@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3U4U0: (2017-12-27 )
MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQGGNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLAGFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFEQEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIPRKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILLGTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNLISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL
Atome Classification :
(20 SA)
---------------------------------------------------------------------........--.10........20........30......--..40........50........60....-....70........80......--.--.90...-.....100.......110------........120.......130------........140------------........-150..--.....160----........170.....----..180.......190.......200.......210.......-220........230.-.---------------.....240.....-..250--------.....-.-...260--.........270.---......280-------------.......290.......--300--------------------......-..-.-310..-.....320---------......-.330.......---------340-----...------....-------------------------..---------------------------------350....-...360----.........370.......380-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------------------------------------------MF
W
H
F
Y
K
Y
--
R
T
K
I
L
LRNK
S
M
L
F
W
T
L
A
F
P
I
L
L
G
L
M
F
M
A
A
--FGEIDQGGN
L
E
T
I
NT
G
I
V
I
KA
D
Q
T
A
L
S
E
-
N
F
T
T
V
L
E
Q
VEVNDKP
L
F
E
V
Q
E
L
--
S
--
E
VEANE-KL
N
A
D
D
L
A
G
F
Y
L
IDG
S
S
-------
V
S
L
H
VGQA
G
M
S
Q
T
L
M
K
N
V
M
D
-------
Q
F
L
Q
R
IG
I
I
S
-------------
S
K
V
A
EVEN-V
D
L
A
P
--
I
M
T
V
F
E
-Q----EV
S
F
Q
E
V
HAGRNMS
F
K
----
S
F
Y
F
F
T
L
I
G
M
A
I
L
Y
G
T
M
WGVRNV
Q
D
QQANQSSN
G
I
R
L
S
L
IP
R
-
K
Q
-
S
L
V
S
I
A
N
L
A
A
S
F
-
T
---------------
I
V
L
T
E
I
Y
I
M
L
A
V
F
-
R
F
I
----------
Y
QVDF-G-E
R
W
Q
----
W
L
M
I
V
T
A
L
G
S
L
C
A
---
I
L
L
G
T
L
V
G
N
-------------
L
I
PKMNLVQKD
S
I
L
I
S
V
--
T
----------------------
I
A
M
S
F
F
-
A
G
-M-MGS
E
Q
-
V
K
Y
W
I
D
L
H---------IPIVG
Q
-
L
N
L
V
N
L
I
S
E
S
L
---------
Y
-------
K
L
Y
------
F
Y
T
D
-------------------------
L
A
---------------------------------
S
F
Y
T
N
L
L
-
W
L
I
G
------
F
I
F
L
F
A
L
G
N
A
W
M
ERGVRYDAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
66.27
18%
-13
* C3 *
-
4R4X
-
?
A:
[1-546]
-----------------------------------------------------A
Q
T
Y
E
I
T
Y
Q
N
S
F
EGKI
N
Q
N
H
I
I
S
I
T
N
S
D
K
T
L
L
F
N
E
K
I
K
N
K
K
A
D
F
P
F
E
V
N
E
I
N
-
R
K
--
N
N
E
V
S
Q
F
A
F
L
N
--
N
N
E
I
V
K
T
S
D
N
T
I
L
A
K
Q
E
F
K
P
T
S
E
T
G
K
I
L
G
---
Y
N
V
K
K
A
--
V
--
T
S
V
N
S
N
-
T
I
E
V
W
Y
T
N
D
L
K
V
K
G
G
P
S
ILGQDLG
L
V
L
K
T
V
R
N
G
S
S
V
V
E
A
T
S
V
K
K
I
KALDDQ
S
L
F
N
G
K
N
I
T
E
-------------
K
D
A
L
T
Y
K
D
M
I
W
K
S
R
F
I
T
I
P
V
F
E
N
E
----
T
I
N
F
S
D
A
S
K
S
D
Q
V
I
Q
R
F
GNG
T
I
I
L
K
K
V
K
I
P
E
I
K
Q
G
N
T
I
F
V
E
L
K
Q
K
S
N
G
D
A
Y
D
R
T
G
D
V
F
I
I
P
Q
-
E
R
-
A
I
S
Y
Y
T
G
L
T
Q
G
V
-
K
S
L
P
V
Y
Q
N
GNG
K
S
Y
Q
G
V
A
L
T
P
D
Y
L
P
F
I
E
L
M
R
F
F
T
P
FGIGHFNE
K
I
Q
L
K
-
G
-
K
N
W
H
N
N
T
P
Y
R
Q
D
I
T
E
L
R
P
Q
L
S
GKE
I
L
I
G
A
F
I
G
N
YDKG
G
H
Q
I
S
L
E
L
S
I
H
P
D
Q
Q
K
I
V
N
N
N
F
V
L
P
V
--
F
NTTNVMEMA
G
Q
D
Y
PTMFNSDKG
V
E
V
D
F
I
-
L
T
-
K
D
L
K
N
A
Q
-
L
R
Y
I
T
T
G
H
G
GWGAGDEF
V
P
K
E
N
S
-
I
Y
L
D
G
K
L
A
H
A
F
T
P
W
R
TDCGS
Y
-------
R
L
F
NPASGN
F
E
D
G
-------------------------
L
S
---------------------------------
S
S
D
L
S
R
S
N
W
C
P
G
T
I
T
N
P
V
Y
I
N
L
G
N
L
N
A
G
K
H
T
I
Q
V
K
I
P
Q
G
A
P
E
GS
S
Q
S
F
W
N
V
S
G
V
L
L
G
Q
E
H
H
H
H
H
H
HH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
61.03
18%
19
- C4 -
-
4RM6
-
HXUA1_HAEIN
A:
[2-817]
ARDLPQGSSVVV
G
E
A
N
V
S
T
I
GN
K
M
T
I
DQKTP
T
T
Q
I
D
W
H
S
F
D
I
G
QN
K
E
V
E
F
KQPDAN
S
V
A
Y
N
R
V
TGGNAS
Q
I
Q
G
K
L
T
A
--
N
G
K
V
Y
L
A
N
P
N
G
V
I
I
T
Q
G
A
E
I
N
V
A
G
L
F
A
T
T
KD
L
E
R
I
S
E
N
N
K
F
T
R
K
L
K
D
G
Q
V
V
K
E
G
Q
V
I
N
K
-
G
K
I
K
A
K
D
F
V
V
L
N
G
-----------
D
--
K
V
I
N
E
G
-
E
I
D
A
T
N
N
G
K
V
Y
L
S
S
G
Y
N
-------
F
T
F
T
L
S
D
S
S
I
S
V
A
L
E
D
N
A
V
Q
-------
S
I
V
Q
N
E
G
I
I
K
A
G
D
I
T
L
N
A
K
G
R
NQ
A
L
D
S
L
V
M
N
-
N
G
V
L
E
--
A
T
K
V
S
N
-
K
NG
K
V
V
L
S
A
D
D
V
Q
L
N
N
K
S
D
I
K
----
G
E
S
E
V
V
F
T
N
E
N
K
I
K
I
T
S
Q
T
G
S
K
V
T
S
P
K
I
N
F
T
G
K
S
V
N
I
N
G
D
F
G
-
R
D
-
D
--
S
K
A
H
Y
N
E
E
H
-
K
---------------
R
L
D
T
E
V
N
I
D
V
P
D
N
-
E
N
I
----------
R
I
A
E
--
K
-
D
N
T
D
----
S
F
I
Q
T
G
A
L
S
S
L
L
A
---
N
N
----------------------
G
K
V
N
L
K
G
K
D
-
V
N
I
S
G
--
R
----------------------
I
H
I
D
----
S
-
F
-
R
G
S
D
------
S
L
L
K
---------
L
T
N
Q
G
H
-
I
K
I
N
H
A
D
I
H
S
T
---------
G
-------
R
L
F
------
F
I
T
S
-------------------------
L
Q
---------------------------------
N
E
K
D
S
Q
S
-
D
I
T
I
------
T
D
S
K
I
N
L
G
N
G
A
M
G
L
G
R
S
L
D
K
E
NCDNQRWCRTETSQRK
K
F
D
V
H
M
R
N
V
V
F
D
QVD
D
V
V
V
A
GGFK
K
V
N
L
D
N
I
V
A
T
G
K
T
N
F
Y
I
D
GGVSRNNSRYEYGVLD
L
D
K
R
T
L
LSELDQRRRR
W
K
Y
Y
ND
L
D
L
D
M
N
K
A
YWHRFDMRSTIKD
T
E
I
N
I
S
N
S
K
I
N
L
K
N
G
F
V
H
L
L
A
E
K
I
K
L
D
N
S
K
I
D
I
T
F
D
K
D
NSQDISTQINR
L
G
M
N
G
K
V
S
M
V
N
S
H
I
K
I
V
G
D
EKSDISAKAPYAT
M
F
L
I
G
E
L
I
G
E
K
S
S
I
F
V
K
S
HQGYT
F
R
T
D
GD
T
K
I
A
G
KNSKDD
L
K
I
T
A
I
N
TGGRTGKEVIINGAPGSI
A
N
M
A
F
T
I
G
D
N
A
N
T
K
T
T
I
E
N
A
D
I
T
A
L
A
PNGGTA
Y
L
S
S
KG
V
E
I
E
V
N
PN
S
N
F
T
F
F
E
L
PIKGDSTKLS
E
R
G
F
A
R
L
Y
D
K
I
N
GVR
3
HHSearch
52.86
14%
-135
- C2 -
-
5DO7
-
ABCG5_HUMAN
C:
[446-647]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
---------------
F
S
V
V
A
T
M
I
F
S
S
V
C
-
Y
W
T
----------
L
G
L
H
P
E
V
-
A
R
F
G
----
Y
F
S
A
A
L
L
A
P
H
L
I
G
---
E
F
L
T
L
V
L
L
G
-------------
I
-
V
Q
-
N
P
N
I
V
N
S
V
V
A
L
L
--
S
----------------------
I
A
G
V
L
V
G
S
G
-
F
-
L
R
N
I
Q
E
M
P
I
P
F
K
I
-------------
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
I
L
---------
V
-------
V
N
E
------
F
Y
G
L
N
------------------------
F
T
CGSMCAFTQ
G
I
Q
F
I
E
K
TCPGATS----------
R
F
T
M
N
F
L
-
I
L
Y
S
------
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
51.19
14%
-137
- C2 -
-
5DO7
-
ABCG5_HUMAN
A:
[446-647]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
V
S
D
Q
E
S
Q
D
G
L
Y
-
Q
K
-
W
Q
M
M
L
A
Y
A
L
H
V
L
-
P
---------------
F
S
V
V
A
T
M
I
F
S
S
V
C
-
Y
W
T
----------
L
G
L
H
P
E
V
-
A
R
F
G
----
Y
F
S
A
A
L
L
A
P
H
L
I
G
---
E
F
L
T
L
V
L
L
G
-------------
I
-
V
Q
-
N
P
N
I
V
N
S
V
V
A
L
L
--
S
----------------------
I
A
G
V
L
V
G
S
G
-
F
-
L
R
N
I
Q
E
M
P
I
P
F
K
I
-------------
I
S
Y
-
F
T
F
Q
K
Y
C
S
E
I
L
---------
V
-------
V
N
E
------
F
Y
G
L
N
------------------------
F
T
CAFTQ
G
I
Q
F
I
E
K
TCPGATS--------------
R
F
T
M
N
F
L
-
I
L
Y
S
------
F
I
P
A
L
V
I
L
G
I
V
V
F
K
I
R
D
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
44.10
11%
-161
- C2 -
-
5DO7
-
ABCG8_HUMAN
B:
[477-669]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
---------------
E
H
C
A
Y
I
I
I
Y
G
M
P
T
-
Y
W
L
----------
A
N
L
R
P
G
L
-
Q
P
F
L
----
L
H
F
L
L
V
W
L
V
V
F
C
C
---
R
I
M
A
L
A
A
A
A
-------------
L
-
L
P
-
T
F
H
M
A
S
F
F
S
N
A
L
--
Y
----------------------
N
S
F
Y
L
A
-
G
G
-
F
-
M
I
N
L
S
S
L
W
T
V
P
A
W
-------------
I
S
K
-
V
S
F
L
R
W
C
F
E
G
L
---------
M
-------
K
I
Q
------
F
S
R
R
T
Y
K
M
P
L
G
NLTIAVSGD
K
I
L
S
V
M
ELD
S
Y
---------------------------------
P
L
Y
A
I
Y
L
-
I
V
I
G
------
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
43.73
11%
-157
- C2 -
-
5DO7
-
ABCG8_HUMAN
D:
[476-669]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
A
M
L
Y
Y
E
L
E
D
G
L
Y
T
T
-
G
P
Y
F
F
A
K
I
L
G
E
L
-
P
---------------
E
H
C
A
Y
I
I
I
Y
G
M
P
T
-
Y
W
L
----------
A
N
L
R
P
G
L
-
Q
P
F
L
----
L
H
F
L
L
V
W
L
V
V
F
C
C
---
R
I
M
A
L
A
A
A
A
-------------
L
-
L
P
-
T
F
H
M
A
S
F
F
S
N
A
L
--
Y
----------------------
N
S
F
Y
L
A
-
G
G
-
F
-
M
I
N
L
S
S
L
W
T
V
P
A
W
-------------
I
S
K
-
V
S
F
L
R
W
C
F
E
G
L
---------
M
-------
K
I
Q
------
F
S
R
R
T
Y
K
M
P
L
GNL
T
I
A
V
S
GD
K
I
L
S
V
M
ELD
S
Y
---------------------------------
P
L
Y
A
I
Y
L
-
I
V
I
G
------
L
S
G
G
F
M
V
L
Y
Y
V
S
L
R
F
I
K
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
42.88
10%
-179
- C2 -
-
5XJY
-
?
A:
[656-1117]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
M
----
S
R
S
M
P
L
F
M
T
L
A
W
I
Y
S
V
A
V
I
I
K
G
I
V
Y
E
K
E
--
A
R
L
K
E
T
M
R
I
M
G
L
-
D
N
-
S
I
L
W
F
S
W
F
I
S
S
--
L
---------------
I
P
L
L
V
S
A
G
L
L
V
V
I
-
L
K
L
----------
G
N
L
L
P
-
Y
-
S
D
P
S
----
V
V
F
V
F
L
S
V
F
A
V
V
T
---
I
L
Q
C
F
L
I
S
T
-------------
L
-
F
S
-
R
A
N
L
A
A
A
C
G
G
I
I
--
Y
----------------------
F
T
L
Y
L
P
-
Y
V
L
C
-
V
A
W
Q
D
Y
V
G
F
T
L
K
I
-------------
F
A
S
L
L
S
P
V
A
F
G
F
G
C
E
---------
Y
F
A
L
F
EEQ---------------------------------------------------------------------------
G
F
N
L
T
-
T
S
V
S
------
M
M
L
F
D
T
F
L
Y
G
V
M
T
W
Y
I
E
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
42.61
10%
-160
- C2 -
-
5NJ3
1
?
A:
[460-663]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
---------------
M
R
M
L
P
S
I
I
F
T
C
I
V
-
Y
F
M
----------
L
G
L
K
P
-
K
A
D
A
F
F
----
V
M
M
F
T
L
M
M
V
A
Y
S
A
---
S
S
M
A
L
A
I
A
A
-------------
G
-
Q
S
-
V
V
S
V
A
T
L
L
M
T
I
C
--
F
----------------------
V
F
M
M
I
F
-
S
G
-
L
-
L
V
N
L
T
T
I
A
S
W
L
S
W
-------------
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
---------
Q
-------
H
N
E
------
F
L
G
Q
-------------------------
N
F
CPGLNATGNNPCNYATCT
G
E
E
Y
L
V
K
Q
GIDLS
P
W
G
L
W
K
N
H
V
-
A
L
A
C
------
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
42.43
10%
-160
- C2 -
-
5NJG
1
?
B:
[460-663]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
K
L
F
I
H
E
Y
I
S
G
Y
-
Y
R
V
S
S
Y
F
L
G
K
L
L
S
D
L
L
P
---------------
M
R
M
L
P
S
I
I
F
T
C
I
V
-
Y
F
M
----------
L
G
L
K
P
-
K
A
D
A
F
F
----
V
M
M
F
T
L
M
M
V
A
Y
S
A
---
S
S
M
A
L
A
I
A
A
-------------
G
-
Q
S
-
V
V
S
V
A
T
L
L
M
T
I
C
--
F
----------------------
V
F
M
M
I
F
-
S
G
-
L
-
L
V
N
L
T
T
I
A
S
W
L
S
W
-------------
L
Q
Y
-
F
S
I
P
R
Y
G
F
T
A
L
---------
Q
-------
H
N
E
------
F
L
G
Q
-------------------------
N
F
CPGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
G
L
W
K
N
H
V
-
A
L
A
C
------
M
I
V
I
F
L
T
I
A
Y
L
K
L
L
F
L
K
K
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
39.41
30%
14
- C2 -
-
3L4G
1
SYFA_HUMAN
A:
[343-420]
--------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
F
T
P
V
K
Y
F
--
S
I
D
R
V
F
R
N
E
-
T
L
D
A
T
H
L
A
E
F
H
Q
I
E
G
V
------------
V
A
D
H
G
L
T
L
G
H
L
M
G
V
L
R
-------
E
F
F
T
K
L
G
I
T
Q
-------------
L
R
F
K
P
A
Y
N
-
P
Y
T
E
P
--
S
M
E
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
34.18
14%
-60
- C4 -
-
5GAP
-
PRP3_YEAST
G:
[150-467]
------------------------------------------------------------------------
L
L
D
L
S
--
K
F
K
I
Y
Y
D
N
N
H
G
Y
E
W
-------
W
D
T
A
Y
L
D
E
--
K
G
E
L
M
E
K
Y
D
M
N
G
T
S
P
A
----------
E
E
-
K
L
A
E
D
I
D
E
V
D
D
D
D
D
D
E
H
P
S
I
R
Y
--
V
--
A
H
P
L
P
E
-
K
I
N
E
A
K
V
S
----
I
K
A
Y
L
-------
T
Q
H
E
R
K
R
L
R
R
N
R
R
K
M
A
R
E
A
R
-------
E
I
K
I
K
L
G
L
L
P
-------------
K
P
E
P
K
V
K
----
L
S
N
--
M
M
S
V
F
E
-
N
----
D
Q
N
I
T
D
----------------------------
P
T
A
W
--
E
K
V
V
K
D
Q
V
D
L
R
K
R
K
H
L
E
E
N
E
R
R
-
H
E
-
D
A
I
K
R
R
K
E
A
V
N
M
-
N
---------------
V
E
K
P
T
V
Y
-
H
C
K
V
F
-
Q
F
K
----------
N
L
Q
N
P
-
K
-
I
R
F
K
----
L
K
M
N
S
K
E
L
S
------------
L
K
G
L
-------------
C
L
R
I
R
D
--
D
G
P
G
I
I
I
V
V
G
N
E
----------------------
K
S
C
K
F
Y
-
E
N
-
L
-
V
M
-
K
R
-
I
K
W
N
E
D
F
E
---------
L
H
T
N
T
G
-
D
I
K
M
D
M
H
N
N
S
I
---------
S
-------
K
T
W
E
-----
G
Y
L
Q
-------------------------
D
C
---------------------------------
K
F
K
G
W
F
M
-
K
V
C
N
------
D
Q
D
S
L
L
R
T
L
G
Q
F
D
S
E
H
F
Y
S
P
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
33.33
20%
-297
- C2 -
-
5DO7
-
ABCG5_HUMAN
A:
[367-419]
---------------------------------------------------------------------
K
L
G
V
L
L
R
R
--
V
T
R
N
L
V
R
N
K
L
A
V
I
T
R
L
L
Q
N
L
I
M
G
L
F
L
L
F
F
--
V
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
33.17
20%
-336
- C2 -
-
5DO7
-
ABCG5_HUMAN
C:
[367-415]
---------------------------------------------------------------------
K
L
G
V
L
L
R
R
--
V
T
R
N
L
V
R
N
K
L
A
V
I
T
R
L
L
Q
N
L
I
M
G
L
F
L
L
F
F
--
V
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
30.00
40%
154
* C5 *
-
4GUS
-
H33_HUMAN
C:
[1-20]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
T
M
Q
T
A
R
K
S
T
G
G
K
A
----
P
R
-
K
Q
-
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
29.70
32%
-259
* C4 *
-
2L5B
-
A:
[1-31]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
G
A
L
-
P
-
T
Y
W
P
----
W
L
C
A
A
A
Q
V
A
A
L
A
A
---
W
L
L
G
R
--
R
N
-------------
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
27.78
23%
-184
- C2 -
-
5NJG
-
?
B:
[385-424]
---------------------------------------------------------------------
Q
L
R
W
V
S
K
R
--
S
F
K
N
L
L
G
N
P
Q
A
S
I
A
Q
I
I
V
T
V
V
L
G
L
V
I
G
A
I
--
Y
F
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
27.61
23%
-184
- C2 -
-
5NJ3
-
?
A:
[385-424]
---------------------------------------------------------------------
Q
L
R
W
V
S
K
R
--
S
F
K
N
L
L
G
N
P
Q
A
S
I
A
Q
I
I
V
T
V
V
L
G
L
V
I
G
A
I
--
Y
F
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
25.71
17%
-323
* C2 *
-
5NC5
-
?
H:
[7-29]
----------------------------------------------------------------------------------------
S
L
V
F
A
V
I
M
V
P
V
V
M
A
I
I
L
G
L
I
--
Y
G
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
25.21
12%
9
- C2 -
-
2P0S
-
?
B:
[8-62]
------------------------------------------------------------------------------------------------------------------------
D
M
K
T
I
A
I
A
D
R
T
G
-----
E
-
Y
E
Q
L
F
K
E
--
N
----
D
E
F
R
F
V
H
A
EK
T
--
A
E
E
Y
R
K
M
G
A
D
K
S
G
I
D
A
V
L
E
I
R
Q
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
24.83
12%
-4
- C2 -
-
2P0S
1
?
A:
[8-68]
------------------------------------------------------------------------------------------------------------------------
D
M
K
T
I
A
I
A
D
R
T
G
-----
E
-
Y
E
Q
L
F
K
E
--
N
----
D
E
F
R
F
V
H
A
EK
T
--
A
E
E
Y
R
K
M
G
A
D
K
S
G
I
D
A
V
L
E
I
R
Q
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------