@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYD8: (2017-12-14 )
MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGKSTFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENCMSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPDVLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVIAEEGTPEDIFVHPKEERTKEFLSRILNA
Atome Classification :
(34 SA)
.........10........---20........30........40........50........60........-----------70-----------------........80........90........100------.......110........120....----------...130.....-..140.......150.....-..160.......170.......180......-..190.......200.......210...-....220.......230--.......240....-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNE
K
I
I
E
I
K
H
L
R
K
SFGE
N
E
---
V
L
K
D
I
S
V
T
VNKG
E
V
V
T
I
IGSSGS
G
K
S
T
F
L
R
C
I
N
L
LEKPTG
G
E
I
I
YNG
E
N
V
-----------LA-----------------PKYNL
P
K
Y
R
T
N
L
G
M
V
F
Q
S
F
N
LFN
N
M
N
V
L
E
N
C
------MSGQ
T
T
V
LK-R
D
K
E
T
A
K
K
V
A
I
E
N
L
E
----------
K
VGMDRYIEAK-PAQLSGGQ
K
Q
R
V
A
I
A
R
ALSM-NP
D
V
L
L
FDEPTSAL
D
P
E
M
V
G
E
V
L
-
N
T
I
K
D
L
A
-HT
G
L
T
M
L
I
V
TH
E
M
E
F
A
K
DVSD
R
V
I
F
M
DK-GVIAEEGTPE
D
I
F
VHP
K
--
E
E
R
T
K
E
F
L
S
R
I
LNA-
4
PsiBlast_PDB
96.30
58%
-120
- C1 -
-
4YMV
1
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
6
PsiBlast_PDB
95.49
58%
-122
- C1 -
-
2OLJ
3
?
A:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
30
PsiBlast_CBE
94.77
58%
-111
- C1 -
-
2OLK
2
?
B:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
28
PsiBlast_CBE
94.41
58%
-114
- C1 -
-
2OLK
1
?
D:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
29
PsiBlast_CBE
94.35
58%
-117
- C1 -
-
2OLK
1
?
C:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
8
PsiBlast_PDB
94.30
58%
-117
- C1 -
-
2OUK
-
?
A:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
7
PsiBlast_PDB
93.88
58%
-118
- C1 -
-
2OLK
1
?
A:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
1
PsiBlast_PDB
93.84
58%
-120
- C1 -
-
4YMS
-
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
9
PsiBlast_PDB
93.82
58%
-114
- C1 -
-
2Q0H
3
?
A:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
11
PsiBlast_PDB
93.78
58%
-108
- C1 -
-
3C41
2
?
J:
[2-242]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
21
PsiBlast_CBE
93.63
58%
-120
- C1 -
-
4YMV
1
?
A:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
32
PsiBlast_CBE
93.50
58%
-116
- C1 -
-
3C41
2
?
K:
[2-242]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
5
PsiBlast_PDB
93.41
58%
-118
- C1 -
-
4YMW
-
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
23
PsiBlast_CBE
93.06
58%
-117
- C1 -
-
3C4J
2
?
B:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
12
PsiBlast_PDB
92.64
55%
-106
- C1 -
-
4U00
1
?
A:
[3-243]
---
P
I
I
R
I
R
N
L
H
K
W
F
G
P
L
H
---
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-----------
K
D
-----------------
D
R
-
A
L
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
------
T
L
A
P
M
R
V
R
R
-
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
----------
R
V
G
I
L
D
Q
A
R
K
Y
-
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
D
V
M
R
D
L
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
-
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
R
P
K
--
E
E
R
T
R
S
F
L
Q
R
V
L
H
--
22
PsiBlast_CBE
92.57
58%
-124
- C1 -
-
4YMU
1
?
A:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
10
PsiBlast_PDB
92.56
58%
-112
- C1 -
-
3C4J
2
?
A:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
2
PsiBlast_PDB
91.87
58%
-120
- C1 -
-
4YMT
-
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
24
PsiBlast_CBE
91.10
58%
-119
- C1 -
-
2Q0H
3
?
B:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
3
PsiBlast_PDB
91.09
58%
-119
- C1 -
-
4YMU
1
?
J:
[1-240]
----
M
I
F
V
N
D
V
Y
K
N
F
G
S
L
E
---
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-----------
N
N
-----------------
G
K
V
N
I
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
L
A
P
V
K
V
K
K
-
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
----------
K
V
G
L
L
D
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
-
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
-
N
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
-
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
--
N
E
R
T
R
E
F
L
S
K
I
L
---
31
PsiBlast_CBE
90.62
58%
-114
- C1 -
-
2OLJ
2
?
B:
[23-263]
---
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
E
---
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
-----------
K
A
-----------------
K
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
----------
K
V
G
L
K
D
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
-
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
-
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
-
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
--
H
E
R
T
K
A
F
L
S
K
V
F
---
14
PsiBlast_PDB
79.12
53%
-9
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-253]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
H
E
---
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KDGQLK
V
A
-----------------
D
K
N
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
------
M
E
A
P
I
Q
V
L
G
-
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
----------
K
V
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
-
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
-
R
I
M
Q
Q
L
A
-
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
-
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
--
S
P
R
L
Q
Q
F
L
-------
127
Fugue
67.72
52%
10
- C1 -
-
1B0U
1
HISP_SALTY
A:
[5-261]
---
N
K
L
H
V
I
D
L
H
K
R
Y
G
G
--HEV
L
K
-
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
---------------
Q
NI
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
L
R
T
-
R
-
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
------
M
E
A
P
I
Q
V
L
-G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
GIDERAQG---------
K
Y
-
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E-
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
-
R
I
M
Q
Q
L
A
-
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
-Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
-QS
P
R
L
Q
Q
F
L
K
G
S
L
K
K
L
E
86
PsiBlast_CBE
67.65
35%
-106
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[5-232]
-----
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
-----------
F
S
-----------------
K
N
T
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
------
A
Y
G
L
G
N
G
K
G
-
R
T
A
Q
E
R
Q
R
I
E
-
A
M
L
E
----------
L
T
G
I
S
E
L
A
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
--
D
--------------
87
PsiBlast_CBE
65.83
35%
-107
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[5-237]
-----
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
-----------
F
S
-----------------
K
N
T
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
------
A
Y
G
L
G
N
G
K
G
-
R
T
A
Q
E
R
Q
R
I
E
-
A
M
L
E
----------
L
T
G
I
S
E
L
A
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
-
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
--
D
--------------
132
HHSearch
65.14
33%
-101
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-236]
--
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
T
P
---
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
-----------
F
S
-----------------
K
N
T
N
L
P
V
R
E
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
------
A
Y
G
L
G
N
G
K
G
--
R
T
A
Q
E
R
Q
R
I
E
A
M
L
E
----------
L
T
G
I
S
E
L
A
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
-
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
-
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
-
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
P
A
--
D
L
D
A
A
----------
111
PsiBlast_CBE
38.72
32%
-25
- C1 -
-
2FGJ
2
D:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
SLANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
98
PsiBlast_CBE
37.33
33%
-32
- C1 -
-
2FF7
1
A:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
LANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
101
PsiBlast_CBE
36.90
32%
-21
- C1 -
-
2FGK
2
D:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
SLANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
104
PsiBlast_CBE
36.20
32%
-29
- C1 -
-
2FGK
2
HLYBP_ECOLX
A:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
LANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
119
PsiBlast_CBE
35.85
32%
-28
- C1 -
-
1XEF
2
HLYBP_ECOLX
A:
[18-229]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
L
ANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
115
PsiBlast_CBE
35.49
32%
-27
- C1 -
-
2FFA
2
A:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
S
LANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
A
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
103
PsiBlast_CBE
35.42
32%
-21
- C1 -
-
2FGK
2
HLYBP_ECOLX
B:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
SLANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------
102
PsiBlast_CBE
35.00
32%
-28
- C1 -
-
2FGK
2
HLYBP_ECOLX
C:
[24-235]
----------------------
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
-----------
A
L
-----------------
A
D
P
N
W
--
L
R
R
Q
V
G
V
V
L
Q
D
-
N
V
L
L
N
R
S
I
I
D
N
I
SLANPG
M
S
V
E
K
V
I
Y
A
-
A
K
L
A
G
A
H
D
F
I
S
E
L
R
E
------------
G
Y
N
T
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
-
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
-
R
N
M
H
K
I
C
--
K
G
R
T
V
I
I
I
A
H
R
L
S
T
V
K
N
-
A
D
R
I
I
V
M
E
K
-
G
K
I
V
E
Q
G
K
H
K
E
L
L
S
E
P
E
-----------------