@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUS1: (2017-12-20 )
MNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAAARVMREFAIKIDVSDIKHLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHHKAMKYAAGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIAELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIALNAGAGIYVAGITKTYAQAVVFAQDIIYGGQTLEKMSVLAEFTKTLKQSQAD
Atome Classification :
(77 SA)
.........10........20........30........40........50........60........70..-...-...80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190....-...200.......210....---...220.......230.......240.......250.......260.......270.-......280.......290.......300......-------.310.......320.......330.......340.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
N
I
Q
Q
A
L
N
H
I
T
KNIHLT
Q
P
Q
M
E
E
I
M
R
S
I
MQGEA
T
E
A
Q
I
G
A
L
M
M
G
L
RMKGE
S
I
D
E
M
T
A
A
A
R
V
M
R
E
F
A
I
K
I
D
V
S
D
-
I
K
H
-
L
V
D
I
VGTGGDG
Q
N
L
F
N
VSTA
S
S
F
V
I
A
AAG
A
T
I
A
KHGNRGVSSKSG
S
S
D
L
L
E
QAG
I
H
L
DL
D
M
Q
Q
T
E
R
C
I
R
EMGV
G
F
L
FAPNH
H
K
A
M
KYAAGPRREL
G
I
R
S
I
F
N
L
LGPLT
N
P
A
G
V
K
R
F
V
I
G
V-F
S
D
E
L
C
R
P
I
A
E
V
M
K
QLGA
E
H
---
V
M
V
V
HSKDGLDEISLAAP
T
T
I
A
ELKDGE
I
T
E
W
TL
N
P
E
DVGIESQTLN
G
L
V
V
ADA
T
A
S
-
L
K
L
I
K
D
A
L
SK
N
K
S
D
I
G
E
K
A
A
N
M
I
A
LNAGA
G
I
Y
V
AG-------
I
T
K
T
Y
A
Q
A
V
V
F
A
Q
D
I
IYGG
Q
T
L
E
K
M
S
V
L
A
E
F
T
K
T
L
K
QSQAD
110
HHSearch
98.15
88%
-131
- C7 -
-
4YI7
1
TRPD_ACIAD
A:
[17-361]
A
N
I
Q
Q
A
L
N
H
I
T
K
N
I
H
L
T
Q
A
Q
M
E
D
V
M
R
S
I
M
Q
G
E
A
T
E
A
Q
I
G
A
L
M
M
G
L
R
M
K
G
E
S
I
D
E
I
T
A
A
A
R
V
M
R
E
L
A
I
K
I
D
V
S
D
-
I
Q
Y
-
L
V
D
I
V
G
T
G
G
D
--
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
R
-------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
D
M
Q
Q
T
E
R
C
I
R
E
M
G
V
G
F
L
F
A
------
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
V
-
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
---
V
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
K
N
G
E
V
T
E
W
V
L
N
P
E
D
V
N
I
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
S
-
L
K
L
I
K
D
A
L
G
R
K
K
S
D
I
G
E
K
A
A
N
M
I
A
L
N
A
G
A
G
I
Y
V
S
G
-------
L
A
T
S
Y
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
L
E
K
M
S
I
L
S
E
F
T
K
A
L
K
E
----
1
PsiBlast_PDB
97.83
88%
-131
- C7 -
-
4YI7
1
TRPD_ACIAD
A:
[18-361]
-
N
I
Q
Q
A
L
N
H
I
T
K
N
I
H
L
T
Q
A
Q
M
E
D
V
M
R
S
I
M
Q
G
E
A
T
E
A
Q
I
G
A
L
M
M
G
L
R
M
K
G
E
S
I
D
E
I
T
A
A
A
R
V
M
R
E
L
A
I
K
I
D
V
S
D
-
I
Q
Y
-
L
V
D
I
V
G
T
G
G
D
--
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
R
-------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
D
M
Q
Q
T
E
R
C
I
R
E
M
G
V
G
F
L
F
A
------
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
V
-
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
---
V
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
K
N
G
E
V
T
E
W
V
L
N
P
E
D
V
N
I
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
S
-
L
K
L
I
K
D
A
L
G
R
K
K
S
D
I
G
E
K
A
A
N
M
I
A
L
N
A
G
A
G
I
Y
V
S
G
-------
L
A
T
S
Y
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
L
E
K
M
S
I
L
S
E
F
T
K
A
L
K
E
----
111
HHSearch
86.45
87%
-125
- C- -
-
4GTN
-
TRPD_ACIAD
A:
[21-365]
A
N
I
Q
Q
A
L
N
H
I
T
K
N
I
H
L
T
Q
A
Q
M
E
D
V
M
R
S
I
M
Q
G
N
A
T
E
A
Q
I
G
A
L
M
M
G
L
R
M
K
G
E
S
I
D
E
I
T
A
A
A
R
V
M
R
E
L
A
I
K
I
D
V
S
D
-
I
Q
Y
-
L
V
D
I
V
G
T
G
G
D
G
Q
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
--------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
D
M
Q
Q
T
E
R
C
I
R
E
M
G
V
G
F
L
F
A
P
---
K
A
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
V
-
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
---
V
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
K
N
G
E
V
T
E
W
V
L
N
P
E
D
V
N
I
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
S
-
L
K
L
I
K
D
A
L
G
R
K
K
S
D
I
G
E
K
A
A
N
M
I
A
L
N
A
G
A
G
I
Y
V
S
G
-------
L
A
T
S
Y
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
L
E
K
M
S
I
L
S
E
F
T
K
A
L
K
E
----
2
PsiBlast_PDB
86.22
88%
-125
- C- -
-
4GTN
-
TRPD_ACIAD
A:
[22-365]
-
N
I
Q
Q
A
L
N
H
I
T
K
N
I
H
L
T
Q
A
Q
M
E
D
V
M
R
S
I
M
Q
G
N
A
T
E
A
Q
I
G
A
L
M
M
G
L
R
M
K
G
E
S
I
D
E
I
T
A
A
A
R
V
M
R
E
L
A
I
K
I
D
V
S
D
-
I
Q
Y
-
L
V
D
I
V
G
T
G
G
D
G
Q
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
--------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
D
M
Q
Q
T
E
R
C
I
R
E
M
G
V
G
F
L
F
A
P
---
K
A
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
V
-
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
---
V
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
K
N
G
E
V
T
E
W
V
L
N
P
E
D
V
N
I
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
S
-
L
K
L
I
K
D
A
L
G
R
K
K
S
D
I
G
E
K
A
A
N
M
I
A
L
N
A
G
A
G
I
Y
V
S
G
-------
L
A
T
S
Y
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
L
E
K
M
S
I
L
S
E
F
T
K
A
L
K
E
----
109
HHSearch
79.87
44%
-124
- C7 -
-
4HKM
2
TRPD_XANCP
B:
[4-343]
I
T
P
Q
Q
A
L
Q
R
T
I
E
H
R
E
I
F
H
D
E
M
V
D
L
M
R
Q
I
M
R
G
E
V
S
D
A
M
V
S
A
I
L
T
G
L
R
V
K
K
E
T
I
G
E
I
A
G
A
A
T
V
M
R
E
F
S
R
R
V
E
V
T
D
-
R
R
H
-
M
V
D
I
V
G
T
-----
H
T
F
N
I
S
T
C
A
M
F
V
A
A
A
G
G
A
K
V
A
K
H
G
N
R
-----
S
G
S
A
D
A
L
E
A
L
G
A
V
I
E
L
Q
P
E
Q
V
A
A
S
L
A
Q
T
G
I
G
F
M
Y
A
P
V
H
H
P
A
M
K
V
V
A
P
V
R
R
E
M
G
V
R
T
I
F
N
I
L
G
P
L
T
N
P
A
G
S
P
N
I
L
M
G
V
-
F
H
P
D
L
V
G
I
Q
A
R
V
L
Q
E
L
G
A
E
R
---
A
L
V
V
W
G
R
D
G
M
D
E
L
S
L
G
A
G
T
L
V
G
E
L
R
D
G
Q
V
H
E
Y
E
V
H
P
E
D
F
G
I
A
M
S
A
S
R
N
L
K
V
A
D
A
A
E
S
-
R
A
M
L
L
Q
V
L
D
N
V
P
----
G
P
A
L
D
I
V
A
L
N
A
G
A
A
L
Y
V
A
G
-------
V
A
D
S
I
A
D
G
I
V
R
A
R
Q
V
L
A
D
G
S
A
R
A
C
L
D
A
Y
V
A
F
T
Q
Q
A
T
-----
3
PsiBlast_PDB
78.04
43%
-136
- C7 -
-
4HKM
1
TRPD_XANCP
A:
[7-340]
---
Q
Q
A
L
Q
R
T
I
E
H
R
E
I
F
H
D
E
M
V
D
L
M
R
Q
I
M
R
G
E
V
S
D
A
M
V
S
A
I
L
T
G
L
R
V
K
K
E
T
I
G
E
I
A
G
A
A
T
V
M
R
E
F
S
R
R
V
E
V
T
D
-
R
R
H
-
M
V
D
I
V
G
T
------
T
F
N
I
S
T
C
A
M
F
V
A
A
A
G
G
A
K
V
A
K
H
G
---------
S
A
D
A
L
E
A
L
G
A
V
I
E
L
Q
P
E
Q
V
A
A
S
L
A
Q
T
G
I
G
F
M
Y
A
P
V
H
H
P
A
M
K
V
V
A
P
V
R
R
E
M
G
V
R
T
I
F
N
I
L
G
P
L
T
N
P
A
G
S
P
N
I
L
M
G
V
-
F
H
P
D
L
V
G
I
Q
A
R
V
L
Q
E
L
G
A
E
R
---
A
L
V
V
W
G
R
D
G
M
D
E
L
S
L
G
A
G
T
L
V
G
E
L
R
D
G
Q
V
H
E
Y
E
V
H
P
E
D
F
G
I
A
M
S
A
---------
A
E
S
-
R
A
M
L
L
Q
V
L
----
D
N
V
P
G
P
A
L
D
I
V
A
L
N
A
G
A
A
L
Y
V
A
G
-------
V
A
D
S
I
A
D
G
I
V
R
A
R
Q
V
L
A
D
G
S
A
R
A
C
L
D
A
Y
V
A
F
T
Q
--------
117
HHSearch
76.56
39%
-116
- C7 -
-
2ELC
2
TRPD_THET8
D:
[2-328]
----
D
A
V
K
K
A
I
L
G
E
V
L
E
E
E
E
A
Y
E
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
--
R
R
P
-
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
-
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
---
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
-
A
A
L
A
R
R
L
L
K
G
E
E
K
---
G
P
L
A
D
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
-------
K
T
P
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
--------
99
Fugue
76.55
36%
-113
- C7 -
-
1KHD
-
?
A:
[12-344]
-
T
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
-
F
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
--------
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
-
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
---
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
-
R
D
I
L
A
R
L
L
---
Q
G
K
G
D
A
A
H
A
R
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
--------
Q
D
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
----------
34
PsiBlast_CBE
74.63
34%
-110
- C7 -
-
3GBR
5
TRPD_SULSO
B:
[2-324]
-
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
G
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
S
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
8
PsiBlast_PDB
74.38
35%
-104
- C7 -
-
1ZXY
1
TRPD_SULSO
A:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
10
PsiBlast_PDB
74.33
35%
-108
- C7 -
-
2GVQ
1
TRPD_SULSO
A:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
---
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
115
HHSearch
74.24
35%
-112
- C7 -
-
1O17
-
TRPD_SULSO
D:
[1-336]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
----
P
N
-
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
-
L
V
N
P
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
-
A
I
K
I
V
R
A
F
L
G
K
D
----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
E
--
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
T
K
L
---
9
PsiBlast_PDB
74.19
35%
-108
- C7 -
-
1ZYK
3
TRPD_SULSO
A:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
26
PsiBlast_CBE
74.10
35%
-104
- C7 -
-
1ZYK
3
TRPD_SULSO
C:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
27
PsiBlast_CBE
74.02
35%
-106
- C7 -
-
1ZYK
3
TRPD_SULSO
B:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
113
HHSearch
73.96
36%
-116
- C7 -
-
1KHD
-
?
C:
[12-344]
-
T
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
-
F
A
D
I
V
G
T
G
-----
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
--------
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
-
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
---
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
-
R
D
I
L
A
R
L
L
Q
G
K
G
D
---
A
A
H
A
R
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
-------
Q
-
D
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
----------
114
HHSearch
73.92
36%
-102
- C7 -
-
1KGZ
1
?
B:
[12-344]
-
T
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
-
F
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
S
V
--
L
A
G
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
-
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
---
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
-
R
D
I
L
A
R
L
L
Q
G
K
G
D
---
A
A
H
A
R
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
-------
Q
-
D
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
----------
22
PsiBlast_CBE
73.80
35%
-110
- C7 -
-
2GVQ
2
TRPD_SULSO
D:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
6
PsiBlast_PDB
73.70
35%
-116
- C7 -
-
1O17
-
TRPD_SULSO
A:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
30
PsiBlast_CBE
73.43
35%
-105
- C7 -
-
1ZXY
1
TRPD_SULSO
B:
[1-324]
M
N
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
D
V
P
N
-----
A
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
P
-
V
A
K
H
G
N
R
A
V
S
G
K
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
-
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
---
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
D
-----
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
-------
R
V
G
D
F
R
E
G
Y
E
Y
A
D
H
L
I
--
E
K
S
L
D
K
L
N
---------------
119
HHSearch
67.96
34%
-38
- C7 -
-
4GIU
7
TRPD_MYCTU
A:
[25-369]
P
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
V
P
D
D
-
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
-
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
-
S
S
---
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
-
A
A
A
V
R
A
V
L
G
G
A
R
----
G
P
V
R
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LSSRAE
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
-------
12
PsiBlast_PDB
62.86
45%
-103
- C7 -
-
2ELC
3
TRPD_THET8
A:
[21-255]
-----------------------
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
R
--
R
P
-
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
-
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
R
G
----
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
-
N
R
V
V
E
V
G
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
--------------------------------------------------------------------------------------------
35
PsiBlast_CBE
62.26
45%
-103
- C7 -
-
2ELC
2
TRPD_THET8
D:
[21-255]
-----------------------
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
R
--
R
P
-
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
-
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
R
G
----
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
-
N
R
V
V
E
V
G
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
--------------------------------------------------------------------------------------------
36
PsiBlast_CBE
61.63
45%
-100
- C7 -
-
2ELC
3
TRPD_THET8
C:
[21-255]
-----------------------
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
R
V
H
R
--
R
P
-
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
-
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
R
G
----
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
-
N
R
V
V
E
V
G
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
--------------------------------------------------------------------------------------------
56
PsiBlast_CBE
57.26
39%
-39
- C7 -
-
3UU1
3
TRPD_MYCTU
C:
[25-296]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
---
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
84
PsiBlast_CBE
57.12
39%
-40
- C7 -
-
4OWM
2
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
--
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
76
PsiBlast_CBE
56.68
39%
-41
- C7 -
-
4OWV
2
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
--
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
80
PsiBlast_CBE
56.65
39%
-32
- C7 -
-
4OWQ
4
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
44
PsiBlast_CBE
56.43
39%
-35
- C7 -
-
5C2L
1
TRPD_MYCTU
A:
[27-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
87
PsiBlast_CBE
56.30
39%
-35
- C7 -
-
4GIU
6
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
65
PsiBlast_CBE
56.21
39%
-34
- C7 -
-
3QSA
1
TRPD_MYCTU
B:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
18
PsiBlast_PDB
56.12
39%
-39
- C7 -
-
4M0R
4
TRPD_MYCTU
A:
[27-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
---
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
50
PsiBlast_CBE
56.10
39%
-39
- C7 -
-
4ZOK
2
TRPD_MYCTA
A:
[27-297]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
15
PsiBlast_PDB
56.10
39%
-38
- C7 -
-
4N8Q
1
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
19
PsiBlast_PDB
56.09
39%
-38
- C7 -
-
4ZOF
2
TRPD_MYCTA
A:
[27-297]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
52
PsiBlast_CBE
56.04
39%
-38
- C7 -
-
4ZOF
2
TRPD_MYCTA
B:
[27-297]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
14
PsiBlast_PDB
56.02
39%
-34
- C7 -
-
4N5V
5
TRPD_MYCTU
A:
[26-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
83
PsiBlast_CBE
56.01
39%
-37
- C7 -
-
4OWN
4
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
--
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
79
PsiBlast_CBE
55.99
39%
-40
- C7 -
-
4OWS
2
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
---
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
---
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
94
PsiBlast_CBE
55.92
39%
-36
- C7 -
-
4X5C
1
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
L
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
20
PsiBlast_PDB
55.90
39%
-36
- C7 -
-
4ZOJ
2
TRPD_MYCTA
A:
[27-298]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
96
PsiBlast_CBE
55.81
39%
-32
- C7 -
-
4X5B
1
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
L
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
97
PsiBlast_CBE
55.79
39%
-36
* C7 *
-
4X59
5
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
A
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
51
PsiBlast_CBE
55.75
39%
-38
- C7 -
-
4ZOJ
2
TRPD_MYCTA
B:
[27-298]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
48
PsiBlast_CBE
55.73
39%
-38
- C7 -
-
5BYT
1
TRPD_MYCTU
A:
[27-297]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
64
PsiBlast_CBE
55.67
39%
-34
- C7 -
-
3R6C
3
TRPD_MYCTU
A:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
86
PsiBlast_CBE
55.53
39%
-39
- C7 -
-
4GIU
5
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
-
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
53
PsiBlast_CBE
55.34
39%
-39
- C7 -
-
4M0R
2
TRPD_MYCTU
B:
[27-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
-----
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
-
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
75
PsiBlast_CBE
55.29
39%
-36
- C7 -
-
3QQS
2
TRPD_MYCTU
A:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
95
PsiBlast_CBE
55.28
39%
-36
- C7 -
-
4X5B
1
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
L
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
82
PsiBlast_CBE
55.26
39%
-36
- C7 -
-
4OWO
5
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
78
PsiBlast_CBE
55.20
39%
-35
- C7 -
-
4OWU
5
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
45
PsiBlast_CBE
55.20
39%
-35
- C7 -
-
5C1R
1
TRPD_MYCTU
B:
[27-295]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
62
PsiBlast_CBE
55.09
39%
-35
- C7 -
-
3R88
1
TRPD_MYCTU
A:
[25-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
85
PsiBlast_CBE
55.08
39%
-34
- C7 -
-
4OWM
3
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
61
PsiBlast_CBE
55.06
39%
-37
- C7 -
-
3R88
2
TRPD_MYCTU
B:
[25-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
54
PsiBlast_CBE
55.05
39%
-46
- C7 -
-
4IJ1
4
TRPD_MYCTU
A:
[27-295]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
----
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
-------
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
92
PsiBlast_CBE
55.04
39%
-36
- C7 -
-
4X58
4
TRPD_MYCTU
A:
[34-301]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
A
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
17
PsiBlast_PDB
55.02
39%
-35
- C7 -
-
4GKM
6
TRPD_MYCTU
A:
[27-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
74
PsiBlast_CBE
54.98
39%
-34
- C7 -
-
3QQS
2
TRPD_MYCTU
B:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
63
PsiBlast_CBE
54.98
39%
-35
- C7 -
-
3R6C
3
TRPD_MYCTU
B:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
16
PsiBlast_PDB
54.95
39%
-32
- C7 -
-
4N93
4
TRPD_MYCTU
A:
[26-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
46
PsiBlast_CBE
54.88
39%
-37
- C7 -
-
5C1R
2
TRPD_MYCTU
A:
[27-296]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
43
PsiBlast_CBE
54.85
39%
-36
- C7 -
-
5C7S
1
TRPD_MYCTU
A:
[27-296]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
77
PsiBlast_CBE
54.77
39%
-34
- C7 -
-
4OWU
3
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
98
PsiBlast_CBE
54.76
39%
-38
- C7 -
-
4X59
2
TRPD_MYCTU
A:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
---
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
A
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
47
PsiBlast_CBE
54.54
39%
-33
- C7 -
-
5BYT
1
TRPD_MYCTU
B:
[27-297]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
39
PsiBlast_CBE
54.54
39%
-35
- C7 -
-
4N93
3
TRPD_MYCTU
B:
[26-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
42
PsiBlast_CBE
54.46
39%
-37
- C7 -
-
5C7S
1
TRPD_MYCTU
B:
[27-298]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
81
PsiBlast_CBE
54.44
39%
-33
- C7 -
-
4OWO
4
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
73
PsiBlast_CBE
54.36
39%
-35
- C7 -
-
3QQS
4
TRPD_MYCTU
C:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
66
PsiBlast_CBE
54.33
39%
-35
- C7 -
-
3QSA
1
TRPD_MYCTU
A:
[25-292]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
49
PsiBlast_CBE
54.32
39%
-37
- C7 -
-
4ZOK
1
TRPD_MYCTA
B:
[27-298]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
-
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
41
PsiBlast_CBE
54.28
39%
-35
- C7 -
-
4N5V
5
TRPD_MYCTU
B:
[26-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
55
PsiBlast_CBE
54.22
39%
-33
- C7 -
-
4GKM
7
TRPD_MYCTU
B:
[27-294]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
93
PsiBlast_CBE
54.02
39%
-39
- C7 -
-
4X5C
1
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
D
G
--
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
L
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------
40
PsiBlast_CBE
53.22
39%
-39
- C7 -
-
4N8Q
1
TRPD_MYCTU
B:
[26-293]
-
S
W
P
Q
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
D
T
-
V
P
D
D
A
V
D
V
V
G
T
G
G
----
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
-----
L
A
E
V
M
A
G
V
F
A
A
R
RSS
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
----------------------------------------------------------------------------------------