@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XWK0: (2017-12-30 )
MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKTTTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVIPEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVILMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEIIQCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTPMKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI
Atome Classification :
(37 SA)
.........10...-.-.-.---..--20........30........40........50........60..---.....--.-------------70...----.....-80.....-...90........100-.-------....-..110......---.120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240...-....250.......260.......270.......280.......290.......300.......310.......320
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MTK
L
I
E
F
K
H
V
Q
K
KY-D-G-
K
---
Y
V
--
I
DDL
N
L
A
I
KKG
E
I
F
V
L
VGPSGSG
K
T
T
T
L
K
M
INGLSKPSAG
D
I
Y
F
---KGKSL--N-------------EY
N
L
Q
----
K
M
R
W
N
-
M
G
Y
V
L
Q
Q
-
I
ALFPT
M
T
V
K
Q
N
I
E
V
I
-
P
-------
E
M
LG-
W
E
K
Q
K
R
A
D
R
V
D
---
E
L
L
Q
KVGLS
P
D
I
Y
R
DRMPRELSGGEQ
Q
R
I
G
I
I
R
A
IAASP
D
V
I
L
MDEPFSALDPI
S
R
N
S
L
Q
E
L
V
L
S
L
H
E
ELG
T
T
I
V
F
V
TH
N
M
E
E
A
I
KLG
D
R
I
A
F
MKDG
E
I
I
QCD
T
P
E
Q
L
LMNP
K
N
D
Y
V
R
H
F
FDEPKQT-KEWR
V
E
D
L
V
VN
G
Y
F
L
N
EI
P
E
N
A
R
Q
QVCFDT
P
M
K
E
V
Y
S
L
L
S
VYP
S
I
V
I
V
E
KQRSIGS
L
T
S
K
E
I
F
A
F
L
S
REEEGNENI
2
PsiBlast_PDB
80.22
39%
-115
- C1 -
-
2IT1
-
?
A:
[4-248]
----
I
K
L
E
N
I
V
K
K
F
-
G
-
N
-
F
---
T
A
--
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
---
D
E
K
D
V
--
T
-------------
E
--
L
P
----
P
K
D
R
N
-
V
G
L
V
F
Q
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
-------
E
L
R
K
-
A
P
R
E
E
I
D
K
K
V
R
---
E
V
A
K
M
L
H
I
--
D
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
P
P
M
N
F
V
E
A
K
V
E
D
---------------------------------------------------------------------
171
HHSearch
76.51
39%
-116
- C1 -
-
2IT1
-
?
A:
[1-236]
-
M
V
E
I
K
L
E
N
I
V
K
K
F
-
G
-
N
-
F
---
T
A
--
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
---
D
E
K
D
V
--
T
-------------
E
L
P
P
------
K
D
R
N
-
V
G
L
V
F
Q
N
-
W
A
L
Y
P
H
M
T
V
Y
K
N
I
A
F
P
-
L
-------
E
L
R
K
-
A
P
R
E
E
I
D
K
K
V
R
---
E
V
A
K
M
L
H
I
D
--
K
L
L
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
K
Y
K
F
V
G
G
F
L
G
N
---------------------------------------------------------------------------------
158
HHSearch
75.77
35%
-128
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[2-237]
--
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
-
E
-
V
---
V
V
--
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
---
G
E
K
R
M
--
N
-------------
D
T
P
------
P
A
E
R
G
-
V
G
M
V
F
Q
S
-
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
F
G
-
L
-------
K
L
A
G
-
A
K
K
E
V
I
N
Q
R
V
N
---
Q
V
A
E
V
L
Q
L
A
--
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
--------------------------------------------------------------------------------
12
PsiBlast_PDB
74.95
37%
-125
- C1 -
-
4XIG
-
?
S:
[1-238]
M
V
A
S
V
S
I
Q
N
V
V
K
R
Y
-
D
-
K
-
T
---
T
V
--
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
---
D
G
R
V
I
--
N
-------------
D
--
L
A
----
P
K
D
R
D
-
V
A
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
F
G
-
L
-------
R
L
K
R
-
T
K
K
S
V
I
D
A
A
V
K
---
T
A
A
D
I
L
G
L
Q
P
L
L
--
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
--------------------------------------------------------------------------------
159
HHSearch
74.93
35%
-127
- C1 -
-
2AWN
1
MALK_ECOLI
B:
[2-237]
--
A
S
V
Q
L
Q
N
V
T
K
A
W
-
G
-
E
-
V
---
V
V
--
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
---
G
E
K
R
M
--
N
-------------
D
T
P
------
P
A
E
R
G
-
V
G
M
V
F
Q
S
-
Y
A
L
Y
P
H
L
S
V
A
E
N
M
S
F
G
-
L
-------
K
L
A
G
-
A
K
K
E
V
I
N
Q
R
V
N
---
Q
V
A
E
V
L
Q
L
A
--
H
L
L
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
D
R
F
V
A
G
F
I
G
S
P
--------------------------------------------------------------------------------
13
PsiBlast_PDB
74.80
37%
-126
- C1 -
-
4XTC
-
?
S:
[1-238]
M
V
A
S
V
S
I
Q
N
V
V
K
R
Y
-
D
-
K
-
T
---
T
V
--
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
---
D
G
R
V
I
--
N
-------------
D
--
L
A
----
P
K
D
R
D
-
V
A
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
F
G
-
L
-------
R
L
K
R
-
T
K
K
S
V
I
D
A
A
V
K
---
T
A
A
D
I
L
G
L
Q
P
L
L
--
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
--------------------------------------------------------------------------------
10
PsiBlast_PDB
74.73
37%
-123
- C1 -
-
4TQU
-
?
S:
[1-238]
M
V
A
S
V
S
I
Q
N
V
V
K
R
Y
-
D
-
K
-
T
---
T
V
--
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
---
D
G
R
V
I
--
N
-------------
D
--
L
A
----
P
K
D
R
D
-
V
A
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
F
G
-
L
-------
R
L
K
R
-
T
K
K
S
V
I
D
A
A
V
K
---
T
A
A
D
I
L
G
L
Q
P
L
L
--
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
--------------------------------------------------------------------------------
163
HHSearch
74.16
37%
-119
- C1 -
-
2YYZ
1
?
A:
[2-236]
--
P
S
I
R
V
V
N
L
K
K
Y
F
-
G
-
K
-
V
---
K
A
--
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
F
---
D
D
V
L
V
--
N
-------------
D
I
P
P
------
K
Y
R
E
-
V
G
M
V
F
Q
N
-
Y
A
L
Y
P
H
M
T
V
F
E
N
I
A
F
P
-
L
-------
R
A
R
R
-
I
S
K
D
E
V
E
K
R
V
V
---
E
I
A
R
K
L
L
I
D
--
N
L
L
D
R
K
P
T
Q
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
V
Y
D
S
P
K
N
M
F
V
A
S
F
I
G
N
---------------------------------------------------------------------------------
173
HHSearch
73.16
35%
-125
- C1 -
-
3D31
-
?
B:
[1-231]
---
M
I
E
I
E
S
L
S
R
K
W
-
K
---
N
---
F
S
--
L
D
N
L
S
L
K
V
E
S
G
E
Y
F
V
I
L
G
P
T
G
A
G
K
T
L
F
L
E
L
I
A
G
F
H
V
P
D
S
G
R
I
L
L
---
D
G
K
D
V
--
T
-------------
D
L
S
------
P
E
K
H
D
-
I
A
F
V
Y
Q
N
-
Y
S
L
F
P
H
M
N
V
K
K
N
L
E
F
G
-
M
-------
R
M
K
K
-
I
---
K
D
P
K
R
V
L
---
D
T
A
R
D
L
K
I
E
--
H
L
L
D
R
N
P
L
T
L
S
G
G
E
Q
Q
R
V
A
L
A
R
A
L
V
T
N
P
K
I
L
L
L
D
E
P
L
S
A
L
D
P
R
T
Q
E
N
A
R
E
M
L
S
V
L
H
K
K
N
K
L
T
V
L
H
I
T
H
D
Q
T
E
A
R
I
M
A
D
R
I
A
V
V
M
D
G
K
L
I
Q
V
G
K
P
E
E
I
F
E
K
P
V
E
G
R
V
A
S
F
V
G
F
E
--------------------------------------------------------------------------------
25
PsiBlast_CBE
72.97
38%
-18
- C1 -
-
3C4J
2
?
B:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
15
PsiBlast_PDB
72.91
38%
-29
- C1 -
-
2OLJ
3
?
A:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
19
PsiBlast_PDB
72.83
38%
-24
- C1 -
-
3C4J
2
?
A:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M
------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
161
HHSearch
72.47
37%
-127
- C1 -
-
4TQU
-
?
T:
[1-238]
M
V
A
S
V
S
I
Q
N
V
V
K
R
Y
-
D
-
K
-
T
---
T
V
--
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
I
---
D
G
R
V
I
--
N
-------------
D
L
A
------
P
K
D
R
D
-
V
A
M
V
F
Q
N
-
Y
A
L
Y
P
H
L
N
V
R
D
N
I
S
F
G
-
L
-------
R
L
K
R
-
T
K
K
S
V
I
D
A
A
V
K
---
T
A
A
D
I
L
G
L
Q
--
P
L
L
E
R
K
P
S
D
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
L
F
L
H
P
A
N
T
F
V
A
S
F
I
G
S
P
--------------------------------------------------------------------------------
30
PsiBlast_CBE
72.21
38%
-21
- C1 -
-
2OLK
1
?
D:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
32
PsiBlast_CBE
71.85
38%
-24
- C1 -
-
2OLK
2
?
B:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
1
PsiBlast_PDB
71.75
41%
-2
- C1 -
-
1Z47
-
?
A:
[15-248]
----
I
E
F
V
G
V
E
K
I
Y
P
G
-
G
-
A
---
R
S
--
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
---
G
G
K
R
V
--
T
-------------
D
L
P
P
Q
----
K
R
--
N
-
V
G
L
V
F
Q
N
-
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
-------
R
E
K
R
-
V
P
K
D
E
M
D
A
R
V
R
---
E
L
L
R
F
M
R
L
--
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
---------------------------------------------------------------------------------
58
PsiBlast_CBE
71.71
38%
-29
- C1 -
-
3C41
2
?
K:
[2-238]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
-----------------------------------------------------------------------------------
16
PsiBlast_PDB
71.57
38%
-24
- C1 -
-
2OLK
1
?
A:
[22-261]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
---------------------------------------------------------------------------------
169
HHSearch
71.38
41%
-2
- C1 -
-
1Z47
-
?
A:
[13-249]
--
M
T
I
E
F
V
G
V
E
K
I
Y
-
P
-
G
G
A
---
R
S
--
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
---
G
G
K
R
V
--
T
-------------
D
L
P
------
P
Q
K
R
N
-
V
G
L
V
F
Q
N
-
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
-
L
-------
R
E
K
R
-
V
P
K
D
E
M
D
A
R
V
R
---
E
L
L
R
F
M
R
L
E
--
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
I
G
E
S
--------------------------------------------------------------------------------
5
PsiBlast_PDB
71.20
39%
-26
- C1 -
-
4YMU
1
?
J:
[1-238]
---
M
I
F
V
N
D
V
Y
K
N
F
-
G
-
S
-
L
---
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
---
D
G
V
K
I
--
N
NG-----------
K
V
N
I
N
----
K
V
R
Q
K
-
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-
P
-------
V
K
V
K
-
K
M
N
K
K
E
A
E
E
L
A
V--
D
L
L
A
K
V
G
L
L
D
K
--
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
---------------------------------------------------------------------------------
23
PsiBlast_CBE
70.78
39%
-29
- C1 -
-
4YMV
1
?
A:
[1-238]
---
M
I
F
V
N
D
V
Y
K
N
F
-
G
-
S
-
L
---
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
---
D
G
V
K
I
--
N
NG-----------
K
V
N
I
N
----
K
V
R
Q
K
-
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-
P
-------
V
K
V
K
-
K
M
N
K
K
E
A
E
E
L
A
V
--
D
L
L
A
K
V
G
L
L
D
K
--
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
---------------------------------------------------------------------------------
24
PsiBlast_CBE
70.43
39%
-26
- C1 -
-
4YMU
1
?
A:
[1-238]
---
M
I
F
V
N
D
V
Y
K
N
F
-
G
-
S
-
L
---
E
V
--
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
---
D
G
V
K
I
--
N
NG-----------
K
V
N
I
N
----
K
V
R
Q
K
-
V
G
M
V
F
Q
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
-
P
-------
V
K
V
K
-
K
M
N
K
K
E
A
E
E
L
A
V
--
D
L
L
A
K
V
G
L
L
D
K
--
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
K
N
E
R
T
R
E
F
L
S
K
---------------------------------------------------------------------------------
59
PsiBlast_CBE
70.14
38%
-26
- C1 -
-
3C41
2
?
J:
[2-238]
--
Q
M
I
D
V
H
Q
L
K
K
S
F
-
G
-
S
-
L
---
E
V
--
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
---
D
G
I
N
L
KA
K
-------------
D
T
N
L
N
----
K
V
R
E
E
-
V
G
M
V
F
Q
R
-
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
-
P
M------
K
V
R
K
-
W
P
R
E
K
A
E
A
K
A
M
---
E
L
L
D
K
V
G
L
K
D
K
A
H
--
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
-----------------------------------------------------------------------------------
176
HHSearch
68.49
39%
-9
- C1 -
-
2D62
1
?
A:
[4-244]
-
M
A
E
V
K
L
I
N
I
W
K
R
F
-
G
-
D
-
V
---
T
A
--
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
---
E
D
N
L
V
--
A
-------------
D
P
E
K
G
V
F
V
P
P
K
E
R
D
-
V
A
M
V
F
Q
S
-
Y
A
L
Y
P
H
M
T
V
Y
D
N
I
A
F
P
-
L
-------
K
L
R
K
-
V
P
K
Q
E
I
D
K
R
V
R
---
E
V
A
E
M
L
G
L
T
E
--
L
L
N
R
K
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
Q
Q
V
G
T
P
D
E
V
Y
Y
K
P
V
N
T
F
V
A
G
F
I
G
----------------------------------------------------------------------------------
101
PsiBlast_CBE
62.37
35%
0
- C1 -
-
1B0U
1
HISP_SALTY
A:
[12-253]
---------
L
H
K
R
Y
-
G
-
G
-
H
---
E
V
--
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
---
N
G
Q
N
I
--
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
----
L
L
R
T
R
-
L
T
M
V
F
Q
H
-
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I------
Q
V
L
G
-
L
S
K
H
D
A
R
E
R
A
L
---
K
Y
L
A
K
V
G
I
D
-
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
S
P
R
L
Q
Q
F
L
-----------------------------------------------------------------------------------
106
PsiBlast_CBE
56.59
33%
-59
- C1 -
-
4HLU
1
ECFA1_THEMA
C:
[12-242]
----
I
E
L
N
S
V
S
F
R
Y
-
N
-
G
-
D
---
Y
V
--
L
K
D
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
---
D
G
S
P
A
--
D
-------------
P
F
L
L
R
----
K
---
N
-
V
G
Y
V
F
Q
N
P
S
S
Q
I
I
G
A
T
V
E
E
D
V
A
F
S
-
L
-------
E
I
M
G
-
L
D
E
S
E
M
R
K
R
I
K
---
K
V
L
E
L
V
G
L
S
G
L
A
A
A
D
--
P
L
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
P
S
Q
R
E
I
F
Q
V
L
E
S
L
K
N
E
-
G
K
G
I
I
L
V
T
H
E
L
E
Y
L
D
D
M
-
D
F
I
L
H
I
S
N
G
T
I
D
F
C
G
S
W
E
E
--------
F
V
E
R
E
F
D
D
V
E
I
P
-
F
K
W
K
L
-----------------------------------------------------------------------
96
PsiBlast_CBE
53.89
32%
-21
- C1 -
-
4P33
6
LPTB_ECOLI
A:
[6-226]
-------
K
N
L
A
K
A
Y
-
K
-
G
-
R
---
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
---
D
D
D
D
I
--
S
-------------
L
L
P
L
H
A
---
R
A
R
R
G
-
I
G
Y
L
P
Q
E
-
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
-
L
-------
Q
I
R
D
D
L
S
A
E
Q
R
E
D
R
A
N
---
E
L
M
E
E
F
H
I
--
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
---------------------------------------------------------------------------------------------
95
PsiBlast_CBE
53.33
32%
-21
- C1 -
-
4P33
5
LPTB_ECOLI
B:
[6-226]
-------
K
N
L
A
K
A
Y
-
K
-
G
-
R
---
R
V
--
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
---
D
D
D
D
I
--
S
-------------
L
L
P
L
H
A---
R
A
R
R
G
-
I
G
Y
L
P
Q
E
-
A
S
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
-
L
-------
Q
I
R
D
D
L
S
A
E
Q
R
E
D
R
A
N
---
E
L
M
E
E
F
H
I
--
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
I
L
Q
D
---------------------------------------------------------------------------------------------
88
PsiBlast_CBE
50.04
38%
32
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-223]
---
M
V
K
L
K
N
V
T
K
T
Y
-
K
M
G
-
E
EII
Y
A
--
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
DNI
K
T
N
D
L
--
D
-------------
D
D
E
L
T
----
K
I
R
R
D
K
I
G
F
V
F
Q
Q
-
F
N
L
I
P
L
L
T
A
L
E
N
V
E
-
L
-
P
LIFKYRG
A
M
S
G
-
E
E
R
R
K
R
A
L
------
E
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
---------------------------------------------------------------------------------------------------------
135
PsiBlast_CBE
40.36
32%
-52
- C1 -
-
5L22
2
?
B:
[348-545]
------------------------
V
--
L
R
N
I
N
M
R
I
L
P
G
E
F
V
A
I
I
G
P
S
G
S
G
K
S
S
L
V
R
T
I
L
G
I
W
L
P
V
H
G
T
V
E
I
---
D
G
A
D
L
--
K
-------------
Q
W
D
R
D
----
Y
F
G
K
F
-
V
G
Y
L
P
Q
D
-
I
E
L
F
E
G
-
T
V
A
E
N
I
A
R
F
-
G
-------
E
-
L
D
-
S
E
K
I
I
E
A
A
K
L
S
GA
H
D
V
I
I
K
L
P
D
G
Y
D
T
Y
I
G
P
G
G
I
T
L
S
G
G
Q
R
Q
R
I
A
L
A
R
A
L
Y
G
N
P
R
I
V
I
L
D
E
P
D
S
N
L
D
E
Q
G
E
Q
A
L
Y
N
A
L
I
E
L
K
K
R
K
V
T
T
I
I
-
V
S
H
R
I
-
R
L
L
N
L
V
D
K
I
A
I
M
Q
D
G
T
L
---------------------------------------------------------------------------------------------------------
143
PsiBlast_CBE
38.82
31%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
B:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------
142
PsiBlast_CBE
38.82
31%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
C:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------
144
PsiBlast_CBE
38.81
31%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
A:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------
141
PsiBlast_CBE
38.81
31%
-
- C1 -
-
3B5Z
2
MSBA_SALTY
D:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------
136
PsiBlast_CBE
38.70
32%
-52
- C1 -
-
5L22
2
?
A:
[348-545]
------------------------
V
--
L
R
N
I
N
M
R
I
L
P
G
E
F
V
A
I
I
G
P
S
G
S
G
K
S
S
L
V
R
T
I
L
G
I
W
L
P
V
H
G
T
V
E
I
---
D
G
A
D
L
--
K
-------------
Q
W
D
R
D
----
Y
F
G
K
F
-
V
G
Y
L
P
Q
D
-
I
E
L
F
E
G
-
T
V
A
E
N
I
A
R
F
-
G
-------
E
-
L
D
-
S
E
K
I
I
E
A
A
K
L
S
GA
H
D
V
I
I
K
L
P
D
G
Y
D
T
Y
I
G
P
G
G
I
T
L
S
G
G
Q
R
Q
R
I
A
L
A
R
A
L
Y
G
N
P
R
I
V
I
L
D
E
P
D
S
N
L
D
E
Q
G
E
Q
A
L
Y
N
A
L
I
E
L
K
K
R
K
V
T
T
I
I
-
V
S
H
R
I
-
R
L
L
N
L
V
D
K
I
A
I
M
Q
D
G
T
L
---------------------------------------------------------------------------------------------------------
145
PsiBlast_CBE
38.66
31%
-
- C1 -
-
3B5Y
2
MSBA_SALTY
D:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------
146
PsiBlast_CBE
38.64
31%
-
- C1 -
-
3B5Y
2
MSBA_SALTY
C:
[342-566]
----
L
E
F
R
N
V
T
F
T
Y
-
P
-
G
-
R
---
E
V
PA
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
I
L
M
---
D
G
H
D
L
--
R
-------------
E
Y
T
L
A
----
S
L
R
N
Q
-
V
A
L
V
S
Q
N
-
V
H
L
F
N
D
-
T
V
A
N
N
I
A
Y
A
R
T
-------
E
E
Y
S
-
R
E
Q
I
E
E
A
A
R
M
A
YAM
D
F
I
N
K
M
D
N
G
L
D
T
I
I
G
E
N
G
V
L
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
--
R
T
S
L
V
I
A
H
R
L
-
S
T
I
E
Q
A
D
E
I
V
V
V
E
D
G
I
I
V
E
R
G
T
H
S
E
L
L
-----------------------------------------------------------------------------------------------