@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VUX3: (2017-12-21 )
MTDALVLRDLSKTYRNGFQALKGINLTVPEGEFYALLGPNGAGKSTTIGIISSLTKKTSGTVEIFGHNLDTHPSLAKQQLGVVPQEFNFGQFEKAFDILVTQAGYYGIHRKIAEKRAEHYLEKLGLWEKRNIQARMLSGGMKRRLMIARAMMHEPKLLILDEPTAGVDIELRRSMWDFLTEMNENGTSIILTTHYLEEAEMLCRQIAIIDRGVIKEDTSMKSFLNQLSEESFIFDLAEPIAPLQLNIIGVKFNLIDGSTLEVTMDKAHTLNDLFQLLESQGIRVRSMRNKSNRLEELFVKMVEKNLEGAAK
Atome Classification :
(21 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.....-.---..20........30........40........50........60........----70----.----..-----.....80.......-.90..-......---100.......110.......120..--.....130.......140.......150.......160.......170.......180-..-.-....190.......200.......210-.......220.......230.--......240---------------------.......250.......260...-....270.....--..280.......290.......300.......310-----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MT
D
A
L
V
L
R
D
L
S
K
T
Y
R
N
-
G
---
F
Q
A
LKG
I
N
L
TVPEG
E
F
Y
A
L
LGPNGAGKS
T
T
I
G
I
I
S
S
L
T
KKTS
G
T
V
E
I
F
GHNL----DT----
H
----
P
S
-----
L
A
K
Q
Q
LGVVPQEFN-
F
G
Q
F
E
-
K
A
F
D
I
L
---VTQAG
Y
Y
G
I
H
R
K
I
A
E
K
R
A
E
H
Y
L
E
KL--GLWEKRN
I
Q
A
R
M
L
SG
G
M
K
R
R
L
M
I
A
R
A
M
MHEP
K
L
L
I
L
DEPTAGV
D
I
E
L
R
R
S
M
W
D
F
L
T
E
M-NE-N-G
T
S
I
I
L
T
T
H
Y
L
E
E
A
E
M
L
C
R
Q
I
A
I
IDRG-VIKE
D
T
S
M
K
S
F
L
N
Q
LSEE
S
F
I
--
F
D
L
AEPIA
P
---------------------
L
Q
L
N
I
I
G
V
K
F
N
LIDG
S
T
L
E
V
T
MD-KAH
T
L
N
D
L
F
Q
L
L
--
E
SQG
I
R
V
R
S
M
RNKS
N
R
L
E
E
L
F
V
K
M
V
E
K
N
LEGAAK------------------------------------------
1
PsiBlast_PDB
80.55
31%
-94
- C1 -
-
4YER
2
?
A:
[4-307]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
I
V
V
E
N
L
V
K
K
F
G
D
-----
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
H
D
V
----
L
K
----
E
----
P
R
-----
E
V
R
R
K
I
G
I
V
F
Q
D
Q
S
-
L
D
R
E
L
-
T
A
Y
E
N
M
---
Y
I
H
G
K
I
Y
G
Y
G
G
E
K
L
K
K
R
I
L
E
L
L
E
F
V
--
E
L
L
E
F
K
D
K
P
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
-
H
-
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
-
K
I
I
A
L
G
T
P
T
E
L
K
R
M
V
G
K
E
I
I
Y
--
V
R
-------------------------------
D
F
I
E
S
C
R
K
L
P
D
G
R
L
E
L
N
V
E
D
---------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
F
L
H
L
T
G
R
E
L
-----------------------------------------------
2
PsiBlast_PDB
80.07
37%
-129
- C1 -
-
1VPL
-
?
A:
[15-233]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
V
V
K
D
L
R
K
R
I
G
K
-
K
----
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
K
N
V
----
V
E
----
E
----
P
H
-----
E
V
R
K
L
I
S
Y
L
P
E
E
A
G
-
A
Y
R
N
M
-
Q
G
I
E
Y
L
---
R
F
V
A
G
F
Y
A
S
S
S
S
E
I
E
E
M
V
E
R
A
T
E
I
A
--
G
L
G
E
K
I
K
D
R
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
-
S
Q
-
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
-
T
I
V
E
T
G
T
V
E
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------
64
HHSearch
72.12
27%
-116
- C1 -
-
2AWN
1
MALK_ECOLI
B:
[2-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
-
E
---
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
M
----
N
D
----
T
----
P
------
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
-
S
V
A
E
N
M
---
S
F
G
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
--
Q
L
A
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
-
H
K
R
L
-
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
-
R
V
A
Q
V
G
K
P
L
E
L
Y
H
----------------------------------------------------------------------------------------------------------------------------------------------------------
82
Fugue
70.43
24%
-3
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
TTLS
E
S
----
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
-
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
--
K
F
I
Q
S
T
L
H
L
DIPEDYQERLQAEPFTDCVPM
L
R
L
E
F
T
G
Q
S
V
D
A
P
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
GG
V
K
F
G
I
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
I
A
W
L
Q
E
H
H
V
K
V
E
V
-------------------------------------------
63
HHSearch
69.86
27%
-118
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[2-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
-
E
---
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
R
M
----
N
D
----
T
----
P
------
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
-
S
V
A
E
N
M
---
S
F
G
L
K
L
A
G
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
--
Q
L
A
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
-
H
K
R
L
-
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
-
R
V
A
Q
V
G
K
P
L
E
L
Y
H
----------------------------------------------------------------------------------------------------------------------------------------------------------
89
Fugue
66.73
28%
-3
- C1 -
-
3B60
2
MSBA_SALTY
A:
[10-581]
W
Q
T
F
R
R
L
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
LKPLLDDGFGKTDRSVLLW
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
M
G
MPVAFFDKQS
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
FYYS
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
R
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
KEVLIFGG
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
I
Q
L
I
A
S
L
A
L
A
F
V
L
Y
A
A
S
FPSVMDSLT
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
SEQEK
D
E
G
K
RVIDR
A
T
G
D
L
E
F
R
N
V
T
F
T
Y
P
G
R
E
---
V
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
D
G
H
D
L
R---
E
Y
----
T
----
L
A
-----
S
L
R
N
Q
V
A
L
V
S
Q
N
V
H
-
L
F
N
D
T
-
V
A
N
N
I
A
YAR
T
E
E
Y
S
R
E
Q
I
E
E
A
A
R
M
A
Y
A
M
D
F
I
N
K
M
DN
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
-
Q
K
-
N
-
R
T
S
L
V
I
A
-
H
R
L
S
T
I
E
Q
-
A
D
E
I
V
V
V
E
D
G
-
I
I
V
E
R
G
T
H
S
E
L
L
A
Q
--------------------------------------------------------------------
H
G
V
Y
A
Q
L
--
H
K
M
Q
F
G
----------------------------------------------------------------------
85
Fugue
66.11
21%
-71
- C1 -
-
1Z47
-
?
A:
[11-355]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
-
G
---
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
----
T
D
----
L
----
P
P
-----
Q
K
R
N
-
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
-
T
V
Y
D
N
V
---
S
F
G
L
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
--
R
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
-
H
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
-
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
-
P
G
T
L
F
V
--
A
S
F
I
G
E
S
N
V
---------------------
W
T
R
A
V
Q
N
G
R
I
E
V
---
A
G
A
A
L
P
V
D
-
P
A
V
S
E
G
S
E
V
A
V
------
V
V
R
P
K
D
V
E
L
Q
P
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
81
HHSearch
65.68
30%
-6
* C1 *
-
3TUI
1
METN_ECOLI
C:
[23-253]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
----
L
SESE
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
-
E
L
I
E
Q
D
T
V
S
E
V
F
S
----------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.48
31%
2
- C1 -
-
3TUI
1
METN_ECOLI
C:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
69
HHSearch
63.86
30%
-32
- C1 -
-
5X3X
-
CBIO_RHOCB
B:
[1-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
I
L
A
A
E
A
L
T
Y
A
F
P
G
-
G
---
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
G
T
A
T
----
G
H
SRK-
D
----
L
T
-----
G
W
R
R
R
V
G
L
V
L
Q
D
A
D
D
Q
L
F
A
T
-
T
V
F
E
D
V
---
S
F
G
P
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
--
S
I
S
D
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
E
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
R
G
L
-
R
A
-
A
-
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
-
R
V
L
A
E
G
A
A
E
A
V
L
S
D
R
A
-------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
63.80
31%
1
- C1 -
-
3TUZ
1
METN_ECOLI
C:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.74
35%
-8
- C1 -
-
2PCL
5
LOLD_AQUAE
A:
[2-224]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
L
R
A
E
N
I
K
K
V
I
R
--
G
---
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
----
D
Y
----
T
----
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
-
F
H
-
Y
L
I
P
E
L
T
A
L
E
N
V
---
I
V
P
M
L
K
M
G
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
--
G
L
G
D
K
L
S
R
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
-
N
E
-
G
-
G
T
S
I
V
M
V
T
H
E
R
E
L
A
E
L
T
H
R
T
L
E
M
K
D
G
K
-
V
V
G
E
I
T
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------
73
HHSearch
63.59
30%
-31
- C1 -
-
5X40
2
CBIO_RHOCB
A:
[13-244]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
P
I
L
A
A
E
A
L
T
Y
A
F
P
G
-
G
---
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
G
T
A
T
----
G
H
S
R
K
-
D
----
L
T
-----
G
W
R
R
R
V
G
L
V
L
Q
D
A
D
D
Q
L
F
A
T
-
T
V
F
E
D
V
---
S
F
G
P
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
--
S
I
S
D
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
Q
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
R
G
L
-
R
A
-
A
-
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
-
R
V
L
A
E
G
A
A
E
A
V
L
S
D
R
A
-------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
62.63
31%
6
- C1 -
-
3TUI
1
METN_ECOLI
H:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
80
HHSearch
62.44
26%
-98
- C1 -
-
1Z47
-
?
A:
[14-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
E
F
V
G
V
E
K
I
Y
P
G
-
G
---
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
----
T
D
----
L
----
P
------
P
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
-
T
V
Y
D
N
V
---
S
F
G
L
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
--
R
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
-
H
D
E
M
-
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
-
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
---------------------------------------------------------------------------------------------------------------------------------------------------------
74
HHSearch
62.37
26%
-100
- C1 -
-
1Z47
-
?
B:
[14-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
E
F
V
G
V
E
K
I
Y
P
G
-
G
---
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
----
T
D
----
L
----
P
------
P
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
-
T
V
Y
D
N
V
---
S
F
G
L
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
--
R
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
-
H
D
E
M
-
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
-
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
---------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
62.11
31%
2
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
68
HHSearch
62.07
26%
-101
- C1 -
-
2YYZ
1
?
A:
[2-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
I
R
V
V
N
L
K
K
Y
F
-
G
-
K
---
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
D
D
V
L
V
----
N
D
----
I
----
P
------
P
K
Y
R
E
V
G
M
V
F
Q
N
Y
A
-
L
Y
P
H
M
-
T
V
F
E
N
I
---
A
F
P
L
R
A
R
R
I
S
K
D
E
V
E
K
R
V
V
E
I
A
R
K
L
--
L
I
D
N
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
-
Q
Q
E
L
-
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
-
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
---------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
61.99
31%
9
- C1 -
-
3TUI
1
METN_ECOLI
D:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
61.88
31%
9
- C1 -
-
3TUZ
1
METN_ECOLI
D:
[27-252]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
I
T
K
V
F
H
Q
-
G
TRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
T
LSES
E
----
L
T
-----
K
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
-
T
V
F
G
N
V
---
A
L
P
L
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
--
G
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
45.68
32%
-4
- C1 -
-
4YER
2
?
A:
[2-308]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
D
I
I
V
V
E
N
L
V
K
K
F
-
G
-
D
---
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
V
A
G
H
D
V
----
L
K
----
E
----
P
R
-----
E
V
R
R
K
I
G
I
V
F
Q
D
Q
S
-
L
D
R
E
L
-
T
A
Y
E
N
M
---
Y
I
H
G
K
I
Y
G
Y
G
G
E
K
L
K
K
R
I
L
E
L
L
E
F
V
--
E
L
L
E
F
K
D
K
P
V
K
T
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
-
K
K
E
H
-
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
-
K
I
I
A
L
G
T
P
T
E
L
K
R
M
V
G
K
E
I
I
Y
V
R-------------------------------
D
F
I
E
-
S
-
C
R
K
L
P
D
G
R
L
E
L
N
V
E
D
---------------------
I
E
E
I
T
Y
H
K
P
T
L
N
D
V
F
L
H
L
T
G
R
E
L
R
----------------------------------------------