@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U382: (2017-12-24 )
MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSSSYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVLCMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKQFHLRYLSRLKRNSRSSIATNRVFQMPLRCPTQTASLRG
Atome Classification :
(20 SA)
---.........10.--------...------....--20----.----------.-----......30........40........50...-----.....60........-70........80........90--------------..-......-----.100.....----..110.......120.........130...--....140-----........150..---.....160--------........170.------------------------.....--------.180.......190........---200.......210..-.....-220....-----...230-....---...240.......--250.-----------......260.....--..270--------.........280..-------.-....290---...----.....----.300...------....310..-.--....320......--.330.......340.--......350.......360.......370......--.380.......--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---MDN
H
T
R
K
L
LGLT--------DK
H
------
L
FF
D
--
E
E
----
W
----------
L
-----
I
E
K
E
YKGV
Q
A
Q
F
I
KGKLDD
S
S
S
Y
C
E
H
C
R
S
V
R
-----
I
I
RNGSYT
T
R
T
Q
M
L
K
-
V
K
E
K
L
T
I
L
E
L
K
R
T
R
F
L
C
H
DCG---------------RT-FSAKTD-----
L
V
D
E
H
H
Q
L
T
----
K
E
L
K
Q
V
I
L
M
E
L
Y
E--NQ
S
R
K
L
I
A
K
K
Y
FVSD--
G
T
V
T
R
I
------
L
R
E
A
T
K
H
YQP
R
M
N
---F
L
P
T
V
L
C
---------
M
D
E
F
K
S
M
N
SVSG------------------------
S
M
S
F
I
--------
C
VDGTT
N
Q
L
F
T
I
-
L
ED
R
R
L
Y
K
L
---
T
Q
Y
F
L
RFPRKA
R
L
K
V
-
K
Y
L
V
M
-DM
N
A
S
Y
C
-----
Q
L
L
K
T
V-FPN
A
---
E
I
V
T
D
R
F
H
I
V
Q
H
I
--
N
R
S
F
-----------
N
Q
L
R
V
Q
I
M
N
R
F
RTS--HSE----------
N
Q
K
K
Y
R
R
L
K
R
Y
W
K
L
-------
L
-LKDST-----
T
L
E
----
P
L
K
R
H
----
Y
H
R
L
F
KR------PI
S
Q
T
E
I
V
D
-
E
--
L
L
S
Y
N
E
E
L
R
T
A
Y
H
--
F
C
Q
L
L
R
Y
Y
F
V
KRGT
E
--
G
F
Q
E
T
L
K
Q
F
H
L
R
Y
L
S
R
LKRNSRSSIATN
R
V
F
QMPL--RCPTQTASLRG--------------------------------------
34
Fugue
61.72
19%
18
- C1 -
-
4CZX
2
PAN2_NEUCR
A:
[1-324]
P
H
M
M
D
S
R
D
W
T
Q
L
G
C
V
A
Y
PSPIHP
D
Y
H
AGPAS
T
I
A
F
D
--
N
Q
DE
L
L
W
----------
I
-----
G
T
Q
--
K
G
F
A
G
S
F
I
G
R
E
L
-------
K
R
F
T
A
F
R
-----
I
---------------------------------------------------------------------
H
P
E
T
D
----
G
P
L
R
Q
F
L
F
V
D
------------
K
G
V
I
F
L
G
S
--
R
S
V
Y
M
A
------
A
R
S
G
V
P
I
W
S
I
R
H
E
---
S
---------------
M
Q
D
L
R
A
M
S
F
T
S
K
------------------------
G
T
S
E
I
--------
L
V
A
G
W
Q
N
K
M
L
V
I
-
D
V
N
K
G
--
E
V
---
V
K
E
L
P
T
Q
D
Q
Y
S
F
L
K
M
S
R
Y
I
C
A
-
A
T
N
K
G
T
V
-----
N
I
L
D
P
I
T
F
T
I
K
---
K
Q
W
Q
A
H
G
A
F
I
N
D
L
--
D
T
S
------------
N
D
F
I
V
T
C
G
G
S
H
R
Q
T
--
H
N
T
----------
P
A
I
----
L
D
P
Y
V
K
V
-------
F
D
L
K
N
M
S
-----
A
M
N
----
P
V
P
F
A
PLAA
H
V
R
M
H
P
R
------
M
L
T
T
A
I
V
V
N
-
Q
----------
A
G
Q
I
H
--
V
T
D
L
L
N
P
S
N
S
Q
V
C
Y
T
--
Q
P
Q
G
V
V
L
H
F
D
V
S
------
R
T
G
E
G
K
A
L
A
D
N
K
H
N
T
Y
V
--
W
G
S
P
N
K
I
Q
F
T
E
--------------------------------------
27
Fugue
58.95
15%
51
- C5 -
-
3BTP
1
VIRE2_AGRFC
A:
[112-517]
-------
R
R
T
-------------------------
D
--
E
Y
----
I
----------
L
-----
V
R
Q
T
G
Q
D
K
F
A
G
T
T
K
C
N
L
D
H
L
P
T
K
A
E
F
N
A
S
C
R
-----
L
Y
R
D
G
V
G
N
Y
Y
P
P
P
L
A
-
F
E
R
I
D
L
P
E
Q
L
A
A
Q
L
L
E
P
R
E
Q
S
---------------
K
Q
C
F
Q
Y
K
L
E
-----
V
W
N
R
A
H
A
E
M
GITG
T
D
I
F
Y
Q
T
D
K
N
I
K
L
--
D
R
N
Y
K
L
R
P
E
D
R
Y
I
Q
----
T
E
K
Y
G
------
R
R
E
I
Q
K
R
Y
E
H
Q
F
Q
AGS
L
L
P
D
I
L
I
---------
K
T
P
Q
N
D
I
H
F
S
Y
R
------------------------
F
A
G
------------
D
A
Y
A
N
K
R
F
E
E
-
F
E
R
A
I
K
T
K
Y
GSD
T
E
I
K
L
K
S
K
S
G
I
M
H
D
S
-
K
Y
L
E
S
W
E
R
G
S
A
D
I
-----
R
F
A
E
F
A
---
G
E
---
N
R
A
Q
F
P
A
A
T
V
N
M
G
--
R
Q
P
M
-----------
T
R
D
R
H
V
S
V
D
Y
L
L
Q
N
LP
N
S
P
----------
W
T
Q
A
L
K
E
G
K
L
W
D
R
V
-------
Q
-
V
L
A
R
D
GN
R
Y
M
S
P
S
----
R
L
E
Y
S
----
D
P
E
H
F
T
Q
------
L
M
D
Q
V
G
L
P
V
-
S
--
M
G
R
Q
S
H
A
F
D
R
Q
A
A
--
V
I
V
A
D
G
P
N
L
R
E
V
P
D
L
--
S
-
P
E
K
L
S
Q
K
D
V
L
I
A
D
R
N
E
K
G
Q
R
T
G
T
Y
T
N
V
V
E
Y
E
R
L
MM
K
L
P
S
D
A
A
Q
L
L
A
--------------------------------------
30
Fugue
55.19
12%
2
- C4 -
-
1BXS
1
AL1A1_SHEEP
A:
[8-501]
--D
V
P
A
P
L
T
-
N
L
Q
F
K
--------
Y
T
K
------
I
F
I
N
--
N
E
----
W
H
S
SVSG
K
K
F
P
V
-----
F
N
P
A
T
E
E
K
L
C
E
V
E
E
G
D
K
E
D
V
D
K
A
V
K
A
A
R
Q
A
F
QIGSP
W
R
T
M
D
A
S
E
R
G
R
L
L
N
K
-
L
A
D
L
I
E
R
D
R
L
L
L
A
T
M
E
A
M
N
G
G
---------------
K
L
-
F
S
N
A
Y
L
M
D
L
G
G
C
I
K
T
L
R
Y
C
A
----
G
W
A
D
K
I
-
Q
G
R
T
I
P
--
M
D
---
G
N
F
F
T
Y
T
R
S
E
PV
G
V
C
G
Q
I
I
P
WNF
P
L
L
M
F
L
W
K
I
G
P
A
L
S
---
C
G
N
T
V
V
V
K
P
A
EQTP
L
T
A
L
H
M
G
S
L
I
K
E
A
G
FPPGV
V
N
I
V
P
G
Y
G
PT
A
G
A
A
I
S
S
HM
D
V
D
K
V
--------
A
F
T
G
S
T
E
V
G
K
L
I
-
K
E
A
A
G
K
S
N
L
---
K
R
V
S
L
E
L
G
G
K
S
P
C
I
V
--
F
A
D
A
-
D
L
D
N
A
V
E
-----
F
A
H
Q
G
V
-
F
Y
H
Q
GQC
C
I
A
A
S
R
L
F
V
E
E
S
I
--
Y
D
E
F
-----------
V
R
R
S
V
E
R
A
K
K
Y
V
L
G
--
N
P
L
TPGVS
Q
G
P
Q
I
D
K
E
Q
Y
E
K
I
L
D
L
I
E
S
-------
G
-
K
K
E
G
A
-----
K
L
E
CGG
G
P
W
G
----------
N
K
G
------
Y
F
I
Q
P
T
V
F
S
-
D
--
V
T
D
D
M
R
I
A
K
E
E
I
F
GP
V
Q
Q
I
M
K
F
K
S
L
D
D
V
I
K
--
R
A
N
N
T
F
Y
G
L
S
A
G
I
F
T
N
D
I
D
K
A
I
T
V
S
S
A
L
Q
S
G
T
V
W
V
--
N
C
Y
S
V
--
V
S
A
Q
C
P
F
G
G
F
K
MSGNGRELG
E
Y
G
F
H
E
Y
T
E
V
K
T
V
T
I
K
I
SQKNS
10
HHSearch
48.12
20%
-255
- C6 -
-
1PDN
2
PRD_DROME
C:
[15-58]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
L
P
----
N
N
I
R
L
K
I
V
E
M
A
A
D
--
G
I
R
P
C
V
I
S
R
Q
L
R
V
S
H
--
G
C
V
S
K
I
------
L
N
R
Y
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
47.31
15%
22
- C4 -
-
5JP6
-
?
A:
[23-379]
---
M
S
Q
I
G
S
S
V
R
Q
A
V
--------
S
D
N
------
Q
S
A
Q
T
L
V
E
----
W
----------
E
N
SEAN
P
E
A
L
F
A
N
W
R
H
E
F
M
V
D
S
S
K
R
E
S
M
K
T
E
L
C
K
E
L
Q
-----
A
L
P
------
A
Q
D
L
T
L
-
F
E
N
E
I
R
---
D
E
N
N
R
A
L
V
S
G
C
K
---------------
E
E
-
L
L
A
Q
--------
V
D
E
H
F
D
E
Q
----
R
E
S
M
S
V
P
G
H
A
L
K
A
--
V
Q
S
R
N
----
S
F
R
F
P
D
--
N
T
Q
K
R
D
------
M
S
N
G
Y
M
A
V
R
G
D
V
A
---
R
K
E
V
V
L
T
---------
F
D
D
--
G
P
H
G
L
Y
T
------------------------
D
A
I
L
R
--------
A
L
K
E
V
N
A
K
A
M
F
F
-
A
T
G
K
S
V
R
T
N
---
P
E
A
L
K
R
V
A
A
D
G
H
V
I
G
-
S
H
----
S
I
T
L
T
F
D
-----
E
A
A
A
E
V
-
R
G
G
H
---
Q
A
V
F
D
V
L
G
W
V
D
P
V
--
F
R
F
Y
-----------
G
E
T
S
K
D
L
K
A
F
L
K
T
K
--
S
T
G
----------
E
F
A
--------
W
N
I
-------
E
-
S
D
D
W
R
-----
T
Q
S
-------------
N
E
Q
L
L
A
R
------
V
L
A
N
V
E
S
Q
G
-
R
G
I
V
L
F
H
D
I
Q
R
R
T
A
E
I
--
M
P
Q
F
L
R
E
L
Y
N
R
------
G
Y
----------
S
V
V
L
L
T
A
A
D
P
S
A
K
Y
N
S
K
L
V
K
--------------
R
K
--------------------------------------
33
Fugue
46.31
13%
-5
- C4 -
-
1OTH
1
OTC_HUMAN
A:
[1-321]
--K
V
Q
L
K
G
R
D
L
L
T
L
K
--------
N
----------
F
T
--
G
E
----
E
----------
I
-----
K
Y
M
L
W
L
S
A
D
L
K
F
R
I
K
Q
K
G
E
Y
L
P
L
L
Q
G
K
S
L
G
M
-----
I
F
E
K
R
S
T
R
T
R
L
S
T
E
T
-
G
F
A
L
L
------
G
G
H
P
C
F
L
T
T
Q
---------------
D
I
-
H
L
G
V
N
E
-----
S
L
T
D
T
A
R
V
L
----
S
S
M
A
D
A
V
L
A
R
V
Y
K
--
Q
S
D
L
D
T
L
A
K
E
A
-------
S
-
I
P
I
------
I
N
G
L
S
D
-
L
Y
H
P
I
Q
---
I
L
A
D
Y
L
T
---------
L
Q
E
H
Y
S
--
S
L
K
G
------------------------
L
T
L
S
W
--------
I
G
D
G
-
N
N
I
L
H
S
I
-
M
M
S
A
A
K
F
-
G
---
M
H
L
Q
A
A
T
P
K
G
Y
E
P
D
--------------
A
-----
S
V
T
K
L
A
-
E
Q
Y
A
---
K
E
N
G
T
K
L
L
L
T
N
D
P
--
L
E
A
A
-----------
H
G
G
N
V
L
I
T
D
T
W
I
S
M
--
G
-
R
----------
E
E
E
K
K
K
R
L
Q
A
F
Q
G
Y
-------
Q
-
V
T
-------------------------
M
K
T
A
K
V
------
A
-
A
S
D
W
T
F
L
-
H
--
C
L
P
R
K
-
P
---------------------
E
E
--
V
D
D
E
V
F
Y
S
P
R
S
L
V
F
P
E
A
E
N
R
K
W
T
I
M
A
V
M
V
S
L
L
T
D
Y
--
S
P
Q
L
Q
K
P
K
F
----------------------------------------
20
HHSearch
46.28
23%
-238
- C6 -
-
6PAX
-
PAX6_HUMAN
A:
[16-58]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
P
L
P
----
D
S
T
R
Q
R
I
V
E
L
A
H
S
--
G
A
R
P
C
D
I
S
R
I
L
Q
V
S
N
--
G
C
V
S
K
I
------
L
G
R
Y
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
44.84
12%
74
- C2 -
-
4DVZ
-
CAGA_HELPY
A:
[308-829]
--L
M
G
S
H
N
G
K
V
S
L
L
Y
--------
A
G
D
---------
K
--
H
D
----
W
----------
N
-----
A
T
V
G
Y
K
D
N
V
A
T
L
I
N
V
H
M
K
N
G
S
G
L
V
I
A
G
G
E
K
G
-----
I
N
N
P
S
F
Y
L
Y
K
E
D
Q
L
T
G
S
Q
R
A
L
S
Q
E
E
I
R
N
K
V
D
F
M
E
F
L
A
Q
N
NTKLDNLS
E
K
E
K
E
K
F
-
Q
N
E
I
E
D
-----
F
Q
K
D
S
K
A
Y
L
----
D
A
L
G
N
D
R
I
A
F
V
S
K
--
K
D
T
K
H
S
A
L
I
T
E
F
-
N
N
--
G
D
L
S
Y
T
------
L
K
D
Y
E
K
N
V
T
L
Q
G
S
---
L
K
H
D
G
V
M
---------
F
V
D
Y
S
F
N
K
V
A
V
F
------------------------
N
L
P
D
L
NNLAITS
F
V
R
R
N
L
E
N
K
L
T
A
K
G
L
S
L
Q
E
A
N
K
L
---
I
K
D
F
L
S
S
N
K
E
L
A
G
K
A
-
L
N
F
N
K
-
A
V
A
E
A
K
S
T
GNY
D
E
V
K
K
A
Q
-
K
D
L
E
---
K
S
L
R
K
R
E
H
L
E
K
E
V
--
E
K
K
L
E
S
K
SGNKK
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
--
A
N
R
----------
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
-------
K
-
R
E
L
S
D
-----
K
L
E
----
K
I
S
K
D
----
L
K
D
F
S
K
S
F
D
E
F
K
N
F
S
K
A
E
E
T
L
K
-
A
--
L
K
G
S
V
K
D
L
G
I
N
P
E
--
W
I
S
K
V
E
N
L
N
A
A
L
N
E
F
K
N
G
D
F
S
K
V
T
Q
A
K
S
D
L
E
N
S
V
K
D
V
I
I
N
Q
K
V
T
D
K
V
D
N
L
N
Q
--
A
V
S
V
A
K
A
M
G
D
F
S
R
V
E
Q
V
L
A
D
L
K
N
F
S
K
E
Q
L
A
Q
Q
A
Q
K--------------
1
PsiBlast_PDB
42.58
21%
-138
- C6 -
-
5DSG
9
ACM4_HUMAN (first)
A:
[12-154]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
V
F
I
A
T
V
T
G
------------------------
S
L
S
L
V
--------
T
V
V
G
N
I
L
V
M
L
S
I
-
K
V
N
R
Q
L
Q
T
V
---
N
N
Y
F
L
F
S
L
A
C
A
D
L
I
I
-
G
A
F
S
M
-
N
L
Y
T
V
Y
-------
I
I
K
G
Y
-
W
P
L
G
---
A
V
V
C
D
L
W
L
A
L
D
Y
V
V
S
N
A
S
V
-----------
M
N
L
L
I
I
S
F
D
R
Y
F
C
V
--
T
K
P
----------
L
T
Y
P
A
R
R
T
T
K
M
A
G
L
-------
M
-
I
A
A
A
W
-----
V
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
39.54
22%
-94
* C6 *
-
3G1C
-
?
A:
[38-98]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
L
S
----
L
S
Q
R
F
E
V
A
K
M
L
R
E
--
H
R
T
Y
L
D
I
A
E
K
T
G
A
S
T
--
A
T
I
S
R
V
------
N
R
S
L
N
Y
G
N
-
D
G
Y
D
---
R
V
F
E
R
L
G
---------
M
L
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
38.96
29%
-150
- C6 -
-
4A8E
-
XERA_PYRAB
A:
[11-79]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
I
E
-
E
--
F
A
T
Y
L
E
L
E
G
K
S
R
N
--
T
V
R
M
Y
T
Y
Y
I
S
K
F
F
E
E
--
G
H
S
P
T
A
R
D
-
A
L
R
F
L
A
K
L
K
R
K
G
Y
S
T
R
S
L
N
L
V
I
Q
------------------------------------------------------
9
HHSearch
35.86
19%
-116
- C6 -
-
2ELH
-
DAN_DROME
A:
[22-64]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
----
P
R
D
K
I
H
A
I
Q
R
I
H
D
--
G
E
S
K
A
S
V
A
R
D
I
G
V
P
E
--
S
T
L
R
G
W
------
C
K
N
E
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
33.75
29%
-101
- C7 -
-
3WWN
-
?
B:
[20-33]
----------------------------------------------------------------------------------------------------------------------------
G
E
L
V
V
C
E
D
C
G
---------------
A
E
-
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
33.44
29%
-108
* C7 *
-
3WWL
-
LYSW_THET8
A:
[20-33]
----------------------------------------------------------------------------------------------------------------------------
G
E
L
V
V
C
E
D
C
G
---------------
A
E
-
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
28.16
28%
105
- C6 -
-
1HLV
-
CENPB_HUMAN
A:
[7-51]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
T
----
F
R
E
K
S
R
I
I
Q
E
V
E
E
N
P
D
L
R
K
G
E
I
A
R
R
F
N
I
P
P
--
S
T
L
S
T
I
------
L
K
N
K
R
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
28.05
25%
21
- C6 -
-
1TPZ
-
IIGP1_MOUSE
A:
[313-415]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
F
Y
R
T
V
--
F
G
V
----------
D
E
T
S
L
Q
R
L
A
R
D
W
E
I
E
V
D
Q
V
E
A
M
-
I
K
S
P
A
-----
V
F
K
----
P
T
D
E
E
T---
I
Q
E
R
L
S
R
------
Y
I
Q
E
F
C
L
A
N
G
Y
--
L
L
P
K
N
S
F
L
K
E
I
F
Y
------
L
K
Y
Y
F
L
D
M
V
T
E
--
D
A
K
T
L
L
K
E
I
C
L
K
-
L
G
R
----------------------------------------------------------------------
4
PsiBlast_PDB
27.43
25%
21
- C6 -
-
1TQ2
-
IIGP1_MOUSE
A:
[313-415]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
F
Y
R
T
V
--
F
G
V
----------
D
E
T
S
L
Q
R
L
A
R
D
W
E
I
E
V
D
Q
V
E
A
M
-
I
K
S
P
A
-----
V
F
K
----
P
T
D
E
E
T---
I
Q
E
R
L
S
R
------
Y
I
Q
E
F
C
L
A
N
G
Y
--
L
L
P
K
N
S
F
L
K
E
I
F
Y
------
L
K
Y
Y
F
L
D
M
V
T
E
--
D
A
K
T
L
L
K
E
I
C
L
K
-
L
G
R
----------------------------------------------------------------------
8
HHSearch
25.88
18%
-93
- C3 -
-
2AKL
-
?
A:
[25-57]
-------------------------------------------------------------------------------
S
T
L
P
P
C
P
Q
C
N
S
E
Y
-----
T
Y
E
D
----------------------
G
-
A
L
L
V
C
P
E
C
A
---------------
H
E
-
W
S
P
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
25.01
23%
-143
- C3 -
-
5JB3
-
RS27A_PYRFU
Y:
[18-47]
--------------------------------------------------------------------------------
K
N
K
F
C
P
R
C
G
P
G
V
-----
F
M
A
D
----------------------
H
G
D
R
W
A
C
G
K
C
G
---------------
Y
T
-
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
24.71
18%
-67
* C3 *
-
1QYP
-
A:
[15-54]
---------------------------------------------------------------------------------
K
I
T
C
P
K
C
G
N
D
T
-----
A
Y
W
W
E
M
Q
T
R
A
-------
G
D
E
-----
P
S
T
I
F
Y
K
C
T
K
C
G
---------------
H
T
-
W
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------