@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U2V7: (2017-12-23 )
MQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------........---.10........20..---......30....--------....40........50.....-------...60--.......----------------.70......--..80-----....---.....90......-------.---.100..------------......110...------..---.----------.-120.......130..-------.----..-------..140-------.------.......150-...----------.--------...160.-.---....---.170.......---------------180-----------.........190.------------------.......200....--...210.......220..-.....--230....------...240------.......250...----....--260.......270.......280.....-----..290--.......300------------..--------.....---------310--------------........---.320.......330..-----.....340..-----..--...350.......360...---------....370-...--.....380..---------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTLVTKG---
D
L
N
E
L
F
R
S
H
L
E
K
A
I
N
---
T
L
L
R
T
E
L
T
A
F
L
D
--------
Y
E
KYDRTGFNSGNSRN
G
S
Y
F
R
-------
S
I
K
TE--YG
E
L
T
L
E----------------IPRDRNGE
F
--
K
Q
Q------TLPA---YKRTND
T
L
E
T
T
I
I
-------
H
---
L
F
E-KG------------V
T
M
S
E
I
A
D
L
I
E
K
------
M
Y---G----------H-HYT
P
Q
T
M
S
N
M
T
K
V
L
T
-------
E
----
E
V
-------
N
A
F
K
--------
S
------RALND
K
Y
V
A
I
-
F
M
D----------A--------
T
Y
IPLKR-Q---TVSK---E
A
I
Y
I
A
I
G
IRE---------------D-------------
G
T
K
E
V
L
S
Y
AIA-P------------------TE
S
T
Y
V
W
N
E
L
L
Q
D
I
--
N
SR
G
V
Q
E
V
L
L
F
I
TDGL
K
G
-
M
K
D
T
I
--
H
Q
IYPKA------KY
Q
H
C
C
------
I
HVSRNI
A
H
K
V
RV----K
D
R
K
--
E
I
C
D
D
F
K
A
V
Y
QANS
K
E
E
A
N
T
F
L
S
G
M
I
E
K
-----
W
K
KNY--
P
K
V
T
Q
S
L
IEN------------QD--------
L
L
T
F
Y---------D----------------F
P
P
S
I
R
R
T
---
I
Y
S
T
N
L
I
E
S
F
N
K
Q
I
K
R
-----
Y
S
R
R
K
E
Q
FQ
N
-----
E
E
--
S
L
E
R
F
L
V
S
I
F
D
T
Y
N
Q
K
F
L
N
---------RSHK
G
F
--
Q
Q
V
--
T
D
T
L
V
S
M
FTE---------------------------------------------------------------------------------------------------------------
46
Fugue
76.55
15%
-
- C2 -
-
5DSE
-
TTC7B_HUMAN
A:
[140-843]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V
I
A
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A
Y
A
T
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C
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ED
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N
---
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---
G
M
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DPFCPQE
N
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A
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L
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M
A
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-------------
V
V
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--
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---
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L
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--------
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------
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V
V
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Y
L
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L
--------
G
L
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A
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A
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---
L
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G
M
Q
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V
L
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---------------
A
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L
L
A
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L
S
-
P
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A
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L
A
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L
-
Q
G
D
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H
L
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Y
H
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------
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N
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I
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M
A
L
S
E
Y
P
-----
E
N
F
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--
L
L
F
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K
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L
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P
D
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L
L
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K
H
M
L
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I
-----
W
K
S
C
Y
LH
P
W
M
T
L
A
Q
I
W
L
------------
H
A
--------
A
E
V
Y
I
---------
G
I
GK
P
A
E
A
T
A
C
T
Q
E
A
A
N
L
F
P
M
S
H
N
V
---
L
Y
M
R
G
Q
I
A
E
L
R
G
S
M
D
E
-----
A
R
R
W
Y
E
E
A
L
A
I
SPTH
V
K
--
S
M
Q
R
L
A
L
I
L
H
Q
L
G
R
Y
S
L
A
E
---------
K
I
L
R
D
A
--
V
Q
V
--
N
S
T
A
H
E
V
W
N
G
L
G
E
V
L
Q
A
Q
GN
D
A
A
A
T
E
C
F
L
T
A
L
E
L
E
A
S
SPAVPFTIIPRVL-----------------------------------------------------------------------
53
Fugue
58.35
18%
23
- C2 -
-
5SVD
-
NOP9_YEAST
A:
[5-589]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
M
F
F
G
---
V
L
D
R
E
E
L
E
Y
F
K
Q
A
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S
---
T
L
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A
F
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A
P
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--------
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I
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K
E
L
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L
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-------
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R
V
I
L
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----------------
C
D
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L
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D
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--
F
Q
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F
NGV
F
F
G
L
S
C
---
H
K
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A
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T
L
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V
-------
R
S
A
A
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-
R
E
L
L
TYVT
M
E
N
M
F
L
F
M
L
N
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L
K
P
H
L
K
T
------
M
M
---
N
----------
H
-
Q
Y
A
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R
L
L
I
L
I
L
S
-------
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----
K
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LPV
Y
Q
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P
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F
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--------
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----
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D
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T
L
Y
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G
-
F
T
N
GAESRSDIS
Q
S
--------
T
I
T
K
F
R
E
-
Y
---
S
V
D
K
VA
S
P
V
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Q
L
I
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IF-------------
D
-------------
R
D
R
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F
W
R
L
V
F
N
T
A
------------------
D
E
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D
P
K
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L
L
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Y
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--
Y
R
L
Y
M
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D
------
R
I
V
K
L
A
K
RDTT
G
A
F
V
V
R
A
L
L
E
H
L
K
E
----
K
D
V
K
--
Q
I
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A
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V
P
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L
S
M
L
L
N
S
N
-
M
D
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G
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A
I
I
N
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-----
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K
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--
G
Y
L
R
D
D
V
I
A
--------------
Q
--------
L
I
Q
K
Y
---------
Y
----------------
P
E
K
S
D
A
K
N
---
I
L
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C
L
L
--
L
S
A
S
T
L
G
-----
N
T
R
D
D
W
P
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A
E
-----
E
R
--
R
R
S
V
F
L
E
Q
L
I
D
-
Y
D
D
K
F
L
N
---------
I
T
I
D
S
M
--
L
A
L
P-
E
E
R
L
I
Q
M
C
Y
H
GV
F
S
H
V
V
E
H
V
LQTTRVD
I
I
K
R
K
M
L
L
N
I
L
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K
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S
V
N
L
A
C
N
V
Y
G
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H
I
M
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T
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K
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A
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A
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V
RK
M
W
D
W
K
K
L
I
K
E
Q
E
F
E
I
F
P
51
Fugue
51.11
13%
14
- C2 -
-
1IR6
-
RECJ_THET8
A:
[10-394]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
A
L
L
P
L
K
---
G
L
R
E
A
A
A
L
L
E
E
A
L
R
Q
------
G
K
R
I
R
V
H
G
D
--------
Y
D
-------
A
D
G
L
T
G
T
A
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R
-------
G
L
A
A
L
--
G
A
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V
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P
F
----------------
I
P
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L
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E
G
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GV
L
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------
R
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P
E
---
H
L
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-----
A
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D
L
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-------
L
---
T
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D
-
C
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------------
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V
E
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T
---
D
----------
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H
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-------
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----
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L
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----------
A
--------
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P
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P
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---
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A
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A
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---------------
D
-------------
V
A
P
--------------------------------------
L
W
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--
N
R
A
L
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K
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G
L
A
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---
A
S
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S
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--
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A
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T
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A
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A
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I
A
P
R
I
N
A
----
A
S
R
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G
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A
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A
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L
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A
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A
Q
A
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V
G
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L
H
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L
-----
N
A
R
R
Q
--
T
L
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A
M
L
R
K
L
------------
L
P
QADPEAK
A
I
V
L
L
D
---------
P
----------------
E
G
H
P
G
V
M
G
---
I
V
A
S
R
I
L
E
A
T
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F
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-----
V
A
Q
G
K
G
T
V
R
S
-----
L
A
PI
S
A
V
E
A
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S
A
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D
L
L
L
R
Y
G
G
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---------
K
E
A
A
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A
M
D
--
E
A
L
F
P
A
F
K
A
R
V
E
A
Y
A
ARFPDPVREVALLDL-------------------------------------------------------------------------------------------
45
Fugue
49.86
11%
20
- C2 -
-
5L3X
-
NELFD_HUMAN
B:
[1-405]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G
E
I
T
S
V
S
T
A
C
---
Q
Q
L
E
V
F
S
R
V
L
R
T
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---
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I
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G
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----
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--------
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L
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N
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M
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L
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----------------
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Q
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A
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-------
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-
T
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------------
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P
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A
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A
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A
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L
---
S
----------
K
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A
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P
A
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Q
----------
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--------
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F
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A
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I
---
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H
---
K
H
K
Y
I
H
I
L
A
Y
A
---------------
A
-------------
S
V
V
E
T
W
------
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------------------
K
N
K
R
V
S
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N
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--
T
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N
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C
C
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N
A
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T
L
Y
Q
C
I
------
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F
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V
A
------
M
G
V
L
K
W
V
D
W
T
V
S
E
----
P
R
Y
F
--
Q
L
------------
Q
P
V
H
L
A
L
L
D
E
I
S
T
C
-----
H
Q
L
L
H
--
P
Q
V
L
Q
L
L
V
K
L
F
E
TEHSA-----
L
D
--------
V
M
E
Q
L
---------
E
----------------
L
K
K
T
L
L
D
R
---
M
V
H
L
L
S
R
G
Y
V
L
P
V
V
S
Y
-----
I
R
K
C
L
E
K
D
T
D
-----
I
S
--
L
I
R
Y
F
V
T
E
V
L
D
V
I
A
P
P
Y
T
S
---------
D
F
V
Q
L
F
--
L
P
I
L
E
N
D
S
I
A
D
P
V
T
E
F
I
A
H
C
K
S
N
F
I
M
V
N--------------------------------------------------------------------------------------------------
25
HHSearch
49.75
16%
-283
- C- -
-
1K78
-
PAX5_HUMAN
A:
[31-73]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
P
D
V
V
R
Q
R
I
V
-------
E
---
L
A
H
-
Q
G
------------
V
R
P
C
D
I
S
R
Q
L
R
--------------------------
V
S
H
G
C
V
S
K
I
L
G
R
Y
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
46.68
15%
-13
- C1 -
-
4YDD
8
?
B:
[5-333]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
A
P
R
R
Q
-------
L
T
Y
V
T
D
L
N
K
C
I
G
---
C
Q
---------
T
--------
C
T
V
A
C
K
K
L
W
T
T
G
P
G
Q
D
F
M
Y
W
R
-------
N
V
E
T
A
--
P
G
L
G
Y
P
R
----------------
N
W
Q
T
K
G
G
G
Y
--
K
N
G
------
E
L
Q
K
---
G
K
I
P
P
-------
M
-------
I
---
D
Y
G
-
I
P
------------
F
E
F
D
Y
A
G
R
L
F
E
G
------
K
P
---
G
----------
R
-
V
R
P
S
P
T
P
R
S
A
P
N
-
W
D
-------
E
----
D
Q
-------
G
A
G
E
--------
Y
------
P
N
N
S
F
F
Y
L
P
R
-
M
C
N
----------
H
--------
C
T
K
P
A
C
L
-
E
---
A
C
P
N
---
E
A
I
Y
K
R
---
E
Q
---------------
D
-------------
G
I
V
V
I
-------------------------------------
H
Q
D
--
K
C
K
G
A
Q
A
C
V
Q
S
C
P
----------------
Y
A
K
P
------
Y
F
N
P
L
T
------
N
K
A
N
K
C
I
G
C
F
P
R
I
----
E
Q
G
V
--
A
P
A
C
V
A
Q
C
V
G
R
A
M
H
V
G
F
V
D
D
V
N
S
S
V
Y
K
L
-----
I
K
Q
Y
K
--
V
A
L
P
L
H
P
E
F
G
------------
T
E
--------
P
N
V
F
Y
---------
V
-----------------
P
P
V
L
G
P
R
---
I
E
M
A
N
G
E
P
S
T
D
P
K
I
P
L
-----
A
Q
L
E
G
L
F
G
K
Q
-----
V
R
--
D
V
L
A
I
L
Q
S
E
R
E
K
K
M
K
G
L
A
S
---------
D
L
M
D
V
L
I
G
R
R
S
--
T
D
M
M
I
S
P
L
T
----------------------------------------------------------------------------------------------------------------
22
HHSearch
46.04
14%
-253
- C3 -
-
6PAX
-
PAX6_HUMAN
A:
[16-58]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
P
D
S
T
R
Q
R
I
V
-------
E
---
L
A
H
-
S
G
------------
A
R
P
C
D
I
S
R
I
L
Q
--------------------------
V
S
N
G
C
V
S
K
I
L
G
R
Y
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
45.44
9%
-277
- C3 -
-
1PDN
2
PRD_DROME
C:
[16-58]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
P
N
N
I
R
L
K
I
V
-------
E
---
M
A
A
-
D
G
------------
I
R
P
C
V
I
S
R
Q
L
R
--------------------------
V
S
H
G
C
V
S
K
I
L
N
R
Y
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
42.72
12%
14
- C2 -
-
4F52
-
GLMN_HUMAN
E:
[3-585]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
A
V
E
E
L
Q
S
I
I
K
R
C
QILEG
L
F
Q
L
A
G
Q
R
C
I
E
E
G
HT
D
Q
L
L
E
I
I
Q
N
E
K
N
K
V
I
I
---
K
N
M
G
W
N
L
V
G
P
V
V
--------
R
C
L
L
C
K
D
K
E
D
S
K
R
K
V
Y
F
L
I
F
D
-------
L
L
V
K
L
CN
P
K
E
L
L
L
G
----------------
L
L
E
L
I
E
E
P
S
--
G
K
Q
------
I
S
Q
S
---
I
L
L
L
L
Q
P
L
Q
T
V
I
Q
-------
K
---
L
H
N
-
K
A
------------
Y
S
I
G
L
A
L
S
T
L
W
N
------
Q
L
---
S
L
L
P
V
P
Y
SKMD
D
-
Y
G
L
C
Q
C
C
K
A
L
I
E
F
T
K
-------
P
----
F
V
-------
E
E
V
I
DNKENS
L
E
N
------
E
K
L
K
D
E
L
L
K
F
-
C
F
K
----------
S
--------
L
K
C
P
L
L
T
-
A
---
Q
F
F
D
---
P
F
R
Y
F
A
S
E
I
I
G
F
L
S
A
I
GHPFPKMKQL
A
-------------
D
S
M
A
S
L
A
Y
L
V
F
-
V
QGIHIDQLPMVLS
P
L
Y
L
L
Q
F
N
M
G
H
I
E
V
F
L
Q
R
T
--
E
E
S
V
I
S
K
G
L
E
L
L
E
N
S
L
L
R
-
I
E
D
N
S
LL
Y
Q
Y
L
E
I
K
------
S
F
L
T
V
P
------
Q
G
L
V
K
V
M
T
L
C
P
I
E
----
T
L
R
K
--
K
S
L
A
M
L
Q
L
Y
I
N
K
L
D
S
Q
G
K
Y
T
L
F
R
C
L
L
N
T
SNH
S
G
V
E
A
F
I
--
I
Q
N
I
K
N
Q
I
D
M
S
LKRKWFTG
P
Q
L
I
S
--------
L
L
D
L
V
L
FLPEGAET
D
----------------
L
L
Q
N
S
D
R
I
---
M
A
S
L
N
L
L
R
Y
L
V
I
K
D
N
E
-----
N
D
N
Q
T
G
L
W
T
E
-----
L
G
--
N
I
E
N
N
F
L
K
P
L
H
I
G
L
N
M
S
K
A
---------
H
Y
E
A
E
I
--
K
N
S
--
Q
E
A
Q
K
S
K
D
P
P
EMQL
K
V
L
H
S
A
L
F
T
F
D
L
I
E
S
V
L
A
R
V
E
E
L
I
E
I
K
T-------------------------------------------------------------------------------
49
Fugue
40.18
12%
-1
* C2 *
-
5IFE
-
SF3B1_HUMAN
C:
[463-1304]
NLPFLKPDDIQYFDKLL
V
D
V
D
ESE
E
Q
K
E
R
K
I
M
K
L
L
L
K
I
K
N
GT
P
P
M
R
K
A
A
L
R
Q
I
T
D
K
A
REFG
A
G
P
L
F
N
Q
I
L
P
L
L
M
SPTLE
D
Q
E
R
H
L
L
V
K
V
I
D
R
I
L
Y
K
L
DDLVRPY
V
H
K
I
L
V
V
I
EPLLIDED
Y
Y
A
R
V
E
G
R
E
I
I
S
N
L
A
K
A
A
G
L
A
T
M
I
S
T
M
RPDIDNMD
E
Y
V
R
N
T
T
A
R
A
F
A
V
V
A
S
A
L
GIPSL
L
P
F
L
K
A
V
C
K
SKKS
W
Q
A
R
H
T
G
I
K
I
V
Q
Q
I
A
I
L
M
GCAILPH
L
R
S
L
V
E
I
I
EHGLVDEQ
Q
K
V
R
T
I
S
A
L
A
I
A
A
L
A
E
A
A
TPYGIESFDSV
L
K
P
L
W
K
G
I
R
Q
HRG
K
G
L
A
A
F
L
K
A
I
G
Y
L
IPLMD
A
E
Y
A
N
Y
Y
T
R
E
V
M
L
I
L
I
R
E
F
QSPD
E
E
M
K
K
I
V
L
K
V
V
K
Q
C
C
G
TDGVE
A
N
Y
I
K
T
EI
L
P
P
F
F
K
HFWQ
H
R
M
A
L
D
R
R
N
Y
R
Q
L
V
D
T
T
V
E
L
A
N
K
VG
A
A
E
I
I
S
R
I
V
DDLKDEA
E
Q
Y
R
K
M
V
M
E
T
I
E
K
I
M
G
N
L
---
G
A
A
D
I
D
H
K
L
E
E
Q
L
I
D
---
G
I
L
Y
A
-
F
Q
E
Q
T
T
--------
E
D
S
V
M
L
N
G
F
G
T
V
V
N
A
L
G
K
R
V
K
-------
P
Y
L
P
Q
--
I
C
G
T
V
L
W
----------------
R
L
N
N
K
S
A
K
V
--
R
Q
Q
------
A
A
D
L
---
I
S
R
T
A
V
V
M
K
T
C
---------------
Q
-
E
E
------------
K
L
M
G
H
L
G
V
V
L
Y
E
------
Y
L
---
G
----------
E
-
E
Y
-
P
E
V
L
G
S
I
L
G
A
L
K
-------
A
----
I
V
-------
N
V
I
G
--------
M
------
H
K
M
T
P
P
I
K
D
L
-
L
P
R
----------
L
--------
T
P
I
L
K
N
R
H
E
---
K
V
Q
E
---
N
C
I
D
L
V
G
R
I
A
D
---------------
R
-------------
G
A
E
Y
V
----------------------------
S
A
R
E
W
M
R
I
C
F
E
L
--
L
E
L
L
K
A
H
K
K
A
I
R
R
A
T
V
N
T
-
F
G
Y
I
A
--
K
A
I
G
P
H
D
------
V
L
A
T
L
Q
------
N
R
V
C
T
T
V
A
I
A
I
V
A
----
E
T
C
S
PF
T
V
L
P
A
L
M
N
E
Y
R
V
P
E
L
N
V
Q
N
G
V
L
K
S
L
S
F
L
-----
F
E
Y
I
G
--
E
M
G
K
D
Y
I
Y
A
V
------------
T
P
--------
L
L
E
D
A
---------
L
----------------
M
D
R
D
L
V
H
R
---
Q
T
A
S
A
V
V
Q
H
M
S
L
G
V
Y
G
-----
F
G
C
------------
E
D
--
S
L
N
H
L
L
N
Y
V
W
P
N
V
F
E
T
-------------
S
P
H
V
I
--
Q
A
V
--
M
G
A
L
E
G
L
R
V
A
IG
P
C
R
M
L
Q
Y
C
LQGLFHPA
R
K
V
R
D
V
Y
W
K
I
Y
N
S
I
Y
I
G
SQDALIAHY
P
R
I
Y
N
D
DKNTYIRYELDYIL-----------------------------------------------
42
HHSearch
38.98
13%
-191
- C- -
-
3T0Y
-
?
C:
[99-136]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
F
L
-------
L
---
T
A
L
-
E
G
------------
F
T
P
T
E
A
A
Q
I
L
D
--------------------------
C
D
F
G
E
V
E
R
L
I
G
D
A
Q
-------
A
----
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
38.58
14%
-233
- C3 -
-
2K27
-
PAX8_HUMAN
A:
[24-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
P
E
V
V
R
Q
R
I
V
-------
D
---
L
A
H
-
Q
G
------------
V
R
P
C
D
I
S
R
Q
L
R
--------------------------
V
S
H
G
C
V
S
K
I
L
G
R
Y
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
36.23
14%
-165
- C3 -
-
1TC3
2
TC3A_CAEEL
C:
[18-45]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
-
L
N
------------
V
S
L
H
E
M
S
R
K
I
S
--------------------------
R
S
R
H
C
I
R
V
Y
L
K
D
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
35.35
10%
17
- C2 -
-
3KZW
-
?
A:
[22-515]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SNA
M
N
F
K
L
NNTLSNEIN
T
L
I
I
G
I
P
EHLNQLE
R
I
S
F
NHIDI
T
E
S
L
E
R
L
K
H
Q
H
---
I
I
G
S
K
V
G
K
I
Y
T
T
A
F
D
V
QD
Q
T
Y
R
L
I
T
V
G
L
G
N
--------
L
K
T
R
S
Y
Q
D
M
L
K
I
W
G
H
L
F
Q
Y
I
K
-------
S
E
H
I
E
--
D
T
Y
L
L
M
D
SFISKYDQ
L
S
D
V
L
M
A
C
G
I
Q
S
E
R
A
T
Y
--
E
F
D
------
H
Y
K
S
---
S
K
K
A
P
F
K
T
N
L
N
L
I
SESLIEL
D
---
F
I
H
-
E
G
------------
I
S
I
G
Q
S
I
N
L
A
R
D
------
F
S
N
MP
P
----------
N
-
V
L
T
P
Q
T
F
A
E
D
I
V
N
H
F
-------
K
NTK
V
K
V
-------
D
V
K
D
--------
Y
------
D
T
L
V
S
E
G
F
G
L
-
L
Q
A
----------
V
G
KGSKH
K
P
R
L
V
T
I
T
Y
-
N
GKD
K
D
E
A
---
P
I
A
L
V
G
K
G
I
T
Y
---------------
D
SGGYSIKTKNGMA
T
M
K
F
D
M
C
G
A
A
N
-
V
------------------
V
G
I
I
E
A
A
S
R
L
Q
L
P
V
--
N
I
V
G
V
L
A
C
A
E
N
M
I
N
E
A
S
M
-
K
P
D
D
V
--
F
T
A
L
S
G
E
------
T
V
E
----------------
V
M
N
T
D
A
----
E
G
R
L
--
V
L
A
D
A
V
F
Y
A
N
Q
Y
Q
P
--
S
V
I
M
D
F
A
T
L
T
G
A
-----
A
I
V
A
L
--
G
D
D
K
A
A
A
F
E
S
------------
N
S
--------
K
V
I
L
N
---------
D
----------------
I
L
Q
I
S
S
E
V
D
E
M
V
F
E
L
P
I
T
A
T
E
R
A
S
I
K
H
SDIAD
L
V
N
H
T
N
G
Q
G
K
-----
A
L
--
F
A
A
S
F
V
T
H
F
S
G
Q
T
P
H
I
H
F
D
IAGPATTNK
A
S
Y
N
G
P
--
K
G
P
--
T
G
F
M
I
P
T
I
V
Q
W
L
K
Q
Q----------------------------------------------------------------------------------------------------------
21
HHSearch
35.21
14%
-153
- C3 -
-
2ELH
-
DAN_DROME
A:
[21-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
L
T
P
R
D
K
I
H
A
I
-------
Q
---
R
I
H
-
D
G
------------
E
S
K
A
S
V
A
R
D
I
G
--------------------------
V
P
E
S
T
L
R
G
W
C
K
N
E
D
-------
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
34.52
24%
93
- C3 -
-
5HLB
1
PBPB_ECOLI
A:
[128-273]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
M
E
N
N
R
Q
F
G
F
F
R
L
D
P
R
LIT
M
I
S
S
P
--
N
G
E
Q
R
L
F
----------------
V
P
R
S
G
F
P
D
L
--
L
V
D
------
T
L
------------
L
A
T
E
D
R
-------
H
---
F
Y
E
H
D
G
------------
I
S
L
Y
S
I
G
R
A
V
L
A
------
N
L
---
T
----------
A
-
G
R
T
V
Q
G
A
S
T
L
T
Q
Q
L
V
-------
K
-------------
N
L
F
L
--------
S
SERSY
W
R
K
A
N
E
A
Y
M
A
L
-
I
M
D
----------
A
--------
R
Y
S
K
D
R
I
-
L
---
E
L
Y
M
---
N
E
V
Y
L
G
----
Q
---------------
S
-------------
G
D
N
E
I
R
G
F
P
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
34.16
13%
-132
- C3 -
-
2LFW
-
?
A:
[95-140]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
L
S
R
Q
A
L
L
-------
L
---
T
A
M
-
E
G
------------
F
S
P
E
D
A
A
Y
L
I
E
--------------------------
V
D
T
S
E
V
E
T
L
V
T
E
A
L
-------
A
----
E
I
-------
E
K
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
32.85
24%
-52
- C3 -
-
3P1B
-
?
A:
[11-115]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
L
Y
E
M
Y
------
L
Q
D
E
D
A
------
F
H
S
K
R
D
Y
P
H
K
K
V
F
T
E
L
Q
K
L
R
K
--
I
F
F
P
D
F
F
M
K
H
Q
K
I
T
E
S
H
I
A
S
E
L
T
K
L
V
D
Y
-----
I
K
D
S
V
--
T
A
Y
N
D
E
L
F
A
H
------------
Q
C
--------
V
M
A
I
L
---------
E
----------------
K
L
P
S
I
K
R
T
---
L
-
K
T
D
L
I
A
A
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
32.27
10%
-268
- C3 -
-
2M8E
-
?
A:
[19-49]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
---
L
H
K
-
S
G
------------
S
S
L
G
A
I
S
K
R
L
K
--------------------------
V
P
R
S
S
V
Q
T
I
V
R
K
Y
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
30.57
24%
-46
- C3 -
-
3Q1X
-
?
A:
[10-111]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
L
Y
E
M
Y
------
L
Q
D
E
D
A
------
F
H
S
K
R
D
Y
P
H
K
K
V
F
T
E
L
Q
K
L
R
K
--
I
F
F
P
D
F
F
M
K
H
Q
K
I
T
E
S
H
I
A
S
E
L
T
K
L
V
D
Y
-----
I
K
D
S
V
--
T
A
Y
N
D
E
L
F
A
H
------------
Q
C
--------
V
M
A
I
L
---------
E
----------------
K
L
P
S
I
K
R
T
---
L
-
K
T
D
L
I
A
A
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------