@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYI5: (2017-12-14 )
MSDDMLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHFHEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKRAKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLEDPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVDKIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADSGWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFFSFGDAMFVK
Atome Classification :
(20 SA)
--------------------------------------------.........10........20........30....----------....40-........50.......--.60........70---------------........80.......-.90....-----....100.......110-------.......-------120.......130.......140.......150------------.......160.......170--------.........180.......190------------------.........200.......210.......220.......230..-----------.....240.......250....--...260.......270--....-....280.......290.......-300.......310.......320.------------......330.......340---.....---------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------------------------------------------MSDDMLTTEDFDFDL
P
E
E
L
I
A
QTPLKDRDH
S
R
L
L
V
----------
L
DRKTG-EM
E
D
K
H
F
H
E
I
I
E
ELQPG--
D
A
L
V
MNN
T
R
V
L
P
A
---------------
R
LYGEKPDTGA
H
L
E
V
L
L
-
L
TNTQG
D
-----
T
W
E
T
L
IK
P
A
K
RAKVG
T
R
-------
I
SFGD
G
R
-------
L
Q
A
V
V
K
E
E
L
E
HGG
R
I
I
D
F
EYE
G
I
F
L
E
I
L
E
S
LGE------------MPL
P
P
Y
I
K
E
RLEDPDR
Y
Q
----------
T
V
Y
A
KENGSAAAPT
A
G
L
H
F
T
--------------------
K
E
L
L
D
E
I
E
AKG
V
E
L
V
Y
L
T
L
H
VGLGTFRPV
S
V
D
K
I
E
E
H
H
M
H
S
E
F
Y
-----------
R
L
T
E
E
A
A
E
R
L
N
Q
V
R
KNG
G
K
I
V
A
--
V
GTT
S
I
R
T
L
E
T
IGTK---FN
G
E
-
I
KADSG
W
T
D
I
F
ITPGY
E
F
K
V
V
E
A
F-STNFHL
P
K
S
T
L
V
M
L
V
S
A
FAG
R
E
L
T
------------
L
S
A
Y
Q
H
A
I
E
E
R
Y
R
FFSFG
D
---
A
M
FVK---------------------
1
PsiBlast_PDB
87.46
66%
-110
- C5 -
-
1YY3
-
QUEA_BACSU
A:
[6-341]
------------------------------------------------------
F
D
F
E
L
P
E
R
L
I
A
Q
V
P
L
E
Q
R
D
A
S
R
L
M
V
----------
L
D
K
H
T
G
-
E
L
T
D
S
S
F
K
H
I
I
S
F
F
N
E
G
--
D
C
L
V
L
N
N
T
R
V
L
P
A
---------------
R
L
F
G
T
K
E
D
T
G
A
K
V
E
L
L
L
-
L
K
Q
E
T
G
D
-----
K
W
E
T
L
A
K
P
A
K
R
V
K
K
G
T
V
-------
V
T
F
G
D
G
R
-------
L
K
A
I
C
T
E
E
L
E
H
G
G
R
K
M
E
F
Q
Y
D
G
I
F
Y
E
V
L
E
S
L
G
E
------------
M
P
L
P
P
Y
I
K
E
Q
L
D
D
K
E
----------------------
A
A
A
P
T
A
G
L
H
F
T
--------------------
E
E
I
L
Q
Q
L
K
D
K
G
V
Q
I
E
F
I
T
L
H
V
G
L
G
T
F
R
-----------
M
H
A
E
F
Y
-----------
Q
M
S
E
E
T
A
A
A
L
N
K
V
R
E
N
G
G
R
I
I
S
--
V
G
T
T
S
T
R
T
L
E
T
I
A
G
E
---
H
D
G
Q
-
F
K
A
S
S
G
W
T
S
I
F
I
Y
P
G
Y
E
F
K
A
I
D
G
M
-
I
T
N
F
H
L
P
K
S
S
L
I
M
L
V
S
A
L
A
G
R
E
N
I
------------
L
R
A
Y
N
H
A
V
E
E
E
Y
R
F
F
S
F
G
D
---
A
M
L
I
----------------------
31
HHSearch
84.93
65%
-84
- C5 -
-
1YY3
-
QUEA_BACSU
A:
[4-341]
----------------------------------------------------
D
L
F
D
F
E
L
P
E
R
L
I
A
Q
V
P
L
E
Q
R
D
A
S
R
L
M
V
----------
L
D
K
H
T
G
-
E
L
T
D
S
S
F
K
H
I
I
S
F
F
N
E
G
--
D
C
L
V
L
N
N
T
R
V
L
P
A
---------------
R
L
F
G
T
K
E
D
T
G
A
K
V
E
L
L
L
-
L
K
Q
E
T
G
D
-----
K
W
E
T
L
A
K
P
A
K
R
V
K
K
G
T
V
-------
V
T
F
G
D
G
R
-------
L
K
A
I
C
T
E
E
L
E
H
G
G
R
K
M
E
F
Q
Y
D
G
I
F
Y
E
V
L
E
S
L
G
E
------------
M
P
L
P
P
Y
I
K
E
Q
L
D
D
K
E
----------------------
A
A
A
P
T
A
G
L
H
F
T
--------------------
E
E
I
L
Q
Q
L
K
D
K
G
V
Q
I
E
F
I
T
L
H
V
G
L
G
T
F
R
-----------
M
H
A
E
F
Y
-----------
Q
M
S
E
E
T
A
A
A
L
N
K
V
R
E
N
G
G
R
I
I
S
--
V
G
T
T
S
T
R
T
L
E
T
I
A
G
----
E
H
D
G
Q
F
K
A
S
S
G
W
T
S
I
F
I
Y
P
G
Y
E
F
K
A
I
D
G
M
-
I
T
N
F
H
L
P
K
S
S
L
I
M
L
V
S
A
L
A
G
R
E
N
I
------------
L
R
A
Y
N
H
A
V
E
E
E
Y
R
F
F
S
F
G
D
---
A
M
L
I
----------------------
19
PsiBlast_CBE
81.48
51%
-137
- C5 -
-
1VKY
1
QUEA_THEMA
B:
[16-346]
----------------------------------------------------
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
----------
L
H
R
K
T
Q
-
R
I
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
--
D
L
L
V
L
N
V
S
K
V
I
P
A
---------------
R
L
Y
A
R
K
---
G
A
S
I
E
I
L
L
-
I
E
R
L
E
E
G
-----
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
-------
L
V
I
-
D
E
D
-------
L
S
A
V
C
L
G
R
G
E
D
G
T
R
I
L
K
F
Q
P
Q
D
D
R
L
-
I
F
E
K
-
G
------------------------------------------------------
T
A
G
L
H
F
T
--------------------
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
G
I
----------------
H
E
E
F
Y
-----------
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
--
V
G
T
T
T
V
R
T
L
E
T
I
A
R
-----
L
P
E
-
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
-
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
------------
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
---
A
M
L
I
----------------------
2
PsiBlast_PDB
81.29
51%
-142
- C5 -
-
1VKY
1
QUEA_THEMA
A:
[16-346]
----------------------------------------------------
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
----------
L
H
R
K
T
Q
-
R
I
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
--
D
L
L
V
L
N
V
S
K
V
I
P
A
---------------
R
L
Y
A
R
K
----
A
S
I
E
I
L
L
-
I
E
R
L
E
E
G
-----
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
-------
L
V
I
-
D
E
D
-------
L
S
A
V
C
L
G
R
G
E
D
G
T
R
I
L
K
F
Q
P
Q
D
D
R
L
-
I
F
E
K
-
G
------------------------------------------------------
T
A
G
L
H
F
T
--------------------
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
-----------
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
--
V
G
T
T
T
V
R
T
L
E
T
I
A
R
-----
L
P
E
-
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
-
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
------------
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
---
A
M
L
I
----------------------
32
HHSearch
81.02
51%
-137
- C5 -
-
1VKY
1
QUEA_THEMA
B:
[16-347]
----------------------------------------------------
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
----------
L
H
R
K
T
Q
-
R
I
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
--
D
L
L
V
L
N
V
S
K
V
I
P
A
---------------
R
L
Y
A
R
K
---
G
A
S
I
E
I
L
L
-
I
E
R
L
E
E
G
-----
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
-------
L
V
I
D
E
D
--------
L
S
A
V
C
L
G
R
G
E
D
G
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------------------------
T
A
G
L
H
F
T
--------------------
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
G
I
----------------
H
E
E
F
Y
-----------
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
--
V
G
T
T
T
V
R
T
L
E
T
I
A
R
----
L
P
E
--
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
-
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
------------
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
---
A
M
L
I
L
---------------------
33
HHSearch
80.21
51%
-142
* C5 *
-
1VKY
1
QUEA_THEMA
A:
[16-347]
----------------------------------------------------
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
----------
L
H
R
K
T
Q
-
R
I
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
--
D
L
L
V
L
N
V
S
K
V
I
P
A
---------------
R
L
Y
A
R
K
----
A
S
I
E
I
L
L
-
I
E
R
L
E
E
G
-----
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
-------
L
V
I
D
E
D
--------
L
S
A
V
C
L
G
R
G
E
D
G
T
R
I
L
K
F
Q
--
P
Q
D
D
R
L
I
F
E
K
G
------------------------------------------------------
T
A
G
L
H
F
T
--------------------
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
-----------
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
--
V
G
T
T
T
V
R
T
L
E
T
I
A
R
----
L
P
E
--
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
-
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
------------
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
---
A
M
L
I
L
---------------------
21
Fugue
80.09
48%
-138
- C5 -
-
1VKY
1
QUEA_THEMA
A:
[16-347]
----------------------------------------------------
S
E
F
D
Y
E
L
P
P
E
L
I
A
Q
E
P
V
E
P
R
D
A
S
R
L
M
V
----------
L
H
R
K
T
Q
-
R
I
E
H
R
I
F
R
E
I
I
E
Y
L
E
P
G
--
D
L
L
V
L
N
V
S
K
V
I
P
A
---------------
R
L
Y
A
R
K
A
----
S
I
E
I
L
L
-
I
E
R
L
E
E
G
-----
I
W
K
C
L
V
R
P
G
Q
K
V
K
K
G
T
E
-------
L
V
I
D
E
D
--------
L
S
A
V
C
L
G
R
G
E
D
G
T
R
I
L
K
F
Q
---------------------------------------
P
Q
D
D
R
----------
L
I
F
E
K
-------
G
T
A
G
L
H
F
T
--------------------
P
E
L
I
E
K
L
K
K
K
G
V
Q
F
A
E
V
V
L
H
V
------------------
H
E
E
F
Y
-----------
Q
V
P
K
E
T
V
R
K
L
R
E
T
R
E
R
G
N
R
I
V
A
--
V
G
T
T
T
V
R
T
L
E
T
I
A
R
-----
L
P
E
-
Q
E
E
Y
V
G
K
T
D
L
F
I
Y
P
P
F
E
F
K
L
V
D
A
L
-
V
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
A
G
K
D
F
V
------------
M
E
A
Y
R
E
A
V
K
R
R
Y
R
F
F
S
F
G
D
---
A
M
L
I
L
---------------------
34
HHSearch
69.23
49%
-11
- C5 -
-
1WDI
1
QUEA_THET2
A:
[3-345]
--------------------------------------------------
G
L
E
A
Y
D
Y
H
L
P
P
E
Q
I
A
Q
E
G
V
E
P
R
D
M
A
R
L
M
V
----------
V
Y
R
E
G
P
F
R
V
A
H
K
R
V
R
D
L
P
E
F
L
R
P
G
--
D
V
L
V
F
N
E
S
K
V
I
P
A
---------------
R
L
L
A
R
K
-
P
T
G
G
K
V
E
I
L
L
-
V
R
E
R
-----------
A
L
L
G
P
A
R
K
A
P
P
G
T
R
-------
L
L
L
L
S
P
K
DLAPVPG
L
Q
A
E
V
V
A
V
E
E
D
------------
L
V
A
H
L
E
E
V
G
E
------------
V
P
------------------------------------
A
A
P
T
A
G
L
H
F
T
--------------------
P
E
L
L
E
R
L
R
E
M
G
V
E
L
R
F
L
T
L
H
V
G
P
G
T
F
R
P
----------
M
H
A
E
P
Y
-----------
A
I
P
E
E
V
A
E
A
V
N
R
A
K
A
E
G
R
R
V
V
A
--
V
G
T
T
V
V
R
A
L
E
S
A
Y
R
----
E
G
V
G
-
V
V
A
G
E
G
E
T
R
L
F
I
R
P
P
Y
T
F
K
V
V
D
A
L
-
F
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
L
G
R
E
R
T
------------
L
E
A
Y
R
L
A
V
A
E
G
Y
R
F
Y
S
L
G
D
---
A
M
L
I
L
---------------------
3
PsiBlast_PDB
67.82
48%
-11
- C5 -
-
1WDI
1
QUEA_THET2
A:
[5-344]
----------------------------------------------------
E
A
Y
D
Y
H
L
P
P
E
Q
I
A
Q
E
G
V
E
P
R
D
M
A
R
L
M
V
----------
V
Y
R
E
G
P
F
R
V
A
H
K
R
V
R
D
L
P
E
F
L
R
P
G
--
D
V
L
V
F
N
E
S
K
V
I
P
A
---------------
R
L
L
A
R
K
P
-
T
G
G
K
V
E
I
L
L
-
V
R
E
R
-----------
A
L
L
G
P
A
R
K
A
P
P
G
T
R
-------
L
L
L
L
S
P
K
DLAPVPG
L
Q
A
E
V
V
A
V
E
E
D
------------
L
V
A
H
L
E
E
V
G
E
------------
V
P
------------------------------------
A
A
P
T
A
G
L
H
F
T
--------------------
P
E
L
L
E
R
L
R
E
M
G
V
E
L
R
F
L
T
L
H
V
G
P
G
T
F
R
P
----------
M
H
A
E
P
Y
-----------
A
I
P
E
E
V
A
E
A
V
N
R
A
K
A
E
G
R
R
V
V
A
--
V
G
T
T
V
V
R
A
L
E
S
A
Y
R
E
---
G
V
G
--
V
V
A
G
E
G
E
T
R
L
F
I
R
P
P
Y
T
F
K
V
V
D
A
L
-
F
T
N
F
H
L
P
R
S
T
L
L
M
L
V
A
A
F
L
G
R
E
R
T
------------
L
E
A
Y
R
L
A
V
A
E
G
Y
R
F
Y
S
L
G
D
---
A
M
L
I
----------------------
30
Fugue
37.23
12%
-65
* C6 *
-
1F6Y
-
ACSE_MOOTH
A:
[1-262]
------------------------------------------------------------
M
L
I
I
G
E
R
I
N
G
M
F
G
D
I
K
R
A
I
----------
Q
E
R
D
P
A
-
P
V
Q
E
W
A
R
R
Q
E
E
G
G
A
R
A
L
--
D
L
N
V
G
D
K
V
S
A
M
E
W
---------------
L
V
E
V
T
Q
E
V
S
N
L
---
T
L
C
-
L
D
S
T
N
I
K
-----
A
I
E
A
G
L
K
K
C
K
N
R
A
M
I
N
S
-------
T
N
A
E
R
E
K
-------
V
E
K
L
F
P
L
A
V
E
H
G
A
A
L
I
G
L
---------------------------------------------------------
T
M
N
K
T
G
I
P
K
D
S
D
T
R
L
A
F
A
--------------------
M
E
L
V
A
A
A
D
E
F
G
L
P
M
E
D
L
Y
I
D
P
L
I
L
P
A
N
V
-----------
A
Q
D
H
A
-----------
P
E
V
L
K
T
L
Q
Q
I
K
M
L
A
D
P
A
P
K
T
V
L
--
G
-------
L
S
N
V
S
Q
N
---
C
Q
N
R
-
P
L
I
N
R
T
F
L
A
M
A
M
A
C
G
L
M
S
A
I
A
D
A
C
-
D
----------
E
A
L
I
E
T
A
A
T
A
E
I
L
------------
L
N
Q
T
V
Y
C
D
S
F
V
K
M
F
K
T
R
-------------------------------
50
HHSearch
36.91
14%
-160
- C5 -
-
3PVJ
-
?
D:
[237-257]
------------------------------------------------------------------------------------------------------------
R
W
Q
E
N
--
D
V
A
F
W
D
N
R
V
T
Q
H
F
---------------
A
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
34.45
14%
-157
- C5 -
-
3V17
1
?
B:
[237-257]
------------------------------------------------------------------------------------------------------------
R
W
Q
E
N
--
D
V
A
F
W
D
N
R
V
T
Q
H
F
---------------
A
V
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
33.46
36%
-196
- C5 -
-
1NX8
1
CARC_PECCC
B:
[235-256]
------------------------------------------------------------------------------------------------------------
F
W
E
D
G
--
D
L
L
I
M
D
N
R
R
V
I
H
E
---------------
R
E
E
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
33.17
27%
-211
- C5 -
-
2WBQ
-
ARGHX_STRVI
A:
[300-321]
------------------------------------------------------------------------------------------------------------
V
L
D
Q
G
--
D
V
A
F
I
D
N
R
R
A
V
H
G
---------------
R
R
A
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
32.69
18%
40
- C6 -
-
4IMP
1
?
A:
[31-550]
SD
P
A
A
G
W
F
W
Q
A
V
A
R
QD
L
K
S
V
S
D
A
L
DLDADAP
L
S
A
T
L
P
A
L
S
V
W
H
R
Q
E
R
E
R
V
L
A
D
G
W
R
Y
R
V
D
W
V
R
V
A
P
Q
P
V
R
R
T
R
E
T
W
L
L
V
V
P
PGGIE
E
A
L
V
E
R
L
T
D
-
A
L
N
T
R
G
I
S
T
L
R
L
D
V
P
P
A
AT
S
G
E
L
A
T
E
L
R
A
A
A
D
G
DPVK
A
I
L
S
LTALDE
R
P
H
P
E
C
K
D
V
P
S
G
I
A
L
L
L
N
L
V
K
A
L
G
E
A
DLR
I
P
L
W
T
I
T
R
G
A
V
K
A
G
P
A
D
R
LLR
P
M
Q
A
Q
A
W
G
L
G
R
-------
V
A
A
L
E
H
P
E
R
W
G
G
--
L
I
D
L
P
-
D
S
L
D
G
D
V
L
T
R
L
G
E
A
L
T
NGLAED
Q
L
A
I
R
Q
S
G
V
L
A
R
R
L
V
P
A
P
A
N
Q
PAGRK
W
R
P
R
G
S
A
L
I
T
G
G
L
G
A
V
G
A
Q
V
A
R
W
L
A
E
I
GAE
R
I
V
L
T
S
RRGNQAAG
A
A
E
L
E
A
E
L
R
A
L
G
A
Q
V
S
I
V
A
C
D
V
---
T
D
R
A
E
M
S
A
L
L
A
E
F
D
V
T
A
V
F
H
A
A
G
V
G
R
L
L
P
LA
E
T
D
Q
N
G
L
A
E
I
C
A
A
K
V
R
G
A
Q
V
L
D
E
L
C
D
S
T
D
L
D
A
F
V
L
F
S
S
G
AGV
W
G
G
G
-
G
Q
G
A
Y
G
A
A
N
A
F
L
D
T
L
A
E
Q
R
R
A
R
G
L
P
A
T
S
I
S
W
G
S
W
A
G
G
G
M
A
D
G
A
A
G
E
H
L
R
R
R
G
I
R
P
M
P
A
A
S
A
I
L
A
L
Q
E
V
L
D
Q
D
E
T
C
V
S
I
A
D
VD
W
D
R
F
V
P
T
F
A
A
TRATRLFDEV
P
A
A
R
K
AM
48
HHSearch
32.16
27%
-196
- C5 -
-
2WBO
1
ARGHX_STRVI
A:
[300-321]
------------------------------------------------------------------------------------------------------------
V
L
D
Q
G
--
D
V
A
F
I
D
N
R
R
A
V
H
G
---------------
R
R
A
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
31.41
38%
-124
- C7 -
-
2FZP
-
RNF41_HUMAN
A:
[202-237]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
N
S
L
Q
P
A
R
V
T
R
W
G
G
M
-------
I
S
T
P
D
A
V
-------
L
Q
A
V
I
K
R
S
L
V
E
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
31.36
22%
-209
- C5 -
-
2OG6
-
ASNO_STRCO
A:
[295-317]
------------------------------------------------------------------------------------------------------------
R
L
L
P
G
--
E
L
A
I
V
D
N
R
V
T
V
H
G
---------------
R
T
E
F
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
30.65
30%
-203
- C5 -
-
4M23
-
?
B:
[287-309]
------------------------------------------------------------------------------------------------------------
V
A
D
Q
G
--
D
V
L
F
I
D
N
H
R
A
V
H
G
---------------
R
L
P
F
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
30.35
38%
-89
- C7 -
-
2GWF
-
RNF41_HUMAN
B:
[202-237]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
N
S
L
Q
P
A
R
V
T
R
W
G
G
M
-------
I
S
T
P
D
A
V
-------
L
Q
A
V
I
K
R
S
L
V
E
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------