@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZ89: (2017-12-16 )
MNMVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAAKEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNADSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSDAVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQLILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGYDNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTAPLK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.-......150......-.-160.......170.......180.......190.-...-...200........210.......-220........230.......240.--..--......250.......260.......270.......280.......290.......300.......310.......320.---......330.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNM
V
K
K
K
I
T
I
K
E
V
A
K
LSG
V
S
I
T
T
V
S
L
I
LNGNTEKF
S
P
K
T
V
Q
K
V
L
A
A
K
E
ELGYQ
P
D
Y
F
A
R
Q
M
I
TKET
K
T
I
G
V
LVPDIT
N
P
F
F
S
T
L
M
R
G
I
E
D
I
L
YKQ
N
F
V
T
I
L
CNADS
D
H
Q
K
E
I
E
Y
L
A
E
L
T
RRGV
D
G
F
I
I
A
TSAV
S
T
D
A
I
N
E
N
L
K
-KQGR
P
F
I
V
L
DQKKSE-G-FSDAVRTDDFR
G
G
Y
L
A
G
M
H
L
L
SLG
H
Q
T
I
A
L
V
YPE-NPP-
E
N
V
H
A
-
R
I
E
G
F
K
S
A
L
D
V
YQIPHD
Q
-
L
-
I
L
LPTQFSKQG
G
Y
Q
I
T
A
E
L
L
--
D
--SA--AT
G
V
F
A
LN
D
E
L
A
F
G
L
Y
R
G
L
E
E
A
G
K
SIPED
Y
S
I
IGYDNI
D
M
C
E
Y
I
K
P
K
L
T
T
I
A
Q
P
I
F
E
L
G
Q
T
S
A
K
L
L
L
D
R
IQF
P
E
K
E
W
E
EK---RLP
V
R
L
E
K
RFSTAPLK
1
PsiBlast_PDB
86.40
98%
-96
- C1 -
-
4RK1
1
?
A:
[8-280]
------------------------------------------------------------------
K
T
I
G
V
L
V
P
D
I
T
N
P
F
F
S
T
L
M
R
G
I
E
D
I
L
Y
K
Q
N
F
V
T
I
L
C
N
A
D
------
I
E
Y
L
A
E
L
T
R
R
G
V
D
G
F
I
I
A
T
S
A
V
S
T
D
A
I
N
E
N
L
K
-
K
Q
G
R
P
F
I
V
L
D
Q
K
K
S
E
-
G
-
F
S
D
A
V
R
T
D
D
F
R
G
G
Y
L
A
G
M
H
L
L
S
L
G
H
Q
T
I
A
L
V
Y
P
E
-
N
P
P
-
E
N
V
H
A
-
R
I
E
G
F
K
S
A
L
D
V
Y
Q
I
P
H
D
Q
-
L
-
I
L
L
P
T
Q
F
S
K
Q
G
G
Y
Q
I
T
A
E
L
L
--
D
--
S
A
--
A
T
G
V
F
A
L
N
D
E
L
A
F
G
L
Y
R
G
L
E
E
A
G
K
S
I
P
E
D
Y
S
I
I
G
Y
D
N
I
D
M
C
E
Y
I
K
P
K
L
T
T
I
A
Q
P
I
F
E
L
G
Q
T
S
A
K
L
L
L
D
R
I
Q
F
P
E
K
E
W
E
E
K
---
R
L
P
V
R
F
E
K
R
F
S
T
A
P
L
K
2
PsiBlast_PDB
74.45
61%
-97
- C1 -
-
4RK0
1
?
A:
[7-274]
-----------------------------------------------------------------
S
K
T
I
G
V
I
V
P
D
I
T
N
P
F
F
A
Q
L
I
R
G
I
E
S
V
L
Y
K
E
N
F
I
L
I
L
C
N
A
D
Q
D
V
T
R
E
H
E
Y
L
T
E
L
I
R
R
S
V
D
G
F
V
I
A
S
S
E
I
S
N
Q
T
I
N
E
T
L
R
-
A
K
K
I
P
F
I
V
L
D
Q
K
K
A
E
-
G
-
F
S
D
A
V
L
T
D
D
Y
R
G
G
Q
L
A
A
K
H
L
Q
E
Q
R
H
E
Q
V
I
V
V
M
P
P
-
H
A
P
-
V
N
I
Q
Q
-
R
L
K
G
F
C
S
---
V
Y
T
---
E
K
-
V
-
Q
L
I
E
T
E
L
S
K
T
G
G
Y
Q
A
V
P
E
I
L
--
K
--
T
E
--
S
T
G
I
F
A
I
N
D
E
I
A
F
G
L
Y
R
G
L
A
E
A
G
K
K
I
P
E
D
Y
S
I
I
G
Y
D
N
V
D
M
C
E
Y
V
S
P
P
L
T
T
I
A
Q
P
V
F
Q
L
G
Q
T
T
A
T
L
L
L
E
R
I
H
Q
P
A
K
D
W
E
E
Q
---
T
L
P
V
Q
L
I
E
R
F
S
T
A
P
L
K
21
PsiBlast_CBE
74.01
61%
-98
- C1 -
-
4RK0
1
?
D:
[6-274]
----------------------------------------------------------------
K
S
K
T
I
G
V
I
V
P
D
I
T
N
P
F
F
A
Q
L
I
R
G
I
E
S
V
L
Y
K
E
N
F
I
L
I
L
C
N
A
D
Q
D
V
T
R
E
H
E
Y
L
T
E
L
I
R
R
S
V
D
G
F
V
I
A
S
S
E
I
S
N
Q
T
I
N
E
T
L
R
-
A
K
K
I
P
F
I
V
L
D
Q
K
K
A
E
-
G
-
F
S
D
A
V
L
T
D
D
Y
R
G
G
Q
L
A
A
K
H
L
Q
E
Q
R
H
E
Q
V
I
V
V
M
P
P
-
H
A
P
-
V
N
I
Q
Q
-
R
L
K
G
F
C
S
---
V
Y
T
---
E
K
-
V
-
Q
L
I
E
T
E
L
S
K
T
G
G
Y
Q
A
V
P
E
I
L
--
K
--
T
E
--
S
T
G
I
F
A
I
N
D
E
I
A
F
G
L
Y
R
G
L
A
E
A
G
K
K
I
P
E
D
Y
S
I
I
G
Y
D
N
V
D
M
C
E
Y
V
S
P
P
L
T
T
I
A
Q
P
V
F
Q
L
G
Q
T
T
A
T
L
L
L
E
R
I
H
Q
P
A
K
D
W
E
E
Q
---
T
L
P
V
Q
L
I
E
R
F
S
T
A
P
L
K
23
PsiBlast_CBE
73.99
61%
-106
- C1 -
-
4RK0
1
?
B:
[8-274]
------------------------------------------------------------------
K
T
I
G
V
I
V
P
D
I
T
N
P
F
F
A
Q
L
I
R
G
I
E
S
V
L
Y
K
E
N
F
I
L
I
L
C
N
A
D
Q
D
V
T
R
E
H
E
Y
L
T
E
L
I
R
R
S
V
D
G
F
V
I
A
S
S
E
I
S
N
Q
T
I
N
E
T
L
R
-
A
K
K
I
P
F
I
V
L
D
Q
K
K
A
E
-
G
-
F
S
D
A
V
L
T
D
D
Y
R
G
G
Q
L
A
A
K
H
L
Q
E
Q
R
H
E
Q
V
I
V
V
M
P
P
-
H
A
P
-
V
N
I
Q
Q
-
R
L
K
G
F
C
S
---
V
Y
T
---
E
K
-
V
-
Q
L
I
E
T
E
L
S
K
T
G
G
Y
Q
A
V
P
E
I
L
--
K
--
T
E
--
S
T
G
I
F
A
I
N
D
E
I
A
F
G
L
Y
R
G
L
A
E
A
G
K
K
I
P
E
D
Y
S
I
I
G
Y
D
N
V
D
M
C
E
Y
V
S
P
P
L
T
T
I
A
Q
P
V
F
Q
L
G
Q
T
T
A
T
L
L
L
E
R
I
H
Q
P
A
K
D
W
E
E
Q
---
T
L
P
V
Q
L
I
E
R
F
S
T
A
P
L
K
22
PsiBlast_CBE
73.19
61%
-99
- C1 -
-
4RK0
1
?
C:
[7-274]
-----------------------------------------------------------------
S
K
T
I
G
V
I
V
P
D
I
T
N
P
F
F
A
Q
L
I
R
G
I
E
S
V
L
Y
K
E
N
F
I
L
I
L
C
N
A
D
Q
D
V
T
R
E
H
E
Y
L
T
E
L
I
R
R
S
V
D
G
F
V
I
A
S
S
E
I
S
N
Q
T
I
N
E
T
L
R
-
A
K
K
I
P
F
I
V
L
D
Q
K
K
A
E
-
G
-
F
S
D
A
V
L
T
D
D
Y
R
G
G
Q
L
A
A
K
H
L
Q
E
Q
R
H
E
Q
V
I
V
V
M
P
P
-
H
A
P
-
V
N
I
Q
Q
-
R
L
K
G
F
C
S
---
V
Y
T
---
E
K
-
V
-
Q
L
I
E
T
E
L
S
K
T
G
G
Y
Q
A
V
P
E
I
L
--
K
--
T
E
--
S
T
G
I
F
A
I
N
D
E
I
A
F
G
L
Y
R
G
L
A
E
A
G
K
K
I
P
E
D
Y
S
I
I
G
Y
D
N
V
D
M
C
E
Y
V
S
P
P
L
T
T
I
A
Q
P
V
F
Q
L
G
Q
T
T
A
T
L
L
L
E
R
I
H
Q
P
A
K
D
W
E
E
Q
---
T
L
P
V
Q
L
I
E
R
F
S
T
A
P
L
K
114
HHSearch
65.21
33%
-34
- C1 -
-
1JFT
2
PURR_ECOLI
A:
[1-333]
-------
A
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
K
T
-
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
-
A
M
L
E
E
Y
R
H
I
P
M
V
V
M
D
A
G
E
A
K
A
D
-
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
P
G
P
-
L
E
R
-
N
T
G
A
G
-
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
W
I
V
Q
G
-
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
QP
H
R
--
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
D
G
-
36
PsiBlast_CBE
65.13
32%
-39
- C1 -
-
1PNR
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
111
HHSearch
64.88
33%
-56
- C1 -
-
1RZR
2
CCPA_BACME
C:
[1-332]
-----
M
N
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
-
P
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
V
-
E
E
L
K
-
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
-
N
-
Q
I
P
S
V
T
I
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
-
L
E
E
P
I
N
H
A
K
-
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
-
I
V
E
G
-
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
--
E
ED
E
K
--
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
N
K
E
T
V
D
S
S
I
V
---
Q
L
P
H
R
I
E
F
R
Q
S
T
K
---
8
PsiBlast_PDB
64.60
33%
-59
- C1 -
-
1RZR
2
CCPA_BACME
G:
[3-331]
-------
V
T
I
Y
D
V
A
R
E
A
S
V
S
M
A
T
V
S
R
V
V
N
G
N
P
-
N
V
K
P
S
T
R
K
K
V
L
E
T
I
E
R
L
G
Y
R
P
N
A
V
A
R
G
L
A
S
K
K
T
T
T
V
G
V
I
I
P
D
I
S
N
I
F
Y
A
E
L
A
R
G
I
E
D
I
A
T
M
Y
K
Y
N
I
I
L
S
N
S
D
Q
N
Q
D
K
E
L
H
L
L
N
N
M
L
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
T
E
E
H
V
-
E
E
L
K
-
K
S
P
V
P
V
V
L
A
A
S
I
E
S
T
-
N
-
Q
I
P
S
V
T
I
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
G
H
K
N
I
A
F
V
S
G
T
L
E
E
P
-
I
N
H
A
K
-
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
-
S
-
Y
I
V
E
G
D
Y
T
Y
D
S
G
I
E
A
V
E
K
L
L
EE
D
--
E
K
--
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
Q
D
R
G
L
N
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
R
P
Q
L
T
S
V
V
Q
P
M
Y
D
I
G
A
V
A
M
R
L
L
---
T
K
Y
M
N
K
E
T
V
D
S
SIV
Q
L
P
H
R
I
E
F
R
Q
S
T
----
10
PsiBlast_PDB
64.55
32%
-43
- C1 -
-
1BDH
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
11
PsiBlast_PDB
64.34
32%
-41
- C1 -
-
1QP7
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
A
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
33
PsiBlast_CBE
64.13
32%
-40
- C1 -
-
1QPZ
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
32
PsiBlast_CBE
64.01
32%
-43
- C1 -
-
1WET
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
14
PsiBlast_PDB
63.89
32%
-40
- C1 -
-
1JH9
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
R
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
30
PsiBlast_CBE
63.84
32%
-40
- C1 -
-
1JFT
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
A
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
34
PsiBlast_CBE
63.80
32%
-41
- C1 -
-
1QP4
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
38
PsiBlast_CBE
63.78
32%
-40
- C1 -
-
1JFS
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
F
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
35
PsiBlast_CBE
63.78
32%
-38
- C1 -
-
1QP0
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
31
PsiBlast_CBE
63.75
32%
-39
- C1 -
-
1ZAY
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
R
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---
29
PsiBlast_CBE
63.59
32%
-44
- C1 -
-
2PUD
2
PURR_ECOLI
A:
[2-331]
--------
T
I
K
D
V
A
K
R
A
N
V
S
T
T
T
V
S
H
V
I
N
-
K
T
R
F
V
A
E
E
T
R
N
A
V
W
A
A
I
K
E
L
H
Y
S
P
S
A
V
A
R
S
L
K
V
N
H
T
K
S
I
G
L
L
A
T
S
S
E
A
A
Y
F
A
E
I
I
E
A
V
E
K
N
C
F
Q
K
G
Y
T
L
I
L
G
N
A
W
N
N
L
E
K
Q
R
A
Y
L
S
M
M
A
Q
K
R
V
D
G
L
L
V
M
C
S
E
Y
P
E
P
L
L
A
M
L
E
E
-
Y
R
H
I
P
M
V
V
M
D
W
G
E
A
K
-
A
D
F
T
D
A
V
I
D
N
A
F
E
G
G
Y
M
A
G
R
Y
L
I
E
R
G
H
R
E
I
G
V
I
-
P
G
-
P
L
E
-
A
N
T
G
A
G
R
L
A
G
F
M
K
A
M
E
E
A
M
I
K
V
P
E
-
S
-
W
I
V
Q
G
D
F
E
P
E
S
G
Y
R
A
M
Q
Q
I
L
--
S
--
Q
P
HR
P
T
A
V
F
C
G
G
D
I
M
A
M
G
A
L
C
A
A
D
E
M
G
L
R
V
P
Q
D
V
S
L
I
G
Y
D
N
V
R
N
A
R
Y
F
T
P
A
L
T
T
I
H
Q
P
K
D
S
L
G
E
T
A
F
N
M
L
L
D
R
I
V
N
K
R
E
E
P
Q
S
I
---
E
V
H
P
R
L
I
E
R
R
S
V
A
---