@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XWS2: (2017-12-31 )
MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVNPMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIGYNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTFAQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLDISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPIHVIEKLFD
Atome Classification :
(33 SA)
.........10........20........30........40...----.....50....---....60........70........80........90........100.......110.......120.......130.......140.......150....-..---.160...---....170.......180........190.......200.......210.......220.......230.......240.......250.......260.......270.......280..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MISGQ
T
K
L
A
G
L
FADPASH
S
L
S
P
L
M
HNTAFEANNI
D
A
V
Y
L
A
F
Q
VN----
P
M
N
L
K
Q
A
V
E
S
I
---
R
T
F
D
M
LG
V
N
LSMPNK
T
A
V
I
P
Y
L
D
E
V
S
Q
E
A
Q
L
I
G
A
V
N
T
I
V
HEKG
R
L
I
G
YNTD
G
A
G
F
M
Q
S
V
Q
E
AGI
S
I
K
K
K
K
M
T
L
L
GAGGA
A
K
A
V
T
V
Q
AALDGA
E
E
I
V
V
Y
KRN-N
Q
---
T
F
A
Q
V
K
E
---
T
F
E
Q
LSYRTS
C
K
I
K
V
R
-
D
F
A
D
T
H
Q
L
R
K
D
L
K
ES
C
L
L
V
NATDIGMGKKINQSPL
L
D
I
S
M
M
HEN
L
A
V
F
D
L
IYAP
R
E
T
R
L
L
K
E
A
K
K
VGAKGYNG
L
G
M
L
I
YQ
G
A
I
A
F
E
L
WTKEKM
P
I
H
V
I
E
K
LFD
25
PsiBlast_CBE
96.83
45%
-114
- C3 -
-
3TOZ
1
AROE_LISMO
D:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
27
PsiBlast_CBE
96.32
45%
-111
- C3 -
-
3TOZ
1
AROE_LISMO
B:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
1
PsiBlast_PDB
96.25
45%
-111
- C3 -
-
3TOZ
2
AROE_LISMO
A:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
26
PsiBlast_CBE
96.18
45%
-112
- C3 -
-
3TOZ
1
AROE_LISMO
C:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
2
PsiBlast_PDB
96.02
45%
-112
- C3 -
-
3TNL
2
AROE_LISMO
A:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
30
PsiBlast_CBE
95.99
45%
-112
- C3 -
-
3TNL
1
AROE_LISMO
B:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
28
PsiBlast_CBE
95.93
45%
-112
- C3 -
-
3TNL
1
AROE_LISMO
D:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
22
PsiBlast_CBE
95.19
45%
-111
- C3 -
-
3TOZ
1
AROE_LISMO
G:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
23
PsiBlast_CBE
95.13
45%
-111
- C3 -
-
3TOZ
1
AROE_LISMO
F:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
21
PsiBlast_CBE
94.78
45%
-109
- C3 -
-
3TOZ
1
AROE_LISMO
H:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
29
PsiBlast_CBE
94.03
45%
-111
- C3 -
-
3TNL
2
AROE_LISMO
C:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
24
PsiBlast_CBE
93.95
45%
-110
- C3 -
-
3TOZ
1
AROE_LISMO
E:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
---
F
Y
A
N
A
E
K
---
T
V
E
K
I
N
S
K
T
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
31
PsiBlast_CBE
90.07
38%
-103
- C3 -
-
3T4E
1
YDIB_SALTY
B:
[28-307]
--
T
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
Y
T
Y
M
A
F
E
V
D
----
N
T
T
F
A
S
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
M
R
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
-
D
D
---
F
F
E
K
A
V
A
---
F
A
K
R
V
N
E
N
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
I
G
D
V
S
L
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
--
3
PsiBlast_PDB
89.97
36%
-107
- C3 -
-
1VI2
1
YDIB_ECOLI
A:
[7-285]
---
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
E
V
D
----
N
D
S
F
P
G
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
-
D
E
---
F
F
D
K
A
L
A
---
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
4
PsiBlast_PDB
89.60
36%
-97
- C3 -
-
1NPD
1
YDIB_ECOLI
A:
[3-283]
-
V
T
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
E
V
D
----
N
D
S
F
P
G
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
-
D
E
---
F
F
D
K
A
L
A
---
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
6
PsiBlast_PDB
89.52
38%
-102
- C3 -
-
3T4E
1
YDIB_SALTY
A:
[30-307]
----
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
Y
T
Y
M
A
F
E
V
D
----
N
T
T
F
A
S
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
M
R
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
-
D
D
---
F
F
E
K
A
V
A
---
F
A
K
R
V
N
E
N
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
I
G
D
V
S
L
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
--
5
PsiBlast_PDB
88.62
36%
-103
- C3 -
-
1O9B
1
YDIB_ECOLI
A:
[7-283]
-----
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
E
V
D
----
N
D
S
F
P
G
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
-
D
E
---
F
F
D
K
A
L
A
---
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
--
40
HHSearch
88.08
45%
-52
- C3 -
-
3TNL
2
AROE_LISMO
A:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
F
Y
A
N
A
E
K
T
V
E
---
K
I
N
S
K
T
---
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
41
HHSearch
87.86
45%
-52
- C3 -
-
3TOZ
1
AROE_LISMO
G:
[33-314]
-
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
Y
V
Y
L
A
F
E
V
G
----
D
K
E
L
K
D
V
V
Q
G
F
---
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
E
A
G
H
D
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
-
D
D
FYA
N
A
E
K
T
V
E
---
K
I
N
S
K
T
---
D
C
K
A
Q
L
F
-
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
K
P
F
E
G
E
T
L
L
P
S
A
D
M
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
T
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-
39
HHSearch
85.18
39%
-47
- C3 -
-
1NPD
1
YDIB_ECOLI
B:
[3-284]
-
V
T
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
F
T
Y
M
A
F
E
V
D
----
N
D
S
F
P
G
A
I
E
G
L
---
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
G
F
D
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
-
D
E
---
F
F
D
K
A
L
A
FAQ
R
V
N
E
N
---
T
D
C
V
V
T
V
T
-
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
M
-
11
PsiBlast_PDB
83.34
35%
-128
- C3 -
-
2HK9
3
AROE_AQUAE
A:
[7-268]
M
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
E
I
N
----
P
E
E
L
K
K
A
F
E
G
F
---
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
I
P
E
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
-
K
V
F
L
W
N
R
T
-
K
E
---
K
A
I
K
L
A
Q
---
K
F
-
P
L
E
V
V
N
S
P
E
-----
E
V
I
D
K
V
Q
---------
V
I
V
N
T
T
S
V
G
L
--
K
D
E
D
P
E
I
F
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
--
K
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
Y
S
V
A
E
R
---
35
PsiBlast_CBE
83.20
35%
-125
- C3 -
-
2HK9
2
AROE_AQUAE
B:
[7-268]
M
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
E
I
N
----
P
E
E
L
K
K
A
F
E
G
F
---
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
I
P
E
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
-
K
V
F
L
W
N
R
T
-
K
E
---
K
A
I
K
L
A
Q
---
K
F
-
P
L
E
V
V
N
S
P
E
-----
E
V
I
D
K
V
Q
---------
V
I
V
N
T
T
S
V
G
L
--
K
D
E
D
P
E
I
F
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
--
K
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
Y
S
V
A
E
R
---
33
PsiBlast_CBE
83.14
35%
-121
- C3 -
-
2HK9
2
AROE_AQUAE
D:
[7-268]
M
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
E
I
N
----
P
E
E
L
K
K
A
F
E
G
F
---
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
I
P
E
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
-
K
V
F
L
W
N
R
T
-
K
E
---
K
A
I
K
L
A
Q
---
K
F
-
P
L
E
V
V
N
S
P
E
-----
E
V
I
D
K
V
Q
---------
V
I
V
N
T
T
S
V
G
L
--
K
D
E
D
P
E
I
F
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
--
K
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
Y
S
V
A
E
R
---
34
PsiBlast_CBE
80.53
35%
-120
- C3 -
-
2HK9
2
AROE_AQUAE
C:
[7-268]
M
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
A
V
Y
L
A
F
E
I
N
----
P
E
E
L
K
K
A
F
E
G
F
---
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
K
S
L
I
P
E
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
-
K
V
F
L
W
N
R
T
-
K
E
---
K
A
I
K
L
A
Q
---
K
F
-
P
L
E
V
V
N
S
P
E
-----
E
V
I
D
K
V
Q
---------
V
I
V
N
T
T
S
V
G
L
--
K
D
E
D
P
E
I
F
N
Y
D
L
I
K
K
D
H
V
V
V
D
I
I
Y
--
K
E
T
K
L
L
K
K
A
K
E
K
G
A
K
L
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
Y
S
V
A
E
R
---
56
HHSearch
77.88
39%
-105
* C3 *
-
2EV9
1
AROE_THET8
B:
[1-256]
-----
M
L
R
F
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
----
L
E
A
L
P
G
R
L
K
E
V
---
R
-
R
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
-
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
G
L
R
-------
A
--
V
-
P
-------
L
E
K
A
R
E
A
R
L
L
V
N
A
T
R
V
G
L
E
D
P
-
S
A
S
P
L
-
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
L
L
P
D
P
S
G
M
E
E
A
--
55
HHSearch
76.77
39%
-103
- C3 -
-
2D5C
1
AROE_THET8
A:
[1-256]
-----
M
L
R
F
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
----
L
E
A
L
P
G
R
L
K
E
V
---
R
-
R
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
-
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
G
L
R
-------
A
--
V
-
P
-------
L
E
K
A
R
E
A
R
L
L
V
N
A
T
R
V
G
L
E
D
P
-
S
A
S
P
L
-
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
L
L
P
D
P
S
G
M
E
E
A
--
7
PsiBlast_PDB
75.69
43%
-66
- C3 -
-
1NVT
1
AROE_METJA
A:
[6-268]
M
I
N
A
K
T
K
V
I
G
L
I
G
H
P
V
E
H
S
F
S
P
I
M
H
N
A
A
F
K
D
K
G
L
N
Y
V
Y
V
A
F
D
V
L
----
P
E
N
L
K
Y
V
I
D
G
A
---
K
A
L
G
I
V
G
F
N
V
T
I
P
H
K
I
E
I
M
K
Y
L
D
E
I
D
K
D
A
Q
L
I
G
A
V
N
T
I
K
I
E
D
G
K
A
I
G
Y
N
T
D
G
I
G
A
R
M
A
L
E
E
E
I
G
R
V
K
D
K
N
I
V
I
Y
G
A
G
G
A
A
R
A
V
A
F
E
L
A
K
D
--
N
N
I
I
I
A
N
R
T
V
E
K
---
A
E
A
L
A
K
E
---
I
A
E
K
L
N
K
K
F
G
E
E
V
K
F
S
-------
G
L
D
V
D
L
D
G
V
D
I
I
I
N
A
T
P
I
G
M
Y
P
N
I
D
V
E
P
I
V
K
A
E
K
L
R
E
D
M
V
V
M
D
L
I
Y
N
P
L
E
T
V
L
L
K
E
A
K
K
V
N
A
K
T
I
N
G
L
G
M
L
I
Y
Q
G
A
V
A
F
K
I
W
T
--------------
32
PsiBlast_CBE
75.59
43%
-61
- C3 -
-
1NVT
1
AROE_METJA
B:
[6-268]
M
I
N
A
K
T
K
V
I
G
L
I
G
H
P
V
E
H
S
F
S
P
I
M
H
N
A
A
F
K
D
K
G
L
N
Y
V
Y
V
A
F
D
V
L
----
P
E
N
L
K
Y
V
I
D
G
A
---
K
A
L
G
I
V
G
F
N
V
T
I
P
H
K
I
E
I
M
K
Y
L
D
E
I
D
K
D
A
Q
L
I
G
A
V
N
T
I
K
I
E
D
G
K
A
I
G
Y
N
T
D
G
I
G
A
R
M
A
L
E
E
E
I
G
R
V
K
D
K
N
I
V
I
Y
G
A
G
G
A
A
R
A
V
A
F
E
L
A
K
D
--
N
N
I
I
I
A
N
R
T
V
E
K
---
A
E
A
L
A
K
E
---
I
A
E
K
L
N
K
K
F
G
E
E
V
K
F
S
-------
G
L
D
V
D
L
D
G
V
D
I
I
I
N
A
T
P
I
G
M
Y
P
N
I
D
V
E
P
I
V
K
A
E
K
L
R
E
D
M
V
V
M
D
L
I
Y
N
P
L
E
T
V
L
L
K
E
A
K
K
V
N
A
K
T
I
N
G
L
G
M
L
I
Y
Q
G
A
V
A
F
K
I
W
T
--------------
38
PsiBlast_CBE
54.71
37%
-18
- C3 -
-
2D5C
1
AROE_THET8
B:
[10-244]
--------------
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
LEA
L
P
G
R
L
K
E
V
R
R
A
F
---
R
-----
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
G
P
A
L
V
L
G
A
G
--
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
---
G
L
R
A
V
P
L
E
K
A
R
--------------
E
A
R
L
L
V
N
A
T
R
V
G
L
-----
A
S
P
-
L
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
16
PsiBlast_PDB
54.63
37%
1
- C3 -
-
2D5C
1
AROE_THET8
A:
[10-244]
--------------
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
LEA
L
P
G
R
L
K
E
V
R
R
A
F
---
R
-----
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
G
P
A
L
V
L
G
A
G
--
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
---
G
L
R
A
V
P
L
E
K
A
R
--------------
E
A
R
L
L
V
N
A
T
R
V
G
L
-
E
D
P
S
A
S
P
-
L
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
17
PsiBlast_PDB
54.56
37%
1
- C3 -
-
2EV9
2
AROE_THET8
A:
[10-244]
--------------
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
LEA
L
P
G
R
L
K
E
V
R
R
A
F
---
R
-----
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
G
P
A
L
V
L
G
A
G
--
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
---
G
L
R
A
V
P
L
E
K
A
R
--------------
E
A
R
L
L
V
N
A
T
R
V
G
L
-
E
D
P
S
A
S
P
-
L
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
37
PsiBlast_CBE
54.29
37%
-2
- C3 -
-
2EV9
1
AROE_THET8
B:
[10-244]
--------------
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
G
S
Y
E
A
W
D
T
P
LEAL
P
G
R
L
K
E
V
R
R
A
F
---
R
-----
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
A
G
G
I
P
L
K
G
P
A
L
V
L
G
A
G
--
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
-
P
Q
---
R
A
L
A
L
A
E
---
E
F
---
G
L
R
A
V
P
L
E
K
A
R
--------------
E
A
R
L
L
V
N
A
T
R
V
G
L
-
E
D
P
S
A
S
P
-
L
P
A
E
L
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
V
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
--------------
13
PsiBlast_PDB
49.65
33%
-26
- C3 -
-
3DOO
1
AROE_STAEQ
A:
[5-248]
----------
V
I
G
N
P
I
S
H
S
L
S
P
L
M
H
H
A
N
F
Q
S
L
N
L
E
N
T
Y
E
A
I
N
V
-----
P
V
N
Q
F
Q
D
I
K
K
I
I
S
E
K
S
I
D
--
G
F
N
V
T
I
P
H
K
E
R
I
I
P
Y
L
D
D
I
N
E
Q
A
K
S
V
G
A
V
N
T
V
L
V
K
D
G
K
W
I
G
Y
N
T
D
G
I
G
Y
V
N
G
L
K
Q
I
Y
E
G
I
E
D
A
Y
I
L
I
L
G
A
G
G
A
S
K
G
I
--------
A
N
E
L
--
Y
K
I
V
-
R
P
---
T
L
T
V
A
N
R
---
T
M
S
R
F
N
N
W
S
L
N
I
N
K
I
N
L
S
H
A
E
S
H
-----
L
D
E
F
D
I
I
I
N
T
T
P
-----------
V
I
S
L
N
R
L
A
S
H
T
L
V
S
D
I
V
Y
N
P
Y
K
T
P
I
L
I
E
A
E
Q
R
G
N
P
I
Y
N
G
L
D
M
F
V
H
Q
G
A
E
S
F
K
I
W
T
--------------