@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VV27: (2017-12-21 )
MKLSVGLKVANSLSLTPQLQQAIRLLQLSGLELEQEIQIQLDSNPLLEKVEDELLAESLSTLEHKETDDLTTELNADHLPDDLPVDTEWDDIYTHQSTALGTPEFEEREDNRQVHLTLKEHILEQVNLLHFSKIDQLIAYCIVDALDDKGFLDAELEEIILAVQHLLSEMDIDEEVEEDEVLVVLKHIQRLDPIGIGARNLAECLKVQLEFLPRETEYLKEARSLLQYYELLIANDLNKLLKQTGLSKEQLKFAVDLLKTLKPYPGMDFEKQESEYQIPDVVVAKKDLHWQVQLNPDVMPKLRINSFYSSMIRRADQSDDNLYLRNQMLEAKNFIKSIDERHKTLLKVATCIVEHQKAFLEIGPEAMKPLVLRDVAEEVELHESTVSRVTTNKYMLTPRGLFELKYFFSSHVGTTTGGEASSTAIRAMIKKLVSNENPRKPLSDNAIAALLKEEGIEVARRTVAKYRESLHIPSSSERKVLI
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20....-----....30---........40.......-.---50--.......-------.60..------......70........80........90........100.......---110-.........120....---...130.......140.......150.......160.......170.......180.......190.......200.......210.......220...-..-..230..-.-....240.......250-........260.......----270.......280.-------------......290.-......300.......310.......320.......330---........340......-.350--.......360-........370.......380.......390.......400......--.410.......420.......430.......440.......450..-----.-----.-----.----..460.......470...---....480-------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
K
L
S
V
G
L
K
VANSLSL
T
P
Q
L
Q
Q
A
I
R
L
-----
L
Q
LSGL---E
L
E
Q
E
I
Q
I
Q
LDSN
P
L
L
E
-
K
---
V
E
--
D
E
L
L
A
E
S
-------
L
S
T
LE------HKETDDLTTELNADHLPDDLPVDTEWDDIYTHQSTALGTPE
F
E
ERE---D---N
R
Q
V
H
L
T
L
K
E
H
I
L
E
Q
V
---
N
L
L
H
F
S
K
I
D
Q
L
I
A
Y
C
I
V
D
ALDDKGF
L
D
A
E
L
E
E
I
I
L
A
V
Q
H
L
L
S
EMDIDEEVEE
D
E
V
L
V
V
L
K
H
I
Q
RLDPIGI
G
A
R
N
L
A
E
C
L
K
V
Q
L
E
FLPR
E
T
E
Y
L
K
E
A
R
S
L
-
L
Q
-
Y
Y
E
L
L
I
A
-
N
-
D
L
N
K
L
L
K
QTGL
S
K
E
Q
L
--
K
F
A
V
D
L
L
K
TLKPYPGMDF----EKQESEYQIP
D
V
V
V
-------------AKK
D
L
H
W
Q
V
Q
-LNPDVM
P
K
L
R
I
N
S
F
Y
S
S
M
I
R
RADQSDDN
L
Y
L
R
N
Q
M
L
E
A
----
K
N
F
I
K
S
I
D
E
R
H
K
T
L
L
K
V
-
A
T
C
I
--
V
E
H
Q
K
A
F
L
E--I
G
P
E
A
M
K
P
L
V
L
R
D
V
A
E
E
V
E
L
H
E
S
T
V
S
RVTTN
K
Y
M
LTP
R
G
L
F
E
L
K
Y
F
F
--
S
SHVGTTTGGE
A
S
S
T
A
I
R
A
M
I
K
K
L
VSNENPRKPLS
D
N
A
I
A
A
L
L
K
EE-----
G
-----
I
-----
E
----
V
A
R
R
T
V
A
K
Y
R
E
SLHIPSS---SE
R
K
V
LI-------
1
PsiBlast_PDB
78.43
47%
34
- C2 -
-
5UI8
-
?
M:
[20-474]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
A
I
R
L
-----
L
Q
L
S
T
L
---
E
L
Q
Q
E
L
Q
Q
A
L
E
S
N
P
L
L
E
-
Q
---
T
D
LH
D
E
------------------------------------------------------------------------
Y
---
Q
G
E
T
T
Q
T
L
Q
D
Y
L
M
W
Q
V
---
E
L
T
P
F
T
D
T
D
R
A
I
A
T
S
I
V
D
A
V
D
D
T
G
Y
L
T
I
Q
I
E
D
I
V
D
S
I
G
--------
D
D
E
I
G
L
E
E
V
E
A
V
L
K
R
I
Q
R
F
D
P
V
G
V
A
A
K
D
L
R
D
C
L
L
I
Q
L
S
Q
F
A
K
E
T
P
W
L
E
E
A
R
L
I
-
I
S
D
H
L
D
L
L
A
N
-
H
---
R
T
L
M
R
V
T
R
L
K
E
E
V
L
--
K
E
A
V
N
L
I
Q
S
L
D
P
R
P
G
Q
S
I
----
H
T
S
E
P
E
Y
V
I
P
D
V
L
V
-------------
R
K
V
S
G
R
W
T
V
E
-
L
N
A
D
S
I
P
R
L
K
I
N
Q
Q
Y
A
A
M
-------
A
D
G
Q
F
I
R
S
N
L
Q
E
A
----
R
W
L
I
K
S
L
E
S
R
N
D
T
L
L
R
V
-
S
R
C
I
--
V
E
Q
Q
Q
A
F
F
E
--
Q
G
E
E
Y
M
K
P
M
V
L
A
D
I
A
Q
A
V
E
M
H
E
S
T
I
S
R
V
T
T
Q
K
Y
L
H
S
P
R
G
I
F
E
L
K
Y
F
F
--
S
S
----------
S
S
T
A
I
R
A
L
V
K
K
L
I
A
A
E
N
P
A
K
P
L
S
D
S
K
L
T
S
M
L
S
E
Q
-----
G
-----
I
-----
M
----
V
A
R
R
T
V
A
K
Y
R
E
S
L
S
I
P
P
S
---
N
Q
R
K
----------
19
Fugue
64.29
48%
38
- C2 -
-
5BYH
-
?
M:
[16-473]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
Q
L
Q
Q
A
I
R
L
-----
L
Q
L
S
T
L
---
E
L
Q
Q
E
L
Q
Q
A
L
E
S
N
P
L
L
E
-
Q
---
T
D
-----
L
H
D
E
-------
V
E
A
K
E
------
V
E
D
R
E
S
L
D
T
V
--------
E
L
P
L
D
A
S
W
D
E
I
Y
T
A
G
T
P
S
G
N
G
V
D
Y
Q
D
D
E
---
L
PVY
Q
G
E
T
T
Q
T
L
Q
D
Y
-
L
W
Q
V
---
E
L
T
P
F
T
D
T
D
R
A
I
A
T
S
I
V
D
A
V
D
D
T
G
Y
L
T
I
Q
I
E
D
I
V
D
S
I
G
--------
D
D
E
I
G
L
E
E
V
E
A
V
L
K
R
I
Q
R
F
D
P
V
G
V
A
A
K
D
L
R
D
C
L
L
I
Q
L
S
Q
F
A
K
E
T
P
W
L
E
E
A
R
L
I
-
I
S
-
D
H
L
D
L
L
A
-
N
H
D
F
R
T
L
M
R
V
T
R
L
K
E
E
V
L
--
K
E
A
V
N
L
I
Q
S
L
D
P
R
P
G
Q
S
I
----
Q
T
S
E
P
E
Y
V
I
P
D
V
L
V
-------------
R
K
V
S
G
R
W
T
V
E
-
L
N
A
D
S
I
P
R
L
K
I
N
Q
Q
Y
A
A
G
N
S
A
R
N
D
A
D
G
Q
-
F
I
R
S
N
L
Q
E
A
----
R
W
L
I
K
S
L
E
S
R
N
D
T
L
L
R
V
-
S
R
C
I
--
V
E
Q
Q
Q
A
F
F
E
--
Q
G
E
E
--
Y
K
P
V
L
A
D
I
A
Q
A
V
E
-
H
E
S
T
I
S
R
V
T
T
------------------------------
A
S
S
T
A
I
R
A
L
V
K
K
L
I
A
A
E
N
P
A
K
P
L
S
D
S
K
L
T
S
L
-
S
E
Q
-----
G
-----
I
----------
V
A
R
R
T
V
A
K
Y
R
E
S
L
S
I
P
P
S
---
N
Q
R
-----------
2
PsiBlast_PDB
63.16
47%
59
- C2 -
-
5BYH
-
?
M:
[16-473]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
Q
L
Q
Q
A
I
R
L
-----
L
Q
L
S
T
L
---
E
L
Q
Q
E
L
Q
Q
A
L
E
S
N
P
L
L
E
-
Q
---
T
D
LH
D
E
V
E
A
K
E
-------
V
---
E
------
D
R
E
S
L
D
T
V
----------
E
L
P
L
D
A
S
W
D
E
I
Y
T
A
G
T
P
S
G
N
G
V
D
Y
Q
D
D
E
LPV
Y
---
Q
G
E
T
T
Q
T
L
Q
D
Y
L
-
W
Q
V
---
E
L
T
P
F
T
D
T
D
R
A
I
A
T
S
I
V
D
A
V
D
D
T
G
Y
L
T
I
Q
I
E
D
I
V
D
S
I
G
--------
D
D
E
I
G
L
E
E
V
E
A
V
L
K
R
I
Q
R
F
D
P
V
G
V
A
A
K
D
L
R
D
C
L
L
I
Q
L
S
Q
F
A
K
E
T
P
W
L
E
E
A
R
L
I
-
I
S
D
H
L
D
L
L
A
N
-
H
-
D
F
R
T
L
M
R
V
T
R
L
K
E
E
V
L
--
K
E
A
V
N
L
I
Q
S
L
D
P
R
P
G
Q
S
I
----
Q
T
S
E
P
E
Y
V
I
P
D
V
L
V
-------------
R
K
V
S
G
R
W
T
V
E
-
L
N
A
D
S
I
P
R
L
K
I
N
Q
Q
Y
A
A
-
G
N
S
A
R
N
D
A
D
G
Q
F
I
R
S
N
L
Q
E
A
----
R
W
L
I
K
S
L
E
S
R
N
D
T
L
L
R
V
-
S
R
C
I
--
V
E
Q
Q
Q
A
F
F
E
--
Q
G
E
E
Y
-
K
P
-
V
L
A
D
I
A
Q
A
V
E
-
H
E
S
T
I
S
R
V
T
T
------------------------------
A
S
S
T
A
I
R
A
L
V
K
K
L
I
A
A
E
N
P
A
K
P
L
S
D
S
K
L
T
S
-
L
S
E
Q
-----
G
-----
I
----------
V
A
R
R
T
V
A
K
Y
R
E
S
L
S
I
P
P
S
---
N
Q
R
-----------
30
HHSearch
62.59
31%
-7
- C2 -
-
5UI5
-
?
V:
[17-341]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
E
E
L
Q
Q
N
I
---
K
L
E
L
-
E
G
K
E
Q
E
L
A
L
E
L
L
N
Y
L
N
E
K
G
F
L
S
K
S
V
E
E
I
S
D
V
L
-----------
R
C
S
V
E
E
L
E
K
V
R
Q
K
V
L
R
L
E
P
L
G
V
C
S
K
D
V
W
E
F
L
E
L
Q
I
E
E
I
Y
P
E
------
E
E
E
I
L
K
K
-
A
L
R
D
L
K
R
-
G
-
K
K
L
K
---------
P
E
I
--
K
---
G
K
L
S
R
L
R
L
F
P
L
S
------
A
E
K
V
Y
T
F
A
K
V
D
A
I
I
-------------
E
E
E
N
G
E
F
F
I
Y
-
L
Y
E
D
F
-
I
D
I
D
L
N
E
E
Y
W
E
L
Y
K
K
--
S
R
N
L
Q
K
E
L
K
E
A
F
E
R
Y
----
E
S
I
R
K
V
L
D
I
R
R
R
N
L
R
K
V
-
L
E
K
I
--
V
E
R
Q
K
D
F
L
T
--
G
K
-
G
S
L
K
P
L
T
L
R
E
V
S
S
E
I
G
I
H
E
S
T
L
S
R
I
V
N
S
K
Y
V
K
T
P
V
G
T
Y
S
L
R
T
F
F
--
V
R
E
S
A
E
----
G
L
T
Q
G
E
L
M
K
L
I
K
E
I
V
E
N
E
D
K
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
I
P
S
S
---
R
E
R
R
----------
3
PsiBlast_PDB
57.51
30%
-39
- C2 -
-
5UI5
-
?
I:
[33-342]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
E
L
A
L
E
L
L
N
Y
L
N
E
K
G
F
L
S
K
S
V
E
E
I
S
D
V
L
R
C
S
V
E
E
L
E
-----------
K
V
R
Q
K
V
L
R
L
E
P
L
G
V
C
S
K
D
V
W
E
F
L
E
L
Q
I
------------------
E
-
E
I
Y
P
E
E
E
-
E
-
I
L
K
K
A
L
R
D
L
K
R
G
K
K
L
K
--
P
E
I
K
G
K
L
S
R
L
R
L
F
P
---
S
----
A
E
K
V
Y
T
F
A
K
V
D
A
I
I
-------------
E
E
E
N
G
E
F
F
I
Y
-
L
Y
E
D
F
I
D
-
I
D
L
N
E
E
Y
W
E
L
Y
K
---
N
------
L
Q
K
E
L
K
E
A
FERY
E
S
I
R
K
V
L
D
I
R
R
R
N
L
R
K
V
-
L
E
K
I
--
V
E
R
Q
K
D
F
L
---
T
G
K
G
S
L
K
P
L
T
L
R
E
V
S
S
E
I
G
I
H
E
S
T
L
S
R
I
V
N
S
K
Y
V
K
T
P
V
G
T
Y
S
L
R
T
F
F
VR
E
S
A
E
G
L
T
Q
G
------
E
L
M
K
L
I
K
E
I
V
E
----
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
I
P
S
S
---
R
E
R
R
I
---------
31
HHSearch
48.19
57%
-144
- C2 -
-
2O9L
2
?
A:
[3-62]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
Q
G
E
L
M
K
L
I
K
E
I
V
E
N
E
D
K
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
I
P
S
S
---
R
E
R
R
----------
51
HHSearch
47.55
10%
-156
- C2 -
-
1PDN
2
PRD_DROME
C:
[34-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
P
C
V
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
L
N
R
Y
-
Q
E
--
T
G
S
I
R
P
G
V
----
I
G
G
S
K
----
P
R
I
A
T
P
E
I
E
N
R
I
E
E
Y
K
R
S
S
---
P
G
M
F
S
W
E
I
R
E
K
L
I
R
E
-----
G
-----
V
CDRST
A
----
P
S
V
S
A
I
S
R
L
V
-------------------------
25
Fugue
47.35
20%
15
- C3 -
-
4WZ9
3
?
A:
[40-926]
QAVDERYRLPTT
S
I
P
I
H
YD
L
H
L
R
T
EIHRNER
T
F
T
G
T
V
G
I
Q
L
Q
V
VQATD
K
L
V
M
H
N
R
GLVMS
S
A
K
V
S
S
LPNGVT
G
A
P
T
L
IG
D
V
Q
Y
S
T
D
TTFE
H
I
T
F
T
S
P
T
I
L
Q
P
G
T
Y
L
L
E
V
A
F
Q
G
R
L
A
TNDDGF
Y
V
S
S
Y
V
A
DNG
E
R
R
Y
L
A
T
T
Q
F
ESTSARMAFPCYDEPGL
K
A
T
F
T
V
S
I
T
H
S
LS
Y
K
A
I
S
NMPQK
T
T
T
D
I
ET
D
M
R
T
T
F
F
E
K
T
P
A
M
S
TYL
L
A
F
V
V
SD
F
Q
L
R
L
S
GA
Q
R
V
Y
V
RPNAFNEA
T
F
A
L
E
A
G
V
K
I
L
K
V
L
D
D
H
L
GIPYDTYMP
K
L
D
Q
I
A
I
PDFAAGAMENWG
L
V
T
Y
REQALLFNPAVST
Y
R
G
K
T
N
V
A
T
T
I
A
H
E
Y
A
H
QWFGNLVSPEWWEY
I
W
L
N
E
G
F
A
T
L
Y
E
F
Y
A
L
D
M
A
Y
PGQEYWELFNQQV
I
Q
Y
A
M
G
Q
D
G
QASTRPM
N
W
N
A
A
T
P
G
E
I
S
A
L
FDRVAY
D
K
S
G
S
V
L
N
M
M
R
H
V
L
G
D
D
N
W
K
A
G
L
K
A
Y
L
T
D
-----
R
A
L
Q
G
A
V
D
E
Q
L
Y
A
G
L
Q
S
A
I
E
G
K
G
V
L
P
-
N
GVT
V
A
--
Q
I
M
R
T
W
T
N
E
A
G
Y
P
V
L
N
V
R
R
------
S
Y
D
T
G
D
V
I
I
S
Q
E
R
F
Y
N
D
R
K
V
P
N
T
N
I
W
M
I
P
Y
N
Y
V
H
Q
A
--
K
A
D
F
N
E
F
D
---
D
---
F
Q
W
L
A
-
T
K
A
A
R
I
E
T
T
V
PAN
E
W
I
V
F
N
K
--
Q
Q
V
G
Y
Y
R
V
N
Y
-------
D
E
H
N
W
E
L
I
T
N
A
L
H
E
N
W
A
S
-----------
I
H
R
L
N
R
A
Q
L
I
D
D
A
Y
W
L
A
R
S
G
R
L
D
L
R
V
A
L
R
F
M
----
T
Y
L
R
N
E
R
E
Y
-
A
P
-
W
T
A
A
N
V
A
L
T
-
Y
F
N
N
R
L
R
G
T
A
E
Y
H
N
F
L
--
I
F
V
D
A
L
I
E
D
I
Y
S
L
L
T
I
D
A
VSPD
D
T
L
L
H
K
Y
L
V
Q
T
I
S
T
W
A
C
S
M
GY
T
D
C
L
M
K
T
A
A
L
L
K
A
E
A
S
G
T
G
P
A
V
H
P
D
I
A
S
V
T
Y
C
Y
G
M
--
R
S
A
L
E
S
E
F
Q
Y
L
Y
R
K
M
M
N
S
----
K
N
-----
L
A
E
R
T
M
L
I
D
S
-
L
G
C
S
NN
K
E
F
L
K
A
F
L
T
T
A
L
G
S
I
N
Y
R
A
D
E
R
R
R
V
V
Q
A
I
Y
S
G
G
R
T
G
V
D
A
L
I
-
E
F
L
M
D
P
A
L
V
N
E
F
V
S
T
L
--
S
------------
T
S
T
L
N
S
A
L
S
A
I
A
S
R
T
N
--
N
V
E
E
M
N
K
L
N
A
L
I
T
A
L
-----
G
-----
S
-----
R
----
V
N
S
Q
T
A
A
N
L
R
T
T
A
Q
A
N
L
D
W
V
N
G
F
E
G
L
M
L
S
N
F
L
AEA
20
Fugue
45.95
46%
-139
- C2 -
-
2AHQ
-
?
A:
[1-67]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
S
L
R
T
F
F
--
V
R
----
E
S
A
E
G
L
T
Q
G
E
L
M
K
L
I
K
E
I
V
E
N
E
D
K
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
---------------------
4
PsiBlast_PDB
45.26
68%
-71
- C2 -
-
2MT3
-
RP54_ECOLI
A:
[414-477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
S
S
T
A
I
R
A
L
V
K
K
L
I
A
A
E
N
P
A
K
P
L
S
D
S
K
L
T
S
L
L
S
E
Q
-----
G
-----
I
-----
M
----
V
A
R
R
T
V
A
K
Y
R
E
S
L
S
I
P
P
S
---
N
Q
R
K
Q
L
V
-------
39
HHSearch
45.07
14%
-111
- C2 -
-
6PAX
-
PAX6_HUMAN
A:
[34-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
P
C
D
I
S
R
I
L
Q
V
S
N
G
C
V
S
K
I
L
G
-
R
Y
Y
A
T
--
G
S
I
R
P
R
------
A
I
G
G
S
--
K
P
R
V
A
T
P
E
V
V
S
K
I
A
Q
Y
K
Q
E
---
C
P
S
I
F
A
W
E
I
R
D
R
L
L
S
E
-----
G
VCTND
N
-----
I
----
P
S
V
S
S
I
N
R
V
L
R
N
L
A
S
--------------------
21
Fugue
44.58
22%
-135
- C2 -
-
2K9M
-
?
A:
[69-198]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
P
S
E
L
E
E
L
Q
Q
N
I
---
K
L
E
-
L
E
G
K
E
Q
E
L
A
L
E
L
L
N
Y
L
N
E
K
G
F
L
S
K
S
V
E
E
I
S
D
V
L
-----------
R
C
S
V
E
E
L
E
K
V
R
Q
K
V
L
R
L
E
P
L
G
V
C
S
K
D
V
W
E
F
L
E
L
Q
I
E
E
I
Y
P
E
E
-----
E
E
I
L
-
K
K
-
A
L
R
D
L
K
R
-
G
-
K
K
L
K
P
E
I
K
G
K
L
S
R
L
R
L
--
F
P
L
S
S
S
A
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
44.54
69%
-73
- C2 -
-
2MT3
-
RP54_ECOLI
A:
[415-476]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
S
T
A
I
R
A
L
V
K
K
L
I
A
A
E
N
P
A
K
P
L
S
D
S
K
L
T
S
L
L
S
E
Q
-----
G
-----
I
-----
M
----
V
A
R
R
T
V
A
K
Y
R
E
S
L
S
I
P
P
S
---
N
Q
R
K
Q
L
--------
7
PsiBlast_PDB
44.42
64%
-123
- C2 -
-
2O9L
2
?
A:
[11-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
K
E
I
V
E
N
E
D
K
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
I
P
S
S
---
R
E
R
R
I
---------
6
PsiBlast_PDB
44.19
64%
-96
- C2 -
-
2O8K
2
?
A:
[11-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
K
E
I
V
E
N
E
D
K
R
K
P
Y
S
D
Q
E
I
A
N
I
L
K
E
K
-----
G
-----
F
-----
K
----
V
A
R
R
T
V
A
K
Y
R
E
M
L
G
I
P
S
S
---
R
E
R
R
I
---------
42
HHSearch
42.80
16%
-195
- C2 -
-
2LNB
-
ZBP1_HUMAN
A:
[33-57]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
V
K
L
A
Q
L
V
K
E
C
Q
A
P
K
R
E
L
N
Q
V
L
Y
R
-------------------------------------------------------------------------------------------------------------------------
38
HHSearch
42.59
10%
-103
- C- -
-
1K78
-
PAX5_HUMAN
A:
[49-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
P
C
D
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
L
G
R
-
Y
Y
E
--
T
G
S
I
K
P
G
V
-----
I
G
G
S
---
K
P
K
V
A
T
P
K
V
V
E
K
I
A
E
Y
K
R
Q
---
N
P
T
M
F
A
W
E
I
R
D
R
L
L
A
E
RVCDN
D
-----
T
-----
V
----
P
S
V
S
S
I
N
R
I
I
R
T
K
----------------------
35
HHSearch
40.41
33%
-181
- C2 -
-
1RZR
2
CCPA_BACME
C:
[1-27]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
-----------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
40.06
25%
-156
- C2 -
-
2K9M
-
?
A:
[89-151]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
E
L
A
L
E
L
L
N
Y
L
N
E
K
G
F
L
S
K
S
V
E
E
I
S
D
V
L
R
C
S
V
E
E
L
E
-----------
K
V
R
Q
K
V
L
R
L
E
P
L
G
V
C
S
K
D
V
W
E
F
L
E
L
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
39.89
15%
33
* C3 *
-
4D2I
1
HERA_SULSO
A:
[1-476]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
I
G
Y
V
I
G
Q
A
T
T
Q
E
A
L
I
L
A
E
R
P
V
R
L
G
T
Y
V
V
L
E
Y
D
N
V
---
K
A
L
G
L
I
T
N
V
T
R
G
S
P
L
L
D
D
N
---
M
N
--
D
I
E
I
V
Q
R
-------
L
K
Q
F
N
NS
I
P
V
Y
T
K
A
K
V
K
L
L
C
D
M
N
N
H
F
L
M
P
D
I
P
P
---
F
A
G
T
P
A
R
E
A
E
D
E
E
L
K
S
I
Y
S
Q
D
---
G
---
Q
I
R
I
G
S
L
I
G
K
N
V
E
V
K
L
---
N
I
N
S
F
A
R
--
H
L
A
I
L
A
A
T
G
S
--
G
K
S
N
T
V
A
V
L
S
Q
R
I
S
E
L
G
G
S
V
L
I
F
D
Y
H
G
E
Y
Y
D
S
D
I
K
N
L
N
R
I
E
P
K
L
N
P
L
Y
M
T
P
R
E
F
S
T
L
L
E
I
R
--------
E
N
A
I
I
Q
Y
R
I
-
L
R
-
R
A
F
I
K
V
T
-
N
-
G
I
R
A
A
L
A
A
G
Q
I
P
F
S
T
L
N
S
Q
F
Y
E
L
M
A
D
A
L
K
D
E
V
L
N
K
F
----
E
E
F
M
D
R
Y
--
S
N
V
I
-----------------
D
L
T
------
S
S
D
I
I
E
K
V
K
R
G
K
V
N
V
V
S
L
T
Q
L
D
E
D
S
M
D
A
V
V
S
H
Y
L
R
R
I
----
L
D
S
R
K
D
F
K
R
S
K
N
S
G
L
K
F
P
I
I
A
V
--
I
E
E
A
H
V
F
L
S
--
K
N
E
N
T
L
T
K
Y
W
A
S
R
I
A
R
E
G
R
K
F
G
V
G
L
T
I
V
S
Q
R
P
K
G
L
D
E
N
I
L
S
Q
M
T
N
K
I
--
I
L
K
I
-------
I
E
P
T
D
K
K
Y
I
L
E
---
S
S
D
N
L
S
E
D
L
A
E
-
Q
L
S
S
L
D
V
G
E
-----
A
-----
I
-----
I
I
G
KI
V
K
L
P
A
V
V
K
I
D
M
F
E
G
K
L
L
G
---
S
D
P
D
M
I
G
-------