@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUL5: (2017-12-19 )
MKQLKLEVIFGSQDKLSPALKILSGNSNAAARALKQTKDQVKNLESQLAKIDSYEKQKLIVQQSSIALKNMQNQVKHLKAEIAQNPANNLAKSLEQTQQQIKATEAAKKQLDQQLKRIDAFRQQKQAALDTTKSYQAVQARIADLKRQMDAQPSKKLTQEFNRASREAEQLKNRINEQAIALQRSRNDLNQYGISTRNLSNEHIRVRREIEHSNRTIDQQKQSLRQLKEEHKQSQSSLCGLTQQLTNSEREVGKLTAEYDKQKLHLKNLSRELDLSGVSVNQLATHQGKLKDRLSSTNSQLDKQQRQMSQLTRMQQNYQKVQQHSRTAMIYGVGTTAAGTAAMYQLRKPIEENKRVEIEENRIASLGLGEKATKEATAYAKAMKTFGTSTFDNLQLMRDGITAFADVHHTEMVAPTLSKMKFANEAMYGHEQGSENERKFMDMLKVIELRNGLRSEKAFQEQANIIQQVITATGGRVQAGEWLNAIKTGGVAVKGLSNEAFYYKMEPIVQELGGHRFGTSAMSAYQNIYQGRTTKRAANNLLELGLIADQSKVTHDKAGQVSFLNPGALKGAELFKRDQFAWMEQVLLPTLAEKGITSRDQIHDTIGSIFTNRNASNLFTTMYDQREQIHKNAKLNAGADNIDQLNSKAMNTTSGKELEARAKLNDAYLNFGQNILPIYTSAIEVATEALKGFNTWMQQNPTLAKLLGAGLLVIATSLVAIGGALVVFSPLILSMLSLRLLMTTVGAKGSSLGFVFRMLSGPVGILQKGFGFLGRSILWLSRLFIANPILLAVTAIAGAAYLIYQNWGAITGFFSGVWSSVKQIFSDGWNAIKSVIQSVDSIFANNPILTFIFPFIGIPRLIIANWSSISSFFSGLWNGIVSGANNLWTNITQIFSPIGTWFLNQWISVKTNTAQAWTAIKTAVSNAWSSLVSSIQTNPILQKIMSGWQSILTYLQSLKDQMLGIGRNIIDGLISGIKSGFNGLKSLWAQINNYMPDFMRKKMDIHSPSRVMRGIGRFIVAGLEVGLGQQHGSLQKTYKRIVDTFTAPTPVTFTPGANPPDQQQTLWQRVVYAKLPEIMNQNQNIQQVLQPAEIPTIADQTQGIWQKLFKVKVPKILGMNQTISQVLQPATMPEIPDQQQNILQSLHPAIILDLPDQKQSILQKVVALAKPIIEGAPIFKLFGQIKNEWNRLWAGLDNIADKFPERLKMLLDVQPAEQPTLAMPSFTPPQLPPVMVKPLRAGVSASAGEQASKPHQIKVEGDSIAIYVTAQPGQSTNDIAAQIRRELESYQREKEMRIRDQFWDNQ
Atome Classification :
(20 SA)
-.........10........20........30........40........50.....-...60........70........80...--.....90........100.......110...-....120..----.....130.......140.........150...-----.....-.160.......170...--....180--.........190....-----.-----...200.......210-........220.......230.......240.......250...--------....260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450----.........460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920----........930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-M
K
Q
L
K
L
E
V
I
FGSQDKL
S
P
A
L
KILSGN
S
N
A
A
A
R
A
L
K
Q
T
K
D
Q
V
K
N
L
E
S
Q
L
A
KID
S
Y
E
K
-
Q
K
L
I
V
QQ
S
S
I
A
L
K
N
M
Q
N
Q
V
K
H
L
K
A
E
I
AQ--N
P
A
N
N
L
A
K
S
L
E
Q
T
Q
Q
Q
I
K
A
T
E
A
A
K
K
Q
L
D
Q
Q
L
-
K
R
I
D
A
F
R
Q
Q
----
K
Q
A
ALDT
T
K
S
Y
Q
A
V
Q
A
--
R
I
A
D
L
K
R
Q
MD--AQ
P
-----
S
K
K
L
T
-
Q
E
F
N
R
A
S
R
E
A
E
Q
L
K
N
R
I
--
N
E
Q
A
I
----
A
L
Q
R
SRN
D
L
N
-
Q
YGIS-----T-----RNLSN
E
H
I
R
V
R
R
E
I
E--HSNR
T
I
D
Q
Q
K
Q
S
L
R
Q
L
K
E
E
H
K
Q
S
Q
S
S
L
C
G
L
T
Q
Q
L
T
N
S
E
R
E
V
G
K
L
--------
T
A
E
Y
D
K
Q
K
L
H
L
K
N
L
S
R
ELDLSGV
S
V
N
Q
L
A
T
H
Q
G
K
L
K
D
R
L
SS
T
N
S
Q
L
D
K
Q
Q
R
Q
M
S
Q
L
T
R
M
Q
Q
N
Y
Q
K
V
Q
Q
HSR
T
A
M
I
Y
GVGTTA
A
G
T
A
A
M
Y
Q
L
RKPIEEN
K
R
V
E
I
EEN
R
I
A
SLGLGE
K
A
T
K
E
A
T
A
Y
A
K
A
M
K
T
FGTST
F
D
N
L
Q
L
M
R
D
G
I
T
A
F
A
DVH
H
T
E
MV
A
P
T
L
S
K
M
K
FANEAMYGHEQGS
E
N
E
R
K
F
M
D
M
L
K
V
I
E
L
R
------NGLR
S
E
K
A
F
Q
E
Q
A
N
I
I
Q
Q
V
I
T
ATGGRV
Q
A
G
E
W
L
N
A
I
KTG
G
V
A
V
KGLSNE
A
F
Y
Y
K
M
E
P
I
V
Q
E
LGGHRF
G
T
S
A
M
S
A
Y
Q
N
I
YQGRT
T
K
R
A
A
N
N
L
L
E
LGLIADQSKVTHDKAG
Q
V
S
FLNPGAL
K
G
A
E
L
F
K
R
D
Q
F
A
W
M
E
Q
V
L
L
P
T
L
A
EKGIT
S
R
D
Q
I
H
D
T
I
G
S
I
FTNR
N
A
S
N
L
F
T
T
M
Y
D
Q
R
E
Q
I
H
KNAKLNAGAD
N
I
D
Q
L
N
S
KAMNTTSGK
E
L
E
A
R
AKL
N
D
A
Y
L
N
FGQ
N
I
L
P
I
Y
T
S
A
I
E
V
A
T
E
A
L
K
G
F
N
T
W
M
QQNP
T
L
A
K
L
L
GA
G
L
L
V
I
A
T
S
L
V
A
IG
G
A
L
V
V
F
S
P
L
I
L
S
M
L
S
L
R
L
L
M
T
TVGAKG
S
S
L
G
F
V
F
R
M
LSG
P
V
G
I
L
Q
K
G
F
G
F
L
G
R
S
I
L
W
L
S
R
L
F
IAN
P
I
L
L
A
V
T
A
IA
G
A
A
Y
L
I
Y
QNW
G
A
I
T
G
F
F
S
G
V
W
S
S
V
K
Q
I
F
SD
G
W
N
A
I
K
S
V
I
Q
S
V
D
S
I
FANN
P
I
L
T
F
I
F
P
F
IGI
P
R
L
I
IA
N
W
S
S
I
S
S
F
F
S
G
L
W
N
G
I
V
SG
A
N
N
L
W
T
N
I
T
Q
I
F
S
P
I
G
T
W
F
L
N
Q
W
I
S
V
KTNT
A
Q
A
W
T
A
I
K
-----
T
A
V
S
N
A
W
S
S
L
V
S
S
IQT
N
P
I
L
Q
K
I
M
S
G
W
Q
S
I
L
T
Y
L
Q
S
L
K
D
Q
M
L
G
I
G
R
N
I
I
D
G
L
I
S
G
I
K
S
G
F
N
G
L
K
S
L
W
A
Q
I
N
N
Y
M
P
D
F
M
R
K
KMDIH
S
P
S
R
V
M
R
G
I
G
R
F
I
V
A
G
L
EVGLGQQH
G
S
L
Q
K
T
Y
K
R
I
V
D
T
FTAPT
P
V
T
FTPGANPP
D
Q
Q
Q
T
L
W
Q
R
V
V
Y
A
K
L
P
E
I
MNQNQ
N
I
Q
Q
V
LQPAEIP
T
I
A
D
Q
T
Q
G
I
W
Q
K
L
F
K
VK
V
P
K
ILG
M
N
Q
T
I
S
Q
VLQPATMPEIP
D
Q
Q
Q
N
I
L
Q
SLH
P
A
I
I
L
DLPD
Q
K
Q
S
I
L
Q
K
V
V
A
L
A
K
P
I
IEGA
P
I
F
K
L
F
G
Q
I
K
N
E
W
N
R
L
W
A
G
L
D
N
I
A
D
K
F
P
E
R
L
K
M
L
LDVQPAEQPTLAMPSFTPPQLP
P
V
M
V
K
P
L
R
AGVSASAGEQASKP
H
Q
I
K
V
EG
D
S
I
A
I
Y
V
TAQPGQST
N
D
I
A
A
Q
I
R
R
E
L
E
S
Y
Q
R
E
K
E
M
R
I
R
D
Q
FWDNQ
3
PsiBlast_PDB
78.19
20%
0
- C- -
-
2W49
-
TNNC2_CHICK (first)
A:
[23-268]
-----------------------------------
K
A
A
E
D
R
S
K
Q
L
E
D
E
L
V
S
L
Q
K
K
L
K
G
T
E
D
E
L
D
K
Y
S
E
A
L
K
D
A
Q
E
-----
K
L
E
L
A
E
--
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
V
E
---
E
E
L
D
R
A
Q
-
E
R
L
A
T
A
L
Q
K
L
E
E
A
E
K
A
A
D
E
S
E
R
G
M
K
V
I
E
S
--
R
A
Q
K
D
E
E
K
M
E
--
I
Q
E
I
Q
L
K
E
A
K
H
I
A
-
E
D
A
D
R
K
Y
E
E
V
A
R
-
K
L
V
I
--
I
E
S
D
L
----
E
R
A
E
E
R
A
E
L
S
-
E
G
K
C
A
-----
E
L
E
E
E
L
K
T
V
T
N
N
L
K
S
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
T
R
A
E
F
A
E
R
S
V
T
K
L
E
K
S
I
D
D
L
--------
E
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
72.28
19%
125
- C3 -
-
5XG2
2
?
A:
[51-246]
---------------------------------------------------
V
K
E
L
E
E
-
A
R
K
S
L
Y
E
G
E
A
R
I
K
R
A
E
E
E
K
E
R
L
K
A
E
I
L
T
--
G
E
A
R
-
L
P
G
L
R
E
R
A
E
N
L
R
R
L
V
E
E
K
R
A
E
I
S
E
L
E
-
R
R
L
S
S
I
T
S
-------------
Q
S
F
E
-
L
R
I
--
K
L
S
D
L
E
K
E
L
E
L
A
R
K
D
-----
L
E
K
V
L
-
A
E
E
R
A
V
R
E
E
I
E
V
A
K
R
R
I
--
N
E
L
D
T
----
L
I
E
R
E
R
G
E
L
-------------------------
A
K
L
R
G
R
I
E
--
R
L
E
R
K
R
D
K
L
K
K
A
L
-----
E
N
P
E
A
R
E
----
L
T
E
K
I
R
A
V
E
K
E
I
A
A
L
--------
R
E
E
L
S
R
V
E
G
K
L
E
G
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
69.73
20%
-
- C3 -
-
2TMA
-
TPM1_RABIT
A:
[30-275]
-----------------------------------
K
A
A
E
D
R
S
K
Q
L
E
D
E
L
V
S
L
Q
K
K
L
K
G
T
E
D
E
L
D
K
Y
S
E
A
L
K
D
A
Q
E
-----
K
L
E
L
A
E
--
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
V
E
---
E
E
L
D
R
A
Q
-
E
R
L
A
T
A
L
Q
K
L
E
E
A
E
K
A
A
D
E
S
E
R
G
M
K
V
I
E
S
--
R
A
Q
K
D
E
E
K
M
E
--
I
Q
E
I
Q
L
K
E
A
K
H
I
A
-
E
D
A
D
R
K
Y
E
E
V
A
R
-
K
L
V
I
--
I
E
S
D
L
----
E
R
A
E
E
R
A
E
L
S
-
E
G
K
C
A
E
L
E
E
E
I
-----
K
T
V
T
N
N
L
K
S
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
T
R
A
E
F
A
E
R
S
V
T
K
L
E
K
S
I
D
D
L
--------
E
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
62.72
20%
119
- C3 -
-
1C1G
-
TPM1_PIG
A:
[30-275]
-----------------------------------
K
A
A
E
D
R
S
K
Q
L
E
D
E
L
V
S
L
Q
K
K
L
K
A
T
E
D
E
L
D
K
Y
S
E
A
L
K
D
A
Q
E
-----
K
L
E
L
A
E
--
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
F
E
---
E
E
L
D
R
A
Q
-
E
R
L
A
T
A
L
Q
K
L
E
E
A
E
K
A
A
D
E
S
E
R
G
M
K
V
I
E
S
--
R
A
Q
K
D
E
E
K
M
E
--
I
Q
E
I
Q
L
K
E
A
K
H
I
A
-
E
D
A
D
R
K
Y
E
E
V
A
R
-
K
L
V
I
--
I
E
S
D
L
----
E
R
A
E
E
R
A
E
L
S
-
E
G
K
C
A
E
L
E
E
E
I
-----
K
T
V
T
N
N
L
K
S
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
T
R
A
E
F
A
E
R
S
V
T
K
L
E
K
S
I
D
D
L
--------
E
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
62.24
24%
176
- C3 -
-
3VKG
-
?
A:
[1911-2224]
--------------------------------------------------
K
R
D
Q
L
E
E
-
E
Q
L
H
L
N
I
G
L
K
K
L
R
D
T
E
A
Q
V
K
D
L
Q
V
S
L
A
Q
--
K
N
R
E
L
D
V
K
N
-
E
Q
A
N
Q
K
L
K
--
Q
M
V
Q
D
Q
Q
A
A
E
I
-
K
Q
K
D
A
--
R
E
----
L
Q
V
Q
L
D
V
R
N
K
E
I
A
V
Q
K
V
K
A
Y
A
D
L
-----------------
P
L
R
-
E
E
V
E
Q
L
E
N
A
A
N
E
L
K
L
K
Q
--
D
E
I
V
A
----
T
I
T
A
L
E
K
S
I
A
-
T
Y
K
E
E
-----
Y
-----
A
T
L
I
R
E
T
E
Q
I
K
T
E
S
S
--
K
V
K
N
K
V
D
R
S
I
A
L
L
D
N
L
N
S
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.57
20%
120
- C3 -
-
2W4U
-
TPM1_RABIT
A:
[23-268]
-----------------------------------
K
A
A
E
D
R
S
K
Q
L
E
D
E
L
V
S
L
Q
K
K
L
K
G
T
E
D
E
L
D
K
Y
S
E
A
L
K
D
A
Q
E
-----
K
L
E
L
A
E
--
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
V
E
---
E
E
L
D
R
A
Q
-
E
R
L
A
T
A
L
Q
K
LEEA
E
K
A
A
D
E
S
E
R
G
M
K
V
I
E
S
--
R
A
Q
K
D
E
E
K
M
E
--
I
Q
E
IQLKE
A
K
H
I
A
-
E
D
A
D
R
K
Y
E
E
V
A
R
-
K
L
V
I
--
I
E
S
D
L
----
E
R
A
E
E
R
A
E
L
S
-
E
G
K
C
A
-----
E
LEEEL
K
T
V
T
N
N
L
K
S
L
E
A
Q
A
E
--
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
T
R
A
E
F
A
E
R
S
V
T
K
L
E
K
S
I
D
D
L
--------
E
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
58.64
10%
190
- C3 -
-
2CH7
-
MCP2_THEMA
A:
[1-309]
G
S
H
M
K
D
V
Q
T
E
T
F
S
V
A
E
S
I
E
E
I
S
K
A
N
E
E
I
T
N
Q
L
L
G
I
S
K
E
M
D
N
I
S
T
R
I
E
S
I
S
A
S
V
Q
E
T
T
-
A
G
S
E
E
I
S
S
A
T
K
N
I
A
D
S
A
Q
Q
A
A
S
F
A
D
Q
S
T
--
Q
L
A
K
E
A
G
D
A
L
K
K
V
I
E
V
T
R
M
I
S
N
S
A
K
D
V
E
R
V
V
-
E
S
F
Q
K
G
A
E
E
----
I
T
S
F
V
E
T
I
N
A
-
I
A
E
Q
T
--
N
L
L
A
L
N
A
A
I
E
--
A
A
R
-----
A
G
E
A
G
-
R
G
F
A
V
V
A
D
E
I
R
K
L
A
E
E
S
--
Q
Q
A
S
E
----
N
V
R
R
V
V
N
E
I
R
-
S
I
A
E
D
-----
A
-----
G
K
V
S
S
E
I
T
A
R
V
E
E
G
T
--
K
L
A
D
E
A
D
E
K
L
N
S
I
V
G
A
V
E
R
I
N
E
M
L
Q
N
I
A
A
A
I
E
E
Q
T
A
A
V
D
E
I
T
T
A
--------
M
T
E
N
A
K
N
A
E
E
I
T
N
S
V
K
E
V
N
A
R
L
Q
E
I
S
A
S
T
E
E
V
T
S
R
V
Q
T
I
R
E
N
V
Q
M
L
K
E
I
V
A
R
Y
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
55.79
16%
58
- C3 -
-
5HMO
-
MYO10_BOVIN
A:
[1-131]
-------------------------------------------------------------------
Q
K
Q
L
R
G
Q
I
A
R
R
V
Y
R
Q
L
L
A
E
--
K
R
A
E
E
E
K
R
K
R
E
E
E
E
K
R
K
R
E
E
E
E
R
E
R
E
R
E
R
R
E
-
A
E
L
R
A
Q
Q
E
E
----
A
A
R
K
Q
R
E
L
E
A
L
Q
Q
E
S
Q
--
R
A
A
E
L
S
R
E
L
E
--
K
Q
K
-----
E
N
K
Q
V
-
E
E
I
L
R
L
E
K
E
I
E
D
L
Q
R
M
K
--
E
R
Q
E
L
----
S
L
T
E
A
S
L
Q
K
L
-
Q
Q
L
R
D
-----
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
53.93
13%
31
- C3 -
-
1VLT
2
MCP2_SALTY
A:
[5-146]
-----------------------------------------------
G
F
V
I
S
N
E
L
R
Q
-
Q
Q
S
E
L
T
S
T
W
D
L
M
L
Q
T
R
I
N
L
S
R
S
A
A
R
M
M
M
--
D
A
S
N
Q
Q
S
S
A
K
T
D
L
L
Q
N
A
K
T
T
L
A
Q
A
A
A
H
Y
A
N
F
-
K
N
M
T
P
L
P
A
M
----
A
E
A
S
A
N
V
D
E
K
Y
Q
R
Y
Q
A
--
A
L
A
E
L
I
Q
F
L
D
--
N
G
N
-----
M
D
A
Y
F
A
Q
P
T
Q
G
M
Q
N
A
L
G
E
A
L
G
N
Y
--
A
R
V
S
E
----
N
L
Y
R
Q
T
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
53.27
22%
129
- C3 -
-
3K6B
1
A:
[24-151]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
D
--
E
K
H
-----
R
K
K
V
-----
D
K
V
M
K
E
W
G
D
L
E
T
R
Y
--
N
E
Q
K
A
KD
P
K
G
A
E
K
F
K
S
Q
M
N
A
R
F
Q
K
T
-----
V
-----
S
S
L
E
E
E
H
K
R
M
R
K
E
I
E
A
V
H
E
E
R
V
Q
A
M
L
N
E
K
K
R
D
A
T
H
D
Y
R
Q
A
L
A
T
H
V
N
K
P
N
K
H
S
V
L
Q
S
L
K
A
Y
I
--------
R
A
E
-
E
K
D
R
M
H
T
L
N
R
Y
R
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.72
22%
126
- C3 -
-
3K66
-
A4_CAEEL
A:
[257-384]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
D
--
E
K
H
-----
R
K
K
V
-----
D
K
V
M
K
E
W
G
D
L
E
T
R
Y
--
N
E
Q
K
A
KD
P
K
G
A
E
K
F
K
S
Q
M
N
A
R
F
Q
K
T
-----
V
-----
S
S
L
E
E
E
H
K
R
M
R
K
E
I
E
A
V
H
E
E
R
V
Q
A
M
L
N
E
K
K
R
D
A
T
H
D
Y
R
Q
A
L
A
T
H
V
N
K
P
N
K
H
S
V
L
Q
S
L
K
A
Y
I
--------
R
A
E
-
E
K
D
R
M
H
T
L
N
R
Y
R
H
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
51.41
14%
-
- C3 -
-
4RFX
-
DCTN1_CHICK
A:
[432-531]
----------------------------------------
M
V
E
T
L
T
E
R
N
L
D
L
E
E
K
V
R
-
E
L
R
E
T
V
G
D
L
E
A
M
N
E
M
N
D
E
L
Q
E
N
A
R
E
T
E
L
--
E
L
R
E
Q
L
D
L
A
A
A
R
V
R
E
A
E
K
R
V
E
A
A
Q
E
T
V
A
D
Y
Q
-
Q
T
I
K
K
Y
R
E
L
----
T
A
H
L
Q
D
V
N
R
E
L
M
S
Q
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
51.22
8%
26
- C2 -
-
3R6N
2
DESP_HUMAN
A:
[1-450]
------------------------
S
G
W
D
E
F
T
K
H
V
T
S
E
C
L
G
W
M
R
Q
Q
R
A
E
M
D
M
-
V
A
W
G
V
-
D
L
A
S
V
E
Q
H
I
N
S
H
R
G
I
H
N
S
I
G
D
Y
R
W
Q
L
D
K
--
I
K
A
D
--
L
R
E
K
S
A
I
Y
Q
L
E
E
E
Y
E
N
L
L
K
A
S
F
E
R
M
-
D
H
L
R
Q
L
Q
N
I
----
I
Q
A
T
S
R
E
I
M
W
I
N
D
C
E
E
--
E
E
L
L
Y
D
W
S
D
K
--
N
T
N
-----
I
A
Q
K
Q
-
E
A
F
S
I
R
M
S
Q
L
E
V
K
E
K
E
L
--
N
K
L
K
Q
----
E
S
D
Q
L
V
L
N
Q
H
-
P
---
A
-----
S
-----
D
K
I
E
A
Y
M
D
T
L
Q
T
Q
W
S
--
W
I
L
Q
I
T
K
C
I
D
V
H
L
K
E
N
A
A
-
Y
F
Q
F
F
E
E
A
Q
S
T
E
A
Y
L
K
G
L
Q
D
S
I
R
K
K
Y
PCDKNMP
L
Q
H
L
L
E
Q
I
K
E
L
E
K
E
R
E
K
I
L
E
Y
K
R
Q
V
Q
N
L
V
N
K
S
K
K
I
V
Q
L
K
P
R
N
P
D
Y
R
S
N
K
P
I
I
L
R
A
L
C
D
Y
K
Q
D
Q
K
I
V
H
K
G
D
E
C
I
L
K
D
N
N
E
R
S
------
K
W
Y
V
T
G
P
G
G
V
D
M
L
V
P
------
S
V
G
L
I
I
P
P
P
N
P
L
A
V
D
L
S
C
K
I
E
Q
Y
Y
E
A
I
L
A
L
W
N
Q
L
Y
I
N
M
K
S
L
V
S
W
H
Y
C
M
I
D
I
E
K
I
R
A
M
T
I
A
K
L
K
T
M
R
Q
E
D
Y
M
K
T
I
A
D
L
E
L
H
Y
Q
E
F
I
R
N
S
Q
GSEM
F
G
D
D
D
K
R
K
I
Q
S
Q
F
T
D
A
Q
K
H
Y
Q
T
L
V
I
Q
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
50.47
11%
22
- C- -
-
4CPC
-
SYCP3_HUMAN
A:
[81-223]
----------------------------------------
I
N
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
-
A
S
L
--
K
T
S
N
Q
K
I
E
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
--
E
Y
S
Q
Q
F
L
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
----
R
I
V
Q
S
Q
R
L
K
T
I
K
Q
L
Y
E
--
Q
F
I
K
S
M
E
E
L
E
--
K
N
H
-----
D
N
L
L
T
-
G
A
Q
N
E
F
K
K
E
M
A
M
L
Q
K
K
I
--
M
M
E
T
Q
----
Q
Q
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.10
22%
123
- C3 -
-
4HSE
-
CLPB_THET8
A:
[259-389]
--------------------------------------------
L
E
S
A
P
E
E
I
D
A
L
E
R
-
K
K
L
Q
L
E
I
E
R
E
A
L
--
S
Q
E
R
L
K
A
I
E
A
E
I
A
K
L
T
E
E
I
A
K
L
R
A
E
W
E
R
E
R
E
I
L
R
K
L
R
E
A
Q
H
R
L
D
E
V
R
-
R
E
I
E
L
A
E
R
Q
--------
Y
D
L
N
R
A
A
E
L
R
Y
G
--
E
L
P
K
L
E
A
E
V
E
--
A
L
S
-----
E
K
L
R
G
-
A
R
F
V
R
L
E
V
T
E
E
D
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
50.08
24%
-11
- C3 -
-
5J0K
-
?
A:
[6-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-----
R
T
E
I
I
-
R
E
L
E
R
S
L
R
E
Q
E
E
L
A
K
R
L
--
K
E
L
L
R
----
E
L
E
R
L
Q
R
E
-------------------
G
S
S
D
E
D
V
R
E
L
L
R
E
I
K
--
E
L
V
E
E
I
E
K
L
A
R
E
Q
K
Y
L
V
E
E
L
K
R
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
49.55
20%
-78
- C3 -
-
1RZJ
5
?
G:
[169-272]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
L
K
Q
I
A
S
K
L
R
E
Q
F
G
N
N
K
T
I
I
F
K
Q
S
S
G
G
D
P
E
I
V
T
H
S
F
N
C
G
G
E
F
F
--------------
Y
C
N
S
T
Q
L
F
N
--
S
T
W
F
N
------------
G
S
D
T
I
T
LPCRI
K
Q
I
I
N
M
W
Q
K
V
G
K
A
M
Y
A
P
P
I
S
G
Q
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
49.20
20%
-89
- C3 -
-
1G9M
6
?
G:
[169-272]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
L
K
Q
I
A
S
K
L
R
E
Q
F
G
N
N
K
T
I
I
F
K
Q
S
S
G
G
D
P
E
I
V
T
H
S
F
N
C
G
G
E
F
F
--------------
Y
C
N
S
T
Q
L
F
N
--
S
T
W
F
N
------------
G
S
D
T
I
T
LPCRI
K
Q
I
I
N
M
W
Q
K
V
G
K
A
M
Y
A
P
P
I
S
G
Q
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
48.82
20%
-75
- C3 -
-
2NXY
8
?
A:
[165-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
L
K
Q
I
A
S
K
L
R
E
Q
F
G
N
N
K
T
I
I
F
K
Q
S
S
G
G
D
P
E
I
V
T
H
S
F
N
C
G
G
E
F
F
--------------
Y
C
N
S
T
Q
L
F
N
--
S
T
W
F
N
------------
G
S
D
T
I
T
L
P
C
R
I
K
Q
I
I
N
M
W
Q
K
V
G
K
A
M
Y
A
P
P
I
S
G
Q
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
47.79
17%
99
- C3 -
-
1QU1
-
?
A:
[34-175]
----------------------------------------------------------------------------------------------------
Q
A
A
D
L
K
S
T
Q
A
A
I
D
Q
I
N
G
K
L
-
N
R
V
I
E
K
T
N
E
----
K
F
H
Q
I
E
--
K
E
F
S
E
V
E
G
--
R
I
Q
D
L
E
K
Y
V
E
--
D
T
K
-----
I
D
L
W
S
-
Y
N
A
E
L
L
V
A
L
E
N
Q
H
T
I
D
L
TD
S
E
M
N
K
----
L
F
E
K
T
R
R
Q
L
G
-
S
F
K
I
Y
-----
H
-----
K
C
D
N
A
C
I
E
S
I
R
N
G
T
Y
--
D
H
D
V
Y
R
D
E
A
L
N
N
R
F
Q
I
K
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------