@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U3P0: (2017-12-25 )
METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTNKLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVNNNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPKEKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFSRN
Atome Classification :
(20 SA)
---------------------.........10........20......-.-----.30........40........50........-60........70........80........--90.....----...100.......------110.......120.......130-.........140.......--150.-.--------.....160.......170-----.......180.......190.........200.......210.....--..220.......230---.......240.......-----250.......260.......270.......280.......290......-...300.---.....--.310------------....----..----.320.......330.......340.------------......350....--------..-.360..--------.....370.......380.......390.......400-------........410.......420--.......430.......440.......450.......460.......470.......480.......490......--.-500.......510...
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------ME
T
T
D
T
L
L
Q
L
L
Q
E
A
H
KT
N
Q
A
Q
Q
Q
T
I
Q
N
-
L
-----
T
T
E
I
Q
L
L
N
E
K
V
N
Y
L
T
N
K
L
FGR
S
K
E
T
L
F
E
ETN-G
Q
L
N
L
FSDE
E
I
S
V
SVPEA
A
A
T
I
I
PVKGHQ
R
--
V
VGTKAD----
K
I
KHLPITEKEHL------L
P
L
E
E
Q
F
C
E
H
C
G
S
Q
M
K
D
I
G
R
T
---
K
V
R
E
E
I
R
F
H
Q
A
M
L
D
C
L
T
H
Y
--
Q
H
T
Y
-
C
--------
C
K
S
C
E
K
E
G
L
S
S
F
K
K
AIVP-----K
P
L
ISNSLGS
N
S
L
V
A
E
T
I
--
R
M
K
FGQKVP
A
Y
R
QENYWKQTHGLDISR--DNIT
N
W
H
I
K
A
V
Q
N
A
L
---
D
P
L
G
E
R
LRVNN
N
Q
E
E
IL-----HGDET
S
Y
R
V
I
ESAKTD
T
Y
Y
W
Q
FCTGKDSQH
P
I
V
Y
Y
HHDESR--AGDV
P
K
-
T
F
L
K
E
FT---
G
Y
L
H
C--DGYS------------G
Y
N
A
----
V
E
----
S
V
R
L
V
Y
C
F
A
H
V
R
R
K
F
F
E
AIPKEKKN------------TDI
P
A
A
Q
A
V
K
Q
L
D
--------
K
W
-
F
V
L
E
K
K
--------WKDF
S
P
E
K
R
L
S
C
R
Q
Q
E
L
R
P
L
F
I
A
F
Y
E
W
M
A
T
I
D
P
V
A
K
S
--------
K
L
D
A
A
V
Q
Y
A
C
K
LRSGF
E
P
I
FE--DG
R
L
E
LTN
N
R
A
E
R
N
I
K
E
L
V
IGRKNWLHSTSLEGARTS
G
I
I
L
S
V
Y
K
T
AELNGL
N
P
V
K
Y
L
E
F
L
F
DKIPNLPVL
S
A
E
T
L
--
D
-
Q
LLPW
N
K
D
V
Q
Q
H
FSRN
51
Fugue
60.18
14%
-20
- C5 -
-
4YZF
1
B3AT_HUMAN
A:
[381-887]
-----------------------------
G
L
V
R
D
I
R
R
R
Y
P
Y
Y
L
S
D
I
T
D
A
F
-----
S
P
Q
V
L
A
A
V
I
F
I
Y
F
A
A
L
S
P
A
I
T
F
G
G
L
L
G
E
K
T
R
-
N
Q
M
G
---
V
S
E
L
L
I
S
T
A
V
Q
G
I
L
F
A
L
L
-
G
A
Q
P
L
L
V
V
G
F
S
G
P
L
L
V
F
E
E
A
F
F
S
F
C
E
T
N
G
L
E
Y
I
V
G
R
V
W
I
G
F
W
L
I
L
L
V
V
L
V
V
A
F
E
G
S
F
---
L
V
R
F
I
S
R
Y
T
Q
E
I
F
S
F
L
I
S
L
--
I
F
I
Y
-
E
--------
T
F
S
K
L
I
K
I
F
Q
D
H
P
L
Q
K
T
Y
-----
L
P
--
N
T
A
L
L
S
L
V
L
M
A
G
T
----
F
F
F
A
M
M
L
R
K
F
K
N
S
S
Y
F
P
G
K
L
R
R
V
I
G
D
--
F
G
V
P
I
S
I
L
I
M
V
L
V
D
F
F
IQ
D
T
Y
T
Q
K
L
S
V
P
D
G
F
K
V
V
I
-----
H
P
---------------------
L
G
L
R
S
E
F
P
I
W
M
M
F
A
S
A
L
P
--
A
L
L
V
F
I
-
L
I
F
L
E
S
Q
---
I
T
T
L
I
--
V
S
K
P
------------
E
R
K
M
----
V
K
GSG
F
H
L
D
L
L
L
V
V
G
M
G
G
V
A
A
L
F
G
M
P
-------------------
W
L
S
A
T
T
V
R
S
V
T
--------
H
A
-
N
A
L
T
V
M
--------
I
Q
E
V
K
E
Q
R
I
S
G
L
L
V
A
V
L
V
G
L
S
I
L
M
E
P
I
L
S
R
I
---
P
L
A
--------
V
L
F
G
I
F
L
Y
M
G
V
T
S
L
S
G
I
Q
L
F
D
--
R
I
L
L
L
F
K
P
P
K
Y
H
P
D
V
P
Y
V
K
R
V
K
T
W
R
M
H
L
F
T
G
I
Q
I
I
C
L
A
V
L
W
V
V
K
S
T
P
A
S
L
A
L
P
F
V
L
I
L
T
V
P
L
R
R
V
L
L
P
L
I
F
R
N
V
E
L
--
Q
-
C
L
D
-------------
44
Fugue
59.39
19%
46
* C5 *
-
5C3M
-
?
B:
[5-438]
-------------------L
K
M
A
T
I
G
G
G
S
S
Y
T
P
E
L
V
E
G
L
I
K
R
Y
H
E
L
P
--------
V
G
E
L
W
L
V
D
I
P
E
G
K
E
K
L
E
I
V
G
A
L
A
K
R
M
V
E
K
A
G
-
V
P
I
------
E
I
H
L
T
L
D
R
R
R
A
L
----
E
G
A
D
F
--
V
T
T
Q
F
------
R
V
G
G
L
E
A
R
A
K
D
E
R
------
I
P
L
K
Y
G
V
I
---
G
Q
E
T
N
--
G
P
G
---
G
L
F
K
G
L
R
T
I
P
V
I
L
D
I
I
R
D
M
--
E
E
---------------------------
L
C
P
-----
D
A
W
L
I
N
F
T
N
P
A
G
M
V
T
E
A
V
--
L
R
Y
T
K
Q
E
------------------------------
K
V
V
G
L
C
N
---
V
P
I
G
M
R
M
G
V
A
K
L
L
----------
G
V
D
A
D
R
V
H
I
D
F
A
G
L
N
H
M
V
F
G
L
H
V
Y
L
D
G
V
E
V
T
E
K
V
I
D
L
V
A
H
--
P
L
G
W
E
P
-
D
F
L
K
G
L
----
K
V
L
P
C
--
P
Y
H
R
------------
Y
Y
Y
----------------------
Q
T
D
K
M
L
A
E
E
L
E
A
A
K
------------
T
K
G
T
R
A
E
V
V
Q
Q
L
E
--------
K
E
-
L
F
E
--
L
--------
Y
K
D
P
R
G
G
A
Y
Y
S
---
D
A
A
C
S
L
I
S
S
I
Y
N
D
K
R
D
I
Q
P
V
N
T
R
NNGAIASI
P
P
E
S
A
V
E
V
N
C
V
I
T
-------
K
--
D
G
P
K
P
I
A
V
G
D
L
P
V
A
V
R
G
L
V
Q
Q
I
K
S
F
-
E
R
V
A
A
E
A
A
V
T
-
G
D
Y
Q
T
A
L
V
A
M
T
I
N
P
L
------------
V
P
S
-
D
T
I
A
K
Q
M
L
--
D
-
E
M
L
E
A
H
K
E
H
L
P
Q
F
F
--
45
Fugue
52.58
12%
-20
- C3 -
-
1OCK
-
?
A:
[1-412]
------------------------
M
I
S
L
A
D
L
Q
R
R
I
E
T
G
E
L
S
P
N
A
A
I
A
Q
-
S
-----
H
A
A
I
E
A
R
E
K
E
V
H
A
F
V
R
H
D
K
S
A
R
A
Q
A
-----
S
-
G
P
L
R
---------
G
I
A
V
G
I
K
D
I
I
D
T
A
N
M
P
T
--
E
M
G
S
E
I
Y
----
R
-
G
W
Q
P
R
S
D
A
P
V
V
------
M
M
L
K
R
A
G
A
-------
T
I
I
G
K
T
---
T
T
T
A
F
A
S
R
D
P
T
A
T
L
N
P
H
N
T
--
G
H
S
P
----------------
G
G
S
S
S
G
S
A
A
A
V
G
-----
A
G
M
I
P
L
A
L
G
T
Q
T
---------------
G
G
S
V
I
R
P
A
A
Y
C
G
T
A
A
I
K
P
S
F
--
R
M
L
P
T
V
G
V
K
C
Y
S
W
A
L
---
D
T
V
G
L
F
G
A
-------------------------
R
A
E
D
L
A
R
G
L
L
A
M
T
G
R
S
E
F
S
G
-----------------
I
-
V
P
A
K
A
P
R
---
I
G
V
V
R
--
Q
E
F
A
------------
G
A
V
E
----
P
A
----
A
E
Q
G
L
Q
A
A
I
K
A
A
E
R
A
G
A
S
V
Q
A
I
D
L
P
------------
E
A
V
H
E
A
W
R
I
H
P
I
I
--------
Q
D
-
F
E
A
H
R
A
--------
L
A
W
E
F
S
E
H
H
D
E
I
A
P
M
L
R
A
S
L
D
A
T
V
--------
G
L
T
P
K
--------
E
Y
D
E
A
R
R
I
G
R
R
G
R
R
E
L
G
E
V
F
E
GV
D
V
L
L
T
Y
S
A
P
G
T
A
P
A
K
A
L
A
S
T
G
D
P
R
Y
N
R
L
W
T
L
M
G
N
P
C
V
N
V
P
V
L
K
V
------------------
G
G
L
P
I
G
V
Q
V
I
A
R
F
G
N
D
A
-
H
A
L
A
T
A
W
F
L
E
D
A
L
A
K
-
46
Fugue
50.87
18%
22
- C1 -
-
5JVK
6
?
A:
[10-499]
---------------------------
K
I
Q
L
N
P
V
L
V
S
T
D
I
G
K
K
N
V
A
K
N
-
L
-----
G
E
G
N
M
R
L
T
G
K
L
V
R
Y
G
D
N
L
T
F
S
G
V
A
N
A
G
K
E
L
V
-
I
D
V
T
E
L
G
Y
Y
T
L
E
L
T
L
A
D
N
E
N
I
I
Q
T
A
V
V
N
Y
A
--
V
V
P
E
I
I
D
----
E
E
R
--
P
L
D
M
G
V
C
V
------
H
P
P
K
D
N
D
Y
S
K
T
F
R
L
I
R
M
A
G
F
T
---
R
I
R
T
D
L
A
W
E
H
V
E
P
A
K
G
K
Y
V
M
P
E
H
M
Y
Q
F
--------
V
S
A
S
E
K
E
G
I
--------------
K
P
L
I
V
F
G
Y
------
A
N
A
I
--
A
Y
P
N
G
F
P
T
I
P
F
-------------
P
T
T
--
E
E
S
R
L
G
C
A
N
A
L
A
Y
A
V
---
K
E
M
G
N
R
V
T
------
E
W
E
-----
L
W
N
E
P
N
Y
A
D
P
V
K
D
Y
L
P
L
L
K
V
V
Y
P
T
V
K
K
V
N
P
D
I
T
L
I
S
G
G
G
S
G
--
A
G
G
G
P
G
G
A
F
I
I
P
V
L
D
A
G
G
V
D
F
Q
--
D
G
Y
S
I
HPYMAPNTPDF
G
Y
A
G
TGGP
I
P
----
A
V
N
I
P
T
V
W
P
Y
L
K
K
I
S
E
E
N
L
R
S
D
K
K
E
L
S
V
W
VT
E
I
G
W
N
S
T
T
N
L
D
I
E
Q
A
A
Y
L
A
--------
R
T
-
Y
L
L
S
R
R
H
YMSP
G
V
F
W
Y
D
F
Q
N
D
G
D
T
P
D
N
I
E
H
N
F
G
L
L
R
S
--------
D
F
S
P
K
P
--------
S
Y
Q
A
A
A
V
V
A
S
L
L
K
N
------------
Y
T
F
Q
E
T
L
L
D
G
V
N
K
V
L
A
F
G
Q
D
G
---
E
T
T
F
Y
T
A
W
T
T
K
A
E
G
T
T
I
R
V
K
A
P
T
D
V
D
K
L
R
L
I
D
W
Q
G
C
E
M
P
L
T
V
D
N
G
Y
L
V
L
--
N
L
S
I
L
P
------
Q
Y
L
V
V
K
34
HHSearch
49.44
21%
-371
- C4 -
-
4B86
-
MSL1_HUMAN
B:
[22-56]
----------------------------
L
D
L
I
E
Q
Q
Q
Q
Q
L
Q
A
K
E
K
E
I
E
E
-
L
-----
K
S
E
R
D
T
L
L
A
R
I
E
R
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
45.53
16%
-320
- C4 -
-
1JUN
-
B:
[3-40]
-----------------------------
G
R
I
A
R
L
E
E
K
V
K
T
L
K
A
Q
N
S
E
-
L
-----
A
S
T
A
N
M
L
R
E
Q
V
A
Q
L
K
Q
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
43.46
17%
-249
- C4 -
-
1ZXA
-
KGP1_HUMAN
B:
[9-44]
----------------------------
A
K
I
L
M
L
K
E
E
R
I
K
E
L
E
K
R
L
S
E
-
K
-----
E
E
E
I
Q
E
L
K
R
K
L
H
K
C
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
36.96
14%
-161
* C4 *
-
3HE5
-
?
C:
[3-45]
------------------------
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
-
K
-----
K
D
L
I
A
Y
L
E
K
E
I
A
N
L
R
K
K
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
36.60
11%
-161
- C4 -
-
3HE5
-
?
C:
[2-38]
------------------------------
L
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
-
L
-----
K
K
K
N
L
H
K
K
D
L
I
A
Y
L
E
K
E
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
34.03
12%
34
- C2 -
-
3L2P
4
DNLI3_HUMAN
A:
[1-579]
HMRHKDCL
L
R
E
F
R
K
L
C
A
M
V
A
D
N
P
S
Y
N
T
K
T
Q
I
I
Q
D
F
L
R
K
G
G
D
V
Y
L
T
V
K
L
-
L
L
P
GVI
K
T
V
Y
N
L
N
D
K
Q
I
V
K
L
F
S
R
I
F
N
C
N
P
D
D
M
A
R
D
L
E
Q
G
D
V
S
E
T
I
R
V
F
F
E
Q
S
K
S
F
P
P
A
A
K
S
L
L
T
--
I
Q
--
E
V
D
E
F
L
L
----
R
L
S
K
L
T
-
K
E
D
E
Q
Q
------
Q
A
L
Q
D
I
A
S
R
C
T
A
N
D
L
K
C
I
I
R
L
I
K
H
D
L
K
M
N
S
G
A
K
H
V
L
D
A
L
D
P
N
A
--
Y
E
A
F
-
K
A
S
RN
L
Q
D
V
V
E
R
V
L
H
N
A
Q
E
V
E
L
S
V
Q
A
S
L
MTPV
Q
P
M
L
A
E
A
C
K
S
V
E
Y
A
M
K
K
C
P
N
G
M
F
S
E
I
K
Y
D
G
E
R
V
Q
V
H
K
N
G
D
H
F
S
Y
F
S
R
SL
K
P
V
L
P
H
K
V
A
H
F
K
D
Y
I
---
P
Q
A
F
P
G
G
H
S
M
I
L
D
S
E
V
L
L
I
DNK
T
G
K
P
L
P
F
G
T
L
G
V
H
K
K
A
A
F
---------
Q
D
A
N
V
C
L
F
V
F
D
C
I
Y
FN
D
V
S
L
M
D
-
R
P
L
C
E
R
R
---
K
F
L
H
D
N
M
V
E
I
P
------------
N
R
I
M
----
F
S
----
E
M
K
R
V
T
K
A
L
D
L
A
D
M
I
T
R
V
I
Q
E
G
L
E
G
------------------
L
V
L
K
D
V
K
GTYEPGKR
H
W
-
L
K
V
K
K
D
--------
Y
L
N
M
A
D
T
A
D
L
V
V
L
G
A
F
Y
G
Q
G
--
S
K
G
G
M
M
S
I
F
L
M
G
C
Y
D
--------
P
G
S
Q
K
W
C
T
V
T
K
C
A
G
G
H
-------------
D
D
A
T
L
A
R
L
Q
N
E
L
---
D
M
V
K
I
S
K
A
A
V
W
E
I
T
G
A
E
F
S
K
S
E
A
H
T
A
D
G
I
S
I
R
F
P
R
C
T
R
I
R
D
D
K
D
W
K
----
S
A
T
N
L
--
P
-
Q
L
K
E
L
Y
Q
L
S
K
------
26
HHSearch
33.42
26%
-
- C4 -
-
5U59
-
?
A:
[4-29]
--------------------------------
A
A
L
K
-
E
N
A
A
L
K
E
E
I
A
A
-
L
-----
K
K
E
I
A
A
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
32.63
28%
51
- C4 -
-
2RIW
1
?
A:
[233-311]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
5
PsiBlast_PDB
32.37
28%
52
- C4 -
-
2XN7
2
?
A:
[239-317]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
7
PsiBlast_PDB
32.13
28%
55
- C4 -
-
2RIV
1
THBG_HUMAN
A:
[238-316]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.08
28%
44
- C4 -
-
2XN5
3
?
A:
[239-317]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
8
PsiBlast_PDB
32.02
28%
48
- C4 -
-
2XN3
1
THBG_HUMAN
A:
[238-316]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
6
PsiBlast_PDB
31.82
28%
48
- C4 -
-
2XN6
7
THBG_HUMAN
A:
[239-317]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
P
K
E
G
Q
M
------------
E
S
V
E
A
A
M
S
S
K
T
L
K
--------
K
W
N
R
L
L
Q
K
G
--------
W
V
D
----------------
L
F
V
P
K
F
S
I
S
A
T
Y
D
-
L
G
A
T
--------
L
L
K
M
G
I
Q
H
A
Y
S
E
N
A
D
F
S
G
L
T
E
--
D
N
G
L
K
L
S
N
----------------------------------------------------------------------------------------
42
Fugue
31.34
31%
62
- C4 -
-
3BBP
-
GCC2_HUMAN
D:
[29-66]
----------------------
K
S
A
D
H
L
N
G
L
L
R
E
T
E
A
T
N
A
I
L
M
E
Q
I
K
L
-
L
-----
K
S
E
I
R
R
L
E
R
N
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
31.06
18%
64
- C4 -
-
5FIY
-
PAWR_RAT
D:
[38-82]
--------------------------
D
L
E
K
E
V
L
R
E
R
Q
E
N
L
R
L
T
R
L
M
Q
D
-
K
-----
E
E
M
I
G
K
L
K
E
E
I
D
L
L
N
R
D
L
D
D
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
30.30
18%
64
- C4 -
-
5FIY
-
PAWR_RAT
A:
[38-82]
--------------------------
D
L
E
K
E
V
L
R
E
R
Q
E
N
L
R
L
T
R
L
M
Q
D
-
K
-----
E
E
M
I
G
K
L
K
E
E
I
D
L
L
N
R
D
L
D
D
M
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------