@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZP4: (2017-12-16 )
MVIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG
Atome Classification :
(15 SA)
.........10........20........30....-....40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160....---------...170.......180.......190.......200.......210.......220.......230.......240....-----------...250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390--......-----...400.......410.......420.......430--.......440.......450.......460.......470--........480--........490.......500.--......510.---------......520.....-..530.......540.......550.....---..560.......570.-......580-----.......-----..590.......600.......610....--...620.......630.......640.---------------..-.....650.......660.......670.......--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
V
I
I
K
K
K
F
T
V
L
L
T
I
I
V
T
G
I
MSG
F
A
L
V
S
I
N
K
Q
V
L
YR-
T
N
E
F
F
HQTDTYTPIR
L
P
Q
H
FI
G
Q
E
E
Y
E
Q
L
I
M
V
F
E
NVSS
E
T
E
L
S
Y
M
K
K
TVNESNEVDTSW
N
F
K
I
Q
P
K
L
E
M
T
L
Y
Y
QGDVKSSHEKVPYSNT
S
F
R
V
T
SIEE
S
I
K
I
KDFEG
E
F
F
L
M
TR
E
K
E
A
Y
E
R
F
I
S
L
F
T
D
R
F
N
---------
Q
A
F
H
T
D
Y
A
T
N
I
F
E
D
F
ENSY
S
Y
S
V
ISNT
D
V
Y
N
Y
R
V
Y
L
T
I
G
L
I
L
L
F
L
L
L
S
S
F
F
L
L
MNK
E
I
S
L
L
LNNDF
S
L
H
Q
V
L
W
C
L
LGK
K
K
-----------
I
I
I
T
F
I
I
A
G
I
I
G
G
F
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M
Y
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E
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AN
V
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L
A
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FSS
S
Q
L
A
VSHE
P
P
K
E
IAGED
Y
H
V
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Y
P
V
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IGK
N
H
V
D
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I
YSNRFAS
A
A
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Q
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NKN----G
S
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V
N-----
V
S
D
YLNE
E
N
E
Q
FG
R
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I
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L
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Y
L
K
KFPLIDVS
G
R
L
I
--
Q
I
TEKETH
P
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RYRH
T
D
L
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Y
Q
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I
SEK---EP
K
F
L
F
I
KNN---Q
P
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FIPSIPWIEHYP
V
V
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I
L
--TLKN
S
M
Y
L
E
R---------NILSGEIYP
P
L
K
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S
K
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R
L
F
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L
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Q
LRDN
L
Q
L
SFPYT
Q
---
T
E
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S
R
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F
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L
-
I
Q
I
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L
L
T
-------
F
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F
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L
-----
S
Y
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M
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C
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C
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Y
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--
Y
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F
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M
M
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KWGT
T
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L
F
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IER-E---------------
P
K
-
Y
L
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F
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V
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F
I
LSTEKK
S
Q
L
L
L
MNGG--------------------------------------
16
Fugue
88.54
17%
-
- C1 -
-
4R3Z
-
SYRC_HUMAN
B:
[2-660]
D
V
L
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C
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L
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L
---------
K
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P
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N
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L
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Q
A
-
K
F
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Q
C
N
---------
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A
M
G
I
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M
L
K
T
K
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Q
---------
K
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K
H
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G
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V
H
L
R
K
D
F
V
-------------
S
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Q
L
T
S
L
L
V
N
G
V
Q
L
P
A
----
L
G
E
N
K
K
-----------
V
I
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D
F
S
S
P
N
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M
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G
H
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S
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L
F
E
F
A
G
Y
------
D
V
L
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N
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G
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--
I
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Y
Q
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N
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G
F
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Q
V
D
----------
D
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V
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G
C
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Y
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A
A
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Q
R
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--
E
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---
A
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M
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V
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M
I
G
W
Y
D
----
P
--
K
V
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F
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A
G
F
---------
G
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V
L
G
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D
K
K
K
F
K
T
R
-
S
G
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--
T
V
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KVL
T
A
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A
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Y
A
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HNRLNDY
I
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DDRG
N
T
A
A
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L
L
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R
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P
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I
-
L
---------------
Q
K
-
I
L
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D
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L
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T
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Y
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A
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QTGKILKVN
M
W
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M
L
L
C
E
A
V
A
A
V
M
A
K
G
F
D
I
L
G
I
K
P
V
Q
RM
12
Fugue
54.36
18%
20
* C3 *
-
4R1D
-
?
A:
[45-561]
------
Q
T
A
P
L
P
V
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F
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N
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L
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M
D
D
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L
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I
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A
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T
W
A
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P
K
A
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L
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---
A
E
Q
V
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V
D
D
----------------
Q
G
T
I
D
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G
Q
-----
S
G
L
S
------
E
E
A
A
R
L
R
---
G
W
G
K
V
M
---
R
S
A
Y
N
P
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M
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L
M
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R
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IVSRRELQ
A
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A
L
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P
G
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L
L
R
A
S
R
Y
------
Q
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A
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N
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Q
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A
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G
-------
S
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T
I
Y
H
H
M
R
C
G
Y
E
G
I
A
Q
V
-----
V
L
G
---------
R
N
A
G
E
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A
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S
A
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A
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Q
V
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D
-
I
D
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R
A
Y
P
Q
N
Q
D
P
Y
E
E
I
Y
K
N
TTWY
G
L
V
P
E
Q
-----
N
S
Q
Y
L
D
M
S
D
K
K
E
G
L
R
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G
--------------------------------------
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R
D
N
F
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A
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GYH
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Y
A
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A
D
---
D
S
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H
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W
-
R
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L
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N
D
D
E
N
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---------
N
S
W
F
R
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--
T
I
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-
Q
G
P
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G
N
--
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A
S
G
S
G
G
D
E
---
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T
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---
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Q
A
P
A
L
A
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K
A
S
F
R
H
G
--------------------------------------
S
K
G
K
G
Q
A
N
T
K
R
G
Y
E
H
Q
E
S
--
Y
N
D
----
A
R
A
Q
W
A
A
L
Y
G
V
I
K
I
T
Q
L
A
-
D
---------------
W
---------------------------------------------------------------------------
20
Fugue
41.56
31%
-327
* C2 *
-
4XTR
-
?
G:
[15-36]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
W
R
V
Y
L
L
I
V
L
L
V
M
L
L
F
I
F
L
I
M
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
31.14
16%
-240
- C2 -
-
5NIL
-
?
K:
[548-579]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
E
R
T
R
E
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G
I
R
M
A
V
G
A
R
A
S
D
V
L
Q
Q
F
L
I
E
A
V
-----------
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
29.04
21%
-72
- C3 -
-
3AQB
-
HEXA_MICLU
A:
[4-138]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
M
R
Y
L
H
K
I
E
L
E
L
N
R
L
T
S
R
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Y
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F
F
K
K
I
A
F
D
---
A
E
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V
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D
L
N
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C
A
-
I
V
--
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M
Q
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FINEDNKDS
F
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C
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K
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I
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A
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I
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T
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A
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N
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N
K
Q
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H
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M
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I
Q
P
Y
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
22.01
8%
-151
- C2 -
-
5NIL
-
?
K:
[529-647]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
I
S
-------
L
V
V
G
G
I
G
-----
V
M
N
I
M
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C
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G
G
A
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S
L
L
I
A
FTLQLFLPGWEIGFS
P
L
A
L
L
L
A
F
L
C
S
T
V
T
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G
W
L
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A
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P
V
D
A
L
A
R
---------------------------------------
3
HHSearch
19.63
7%
-94
- C2 -
-
2JNA
-
?
A:
[52-80]
------------------------------------------------------------
S
P
S
D
L
R
E
K
L
S
E
L
A
D
A
K
G
G
K
Y
Y
H
I
I
A
A
R
E
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
17.27
26%
-26
- C2 -
-
5TOH
-
VP35_MABVM
A:
[1-52]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
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I
W
D
Q
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H
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R
Q
---
L
H
E
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P
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
17.20
19%
-113
- C3 -
-
1BL1
-
?
?:
[1-31]
------------------------------------------------------------------------------------------------------------------------------------------
S
E
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E
T
R
E
R
E
V
F
D
R
L
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M
I
Y
T
V
G
Y
S
---------
V
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
15.87
20%
-91
- C2 -
-
2LN3
-
?
A:
[40-64]
------------------------------------------------------------
E
I
E
E
F
E
R
D
M
E
D
L
A
K
K
T
G
V
Q
I
Q
K
Q
W
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
15.76
10%
-219
- C2 -
-
5X5Y
-
?
F:
[75-127]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
G
R
L
Y
L
E
S
E
M
T
V
L
S
A
T
G
M
S
Q
K
R
L
--
L
G
Y
T
M
A
P
A
L
L
V
A
I
L
V
A
W
L
----------------------------------------------------------------------------------------------------
7
HHSearch
14.07
11%
4
- C2 -
-
2L69
-
?
A:
[34-60]
------------------------------------------------------------
S
P
Q
E
L
K
D
S
I
E
E
L
V
K
K
Y
N
A
T
I
V
V
V
V
V
D
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
12.64
12%
-52
- C2 -
-
4PWW
2
?
A:
[54-78]
-------------------------------------------------------------
R
K
E
L
A
K
E
A
E
R
L
A
K
E
F
G
I
T
V
T
R
T
I
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
11.03
7%
42
- C2 -
-
1EF5
-
RGL1_MOUSE
A:
[664-690]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
K
S
I
M
L
T
-
S
Q
D
K
T
P
A
V
I
Q
R
A
M
S
K
H
N
L
E
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
4.97
24%
-
- C2 -
-
2MXB
-
A:
[25-49]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
S
L
L
L
T
V
L
A
L
L
S
H
R
R
T
L
Q
Q
K
I
W
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------