@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZX2: (2017-12-17 )
MMRTMLISLSVGVYMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTINHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQVSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTTNTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVTKSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTVITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDWMQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNEKINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARISRKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETKKKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDADDWF
Atome Classification :
(20 SA)
-----------.........10........20........30........40........50.......--.60........70........80........90----........100.......110.......120.......130...---....-----140-------..-.......150.......160.......170.......180.......190.......200....-...210.......220.-......230.....--..240.......250.......260......--------.270.......280.-..-.--...290.......300.......310.......320..------.....330...---....340....----.----..350---..-------....--.360.......370---...------------......380-----....------------------....390.......--------400----........410.......420.......430.....-..--440.........450........460.....---..470....----...480.......490........500.......510......------------------.520..--------------.....530.......540........--550.......560.......570.......580.......590........600.......610........620.......630.......640.......650...--------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------M
M
R
T
M
L
I
S
L
S
V
G
V
Y
M
H
VPVQAT
T
Q
T
I
K
V
V
R
T
SVSETTDS
P
I
T
I
T
H
T
FTDANG
K
Q
L
L
P
A
--
L
TSYNKVSYPPTI
N
H
Y
W
LIPNK
T
L
WTSETGSSV----
P
L
S
I
F
SDMTDPTK
G
D
Q
L
K
Q
I
T
D
I
L
N
H
A
L
T
D
IKDGGS
A
Q
V
S
Y
V
YE---K
D
Y
S
-----
Q
---------
F
E
-
R
K
K
I
D
V
LAGTKV
S
I
S
D
L
V
E
R
L
KNADGTQ
G
D
M
S
K
V
ISNNG
N
I
V
D
TTNTG
T
S
T
I
S
L
S
YFDP
I
A
L
K
T
-
M
T
A
S
A
V
I
H
V
RADQTAIK-GK
D
L
H
L
RTGESY
A
P
--
K
D
L
V
E
Y
V
T
KSDGTSG
N
K
E
E
I
K
MNGTVDTTTP--------GEY
P
V
V
L
T
Y
IDSKTS-NV-A--
E
T
T
A
V
V
Y
V
EASAAS
S
T
V
I
T
H
FIDSQTNK
E
L
Q
A
E
T
H
M
S
S
------
V
NRIPDLRLP
A
---
E
F
SDRVPNIDL----
S
----
T
YEQN---GK-------V
T
S
I
--
S
D
W
M
Q
ANGLD
R
K
-----
S
H
W
------------
S
E
I
L
E
V
L
H
------
S
E
L
M
------------------
N
N
RKQSGG
E
I
T
F
T
Y
--------
V
Y
-----IPDNRSLEG
H
D
L
I
VHPNEKI
N
K
E
E
L
I
Q
S
A
T
N
SLGKP-VP--L--
K
D
V
S
V
T
I
NEVP-LEDG
Y
L
TKQTG
D
F
T
I
M
---
Y
SYHDP
Y
S
L
----
Q
E
L
H
A
Q
S
L
L
H
VLPLN-KQI
D
Q
K
E
Q
K
R
Q
E
E
S
L
S
E
K
K
Q
Q
M
A
HAVS------------------PTGK
V
K
--------------
Q
TR
S
L
E
L
A
R
I
S
R
K
I
S
ES-
N
K
T
I
R
Q
E
A--HLAPQVSGLENEILE
P
K
I
K
Q
Q
S
E
K
E
F
V
A
KQSEDQKES
D
D
Q
K
E
-
T
K
K
K
R
LSTIDSTDEHLQPQ-VPLPSPGTPAPGGGI
P
S
S
A
L
G
D
F
M
R
GMAG
T
W
V
Y
ANRNEFDADDWF--------------
28
Fugue
62.73
15%
51
- C3 -
-
2QZV
-
MVP_RAT
A:
[3-779]
GCGCPCGCGAM
A
T
E
E
A
I
I
R
I
P
P
Y
H
Y
I
H
V
L
D
Q
N
S
N
V
S
R
V
E
V
G
P
K
T
Y
I
R
Q
D
N
E
---
R
V
L
F
A
P
V
R
M
V
T
V
P
P
R
HY
C
I
V
A
N
P
V
S
R
D
T
Q
S
S
V
L
F
D
I
T
G
Q
V
R
L
R
H
A
D
Q
E
I
R
L
A
Q
D
P
F
P
L
Y
P
Q
V
V
L
P
N
T
A
L
H
L
K
A
L
L
D
F
E
D
K
N
G
D
K
V
M
A
G
D
E
----
W
L
F
E
G
P
G
T
Y
I
P
-----
Q
---------
K
E
-
V
E
V
V
E
I
I
Q
A
T
V
I
K
Q
N
Q
A
L
R
L
R
A
R
K
E
C
F
D
R
E
G
K
G
R
V
T
G
E
E
W
L
V
R
S
V
G
A
Y
L
P
A
V
F
E
E
V
L
D
L
V
D
A
V
I
-
L
T
E
K
T
A
L
H
L
R
A
L
Q
N
F
R
D
-
L
R
G
V
L
H
R
T
G
E
E
W
L
V
--
T
V
------
Q
D
T
E
A
H
V
P
D
V
Y
E
E
V
L
G
V
V
P
I
T
T
L
--------
K
S
F
F
L
Q
----
P
G
E
R
L
-
E
R
-
G
--
I
Q
D
V
Y
V
L
S
E
Q
Q
G
L
L
L
K
A
L
Q
P
L
E
E
G
E
S
E
E
K
V
S
H
Q
A
G
D
C
W
------
L
I
R
G
P
L
E
Y
V
P
S
A
K
V
E
V
V
E
E
R
Q
A
I
P
L
----
D
Q
N
E
G
I
Y
V
Q
D
VKT
G
K
-------
V
R
A
V
I
G
S
T
Y
M
L
T
Q
D
E
V
L
W
E
K
ELP
S
G
V
------------
E
E
L
L
N
L
G
H
------
D
P
L
A
D
R
G
QKGTAK
P
L
Q
P
SAPR
N
K
T
R
V
V
S
Y
R
V
P
H
N
A
A
--------
V
Q
-----
V
Y
D
Y
R
A
K
R
A
R
V
V
F
G
P
E
L
V
T
L
D
P
E
E
Q
F
T
V
L
S
L
S
A
G
R
P
K
R
P
--
H
--
A
R
R
A
L
C
L
L
L
G
P
D
F
F
T
D
V
I
T
I
E
T
A
D
H
A
R
L
Q
LQ
L
A
Y
N
W
H
F
E
L
K
N
R
N
D
P
A
E
A
A
K
L
F
S
V
P
D
F
V
-
G
D
A
C
K
A
I
A
S
R
V
R
G
A
V
A
S
V
T
F
D
D
F
H
K
N
S
A
R
I
I
R
M
AVFGFEM
S
E
D
T
G
P
D
G
T
L
L
PKARD
Q
A
V
F
PQNG
L
V
V
S
S
V
D
V
Q
S
V
E
P
V
D
Q
R
T
-
R
D
A
L
Q
R
S
V
--
Q
L
A
I
E
I
T
T
N
S
Q
E
A
A
A
K
H
E
A
Q
R
L
E
Q
E
A
R
G
R
L
E
R
Q
K
I
L
D
Q
S
E
A
E
-
K
A
R
K
E
L
L
E
L
E
A
M
S
M
A
V
E
S
T
G
N
A
K
A
E
A
E
S
R
A
E
A
A
R
I
E
G
E
G
S
V
L
Q
A
K
L
K
A
Q
A
L
A
I
E
T
E
A
E
L
E
R
V
K
K
V
R
E
MELIYAR
A
Q
L
E
L
16
HHSearch
58.07
22%
-87
- C4 -
-
5FQ8
-
?
G:
[23-90]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
I
V
L
E
K
G
Q
P
F
-
V
--
E
P
G
Y
Y
A
E
M
N
G
-
E
D
I
--
T
E
S
V
Q
I
K
G
S
V
D
V
N
T
P
--------
G
I
Y
N
L
V
Y
A
A
Y
N
E
D
G
F
--
A
-
K
--
T
F
T
R
T
V
Y
V
A
D
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
55.15
20%
1
- C4 -
-
4HME
-
?
A:
[337-480]
------------------------------------------------------------------------------------------------
R
V
E
L
D
S
H
F
----
D
P
L
I
G
I
T
A
K
D
Y
Q
G
N
D
I
T
A
D
V
T
---
V
S
G
S
V
N
T
N
Q
V
G
D
Y
L
L
T
Y
S
V
S
S
--
D
D
E
T
T
N
Q
P
R
K
I
T
V
Y
E
I
L
P
A
F
T
G
I
T
D
T
T
V
V
I
D
S
E
F
D
---
P
M
Q
G
V
S
A
S
H
P
T
Q
G
D
L
T
A
N
I
T
V
T
G
-
E
V
D
T
N
V
V
G
V
Y
E
L
T
Y
Q
L
F
Y
G
Q
D
N
Q
Q
N
M
T
D
K
R
I
V
T
V
V
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
54.82
16%
-15
- C4 -
-
4MB4
1
?
A:
[335-480]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
R
V
E
L
D
S
H
F
D
---
P
L
I
G
I
T
A
K
D
Y
Q
G
N
D
I
T
A
D
V
T
V
S
-
G
S
V
N
T
N
Q
V
G
D
Y
L
L
T
Y
S
V
S
S
D
D
E
-
T
--
T
N
Q
P
R
K
I
T
V
Y
E
I
L
P
A
F
T
G
I
T
D
T
T
V
V
I
D
S
E
F
D
P
--
M
Q
G
V
S
A
S
H
P
T
Q
G
D
L
--
T
A
N
I
T
V
T
G
E
V
D
T
N
V
V
--------
G
V
Y
E
L
T
Y
Q
L
F
Y
G
Q
D
N
--
Q
-
Q
N
M
T
D
K
R
I
V
T
V
V
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
54.63
20%
-6
- C4 -
-
4MB4
1
?
A:
[337-480]
------------------------------------------------------------------------------------------------
R
V
E
L
D
S
H
F
----
D
P
L
I
G
I
T
A
K
D
Y
Q
G
N
D
I
T
A
D
V
T
---
V
S
G
S
V
N
T
N
Q
V
G
D
Y
L
L
T
Y
S
V
S
S
--
D
D
E
T
T
N
Q
P
R
K
I
T
V
Y
E
I
L
P
A
F
T
G
I
T
D
T
T
V
V
I
D
S
E
F
D
---
P
M
Q
G
V
S
A
S
H
P
T
Q
G
D
L
T
A
N
I
T
V
T
G
-
E
V
D
T
N
V
V
G
V
Y
E
L
T
Y
Q
L
F
Y
G
Q
D
N
Q
Q
N
M
T
D
K
R
I
V
T
V
V
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
53.62
16%
-14
- C4 -
-
4HME
-
?
A:
[335-480]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
R
V
E
L
D
S
H
F
D
---
P
L
I
G
I
T
A
K
D
Y
Q
G
N
D
I
T
A
D
V
T
V
S
-
G
S
V
N
T
N
Q
V
G
D
Y
L
L
T
Y
S
V
S
S
D
D
E
-
T
--
T
N
Q
P
R
K
I
T
V
Y
E
I
L
P
A
F
T
G
I
T
D
T
T
V
V
I
D
S
E
F
D
P
--
M
Q
G
V
S
A
S
H
P
T
Q
G
D
L
--
T
A
N
I
T
V
T
G
E
V
D
T
N
V
V
--------
G
V
Y
E
L
T
Y
Q
L
F
Y
G
Q
D
N
--
Q
-
Q
N
M
T
D
K
R
I
V
T
V
V
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
53.27
33%
-44
- C4 -
-
2KPN
-
?
A:
[20-86]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
H
V
G
D
S
F
V
P
--
M
A
E
V
L
A
I
D
K
E
D
G
D
L
--
T
S
K
I
K
V
D
G
E
V
D
T
T
K
A
--------
G
T
Y
V
L
T
Y
T
V
T
D
S
K
G
H
--
E
-
V
--
T
A
K
Q
T
V
T
V
K
V
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
53.14
38%
-31
- C4 -
-
2KPN
-
?
A:
[18-85]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
T
I
H
V
--
G
D
S
F
V
P
--
M
A
E
V
L
A
I
D
K
E
D
G
D
L
T
S
K
--
I
K
V
D
G
E
V
D
T
T
K
A
--------
G
T
Y
V
L
T
Y
T
V
T
D
S
K
G
H
-
E
V
T
A
--
K
Q
T
V
T
V
K
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.85
22%
21
- C2 -
-
3JB7
1
?
B:
[276-490]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
L
G
L
D
V
G
D
D
Y
L
K
E
Y
K
K
L
L
F
Y
G
V
I
T
D
A
I
P
S
G
---
I
S
A
R
S
T
I
M
K
I
S
P
H
K
M
M
N
P
S
G
G
A
L
A
V
L
S
K
F
L
E
A
V
V
S
T
N
V
-
I
--
N
A
T
L
V
V
Y
A
E
K
G
A
G
K
T
S
F
L
S
T
Y
A
E
Q
L
S
L
A
S
G
Q
V
V
G
H
L
S
S
D
A
Y
G
R
W
L
A
K
N
K
D
V
E
E
P
S
---
F
A
Y
D
Y
V
L
S
L
D
T
DDNE
S
----
Y
Y
E
Q
K
---
A
S
E
L
L
I
S
H
G
I
S
E
V
--
A
Q
Y
E
L
L
S
V
R
K
K
I
-----
K
M
M
------------
D
E
M
N
E
V
L
I
------
A
Q
L
E
------------------
N
A
D
T
H
S
--
E
R
N
F
Y
Y
--------
M
V
S
T
GKT
T
P
R
T
L
I
V
E
G
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
45.98
13%
-86
- C4 -
-
5FQ8
-
?
G:
[24-90]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
V
L
E
K
G
Q
P
F
----
V
E
P
G
Y
Y
A
E
M
N
G
-
E
D
I
T
E
S
V
Q
I
K
-
G
S
V
D
V
N
T
P
G
I
Y
N
L
V
Y
A
A
Y
N
E
D
G
F
A
--
K
T
F
T
R
T
V
Y
V
A
D
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.89
22%
24
* C2 *
-
3JB6
1
?
B:
[276-490]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
L
G
L
D
V
G
D
D
Y
L
K
E
Y
K
K
L
L
F
Y
G
V
I
T
D
A
I
P
S
G
---
I
S
A
R
S
T
I
M
K
I
S
P
H
K
M
M
N
P
S
G
G
A
L
A
V
L
S
K
F
L
E
A
V
V
S
T
N
V
-
I
--
N
A
T
L
V
V
Y
A
E
K
G
A
G
K
T
S
F
L
S
T
Y
A
E
Q
L
S
L
A
S
G
Q
V
V
G
H
L
S
S
D
A
Y
G
R
W
L
A
K
N
K
D
V
E
E
P
S
---
F
A
Y
D
Y
V
L
S
L
D
T
DDNE
S
----
Y
Y
E
Q
K
---
A
S
E
L
L
I
S
H
G
I
S
E
V
--
A
Q
Y
E
L
L
S
V
R
K
K
I
-----
K
M
M
------------
D
E
M
N
E
V
L
I
------
A
Q
L
E
------------------
N
A
D
T
H
S
--
E
R
N
F
Y
Y
--------
M
V
S
T
GKT
T
P
R
T
L
I
V
E
G
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
44.79
15%
-107
- C4 -
-
2KPN
-
?
A:
[52-90]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
D
T
T
K
A
G
T
Y
V
L
T
---
Y
T
V
T
D
S
K
G
H
----
E
V
T
-
A
K
Q
T
V
T
V
K
V
R
E
-
E
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
39.28
8%
9
- C3 -
-
3OKQ
-
BUD6_YEAST
A:
[553-677]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
N
R
M
Y
M
E
K
S
Q
T
E
-
L
G
D
L
S
D
T
L
L
S
K
V
D
D
L
Q
D
V
I
E
I
M
R
K
D
V
A
------------------
E
R
R
S
----------------
Q
P
A
K
K
K
L
E
T
V
S
K
D
L
E
N
A
-
Q
A
D
V
L
K
L
Q
--
E
F
I
D
T
E
K
P
H
W
K
K
T
W
E
A
E
L
D
K
V
C
E
E
Q
Q
F
L
T
L
Q
E
E
L
I
L
D
L
K
E
D
L
-
G
K
A
L
E
T
F
D
L
I
K
L
C
C
-----------------------------------------------------------------
5
PsiBlast_PDB
38.15
24%
21
- C2 -
-
5H0R
-
?
G:
[327-490]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
L
A
V
L
S
K
Y
I
E
A
V
V
S
T
N
V
-
I
--
N
A
T
L
V
V
Y
A
E
K
G
A
G
K
T
S
F
L
S
T
Y
A
Q
Q
L
S
L
A
S
G
Q
I
V
G
H
L
S
S
DAYGRW
L
A
K
N
K
D
V
E
E
P
S
---
F
E
Y
D
Y
V
L
S
L
D
T
DDNE
S
----
Y
Y
E
Q
K
---
A
--------------
S
E
L
L
T
S
H
G
I
S
E
L
-----
S
Q
Y
ELLSVRRKVKMM
N
E
M
D
E
I
L
I
------
A
Q
L
D
------------------
N
A
N
T
H
S
--
E
R
N
F
Y
Y
--------
M
V
STGKN
T
P
R
T
L
I
V
E
G
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.76
20%
28
- C3 -
-
4ZM1
-
WZZB_SHIFL
A:
[62-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
E
E
P
E
K
L
T
I
E
P
S
V
K
N
Q
Q
L
P
L
T
V
S
------------------
Y
V
G
Q
T
A
--------------
E
G
A
Q
M
K
L
A
Q
Y
I
Q
Q
V
D
D
K
V
N
Q
E
L
E
K
D
L
K
D
N
I
A
L
G
R
K
N
L
Q
D
S
L
R
T
Q
E
V
V
A
Q
E
Q
K
D
L
R
I
R
Q
I
Q
E
A
L
Q
Y
A
N
Q
A
Q
V
T
K
P
Q
V
Q
Q
T
E
D
V
T
Q
D
T
L
---------------------------------------------------------------
23
HHSearch
35.10
15%
-95
- C4 -
-
5JMB
-
?
B:
[55-88]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
M
P
F
E
--------
G
K
Y
E
V
T
F
G
V
Q
T
R
G
G
--
I
V
-
Y
--
G
N
P
A
T
F
T
I
D
S
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
34.57
34%
-53
- C1 -
-
4HU8
1
?
A:
[144-186]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
L
T
------------------
N
N
R
N
E
T
T
G
E
I
T
Y
T
F
S
T
A
D
R
M
V
N
A
A
-----
I
A
E
G
L
K
I
H
G
H
T
L
L
W
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
33.68
14%
85
- C3 -
-
4WIK
-
SFPQ_HUMAN
A:
[370-597]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
A
L
S
V
R
N
LSPYVS
N
E
L
L
------------------
E
E
A
F
S
Q
F
G
P
I
E
R
A
V
--------
V
I
-----
V
D
D
R
G
R
S
T
G
K
G
I
V
E
F
A
S
K
P
A
A
R
K
A
F
E
R
C
S
E
G
V
F
L
L
T
-
T
T
--
P
--
R
P
V
I
V
E
P
L
E
Q
L
-
D
D
E
D
G
L
P
E
K
L
A
Q
K
N
P
M
---
Y
Q
K
E
R
E
T
P
P
----
R
F
A
Q
H
G
T
F
E
Y
E
Y
S
Q
R
W
K
S
L
D
E
M
E
K
Q
Q
R
E
Q
V
E
K
N
M
K
D
A
K
D
K
L
E
S
------------------
E
M
E
D
A
Y
--------------
H
E
H
Q
A
N
L
L
R
Q
D
L
M
R
R
Q
E
-
E
L
R
R
M
E
E
L
--
H
N
Q
E
M
Q
K
R
K
E
M
Q
L
R
Q
E
E
E
R
R
R
R
E
E
E
M
M
I
R
Q
R
E
M
E
E
Q
M
R
R
Q
R
E
-
E
S
Y
----------------------------------------------------------------------------
25
HHSearch
33.51
17%
38
- C4 -
-
2L7Y
-
?
A:
[18-84]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
V
G
D
S
L
D
L
S
E
G
R
F
A
V
A
Y
S
N
D
T
M
-
E
E
H
S
F
TD
E
G
V
E
I
---------
S
G
Y
D
A
Q
K
T
G
R
Q
T
L
T
---
L
H
Y
Q
G
H
---------
E
-
V
S
F
D
V
L
V
S
P
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
28.04
11%
100
- C3 -
-
2PMS
-
?
C:
[1-125]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
S
H
M
D
A
E
E
V
A
P
Q
A
K
I
A
E
L
E
N
Q
V
H
R
L
E
Q
E
------------------
L
K
E
I
D
E
--------------
A
P
L
Q
S
K
L
D
A
K
K
A
K
L
S
K
L
-
E
E
L
S
D
K
I
D
--
E
L
D
A
E
I
A
K
L
E
D
Q
L
K
A
A
E
E
E
D
Y
F
K
E
G
L
E
K
T
I
A
A
K
K
A
E
L
E
K
T
E
A
-
D
L
K
K
A
V
N
E
-----------------------------------------------------------------------