@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZ02: (2017-12-15 )
MKVGKMMFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEISTTQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRADAARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30.......--------.40........50...-------------..-...60........70.--------------..--......80..-.....-.90----------.........100.......110..----......120.......130.......140---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK
V
G
K
M
M
F
G
F
F
K
K
KEK
E
P
K
K
V
L
A
K
E
E
KALS
P
E
A
T
E
K
I
Q
--------
S
E
I
T
Q
L
K
Q
E
I
S
T
T
Q
D
K
-------------
H
K
-
L
A
K
L
Y
E
Q
VG
L
K
F
S
E
-
L
--------------
Y
V--
N
D
Q
A
I
Q
Y
L
E
K
-
S
LENK-QT-----------
I
G
D
G
Y
K
K
L
M
S
L
Y
N
Q
K
RADAAR-AG----DDQ
G
I
D
Y
Y
MG
K
M
D
E
M
R
Q
I
A
K
Q
VTIKGNK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
62.20
14%
-37
- C2 -
-
4EQF
-
A:
[75-189]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
E
G
D
L
P
--------
V
T
I
L
F
M
E
A
A
I
-
L
--
Q
D
-------------
P
G
-
D
A
E
A
W
Q
F
L
G
I
T
Q
A
E
-
N
--------------
E
N
--
E
Q
A
A
I
V
A
L
Q
R
-
C
L
E
L
Q
-
P
N
-----------
N
L
K
A
L
M
A
L
A
V
S
Y
T
N
T
S
H
Q
-----------
Q
D
A
C
E
A
L
K
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
62.06
19%
119
- C2 -
-
4UZY
-
?
A:
[9-650]
QQPA
R
P
I
A
EGQ
Y
T
Q
T
I
Y
T
L
I
K
E
QK
F
A
E
A
I
Q
H
L
Q
Y
Q
L
Q
N
V
P
ES
R
A
A
L
S
L
L
G
Y
C
Y
Y
Y
T
GQ
Y
D
M
A
S
Q
M
Y
E
Q
L
V
T
L
Y
P
SN
E
D
Y
K
L
Y
Y
A
Q
S
L
Y
K
G
GM
Y
P
E
A
S
K
A
V
V
K
VEGH
Q
K
A
V
T
T
L
L
V
A
C
S
Y
E
Q
DD
L
T
G
C
R
R
Q
L
D
K
CAPED
P
D
T
M
V
N
T
G
C
I
M
F
K
E
GK
F
E
A
A
R
Q
K
F
N
DYQ
P
E
L
L
Y
N
I
A
L
C
Y
Y
K
TKQ
F
G
P
A
L
K
H
L
A
E
I
I
E
K
A
V
R
E
HPELSVGSDGMEVRSVGNS
Q
T
L
K
E
T
A
L
I
E
A
F
N
L
K
A
A
I
E
Y
T
M
KN
V
E
A
A
K
E
A
L
T
D
MPPRAEEELD
P
V
T
L
H
N
S
A
L
I
N
M
DSD
P
T
G
G
F
K
K
L
N
F
L
L
Q
S
PPFPPE
T
F
A
N
L
L
L
L
Y
C
K
P
S
H
G
F
Y
D
L
A
A
D
V
L
A
E
N
P
Q
Y
A
G
K
L
L
S
P
D
L
Y
D
Y
L
Q
--------
A
A
I
G
R
Y
K
S
----------------------------
P
E
E
A
F
R
R
F
D
E
-
L
--------------
A
T
R
-
H
V
E
Q
L
R
R
L
T
K
-
Q
I
Q
D
A
-
R
I
-----------
A
R
D
----------
N
D
A
I
K
R
A
I
-
N
E
----
Y
D
E
A
L
E
A
Y
I
P
G
L
M
A
M
A
S
I
Y
W
D
M
E
L
Y
S
N
V
E
K
I
F
R
Q
S
AEFCSEH
E
V
W
K
L
N
V
A
H
T
F
F
M
Q
DNH
Y
K
E
A
I
R
Y
Y
E
P
V
V
K
K
N
A
DNLLGVT
A
I
V
L
A
N
L
C
V
S
Y
I
M
T
SQ
N
E
E
A
E
E
L
M
R
K
V
E
K
E
E
E
R
S
S
M
Q
DPDKPCF
H
L
C
I
I
N
L
V
I
G
T
L
Y
C
A
K
GN
Y
E
F
G
V
S
R
I
I
K
S
L
EE
T
D
T
W
Y
Y
A
K
R
C
F
L
A
L
I
E
N
L
A
K
H
MIVLK
D
S
S
F
T
E
I
M
A
F
L
N
E
A
E
K
H
G
K
D
I
R
V
V
F
NQSRT
I
A
S
E
A
R
M
L
K
K
M
F
L
K
L
R
40
HHSearch
62.04
11%
-24
- C2 -
-
3FP2
-
TOM71_YEAST
A:
[36-142]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
A
K
N
F
N
---------
A
I
K
Y
Y
Q
Y
A
I
-
E
--
L
D
-------------
P
N
-
E
P
V
F
Y
S
N
I
S
A
C
Y
I
S
-
T
--------------
G
D
--
L
E
K
V
I
E
F
T
T
K
-
A
L
E
I
K
-
P
D
-----------
H
S
K
A
L
L
R
R
A
S
A
N
E
S
L
G
N
F
-----------
T
D
A
M
F
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
60.57
13%
-33
- C2 -
-
3IEG
-
DNJC3_MOUSE
B:
[47-131]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
A
A
G
Q
L
A
--------
D
A
L
S
Q
F
H
A
A
V
-
D
--
G
D
-------------
P
D
-
N
Y
I
A
Y
Y
R
R
A
T
V
F
L
A
-
M
--------------
G
K
--
S
K
A
A
L
P
D
L
T
K
-
V
I
A
L
K
-
M
D
-----------
F
T
A
A
R
L
Q
R
G
H
L
L
L
K
Q
G
K
L
-----------
D
E
A
E
D
D
F
K
K
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
60.43
7%
-35
- C2 -
-
2C0L
-
PEX5_HUMAN
A:
[535-631]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
Q
S
E
--------
E
A
V
A
A
Y
R
R
A
L
-
E
--
L
Q
-------------
P
G
-
Y
I
R
S
R
Y
N
L
G
I
S
C
I
N
-
L
--------------
G
A
--
H
R
E
A
V
E
H
F
L
E
-
A
L
N
M
Q
-
R
K
SRGP
R
G
E
G
G
A
M
S
E
N
I
W
S
T
L
R
L
A
L
S
M
L
G
Q
S
-----------
D
A
Y
G
A
A
D
A
R
D
L
S
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
59.36
17%
118
- C2 -
-
5GOX
2
RAD50_HUMAN
A:
[5-185]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K
E
I
N
Q
T
R
D
R
L
A
K
L
N
K
E
L
A
S
S
E
Q
N
K
N
H
I
N
N
E
L
K
R
K
E
E
Q
L
S
S
Y
E
D
K
L
F
D
V
CGSQDF
E
S
D
L
D
R
L
K
E
E
I
E
K
S
S
K
Q
-------------
R
A
M
L
A
G
A
T
A
V
Y
S
Q
F
I
T
Q
-
L
TDENQSCCPVCQRV
F
Q
--
T
E
A
E
L
Q
E
V
I
S
-
D
L
Q
S
K
L
R
L
-----------
A
P
D
K
L
K
S
T
E
S
E
L
K
K
K
E
K
R
R
D
E
M
L
G
L
V
P
M
R
Q
S
I
I
D
L
K
E
K
E
I
P
E
L
R
N
K
L
Q
N
V
N
R
D
I
Q
R
L
K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
58.05
9%
-40
* C2 *
-
3WXX
-
?
E:
[36-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
H
A
G
K
H
D
--------
E
A
H
K
I
F
Q
A
L
C
-
V
--
L
D
-------------
H
Y
-
E
A
R
F
F
L
G
L
G
A
C
R
Q
A
-
L
--------------
G
Q
--
F
R
L
A
I
D
S
Y
S
Y
-
G
A
M
M
D
-
L
Q
-----------
E
P
R
F
P
F
H
A
A
E
C
L
L
Q
L
G
E
L
-----------
E
G
A
E
S
G
F
H
S
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
57.91
13%
58
- C2 -
-
5L0Y
-
?
A:
[19-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
R
K
Q
R
Y
G
--------
D
A
I
K
L
Y
T
L
G
L
-
Q
--
M
A
L
T
RPAWEPAG
L
V
R
D
E
-
I
H
Q
L
Y
S
N
R
A
Q
A
Y
M
Q
-
L
--------------
G
Q
--
W
P
E
A
A
A
D
A
E
C
-
S
V
E
A
K
R
Q
G
-----------
N
A
K
A
W
Y
R
R
G
K
C
L
M
E
M
R
R
L
-----------
Q
E
A
R
E
W
V
A
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
57.71
12%
-94
- C2 -
-
5JJX
-
SART3_HUMAN
A:
[11-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
E
K
N
Q
--------
L
E
I
E
R
L
E
E
Q
L
-
S
--
I
N
-------------
V
Y
-
D
Y
N
C
H
V
D
L
I
R
L
L
R
L
-
E
--------------
G
E
--
L
T
K
V
R
M
A
R
Q
K
-
M
S
E
I
F
-
P
L
-----------
T
E
E
L
W
L
E
W
L
H
D
E
I
S
M
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
57.53
13%
-41
- C2 -
-
4CGQ
-
TAH1_YEAST
A:
[15-91]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
Q
G
L
Y
R
--------
E
A
V
H
C
Y
D
Q
L
I
-
T
--
A
Q
-------------
P
Q
-
N
P
V
G
Y
S
N
K
A
M
A
L
I
K
-
L
--------------
G
E
--
Y
T
Q
A
I
Q
M
C
Q
Q
-
G
L
R
Y
T
-
S
T
-----------
A
E
H
V
-
A
I
R
S
K
L
Q
Y
R
L
E
L
A
Q
G
A
V--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
57.43
22%
6
- C2 -
-
2B8I
-
?
A:
[1-77]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
P
Y
M
K
A
L
I
Y
--------
E
T
L
V
N
L
A
N
Q
-
D
P
E
Q
H
A
-------------
T
I
-
R
Q
N
L
Y
E
Q
L
D
L
P
F
D
K
Q
L
--------------
A
L
--
Y
A
G
A
L
G
P
A
S
S
G
K
L
E
N
H
-
E
A
-----------
I
S
N
A
V
D
S
V
V
Q
L
L
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
54.07
32%
-4
- C2 -
-
4WNE
-
GPSM2_HUMAN
A:
[48-100]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
53.79
32%
-18
- C2 -
-
5A6C
-
AFAD_HUMAN (first)
A:
[34-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.64
32%
-12
- C2 -
-
4G2V
2
GPSM2_MOUSE
A:
[38-91]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
52.60
32%
2
- C2 -
-
3SF4
-
GPSM2_HUMAN
A:
[48-97]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.31
32%
-3
- C2 -
-
4WNG
-
GPSM2_HUMAN
A:
[48-97]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
52.16
32%
8
- C2 -
-
4WNF
-
GPSM2_HUMAN
A:
[48-91]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
51.84
18%
16
- C1 -
-
2WBX
-
CAD23_MOUSE
A:
[1-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
V
N
R
L
P
--
F
F
T
N
H
F
F
D
T
Y
L
L
I
S
E
D
T
P
---------
V
G
--------
S
S
V
T
Q
L
L
-----
A
R
D
M
-------------
D
N
-
D
P
L
V
F
G
V
S
G
E
E
A
S
R
-
F
--------------
F
A
VE
P
D
T
G
V
V
W
L
R
Q
-
P
L
D
R
E
-
T
-----------------------------------------
K
S
E
F
T
V
E
F
S
V
S
D
H
Q
G
V
I
T
R
K
V
N
I
Q
V
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
50.82
7%
-5
- C2 -
-
4I17
1
?
A:
[16-102]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
L
N
A
K
N
Y
A
--------
V
A
F
E
K
Y
S
E
Y
L
-
K
--
L
T
-------------
N
N
Q
D
S
V
T
A
Y
N
C
G
V
C
A
D
N
-
I
--------------
K
K
--
Y
K
E
A
A
D
Y
F
D
I
-
A
I
K
K
N
-
Y
N
-----------
L
A
N
A
Y
I
G
K
S
A
A
Y
R
D
M
K
N
N
-----------
Q
E
Y
I
A
T
L
T
E
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
50.61
32%
9
- C2 -
-
3RO2
1
GPSM2_MOUSE
A:
[36-82]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
D
L
-------------
K
T
-
L
S
A
I
Y
S
Q
L
G
N
A
Y
F
Y
-
L
--------------
H
D
--
Y
A
K
A
L
E
Y
H
H
H
-
D
L
T
L
A
-
R
T
-----------
I
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------