@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XWH0: (2017-12-30 )
MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYIEAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNELEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGATTRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGTPRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYGGGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI
Atome Classification :
(20 SA)
.........10........20......-..30........40........-------50------.........60........70........80--........90.---------------------------------------------------.---..----....100.-.------......110.......120..---------.....130.......140.......150.......160.-----------......170.......180.......190.......200.......210...-...-.220........230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTD
E
Y
LLSPESGENE
L
S
L
E
K
SL
R
P
Q
L
L
-
S
Q
Y
I
G
Q
R
K
V
K
Q
E
L
Q
I
Y
I
E
A
ARN-------R-------EEPL
D
H
V
L
L
YGPPGLGK
T
T
M
A
M
V
I
AN
E
M
T
V
N
--
I
RTTSGPAIER---------------------------------------------------P---
G
D
----
L
V
A
I
L
-
N
E-L------EAG
D
V
L
F
I
D
E
I
H
R
L
P
R
V
V
E
E
M
---------
L
Y
S
A
M
E
D
F
Y
V
D
I
M
VGQGPTAHPVHFPLP
P
F
T
L
IGATTRA-----------GMLSA
P
L
R
D
R
F
G
I
I
S
H
M
E
YY
D
E
Q
D
L
Q
E
I
V
L
RSSDI
F
Q
T
E
I
I
E
E
G
A
L
E
I
A
R
RS-RGT-
P
R
-
I
A
N
R
L
L
K
R
V
R
D
F
A
Q
VQGDGKIDR
P
I
A
D
Q
A
L
T
L
L
Q
V
D
Q
A
G
L
D
Y
V
D
Q
K
L
L
R
T
M
I
E
LYGGGPV
G
L
S
T
L
S
V
NIG
E
E
R
E
T
V
E
D
M
Y
E
P
Y
L
I
Q
K
G
F
LKRTPRG
R
I
A
T
A
Y
A
Y
E
HFGYDYHI
7
PsiBlast_PDB
93.42
54%
-128
- C1 -
-
1IN8
1
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
V
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
6
PsiBlast_PDB
92.70
54%
-127
- C1 -
-
1IN6
1
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
R
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
-------------
I
D
I
Q
P
F
T
L
V
G
A
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
134
HHSearch
92.67
54%
-126
* C1 *
-
1IN4
3
RUVB_THEMA
A:
[18-326]
--------------------
F
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
----
4
PsiBlast_PDB
92.65
54%
-126
- C1 -
-
1IN4
3
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
8
PsiBlast_PDB
91.28
54%
-128
- C1 -
-
1IN7
1
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
---------------
I
Q
P
F
T
L
V
G
A
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
A
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
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K
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M
E
V
L
N
I
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D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
5
PsiBlast_PDB
91.21
54%
-121
- C1 -
-
1IN5
1
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
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I
A
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E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
I
M
------------
D
I
Q
P
F
T
L
V
G
S
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
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K
E
L
K
E
I
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A
A
S
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M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
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E
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I
D
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G
L
D
E
F
D
R
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I
L
K
T
I
I
E
I
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G
G
P
V
G
L
N
A
L
A
A
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G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
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A
G
F
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A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
135
HHSearch
91.15
54%
-121
- C1 -
-
1IN5
1
RUVB_THEMA
A:
[18-326]
--------------------
F
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
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I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
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E
I
H
R
L
N
K
A
V
E
E
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---------
L
Y
S
A
I
E
D
F
Q
I
D
I
M
------------
D
I
Q
P
F
T
L
V
G
S
T
T
R
S
-----------
G
L
L
S
S
P
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S
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F
G
I
I
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E
L
D
F
Y
T
V
K
E
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K
E
I
I
K
R
A
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D
A
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A
E
M
I
A
K
R
S
-
R
G
T
-
P
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
----
9
PsiBlast_PDB
90.75
54%
-127
- C1 -
-
1J7K
2
RUVB_THEMA
A:
[19-327]
---------------------
L
R
P
K
S
L
-
D
E
F
I
G
Q
E
N
V
K
K
K
L
S
L
A
L
E
A
A
K
M
-------
R
-------
G
E
V
L
D
H
V
L
L
A
G
P
P
G
L
G
K
T
T
L
A
H
I
I
A
S
E
L
Q
T
N
--
I
H
V
T
S
G
P
V
L
V
K
---------------------------------------------------
Q
---
G
D
----
M
A
A
I
L
-
T
S
-
L
------
E
R
G
D
V
L
F
I
D
E
I
H
R
L
N
K
A
V
E
E
L
---------
L
Y
S
A
I
E
D
F
Q
I
D
I
------------
I
D
I
Q
P
F
T
L
V
G
A
T
T
R
S
-----------
G
L
L
S
S
P
L
R
S
R
F
G
I
I
L
E
L
D
F
Y
T
V
K
E
L
K
E
I
I
K
R
A
A
S
L
M
D
V
E
I
E
D
A
A
A
E
M
I
A
K
R
S
-
R
G
T
-
G
R
-
I
A
I
R
L
T
K
R
V
R
D
M
L
T
V
V
K
A
D
R
I
N
T
D
I
V
L
K
T
M
E
V
L
N
I
D
D
E
G
L
D
E
F
D
R
K
I
L
K
T
I
I
E
I
Y
R
G
G
P
V
G
L
N
A
L
A
A
S
L
G
V
E
A
D
T
L
S
E
V
Y
E
P
Y
L
L
Q
A
G
F
L
A
R
T
P
R
G
R
I
V
T
E
K
A
Y
K
H
L
K
Y
E
---
136
HHSearch
86.36
49%
-116
- C1 -
-
3PFI
1
RUVB_CAMJE
A:
[23-328]
---------------------
L
R
P
S
N
F
-
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
-------
R
-------
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
A
N
--
I
K
T
T
A
A
P
M
I
E
K
---------------------------------------------------
S
---
G
D
----
L
A
A
I
L
-
T
N
-
L
------
S
E
G
D
I
L
F
I
D
E
I
H
R
L
S
P
A
I
E
E
V
---------
L
Y
P
A
M
E
D
Y
R
L
---------
A
Q
T
I
K
I
D
L
P
K
F
T
L
I
G
A
T
T
R
A
-----------
G
M
L
S
N
P
L
R
D
R
F
G
M
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
-
R
S
T
-
P
R
-
I
A
L
R
L
L
K
R
V
R
D
F
A
D
V
N
D
E
E
I
I
T
E
K
R
A
N
E
A
L
N
S
L
G
V
N
E
L
G
F
D
A
M
D
L
R
Y
L
E
L
L
T
A
A
K
-
Q
K
P
I
G
L
A
S
I
A
A
A
L
S
E
D
E
N
T
I
E
D
V
I
E
P
Y
L
L
A
N
G
Y
I
E
R
T
A
K
G
R
I
A
S
A
K
S
Y
S
A
L
K
-----
10
PsiBlast_PDB
84.92
48%
-113
- C1 -
-
3PFI
1
RUVB_CAMJE
A:
[23-332]
---------------------
L
R
P
S
N
F
-
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
-------
R
-------
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
A
N
--
I
K
T
T
A
A
P
M
I
E
K
---------------------------------------------------
S
---
G
D
----
L
A
A
I
L
-
T
N
-
L
------
S
E
G
D
I
L
F
I
D
E
I
H
R
L
S
P
A
I
E
E
V
---------
L
Y
P
A
M
E
D
Y
R
L
---------
A
Q
T
I
K
I
D
L
P
K
F
T
L
I
G
A
T
T
R
A
-----------
G
M
L
S
N
P
L
R
D
R
F
G
M
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
-
R
S
T
-
P
R
-
I
A
L
R
L
L
K
R
V
R
D
F
A
D
V
N
D
E
E
I
I
T
E
K
R
A
N
E
A
L
N
S
L
G
V
N
E
L
G
F
D
A
M
D
L
R
Y
L
E
-
L
L
T
A
A
K
Q
K
P
I
G
L
A
S
I
A
A
A
L
S
E
D
E
N
T
I
E
D
V
I
E
P
Y
L
L
A
N
G
Y
I
E
R
T
A
K
G
R
I
A
S
A
K
S
Y
S
A
L
K
L
N
Y
E
-
2
PsiBlast_PDB
80.21
58%
-16
- C1 -
-
1HQC
1
RUVB_THET8
A:
[5-314]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
A
N
S
-
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
----
124
Fugue
80.16
57%
-16
- C1 -
-
1HQC
1
RUVB_THET8
A:
[5-318]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
A
N
S
-
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
P
P
P
V
1
PsiBlast_PDB
80.09
58%
-20
- C1 -
-
1IXS
1
RUVB_THET8
B:
[5-314]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
A
N
S
-
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
A
T
E
L
A
Y
R
H
L
G
Y
----
137
HHSearch
77.25
58%
-18
- C1 -
-
1IXS
1
RUVB_THET8
B:
[4-302]
-------------------
L
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
-
A
N
S
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
----------------
21
PsiBlast_CBE
76.96
58%
-13
- C1 -
-
1HQC
1
RUVB_THET8
B:
[5-314]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
A
N
S
-
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
Y
----
138
HHSearch
76.00
58%
-13
- C1 -
-
1HQC
1
RUVB_THET8
B:
[5-313]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
-
A
N
S
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
P
T
E
L
A
Y
R
H
L
G
-----
3
PsiBlast_PDB
74.59
57%
-24
- C1 -
-
1IXR
1
RUVB_THET8
C:
[5-312]
--------------------
A
L
R
P
K
T
L
-
D
E
Y
I
G
Q
E
R
L
K
Q
K
L
R
V
Y
L
E
A
A
K
A
-------
R
-------
K
E
P
L
E
H
L
L
L
F
G
P
P
G
L
G
K
T
T
L
A
H
V
I
A
H
E
L
G
V
N
--
L
R
V
T
S
G
P
A
I
E
K
---------------------------------------------------
P
---
G
D
----
L
A
A
I
L
A
N
S
-
L
------
E
E
G
D
I
L
F
I
D
E
I
H
R
L
S
R
Q
A
E
E
H
---------
L
Y
P
A
M
E
D
F
V
M
D
I
V
I
G
Q
G
P
A
A
R
T
I
R
L
E
L
P
R
F
T
L
I
G
A
T
T
R
P
-----------
G
L
I
T
A
P
L
L
S
R
F
G
I
V
E
H
L
E
Y
Y
T
P
E
E
L
A
Q
G
V
M
R
D
A
R
L
L
G
V
R
I
T
E
E
A
A
L
E
I
G
R
R
S
-
R
G
T
-
M
R
-
V
A
K
R
L
F
R
R
V
R
D
F
A
Q
V
A
G
E
E
V
I
T
R
E
R
A
L
E
A
L
A
A
L
G
L
D
E
L
G
L
E
K
R
D
R
E
I
L
E
V
L
I
L
R
F
G
G
G
P
V
G
L
A
T
L
A
T
A
L
S
E
D
P
G
T
L
E
E
V
H
E
P
Y
L
I
R
Q
G
L
L
K
R
T
P
R
G
R
V
A
T
E
L
A
R
R
H
L
------
152
HHSearch
41.88
20%
-12
- C1 -
-
3D8B
2
B:
[77-305]
--------------------
H
G
P
P
V
N
W
-
E
D
I
A
G
V
E
F
A
K
A
T
I
K
E
I
V
V
W
P
M
L
RPDIFTG
L
-------
R
G
P
P
K
G
I
L
L
F
G
P
P
G
T
G
K
T
L
I
G
K
C
I
A
S
Q
S
G
A
T
--
F
F
S
I
S
A
S
S
L
T
-----------------------------------------------------E
G
E
K
M
----
V
R
A
L
F
-
A
V
-
A
R
C
----
Q
Q
P
A
V
I
F
I
D
E
I
D
S
L
L
S
--------------
S
R
R
I
K
T
E
F
L
V
Q
-
L
D
G
------
A
----
E
D
R
I
L
V
V
G
A
T
N
R
P
-----------
Q
E
I
D
E
A
A
R
R
R
L
V
K
R
L
Y
I
P
L
P
E
A
S
A
R
K
Q
I
V
I
N
L
M
S
K
E
Q
C
C
L
S
E
E
E
I
E
Q
I
V
Q
Q
S
-
D
A
F
S
G
A
-
D
M
T
Q
L
C
R
E
A
S
L
G
P
I
---------------------------------------------------------------------------------------------------
147
HHSearch
39.79
20%
-22
- C1 -
-
3VFD
-
SPAST_HUMAN
A:
[105-337]
-----------------
I
V
D
N
G
T
A
V
K
F
-
D
D
I
A
G
Q
D
L
A
K
Q
A
L
Q
E
I
V
I
L
P
S
L
-------
R
PELFTGL
R
A
P
A
R
G
L
L
L
F
G
P
P
G
N
G
K
T
M
L
A
K
A
V
A
A
E
S
N
A
T
--
F
F
N
I
S
A
A
S
L
------------------------------------------------------G
E
-
K
L
----
V
R
A
L
F
-
A
V
-
A
R
E
----
L
Q
P
S
I
I
F
I
D
Q
V
D
S
L
L
------DA
S
R
R
L
K
T
E
F
L
I
E
F
D
G
V
Q
-------------------
R
V
L
V
M
G
A
T
N
R
P
-----------
Q
E
L
D
E
A
V
L
R
R
F
I
K
R
V
Y
V
S
L
P
N
E
E
T
R
L
L
L
L
K
N
L
L
C
K
Q
G
S
P
L
T
Q
K
E
L
A
Q
L
A
R
M
T
-
D
G
Y
-
S
G
S
D
L
T
A
L
A
K
D
A
A
L
G
P
I
---------------------------------------------------------------------------------------------------
157
HHSearch
39.66
22%
-12
- C1 -
-
3UK6
1
?
G:
[23-330]
-------
G
A
H
S
H
I
R
G
L
G
L
D
D
A
L
E
P
R
Q
A
S
Q
G
M
V
G
Q
L
A
A
R
R
A
A
G
V
V
L
E
M
I
R
E
-------
G
-------
K
I
A
G
R
A
V
L
I
A
G
Q
P
G
T
G
K
T
A
I
A
M
G
M
A
Q
A
L
G
P
D
T
P
F
T
A
I
A
G
S
E
I
F
S
LEMS
K
T
E
A
L
T
Q
A
F
R
R
S
I
G
V
R
I
KATVS
L
H
E
I
D
V
I
N
SRTQGFLALFSGDTGEI
K
---
S
E
V
R
E
Q
I
N
A
K
V
-
A
E
-
W
R
E
E
GA
E
I
I
P
G
V
L
F
I
D
E
V
H
M
L
D
I
E
S
F
S
F
---------
L
N
R
A
L
E
S
D
M
------------------
A
P
V
L
I
M
A
T
N
R
G
I
TRIRGTSYQSP
H
G
I
P
I
D
L
L
D
R
L
-
L
I
V
S
T
T
P
Y
S
E
K
D
T
K
Q
I
L
R
I
R
C
E
E
E
D
V
E
M
S
E
D
A
Y
T
V
L
T
R
I
G
L
E
T
S
-
L
R
-
Y
A
I
Q
L
I
T
A
A
S
L
V
C
R
K
R
K
G
T
E
V
Q
V
D
D
I
K
R
V
Y
S
L
F
--------------------------------------------------------------------------------