
V
K
I
N
N
-
G
K
V
N
I
N
------
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
-
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
---
P
V-
K
V
K
K
M
--
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
----
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
-
L
N
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
-------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
70.15
39%
-15
- C1 -
-
2Q0H
3
?
B:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
14
PsiBlast_PDB
69.66
34%
-25
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-255]
--------------------------------------------------
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
---
I
V
N
G
Q
N
I
N
L
V
R
D
K
D
-
G
Q
L
K
V
A
D
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
-
L
W
S
H
M
T
V
L
E
N
V
------
M
E
A
---
P
---
I
Q
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
P
---
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
-
L
R
I
M
Q
Q
L
-
A
--
E
E
G
K
--
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
K
G
------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
69.65
39%
-13
- C1 -
-
2OLJ
2
?
B:
[34-263]
-------------------------------------------------------------
F
G
S
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
---
I
I
D
G
I
N
L
K
A
K
---
D
-
T
N
L
N
K
V
--------
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
---
P
M-
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
--
E
L
L
D
K
V
G
L
----
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
-
L
S
V
M
K
Q
L
-
A
--
N
E
G
M
--
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
----------------------------------------------------------------------------------------------
65
PsiBlast_CBE
54.36
32%
-47
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[23-235]
----------------------------------------------------------------------
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
--------
D
S
G
E
I
S
L
S
G
K
T
I
F
S
-
K
N
T
N
L
P
------
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
-
L
F
P
H
L
T
V
Y
R
N
I
------
A
Y
G
---
L
--
G
-
N
G
K
G
R
T
A
Q
E
R
Q
R
I
-
E
A
M
L
E
L
T
G
I
S
E
L
A
G
R
Y
P
H
E
----
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
--
N
G
-
K
--
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
-----------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
54.26
32%
-44
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[23-230]
----------------------------------------------------------------------
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
--------
D
S
G
E
I
S
L
S
G
K
T
I
F
S
-
K
N
T
N
L
P
------
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
-
L
F
P
H
L
T
V
Y
R
N
I
------
A
Y
G
---
L
--
G
-
N
G
K
G
R
T
A
Q
E
R
Q
R
I
-
E
A
M
L
E
L
T
G
I
S
E
L
A
G
R
Y
P
H
E
----
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
--
N
G
-
K
--
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
-----------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
48.72
34%
20
- C1 -
-
1L2T
3
Y796_METJA
B:
[20-229]
------------------------------------------------------------------
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
--------
N
I
I
G
C
L
DKP
T
E
G
E
V
Y
I
D
N
I
K
T
N
D
-
L
D
D
D
E
L
TK----
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
-
L
I
P
L
L
T
A
L
E
N
V
ELPLIF
K
Y
R
---
G
--
A
M
S
G
E
E
R
R
K
R
A
L
E
-----
C
L
K
M
A
E
L
E
E
R
F
A
---
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
-
M
Q
L
L
K
K
L
-
N
EE
D
G
-
K
--
T
V
V
V
V
T
H
D
I
-
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
---
E
V
E
R
E
E
K
L
---------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
47.68
31%
-52
- C1 -
-
4AYT
1
ABCBA_HUMAN
A:
[363-567]
----------------------------------------------------------------------
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
Y
D
P
--------
A
S
G
T
I
S
L
D
G
H
D
I
R
Q
---
L
N
P
V
------
W
L
R
S
K
I
G
T
V
S
Q
E
P
I
-
L
F
S
C
-
S
I
A
E
N
I
------
A
Y
G
ADD
P
--
S
-
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
-
Q
E
A
L
D
R
L
-
M
--
D
G
-
R
--
T
V
L
V
I
A
H
R
L
-
S
T
I
K
N
A
N
M
V
A
V
L
D
Q
G
K
I
T
E
Y
G
K
H
E
E
----------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
44.52
31%
-46
- C1 -
-
4AYX
1
ABCBA_HUMAN
A:
[363-573]
----------------------------------------------------------------------
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
Y
D
P
--------
A
S
G
T
I
S
L
D
G
H
D
I
R
Q
---
L
N
P
V
------
W
L
R
S
K
I
G
T
V
S
Q
E
P
I
-
L
F
S
C
-
S
I
A
E
N
I
------
A
Y
G
ADD
P
--
S
-
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
-
Q
E
A
L
D
R
L
-
M
--
D
G
-
R
--
T
V
L
V
I
A
H
R
L
-
S
T
I
K
N
A
N
M
V
A
V
L
D
Q
G
K
I
T
E
Y
G
K
H
E
E
L
L
S
K
P
N
----------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
42.66
31%
-39
- C1 -
-
4AYW
1
ABCBA_HUMAN
A:
[394-598]
----------------------------------------------------------------------
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
Y
D
P
--------
A
S
G
T
I
S
L
D
G
H
D
I
R
Q
---
L
N
P
V
------
W
L
R
S
K
I
G
T
V
S
Q
E
P
I
-
L
F
S
C
-
S
I
A
E
N
I
------
A
Y
G
---
A
DD
P
S
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
F
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
N
P
K
I
L
L
L
D
E
----
L
D
A
E
N
E
Y
L
V
-
Q
E
A
L
D
R
L
-
M
--
D
G
-
R
--
T
V
L
V
I
A
H
H
L
-
S
T
I
K
N
A
N
M
V
A
V
L
D
Q
G
K
I
T
E
Y
G
K
H
E
E
----------------------------------------------------------------------------------------------------------------