@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUT2: (2017-12-20 )
MTTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVIFMRAAGCAINDFADRKVDGHVERTKTRPLATGVIRAREAAYVFLGLVLASACLLFFLPIETFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMAFTAVGKTPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILFPWAIIALVVVAFDFIYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI
Atome Classification :
(20 SA)
-------------------------------.........10...-----------...----..20........----------30....--...------.40.---..---.....50.-----......---------------------------.60...---..--.-..70........-80.--.------------.------..-----...90........-100......--.110------------...---------......------120........------.130-....------..---..140....--.-----.-----------..150---....----------.....160-..--------..--------.--....--------170......--.------------------180.....-----..190...------------....200.......-----210..-....-----..220------.--..-....230.--..---------------....240.--------------......250-------------.-...-----...260..-----...--..270.......280.......290--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------MTTAT
G
T
T
W
R
Q
R
L
E
-----------
A
Y
Y
----
Y
L
C
RFDKPIGT
E
----------
L
V
F
W
P
T
--
M
W
A
------
L
W
V
A
---SK---GIP
N
L
G
I
L
-----
F
V
M
I
L
G
---------------------------
V
I
F
M
RA---AG--C-AINDFADRKVDG-H
V
E
--R------------T------KT-----RPL
A
T
G
V
I
R
A
R
E
A
-
A
Y
V
F
L
G
L
V
L
--
A
S
--------------
A
C
L
---------
L
F
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L
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I
------
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W
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A
------
L
F
L
--
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F
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P
F
---
M
K
R
-YTNL
P
--
Q
-----
V
-----------
F
L
G-----AAFS----------WSI
P
M
A
---
F
T--------AV--------G--KTPD--------
L
T
C
W
L
L
YFG--N------------------
L
A
W
T
V
A
YD-----
T
Q
Y
A
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TDR------------
E
Y
D
L
K
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K
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T
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-----
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-----
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A
L
L
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------
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I
S
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A
L
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L
---------------
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N
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L
F
P
W
A
--------------
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A
L
V
V
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A
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-------------
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-
F
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-----
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T
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KTKDR-----NP
Q
--
V
C
F
W
A
FRHN
R
W
V
G
L
I
I
F
L
G
I
F
L
NFI--------------------------------------
27
Fugue
89.80
20%
-165
- C9 -
-
4TQ3
1
?
A:
[15-301]
--------------------------------------------
S
-----------
K
Y
L
----
R
L
L
R
---
P
V
A
W
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----------
C
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F
G
F
G
---
I
T
---
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N
A
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-----
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L
G
L
L
S
---------------------------
F
A
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W
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A
---
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------------
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-----
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--------------
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--
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--------
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F
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A
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Y
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K
K
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N
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----
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A
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F
--
L
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---------------
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-
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--------------
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I
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P
L
I
I
A
Y
-------------
T
-
L
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-----
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F
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N
S
R
W
DGEKL
N
V
S
--
P
N
L
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L
T
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F
G
I
I
S
A
L
F
I
A
Y
G
F
A
V
I
S
V
--------------------------------------
19
HHSearch
85.79
20%
-138
* C9 *
-
4TQ3
1
?
A:
[15-262]
--------------------------------------------
S
-----------
K
Y
L
----
R
L
L
R
P
V
A
---
W
L
----------
C
F
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------
F
G
F
G
---
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---
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N
A
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-----
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L
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L
L
S
---------------------------
F
A
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W
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A
---
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--
F
-
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N
A
L
Y
D
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D
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--
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S
M
-----
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L
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T
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E
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S
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A
-
W
L
Y
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A
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--------------
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----------
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Y
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G
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--
A
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-----------
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I
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F
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A
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-----
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P
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A
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S
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------------
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F
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K
K
A
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L
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N
T
P
V
F
-----
F
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-
P
E
R
A
L
K
S
-----
L
Y
P
L
S
------
A
--
I
T
-
V
I
L
W
A
Y
V
F
--
L
M
---------------
A
E
R
I
E
I
K
V
--------------
I
S
P
L
-
I
I
A
Y
-------------
T
-
L
I
Y
-----
T
F
-------------------------------------------------------------------------------
26
Fugue
85.63
24%
-
- C9 -
-
4OD4
-
?
A:
[3-277]
----------------------------------------------------------------------
L
V
R
I
E
----------
H
T
I
F
S
L
--
P
F
A
------
Y
V
G
A
L
L
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S
R
---
Y
P
F
T
L
A
D
A
-----
I
L
M
A
A
A
---------------------------
V
V
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L
R
M
---
A
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--
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-
A
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------------
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--------------
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L
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--
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-----
L
-----------
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L
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-----
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L
G
----------
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V
F
G
G
---
A
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--------
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A
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L
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L
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--------
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L
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A
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D
-----
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I
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M
D
I
------------
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F
D
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L
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P
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-----
L
G
-
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K
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A
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A
-----
A
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L
A
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------
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--
A
A
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A
V
A
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F
I
A
G
--
V
E
---------------
A
Y
G
L
G
A
I
A
--------------
T
V
S
T
A
L
T
A
L
-------------
V
-
I
I
L
-----
V
Q
A
M
A
W
L
G
-----
R
V
K
--
E
S
F
N
L
---
N
L
A
V
P
I
I
I
G
A
G
I
I
V
D
M
L
--------------------------------------
20
HHSearch
84.19
20%
-155
- C9 -
-
4TQ4
1
?
D:
[14-262]
-------------------------------------------
P
S
-----------
K
Y
L
----
R
L
L
R
P
V
A
---
W
L
----------
C
F
L
L
P
Y
--
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------
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G
F
G
---
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---
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N
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A
-----
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L
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L
L
S
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A
F
W
M
A
---
F
S
--
F
-
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N
A
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R
D
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R
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D
--
G
------------
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VKDLNL
S
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-----
Q
P
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T
G
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V
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A
-
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A
F
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A
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--------------
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A
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---------
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A
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------
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--
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F
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A
M
L
G
A
------
N
I
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--
G
Y
V
Y
------
S
A
PPR
F
K
A
-
W
P
V
M
D
--
V
-----
I
-----------
C
N
A
-----
L
A
A
V
----------
L
A
F
Y
A
G
---
L
S
--------
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G
--------
G
--
A
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V
-----------
P
I
A
I
Y
P
A
--
A
------------------
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F
L
A
A
T
F
Y
-----
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P
T
A
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S
D
Y
------------
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F
D
K
K
A
G
L
K
N
T
P
V
F
-----
F
G
-
P
E
R
A
L
K
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-----
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Y
P
L
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------
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--
I
T
-
V
I
L
W
A
Y
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F
--
L
M
---------------
A
E
R
I
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I
K
V
--------------
I
S
P
L
-
I
I
A
Y
-------------
T
-
L
I
Y
-----
T
F
-------------------------------------------------------------------------------
18
HHSearch
81.90
21%
-
- C9 -
-
4OD4
-
?
F:
[3-276]
----------------------------------------------------------------
L
V
R
I
E
H
T
I
F
-------------
S
L
P
F
A
--
Y
V
G
------
A
L
L
S
---
R
Y
----
P
F
T
L
A
D
A
-----
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
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D
R
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L
N
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--
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------------
T
------
A
K
-----
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V
V
G
A
V
S
L
R
E
A
-
W
A
L
V
A
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G
S
A
--
I
Y
--------------
F
A
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---------
A
A
L
L
N
T
------
Y
--
A
L
L
L
S
P
L
V
------
L
A
I
--
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
-----
I
V
L
G
----------
S
V
V
F
G
G
---
A
V
--------
A
A
--------
S
--
G
D
E
A
SSLGEVLR
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
-
P
K
G
A
L
A
A
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L
A
M
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------
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A
A
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V
A
L
F
I
A
G
V
--
E
A
---------------
Y
G
L
G
A
I
A
T
--------------
V
S
T
A
-
L
T
A
L
-------------
V
I
I
L
V
-----
Q
A
M
----
A
-----
W
L
G
--
R
V
K
E
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F
N
L
N
L
A
V
P
I
I
I
G
A
G
I
I
V
D
M
---------------------------------------
3
PsiBlast_PDB
77.95
27%
-145
- C9 -
-
4TQ5
1
?
A:
[54-233]
----------------------------------------------------------------------------------------------------------------------------------
L
L
S
---------------------------
F
A
F
W
M
A
---
F
S
--
F
-
T
I
N
A
L
Y
D
R
--------------------------------LNLSM
Q
P
L
V
T
G
E
I
S
V
R
E
A
-
W
L
Y
C
I
A
F
L
A
--
L
S
--------------
L
A
T
---------
A
A
A
I
N
E
------
K
--
F
F
L
A
M
L
G
A
------
N
I
I
--
G
Y
V
Y
------
S
A
---
P
P
R
-
F
K
A
W
P
V
M
D
-----
V
-----------
I
C
N
-----
A
L
A
A
----------
V
L
A
F
Y
A
---
G
L
--------
S
I
--------
G
GA
E
V
P
I
--------
A
I
Y
P
A
A
F
F
----------------------
L
A
A
T
F
Y
I
P
-----
T
--
A
V
S
D
Y
------------
E
F
D
K
K
A
G
L
K
N
T
P
V
F
-----
F
G
P
E
R
-
A
L
K
S
-----
L
Y
P
L
S
------
A
--
I
T
-
V
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
75.77
31%
-137
- C9 -
-
4OD5
3
?
F:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
YF
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
AI
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
IVLGS
V
V
F
G
----------
G
A
V
A
A
S
GDE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
75.52
31%
-137
- C9 -
-
4OD5
2
?
B:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
YF
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
AI
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
IVLGS
V
V
F
G
----------
G
A
V
A
A
S
GDE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
75.51
31%
-137
- C9 -
-
4OD5
2
?
A:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
Y
F
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
A
I
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
I
V
L
G
S
V
V
F
G
----------
G
A
V
A
A
S
G
DE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
75.43
31%
-137
- C9 -
-
4OD5
2
?
D:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
YF
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
AI
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
IVLGS
V
V
F
G
----------
G
A
V
A
A
S
GDE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
75.35
31%
-137
- C9 -
-
4OD5
2
?
E:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
YF
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
AI
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
IVLGS
V
V
F
G
----------
G
A
V
A
A
S
GDE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
75.02
31%
-137
- C9 -
-
4OD5
2
?
C:
[52-218]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
YF
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
AI
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
IVLGS
V
V
F
G
----------
G
A
V
A
A
S
GDE
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
72.88
31%
-
- C9 -
-
4OD4
-
?
A:
[33-199]
-------------------------------------------------------------------------------------------------------------------------------
I
L
M
A
A
A
---------------------------
V
V
G
L
R
M
---
A
G
--
M
-
A
Y
N
N
I
A
D
L
D
I
D
R
-
L
N
P
--
R
------------
T
------
A
K
-----
R
P
L
V
V
G
A
V
S
L
R
E
A
W
A
L
V
A
A
G
S
A
I
Y
F
A
S
--------------
A
A
L
---------
L
-----------
N
--
T
Y
A
L
L
L
S
P
------
L
V
L
A
I
A
L
T
Y
------
P
H
---
A
K
R
-
L
H
P
L
P
--
H
-----
L
-----------
H
L
G
I
V
L
G
S
V
V
F
G
----------
G
A
V
A
A
S
G
D
E
A
S
--------
S
L
--------
G
--
E
V
L
R
--------
S
V
P
W
L
Y
V
A
A
--
V
------------------
S
L
W
V
A
G
F
D
-----
T
I
Y
S
I
M
D
I
------------
D
F
D
R
S
H
G
L
G
S
I
P
A
L
-----
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
70.08
19%
-93
- C2 -
-
4QFR
3
AAKG1_RAT
C:
[28-322]
----------------------------------
Y
T
T
F
M
K
S
H
R
C
Y
-----------
D
L
I
PT
S
S
K
L
V
V
F
D
T
S
L
Q
V
K
----------
K
A
F
F
A
L
--
V
T
N
GVR
A
A
P
L
W
D
S
---
K
K
---
Q
-
S
F
V
G
M
L
-----
T
I
T
D
F
I
---------------------------
N
I
L
H
R
Y
YKS
A
L
--
V
-
Q
I
Y
E
L
E
E
H
K
I
E
T
-
W
R
E
--
V
------------
Y
------
L
Q
-----
D
S
F
K
P
L
V
C
I
S
P
N
A
-
S
-
L
F
D
A
V
S
S
--
L
I
--------------
R
N
K
---------
I
H
R
L
P
V
I
D
PESG
N
--
T
L
Y
I
L
T
H
K
------
R
I
L
--
K
F
L
K
------
L
F
---
I
----
T
S
L
E
--
E
-----
L
-----------
Q
I
G
-----
T
Y
A
N
----------
I
A
M
-----------------
V
--------
R
--
T
T
T
P
--------
V
Y
V
A
L
G
I
F
V
Q
H
R
------------------
V
S
A
L
P
V
V
D
-----
E
K
G
R
V
V
D
I
------------
Y
S
K
F
D
V
I
N
L
A
A
E
K
T
-----
Y
N
-
N
L
-
D
V
S
V
-----
T
K
A
L
Q
------
H
RV
L
K
-
C
Y
L
H
E
T
L
E
--
A
I
---------------
I
N
R
L
V
E
A
E
--------------
V
H
R
L
V
V
V
D
------------------------------------------------
E
H
D
V
V
K
G
I
V
S
L
S
D
I
L
Q
A
L
V
--------------------------------------
33
Fugue
69.42
19%
-54
- C5 -
-
4FDT
1
?
A:
[21-425]
-------------------------------
M
Q
T
K
I
Q
K
Y
A
G
T
A
M
P
YPNRTDGMTPF
Y
I
N
----
H
L
G
R
H
G
A
R
F
P
T
S
----------
R
K
A
L
D
K
--
V
E
K
------
V
L
V
S
---
A
Q
Q
E
N
G
L
T
S
E
G
M
A
-----
L
L
S
M
I
R
---------------------------
R
L
S
R
L
F
---
D
G
QW
G
-
K
L
S
K
L
G
E
T
E
Q
E
G
-
I
A
G
--
R
M
I
R
N
YPQLFSNS
A
------
K
I
-----
E
A
I
A
T
Y
V
P
R
S
I
N
S
-
M
D
A
F
L
S
C
M
I
--
R
H
NPA
L
Q
V
Q
R
S
E
G
KQY
N
H
I
---------
L
R
F
F
D
L
------
N
--
K
S
Y
V
N
Y
K
E
KG
D
W
L
P
I
Y
K
--
A
F
V
H
K
K
ISP
V
P
I
---
M
K
K
-
F
L
L
N
P
--
E
-----
Q
-----------
Y
L
D
-----
K
E
A
E
----------
E
F
V
M
A
L
---
F
S
--------
V
A
--------
A
--
I
L
P
D
--------
T
S
I
P
L
------
N
------------------
L
E
D
L
F
T
L
D
-----
E
W
H
R
Y
W
Q
T
------------
Q
N
L
R
Q
Y
M
S
K
S
S
A
P
V
-----
G
K
-
M
L
-
P
V
A
I
A
W
P
L
L
S
E
F
I
R
------
S
--
A
Q
-
E
V
I
S
G
K
S
D
--
Y
Q
---------------
A
N
F
R
F
A
H
A
--------------
E
T
V
I
P
F
V
S
L
M
GIEKTDVQVCRP
D
-
S
V
S
-----
V
Y
W
K
D
Y
E
I
-----
S
P
M
A
A
N
V
Q
W
L
F
Y
R
D
R
--
D
Q
R
I
W
V
K
I
L
L
N
E
E
A
A
A
L
PISTACFPYYS
W
E
K
T
R
I
F
F
N
Q
R
I
E
M
A
K
K
T
L
S
V
F
N
5
PsiBlast_PDB
65.99
25%
-77
- C9 -
-
4TQ4
1
?
A:
[67-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
A
L
Y
D
R
D
V
D
R
L
H
D
G
--
R
------------
V
------
K
D
LNLSM
Q
P
L
V
T
G
E
I
S
V
R
E
A
-
W
L
Y
C
I
A
F
L
A
--
L
S
--------------
L
A
T
---------
A
A
A
I
N
E
------
K
--
F
F
L
A
M
L
G
A
------
N
I
I
--
G
Y
V
Y
------
S
A
---
P
P
R
-
F
K
A
W
P
V
M
D
-----
V
-----------
I
C
N
-----
A
L
A
A
----------
V
L
A
F
Y
A
---
G
L
--------
S
I
--------
G
--
G
A
E
----------
V
P
I
A
I
Y
P
A
--
A
------------------
F
F
L
A
A
T
F
Y
-----
I
P
T
A
V
S
D
Y
------------
E
F
D
K
K
A
G
L
K
N
T
P
V
F
-----
F
G
P
E
R
-
A
L
K
S
-----
L
Y
P
L
S
------
A
--
I
T
-
V
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.23
25%
-87
- C9 -
-
4TQ3
1
?
A:
[67-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
A
L
Y
D
R
D
V
D
R
L
H
D
G
------------------------LNLSM
Q
P
L
V
T
G
E
I
S
V
R
E
A
-
W
L
Y
C
I
A
F
L
A
--
L
S
--------------
L
A
T
---------
A
A
A
I
N
E
------
K
--
F
F
L
A
M
L
G
A
------
N
I
I
--
G
Y
V
Y
------
S
A
---
P
P
R
-
F
K
A
W
P
V
M
D
-----
V
-----------
I
C
N
-----
A
L
A
A
----------
V
L
A
F
Y
A
---
G
L
--------
S
I
--------
G
--
G
A
E
----------
V
P
I
A
I
Y
P
A
--
A
------------------
F
F
L
A
A
T
F
Y
-----
I
P
T
A
V
S
D
Y
------------
E
F
D
K
K
A
G
L
K
N
T
P
V
F
-----
F
G
P
E
R
-
A
L
K
S
-----
L
Y
P
L
S
------
A
--
I
T
-
V
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
60.46
19%
-37
- C3 -
-
5I99
1
A:
[1-398]
------------------------PGSAPDF
S
R
N
P
M
K
K
M
V
Q
V
Q
V
G
-----------
S
L
V
----
I
L
D
C
K
P
R
A
S
P
R
A
----------
L
S
F
W
K
K
GD
M
M
V
------
R
E
Q
A
---
R
V
---
S
F
L
N
D
G
G
L
-----
K
I
M
N
V
T
---------------------------
K
A
D
A
G
T
---
Y
T
--
C
T
A
E
N
Q
F
G
K
A
N
G
T
T
-
H
L
V
--
V
------------
T
------
E
P
---------
T
R
I
I
L
A
P
S
N
-
M
D
V
A
V
G
E
S
V
--
I
L
--------------
P
C
Q
---------
V
Q
H
D
P
L
------
L
D
I
M
F
A
W
Y
F
N
G
------------
A
L
T
------
D
F
---
K
K
D
-
G
S
H
F
E
--
K
-----
V
GGSSSG
D
L
M
I
R
N
I
Q
-----
L
K
H
S
----------
G
K
Y
V
C
M
---
V
Q
--------
T
G
--------
V
--
D
S
V
S
--------
S
A
A
E
L
I
V
R
G
--
S
P
GPPEN
V
K
V
D
EITDT
T
A
Q
L
S
W
T
E
G
T
D
SHSPV
I
S
Y
A
V
Q
A
R
T
PFSV
G
W
Q
S
V
R
T
V
P
E
V
I
D
G
K
T
H
T
A
T
V
V
ELNP
W
V
-
E
Y
-
E
F
R
I
-----
V
A
S
N
K
IGGGEP
S
--
L
P
-
S
E
K
V
R
T
E
E
--
A
A
PEIAPSE
V
S
G
G
G
G
S
R
S
E
L
V
I
T
W
D
P
V
P
EELQNGGG
F
G
Y
V
V
A
F
R
P
L
G
V
-------------
T
-
T
W
I
-----
Q
T
V
V
T
S
P
D
-----
N
P
R
--
Y
V
F
R
N
E
S
I
V
P
F
S
P
Y
E
V
K
V
G
V
Y
N
N
K
G
E
G
P
F
S
P
V
T
T
V
F
S
A
EEE----------------------
35
Fugue
54.52
14%
-77
- C6 -
-
3CM8
-
?
A:
[12-471]
IEPFLKTTPR
P
L
R
L
P
D
G
P
P
C
S
Q
R
S
KFLLMDA
L
K
L
S
I
E
I
P
L
Y
D
A
I
K
-----------
C
M
K
----
T
F
F
G
W
K
E
P
N
I
V
K
PHEKGI
N
P
N
Y
L
L
A
W
K
Q
--
V
L
A
------
E
L
Q
D
I
EN
E
E
---
K
I
P
K
T
K
N
M
RKT
S
Q
L
K
W
A
L
G
ENMAPEKVDFED
C
K
D
V
SEP
K
P
R
S
L
AS
W
I
Q
S
E
F
N
---
K
A
--
C
-
E
L
T
D
S
S
W
I
E
L
D
E
-
I
I
A
--
S
------------
M
------
R
R
-----
N
Y
F
T
A
E
V
S
H
C
R
A
T
-
E
Y
I
M
K
G
V
Y
I
--
N
T
--------------
A
L
L
N
A
S
C
A
AMDD
F
Q
L
I
P
M
------
I
--
S
K
C
R
T
K
E
G
------
R
R
K
--
T
N
L
Y
------
G
F
---
I
I
K
G
R
S
H
L
R
--
N
DT
D
V
V
N
-----------
F
V
S
-----
M
E
F
S
LTDPRLEPHK
W
E
K
Y
C
V
---
L
E
I
G
D
M
L
L
R
T
A
I
--------
G
Q
-
V
S
R
P
--------
M
F
L
Y
V
R
T
N
G
--
T
------------------
S
K
I
K
M
K
W
G
-----
M
E
M
R
R
C
L
L
------------
Q
S
L
Q
Q
I
E
S
M
I
E
A
E
S
-----
S
V
-
K
E
-
K
D
M
T
-----
K
E
F
F
E
------
N
--
K
S
E
T
W
P
I
G
E
S
P
K
G
M
E
---------------
E
G
S
I
G
K
V
C
--------------
R
T
L
L
A
K
S
V
F
-------------
N
-
S
L
Y
AS
P
Q
L
E
G
F
S
A
E
S
R
-----
K
L
L
--
L
I
V
Q
A
L
R
D
N
L
E
P
G
T
F
D
L
G
G
L
Y
E
A
I
E
E
C
LIND
P
W
V
L
L
N
A
S
W
F
N
S
F
L
T
H
A
L
K-------------
12
PsiBlast_PDB
43.38
27%
-119
- C4 -
-
1TUE
-
VE1_HPV18
A:
[466-570]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
L
K
S
F
L
K
G
T
P
--
K
K
--------------
N
C
L
---------
V
F
C
G
P
A
------
N
--
T
G
K
S
Y
F
G
M
------
S
F
I
--
H
F
I
Q
------
G
A
---
V
I
S
-
F
V
N
S
T
--
S
-----
H
-----------
F
---------------------
W
L
E
P
L
T
---
D
T
--------
K
V
--------
A
--
M
L
D
D
AT------
T
T
C
W
T
Y
F
----
D
------------------
T
Y
M
R
N
A
L
D
-----
G
N
P
I
S
I
D
----------------
P
L
I
Q
L
K
C
P
P
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------