@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TY77: (2017-12-14 )
MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKDNITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLGVTANSVNVFVQGVRVLPD
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.......-.20........30.------.-......40...--.....50---.....---------------...60....----....70........80.-------..-.....----90........-100........110.......120--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
A
V
K
I
QTSA
G
T
I
E
I
T
N
D
V
-
I
A
T
V
VGG
A
A
T
D
V
F
G
------V-VGMA
S
K
N
Q
I
K
D
--
N
I
T
E
I
L
R
---KENYS---------------R
G
V
V
V
R
QED----N
G
I
A
V
D
V
Y
T
I
I
SYGT
K
I
-------
S
E
-
V
S
R
N
V
----
Q
E
K
V
K
Y
N
L
E
A
-
L
L
-
G
VTAN
S
V
N
V
F
V
Q
G
V
RVLPD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
66.48
13%
-
- C1 -
-
3V6G
-
?
A:
[14-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G
R
R
Q
A
I
V
E
A
A
E
R
V
I
A
R
Q
G
L
G
G
L
S
H
R
R
-
V
A
A
E
A
N
V
P
V
G
S
T
T
Y
Y
FND
L
D
A
-
L
R
E
A
A
L
A
H
A
A
N
--
A
S
A
D
L
L
A
---
Q
W
R
S
D
L
DKDRD
L
A
A
T
L
A
R
L
T
T
V
Y
L
A
D
Q
D
R
----
Y
R
T
L
N
E
L
Y
M
A
A
A
H
R
P
E
L
-------
Q
R
-
L
A
R
L
W
----
P
D
G
L
L
A
L
L
E
P
-
R
I
G
R
R
A
A
N
A
V
T
V
F
F
D
G
A
T
L
H
A
L
I
T
GTPLS
T
D
E
L
T
D
A
I
A
R
L
V
ADG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
63.75
23%
-76
- C1 -
-
5HO5
-
?
B:
[27-80]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
G
R
N
V
G
----
E
D
V
H
L
D
I
N
I
Y
V
D
A
D
L
K
V
-------
F
E
--
S
D
L
V
----
A
D
A
I
R
R
K
I
E
A
-
E
V
D
H
V
--
R
D
V
H
V
G
V
T
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
61.96
19%
-167
- C1 -
-
3W61
-
?
A:
[11-79]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
E
A
A
E
R
V
P
G
------
V
-
R
G
V
I
H
----------------------------------------
L
R
A
R
Y
V
G
----
Q
D
I
W
A
D
M
I
I
G
V
D
P
E
N
T
V
-------
E
Q
--
A
H
E
I
----
C
E
A
V
Q
A
A
V
C
G
-
K
I
R
R
I
--
E
S
L
A
V
S
A
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
58.97
13%
-40
- C1 -
-
5UFL
-
CIP2A_HUMAN
A:
[5-561]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
A
C
L
K
S
L
L
L
T
V
S
Q
YKA
N
A
T
Q
L
L
R
H
L
E
V
I
S
R
L
F
T
S
N
Q
I
L
T
S
E
C
L
S
C
L
-
V
E
L
L
E
D
P
S
A
S
L
I
L
S
------
I
-
I
G
L
L
S
Q
L
A
V
D
I
--
E
T
R
D
C
L
Q
N
TL
N
S
V
L
A
---------------
G
V
V
C
R
T
D
S
V
----
F
L
Q
C
I
Q
L
L
Q
K
L
T
Y
N
V
K
I
FYSGAN
I
D
E
-
L
I
T
F
L
----
I
D
H
I
Q
S
E
L
K
M
P
C
L
-
G
L
L
A
N
L
C
R
H
N
L
S
V
Q
T
H
I
K
T
LSNS
F
Y
R
T
L
I
T
L
L
A
HSS
L
T
V
V
V
F
A
L
S
I
L
S
S
L
TLNEEVGEKLFHARN
I
H
Q
T
F
Q
L
I
F
N
I
L
I
NGDGT
L
T
R
K
Y
S
V
D
L
L
M
D
L
L
K
N
P
K
I
A
D
Y
L
T
R
YEH
F
S
S
C
L
H
Q
V
L
G
L
L
N
GKD
P
D
S
S
S
K
V
L
E
L
L
L
A
F
C
S
V
T
Q
L
R
H
M
L
T
Q
M
M
F
ES
H
T
K
C
L
E
P
T
V
A
L
L
R
W
L
S
QPLDGN
C
S
V
L
A
L
E
L
F
K
E
I
F
E
D
V
I
D
A
ANCSSA
D
R
F
V
T
L
L
L
P
T
I
L
D
Q
LQFTEQNLD
E
A
L
T
R
K
K
C
E
R
I
A
K
A
I
E
V
L
L
T
L
C
GD
D
T
L
K
M
H
I
A
K
I
LT
T
V
K
C
T
T
L
I
E
Q
Q
F
T
Y
G
KIDLGFGTKVADS
E
L
C
K
L
A
A
D
V
I
L
K
T
L
D
L
I
N
K
L
KPLVPG
M
E
V
S
F
Y
K
I
L
Q
DPRL
I
T
P
L
A
F
A
L
T
SDN
R
E
Q
V
Q
S
G
L
R
I
L
L
E
A
APLPDFP
A
L
V
L
G
E
S
I
A
A
N
N
A
Y
R
Q
Q
E
38
HHSearch
57.83
29%
-178
- C1 -
-
4FAZ
-
?
B:
[13-46]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
-
Q
K
R
A
V
----
I
E
K
V
T
Q
A
M
M
E
-
A
V
-
G
A
P
K
E
N
V
R
V
W
I
H
D
V
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
57.55
17%
-107
- C1 -
-
2X5C
-
?
A:
[30-128]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
K
Q
E
Y
D
M
A
A
D
L
V
R
M
L
R
G
L
------
G
V
F
M
H
A
K
C
P
------
R
-
C
G
A
E
G
S
V
S
I
V
E
--
T
----------
K
N
G
Y
---------------
K
Y
L
V
I
R
H
P
D
----
G
G
T
H
T
V
P
K
T
D
I
---
S
A
I
-------
L
K
-
E
L
C
E
V
----
K
K
D
L
E
Y
V
L
K
R
-
Y
K
-
E
Y
E
E
E
G
------
G
V
K
F
C
A
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
56.95
21%
-92
- C1 -
-
5HOK
-
?
C:
[27-79]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
G
R
N
V
G
----
E
D
V
H
L
A
I
N
I
Y
V
D
A
D
L
K
V
-------
F
E
--
S
D
L
V
----
A
D
A
I
R
R
K
I
E
A
-
E
V
D
H
V
--
R
D
V
H
V
G
V
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
54.99
9%
-163
- C1 -
-
3BYR
-
?
A:
[33-85]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
T
R
R
A
G
----
P
R
S
F
L
E
F
H
L
V
V
R
G
D
T
P
V
-------
E
E
--
A
H
R
L
----
C
D
E
L
E
R
A
L
A
Q
-
A
F
-
P
G
-
L
-
Q
A
T
I
H
V
E
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
54.02
13%
-125
- C1 -
-
3J1Z
-
?
Q:
[532-585]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
T
R
Q
A
G
----
K
T
V
F
I
Q
F
H
L
E
L
D
G
N
L
S
L
-------
N
E
--
A
H
S
I
----
T
D
T
T
G
L
R
V
K
A
-
A
F
-
E
D
-
A
-
E
V
I
I
H
Q
D
P
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
51.60
45%
-222
- C2 -
-
1WNE
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
51.38
9%
-162
- C1 -
-
3BYP
-
?
A:
[33-85]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
T
R
R
A
G
----
P
R
S
F
L
E
F
H
L
V
V
R
G
D
T
P
V
-------
E
E
--
A
H
R
L
----
C
D
E
L
E
R
A
L
A
Q
-
A
F
-
P
G
-
L
-
Q
A
T
I
H
V
E
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
51.12
17%
76
- C1 -
-
5B86
-
TNAP2_MOUSE
A:
[17-600]
DGPLPT
V
E
E
L
K
E
A
L
E
H
GRLEV
A
W
Q
V
L
A
L
E
R
Q
L
E
A
A
A
A
A
GGMS
N
E
E
L
V
W
R
Q
S
K
V
E
A
L
Y
V
L
L
C
D
Q
V
L
G
V
L
R
R
PLEAAP
E
R
L
S
Q
A
L
A
V
V
S
Q
E
E
L
E
D
R
RASGGPLAAALEATRPRR
W
L
Q
R
W
R
G
V
V
A
E
V
A
A
E
R
L
D
AQPGRS
E
A
E
S
R
F
L
H
M
G
R
T
M
K
E
D
L
E
V
V
V
E
R
L
K
P
L
F
PDEFN
V
V
R
T
Y
A
E
S
Y
H
Y
H
F
A
S
H
L
C
A
L
A
Q
FELC
E
R
D
T
Y
L
L
L
L
W
V
Q
NL
Y
P
N
D
I
L
N
S
P
K
L
A
Q
E
L
Q
G
V
G
L
G
S
L
L
P
P
K
Q
I
R
L
L
E
------
A
M
F
L
S
N
E
V
T
S
V
K
Q
L
M
A
R
A
L
E
L
E
---
S
Q
R
W
T
---------------
Q
D
V
A
P
Q
S
L
D
GHCH
S
E
L
A
I
D
I
L
Q
I
I
S
Q
G
Q
T
K
-------
A
E
N
I
T
S
D
V
G
M
Q
I
K
Q
L
L
L
V
E
L
A
A
-
L
L
-
R
S
Y
Q
R
A
F
D
E
F
L
E
K
S
K
L
L
R
N
Y
R
V
N
I
M
A
N
I
N
N
C
L
F
F
W
T
S
V
E
Q
K
WQIS
H
D
S
L
N
R
L
L
E
P
L
K
D
L
K
A
H
G
F
D
T
L
L
Q
S
L
F
L
D
L
K
P
L
F
K
K
F
T
Q
T
R
WAN
P
V
E
T
L
E
E
I
I
T
T
V
S
S
S
LPEFSELQ
D
C
F
R
E
E
L
M
E
T
V
H
L
H
L
V
K
E
Y
I
I
R
L
C
KRRLVLKT
A
E
Q
Q
Q
Q
L
A
R
H
I
L
A
N
A
D
A
I
Q
G
F
C
T
E
N
GSTATWLHR
A
L
P
M
I
A
E
I
I
R
LQD
S
S
A
I
K
I
E
V
A
T
Y
A
T
W
YPDFS
K
G
H
L
N
A
I
L
A
IKGNLPS
S
E
V
R
S
I
R
N
I
L
DINTGV
Q
E
P
P
RPLFSLIKVT-------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
50.90
45%
-245
- C2 -
-
1U09
-
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.66
45%
-215
- C2 -
-
3KLV
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.44
45%
-231
- C2 -
-
2EC0
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
50.40
29%
-140
- C1 -
-
2OPA
-
4OT_BACSU
B:
[13-46]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
-
Q
K
R
N
L
----
V
E
K
V
T
E
A
V
K
E
-
T
T
-
G
A
S
E
E
K
I
V
V
F
I
E
E
M
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
50.31
45%
-172
- C2 -
-
3NL0
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
49.76
45%
-219
- C2 -
-
3KOA
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
49.32
29%
-149
- C1 -
-
2OP8
-
4OT_BACSU
A:
[13-46]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
-
Q
K
R
N
L
----
V
E
K
V
T
E
A
V
K
E
-
T
T
-
G
A
S
E
E
K
I
V
V
F
I
E
E
M
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.90
45%
-219
- C2 -
-
3KMS
2
?
A:
[319-340]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
R
H
Y
----
E
G
V
E
L
D
T
Y
T
M
I
S
Y
G
D
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------