@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYT0: (2017-12-15 )
MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKSEFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIIDSLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTEYGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ
Atome Classification :
(20 SA)
-------------------------------------------------------------....--.....10.-.......20-.......----------.30-------------.........40........50.....----------...60..---------......--70--....-.....80........-90....--.--.-..100.....-------------..110....--...120-......-.----130-....-----...140----------....-------...150..--------------.....-160.---......170.-..-----....180....------...190.......200.........210....------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------MNDE--YKN
D
E
D
K
M
-
L
F
E
E
I
E
N
R
C
-
R
L
N
F
E
LR----------
G
K
--------------
M
S
L
I
Q
Q
K
K
Y
LANKSEF
T
L
G
H
V
E
K
L
I
S
----------
D
W
I
S
S
R
S
---------
E
F
T
K
I
K--Q---
P
I
K
F
-
D
M
K
K
L
LL
N
K
S
EIGNR-
D
Q
Y
I
R
A--K--
G
-
Q
E
I
I
D
S
L
G
EM-------------RSY
N
Y
L
Y
V
T
--HRAD
G
M
-
V
I
T
VGK-S----SSN-
D
I
F
L-----DG
D
L
F
Y
----------
Q
L
NT-------NHLSGT
E
N
--------------
I
I
L
R
T-EYG
N
---
E
I
F
A
K
Y
D
E
I
L
-
K
N
-----YLD
W
A
W
I
I
PVE------SG
D
A
K
K
L
E
R
L
L
G
D
E
--
L
INKKVPILNYYSHRQ------------
33
Fugue
65.20
15%
33
- C6 -
-
4NFA
3
A:
[1-207]
----------------------------------------------------------SLS
E
W
D
V
--
V
E
W
S
D
D
Q
A
-
V
F
T
F
V
Y
D
T
I
-
Q
L
T
I
T
F
E
ESVVGFPFLD
K
R
--------------
Y
R
K
I
V
D
V
N
F
Q
S
L
L
D
E
D
Q
A
P
P
S
S
L
L
V
H
----------
K
L
I
F
Q
Y
V
---------
E
E
K
E
S
W
--
K
---
T
T
Q
H
-
Q
L
P
K
M
L
---
E
E
F
S
L
V
-
V
H
H
C
R
L
--
L
--
G
-
E
E
I
E
Y
L
K
R
W
G
-------------
P
N
Y
N
L
M
N
I
D
--
I
N
N
N
E
L
-
R
L
L
F
S
S
-
S
----
A
A
F
-
A
K
F
--------
E
I
T
L
----------
F
L
S
A
-------
Y
Y
P
S
V
P
L
P
--------------
S
T
I
Q
N
-
H
V
G
N
---
T
S
Q
D
D
I
A
T
I
L
-
S
K
------------
V
P
L
E
------
N
N
Y
L
K
N
V
V
K
Q
I
Y
Q
D
--
L
F
Q
D
------------------------
32
Fugue
54.74
19%
99
* C6 *
-
3L0I
-
DRRA_LEGPH
A:
[23-347]
SFSN
M
V
S
A
K
K
F
Y
N
K
A
IFTAPKAEVSVKTHI
M
R
P
I
D
F
M
L
M
G
L
R
E
E
F
NLYSEDHLS
A
P
G
T
I
R
L
L
R
E
K
--
N
L
L
P
E
E
Q
I
A
R
I
E
S
V
Y
N
Q
A
M
S
K
R
F
E
L
H
----------
A
E
HEHDEMPYSDA
K
A
M
L
D
E
V
A
K
I
R
E
L
G
V
Q
R
V
T
R
I
E
N
L
E
N
A
K
K
----------
L
W
D
N
A
N
S
M
L
E
K
GN
I
S
G
Y
L
K
A
A
N
--
E
---
L
H
K
F
M
K
E
K
N
L
K
E
D
D
L
R
P
E
L
S
-
D
K
T
I
S
P
--
K
--
G
-
Y
A
I
L
Q
S
L
W
G
A
A
S
D
Y
S
--------
R
A
A
A
T
L
T
E
S
--
T
V
E
P
G
L
-
V
S
A
V
N
K
M
S
----
A
F
F
M
D
C
K
L
-----
S
P
N
E
R
A
----------
T
P
D
P
-------
D
F
K
V
G
K
S
K
--------------
I
L
V
G
I
M
Q
F
I
K
---
D
V
A
D
P
T
S
K
I
W
M
H
N
T
K
A
L
M
N
H
K
I
A
A
I
Q
K
L
E
------
R
S
N
N
V
N
-
D
E
T
L
E
S
V
--
L
S
S
K
G
E
N
L
S
E
Y
L
S
Y
K
Y
------------
29
Fugue
53.13
18%
63
- C2 -
-
5H3W
-
?
A:
[1-281]
------------------------------------------------------------D
R
V
A
Q
--
Q
A
N
E
L
I
K
R
-
V
A
S
E
L
E
K
N
R
-
K
K
L
I
K
Q
E
----------
Q
E
--------------
L
A
D
T
E
T
A
E
L
V
R
Q
K
G
E
L
L
S
Q
N
A
Q
R
Y
F
K
----------
K
Y
Q
K
L
K
E
---------
A
V
K
H
L
T
--
N
---
L
I
E
E
-
T
K
S
T
I
V
Y
L
E
S
V
D
T
M
L
-
G
Q
A
S
L
A
--
E
--
I
-
D
E
I
R
E
E
L
I
E
T
GYLKRRHR
E
K
I
H
K
R
Q
K
P
E
R
Y
L
A
--
T
--
D
G
K
T
I
I
L
V
G
K
N
N
----
L
Q
N
-
D
E
L
T
FKMAK
K
G
E
L
W
F
----------
H
A
K
D
I
P
G
----
S
H
V
V
I
T
D
N
--------------
L
D
P
S
D
-
E
V
K
T
D
A
A
E
L
A
A
Y
F
S
K
A
R
-
H
S
-----
N
L
-----
V
Q
V
D
------
M
I
E
A
K
K
L
H
K
P
T
G
G
K
PG
F
V
T
Y
R
G
Q
K
T
L
R
V
T
P
T
E
D
K
I
K
S
M
KI----
27
Fugue
52.70
13%
2
- C1 -
-
3A25
-
TYW2_PYRHO
A:
[29-301]
-------------------------------------------------------------
I
K
P
R
--
I
R
E
I
L
S
K
E
-
L
P
E
E
L
V
K
L
L
-
P
K
R
W
V
R
I
----------
G
D
--------------
V
L
L
L
P
L
R
P
E
L
E
P
Y
K
H
R
I
A
E
V
Y
A
E
V
L
G
VKTVLRKGDY
E
L
L
Y
G
S
D
---------
T
V
T
V
H
V
--
E
NG
I
K
Y
K
L
-
D
V
A
K
I
M
F
S
P
A
N
V
K
E
R
-
V
R
M
A
K
V
AK
P
--
D
-
E
L
V
V
D
M
F
A
G
I
-------------
G
H
L
-
S
L
P
I
A
--
V
Y
G
K
A
K
-
V
I
A
I
E
K
-
D
----
P
Y
T
-
F
K
F
L
-----
V
E
N
I
H
L
----------
N
K
V
E
-------
D
R
M
S
A
Y
N
M
DNRDFPGENIAD
R
I
L
M
G
Y
V
-
V
R
T
H
---
E
F
I
P
K
A
L
S
I
A
-
K
D
G
A
---
I
I
H
Y
H
N
T
V
P
E
K
LMPRE
P
F
E
T
F
K
R
I
T
K
E
Y
G
Y
D
--
V
E
K
L
N
E
L
K
I
K
R
Y
A
P
G
V
W
H
V
V
L
D
L
R
V
F
KS
7
PsiBlast_PDB
51.89
26%
30
- C7 -
-
4C5N
2
?
A:
[125-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
-
N
L
F
E
A
G
--
Q
L
S
G
-
L
G
K
L
N
S
I
E
D
M
-------------
K
K
A
A
T
I
I
F
D
--
K
G
A
Q
H
V
-
I
I
K
G
G
K
-
A
LDQD
K
S
Y
-
D
L
Y
Y
-----
D
G
Q
T
F
Y
----------
Q
L
T
T
D
MFQQSY
N
H
G
A
G
C
T
F
--------------
A
A
A
T
T
-
A
Y
------------------------------------------------------------------------------------
31
Fugue
51.01
18%
-22
* C5 *
-
5TJ5
-
VATO_YEAST
B:
[1-213]
-------------------------------------------------------------
M
N
K
E
--
S
K
D
D
D
M
S
L
-
G
K
F
S
F
S
H
F
L
-
Y
Y
---
V
Y
----------
G
L
--------------
Y
K
L
F
T
G
H
G
S
D
I
N
F
G
K
F
L
L
R
T
S
P
Y
M
-------------
W
A
N
L
G
I
---------
A
L
C
V
G
L
--
S
---
V
V
G
A
-
A
W
G
I
F
I
T
G
S
S
M
I
G
A
G
-
V
R
A
P
R
I
--
T
--
T
-
K
N
L
I
S
I
I
F
C
E
-------------
V
V
A
I
Y
----------
G
L
-
I
I
A
I
V
F
-
S
----
S
K
S
-
N
L
Y
T
-----
G
Y
S
L
F
W
----------
A
G
I
T
----------
V
G
A
S
N
--------------
L
I
C
G
I
-
A
V
G
I
---
T
G
A
T
A
A
I
S
F
V
-
K
I
-----
L
V
I
E
I
F
------------
G
S
I
L
G
L
L
G
L
I
V
G
L
--
L
M
A
G
K
A
S
E
F
Q
------------------
4
PsiBlast_PDB
50.80
26%
22
- C7 -
-
4C5K
1
?
A:
[125-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
-
N
L
F
E
A
G
--
Q
L
S
G
-
L
G
K
L
N
S
I
E
D
M
-------------
K
K
A
A
T
I
I
F
D
--
K
G
A
Q
H
V
-
I
I
K
G
G
K
-
A
LDQD
K
S
Y
-
D
L
Y
Y
-----
D
G
Q
T
F
Y
----------
Q
L
T
T
D
MFQQSY
N
H
G
A
G
C
T
F
--------------
A
A
A
T
T
-
A
Y
------------------------------------------------------------------------------------
6
PsiBlast_PDB
50.43
26%
19
- C7 -
-
4C5M
1
?
A:
[125-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
-
N
L
F
E
A
G
--
Q
L
S
G
-
L
G
K
L
N
S
I
E
D
M
-------------
K
K
A
A
T
I
I
F
D
--
K
G
A
Q
H
V
-
I
I
K
G
G
K
-
A
LDQD
K
S
Y
-
D
L
Y
Y
-----
D
G
Q
T
F
Y
----------
Q
L
T
T
D
MFQQSY
N
H
G
A
G
C
T
F
--------------
A
A
A
T
T
-
A
Y
------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.89
26%
21
- C7 -
-
4C5J
-
?
A:
[125-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
-
N
L
F
E
A
G
--
Q
L
S
G
-
L
G
K
L
N
S
I
E
D
M
-------------
K
K
A
A
T
I
I
F
D
--
K
G
A
Q
H
V
-
I
I
K
G
G
K
-
A
LDQD
K
S
Y
-
D
L
Y
Y
-----
D
G
Q
T
F
Y
----------
Q
L
T
T
D
MFQQSY
N
H
G
A
G
C
T
F
--------------
A
A
A
T
T
-
A
Y
------------------------------------------------------------------------------------
26
Fugue
48.54
19%
-27
- C3 -
-
2MN4
-
?
A:
[1-94]
--------------------------------------------------------------------------
M
-
T
P
E
Q
R
E
F
L
P
-
E
I
L
A
E
I
I
----------
A
N
--------------
L
D
P
T
K
I
L
E
E
L
L
R
R
G
L
L
T
P
A
E
L
Q
E
V
L
D
----------
L
----
K
T
---------
P
E
E
Q
A
K
--
K
---
L
I
D
F
-
I
L
K
---
L
S
P
A
D
V
Q
A
R
-
I
N
V
L
R
A
--
H
--
G
Y
Q
A
L
A
D
K
L
N
K
Y
-------------
L
T
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
47.56
24%
66
* C8 *
-
2MPW
-
EAE_ECO27
A:
[39-153]
-------------------------------------------------------------
M
N
G
E
NY
F
K
L
G
S
D
S
K
-
L
L
T
H
N
S
Y
Q
N
-
R
L
F
Y
T
L
K
----------
T
G
--------------
E
T
----
V
A
D
L
S
K
S
Q
D
I
N
L
S
T
I
W
S
L
N
K
----------
H
L
Y
S
S
E
S
---------
E
M
M
K
A
A
PG
Q
---
Q
I
I
L
-
P
L
K
K
L
P
F
E
Y
S
A
L
P
L
L
G
S
A
P
L
V
A
--
A
--
G
-
G
V
A
G
H
T
N
G
S
G
-------------
S
E
N
L
Y
F
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
47.17
26%
21
- C7 -
-
4C5L
1
?
A:
[125-223]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
Y
L
L
P
K
A
T
V
V
T
P
-
N
L
F
E
A
G
--
Q
L
S
G
-
L
G
K
L
N
S
I
E
D
M
-------------
K
K
A
A
T
I
I
F
D
--
K
G
A
Q
H
V
-
I
I
K
G
G
-------
K
S
Y
-
D
L
Y
Y
-----
D
G
Q
T
F
Y
----------
Q
L
T
T
D
MFSY--
N
H
G
A
G
C
T
F
--------------
A
A
A
T
T
-
A
Y
------------------------------------------------------------------------------------
25
HHSearch
45.20
25%
-145
- C7 -
-
3VU7
-
H:
[37-64]
---------------------------------------------------------------------------------------------------------------------------------------
E
F
N
D
V
K
T
L
L
R
----------
E
W
I
T
T
I
S
-----------------
D
---
P
M
E
E
-
D
I
L
Q
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
43.36
32%
-143
- C7 -
-
4BK2
1
?
A:
[349-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
R
I
L
T
-----
T
G
R
M
W
G
----------
E
L
W
---------
H
L
D
G
T
A
R
--------------
I
A
R
------
N
---
E
L
F
R
T
R
D
T
S
S
-
Y
K
-----
Y
T
D
W
L
W
--
G
Y
S
------
S
D
R
-----------------------------------------
2
PsiBlast_PDB
43.21
38%
-239
- C7 -
-
4N6K
-
?
A:
[234-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
-------
R
H
I
L
G
T
C
G
--------------
V
Y
I
S
T
-
K
V
W
N
---
D
I
P
A
K
Y
Q
K
I
I
-
Q
D
------------------------------------------------------------------
8
PsiBlast_PDB
42.80
32%
-150
- C7 -
-
4BJY
1
?
A:
[349-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
R
I
L
T
-----
T
G
R
M
W
G
----------
E
L
W
---------
H
L
D
G
T
A
R
--------------
I
A
R
------
N
---
E
L
F
R
T
R
D
T
S
S
-
Y
K
-----
Y
T
D
W
L
W
--
G
Y
S
------
S
D
R
-----------------------------------------
35
Fugue
42.75
10%
-30
- C5 -
-
2WLG
10
OATWY_NEIME
A:
[5-215]
--------------------------------------------------------------
M
Y
S
--
E
Q
G
I
N
N
T
I
-
N
I
S
T
T
S
L
T
N
-
A
T
Q
L
T
V
I
----------
G
N
--------------
N
N
S
V
Y
I
G
N
N
C
K
I
V
S
S
-
N
I
R
L
K
G
N
N
I
T
----------
L
F
I
A
D
D
V
---------
E
I
M
G
L
V
--
C
---
S
L
H
S
-
D
C
S
L
Q
I
Q
A
K
T
T
M
G
N
G
-
E
I
T
I
A
E
--
K
--
G
-
K
I
S
I
G
K
D
C
M
L
-------------
A
H
G
Y
E
I
R
N
T
DM
H
P
I
Y
S
L
-
E
N
G
E
R
I
-
N
----
H
G
K
-
D
V
I
I
-----
G
N
H
V
W
L
G
R
N
V
T
I
L
K
G
V
C
I
P
N
-------
N
V
V
V
G
S
H
T
--------------
V
L
Y
K
S
-
F
K
E
P
---
N
C
V
I
A
G
S
P
A
----------------
K
I
V
K
------
E
N
I
V
W
G
R
K
M
Y
H
S
T
M
--
Y
D
D
P
T
L
--
N
E
F
Y
K
---------------
11
PsiBlast_PDB
42.47
32%
-135
- C7 -
-
4BK1
1
?
A:
[349-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
R
I
L
T
-----
T
G
R
M
W
G
----------
E
L
W
---------
H
L
D
G
T
A
R
--------------
I
A
R
------
N
---
E
L
F
R
T
R
D
T
S
S
-
Y
K
-----
Y
T
D
W
L
W
--
G
Y
S
------
S
D
R
-----------------------------------------
17
HHSearch
42.16
25%
-84
- C7 -
-
4EXT
-
A:
[9-36]
---------------------------------------------------------------------------------------------------------------------------------------
E
F
N
D
V
K
T
L
L
R
----------
E
W
I
T
T
I
S
-----------------
D
---
P
M
E
E
-
D
I
L
Q
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.11
32%
-135
- C7 -
-
4BJZ
1
?
A:
[349-397]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
R
I
L
T
-----
T
G
R
M
W
G
----------
E
L
W
---------
H
L
D
G
T
A
R
--------------
I
A
R
------
N
---
E
L
F
R
T
R
D
T
S
S
-
Y
K
-----
Y
T
D
W
L
W
--
G
Y
S
------
S
D
R
-----------------------------------------